Read Excerpt - Giada De Laurentiis`s Recipe for Adventure

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Annexure III-A

Course Content of Biological Sciences

Special Meeting of Senate 08.06.2012 Final Draft

AcSIR-Biological Cluster 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15.

Final Draft

CSIR-CCMB CSIR-CDRI CSIR-CFTRI CSIR-CIMAP CSIR-IGIB CSIR-IHBT CSIR-IICB CSIR-IICT CSIR-IIIM CSIR-IITR CSIR-IMTECH CSIR-NBRI CSIR-NCL CSIR-NEIST CSIR-NIIST

Level 100 (Minimum 4 credits required) Course number

Title

L-T-P-C

BIO-1-001

Biostatistics (Compulsory)

1-0-0-1

BIO-1-002

Computation/bioinformatics (Compulsory)

1-0-0-1

BIO-1-003

Basic Chemistry (Compulsory)

1-0-0-1

BIO-1-004

Research Methodology, Communication/ethics/safety (Compulsory)

1-0-0-1

BIO-IICT-105 BIO-IICT-106

COMMUNICATION AND WRITING SKILLS LABORATORY SAFETY

BIO-NCL-1-521

Research Methodology (Compulsory)

2-0-0-2

BIO-NCL-1-522 BIO-NCL-1-523 BIO-NCL-1-524 BIO-NCL-1-525 BIO-NCL-1-526 BIO-NCL-1-527

Analytical Methods and Instrumentation (Compulsory) Basic Mathematics and Numerical Methods Introduction to Nanoscience & Nanotechnology Basic Chemistry for Interdisciplinary Sciences Introduction to Chemical Biology Basic techniques in biology

2-0-0-2 2-0-0-2 1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1

Research Methodology

1-0-0-1

Research communication

1-0-0-1

Bio-statistics

1-0-0-1

Laboratory safety

1-0-0-1

BIO-NEIST-1591 BIO-NEIST-1592 BIO-NEIST-1593 BIO-NEIST-1594

Level 200 (4 credits: 1 compulsory + 3 optional) Course number

Title

BIO-CCMB-2-001 BIO-CDRI-2-001 BIO-CIMAP-2-001 BIO-IICB-2-001 BIO-IIIM-2-001 BIO-IITR-2-001 BIO-NBRI-2-001 BIO-IMT-2-001 BIO-IITR-2-001 BIO-IICT-2-001 BIO-CSMCRI-2001

Biotechniques Biotechniques Biotechniques Biotechniques Biotechniques Biotechniques Biotechniques Biotechniques Biotechniques Biotechniques Biotechniques

(compulsory) (compulsory) (compulsory) (compulsory) (compulsory) (compulsory) (compulsory) (compulsory) (compulsory) (compulsory) (compulsory)

1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1

BIO-NIIST-2-001 BIO-IHBT-2-001

Biotechniques and Instrumentation (compulsory)

1-0-0-1

Biotechniques and Instrumentation (compulsory)

1-0-0-1

Final Draft

L-T-P-C and and and and and and and and and and and

Instrumentation Instrumentation Instrumentation Instrumentation Instrumentation Instrumentation Instrumentation Instrumentation Instrumentation Instrumentation Instrumentation

BIO-CCMB-2-002 BIO-CDRI-2-002 BIO-CIMAP-2-002 BIO-IHBT-2-002 BIO-IICB-2-002 BIO-IMT-2-002 BIO-CSMCRI-2002

Biology Biology Biology Biology Biology Biology Biology

of of of of of of of

Macromolecules Macromolecules Macromolecules Macromolecules Macromolecules Macromolecules Macromolecules

2-0-0-2 2-0-0-2 2-0-0-2 2-0-0-2 2-0-0-2 2-0-0-2 2-0-0-2

BIO-CCMB-2-003 BIO-CIMAP-2-003 BIO-IHBT-2-003 BIO-NBRI-2-003 BIO-IMT-2-003 BIO-IITR-2-003 BIO-CSMCRI-2003

Biology Biology Biology Biology Biology Biology Biology

of of of of of of of

Inheritance Inheritance Inheritance Inheritance Inheritance Inheritance Inheritance

2-0-0-2 2-0-0-2 2-0-0-2 1-0-0-1 2-0-0-2 1-0-0-1 2-0-0-2

BIO-CCMB-2-004 BIO-CDRI-2-004 BIO-CIMAP-2-004 BIO-IICB-2-004 BIO-IIIM-2-004 BIO-IMT-2-004 BIO-IHBT-2-004

Biology Biology Biology Biology Biology Biology Biology

of of of of of of of

Infection Infection Infection Infection Infection Infection Infection

2-0-0-2 2-0-0-2 1-0-0-1 2-0-0-2 2-0-0-2 2-0-0-2 2-0-0-2

BIO-CCMB-2-005 BIO-CIMAP-2-005 BIO-IGIB-2-005 BIO-IHBT-2-005 BIO-NBRI-2-005 BIO-IMT-2-005 BIO-CSMCRI-2005

Genomics: Genomics: Genomics: Genomics: Genomics: Genomics: Genomics:

BIO-CCMB-2-006 BIO-CDRI-2-006 BIO-CIMAP-2-006 BIO-IHBT-2-006 BIO-IICB-2-006 Bio-IGIB-2-006 BIO-IMT-2-006 BIO-CSMCRI-2006

Protein Protein Protein Protein Protein Protein Protein Protein

science and proteomics Science and Proteomics Science and Proteomics Science and Proteomics Science and Proteomics Science and Proteomics Science and Proteomics Science and Proteomics

2-0-0-2 2-0-0-2 2-0-0-2 2-0-0-2 2-0-0-2 1-1-0-2 2-0-0-2 2-0-0-2

BIO-NIIST-2-006

Protein Science and Proteomics

2-0-0-2

BIO-CIMAP-2-007 BIO-IMT-2-007

Systems Biology Systems Biology

1-0-0-1 1-0-0-1

BIO-CDRI-2-008 BIO-CIMAP-2-008 BIO-IITR-2-008

Xenobiotic Interaction and Response Xenobiotic Interaction and Response Xenobiotic Interaction and Response

2-0-0-2 1-0-0-1 2-0-0-2

BIO-CCMB-2-009 BIO-CIMAP-2-009 BIO-IHBT-2-009 BIO-IIIM-2-009 BIO-NBRI-2-009 BIO-CSMCRI-2009

Plant-Microbe Plant-Microbe Plant-Microbe Plant-Microbe Plant-Microbe Plant-Microbe

2-0-0-2 2-0-0-2 2-0-0-2 2-0-0-2 1-0-0-1 2-0-0-2

Final Draft

Information Information Information Information Information Information Information

flow flow flow flow flow flow flow

Interaction Interaction Interaction Interaction Interaction Interaction

in Biological in Biological in Biological in Biological in Biological in Biological in Biological

Systems Systems Systems Systems Systems Systems Systems

2-0-0-2 2-0-0-2 1-1-0-2 2-0-0-2 1-0-0-1 2-0-0-2 2-0-0-2

BIO-CIMAP-2-010 BIO-IHBT-2-010 BIO-NBRI-2-010 BIO-CSMCRI-2010

Plant Plant Plant Plant

BIO-CDRI-2-011 BIO-CIMAP-2-011 BIO-IIIM-2-011

Molecular Therapeutics Molecular Therapeutics Molecular Therapeutics

2-0-0-2 1-0-0-1 2-0-0-2

BIO-CDRI-2-012 BIO-IICB-2-012 BIO-IIIM-2-012 BIO-NBRI-2-012 BIO-IMT-2-012 BIO-IITR-2-012

Cell Cell Cell Cell Cell Cell

2-0-0-2 2-0-0-2 2-0-0-2 1-0-0-1 2-0-0-2 2-0-0-2

BIO-CDRI-2-013 BIO-IIIM-2-013 BIO-IMT-2-013 BIO-IICT-2-013

Chemical Chemical Chemical Chemical

BIO-CIMAP-2-015 BIO-IHBT-2-015 BIO-IICT-2-015

Crop Protection Crop Protection Crop Protection

1-0-0-1 1-0-0-1 1-0-0-1

BIO-CIMAP-2-016 BIO-IHBT-2-016 BIO-NBRI-2-016

Developmental Biology-Plants Developmental Biology-Plants Developmental Biology-Plants

1-0-0-1 1-0-0-1 1-0-0-1

BIO-CCMB-2-017 BIO-CDRI-2-017 BIO-CIMAP-2-017 BIO-NBRI-2-017

Epigenetics Epigenetics Epigenetics Epigenetics

2-0-0-2 2-0-0-2 2-0-0-2 1-0-0-1

BIO-CDRI-2-018 BIO-NBRI-2-018

Homeostasis and feedback in biological systems Homeostasis and feedback in biological systems

1-0-0-1 1-0-0-1

BIO-IHBT-2-019 BIO-CSMCRI-2019

In Vitro Development and Morphogenesis in Plants In Vitro Development and Morphogenesis in Plants

1-0-0-1 1-0-0-1

BIO-CDRI-2-020 BIO-IMT-2-020

Molecular and Cellular Mechanisms of Defense Molecular and Cellular Mechanisms of Defense

1-0-0-1 2-0-0-2

BIO-CIMAP-2-021 BIO-IHBT-2-021 BIO-NBRI-2-021 BIO-CSMCRI-2021

Molecular Molecular Molecular Molecular

1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1

BIO-CCMB-2-022 BIO-IITR-2-022

Stem cells, regeneration and aging Stem cells, regeneration and aging

1-0-0-1 1-0-0-1

BIO-IHBT-2-023 BIO-CSMCRI-2023

Natural Resource Management Natural Resource Management

1-1-0-2 1-1-0-2

BIO-CIMAP-2-024 BIO-IHBT-2-024

Bioresources and Bioprospection Bioresources and Bioprospection

1-0-0-1 1-0-0-1

Final Draft

Environment Environment Environment Environment

Interaction Interaction Interaction Interaction

Signaling Signaling Signaling Signaling Signaling Signaling Biology biology biology biology

and and and and

Chromatin Organization Chromatin Organization Chromatin Organization Chromatin Organization

Breeding of Plants Breeding of Plants breeding of plants breeding of plants

1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1

1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1

BIO-NBRI-2-025 BIO-IMT-2-025

Biodiversity Biodiversity

1-0-0-1 1-0-0-1

BIO-IMT-2-026 BIO-IICB-2-026

Bioinformatics Bioinformatics

2-0-0-2 2-0-0-2

BIO-IHBT-2-027 BIO-CSMCRI-2027

Bioresource Production Systems Bioresource Production Systems

1-1-0-2 1-1-0-2

BIO-CCMB-2-101

Self organizations in biology

1-0-0-1

BIO-CDRI-2-136

Dosage Form Design

1-0-0-1

BIO-CFTRI-2-172 BIO-CFTRI-2-173 BIO-CFTRI-2-174 BIO-CFTRI-2-175 BIO-CFTRI-2-176 BIO-CFTRI-2-171 BIO-CFTRI-2-177 BIO-CFTRI-2-178 BIO-CFTRI-2-179 BIO-CFTRI-2-180 BIO-CFTRI-2-181 BIO-CFTRI-2-182

Basics of Food Microbiology Significance of Food Preservation Thermal Processing of Foods Canning of Foods Controlled and Modified Atmosphere Storage of Foods Instrumental Techniques Functional Preservatives Hurdle Technology Infestation Control and Grain Storage Animal Products Technology Spices and Plantation Products Microbial Fermentations

1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1

BIO-CIMAP-2-206 BIO-CIMAP-2-207 BIO-CIMAP-2-208

2-0-0-2 1-0-0-1 2-0-0-2

BIO-CIMAP-2-209

Crop Production Systems Intellectual Property Management Applied and fundamental aspects of In Vitro Plant/Cell/Tissue/ Organ Culture Crop Modelling and System Research

BIO-IGIB-2-276 BIO-IGIB-2-277 BIO-IGIB-2-278

The host and the invaders: the eternal battle The nature of chemical and biological diversity Dynamic nature of biology

1-1-0-2 1-1-0-2 1-1-0-2

BIO-IHBT-2-311 BIO-IHBT-2-312 BIO-IHBT-2-313

Nutrigenomics Advances in protected cultivation of flower crops Biofetilizer Technology

1-0-0-2 2-1-0-3 1-0-0-1

BIO-IICB-2-346

Molecular and Cellular Immunology

2-0-0-2

BIO-IICT-251 BIO-IICT-252 BIO-IICT-253 BIO-IICT-254 BIO-IICT-255

Techniques for identifying Newer Pesticide Molecules Techniques for identifying Newer Drug Molecules Proteomics and its Application Principles of Pharmacology and Toxicology Environmental and Microbial Technology

1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1

BIO-IITR-2-416

System Immunology

1-0-2-2

BIO-IMT-2-451

Biochemical Engineering

1-0-0-1

BIO-NBRI-2-486

Plant morphogenesis and regeneration

1-0-0-1

BIO-NCL-2-521

Advanced Techniques in biology (Compulsory)

2-0-0-2

BIO-NCL-2-522 BIO-NCL-2-523

Introduction to infectious diseases Mathematics and statistics for biologists

2-0-0-2 2-0-0-2

Final Draft

2-0-0-2

BIO-NCL-2-524 BIO-NCL-2-525 BIO-NCL-2-526 BIO-NCL-2-527 BIO-NCL-2-528 BIO-NCL-2-529

Structure determination and analysis of biomolecules Concepts in Microbiology Concepts in Plant Biotechnology Advances in Nanoscience and Nanotechnology Advances in Chemical Biology Advances in Biomaterials

2-0-0-2 2-0-0-2 2-0-0-2 3-0-0-3 3-0-0-3 3-0-0-3

BIO-NEIST-2-591 BIO-NEIST-2-592 BIO-NEIST-2-593 BIO-NEIST-2-594 BIO-NEIST-2-595

Biodiversity and Environmental Studies Natural resources Advances in plant biology Microbial biotransformation Plant-Microbe interactions

1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1

BIO-NIIST-256 BIO-NIIST-257 BIO-NIIST-258 BIO-NIIST-259 BIO-NIIST-260

Basics and Applied Microbiology Basic Molecular Biology Bioprospecting and Biochemical Pharmacology Fundamentals of Food Processing Cell biology and Tissue Engineering

2-0-0-2 2-0-0-2 2-0-0-2 2-0-0-2 2-0-0-2

Level 300 (4 credits: 1 compulsory + 3 optional) Course number BIO-CCMB-3-001 BIO-CDRI-3-001 BIO-CIMAP-3-001 BIO-IHBT-3-001 BIO-IICB-3-001 BIO-NBRI 3-001 BIO-CFTRI-3-001 BIO-IICT-3-001 BIO-IITR-3-001 BIO-CSMCRI-3001 BIO-NIIST-3-001

Title Seminar Seminar Seminar Seminar Seminar Seminar Seminar Seminar Seminar Seminar

Seminar Course (compulsory)

1-0-0-1

BIO-CDRI-3-002 BIO-IICB-3-002 BIO-IIIM-3-002 BIO-IHBT-3-002

Cancer Cancer Cancer Cancer

1-0-0-1 2-0-0-2 2-0-0-2 1-0-0-1

BIO-CIMAP-3-003 BIO-IHBT-3-003 BIO-IICB-3-003 BIO-NBRI 3-003

Cell Cell Cell Cell

BIO-CIMAP-3-004 BIO-IHBT-3-004 BIO-IMT-3-004

Frontiers of Biology: Synthetic Biology Frontiers of Biology: Synthetic Biology Frontiers of Biology: Synthetic Biology

1-0-0-1 1-0-0-1 1-0-0-1

BIO-CIMAP-3-005 BIO-IHBT-3-005 BIO-IMT-3-005 BIO-CSMCRI-3005 BIO-NIIST-3-005

Advanced Advanced Advanced Advanced

2-0-0-2 2-0-0-2 2-0-0-2 2-0-0-2

Introductive Bioinformatics

2-0-0-2

BIO-CDRI-3-006 BIO-IICB-3-006

Microbial Pathogenesis Microbial Pathogenesis

2-0-0-2 1-0-0-1

Final Draft

Course Course Course Course Course Course Course Course Course Course

(compulsory) (compulsory) (compulsory) (compulsory) (compulsory) (compulsory) (compulsory) (compulsory) (compulsory) (compulsory)

Biology Biology biology biology

and and and and

Tissue Engineering Tissue Engineering Tissue Engineering tissue engineering

Bioinformatics Bioinformatics Bioinformatics Bioinformatics

L-T-P-C 1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1

1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1

BIO-CCMB-3-007 BIO-IHBT-3-007 BIO-IICT-3-007

Nanobiology Nanobiology Nanobiology

1-0-0-1 1-0-0-1 1-0-0-1

BIO-CDRI-3-008 BIO-IICB-3-008

Neurobiology Neurobiology

2-0-0-2 2-0-0-2

BIO-CIMAP-3-009 BIO-IHBT-3-009 BIO-CSMCRI-3009

Gene Environment Interaction Gene Environment Interaction Gene Environment Interaction

1-0-0-1 1-0-0-1 1-0-0-1

BIO-CIMAP-3-010 BIO-CSMCRI-3010

Advances in Gene Silencing Advances in Gene Silencing and Epigenetics

1-0-0-1 1-0-0-1

BIO-IHBT-3-011 BIO-CSMCRI-3011 BIO-NIIST-3-011

Microbial Diversity and Habitat Ecology Microbial Diversity and Habitat Ecology

1-0-0-1 1-0-0-1

Microbial Diversity and Ecology

2-0-0-2

BIO-IITR-3-012 BIO-IICT-3-012

Environmental toxicology Environmental toxicology

1-0-2-2 1-0-0-1

BIO-CIMAP-3-013 BIO-IHBT-3-013

Advances in Crop Disease Management Advances in Crop Disease Management

1-0-0-1 1-0-0-1

BIO-CIMAP-3-014 BIO-CSMCRI-3014

Integrated Pest Management Integrated Pest Management

1-0-0-1 1-0-0-1

BIO-CCMB-3-101 BIO-CCMB-3-102 BIO-CCMB-3-103 BIO-CCMB-3-104 BIO-CCMB-3-105 BIO-CCMB-3-106

Brain and behavior Genome organization NMR Micro-imaging and Spectroscopy Mass spectroscopy in biology Conservation biology Drug Discovery

1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1

BIO-CDRI-3-136 BIO-CDRI-3-137 BIO-CDRI-3-138 BIO-CDRI-3-139 BIO-CDRI-3-140 BIO-CDRI-3-141

Transcription and Gene Regulation Biol and Therapeutics of Life Style Disorders Animal Models in Biomedical Research Pharmacokinetics and metabolism Approaches to Drug Delivery An Intro to Drug Discovery & Development

1-0-0-1 2-0-0-2 1-0-0-1 1-0-0-1 2-0-0-2 1-0-0-1

BIO-CFTRI-3171 BIO-CFTRI-3172 BIO-CFTRI-3173 BIO-CFTRI-3174 BIO-CFTRI-3175 BIO-CFTRI-3176 BIO-CFTRI-3177 BIO-CFTRI-3178 BIO-CFTRI-3179 BIO-CFTRI-3180 BIO-CFTRI-3181 BIO-CFTRI-3182 BIO-CFTRI-3183

Technology of Cereals and Pulses Technology of Fruits and Vegetables Food Biotechnology Functional Foods Nutraceuticals Dietary Supplements Convenience and Wellness Foods Prebiotics and Probiotics Fermented Foods and Beverages Sensory Profiling of Foods Microbial Kinetics Food Safety Food Based Nutritional Significance

1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1

Final Draft

BIO-CFTRI-3184

Food Chain Establishment

1-0-0-1

BIO-CIMAP-3-206 BIO-CIMAP-3-207 BIO-CIMAP-3-208

Anti microbial agents and drug resistance Drug delivery and Pharmaceutical formulations In-vitro secondary metabolite production and biotransformation

1-0-0-1 1-0-0-1 1-0-0-1

BIO-CIMAP-3-209 BIO-CIMAP-3-210 BIO-CIMAP-3-211 BIO-CIMAP-3-212

Plant Pathogenesis Biology & Chemistry of Natural Products Biology of inflammation and diseases Soil and crop management

2-0-0-2 2-0-0-2 1-0-0-1 2-0-2-3

BIO-CSMCRI-3241 BIO-CSMCRI-3242 BIO-CSMCRI-3243 BIO-CSMCRI-3244

Fermentation Technology

1-0-0-1

Salt tolerance mechanism in plants and Genetic manipulation

2-0-0-2

Biology of marine macroalgae

2-0-0-2

Wasteland biology and reclamation

2-0-0-2

BIO-IGIB-3-276 BIO-IGIB-3-277 BIO-IGIB-3-278 BIO-IGIB-3-279 BIO-IGIB-3-280 BIO-IGIB-3-281 BIO-IGIB-3-282

Playing with Genomes Complex Disease Genomics Death and Disease: The cellular dilema The microworld Space and Time in Biological Systems Immortality: the everlasting quest Electronics for Biologists

1-0-2-2 1-1-0-2 1-1-0-2 1-1-0-2 2-0-0-2 1-1-0-2 1-0-2-2

BIO-IHBT-3-311

1-0-0-1

BIO- IHBT-3-312 BIO-IHBT-3-313 BIO-IHBT-3-314 BIO-IHBT-3-315 BIO-IHBT-3-316 BIO-IHBT-3-317 BIO-IHBT-3-318 BIO-IHBT-3-319 BIO-IHBT-3-320 BIO-IHBT-3-321

Plant Viruses as Expression Vectors for Vaccines, Gene Silencing, Drug Delivery Vehicle Dietary Supplements Advances in Phytogenetic Remodeling Special Tech for Phytogenetic Remodeling Biometrical Appro to Phytogenetic Remodeling Fungal Pathogenesis in Plants Viral Pathogenesis in Plants Advances in protected cultivation of flower crops Crop Protection Epigenetics and Chromatin Organization Crop Modeling and System Research

BIO-IICB-3-346 BIO-IICB-3-347

Genomics Eukaryotic Gene Regulatory Mechanisms

2-0-0-2 2-0-0-2

BIO-IICB-3-348 BIO-IICB-3-349 BIO-IICB-3-350

Chemical Biology Synthetic and Systems Biology Understanding Glycan structure & their role in Chemical Biology

1-0-0-1 2-0-0-2 2-0-0-2

BIO-IICB-3-351

Modern Drug Discovery & Design

2-0-0-2

BIO-IICT-369 BIO-IICT-370 BIO-IICT-371 BIO-IICT-372

Advanced Pharmacology Disease Mechanisms Industrial/Applied microbiology Protein science and structural based drug design and development

1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1

BIO-IIIM-3-381

Pharmacological screening, Hit identification and mechanism of action ADME Toxicology

1-0-0-1

BIO-IIIM-3-382 BIO-IIIM-3-383

Final Draft

1-0-0-1 2-0-0-2 1-0-0-1 1-0-0-1 2-0-0-2 2-0-0-2 1-0-0-1 1-0-0-1 1-0-2-2

BIO-IITR-3-416 BIO-IITR-3-417 BIO-IITR-3-418 BIO-IITR-3-419 BIO-IITR-3-420 BIO-IITR-3-421 BIO-IITR-3-422

Model systems in Toxicological Research Food & Chemical Toxicology Target organ toxicity Nanomaterial Toxicology Chemical Carcinogenesis and Chemoprevention Neurotoxicology Genes and Environmental Disease

1-0-0-1 2-0-0-2 2-0-0-2 1-0-2-2 1-0-0-1 2-0-0-2 1-0-0-1

BIO-IMT-3-451 BIO-IMT-3-452 BIO-IMT-3-453

Mycobacterium tuberculosis Metagenomics Advanced Biochemical Engineering

2-0-0-2 1-0-0-1 1-0-0-1

BIO-NBRI-3-486 BIO-NBRI-3-487 BIO-NBRI-3-488 BIO-NBRI-3-489 BIO-NBRI-3-490 BIO-NBRI-3-491 BIO-NBRI-3-492

Climate change and Plants Bioremediation Environmental Biochem and Biotech Taxonomy and speciation Plant Conservation and Reproductive Biology Economic Plants and Pharmacology Floriculture and Agronomy

1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1 1-0-0-1

BIO-NCL-3-521

Molecular recognition and molecular interactions in structural biology Advances in Microbiology and Microbial Technology Applications in Plant Biotechnology Beyond Genomes: Concepts in comparative and functional genomics Chemistry & Biology of Heterocycles

4-0-0-4

Microbial Biotechnology Advances in physiological and molecular responses to abiotic stress Biodiversity and conservation Eco-restoration Ethnobotany and Traditional Knowledge Plant - Insect Interaction and Herbivore Managements Advances in Plant Microbes Interactions Advance Plant Physiology Insect Biotechnology Molecular and cell biology Molecular Markers and Breeding Functional Genomics Plant Biotechnology Management and Regulatory Issues

1-0-0-1 1-0-0-1

Bioprocess Technology

2-0-0-2 2-0-0-2

BIO-NCL-3-522 BIO-NCL-3-523 BIO-NCL-3-524 BIO-NCL-3-525

BIO-NEIST-3-591 BIO-NEIST-3-592 BIO-NEIST-3-593 BIO-NEIST-3-594 BIO-NEIST-3-595 BIO-NEIST-3-596 BIO-NEIST-3-597 BIO-NEIST-3-598 BIO-NEIST-3-599 BIO-NEIST-3-600 BIO-NEIST-3-601 BIO-NEIST-3-602 BIO-NEIST-3-603

BIO-NIIST-381 BIO-NIIST-382 BIO-NIIST-383 BIO-NIIST-384 BIO-NIIST-385 BIO-NIIST-386

BIO-NIIST-387 BIO-NIIST-388 BIO-NIIST-389 BIO-NIIST-390

Final Draft

Enzymology and Enzyme Technology Biodegradable polymers Metabolic Engineering

Natural Product Chemistry Cardiovascular Disease Biology Molecular Biology of Diabetes Environmental Technology Biomass to Fuels Biochemical Engineering

4-0-0-4 4-0-0-4 4-0-0-4 2-0-0-2

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AcSIR biological Sciences Course Material as on May 30, 2012

CCMB 100 level courses Course number

Course content

BIO-CCMB-1001

Biostatistics Summarization of Data: measures of center, dispersion, skewness Dependence of variables: Correlation, linear regression, logistic regression Basic probability distributions: Binomial, Normal, Chi-squares. Estimation of parameters: method of moments, maximum likelihood Testing of hypotheses: (a) parametric tests: t-test, z-test, chi-squares test, ANOVA (b) non-parametric tests: Mann-Whitney, Kruskal Wallis, Kolmogorov-Smirnov

BIO-CCMB-1002

Computation/bioinformatics Computers: Introduction, Evolution and Classification of computers. Fundamentals of computing. Bit and Byte, Introduction to types of Hardware and Software. Components of Computer. Introduction to operating systems. Introduction to Computer Viruses. Network: Introduction. Network structure and architecture, Hierarchical networks, Ethernet and TCP/IP family of protocols, transport protocol design. Types of network, Topologies of network, Router, Switch, Data Communication, Concept of Wireless networking, LAN, WAN, MAN, Security of the network, Fire-walls, Network Applications Information Technology: Concepts of client Server Architecture, Concept of search Engine, Database search engines. Introduction to Internet Introduction to Word, Powerpoint and Excel Introduction to Bioinformatics: History of Bioinformatics, Genome sequencing projects, Human Genome Project, Applications of Bioinformatics. Introduction to databases, Type and kind of databases, Applications and limitations. Literature Search Databases, Nucleic acid and protein databases, Animal and plant databases, Ensembl Genome project TIGR database, Biotechnological databases, Motifs and Pattern Databases, Databases for species identification and classification, Structural databases. Database Retrieval and deposition systems. Web tools and resources for sequence analysis: Pairwise and multiple sequence Alignment, Sequence similarity search: BLAST, Pattern recognition, motif and family prediction, Restriction map analysis, primer design, Gene prediction, Phylogenetic Tree, Protein structure prediction and visualization.

BIO-CCMB-1003

Basic Chemistry Thermodynamics Solutions and Ions Chemical bonding and molecular structure Chemical Kinetics Stereochemistry Introduction to drug discovery (Medicinal chemistry approach) Drug target, discovery and development (forward and reverse approach

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BIO-CCMB-1004

Research Methodology, Communication/ethics/safety Philosophy and structure of scientific thoughts, Objective and Motivation of Research, Meaning of the Research, What constitutes a research topic? How to select a research topic?, Importance of literature review, Selection of appropriate methodology, Collection of data, Interpretation of data, Writing research paper, Paper presentation in scientific conference, Statistical methods, Importance of documentation, Procedure for Hypothesis Testing, Values and Ethical Problems, Criteria of Good Research, Good laboratory practice, Chemical, Radioactive and Biological safety: Possible hazards and precautionary measures; do and don’ts upon exposure Research methodology, communication, ethics, safety Asking the right questions: Originality, Depth, Precision can co-exist Formulating and refining the hypothesis: Those who do not learn from the past are condemned to repeat it Study design: Recognizing and minimizing bias Experiment design: Sometimes less is more and the importance of controls Good lab practices: Record keeping, organizing data, organizing the lab space Data interpretation; objectivity, quantification, double blind studies and necessity of statistics Comunicating your data:writing up your research Comunicating your data: presenting your findings Radiation safety Chemical and Biosafety Intellectual property rights What is ethics, the different interpretations & historical instances of unethical science Case studies: Data fraud/ plagiarism and Human Ethics violation

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200 level courses Course number

Course content

BIO-CCMB-2001

Biotechniques and Instrumentation (compulsory) i. General Instrumentation: handling, care, usage and safety (this spectrophotomers, rotors, cuvettes, etc). ii. UV spectroscopy: stead-state and time-resolved fluorescence spectroscopy iii. Vibrational spectroscopy: basic principles and applications in biology iv. Magnetic resonance spectroscopy v. Atomic force microscopy vi. Confocal and fluorescence microscopy vii. Analytical ultracentrifuge viii. Calorimetry (isothermal titration and differential scanning calorimtry) ix. Surface Plasmon Resonance x. Chromatography

BIO-CCMB-2002

includes

Biology of Macromolecules Introduction to biological Macromolecules, The need for polymeric macromolecules for the living cell, Information content (general ideas on Shannon’s information theory), Non-covalent forces (electrostatic, hydrophobic, hydrogen bonding, etc.), Properties of water in relation to macromolecular conformation Problem of protein folding, Introduction to protein folding, Levinthal’s paradox and necessity for folding pathways, discussion on folding pathways (framework, hydrophobic collapse, nucleation-condensation-propagation, zigzag puzzle models and experimental evidence in support and against for these models), Current view of protein folding, Folding surface and funnel, Assisted protein folding, Need for assistance in protein folding in vivo, Differences between in vitro and in vivo folding, Discovery of molecular chaperone, classification of chaperone and brief description of functions of GroEL, Methods for investigating protein folding, Fluorescence and circular dichroism, Basic principles and applications Structure-function relationship : why structure?, Overview of different methods of structure determination, Retrieving, visualizing and understanding macromolecular structures, Correlation between structure and function Protein architecture, Organization of protein structure, Supersecondary structural elements, Ramachandran plot, Structure determination by X-ray crystallography, Globular proteins, Identification of folds and classification, Examples of structurefunction relationship Macro-Molecular interactions, Various models of ligand-protein interactions (simple as well as complex binding models), Analysis strategies (Scatchard and Klotz plots), cooperativity in biology and Hill plot, Methodology and principles for estimation of binding stoichiometry; classical (gel filtration, equilibrium dialysis, stopped flow) as well as advanced methods (absorption, CD, fluorescence, NMR, ITC, SPR etc)., Thermodynamics of interaction and principles of ligand design, Protein-protein interactions Enzymes, Enzyme kinetics, Why study enzyme kinetics? Single substrate, bisubstrate reactions, Determination of Km. Enzyme inhibition – Reversible and irreversible inhibition, Competitive, Non-competitive and uncompetitive inhibition. Independent identical and non-identical substrate binding sites on enzymes, allosteric regulation. Reactions on enzymes and rate enhancements, Transient state stabilization, Transition state analogues and catalytic antibodies.

BIO-CCMB-2003

Biology of Inheritance Prokaryotic genetics Mutagenesis, DNA repair, applications of mutagenesis, mechanisms of gene transfer including conjugation & transduction, and Recombination & mapping. Applications and uses of transposable elements, gene regulation, virulence functions

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and horizontal gene transfer. Eukaryotic genetics Mendelian principles; Segregation and linkage; Recombination and mapping; Gene interactions, forward and reverse genetics. Bayesian methods of risk assessment; consanguinity in humans and model genetic systems; chromosome rearrangements and their effects on gene expression in Drosophila and Neurospora.

BIO-CCMB-2004

Biology of Infection Bacterial Pathogenesis (7 Lectures): Introduction to Bacterial Pathogens, Bacterial Virulence Mechanisms, Mycobacterial Pathogenesis Pathogenesis of Parasites (7 Lectures): Introduction to Parasite Biology, Pathogenesis of Malaria Viral Pathogenesis I (7 Lectures), Introduction to Virology , Molecular Mechanisms of Viral Infections Viral Pathogenesis II (7 Lectures): Inflammation Biology, Cellular Invasion by Viruses, Cellular Detection of Pathogens

BIO-CCMB-2005

Genomics: Information flow in Biological Systems Overview of human genome (4 lectures): Nuclear genome (2 lectures), Mitochondrial genome (2 lectures) Genome mapping (4 lectures): Markers and methods for genome mapping (2 lectures), Linkage analysis (1 lecture), Genome-wide association studies (1 lecture) Genome sequencing (5 lectures): Different methods and applications (2 lectures), Human genome project (1 lecture), Next generation sequencing (2 lectures) Molecular Basis of human diseases (6 lectures): Molecular epidemiology (1 lecture), Autosomal (1 lecture), X-linked (1 lecture), Y-linked (1 lecture), Mitochondrial (2 lectures) Molecular Phylogenetics (4 lectures) Methods for phylogenetic analysis (2 lectures): Origin and migration of modern human (1 lecture), Role of India in early human migration (1 lecture) Pharmacogenomics (2 lectures): Genome variation and drug response (1 lecture), Pharmacogenomics: Indian Scnario (1 lecture) DNA profiling (3 lectures): Evolution of DNA fingerprinting technology (2 lectures), DNA fingerprinting in medicolegal and forensic applications (1 lecture)

BIO-CCMB-2006

Protein science and proteomics Experimental aspects of protein characterization with emphasis on techniques currently used b. Approaches to studying protein conformation in solution c. Holistic approach towards proteomics d. Theoretical methods for studying dynamics of proteins

BIO-CCMB-2009

Plant-Microbe Interaction i. Over view – 1 lecture ii. Plant pathogen virulence functions (bacterial, fungal, and viral) – 8 lectures iii. Host-resistance mechanisms (elicitor and effector triggered immunity) – 5 lectures iv. Plant-symbiont interactions (plant interactions with bacteria and fungi) – 10 lectures v. Plant growth promoting rhizobacteria and biocontrol – 3 lectures vi. Summary – 1 lecture

BIO-CCMB-2017

Epigenetics and Chromatin Organization I. Transcription and Gene Expression 10 lectures (1) Details of the process of transcription in eukaryotes Promoter structure and function: the role of cis-regulatory elements that affect gene function locally and globally (1 lecture), The structure, function, and regulation of

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general transcription factors, RNA polymerases (1 lecture), Transcriptional initiation, elongation, and termination (3 lectures) (2) Gene Activation (2 lectures) DNA-protein Interaction, Gene-specific factors: Activators and repressors (3) Post transcriptional processing and regulation (2 lectures) connections between RNA processing and upstream events in transcription, integration of transcriptional and translational response mechanisms to external stimuli (4) Genome-wide approaches (1 lecture): New surprises, Pervasive transcription II. Chromatin organization 3 lectures (1) Nucleosome structure (2) Nucleosome positioning (3) Chromatin Assembly: Nucleosome assembly, Fiber folding III. Epigenetic Regulatory Mechanisms 15 lectures Transcriptional repression/anti-repression mechanisms (1) Chromatin remodeling (1 lecture) (2) Variation in conservation: Histone variants (1 lecture) (3) Histone Code: covalent modifications (4 lectures): Writing and erasing the Histone code, Reading the Histone code, Functional correlates of epigenetic marks (4) Genome-wide studies (1 lecture): Nucleosome landscape of species, Cross-talks between epigenetic markings (5) Cross-talk between transcription and chromatin (1 lecture) (6) Involvement of RNAi and non-coding small RNAs in gene silencing and genome defense (Lectures by AJ Rachel): Small RNAs: History, discovery and RNAi, miRNAs, piRNAs (3 lectures); and Noncoding RNAs (2 lectures) (7) DNA Methylation and Heterochromatinization (2 lectures by AJ Rachel) BIO-CCMB-2022

Stem cells, regeneration and aging Pluripotency- in the context of embryo, adult and reprogramming. Molecular basis of pluripotency, self renewal and nitch, role of epigenetic changes, stem cells in tissue and organ development. Methods in stem cell research- isolation, characterization and maintenance of human and murine stems cells, derivation of induced pluripotent cells, in vitro differentiation towards derivation of specific lineages. Importance of regeneration, model organisms, molecular mechanisms, role of stem cells in regeneration, regeneration in higher vertebrates, tissue engineering and other techniques in regenerative medicine. Apoptosis, programmed cell death, importance of stress and ROS in apoptosis, stem cell theory of ageing, role of telomeres. Stem cells in cancers.

BIO-CCMB-2101

Self organizations in biology (10 lectures): What is so unique about membrane organization ? What holds the membrane together ? The hydrophobic effect Membrane dynamics  the key to membrane function: time scales  how to monitor membrane dynamics: spectroscopic approaches ? Lipid-protein interactions Membrane proteins: receptors and signaling Membrane domains: platforms for organization ? Evolving role of membranes in pathogenecity II.(4 lectures): Lipid structures (2 lectures) Primacy of membranes in biology, chemistry, distribution, crystal structure of lipids Lipid phase transitions (1 lecture) Biological role of phase transitions, fusion. Emergent properties of lipids (1 lecture) Long range order, heterogeneity and membrane shape control

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300 level courses Course number

Course content

BIO-CCMB-3001

Seminar Course (compulsory) History of science with emphasis on Indian contribution: Seminar by students

BIO-CCMB-3007

Nanobiology Nanoparticle synthesis – various methods including bottoms-up and top-down approaches; Property of Band-gap in materials The significance of nano size, multiplexing and multilayering. Optical properties and nanoparticle shape dependence. Tool used for nano-technology Basic principle of different types of tools (such as nano-lithography, TEM, AFM and other x-ray base detections techniques) will be discussed and their relevance to biological system characterization. Application of nano-technology for development of functional materials for biological applications. Different types of interactions at nano-scale will be discussed to understand and modulate biological response by designing nanostructures and functions. In this lecture basics of micro fluidics systems will also be discussed which create new opportunities for the spatial and temporal control of micro environment for biological applications.

BIO-CCMB-3101

Brain and behaviour I. Overview of the Nervous System and functioning of Neurons at structuralanatomical level, cellular level, molecular level; II. Techniques and tools in understanding Brain and Behaviour, at system lev III. Circuitry level approach to understand Brain and Behavio a. Chemosensory circuit (perception of odour and pheromones), b. Reward circuit (Addiction, Depression, anxiety & related Mood Disorders), c. Learning and memory circuit (Cognitive disorders and mental retardation) IV. Environmental perturbations affecting Brain and Behavior Change in environment affects the gene functions, and also brain and behaviour, via epigenetic mechanisms; Environmental perturbations in early stage of life affect circuit development and maturation and have implications to pervasive CNS disorders in adulthood; V. Biology of Neurodegeneration and Repair (Molecular Biology of Adult Neurogenesis, Neural Progenitor or stem cells)

BIO-CCMB-3102

Genome organization I. Overview of genomes, 1 lecture i. The new science of genomics, major questions and potentials (1 lecture) II. Packaging of genome and higher order regulation of gene expression, 9 lectures i. Chromatinization of genome (2 lectures) ii. Structural and functional domains in genome(2 lectures) iii. Structural basis of epigenetic cellular memory (3 lectures) iv. Chromosomal position effect (1 lecture) v. Nuclear architecture and genomic packaging (1 lecture)

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III. High throughput techniques and tools in analysis of genome organization (4 lecture) i. Epigenome mapping (2 lectures) ii. Bioinformatic tools of comparative genomics (2 lecture)

BIO-CCMB-3103

NMR Micro-imaging and Spectroscopy Introduction: Zeeman Interaction, Chemical Shift, Coupling Constants, Relaxation, Nuclear Overhouser Effect, etc. Heteronuclear NMR and Simplification of NMR: Techniques for Improving Sensitivity, Editing in NMR, etc. In Vivo NMR Spectroscopy: Water Suppression, Localization, Outer Volume Suppression, STEAM, etc. Image Construction Using NMR: Slice Selection, Frequency and Phase Encoding, Contrast in MRI: T1, T2, diffusion; functional MRI

BIO-CCMB-3104

Mass spectroscopy in biology a. Historical introduction to mass spectroscopy b. Study of tissues to molecules by mass spectroscopy c. Limitations of mass spectroscopy

BIO-CCMB-3105

Conservation biology Concepts, history, ethics, values and legal foundations Population genetics and biodiversity, threats to biodiversity, conservation genetics Interventions- Genetic management, conservation of populations and ecosystems, habitat management, origin and conservation of genetic diversity in agricultural plants and animals Sustainable development, climate change and conservation of biodiversity, economics of conservation

BIO-CCMB-3106

Drug Discovery Journey of a drug from discovery to use Target identification and validation Assay development and screening methodologies Designing small molecule compounds (computational tools and mechanism-based) Moving from in vitro to in vivo testing: toxicity and bioavailability

Final Draft

CDRI 100 level courses Course number

Course content

BIO-CDRI-1001

Biostatistics Summarization of Data: measures of center, dispersion, skewness Dependence of variables: Correlation, linear regression, logistic regression Basic probability distributions: Binomial, Normal, Chi-squares. Estimation of parameters: method of moments, maximum likelihood Testing of hypotheses: (a) parametric tests: t-test, z-test, chi-squares test, ANOVA (b) non-parametric tests: Mann-Whitney, Kruskal Wallis, Kolmogorov-Smirnov

BIO-CDRI-1002

Computation/bioinformatics Computers: Introduction, Evolution and Classification of computers. Fundamentals of computing. Bit and Byte, Introduction to types of Hardware and Software. Components of Computer. Introduction to operating systems. Introduction to Computer Viruses. Network: Introduction. Network structure and architecture, Hierarchical networks, Ethernet and TCP/IP family of protocols, transport protocol design. Types of network, Topologies of network, Router, Switch, Data Communication, Concept of Wireless networking, LAN, WAN, MAN, Security of the network, Fire-walls, Network Applications Information Technology: Concepts of client Server Architecture, Concept of search Engine, Database search engines. Introduction to Internet Introduction to Word, Powerpoint and Excel Introduction to Bioinformatics: History of Bioinformatics, Genome sequencing projects, Human Genome Project, Applications of Bioinformatics. Introduction to databases, Type and kind of databases, Applications and limitations. Literature Search Databases, Nucleic acid and protein databases, Animal and plant databases, Ensembl Genome project TIGR database, Biotechnological databases, Motifs and Pattern Databases, Databases for species identification and classification, Structural databases. Database Retrieval and deposition systems. Web tools and resources for sequence analysis: Pairwise and multiple sequence Alignment, Sequence similarity search: BLAST, Pattern recognition, motif and family prediction, Restriction map analysis, primer design, Gene prediction, Phylogenetic Tree, Protein structure prediction and visualization.

BIO-CDRI-1003

Basic Chemistry Thermodynamics Solutions and Ions Chemical bonding and molecular structure Chemical Kinetics Stereochemistry Introduction to drug discovery (Medicinal chemistry approach) Drug target, discovery and development (forward and reverse approach

BIO-CDRI-1004

Research Methodology, Communication/ethics/safety Philosophy and structure of scientific thoughts, Objective and Motivation of Research,

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Meaning of the Research, What constitutes a research topic? How to select a research topic?, Importance of literature review, Selection of appropriate methodology, Collection of data, Interpretation of data, Writing research paper, Paper presentation in scientific conference, Statistical methods, Importance of documentation, Procedure for Hypothesis Testing, Values and Ethical Problems, Criteria of Good Research, Good laboratory practice, Chemical, Radioactive and Biological safety: Possible hazards and precautionary measures; do and don’ts upon exposure Research methodology, communication, ethics, safety Asking the right questions: Originality, Depth, Precision can co-exist Formulating and refining the hypothesis: Those who do not learn from the past are condemned to repeat it Study design: Recognizing and minimizing bias Experiment design: Sometimes less is more and the importance of controls Good lab practices: Record keeping, organizing data, organizing the lab space Data interpretation; objectivity, quantification, double blind studies and necessity of statistics Comunicating your data:writing up your research Comunicating your data: presenting your findings Radiation safety Chemical and Biosafety Intellectual property rights What is ethics, the different interpretations & historical instances of unethical science Case studies: Data fraud/ plagiarism and Human Ethics violation

Final Draft

200 level courses Course number

Course content

BIO-CDRI-2001

Biotechniques and Instrumentation (compulsory) Immuno-techniques: ELISA, Immuno-fluorescence, Immuno-histochemistry, immuno-precipitation, ChIP, etc. Automation in Drug Discovery: High-Content and High-Throughput Screening High resolution microscopy Transmission and Scanning Electron Microscopy and Laser Scanning Confocal Microscopy. Gene Expression Analyses DNA Microarray and Proteomics Radiation biology Introduction to radiation biology, Scintillation counting, Autoradiography. Instrumentation Centrifugation, Transmission Electron Microscope, Scanning Electron Microscope, Laser Scanning Confocal Microscope, High Content Screening System, MALDI-MS.

BIO-CDRI-2002

Biology of Macromolecules Introduction to Primary and secondary structures of proteins and nucleic acids; hydrogen bonding, ionic and hydrophobic interactions. Optical spectroscopy: Photons, chromophores, transition dipole moments, absorbance. Circular Dichroism, Fluorescence and surface plasmon resonance. Particles in a field: Applications of MS for complex proteins, electrophoresis and sedimentation. X-ray diffraction: Overview of theory. Scattering from a periodic lattice, reciprocal space, and symmetry. Phase problem, Patterson functions, molecular replacement, model building and refinement. Nuclear magnetic resonance: overview and practical aspects. Nuclear spin and coupling interactions, multi-dimensional experiments, determination of protein and nucleic acid structures, protein folding, dynamics, SAR by NMR. Cryo-EM: Applications of Cryo-EM on the architecture of molecular machines, organels and organisms. Bioinformatics: 3D structure modeling, visualization softwares, homology modeling, similarity searches, sequence alignment.

BIO-CDRI-2004

Biology of Infection Bacterial (Tuberculosis):Overview of mycobacteria Organization of mycobacterial cell wall and its biosynthesis. Organization of mycobacterial genomes, plasmids and transposons. Mycobacterial infection and pathogenesis. Host response to mycobacterial infection (Immune response). Lab work: Mycobacterial staining, growth analysis, antibiotic tolerance. Virology: Introduction to Viruses (different types of viruses). Basics of Virus-host interaction. Progression of Viruses (viral DNA replication and gene expression). Host response to viral infection (anti-viral immunity). Drugs against viral infection. Lab work: in vitro viral infection. Parasite Biology: Malaria, Leishmania, Filaria Parasite interactions in vector and human host Pathogenesis Immune response to parasitic infection Diagnosis, Treatment and prophylaxis Drug targets and drug resistance

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BIO-CDRI-2006

Protein Science and Proteomics Amino Acids and Proteins Peptide backbone, side chains, polarity, Absorbance, Single letter codes etc. Protein Structure Primary, secondary, tertiary and quaternary structure, covalent modifications of the polypeptide chain, Forces that determine protein structure, Structural motifs in regulatory proteins: DNA-binding proteins, Zinc finger motif, Helix T urn Helix motif Basic Leucine Zipper motifs. Tools: Databank of protein sequences (SWISS-PROT), Basics of protein sequence alignment Protein Regulation Enzymes I: Mechanism of Catalysis Enzymes II: Kinetics & Regulation Protein Methods: Protein separation and purification Methods Protein Function Analysis The Life Cycle of a Protein: Folding to Destruction (Proteasomes and unbiquitination) Practical Training to protein separation/detection using Western blotting Introduction to Proteomics and its advantages over genomics 1D and 2D Gel Electrophoresis: pI, Isoelectric focussing, 2 dimensional gel Gel Staining methods and analysis Protein spot/Band processing for Mass spectrometric analysis Introduction to Mass spectrometers such as MALDI-TOF/TOF and electrospray mass spectrometer. Spectral Peak Annotation and Database search Shotgun Proteomics Protein quantification using Mass spectrometry: ITRAQ, ICAT and SILAC Practical Training for 1D and 2 D gel electrophoresis and subsequent Mass Spectrometric analysis of processed protein spot using MALDI-TOF/TOF

BIO-CDRI-2008

Xenobiotic Interaction and Response Principles of Xenobiotic interactions Overview of various classes of xenobiotics Introduction to Regulatory Toxicology /Guidelines for Regulatory Toxicology Strategies for Toxicological evaluation of xenobiotics Organ specific histopathological response to xenobiotics Systemic effects of xenobiotic action (Hematology) Systemic effects of xenobiotic action (Neurotoxicology) Systemic effects of xenobiotic action (Immunotoxicology) Systemic effects of xenobiotic action (Genotoxicity) Systemic effects of xenobiotic action (Reproductive Toxicology) Systemic effects of xenobiotic action (Hepatotoxicity) Toxicokinetics Molecular Toxicology Biochemical mechanisms of xenobiotic action Computational Toxicology Xenobiotics of environmental origin and their effects Experimental systems in toxicology research: in vitro and in vivo Alternative systems in Toxicology Safe and responsible conduct of toxicology research

BIO-CDRI-2011

Molecular Therapeutics Roadmap to New Drug Discovery and Development Drugs from Nature Molecular Mechanisms of Drug Action Adverse Drug Reactions Safety Pharmacology

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Molecular Pharmacokinetics of therapeutic agents Drug Absorption/Molecular permeability of therapeutic agents Pharmacogenomics and pharmacogenetics in therapeutic efficacy and molecular metabolism Molecular basis of drug interactions Targeted and controlled drug delivery system Laboratory Work

BIO-CDRI-2012

Cell Signaling Principles of Cell Signalling and Biological Consequences Introduction: Overview of Pathways and Networks and GPCR Signalling G Protein–Coupled Receptors G Protein Effectors Ligand-Gated Ion Channels Regulation of Ion Channels by G Proteins Protein Kinases Protein Phosphatases Ras-MAPK Pathways Growth Factor and Receptor Tyrosine Kinases Cytokine Receptors and Jak-STAT Signaling Nuclear Transactivators and Repressors Nuclear Receptors Chromatin Remodeling Regulation of Complexes by Cytoskeletal Elements: Integrins as Force Transducers Linking Mechanical Stimuli and Biochemical Signals Apoptosis MicroRNA

BIO-CDRI-2013

Chemical Biology Chemistry and life: Science at the Interface Chemistry-Biology Introduction to Chemical Biology : This lecture will provide a survey of major topics, technologies, and themes in Chemical Biology RNA interference: Including lectures on RNAi biological applications, siRNA- A tool in chemical biology and designing and synthesizing siRNAs Click Chemistry applications in Chemical Biology Fluorescent probes and fluorescent sensors for studying the biology Chemical Genetics: amelioration of biology through chemistry Semisynthesis of proteins and Protein ligation, native chemical ligation Unnatural amino acids as probes of protein structure and function

BIO-CDRI-2017

Epigenetics and Chromatin Organization Nuclear ultrastructure, chromatin network and spatial organization in the nucleus DNA Replication (Origin recognition and initiation of DNA replication, mechanisms of replication, analyzing DNA replication origins and mechanisms) Transcriptional regulation (The transcription initiation complex: components, transcription factor, recruitment and regulation, regulatory DNA elements) Chromatin organization in prokaryotes and eukaryotes, chromatin assembly/disassembly and transcriptional control, epigenetic control of cancer Protein translation, post-translational modifications, retrotransport Organelle targeting and cellular transport of proteins Transport across membranes and signal transduction Ligand receptors, ion channels, signal transduction pathways

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Calcium signaling Molecular and cellular evolution Abiogenesis, mechanisms of evolution (random mutation, natural selection, genetic drift, endosymbiosis and current controversies Cell cycle regulation and apoptosis Maintenance and transition of the phases of the cell cycle, pathways of programmed cell death Molecular processes in development Gradients and cascades in embryo development BIO-CDRI-2018

Homeostasis and feedback in biological systems Levels of organization: Molecular, Cellular and Tissue Physiology Control and Regulation: Nervous and Endocrine Systems Overview of physiological adaptation Components of homeostasis & physiological feedback Regulation of homeostasis and adaptive mechanisms of glucose, water, pressure & volume, mineral & ion, acid-base (include oxygen-CO2 regulation), temperature Pathways affecting homeostasis Physiological Applications: Reproductive System and contraception

BIO-CDRI-2020

Molecular and Cellular Mechanisms of Defence Cells and tissues of the immune system Innate immunity Effectors of adaptive immunity Antigen and antibody Complement system and inflammatory reaction Major Histocompatibility Complex Antigen processing, presentation Cytokines, chemokines and leukocyte trafficking Immunobiology of the pulmonary system Immune tolerance and autoimmunity Immunobiology and pathology of Malaria Immunobiology and pathology of Leishmania Immunobiology and pathology of Filaria Tumor immunology Transplantation immunology Vaccines

BIO-CDRI-2136

Dosage Form Design Pre-formulation studies Formulation development of Tablets using different excipients, technology involved to develop different types of tablets. Problems associated with production of tablets and its evaluation parameters. Tablet coating Introduction to capsules, different size of capsules, excipient selection, different types of capsules, quality control parameters Sterile Products and admixtures: Development of injectable preparations, small volume and large volume parenterals, excipients used, Quality control parameters Solubilization: Solubility of drugs, drug solubilization in surfactant systems, different techniques for solubilization, hydrotropic solubilization etc. Poly-disperse systems: Development of suspension and emulsions. Stability issues, implications of particle size on stability and its quality control parameters Aerosols: Preparation, characterization and applications

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300 level courses Course number

Course content

BIO-CDRI-3001

Seminar Course (compulsory) History of science with emphasis on Indian contribution Seminar by students

BIO-CDRI-3002

Cancer Biology Cancer: The nature of cancer and class organization Hall Marks of Cancer: Evasion of Apoptosis, Limitless replicative potential, Sustained Angiogenesis, Inflammation Cancer: The Key Players (Carcinogens, tumor virology, oncogenes tumor suppressor genes, cell cycle regulation ) Hypoxia and Angiogenesis in cancer Metabolism and cancer MicroRNAs and cancer Stem Cells and Cancer Chemoresistance & Radioresistance in Cancer Experimental approaches to understanding the origins, diagnosis, and treatment of cancer. Recent advances in the field and future prospects

BIO-CDRI-3006

Microbial Pathogenesis Clinical spectrum of AIDS, Dengue, Tuberculosis, Malaria & Kala-azar (Lectures in reference to Clinical symptoms, Diagnosis, Prophylaxis and Treatments) Cellular and Host tropisms of Organisms and Pathological changes (Lectures in reference to molecular bases of survival of the organisms in the hosts) Metabolic and Enzymatic Pathways (Lectures based on the molecules involved in virulence, diagnosis and drug targets) Mechanism of Actions of Drugs and Drug Resistance (Lectures highlighting present drugs, SDR, MDR, XDR and role of Hosts) Delineations of Genomes and Proteomes of HIV, Plasmodium, L. donovani and M. tuberculosis (Lectures based on Identification of important molecules involved in patho-biology of organisms, future drugs and Immunogens) Laboratory Work: Culture of micro-organisms in laboratory and Infections in vivo and in ex vivo

BIO-CDRI-3008

Neurobiology Introduction- Nervous System Anatomy of Neuron Physiology of Neuron –generation and propagation of AP Neuronal supportive cells – Glial cells Organization of CNS- Brain & Spinal Cord Neurotransmission Neuronal Synapse Neurotransmitters & Receptor Central Neurotransmitters Catecholamines (Epinephrine, Norepineprine & Dopamine) Acetylcholine 5-Hydroxytrytamine (5-HT) Histamine

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Inhibitory Amino Acid (GABA, Glycine & Benzodiazepines) Excitatory Amino Acid (Glutamate) Neuropeptides Endogenous Opioid System Autonomic Nervous System Sensory –Motor Reflexes Neurotransmitters & Diseases Neurotransmitter Mechanisms & Drug Design Experiments (In rodents): Recording of Gross behavior activities, Evaluation of Neuromuscular co-ordination & sensory reflexes BIO-CDRI-3136

Transcription and Gene Regulation Molecular Basis of transcription (RNA Polymerases and mechanism of transcription, positive and negative control of transcription, post transcriptional processing, CTD phosphorylation and function) Chromatin dynamics in gene regulation (DNA methylation, histone variants, nucleosome positioning, histone code, chromatin r Integration of transcription to translation, protein degradation Histone modification and signal transduction

BIO-CDRI-3137

Biol and Therapeutics of Life Style Disorders Concept and introduction to the subject Introduction to disorders affecting central nervous system (pathophysiology and therapeutics) Introduction to disorders affecting cardiovascular system (pathophysiology and therapeutics) Biology of Inflammation and inflammatory disorders (pathophysiology and therapeutics) Pathophysiology and therapeutics of ulcers Energy metabolism and diabetes (pathophysiology and therapeutics) Obesity and syndrome X (pathophysiology and therapeutics) Laboratory work (in vitro and in vivo experiments)

BIO-CDRI-3138

Animal Models in Biomedical Research Introduction to model systems, Origins of Animal Experimentations Laws, regulations and policies affecting the use of Laboratory animals Brief account of biology and diseases of commonly used Rodent models (Mouse, Rat, Hamster, Guinea pigs, Gerbils and Mastomys) Brief account of biology and diseases of different Non-Rodent models (Rabbit, Dog, nonhuman primates) Laboratory Animal Biosecurity (Prevention, containing and eradication) Planning and Execution of Animal Experiments Common Zoonotic Diseases and Prevention. Genetic manipulations and Transgenesis: Principles and methods. Transgenic and Knockout Models for specific diseases. Genetic Monitoring of Experimental Animals. Alternative Models (cell based, Yeast, Drosophila, C. elegans, Zebrafish), advantages and disadvantages. Animal handling, care and Laboratory animal Techniques (practicals).

BIO-CDRI-3139

Pharmacokinetics and metabolism Introduction; Pharmacokinetics and its role in drug discovery and development; Drug absorption, distribution, metabolism and excretion; routes of drug administration; Plasma drug concentration time profile, Pharmacokinetic parameters Bioanalysis tools and techniques; Method development and validation; Regulatory considerations for pharmacokinetic and metabolic data for pre-clinical (e.g. IND) and clinical (e.g. NDA and ANDA) submissions.

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Bioavailability introduction; measurement of bioavailability; Biopharmaceutics classification system; Methods for enhancement of bioavailability. Absorption of Drugs; Mechanisms of drug absorption. Permeability/absorption models, Factors influencing absorption and bioavailability. Distribution of Drugs; Volume of distribution; Factors determining the distribution of drugs: perfusion, molecular size, solubility, protein binding; Significance of drug uptake by the lung; Binding of drug to tissue components. Drug Metabolism and its role in drug discovery and development; Drug metabolizing organs and enzymes. Reaction Phenotyping; Metabolite identification Phase I and Phase II metabolic reactions. Tools and Techniques for studying drug metabolism; Factors affecting metabolism. Pharmacogenetics and Pharmacogenomics; Reactive metabolites and metabolic toxicity; Metabolites in safety testing- need and criterions. Excretion of drugs-basic considerations; Renal and non-renal excretion of drugs. Clearance; Renal function, renal failure and dose adjustment in renal failure. Non-linear Pharmacokinetics; Causes of non-linearity; Michaelis Menten Equation Chronopharmacokinetics, Pharmacokinetic variations in paediatric, geriatric and obese populations Applications of pharmacokinetic principle: Design of dosage regimens, Individualization and Therapeutic Drug Monitoring (TDM). High Throughput approaches in pharmacokinetics and drug metabolism; Applications of computational/predictive tools in pharmacokinetics and drug metabolism; Drugdrug/Food-drug/herb-drug pharmacokinetic interaction studies. BIO-CDRI-3140

Approaches to Drug Delivery Conventional dosage forms- for per-oral and parenteral drug delivery Analytical approaches and method development for pharmaceutical analysis Storage stability under ICH and Schedule Y regimes Controlled release- Principles and strategies Oral controlled release systems Targeted drug delivery with special reference to colloidal particles. Cutaneous and Transdermal drug delivery Delivery of drugs by Pulmonary route Microparticles and nanoparticles for drug delivery Strategies for the delivery of biomacromolecules. Liposomes as drug delivery vehicles BCS system and applications of microemulsions for delivery of poorly soluble drugs. Laboratory Work Matrix-controlled release tablet Adhesive-dispersion transdermal Drug powder for inhalation Development of nanosuspension

BIO-CDRI-3141

An Intro to Drug Discovery & Development Drug Discovery Approaches: Observation-based/Physiology-based (Phenotype),Targetbased approach to drug discovery Areas of interest in drug discovery “Me Too” drugs, New chemical entities, Generics, Pro-drugs, Orphan drugs Milestones in Drug Discovery Technologies impacting each milestone Serendipity/Repositioning Target discovery/validation/druggability/introduction to proteomics and genomics Assay Development—in Vitro/Cell-based/in vivo Biological screening glossary Characteristics of hit/lead Screening techniques: HTS, NMR, X-ray, Virtual Sources of chemical libraries for screening/selection of molecules, natural products/privileged structure Target oriented and Diversity oriented synthesis Biologics Toxicity/PK studies/Formulation Bioinformatics in drug discovery

Final Draft

IPR: IND/NDA Clinical trials Phase I/II/III

Final Draft

CFTRI 100 level courses Course number

Course content

BIO-CFRTI-1001

Biostatistics Summarization of Data: measures of center, dispersion, skewness Dependence of variables: Correlation, linear regression, logistic regression Basic probability distributions: Binomial, Normal, Chi-squares. Estimation of parameters: method of moments, maximum likelihood Testing of hypotheses: (a) parametric tests: t-test, z-test, chi-squares test, ANOVA (b) non-parametric tests: Mann-Whitney, Kruskal Wallis, Kolmogorov-Smirnov

BIO-CFTRI-1002

Computation/bioinformatics Computers: Introduction, Evolution and Classification of computers. Fundamentals of computing. Bit and Byte, Introduction to types of Hardware and Software. Components of Computer. Introduction to operating systems. Introduction to Computer Viruses. Network: Introduction. Network structure and architecture, Hierarchical networks, Ethernet and TCP/IP family of protocols, transport protocol design. Types of network, Topologies of network, Router, Switch, Data Communication, Concept of Wireless networking, LAN, WAN, MAN, Security of the network, Fire-walls, Network Applications Information Technology: Concepts of client Server Architecture, Concept of search Engine, Database search engines. Introduction to Internet Introduction to Word, Powerpoint and Excel Introduction to Bioinformatics: History of Bioinformatics, Genome sequencing projects, Human Genome Project, Applications of Bioinformatics. Introduction to databases, Type and kind of databases, Applications and limitations. Literature Search Databases, Nucleic acid and protein databases, Animal and plant databases, Ensembl Genome project TIGR database, Biotechnological databases, Motifs and Pattern Databases, Databases for species identification and classification, Structural databases. Database Retrieval and deposition systems. Web tools and resources for sequence analysis: Pairwise and multiple sequence Alignment, Sequence similarity search: BLAST, Pattern recognition, motif and family prediction, Restriction map analysis, primer design, Gene prediction, Phylogenetic Tree, Protein structure prediction and visualization.

BIO-CFTRI-1003

Basic Chemistry Thermodynamics Solutions and Ions Chemical bonding and molecular structure Chemical Kinetics Stereochemistry Introduction to drug discovery (Medicinal chemistry approach) Drug target, discovery and development (forward and reverse approach

BIO-CFTRI-1004

Research Methodology, Communication/ethics/safety Philosophy and structure of scientific thoughts, Objective and Motivation of Research,

Final Draft

Meaning of the Research, What constitutes a research topic? How to select a research topic?, Importance of literature review, Selection of appropriate methodology, Collection of data, Interpretation of data, Writing research paper, Paper presentation in scientific conference, Statistical methods, Importance of documentation, Procedure for Hypothesis Testing, Values and Ethical Problems, Criteria of Good Research, Good laboratory practice, Chemical, Radioactive and Biological safety: Possible hazards and precautionary measures; do and don’ts upon exposure Research methodology, communication, ethics, safety Asking the right questions: Originality, Depth, Precision can co-exist Formulating and refining the hypothesis: Those who do not learn from the past are condemned to repeat it Study design: Recognizing and minimizing bias Experiment design: Sometimes less is more and the importance of controls Good lab practices: Record keeping, organizing data, organizing the lab space Data interpretation; objectivity, quantification, double blind studies and necessity of statistics Comunicating your data:writing up your research Comunicating your data: presenting your findings Radiation safety Chemical and Biosafety Intellectual property rights What is ethics, the different interpretations & historical instances of unethical science Case studies: Data fraud/ plagiarism and Human Ethics violation

Final Draft

200 level courses Course number

Course content

BIO-CFTRI-2171

Instrumental Techniques

Qualitative and quantitative analysis of carbohydrates, proteins, fats, vitamins, minerals and dietary fibre; Spectroscopy – principle and application in analysis of food constituents; Chromatographic methods for separation of proteins and determination of molecular mass and homogeneity; (vii) Isolation and purification of enzymes, assay of enzymes and enzyme kinetics; Elucidation of protein structure by physical chemistry methods; Assessment for biological activities associated with phytochemicals; Structural characterization of potent biomolecules by state-of-theart instrumental methodologies – HPLC, GC/GLC, LC-MS, NMR and others; Animal and cell culture methods for evaluation of biological activities associated with active principles of diversified sources; Chemical and physical tests of packaging materials - migration tests for food grade packaging materials, water vapour and gas transmission rates of packaging materials for food storage; Determination of shelf life of packaged foods; Determination of additives & preservatives in foods and residue analysis in foods; Evaluation of physical and chemical properties of rice and cooking quality of rice; Parboiling of paddy and quality evaluation; Rheological characterization of dough and batter; Sensory profile of food ingredients and products – texture, aroma, flavor, consistency and overall acceptability; Aerobic and anaerobic culture methods for determination of microbial populations; Evaluation of food ingredients and products for microbial safety

BIO-CFTRI-2172

Basics of Food Microbiology

Historical development in microbiology; Developments in microscopy; Morphology, cytology and reproduction of bacteria, yeasts and molds; Microbial growth curve; Physical, chemical and biological factors influencing microbial behaviour; Recombination, Transduction, Transformation and Mutations in bacteria; Microbiology of fruits & vegetables; Cereals & cereal products; Meat & meat products; Poultry & eggs; Fish & fish products and milk & milk products; Major types of spoilage and pathogenic microbes and their characteristics; Foodborne infections and intoxications; Mycotoxins – characteristics, types and causative fungal species

BIO-CFTRI-2173

Significance of Food Preservation

Objectives of food processing; Composition of foods; Degree of perishability of unprocessed foods; Causes of quality deterioration and spoilage of perishable foods; Intermediate moisture foods; Principles and methods of blanching; Test for adequacy of blanching; Conventional methods of preservation – Dehydration, Canning, Freezing, Fermentation, Smoking, Pickling, Chemical preservatives and others; Methods of drying and their application to fruits & vegetables; Procedures and technological applications relating to storage of foods at low, chilling and

Final Draft

freezing temperatures

BIO-CFTRI-2174

Thermal Processing of Foods

Principles and types of retorts; Thermal destruction of microorganisms – Determination of D, z & F0 values; Heat resistance in microorganisms; Cooking, blanching, pasteurization and sterilization of foods; Heat penetration and inoculation pack studies

BIO-CFTRI-2175

Canning of Foods

Basic principles of canning; pH classification of foods; Tin plate containers including coating methods; Can fabrication; Aluminum cans; Canning of fruits & vegetables / meat products

BIO-CFTRI-2176

Controlled and Modified Atmosphere Storage of Foods

Basic principles; Minimally processed fruits & vegetables; Modified atmosphere packaging of selected fruits & vegetables; Controlled atmosphere packaging of selected fruits & vegetables; Quality and safety evaluation of MAP and CAP stored products

BIO-CFTRI-2177

Functional Preservatives

Chemical preservatives as effective antimicrobials and antioxidants; Qualitative evaluation of sulphur dioxide and benzoate in foods; Lactic acid bacteria as preservatives

BIO-CFTRI-2178

Hurdle Technology

Principles and application; Intrinsic and extrinsic factors as effective hurdles; Behaviour of microbial contaminants in food system; Shelf life determination

BIO-CFTRI-2179

Infestation Control and Grain Storage

Principles of food commodity storage; Biology of insect pests; Infestation detection and monitoring methods; Pesticides – Classification and chemistry; Controlled atmosphere for insect control and food protection; Pesticide residues in foods; Pesticides and health hazards

Final Draft

BIO-CFTRI-2180

Animal Products Technology

Raw and processed products of meat, fish and poultry; Abattoir design and slaughter methods; Hygienic meat production and carcass evaluation; Meat tenderization; Meat emulsions, sausages and comminuted meat products; Preparation of meat-based traditional food products – tandoori chicken, kababs, etc.; Quality and safety of animal products

BIO-CFTRI-2181

Spices and Plantation Products

Major constituents in pepper, ginger, chilli and turmeric; Analysis of spice oils and oleoresins; Flavour formulations; Tea – brewing and tasting; Coffee – characteristics, roasting and brewing; Cocoa beans – physical & chemical characteristics and chocolate making

BIO-CFTRI-2182

Microbial Fermentations

Microbial growth phase; Physical, chemical and biological factors influencing microbial survival and growth; Fermentative process – solid state and submerged; Design of working of batch, fed-batch and continuous fermenters; Process optimization (Lab. scale to Pilot scale) for higher yield and quality attributes; Downstream processing and quantitative profile of purified metabolites

Final Draft

300 level courses Course number

Course content

BIO-CFTRI-3001

Seminar in topics of courses listed in level 300

BIO-CFTRI-3171

Technology of Cereals and Pulses

Characteristics of wheat & its milled products – physical, chemical and rheological; Influence of ingredients, processing conditions and additives on quality attributes of bakery products; Physical & chemical characteristics of rice and rice-based processed products; Cooking quality of rice; Parboiling of paddy; Processed products of maize, sorghum and finger millet; Processing of pulses including cooking quality; Oilseeds as source of edible protein and oil; Extraction methods for edible oil – ghanni, expeller and solvent; Processing of oilseeds for protein concentrates and isolates

BIO-CFTRI-3172

Technology of Fruits and Vegetables

Maturity indices in fruits and vegetables; Post-harvest spoilage – microbiological and physiological; wax coating; fruit ripening; Measurement of texture & colour in fruits and vegetables; Canning of fruits and vegetables; Preparation of fruit juices/beverages – RTS, squashes, syrups, lime juice cordial; Tomato-based juice, puree, paste, ketchup and soup; Fruit juice concentrates and powders; Fruit & vegetable-based pickles; Preserves and candies; commercial cold storages and supply chain management

BIO-CFTRI-3173

Food Biotechnology

Basic concepts and food applications; Natural food colours and flavours; Recombinant DNA technology and genetic manipulation; Genetically modified organisms/foods – basic concepts and methods to achieve & identify target genes; Safety and applicability of modified foods and food ingredients; Anti-nutritional factors in cereals and pulses; Biotechnological approaches (enzymes/proteins & effective processing parameters)towards reducing/modifying anti-nutritional factors in foods and food ingredients

BIO-CFTRI-3174

Functional Foods

Definition and applicability; Basis to identify functional components in varied sources; Characterization of bioactives from edible sources with defined functional attributes and elucidation of their structure-function relationship; Benefits of identified functional attributes in food ingredients and prepared foods; Legal requirements and regulations for functional foods; Effect of food processing parameters on defined functional attributes

Final Draft

BIO-CFTRI-3175

Nutraceuticals

Definition, terminologies and scope; Plant, animal (marine & sea foods) and microbial based nutraceuticals and their characteristics; Structure-function relationship of defined & characterized nutraceuticals; Potential nutraceuticals (one or two) and their benefits in selected (two each) fruits, vegetables, pulses, cereals, algae (including marine), herbs, spices, plantation crops, desirable microbes and sea foods; Legal requirements and regulations for nutraceuticals; Effect of food processing parameters on defined nutraceuticals

BIO-CFTRI-3176

Dietary Supplements

Definition, characteristics and scope; Status in selected countries across the globe; Intake of dietary supplements and positive health benefits; Performance and functionality; Interaction with one or more functions of human health; Technological suitability of supplements in food processing; Legal requirements and regulations for usage of dietary supplements

BIO-CFTRI-3177

Convenience and Wellness Foods

Major bioactive constituents in pepper, ginger, chilli and turmeric; Cocoa bean fermentation and cocoa based products; Citrus peel oil, fruit pectin and vinegar; Protein isolates and hydrolysates from pulses (oilseeds) and their biological activities; Millets and minor legumes as potential source of bioactives and nutritionals; Emerging trends – frozen dough and healthy bakery foods; Cured meat products; Fermented (including traditional) meat and fish products; Ready-toprepare (cook) foods based on cereals and legumes; Ready-to-eat shelf stable thermally (retorting) processed foods

BIO-CFTRI-3178

Prebiotics and Probiotics

Microorganisms and human health; Prebiotics – definition, nomenclature and significance; Non-digestible higher polysaccharides; Categories of prebiotics; Interaction between prebiotics and microbiota; Probiotics – definition, nomenclature, selection criteria and attributes; Probiotic microorganisms – lactic acid bacteria, bifidobacteria, yeasts; Protocols for commercial probiotic preparations; Health and therapeutic attributes; Safety of probiotics and food applications; Molecular characterization of benefitical attributes associated with probiotics and prebiotics

BIO-CFTRI-3179

Fermented Foods and Beverages

Lactic, acetic, alcoholic and mixed fermentations; Microbial production of polysaccharides, vitamins, amino acids, colours and flavours with one example for each category of products; Milk-based fermented foods – cheese and fermented milks (including Indian traditional foods); Fermented foods based on cereals &

Final Draft

pulses, meat and vegetables

BIO-CFTRI-3180

Sensory Profiling of Foods

Introduction to sensory perception; Physical and chemical sensory scores – quantitative descriptive analysis; Food flavourings; Taints and off-flavours; Instrumental analysis of food flavours; Texture and colour measurements; Packaging materials and their interactions with food constituents; Instrumental and statistical methods in sensory analysis; Requisites of sensory panel, consumer test ranking and Hedonic data analysis

BIO-CFTRI-3181

Microbial Kinetics

Kinetics of microbial growth and death; Bioreactors for microbial cultures and their metabolites; Scale-up process and requisite equipments and process controls; Optimized parameters in fermentation process – composition & sterilization of nutrient medium, aeration, temperature and other influencing parameters

BIO-CFTRI-3182

Food Safety

Microbial contaminants – spoilage & pathogenic bacteria and fungi; Microbial toxins; Limiting factors for survival/growth of pathogenic and spoilage microorganisms; Other food contaminants – heavy metals and residues of pesticides & antibiotics; Food regulations – national and international; Quality systems in food chain – ISO 9001, 14001, 17025 and 22000

BIO-CFTRI-3183

Food Based Nutritional Significance

Nutrition and human health; Macro- and micro-nutrients in food ingredients; Influence of food processing parameters on the efficacy of nutrients; Nutrition related metabolic disorders; Dietary strategies in health and disease management; Health benefits from plant and animal derived bioactive molecules including spice principles; Food based approach and community nutrition; Recommended dietary intake for nutrients and balanced diets in Indian scenario

BIO-CFTRI-3184

Food Chain Establishment

Food plant management – definition and scope; Food plant design & machineries – Regulatory requirements; Concept of hygiene & sanitation in food plant design; Management and its role in planning and coordination; System analysis – basic principles and methodologies; Market research and promotional avenues; Financial aspects and inventory control; Demand and supply in food industry; Computer applications in food processing sector – database, operating systems, networking and others; Intellectual Property Rights and Patents; Scientific documentation of Research outputs

Final Draft

CIMAP 100 level courses Course number

Course content

BIO-CIMAP-1001

Biostatistics Summarization of Data: measures of center, dispersion, skewness Dependence of variables: Correlation, linear regression, logistic regression Basic probability distributions: Binomial, Normal, Chi-squares. Estimation of parameters: method of moments, maximum likelihood Testing of hypotheses: (a) parametric tests: t-test, z-test, chi-squares test, ANOVA (b) non-parametric tests: Mann-Whitney, Kruskal Wallis, Kolmogorov-Smirnov

BIO-CIMAP-1002

Computation/bioinformatics Computers: Introduction, Evolution and Classification of computers. Fundamentals of computing. Bit and Byte, Introduction to types of Hardware and Software. Components of Computer. Introduction to operating systems. Introduction to Computer Viruses. Network: Introduction. Network structure and architecture, Hierarchical networks, Ethernet and TCP/IP family of protocols, transport protocol design. Types of network, Topologies of network, Router, Switch, Data Communication, Concept of Wireless networking, LAN, WAN, MAN, Security of the network, Fire-walls, Network Applications Information Technology: Concepts of client Server Architecture, Concept of search Engine, Database search engines. Introduction to Internet Introduction to Word, Powerpoint and Excel Introduction to Bioinformatics: History of Bioinformatics, Genome sequencing projects, Human Genome Project, Applications of Bioinformatics. Introduction to databases, Type and kind of databases, Applications and limitations. Literature Search Databases, Nucleic acid and protein databases, Animal and plant databases, Ensembl Genome project TIGR database, Biotechnological databases, Motifs and Pattern Databases, Databases for species identification and classification, Structural databases. Database Retrieval and deposition systems. Web tools and resources for sequence analysis: Pairwise and multiple sequence Alignment, Sequence similarity search: BLAST, Pattern recognition, motif and family prediction, Restriction map analysis, primer design, Gene prediction, Phylogenetic Tree, Protein structure prediction and visualization.

BIO-CIMAP-1003

Basic Chemistry Thermodynamics Solutions and Ions Chemical bonding and molecular structure Chemical Kinetics Stereochemistry Introduction to drug discovery (Medicinal chemistry approach) Drug target, discovery and development (forward and reverse approach

BIO-CIMAP-1004

Research Methodology, Communication/ethics/safety Philosophy and structure of scientific thoughts, Objective and Motivation of Research,

Final Draft

Meaning of the Research, What constitutes a research topic? How to select a research topic?, Importance of literature review, Selection of appropriate methodology, Collection of data, Interpretation of data, Writing research paper, Paper presentation in scientific conference, Statistical methods, Importance of documentation, Procedure for Hypothesis Testing, Values and Ethical Problems, Criteria of Good Research, Good laboratory practice, Chemical, Radioactive and Biological safety: Possible hazards and precautionary measures; do and don’ts upon exposure Research methodology, communication, ethics, safety Asking the right questions: Originality, Depth, Precision can co-exist Formulating and refining the hypothesis: Those who do not learn from the past are condemned to repeat it Study design: Recognizing and minimizing bias Experiment design: Sometimes less is more and the importance of controls Good lab practices: Record keeping, organizing data, organizing the lab space Data interpretation; objectivity, quantification, double blind studies and necessity of statistics Comunicating your data:writing up your research Comunicating your data: presenting your findings Radiation safety Chemical and Biosafety Intellectual property rights What is ethics, the different interpretations & historical instances of unethical science Case studies: Data fraud/ plagiarism and Human Ethics violation

Final Draft

200 level courses Course number

Course content

BIO-CIMAP-2001

Biotechniques and Instrumentation (compulsory) Chromatography, Mass spectrometry and Protein identification, Protein interactions : Isothermal calorimetry, Analytical ultracentrifuge, Surface Plasmon resonance, Fluorescence spectroscopy, FACS, Imaging: Electron microscopy, Confocal microscopy, Atomic force microscopy, Single molecule imaging and structure determination of protein complexes, In vivo imaging, RNA/ DNA quantitation (capillary based methods), DNA and protein microarray, NMR, X-Ray crystallography

BIO-CIMAP-2002

Biology of Macromolecules Basic concept: life forms from prokaryotes to eukaryotes; molecules, building blocks;Water and Buffer systems; Nucleic acids and proteins; Lipids; Sugars; Anabolism and catabolism of building blocks and macromolecules

BIO-CIMAP-2003

Biology of Inheritance Evolution, Mendel's Laws of Inheritance, Chromosome theory of inheritance, Codominance and incomplete dominance; pleiotropism, genotypic interactions, epistasis, mechanism of epistasis; Mitosis and Meiosis in plants, animal and human. Cell cycle and cell division. Linkage and mapping in eukaryotes; FISH / GISH, coincidence and interference. Concept of sex determination and patterns in plants and animals; sex chromosomes; Sex-linked, sex-limited and sex-influenced characters. Extra-nuclear inheritance: determining non-Mendelian Inheritance; maternal effects, cytoplasmic inheritance. Nature and components of variation, heritability and genetic advance, self incompatibility and male sterility system, role of mutations and chromosome modifications, induction of polyploidy and its significance, Genetic consequences of self and cross fertilization, mating systems, apomixes.

BIO-CIMAP-2004

Biology of Infection Introduction to microorganisms, types of infection, development and manifestation, defence against infection, prevention of infections, resistance in infectious organisms.

BIO-CIMAP-2005

Genomics: Information flow in Biological Systems Introduction to genomics; Cloning vectors (plasmids, cosmids, BAC, PAC, YAC) genomes and genes; genome organization; Techniques in genomics; Advance sequencing techniques and their application in genomics; DNA Sequence assembly; Application of genomics tools in genotype designing and drug discovery; Defining the genome: from size to functions; Chloroplast and mitochondrial genomes; Functional genomics and beyond.

BIO-CIMAP-2006

Protein Science and Proteomics Introduction proteomics; Extraction of proteins; Separation of proteins; Organelle proteomics; Protein identification and characterization; Structural proteomics and computational analysis; Protein-protein interactions; Techniques for Proteome research; High throughput proteomic screening for novel bioactive peptides/proteins/enzymes

BIO-CIMAP-2007

Systems Biology Central dogma of life, Concept of genome, transcriptome, proteome and metabolome; Comparasion of genomes/transcriptome/proteomes /metabolomes; Synteny; Gene

Final Draft

expression subsets; Primary and secondary metabolism; Analytical tools for systems biology; Applications in plant research.

BIO-CIMAP-2008

Xenobiotic Interaction and Response Toxicokinetics, general toxicology, phytotoxicology, environmental toxicology, adverse drug reaction, drug safety profiling and regulatory toxicology.

BIO-CIMAP-2009

Plant-Microbe Interaction Plant growth promoting microbes; Microbial bio-inoculants; Nitrogen fixing microorganisms: mechanism of nitrogen fixation; Plant diseases and management, Biological control of pathogens; Role of microbial technology in agriculture.

BIO-CIMAP-2010

Plant Environment Interaction Introduction to environment: classification, components of environment; Ecology and ecosystems; Symbiotic relationships; Plant responses to abiotic & biotic stresses; Plant - soil interactions.

BIO-CIMAP-2011

Molecular Therapeutics General pharmacology, phytopharmacology, drug receptor interactions, in-vitro and invivo bioassays in drug discovery and development

BIO-CIMAP-2015

Crop Protection Major pests of crops; Insect - plant relationship; Principles of insect physiology; Toxicology and pathology; Insecticide resistance and residue monitoring; Biopesticides and integrated pest management.

BIO-CIMAP-2016

Developmental Biology-Plants Development and differentiation in plants: Physiological and biochemical basis; Genetic regulation of spatial and temporal development; Genetic regulation of plant growth and development, gametophyte development, fertilization and seed development, seed germination, seed adaptation in relation to environment; Effect of development on plant secondary metabolism.

BIO-CIMAP-2017

Epigenetics and Chromatin Organization Introduction to epigenetics; Techniques in epigenetics; Epigenetics in plants evolution, adaptation and environmental stress, Chromatin structure; Organization of nucleosome and chromosomes; Molecular aspects of cell division and cell cycle. DNA replication in Prokaryotes and Eukaryotes. RNA transcription and processing; Transcriptional regulation in prokaryotes and eukaryotes; Protein synthesis, protein modifications and secretion; Regulation of protein synthesis; Transposable genetic elements, Types and mechanisms of transposition.

BIO-CIMAP-2021

Molecular Breeding of Plants Introduction and techniques in molecular breeding; Morphological and Molecular markers, QTL analysis; Application of molecular breeding in plants; Development of

Final Draft

mapping populations; Molecular mapping and gene tagging of important traits; Markerassisted selection; Gene pyramiding.

BIO-CIMAP-2024

Bioresources and Bioprospection Phyto-taxonomy principles and fundamentals; Biodiversity: principles, importance and characterization; Threats, conservation and gene banking; Remote sensing and GIS concepts and approaches; Bio prospection: principle, techniques and applications.

BIO-CIMAP-2206

Crop Production Systems Sustainable agriculture: crop growth and yield, adaptation of plants to water variation; Soil fertility and nutrient management; IPNMS system; Precision agriculture; Agroforestry systems; Soil-plant-water relationship; Energy concepts; Physiomorphological behaviour of plants; Isotopes and radiation techniques; Metabolic and hormonal responses; Natural resource management.

BIO-CIMAP-2207

Intellectual Property Management

BIO-CIMAP-2208

Applied and fundamental aspects of In Vitro Plant/Cell/Tissue/ Organ Culture Introduction to Plant Cellular totipotency: Process and mechanism; Differentiation, morphogenesis and Somatic embryogenesis; Haploids: Androgenic and gynogenic; Endosperm culture, triploid production and its applications; Somaclonal variations; Somatic hybridization; In vitro production of commercially useful secondary metabolites; Scale up studies using bioreactors; Biotransformations.

BIO-CIMAP-2209

Crop Modelling and System Research Systems-definition, input-output relationships, crop modelling-static descriptive and explanatory models, modelling techniques, Crop modelling- methods for water and nutrient stress effects, data requirement and limitations, Modelling crop-environment interaction, applications of simulation modelling in environmental impact assessment; Agro and post-harvest technology development and dissemination.

Final Draft

300 level courses Course number

Course content

BIO-CIMAP-3001

Seminar Course (compulsory)

BIO-CIMAP-3003

Cell and Tissue Engineering Transgenic plants: Advances in producing transgenics, selection, identification, molecular analysis for confirmation and applications. Molecular farming: salient achievements and future prospects. Metabolic engineering for pathway modulations: propose and potentials. Agrobacterium as natural genetic engineer; molecular mechanism, controlling factors and advantages.

BIO-CIMAP-3004

Frontiers of Biology: Synthetic Biology Molecular biology of metabolic processes in plants and microbes. Molecular regulators of metabolic pathways. Approaches of engineering metabolic pathways in heterologous systems (plants, microbes and insect cell lines)

BIO-CIMAP-3005

Advanced Bioinformatics Databases and resources in Bioinformatics, Gene expression analysis, Sequence analysis and algorithms, Protein and nucleic acid properties, Taxonomy and phylogeny, Next generation sequencing, Structural Bioinformatics, Molecular modeling and simulations, Comparative and functional genomics, Modelling biological systems, Drug design, Advanced programming and scripting.

BIO-CIMAP-3009

Gene Environment Interaction Recent advances in plant responses to biotic and abiotic stresses. Impact of environmental changes at molecular and cellular levels in plants.

BIO-CIMAP-3010

Advances in Gene Silencing Gene silencing: Mechanism, techniques and applications; Antisense RNA technology, RNAi and VIGS; siRNA & miRNA : Biogenesis, translocations, Methods of isolation, characterization and application.

BIO-CIMAP-3013

Advances in Crop Disease Management Genetic improvement of microbial bio control agents-metabolites, rhizosphere colonization, disease control; Mass multiplication of bio control agents, delivery systems, monitoring, commercial bio pesticides, quality control of bio control agents; Enzyme based formulations-status and problems; Molecular diagnostic methods, pathogen-derived resistance, genetic engineering approaches to develop disease resistant plants; Integrated disease management strategies.

BIO-CIMAP-3014

Integrated Pest Management Trends in the development of Integrated Pest Management in national and international level, IPM Theory and Practice, economic threshold concept and economic consideration, Biological control agents, Integration of different methods of pest management, Cost-benefit ratios, case studies of successful IPM programmes

Final Draft

BIO-CIMAP-3206

Anti microbial agents and drug resistance Classification of antimicrobial agents; mechanism of antimicrobial agents, mechanism of drug resistance, strategies for combating drug resistance

BIO-CIMAP-3207

Drug delivery and Pharmaceutical formulations Introduction to pharmaceutical dosage forms, Conventional methods for drug delivery, Novel Drug Delivery Systems (NDDS)

BIO-CIMAP-3208

In-vitro secondary metabolite production and biotransformation Production of commercially useful secondary metabolites by callus/ cell suspension/ hairy root cultures: induction, kinetics of growth and product formation, optimization of physical/chemical factors, precursor-feeding, permeabilization, elicitation and immobilization for improved product recovery. Scale up studies using bioreactors for commercial production-general principles of bioreactors, design optimizations and downstream processing. Biotransformations using cell/hairy root cultures for generating pharmaceutical lead molecules.

BIO-CIMAP-3209

Plant Pathogenesis Principles and concepts in host-pathogen relationship, recognition concept and infection for pathogens; role of enzymes, toxins, growth regulators in disease development; oxidative burst; phytoalexins, PR proteins, elicitors-defense strategies, signal transduction, systemic acquired resistance and induced systemic resistance, defense genes, hypersensitive reaction, programmed cell death, viral induced gene silencing, Rgene expression and transcription profiling

BIO-CIMAP-3210

Biology & Chemistry of Natural Products Classification of plant metabolites – primary & secondary metabolites; various classes of secondary metabolites – Alkaloids, Terpenoids, Phenylpropanoids and their complexes; extraction procedures for natural products; structure elucidation methods for identification of new compound/NCEs; structural modification of natural products. Bioprospecting natural products.

BIO-CIMAP-3211

Biology of inflammation and diseases Activated innate and adapted immune responses, Pathobiology of inflammation, inflammatory reactions in infectious and non-infectious disease conditions, autoimmune disorders

BIO-CIMAP-3212

Soil and crop management Chemistry of soil fertility, principles and methods of soil and plant analysis, fertilizer and fertilizers use technology, mineral nutrition of plants, manures and fertilizers, development and management and of salt affected and other problematic soils, agrometrology, cropping and farming systems, allelochemicals interaction in plants and soils.

Final Draft

CSMCRI 100 level courses Course number

Course content

BIO-CSMCRI1-001

Biostatistics Summarization of Data: measures of center, dispersion, skewness Dependence of variables: Correlation, linear regression, logistic regression Basic probability distributions: Binomial, Normal, Chi-squares. Estimation of parameters: method of moments, maximum likelihood Testing of hypotheses: (a) parametric tests: t-test, z-test, chi-squares test, ANOVA (b) non-parametric tests: Mann-Whitney, Kruskal Wallis, Kolmogorov-Smirnov

BIO-CSMCRI1-002

Computation/bioinformatics Computers: Introduction, Evolution and Classification of computers. Fundamentals of computing. Bit and Byte, Introduction to types of Hardware and Software. Components of Computer. Introduction to operating systems. Introduction to Computer Viruses. Network: Introduction. Network structure and architecture, Hierarchical networks, Ethernet and TCP/IP family of protocols, transport protocol design. Types of network, Topologies of network, Router, Switch, Data Communication, Concept of Wireless networking, LAN, WAN, MAN, Security of the network, Fire-walls, Network Applications Information Technology: Concepts of client Server Architecture, Concept of search Engine, Database search engines. Introduction to Internet Introduction to Word, Powerpoint and Excel Introduction to Bioinformatics: History of Bioinformatics, Genome sequencing projects, Human Genome Project, Applications of Bioinformatics. Introduction to databases, Type and kind of databases, Applications and limitations. Literature Search Databases, Nucleic acid and protein databases, Animal and plant databases, Ensembl Genome project TIGR database, Biotechnological databases, Motifs and Pattern Databases, Databases for species identification and classification, Structural databases. Database Retrieval and deposition systems. Web tools and resources for sequence analysis: Pairwise and multiple sequence Alignment, Sequence similarity search: BLAST, Pattern recognition, motif and family prediction, Restriction map analysis, primer design, Gene prediction, Phylogenetic Tree, Protein structure prediction and visualization.

BIO-CSMCRI1-003

Basic Chemistry Thermodynamics Solutions and Ions Chemical bonding and molecular structure Chemical Kinetics Stereochemistry Introduction to drug discovery (Medicinal chemistry approach) Drug target, discovery and development (forward and reverse approach

BIO-CSMCRI1-004

Research Methodology, Communication/ethics/safety Philosophy and structure of scientific thoughts, Objective and Motivation of Research,

Final Draft

Meaning of the Research, What constitutes a research topic? How to select a research topic?, Importance of literature review, Selection of appropriate methodology, Collection of data, Interpretation of data, Writing research paper, Paper presentation in scientific conference, Statistical methods, Importance of documentation, Procedure for Hypothesis Testing, Values and Ethical Problems, Criteria of Good Research, Good laboratory practice, Chemical, Radioactive and Biological safety: Possible hazards and precautionary measures; do and don’ts upon exposure Research methodology, communication, ethics, safety Asking the right questions: Originality, Depth, Precision can co-exist Formulating and refining the hypothesis: Those who do not learn from the past are condemned to repeat it Study design: Recognizing and minimizing bias Experiment design: Sometimes less is more and the importance of controls Good lab practices: Record keeping, organizing data, organizing the lab space Data interpretation; objectivity, quantification, double blind studies and necessity of statistics Comunicating your data:writing up your research Comunicating your data: presenting your findings Radiation safety Chemical and Biosafety Intellectual property rights What is ethics, the different interpretations & historical instances of unethical science Case studies: Data fraud/ plagiarism and Human Ethics violation

Final Draft

200 level courses Course number BIO-CSMCRI-2001

Course content Biotechniques and Instrumentation (compulsory) Part-I Chromatographic Analysis: GLC, HPLC, HPTLC and Flash chromatography Part- II- Spectroscopic analysis: UV, AAS and Mass spectrometry Part- III – Microscopy Light Microscopy, Confocal Microscopy, SEM and TEM NMR Spectroscopy in Plant Metabolomics: Introduction & Scope of NMR Spectroscopy and Applications of NMR Spectroscopy in Plant Metabolomics Electrophoresis: agarose and polyacrylamide gel (native and denaturing), 2-D gel Centrifugation (high speed, ultra and differential centrifugation) Common Molecular Biology Techniques Chromatography: affinity, ion exchange, hydrophobic chromatography, size exclusion and reverse phase chromatography Proteomics- MALDI-MS/MS, LC-ESI-MS/MS Practical Chromatography Techniques Spectroscopy Techniques

BIO-CSMCRI-2002

Biology of Macromolecules Structure and function of Cell and Cell organelles, Nucleic acids and proteins; Chromatin structure; Organization of nucleosome and chromosomes; Molecular aspects of cell division and cell cycle; DNA replication in Prokaryotes and Eukaryotes; RNA transcription and processing; Transcriptional regulation in prokaryotes and eukaryotes; Genetic code: Properties and codon usage patterns; Protein synthesis, protein modifications and secretion; Regulation of protein synthesis; Transposable genetic elements, Types and mechanisms of transposition; Chloroplast and Mitochondrial Genome Organization

BIO-CSMCRI-2003

Biology of Inheritance Evolution, Mendel's Laws of Inheritance, Chromosome theory of inheritance, Codominance and incomplete dominance; pleiotropism, genotypic interactions, epistasis, mechanism of epistasis; Mitosis and Meiosis in plants, animal and human. Cell cycle and cell division. Linkage and mapping in eukaryotes; Coincidence and interference. Concept of sex determination and patterns in plants and animals; sex chromosomes; Sex-linked, sex-limited and sex-influenced characters. Extra-nuclear inheritance: determining non-Mendelian Inheritance; maternal effects, cytoplasmic inheritance. Nature and components of variation, heritability and genetic advance, self incompatibility and male sterility system, role of mutations and chromosome modifications, Genetic consequences of self and cross fertilization, mating systems, apomixes.

BIO-CSMCRI-2005

Genomics: Information flow in Biological Systems Introduction to genomics; Techniques in genomics; Advance sequencing techniques and their application in genomics; Application of genomics study in plants

BIO-CSMCRI-2006

Final Draft

Protein Science and Proteomics Introduction proteomics; Extraction of proteins for proteomics analysis; Separation of proteins for proteomics analysis; Organelle proteomics; Protein identification and characterization; Post-translational modifications; Structural proteomics and computational analysis; Protein-protein interactions; Techniques for Proteome research; High throughput proteomic screening for novel bioactive peptides/proteins/enzymes

BIO-CSMCRI-2009

Plant-Microbe Interaction Plant growth promoting bacteria, mycorrhizae, actinorhiza, current advances in microbial bio-inoculants, latest concepts in taxonomy of nitrogen fixing microorganisms, plant growth promoting rhizobacteria, mechanism of nitrogen fixation, molecular basis for legume rhizobia interaction, nitrogen fixation in free living and associative bacteria, actinorhizal symbiosis, role of biotechnology in agriculture Concept, definitions, importance, principles of plant disease management with bioagents, history of biological control, merits and demerits of biological control, types of biological interactions, operational mechanisms and its relevance in biological control, Factors governing biological control of pathogens, comparative approaches to biological control of plant pathogens by resident and introduced antagonists Economic impact of viral and viroid diseases, molecular characteristics, movement through plasmodesmata and vasculature, viral determinants involved in phloem transport of plant viruses

BIO-CSMCRI-2010

Plant Environment Interaction Introduction to environment: classification, components of environment; Ecology and ecosystems; Symbiotic relationship; Introduction to abiotic stress; Plant responses to abiotic stresses; Introduction to biotic stress; Plant responses to biotic stress

BIO-CSMCRI-2019

In Vitro Development and Morphogenesis in Plants Introduction, Production of disease free quality planting materials; Somaclonal variations (concept and applications, visual, molecular and other screening methods); Haploids (anther, ovule culture and bulbosum technique, detection of haploids, applications); Endosperm culture, triploid production and its application; Protoplast culture, somatic hybrids and cybrids, selection strategies and applications; Secondary metabolites, hairy root culture, molecular farming, scale up studies using bioreactors; Ex situ conservation, short and long term storage of germplasm; Applications of tissue culture in commercialization; In vitro methods of crop improvement using transgenic technology and their Implications

BIO-CSMCRI-2021

Molecular Breeding of Plants Introduction to molecular breeding; Techniques in molecular breeding; Morphological and Molecular markers, QTL analysis; Application of molecular breeding in plants., development of mapping populations (F2, Back crosses, Recombinant Inbred Lines , Near Isogenic Lines and Doubled Haploid lines). Molecular mapping and gene tagging of important traits, Marker-assisted selection, Gene pyramiding. Antisense RNA technology. production of transgenic plants; gmos, biosafety issues.

BIO-CSMCRI-2023

Natural Resource Management Sustainable agriculture, Soil fertility and productivity, SOM, Nutrients function, Dynamics of major plant nutrients, nutrient use efficiency, IPNMS system, Precision agriculture, Growth Analysis, Crop response function, Economics of Agroforestry systems

BIO-CSMCRI-2027

Bioresource Production Systems Advances in Soil-plant-water Relationship: Energy concepts, Physio-morphological behaviour of plants, Soil physico-chemical properties, isotopes and radiation techniques, Metabolic and hormonal responses, Water use efficiency, Crop growth and yield, adaptation of plants to water variation

Final Draft

300 level courses Course number

Course Content

BIO-CSMCRI-3001

Seminar Course (compulsory) History of science with emphasis on Indian contribution: Seminar by students on any contemporary topic

BIO-CSMCRI-3005

Advanced Bioinformatics Databases and resources in Bioinformatics, Gene expression analysis, Sequence analysis and algorithms, Next generation sequencing, Non-coding elements, Structural Bioinformatics, Programming and Scripting, Statistics

BIO-CSMCRI-3009

Gene Environment Interaction Recent advances in plant responses to biotic and abiotic stresses. Impact of environmental changes at molecular and cellular levels in plants.

BIO-CSMCRI-3010

Advances in Gene Silencing and Epigenetics Gene silencing: Mechanism of gene silencing in plants, Techniques in gene silencing, Application of gene silencing in plants; Introduction to small RNA; Biogenesis of small RNAs; Translocation of small RNAs in plants; Methods of small RNA isolation and characterization; Application of small RNAs in plants. Mechanism and applications of Epigenetics in plants

BIO-CSMCRI-3011

Microbial Diversity and Habitat Ecology Current developments in microbial taxonomy, phenotypic microarrays, chemotaxonomy, nucleic acid and protein based methods, explorations for yet to be cultured microorganisms, metagenomics approach and recent topics on various groups of microorganisms, basis of adaptation to extreme environments, biotechnological applications of extremophilic microorganisms, industrially important extremophilic enzymes, assignments and discussions

BIO-CIMAP-3014

Integrated Pest Management Trends in the development of Integrated Pest Management in national and international level, IPM Theory and Practice, economic threshold concept and economic consideration, Biological control agents, Integration of different methods of pest management, Cost-benefit ratios, case studies of successful IPM programmes

BIO-CSMCRI-3241

Fermentation Technology

BIO-CSMCRI-3242

Salt tolerance mechanism in plants and Genetic manipulation Gene resources: Salt responsive genes from halophytes; Gene cloning: Subtractive hybridization, RACE; Cloning vectors and their characteristics, Restriction digestion, ligation of DNA molecules; Recombinant selection and confirmation. Transcript profiling under salt stress, isolation of stress inducible promoter and their characterization, Plant transformation: Construction of expression vector, Methods of transformationAgrobacterium mediated and Gene gun. Transgenic analysis: PCR approach, Southern blotting, Northern blotting.

BIO-CSMCRI-3243

Final Draft

Biology of marine macroalgae

The marine environment; Introduction to marine macroalgae, Classification, Molecular systematic & phylogeny and life histories; Seaweed communities and biotic interactions; Physiology: Nutrient uptake, assimilation and growth kinetics; Abiotic stress mechanisms; In vitro culture and micropropagation: media preparation and culture methods; Clonal propagation and selection of strains; Macroalgal diseases, control measures and defense system; Application of biotechnological interventions for genetic improvement; Cultivation of macroalgae; seaweed conservation; Economic importance of macroalgae and their products.

BIO-CSMCRI-3244

Wasteland biology and reclamation Categories of wasteland in India, Land use capability classification, Principles and methods of soil, plant and water analysis, Dynamics of macro and micro-nutrients in soil, Soil fertility and productivity, Soil-plant-water relationship, Response of plants to various environmental stress, Wastelands vegetations, Microbial community structure, Plant-microbe interaction, Biofuel and non-traditional crops for wastelands, Sustainable agriculture and precision farming, Management of saline, sodic and other wastelands, Life cycle assessment for production systems

Final Draft

IGIB 100 level courses Course number

Course Content

BIO-IGIB-1001

Biostatistics Summarization of Data: measures of center, dispersion, skewness Dependence of variables: Correlation, linear regression, logistic regression Basic probability distributions: Binomial, Normal, Chi-squares. Estimation of parameters: method of moments, maximum likelihood Testing of hypotheses: (a) parametric tests: t-test, z-test, chi-squares test, ANOVA (b) non-parametric tests: Mann-Whitney, Kruskal Wallis, Kolmogorov-Smirnov

BIO-IGIB-1002

Computation/bioinformatics Computers: Introduction, Evolution and Classification of computers. Fundamentals of computing. Bit and Byte, Introduction to types of Hardware and Software. Components of Computer. Introduction to operating systems. Introduction to Computer Viruses. Network: Introduction. Network structure and architecture, Hierarchical networks, Ethernet and TCP/IP family of protocols, transport protocol design. Types of network, Topologies of network, Router, Switch, Data Communication, Concept of Wireless networking, LAN, WAN, MAN, Security of the network, Fire-walls, Network Applications Information Technology: Concepts of client Server Architecture, Concept of search Engine, Database search engines. Introduction to Internet Introduction to Word, Powerpoint and Excel Introduction to Bioinformatics: History of Bioinformatics, Genome sequencing projects, Human Genome Project, Applications of Bioinformatics. Introduction to databases, Type and kind of databases, Applications and limitations. Literature Search Databases, Nucleic acid and protein databases, Animal and plant databases, Ensembl Genome project TIGR database, Biotechnological databases, Motifs and Pattern Databases, Databases for species identification and classification, Structural databases. Database Retrieval and deposition systems. Web tools and resources for sequence analysis: Pairwise and multiple sequence Alignment, Sequence similarity search: BLAST, Pattern recognition, motif and family prediction, Restriction map analysis, primer design, Gene prediction, Phylogenetic Tree, Protein structure prediction and visualization.

BIO-IGIB-1003

Basic Chemistry Thermodynamics Solutions and Ions Chemical bonding and molecular structure Chemical Kinetics Stereochemistry Introduction to drug discovery (Medicinal chemistry approach) Drug target, discovery and development (forward and reverse approach

BIO-IGIB-1004

Research Methodology, Communication/ethics/safety Philosophy and structure of scientific thoughts, Objective and Motivation of Research,

Final Draft

Meaning of the Research, What constitutes a research topic? How to select a research topic?, Importance of literature review, Selection of appropriate methodology, Collection of data, Interpretation of data, Writing research paper, Paper presentation in scientific conference, Statistical methods, Importance of documentation, Procedure for Hypothesis Testing, Values and Ethical Problems, Criteria of Good Research, Good laboratory practice, Chemical, Radioactive and Biological safety: Possible hazards and precautionary measures; do and don’ts upon exposure Research methodology, communication, ethics, safety Asking the right questions: Originality, Depth, Precision can co-exist Formulating and refining the hypothesis: Those who do not learn from the past are condemned to repeat it Study design: Recognizing and minimizing bias Experiment design: Sometimes less is more and the importance of controls Good lab practices: Record keeping, organizing data, organizing the lab space Data interpretation; objectivity, quantification, double blind studies and necessity of statistics Comunicating your data:writing up your research Comunicating your data: presenting your findings Radiation safety Chemical and Biosafety Intellectual property rights What is ethics, the different interpretations & historical instances of unethical science Case studies: Data fraud/ plagiarism and Human Ethics violation

Final Draft

200 level courses Course number BIO-IGIB-2005

Course content

Genomics: Information flow in Biological Systems G. K. Chesterton said: "A building is akin to dogma; it is insolent, like dogma. Whether or no it is permanent, it claims permanence, like a dogma. People ask why we have no typical architecture of the modern world, like impressionism in painting. Surely it is obviously because we have not enough dogmas; we cannot bear to see anything in the sky that is solid and enduring, anything in the sky that does not change like the clouds of the sky." Science moves forward by the demolishing of existing dogmas. Nowhere in biology is it more relevant today than our understanding of the genome and its complexity. The course will chart the changes in our understanding and appreciation of the human, and other, genomes. It will attempt to bring forth the latest concepts in dissecting the genome and revealing functional elements of evolutionary and regulatory importance.

BIO-IGIB-2006

Protein Science and Proteomics    

BIO-IGIB-2276

Proteins, sequence-folding relationship, evolution of sequence, silent mutations and folding, diseases of conformation. Structure and conformation, techniques and challenges Dynamic regulation of protein function Why proteomics?, Basic principles, 1D and 2D gel electrophoresis, Differential in gel electrophoresis, Fractionation techniques used in proteomics, Peptide fragmentation, Quantitative proteomics using LC MS approach, Challenges in plasma proteomics

The host and the invaders: the eternal battle The invader: survival stratagies of pathogens, virulence factors, sensing of environment and regulation of virulence gene expression, subversion of host defence mechanisms. The Host: host defence processes, involvement of immune cells and their mediators, abnormalities in host immune system and their implication in disease processes.

BIO-IGIB-2277

The nature of chemical and biological diversity Molecular Diversity and Biosynthetic pathways, Multi-functional Enzymatic assemblies, Coevolution of the chemical and biological world within the organisms

BIO-IGIB-2278

Dynamic nature of biology Dynamic regulation of biological processes enable the cell and in turn the organism to survive a changing environment and thrive. Regulation has multiple layers starting from genome structure to gene expression and function. The mechanisms of regulation and the consequences of breakdown of regulation such as disease and loss of viability will be discussed.

Final Draft

300 level courses Course number

Course content

BIO-IGIB-3276

Playing with Genomes The course will provide hands-on oppurtunity to assemble and annotate a genome.

BIO-IGIB-3277

Complex Disease Genomics     

BIO-IGIB-3278

Death & Disease: the cellular dilemma    

BIO-IGIB-3279

Using the genome to unravel complex diseases Looking for the needles in the haystack: Genome Wide Association Studies (GWAS) The intimate but mysterious relationship between genotype and phenotype Genetic differences & personalized medicine Genetic differences and predictive power

Cellular death, various forms and mechanisms The why and wherefore of death Death as a preventative for disease When death pathways breakdown

The Micro-World     

Microbial diversity Culturable and unculturable bacteria Microbial community structure and dynamics Microbial-Environmental Interactions Human body as a microbial observatory Metagenomics and synthetic biology

BIO-IGIB-3280

Space and Time in Biological Systems The different scales of time in biology How time is defined at the organismal and cellular level How time delays and periodicity is generted in biological systems How do network motifs regulate biological processes

BIO-IGIB-3281

Immortality: the everlasting quest The ability to regenerate lost or damaged organs is a dream humans have had since the beginning of civilization. Although humans have very limited capacity for regeneration, there are a many organisms that can regenerate complete organs and at times their whole body. We will explore these magical organisms and distill what we have learnt from studies of such organisms. The discussion course will try to estimate what our challenges will be if stem cell biology has to meet its expectations. We will discuss the latest advances made in the field of stem cell biology and the extent of our present ability to convert somatic cells into stem cells and then lead them down particular pathways of differentiation. The need to understand development and cellular reprogramming to generate tissues of our

Final Draft

choice from the pluripotent stem cells.

BIO-IGIB-3282

Electronics for Biologists Revolution in electronics has transformed our lives over the last few decades. However, most of the complex electronic systems that we see today are constructed from a few basic electronic components. The aim of the course is two-fold: To explain and demonstrate how complexity arises out of a few basic electronic elements thereby encouraging students to draw parallels between complex biological systems and electronic systems. Secondly, students will learn how to create complex interactive objects and environments such as sensing platforms using open source Arduino microcontrollers. Basic principles of optics will also be introduced as a part of the course and participants will have an opportunity for hands-on exploration of common biological instruments such as microscopes, cell sorters and sequencers. The course has enough flexibility built-in so that students can design their own assignment projects and explore their areas interest.

Final Draft

IHBT 100 level courses Course number

Course Content

BIO-IHBT-1001

Biostatistics Summarization of Data: measures of center, dispersion, skewness Dependence of variables: Correlation, linear regression, logistic regression Basic probability distributions: Binomial, Normal, Chi-squares. Estimation of parameters: method of moments, maximum likelihood Testing of hypotheses: (a) parametric tests: t-test, z-test, chi-squares test, ANOVA (b) non-parametric tests: Mann-Whitney, Kruskal Wallis, Kolmogorov-Smirnov

BIO-IHBT-1002

Computation/bioinformatics Computers: Introduction, Evolution and Classification of computers. Fundamentals of computing. Bit and Byte, Introduction to types of Hardware and Software. Components of Computer. Introduction to operating systems. Introduction to Computer Viruses. Network: Introduction. Network structure and architecture, Hierarchical networks, Ethernet and TCP/IP family of protocols, transport protocol design. Types of network, Topologies of network, Router, Switch, Data Communication, Concept of Wireless networking, LAN, WAN, MAN, Security of the network, Fire-walls, Network Applications Information Technology: Concepts of client Server Architecture, Concept of search Engine, Database search engines. Introduction to Internet Introduction to Word, Powerpoint and Excel Introduction to Bioinformatics: History of Bioinformatics, Genome sequencing projects, Human Genome Project, Applications of Bioinformatics. Introduction to databases, Type and kind of databases, Applications and limitations. Literature Search Databases, Nucleic acid and protein databases, Animal and plant databases, Ensembl Genome project TIGR database, Biotechnological databases, Motifs and Pattern Databases, Databases for species identification and classification, Structural databases. Database Retrieval and deposition systems. Web tools and resources for sequence analysis: Pairwise and multiple sequence Alignment, Sequence similarity search: BLAST, Pattern recognition, motif and family prediction, Restriction map analysis, primer design, Gene prediction, Phylogenetic Tree, Protein structure prediction and visualization.

BIO-IHBT-1003

Basic Chemistry Thermodynamics Solutions and Ions Chemical bonding and molecular structure Chemical Kinetics Stereochemistry Introduction to drug discovery (Medicinal chemistry approach) Drug target, discovery and development (forward and reverse approach

BIO-IHBT-1004

Research Methodology, Communication/ethics/safety Philosophy and structure of scientific thoughts, Objective and Motivation of Research,

Final Draft

Meaning of the Research, What constitutes a research topic? How to select a research topic?, Importance of literature review, Selection of appropriate methodology, Collection of data, Interpretation of data, Writing research paper, Paper presentation in scientific conference, Statistical methods, Importance of documentation, Procedure for Hypothesis Testing, Values and Ethical Problems, Criteria of Good Research, Good laboratory practice, Chemical, Radioactive and Biological safety: Possible hazards and precautionary measures; do and don’ts upon exposure Research methodology, communication, ethics, safety Asking the right questions: Originality, Depth, Precision can co-exist Formulating and refining the hypothesis: Those who do not learn from the past are condemned to repeat it Study design: Recognizing and minimizing bias Experiment design: Sometimes less is more and the importance of controls Good lab practices: Record keeping, organizing data, organizing the lab space Data interpretation; objectivity, quantification, double blind studies and necessity of statistics Comunicating your data:writing up your research Comunicating your data: presenting your findings Radiation safety Chemical and Biosafety Intellectual property rights What is ethics, the different interpretations & historical instances of unethical science Case studies: Data fraud/ plagiarism and Human Ethics violation

Final Draft

200 level courses Course number

Course Content

BIO-IHBT-2001

Biotechniques pH and Buffers in Biology, Chromatography, Electrophoresis, Mass spectrometry, Radioisotopes, Microscopy, Immunotechniques, Gene and genome technologies, Spectroscopy, Protein and proteomics, Techniques in Plant Physiology, Techniques in Microbiology, Techniques in cell and tissue culture

BIO-IHBT-2002

Biology of Macromolecules Structure and function of Cell and Cell organelles, Nucleic acids and proteins; Chromatin structure; Organization of nucleosome and chromosomes; Molecular aspects of cell division and cell cycle; DNA replication in Prokaryotes and Eukaryotes; RNA transcription and processing; Transcriptional regulation in prokaryotes and eukaryotes; Genetic code: Properties and codon usage patterns; Protein synthesis, protein modifications and secretion; Regulation of protein synthesis; Transposable genetic elements, Types and mechanisms of transposition; Chloroplast and Mitochondrial Genome Organization Enzymes, Enzyme kinetics, Why study enzyme kinetics? Single substrate, bisubstrate reactions, Determination of Km. Enzyme inhibition – Reversible and irreversible inhibition, Competitive, Non-competitive and uncompetitive inhibition

BIO-IHBT-2003

Biology of Inheritance Evolution, Mendel's Laws of Inheritance, Chromosome theory of inheritance, Codominance and incomplete dominance; pleiotropism, genotypic interactions, epistasis, mechanism of epistasis; Mitosis and Meiosis in plants, animal and human. Cell cycle and cell division. Linkage and mapping in eukaryotes; Coincidence and interference. Concept of sex determination and patterns in plants and animals; sex chromosomes; Sex-linked, sex-limited and sexinfluenced characters. Extra-nuclear inheritance: determining non-Mendelian Inheritance; maternal effects, cytoplasmic inheritance. Nature and components of variation, heritability and genetic advance, self incompatibility and male sterility system, role of mutations and chromosome modifications, Genetic consequences of self and cross fertilization, mating systems, apomixes.

BIO-IHBT-2004

Biology of Infection Host pathogen interaction Infection and infectious process and routes of transmission, Methods of transmission and role of vectors (Mosquitoes, Sand fly) Description and pathology of bacterial diseases Infections caused by Gram negative and Gram positive bacteria, Tuberculosis, Principles of antibiotic action mechanisms and molecular basis of antibiotic resistance Description and pathology of fungal diseases Infections caused by candida spp, Infections caused by filamentous fungi Description and pathology of parasitic infections e.g. Malaria and Leishmania General properties of viruses Structure and replication of DNA and RNA viruses, Virus-host interactions, Detection and Cultivation of viruses

Final Draft

Description and pathology of viral infections Infections caused by Flavi-viruses, Pox viruses, herpes viruses, myxo and paramyxo viruses, adenoviruses and other respiratory viruses, hepatitis viruses, HIV Biology and pathogenesis involved in Flavi-viruses Immunology Innate and acquired immunity, Components of immune system, T-cell subsets and surface markers, antigen processing and presentation, Antigen-antibody interactions, Types of hypersensitivity reactions, Host response to viral infection (anti-viral immunity), antiviral compounds, Vaccines and vaccinations Techniques in diagnostic microbiology: Immunological techniques, Serological techniques, Nucleic acid techniques, Biological safety in handling pathogenic bacteria and viruses BIO-IHBT-2005

Genomics: Information flow in Biological Systems Introduction to genomics; Cloning vectors (plasmids, cosmids, BAC, PAC, YAC). Genome Organization: Nuclear, Mitochondrial and Chloroplast Genome, Techniques in genomics; Advance sequencing techniques and their application in genomics; Application of genomics study in plants Genome mapping: Markers and methods for genome mapping, Linkage analysis, Genome-wide association studies. Overview of Arabidopsis and rice genome.

BIO-IHBT-2006

Protein Science and Proteomics Amino Acids and Proteins Peptide backbone, side chains, polarity, Absorbance, Single letter codes etc. Protein Structure Primary, secondary, tertiary and quaternary structure, covalent modifications of the polypeptide chain, Forces that determine protein structure, Structural motifs in regulatory proteins: DNA-binding proteins, Zinc finger motif, Helix T urn Helix motif Basic Leucine Zipper motifs. Tools: Databank of protein sequences (SWISS-PROT), Basics of protein sequence alignment Protein Regulation Enzymes I: Mechanism of Catalysis Enzymes II: Kinetics & Regulation Protein Methods: Protein separation and purification Methods Protein Function Analysis The Life Cycle of a Protein: Folding to Destruction (Proteasomes and unbiquitination) Introduction proteomics; Extraction of proteins for proteomics analysis; Separation of proteins for proteomics analysis; Organelle proteomics; Protein identification and characterization; Post-translational modifications; Structural proteomics and computational analysis; Protein-protein interactions; Techniques for Proteome research; High throughput proteomic screening for novel bioactive peptides/proteins/enzymes

BIO-IHBT-2009

Plant-Microbe Interaction Principles and Concepts in Host-Pathogen Relationship, Recognition Concept and Infection for Pathogens and Non-Pathogens, Role of Enzymes, Toxins, Growth Regulators in Disease Development, Oxidative Burst, Phenolics, Phytoalexins, PR Proteins, Elicitors-Defense Strategies, Signal Transduction, Systemic Acquired Resistance and Induced Systemic Resistance Structural Genes, Defense Genes, Hypersensitive Reaction, Reactive Oxygen Species, Phytoalexins, Programmed Cell Death, Viral Induced Gene Silencing, R-Gene Expression and Transcription Profiling, Mapping and Cloning of Resistance Genes and Marker-Aided Selection, Gene Pyramiding.

Final Draft

Economic Impact of Viral and Viroid Diseases, Molecular Characteristics, Movement through Plasmodesmata and Vasculature, Viral Determinants Involved in Phloem Transport of Plant Viruses.

BIO-IHBT-2010

Plant Environment Interaction Introduction to environment: classification, components of environment; Ecology and ecosystems; Phenotypic plasticity and plant adaptation; Introduction to abiotic stress; Plant responses to abiotic stresses; Introduction to biotic stress; Plant responses to biotic stress

BIO-IHBT-2015

Crop Protection Major pests of crops, insect host plant relationship, principles of insect physiology, toxicology and pathology, insecticide resistance and residue monitoring, insect pest management, biopesticides, principals of integrated pest management

BIO-IHBT-2016

Developmental Biology-Plants Introduction to developmental biology of plants, genetic regulation of plant growth and development, gametophyte development, fertilization and seed development, seed germination, seed adaptation in relation to environment

BIO-IHBT-2019

In Vitro Development and Morphogenesis in Plants Introduction, Production of disease free quality planting materials; Somaclonal variations (concept and applications, visual, molecular and other screening methods); Haploids (anther, ovule culture and bulbosum technique, detection of haploids, applications); Endosperm culture, triploid production and its application; Protoplast culture, somatic hybrids and cybrids, selection strategies and applications; Secondary metabolites, hairy root culture, molecular farming, scale up studies using bioreactors; Ex situ conservation, short and long term storage of germplasm; Applications of tissue culture in commercialization; In vitro methods of crop improvement using transgenic technology and their Implications

BIO-IHBT-2021

Molecular Breeding of Plants Introduction to molecular breeding; Techniques in molecular breeding; Morphological and Molecular markers, QTL analysis; Application of molecular breeding in plants, Mapping populations (F2, Back crosses, Recombinant Inbred Lines , Near Isogenic Lines and Doubled Haploid lines). Molecular mapping and gene tagging of important traits, Marker-assisted selection, Gene pyramiding, Association mapping, Genomic selections.

BIO-IHBT-2023

Natural Resource Management Sustainable agriculture, Soil fertility and productivity, SOM, Nutrients function, Dynamics of major plant nutrients, nutrient use efficiency, IPNMS system, Precision agriculture, Growth Analysis, Crop response function, Economics of Agroforestry systems

BIO-IHBT-2024

Final Draft

Bioresources and Bioprospection

Phyto-taxonomy principles and fundamentals, Hotspots, Mega-diversity, Threat categorization, Conservation initiatives, Principles and Practices of Ecology, habitats, Biomes, Community and continuum, Community organization, Diversity, Succession, Productivity, Trophic organization and Plant invasion, Principles of remote sensing, Sensors, Platforms, Digital image processing, Introduction and component of GIS, GIS data types, GIS analysis. BIO-IHBT-2027

BIO-IHBT-2311

Bioresource Production Systems Advances in Soil-plant-water Relationship: Energy concepts, Physiomorphological behaviour of plants, Soil physico-chemical properties, isotopes and radiation techniques, Metabolic and hormonal responses, Water use efficiency, Crop growth and yield, adaptation of plants to water variation Nutrigenomics Nutrition and its importance in human health, nutrition and human genetic diversity, epigenomicc and nutrition, ethical issue and social implication, nutritional enrichment and quality improvement of food products, nutrient toxicity and safety assessment, national and International standards, regulations and recommendation for human nutrition

BIO-IHBT-2312

Advances in protected cultivation of flower crops Crop introduction, structures, external factors influencing plant growth and flowering, propagation, growing media and bed preparation, plantation, varieties, deficiency and toxicity symptoms of major and micro-nutrients, fertigation, method of crop development, crop protection, yield, grading, and post-harvest handling.

BIO-IHBT-2313

Biofertiliser Technology Plant Growth Promoting Bacteria, Mycorrhizae, Actinorhiza, Current Advances in Microbial Bio-Inoculants, Latest Concepts in Taxonomy of Nitrogen Fixing Microorganisms, Plant Growth Promoting Rhizobacteria, Mechanism of Nitrogen Fixation, Molecular Basis for Legume Rhizobia Interaction, Nitrogen Fixation in Free Living and Associative Bacteria, Actinorhizal Symbiosis, Role of Biotechnology in Agriculture.

Final Draft

300 level courses Course number

Course Content

BIO-IHBT-3001

Seminar Course (compulsory) Two parts- theory and practice Theory (1 class and one invited speaker): Understanding listeners ; organizing content; creating presentation; using visual aids; vocal impact; presentation skill; maintaining confidence and building positive image; and managing interactive session. Practice:

BIO-IHBT-3002

Delivering seminar on a specific topic.

Cancer Biology Introduction to cancer, cancer types and their prevalence, diseased and cancerous cell: morphological and microscopic features, important tumor markers, molecular basis of Key Players like carcinogens, tumor virology, oncogenes, tumor suppressor genes, cell cycle regulation in cancer development, role of genomic instability in cancer pathogenesis, Histone acetylases/deacetylases in cancer progression, Understanding of posttranscriptional and posttranslational modifications in cancer cell, angiogenesis and malignancy, stem cell biology & cancer stem cells, Hypoxia/ tumor cell microenvironment and important signaling pathways involved in cancer progression, Systems Biology in cancer, epigenetics in cancer, MicroRNAs and cancer, cell death: nacrosis and apoptosis. Discovery and clinical validation of a targets in cancer, Pharmacokinetic and Pharmacodynamic parameters of important anticancer drugs, tools, techniques & important parameters involved in screening new bioactive(s) as possible anticancer agent(s), Cell cycle regulators: Role as therapeutic targets in cancer, gene silencing and RNAi technology in cancer treatment. Role of Histopathological & Immunocytochemical techniques in cancer diagnostics and research, initiation and propagation of cancer cells in cell culture systems: Evaluation of important properties and their relevance with human biology, Pathways involved in cell differentiation/ immortalization in cancer. Aggressive tumors: Gleason score in pathology, Orthotropic and xenografted models: Importance and their limitations in understanding cancer

BIO-IHBT-3003

Cell and Tissue Engineering Molecular mechanisms regulating metabolic pathways and cellular processes, Recombinant technology, optimization and upscaling of engineered cells /tissue for higher metabolite production

BIO-IHBT-3004

Frontiers of Biology: Synthetic Biology Molecular biology of metabolic processes in plants and microbes. Molecular regulators of metabolic pathways. Approaches of engineering metabolic pathways in plants and microbes

BIO-IHBT-3-

Final Draft

Advanced Bioinformatics

005 Databases and resources in Bioinformatics, Gene expression analysis, Sequence analysis and algorithms, Next generation sequencing, Non-coding elements, Structural Bioinformatics, Programming and Scripting, Statistics

BIO-IHBT-3007

Nanobiology Nanobiotechnology and nanomaterials, Nanomaterials synthesis, Characterizations of nanoparticles, Biomolecules- nanoparticle interaction, Applications in nanomedicines and nanodiagnostics.

BIO-IHBT-3009

Gene Environment Interaction Recent advances in plant responses to biotic and abiotic stresses. Impact of environmental changes at molecular and cellular levels in plants.

BIO-IHBT-3011

Microbial Diversity and Habitat Ecology Current developments in microbial taxonomy, phenotypic microarrays, chemotaxonomy, nucleic acid and protein based methods, explorations for yet to be cultured microorganisms, metagenomics approach and recent topics on various groups of microorganisms, basis of adaptation to extreme environments, biotechnological applications of extremophilic microorganisms, industrially important extremophilic enzymes, assignments and discussions

BIO-IHBT-3013

Advances in Crop Disease Management Genetic improvement of microbial biocontrol agents-metabolites, rhizosphere colonization, disease control; Mass multiplication of biocontrol agents, delivery systems, monitoring, commercial biopesticides, quality control of biocontrol agents; Enzyme based formulations-status and problems Molecular diagnostic methods, pathogen-derived resistance, genetic engineering approaches to develop disease resistance plants, biosafety issues related to GM crops Integrated Disease Management and Integrated Pest Management strategies for control of viruses and their vectors RNAi silencing in plant disease management

BIO-IHBT-3311

Plant Viruses as Expression Vectors for Vaccines, Gene Silencing, Drug Delivery Vehicle Protein expression/vaccine production; drug delivery; functional characterization of plant genes (VIGS vectors)

BIO-IHBT-3312

Dietary Supplements Dietary supplements and their relation to nourishment, Nutraceutical and Functional food, bioactive molecules as dietary supplements, interaction between bioactive dietary supplement in specific diseases, in vitro cellular and molecular mechanism of bioactive molecules and safety assessment.

BIO-IHBT-3313

Advances in Phytogenetic Remodeling Genetic basis of generation advancement, mating systems, apomixes and its applications, Inheritance of qualitative and quantitative characters, Response and aids to selection, Gene pool concept, plant introduction and role of plant

Final Draft

genetic resources in plant improvement, domestication, Hybridization and selection methods for self and cross-pollinated plants, combining ability, genetic basis of heterosis and inbreeding, development of inbreds, Development of hybrids, self incompatibility and male sterility in crop plants and their commercial exploitation, development of synthetics and composites; improvement of asexually/clonally propagated plants, quality seed production, concept of plant ideotype, Plant breeders rights.

BIO-IHBT-3314

Special Tech for Phytogenetic Remodeling Nature and classification of mutations; mutagens; factors affecting mutagenesis, Induction of polyploidy, role of mutation and polyploidy in plants; wide hybridization, barriers to crossability and methods to overcome, cell and tissue culture, micropropagation, in vitro screening for resistance to biotic and abiotic stresses, haploids and doubled haploids (DH) production, embryo culture and its applications, somaclonal variation; protoplast culture and protoplast fusion

BIO-IHBT-3315

Biometrical Appro to Phytogenetic Remodeling Foundations of biometrical concepts; continuous variation - its nature and origin; polygene concept; scales and transformation; components of means and variance; heritability; prediction of response; mating designs; combining ability analysis using line x tester and diallel approach; genotype x environment interaction and stability analysis; genetic divergence; genotypic and phenotypic correlations; path-coefficients and discriminant function in plant selection

BIO-IHBT-3316

Fungal Pathogenesis in Plants principles and concepts in host-pathogen relationship, recognition concept and infection for pathogens and non-pathogens; role of enzymes, toxins, growth regulators in disease development; oxidative burst; phenolics, phytoalexins, PR proteins, elicitors-defense strategies, signal transduction, systemic acquired resistance and induced systemic resistance structural genes, defense genes, hypersensitive reaction, reactive oxygen species, phytoalexins, programmed cell death, viral induced gene silencing, R-gene expression and transcription profiling, mapping and cloning of resistance genes and marker-aided selection, gene pyramiding

BIO-IHBT-3317

Viral Pathogenesis in Plants Manipulation of host and insect vectors by viruses for their transmission; Replication, plant virus interactions and plant responses to biotic stress ; Mechanism of action of viral suppressors of RNA silencing; endogenous suppressors employed by plant viruses to overcome silencing; viral sRNAmediated regulation of gene expression in compatible interactions, transcriptome and proteome dynamics in response to infection

BIO-IHBT-3318

Advances in protected cultivation of flower crops Crop introduction, structures, external factors influencing plant growth and flowering, propagation, growing media and bed preparation, plantation, varieties, deficiency and toxicity symptoms of major and micro-nutrients, fertigation, method of crop development, crop protection, yield, grading, and post-harvest handling.

BIO-IHBT-3-

Final Draft

Crop Protection

319

Advanced Insect Toxicology Principals of insecticide toxicology; classification of pesticides, structure and mode of action of pesticides, degradation of pesticides by various agents, evaluation of insecticide toxicity, hazards of pesticides to human, joint action of insecticides, factors affecting toxicity of insecticides, insecticide compatibility, phytotoxicity, metabolism; pest resistance to insecticides, resistance management, pest resurgence. Safe handling of insecticides, diagnosis, and insecticide-poisoning treatment. Integrated Pest Management Trends in the development of Integrated Pest Management in national and international level, IPM Theory and Practice, economic threshold concept and economic consideration, Biological control agents, Integration of different methods of pest management. Cost-benefit ratios, case studies of successful IPM programmes.

BIO-IHBT-3320

Epigenetics and Chromatin Organization Introduction to epigenetics; Techniques in epigenetics; Epigenetics in plants evolution, adaptation and environmental stress, Chromatin structure; Organization of nucleosome and chromosomes; Molecular aspects of cell division and cell cycle. DNA replication in Prokaryotes and Eukaryotes. Transcriptional Gene Regulation: Operon Concept, Transcription Factors, Promoters, cis-regulatory elements and enhancers; Gene Silencing: Transcriptional gene silencing, Post transcriptional gene silencing; Small RNAs and their mechanism of regulation;RNA processing and Inron splicing

BIO-IHBT-3321

Final Draft

Crop Modelling and System Research Systems-definition, input-output relationships, crop modeling-static descriptive and explanatory models, modeling techniques, Crop modeling- methods for water and nitrogen stress effects, data requirement and limitations, Modeling crop-environment interaction, applications of simulation modeling in environmental impact assessment

IICB 100 level courses Course number

Course Content

BIO-IICB-1001

Biostatistics Summarization of Data: measures of center, dispersion, skewness Dependence of variables: Correlation, linear regression, logistic regression Basic probability distributions: Binomial, Normal, Chi-squares. Estimation of parameters: method of moments, maximum likelihood Testing of hypotheses: (a) parametric tests: t-test, z-test, chi-squares test, ANOVA (b) non-parametric tests: Mann-Whitney, Kruskal Wallis, Kolmogorov-Smirnov

BIO-IICB-1002

Computation/bioinformatics Computers: Introduction, Evolution and Classification of computers. Fundamentals of computing. Bit and Byte, Introduction to types of Hardware and Software. Components of Computer. Introduction to operating systems. Introduction to Computer Viruses. Network: Introduction. Network structure and architecture, Hierarchical networks, Ethernet and TCP/IP family of protocols, transport protocol design. Types of network, Topologies of network, Router, Switch, Data Communication, Concept of Wireless networking, LAN, WAN, MAN, Security of the network, Fire-walls, Network Applications Information Technology: Concepts of client Server Architecture, Concept of search Engine, Database search engines. Introduction to Internet Introduction to Word, Powerpoint and Excel Introduction to Bioinformatics: History of Bioinformatics, Genome sequencing projects, Human Genome Project, Applications of Bioinformatics. Introduction to databases, Type and kind of databases, Applications and limitations. Literature Search Databases, Nucleic acid and protein databases, Animal and plant databases, Ensembl Genome project TIGR database, Biotechnological databases, Motifs and Pattern Databases, Databases for species identification and classification, Structural databases. Database Retrieval and deposition systems. Web tools and resources for sequence analysis: Pairwise and multiple sequence Alignment, Sequence similarity search: BLAST, Pattern recognition, motif and family prediction, Restriction map analysis, primer design, Gene prediction, Phylogenetic Tree, Protein structure prediction and visualization.

BIO-IICB-1003

Basic Chemistry Thermodynamics Solutions and Ions Chemical bonding and molecular structure Chemical Kinetics Stereochemistry Introduction to drug discovery (Medicinal chemistry approach) Drug target, discovery and development (forward and reverse approach

BIO-IICB-1004

Research Methodology, Communication/ethics/safety Philosophy and structure of scientific thoughts, Objective and Motivation of Research,

Final Draft

Meaning of the Research, What constitutes a research topic? How to select a research topic?, Importance of literature review, Selection of appropriate methodology, Collection of data, Interpretation of data, Writing research paper, Paper presentation in scientific conference, Statistical methods, Importance of documentation, Procedure for Hypothesis Testing, Values and Ethical Problems, Criteria of Good Research, Good laboratory practice, Chemical, Radioactive and Biological safety: Possible hazards and precautionary measures; do and don’ts upon exposure Research methodology, communication, ethics, safety Asking the right questions: Originality, Depth, Precision can co-exist Formulating and refining the hypothesis: Those who do not learn from the past are condemned to repeat it Study design: Recognizing and minimizing bias Experiment design: Sometimes less is more and the importance of controls Good lab practices: Record keeping, organizing data, organizing the lab space Data interpretation; objectivity, quantification, double blind studies and necessity of statistics Comunicating your data:writing up your research Comunicating your data: presenting your findings Radiation safety Chemical and Biosafety Intellectual property rights What is ethics, the different interpretations & historical instances of unethical science Case studies: Data fraud/ plagiarism and Human Ethics violation

Final Draft

200 level courses Course number

Course Content

BIO-IICB-2001

Biotechniques

1.Chromatography : Different chromatographic techniques, HPLC 2.Centrifugation: Principles and uses, application in modern biology 3.Electrophoresis: Theory and hypothesis, SDS-PAGE, Western Blot, 2D gel electrophoresis 4.Mass spectrometry and Protein identification: Principles and theory, application in proteomics 5.Colorimetry : ITC, DSC, Determination of protein stability, analysis of binding properties 6.Surface Plasmon resonance: Techniques and its use in biology 7.Optical spectroscopy: Absorption, fluorescence, FT-IR, Raman and other techniques 8.FACS: Principles and application 9. Imaging: Electron microscopy, Confocal microscopy, Atomic force microscopy, In vivo imaging 10. NMR: 1D NMR, 2D NMR and application in structural biology 11. X-Ray crystallography: Basic theory and its application in structural biology

BIO-IICB-2002

Biology of Macromolecules 1. 2. 3. 4. 5. 6. 7. 8.

9. 10. 11. 12. 13. 14. BIO-IICB-2004

Protein – Nucleic acid interactions Synthesis and degradation of macromolecules The folding process and structural background Modular structures, Protein flexibility, Domain motions, Domain-swapping; and Large macromolecular complexes Enzyme activity, receptor binding and regulation, binding specificity, catalysis and cooperativity in enzymes and receptors Methods for the determination of macromolecules structure and interaction Macromolecular function in transcription, translation, signaling and other fields of cell biology, integration and control mechanisms Structure and evolution of important protein motifs and folds. [e.g. Coiled-coil proteins, helical bundles, signaling domains (sh2, sh2, pdz etc), Immunoglobulin-like proteins, kinases, TIM barrels, DNA/RNA binding motifs Principles of macromolecular engineering The most important metabolic pathways and regulation Relation between sequence, structure and function Biological structure databases Computer modeling of secondary- and tertiary structure of proteins and nucleic acid based on sequence data Enzyme/receptor-based drugs-rational drug design

Biology of Infection Parasitology 1. Malaria Parasite General nature of Apicomplexan parasite; Biology of malaria parasite; Antimalarial drugs; Mechanism of drug resistance; Drug target and new antimalarial development; Host –parasite interaction, mechanism of multi-organ failure 2. Leishmania Parasite Biology of Leishmania parasite;Anti-Leishmanial drug; Host-parasite interaction 3. Entamoeba Protozoa Life pattern and pathogenecity 4. Nemathelminths

Final Draft

Ascaris Sp.; Biology and mechanism of pathogenesis Filaria Sp;Biology and mechanism of pathogenesis 5. Medical Parasitology Sanitation and parasite infection;Detection of parasite infection; Precautionary measure to prevent parasite infection; Origin of new strain; Parasite and malnutrition; Ecology of parasite and vectors

Bacteriology 1. General basic characteristics and fundamental structure of bacteria, particularly structures important for pathogenicity and virulence in microbial infections, brief description of some major medically important bacterial pathogens involved in organ and system infections in humans, biological safety in handling pathogenic bacteria 2. Molecular laboratory diagnosis of infection, definition of bacteriostatic and bacteriocidal agents, principles of antibiotic action mechanisms and molecular basis of antibiotic resistance and its importance in healthcare 3. Bacterial growth and metabolism, molecular basis of survival mechanisms under various in vivo and in vitro stressful environments 4. Importance of different virulence factors, namely, exotoxins, endotoxin, secretion systems, invasive properties, antigenic variation and other mechanisms to avoid the immune system 5. Regulation of virulence gene expression, motility, chemotaxis etc., importance of bacterial two-component signaling systems; Role of different mobile genetic elements in evolution of pathogens

BIO-IICB-2006

Protein Science and Proteomics: Protein Science: 1. Basic building blocks of protein and their composition, chemical behavior, properties. 2. Peptide bond, geometry and parameters; Backbone geometry and parameters, side chain geometry and parameters, Ramachandran plot. 3. Primary, secondary, tertiary and quaternary structures. 4. Protein structure stabilizing forces – hydrogen bond, electrostatic bond or salt bridges; hydrophobic forces 5. Protein folding, dynamics and thermodynamics. 6. Protein: from gene to function. 7. Protein and diseases. 8. Some important proteins in cellular functions. Proteomics:

1. Protein cloning, expression and purification. 2. Protein chromatography systems and purification procedures – HPLC, FPLC etc. 3. Bioinformatics of protein sequences – sequence analysis, comparison, alignment etc. 4. Mass spectrometry – introduction to mass spectroscopy, gel mass spectroscopy, LC-MS, LC-MS-MS, MALDI-TOF 5. Protein NMR, FTIR Raman, CD 6. Protein Crystallography.

Final Draft

BIO-IICB-2012

Cell Biology and Cell signaling 1. Cell growth and division, including cell cycle: Phases of cell cycle, Regulation of cell cycle, Cell cycle check point, Cell growth 2. Intracellular sorting of proteins: Nuclear import and export mechanism; Organelle targeting; Transport of protein to cell surface; Soluble protein sorting 3. Cell adhesion, cell junction and Extra Cellular Matrix: Cell adhesion molecules; Cell Junction; Extracellular matrix; Cell-cell recognition 4. Cytoskeletal structure-function and related macromolecules: Cytoskeletal proteins; Role in vesicular movement; Cellular morphology and cytoskeletal protein; Drug modulating cytoskeletal 5. Signal transduction pathways: Extracellular signals; Intracellular signals; 2nd Messengers; Signal transduction pathways 5. Cell death and proliferation: Programmed cell death; Cell renewal system; Mitochondria and apoptosis; ER-stress 6. Cellular starvation, stress and Autophagy: Oxidative and nitrosative stress; Stress response; Autophagic vacuole turnover; Cellular homeostasis 7. Metabolic disorder and signaling aberrations: Abnormal Signaling in Cancer; Signaling for diabetic complication Angiogensis; Signaling for failure in diabetes

BIO-IICB-2026

Bioinformatics 1. Specialized and derived databases for bio-molecular sequences and structure: Genome Databases of model organisms, human, pathogenic microbes & human micro biome; RNA Fold database, Small molecule databases; Structural databases and Structural comparison databases like CDD, FSSP, DALI etc. 2. Functional genomics and whole genome data-mining techniques: Application of sequence-based/structure-based approaches to assignment of gene functions; Identification of Virulence Cassettes & other genome islands; Analysis of gene repertoire, repeat sequences, CpG islands etc.; Prediction of miRNA/siRNA sequences & their putative targets; Use of SNPs for identification of genetic traits 3. Gene expression and Mass spectroscopy data analysis: Analysis of DNA microarray data (especially clustering approaches) and correlation of gene expression data to biological processes. In silico tools for analysis of proteomics data (Tools available at ExPASy Proteomics server); Computational methods for identification of polypeptides from mass spectrometry data. 4. Biological Pathway and interaction network analysis: Databases on metabolic pathways such as KEGG, EMP; Databases and tools for analysis of protein-protein interactions

5. Molecular modeling and simulation: Basic concepts in molecular modeling; Computer representations of molecules with different surface rendering; Principles for fold recognition, 1D profiles and threading approaches; Principles of molecular dynamic simulation; Concepts of force fields: representations of atoms and atomic interactions, potential energy; Purpose & concepts in 3D structure comparison, algorithms such as FSSP, VAST and DALI

Final Draft

6. Drug discovery and design: Drug discovery cycle; Drug discovery Vs design; Role of Bioinformatics in drug design;Target identification; Structure-based drug design; Modeling of target-small molecule interactions 7. Genome assembly & annotation: Contig Assembly, Prediction of Genes, Promoters & Splice sites 8. Taxonomy and Phylogenetic analysis: Basic concepts in systematic; Phylogenetic analysis algorithms such as Maximum Parsimony, UPGMA, Neighbor-Joining; Probabilistic models like Maximum likelihood algorithm. 9. Concept of important algorithms applied in bioinformatics: PSSM, HMM, NN, SVM, DP: 10. Concepts and application of advance statistical analysis in bioinformatics.

BIO-IICB-2346

Molecular and Cellular Immunology 1. History of immunological ideas and cellular components of immune system Transplantation antigens: structure, function, genetics, transplantation 2. Phagocytosis and antigen presentation Fc receptor and scavenger receptor mediated phagocytosis, markers to follow phagocytosis, presentation of endogenous and exogenous antigens, cross-presentation 3. Antibody structure, antigen-antibody interactions, binding site, affinity, avidity, Fc functions, molecular biology of immunoglobulins; B cell triggering: Tcell-B cell Interactions 4. Humoral immune response and cytokines: Signaling through B cell receptors, plasma cell differentiation, proinflammatory / anti-inflammatory effects of cytokines, transcriptional control of cytokine synthesis 5. Structure of lymphoid organs, ontogeny of lymphoid cells; Complement system and disease : Classical and alternative pathways of complement activation, complement regulation and deficiencies 6. Immune response to parasitic infections : Cell mediated immunity: delayed reactions, immunodeficiency; Allergy, Arthus reaction, serum sickness, inflammation; Autoimmunity: regulation of immune response and autoimmune diseases; Tutorial

Final Draft

300 level courses Course number

Course Content

BIO-IICB-3001

Seminar & Critical Appraisal

BIO-IICB-3002

Cancer Biology : 1. Cancer Immunology: The immunological status of adaptive and innate immune cells in cancer, cellular interactions between immune and cancer cells in tumor progression or rejection, immunological mechanisms, regulation and function involved in host responses to tumors, anti-tumor immunity, cancer-induced immune tolerance, immunosuppression, dysregulation of the immune system and poorer outcome in the disease 2. Cancer stem cells : Origin/Hypothesis/Concept ; Signaling pathways in cancer stem cells 3. Cell signaling in cancer : Description of major classes of cell signalling: cell death signalling, cell survival signalling and developmental/stem cell signalling; signal networking and chemotharapy 4. Oncogenesis and epigenetics in cancer :Oncogenes and their regulation in signaling aberration; Acetylation/methylation in DNA and histones; Silencing/De-silencing of gene expression 5. Metabolic Engineering in cancer; Metagenomics and cancer 6. Cancer biomarkers and diagnosis : Selection of clinical specimens, recent advancement for identification of biomarkers through different approaches like genomics, proteomics and glycomics in combination with molecular pathology with potential clinical value; Application of biomarkers for cancer staging and personalization of therapy at the time of diagnosis to improve patient care. 7. Cancer drug discovery : Identification of lead molecules, target identification in cancer cells; combined approaches (in vitro, in vivo and in silico) for validation, various steps involved towards successful drug discovery; immunotherapeutic approaches e.g. cancer vaccines, monoclonal antibodies, adoptive immune cell transfer etc. and combination strategies to treat malignancies 8. Angiogenesis and metastasis 9. Project writing

BIO-IICB-3003

Cell and Tissue Engineering 1. Introduction 2. Cell & Tissues : Definition of cells, tissues and organs 3. Tissue culture: Propagation of somatic cells 4. Stem cells : Source, biology and therapeutics 5. Biology of blood and artificial blood 6. Biology of skin and artificial skin 9. Biomaterials: source and usage 10. Hybrid cells: theory and instrumentation 11. Tissue transplantation 12. Biomolecules: angiogenic factors, growth factors 13. Mouse genetics 14. Transgenics, Knock-out

Final Draft

BIO-IICB-3006

Microbial pathogenesis 1. Parasitic pathogenesis : An introduction to protozoan parasites: Entaemoeba histolytica: Life cycle, morphology and pathogenesis. Kinetoplastidae: Leishmania and Trypanosome : morphology, life cycle, mode of infection and molecular biology (replication of KDNA and RNA editing). Plasmodium : morphology, life cycle and mode of infection. 2. Major malaria vectors of India: distribution, Bio-ecology, potentiality, present sustainability status, form and function. 3. Helminthes and Nematodes: General introduction. 4. Host parasite interactions: Vector biology and its importance in parasite transmission, antigenic variation, potential drug targets, virulence factors, mechanism of drug resistance, vaccine strategies and proteomic approaches. 5. Organelle variations in protozoa: glycosomes.

Cytoskeleton, mitotic spindle, hydrogenosomes,

6. Bacterial pathogenesis: Modulation of host signaling pathways during bacterial infection ; Bacterial strategies to overcome host defense; Cell-cell communication in bacteria; Role of the microbiome in health and disease; In silico data mining tools for bacterial genomics BIO-IICB-3008

Neurobiology: 1. Introduction: Introduction to central and peripheral nervous system; Basic elements of nervous system (neuron, glia and fibers). 2. Developmental Neurobiology : Neural tube formation, migration, differentiation, axonal guidance, myelination, synaptic re-arrangement and pruning; factors like growth factors, interleukins, steroid super-family, etc. on brain morphogenesis 3. Developmental neurological diseases: Neural tube defect, Autism, Dyslexia, Schizophrenia etc. 4. Functional & Chemical Neuroanatomy: Anatomical organization of central nervous system in relation to regulation of functions - brain stem autonomic regulatory nuclei, cardiovascular & respiratory functions of medulla & pons; chemical organization of the central nervous system in relation to anatomy - basal ganglia, anatomy, chemistry and functions; forebrain limbic system – arousal, fear, stress and feeding; integration of sensory and motor systems – peripheral sensory pathways and receptors, pain, auditory & visual systems, motor cortex output & pathways; neurotransmitters, neuromodulators and synaptic transmission. 5. Neuronal Physiology: Electrical signaling; action potential; voltage gated and receptor gated ion channels 6. Neural signaling: Receptors, second messengers and signaling 7. Epigenetics in brain development and behaviors: Epigenetic inheritance, chromatin regulation and histone modifications, Specificity of DNA methylation response 8. Neural stem cells and differentiation: Neural stem cells characteristics; differentiation into specific neural cells; stem cells in the adult brain; migration of stem cells in response to injury.

Final Draft

9. Research tools in neuroscience : Brain stereotaxy; patch clamp; LCDM: MRI; CT; PET; NMR-S, etc. 10. Overview of neurodegeneration : Basic mechanism of neuronal apoptosis such as extrinsic and intrinsic apoptotic pathways; protein aggregation, proteosomal dysfunction, aberrant cell cycle activation 11. Neurodegenerative diseases: Use of animal models of human dysfunctions; pathophysiology of dementia and movement disorders; causes and corrections; regenerative therapy; deep brain stimulation 12. Neurogenomics in development and diseases: Detection of genes for neurological disorders; the study of gene expression in the CNS; creation of transgenic models of neurological disorders. BIO-IICB-3346

Genomics 1. An introduction to transition from genetics to genomics Family Pedigree Karyotyping and Linkage Analysis DNA Sequence Analysis The Need for an Animal Model System Phenotypic heterogeneity in monogenic disorders The need for genomic information 2. Genome Sequence Acquisition How Are Genomes Sequenced? The lesson from Unicellular Genomes The lesson from Metazoan Genomes 3. Comparative Genomics in Evolution and Medicine Comparative Genomics Evolution of Genomes Genomic Identifications Biomedical Genome Research 4. Genomic Variation Human Genomic Variation Ethical Consequences of Genomic Variations 5. Genomic Expression Basic Research with DNA Microarrays Alternative Uses of DNA Microarrays Applied Research with DNA Microarrays Improving Health Care with DNA Microarrays 6. Whole Genome Perspective Why Can’t We Cure More Diseases? Genomic Circuits in Single Genes Integrated Genomic Circuits 7. Genomics of Microbes and Microbiomes Genome architecture of microbes Dynamics of Microbial Diversity Metagenomics- DNA sequence from multiple organisms The Human microbiome

BIO-IICB-3347

Eukaryotic Gene Regulatory Mechanisms In each module the study material will consist of a few original research articles covering some of the latest developments in the field, to be chosen by the instructors for open discussion in the class. Discussion may include one or more of the following topics. Students are expected to brush up their post graduate knowledge of these topics before attending the lectures.

Final Draft

1. Chromatin Structures and Epigenetics Nucleosome assembly and the modification of nucleosomes and of DNA/ The assembly of chromatin into higher order structures/ Different aspects of heritable patterning of gene expression and the biological importance of epigenomes/ Mechanisms of inheritance as well as imprinting, X inactivation and the role of RNA in establishing silent chromatin/ The impact of chromatin structure on differentiation, cell plasticity and development. 2. Transcriptional Regulation and Gene Expression Regulatory interplay between transcription factors: Regulatory DNA sequences (promoters, enhancers, locus control regions) /General transcription machinery/ Transcription factors: cell‐specific and ubiquitous regulatory factors/ Mechanistic aspects of transcription activation / Chromatin, histones, DNA methylation /Gene regulatory networks /Transcription factors in health and disease/ Transcription factors as the final integrators of signaling cascades. 3. Structure, Processing, Trafficking and Function of RNA Chemistry and structure of RNA/ major lectures of cellular RNAs (mRNAs, tRNAs, rRNAs, snRNAs, and the newly discovered small regulatory RNAs/pre‐mRNA processing with emphasis on splicing and polyadenylation/ biogenesis of tRNA and rRNA/ biochemistry and function of RNA interference (RNAi) and microRNAs/ RNA trafficking in the cell/ RNA quality control and RNA degradation/regulated mRNA translation during development/ RNA‐protein interactions and major lectures of ribonucleoprotein particles;RNA granules and bodies /evolution of RNAs: The RNA world/ 4. Translational Control and Post-translational Protein Modification The translational control: Codons and frame shifting, attenuation, phosphorylation, and transformation/the role of translational control in the regulation of cell growth and differentiation.

BIO-IICB-3348

Chemical Biology An overview of Chemical Biology Protein-protein interactions and its inhibitors Ligands for protein surfaces Ligands for Nucleic Acid surfaces Chemical Genetics Synthetic and semi synthetic proteins Applications of chemical biology, enzyme based biosensors, catalytic antibody

BIO-IICB-3349

Synthetic & Systems Biology 1. Synthetic Biology: Concepts, useful definitions, basic cellular and molecular biology, biological components and properties Enzyme kinetics, gene structure and control of gene expression Intrinsic and extrinsic noises Basic knowledge in network circuits like feedback loops, switches, oscillators, feed forward loops, pulse generators, logic and filter circuits Synthetic networks, example and applications Metabolic network structure and metabolic or pathway engineering, applications of synthetic biology in pathway engineering Whole genome synthesis and related areas 2. Systems Biology: Introduction to systems biology

Final Draft

Philosophy of systems biology Emergent properties of the system Biological robustness Experimental approaches in systems biology Global approaches to data collection Designing single cell experiments Utility of model organisms in systems biology Application of microfluidic and nanotechnology devices Integration of information derived from various data types Mathematical and statistical modeling of biological systems Graph theory Logical steady state approach Flux balance analysis Multivariate statistics Few examples of biological systems Cell signaling network Immune system network Transcriptional network Metabolic network

BIO-IICB-3350

Understanding Glycan structure & their role in Chemical Biology 1. Overview, as an introduction to the topic and to emphasize the importance of carbohydrates in food and nutrition and biology.Discussion on the structures, shapes and various sources of carbohydrates. This may complement course “MC630 Structure and Function of Biomolecules” in certain respects. 2. Reactions of carbohydrates: Discussion on the relative reactivities of the hydroxyl groups; convergent synthesis of biologically active oligosaccharides, glycolipids and glycoproteins. Discussion on the chemical and enzymatic methods after highlighting the need for synthesis. 3. Carbohydrate Therapeutics: Discussion on various drugs (aminoglycoside antibiotics including glycopeptides, enediynes, macrolides, anthracyclines, etc., alkaloid, steroid and terpenoid. Glycosides: polyphenol glycosides etc.) that contains carbohydrate moiety (moieties) including polysaccharide therapeutics. 4. Polysaccharide vaccines: Carbohydrate microarray. Understanding glycan structures and their analogues. Carbohydrate dynamics. The role carbohydrate structures in normal and diseased states.

BIO-IICB-3351

Modern Drug Discovery & Design 1. In-silico drug design, and docking studies. Fragment based drug design; Structure-activity relationship (SAR), Quantitative structure-activity relationship (QSAR); Concept of drug, classification of drugs, Molecular basis of drug action: basic ligand concept, agonist, antagonist, partial agonist. Chemistry & therapeutic uses of bio-active molecules . 2. Physicochemical properties Hydrophobicity, electronic effects, area; Stability

Final Draft

Steric factors,

solvent accessible surface

3. Lead generation Diversity oriented synthesis, Combinatorial chemistry; Sources of drugs, lead modification, prodrugs and soft drugs. Peptidomimetics, anti-sense RNA, DNA, PNA, LNA. 4. Pharmacokinetics, Pharmacokinetics, Bioavailability, Pharmacodynamics, drug metabolizing enzymes, route of administration, route of excretion, halflife, analysis, bioanalytical methods in mass spectrometry, therapeutic window

5. Drug delivery systems. Nano-particle drug carrier, liposomes etc.; Recombinant DNA products (vaccine), peptide drugs etc.; MAb :anti-idiotype vaccines, therapeutic drug targeting, diseasespecific antigens

6. Drug target identification: Qualification a drug target, Rationale and Approaches: (a) Forward Genetics and Reverse Genetic/Chemical Genetics; (b) Gene-network; (c) Trancriptomics; (d) Interactome 7. Drug target validation: In vitro/in vivo models; High Throughput Screening (HTS) Assay designing Chemical and genetic knock down studies 8. Lead optimization and targeting and clinical trial Qualification for clinical trial Preclinical studies for toxicity, Efficacy Human clinical trials for safety.

Final Draft

IICT 100 level courses Course number

Course Content

BIO-IICT-1001

Biostatistics Summarization of Data: measures of center, dispersion, skewness Dependence of variables: Correlation, linear regression, logistic regression Basic probability distributions: Binomial, Normal, Chi-squares. Estimation of parameters: method of moments, maximum likelihood Testing of hypotheses: (a) parametric tests: t-test, z-test, chi-squares test, ANOVA (b) non-parametric tests: Mann-Whitney, Kruskal Wallis, Kolmogorov-Smirnov

BIO-IICT-1002

Computation/bioinformatics Computers: Introduction, Evolution and Classification of computers. Fundamentals of computing. Bit and Byte, Introduction to types of Hardware and Software. Components of Computer. Introduction to operating systems. Introduction to Computer Viruses. Network: Introduction. Network structure and architecture, Hierarchical networks, Ethernet and TCP/IP family of protocols, transport protocol design. Types of network, Topologies of network, Router, Switch, Data Communication, Concept of Wireless networking, LAN, WAN, MAN, Security of the network, Fire-walls, Network Applications Information Technology: Concepts of client Server Architecture, Concept of search Engine, Database search engines. Introduction to Internet Introduction to Word, Powerpoint and Excel Introduction to Bioinformatics: History of Bioinformatics, Genome sequencing projects, Human Genome Project, Applications of Bioinformatics. Introduction to databases, Type and kind of databases, Applications and limitations. Literature Search Databases, Nucleic acid and protein databases, Animal and plant databases, Ensembl Genome project TIGR database, Biotechnological databases, Motifs and Pattern Databases, Databases for species identification and classification, Structural databases. Database Retrieval and deposition systems. Web tools and resources for sequence analysis: Pairwise and multiple sequence Alignment, Sequence similarity search: BLAST, Pattern recognition, motif and family prediction, Restriction map analysis, primer design, Gene prediction, Phylogenetic Tree, Protein structure prediction and visualization.

BIO-IICT-1003

Basic Chemistry Thermodynamics Solutions and Ions Chemical bonding and molecular structure Chemical Kinetics Stereochemistry Introduction to drug discovery (Medicinal chemistry approach) Drug target, discovery and development (forward and reverse approach

BIO-IICT-1004

Research Methodology, Communication/ethics/safety Philosophy and structure of scientific thoughts, Objective and Motivation of Research,

Final Draft

Meaning of the Research, What constitutes a research topic? How to select a research topic?, Importance of literature review, Selection of appropriate methodology, Collection of data, Interpretation of data, Writing research paper, Paper presentation in scientific conference, Statistical methods, Importance of documentation, Procedure for Hypothesis Testing, Values and Ethical Problems, Criteria of Good Research, Good laboratory practice, Chemical, Radioactive and Biological safety: Possible hazards and precautionary measures; do and don’ts upon exposure Research methodology, communication, ethics, safety Asking the right questions: Originality, Depth, Precision can co-exist Formulating and refining the hypothesis: Those who do not learn from the past are condemned to repeat it Study design: Recognizing and minimizing bias Experiment design: Sometimes less is more and the importance of controls Good lab practices: Record keeping, organizing data, organizing the lab space Data interpretation; objectivity, quantification, double blind studies and necessity of statistics Comunicating your data:writing up your research Comunicating your data: presenting your findings Radiation safety Chemical and Biosafety Intellectual property rights What is ethics, the different interpretations & historical instances of unethical science Case studies: Data fraud/ plagiarism and Human Ethics violation

BIO-IICT-105

COMMUNICATION AND WRITING SKILLS English proficiency course syllabus will be decided by the collaborative university: English and Foreign Languages University (EFLU), formerly the Central Institute of English and Foreign Languages (CIEFL)

BIO-IICT-106

LABORATORY SAFETY Lab rules and safety, Pre and post lab responsibilities, chemical hazards, reading and understanding Material Safety Data Sheets (MSDS), Hazard Assessment, Non-chemical hazards, Chemical hazards, Safe laboratory practices, Safe chemical practices, Biosafety, disposal of chemical, biological and radioactive waste. Fire extinguisher types and uses, Information on First Aid procedures, emergency eyewash, safety shower, storage cabinets, fire safety, Accident and Emergency handling, etc.

Final Draft

200 level courses Course number BIO-IICT-2001

Course Content

BIOTECHNIQUES & INSTRUMENTATION (compulsory) Principles and applications of Centrifugation, Chromatography, Electrophoresis and spectroscopy. Immuno-techniques: ELISA, Immuno-fluorescence, Immuno-histochemistry, immunoprecipitation, ChIP, etc. Automation in Drug Discovery: High-Content and HighThroughput Screening procedures.

BIO- IICT-2013

CHEMICAL BIOLOGY Science at the Interface of Chemistry and Biology; Introduction to Chemical Biology to encompass a survey of major topics, technologies, and themes in drug discovery. Screening methods for the identification of lead molecules . Current screening methods in chemical biology including cell based and target based automated assays; Overview of drug delivery systems with special emphasis on lipid mediated targeted gene delivery systems; siRNA as a tool in chemical biology; Biological applications of RNAi. Small molecule mediators of cell signaling pathways.

BIO-IICT-2015

BIO- IICT-2251

CROP PROTECTION Major pests of crops; Insect - plant relationship; Principles of insect physiology; Toxicology and pathology; Insecticide resistance and residue monitoring; Biopesticides and integrated pest management. TECHNIQUES FOR IDENTIFYING NEWER PESTICIDE MOLECULES Classification of evaluation (Agricultural pest and Public health important vectors), Larvicidal, Pupicidal, Insecticidal, Anti-feedant, Insect growth regulators. Xenobiotics exposure/effect assessment using alternate animal models, How to evaluate commercial products.

BIO- IICT-2252

BIO-IICT-2253

TECHNIQUES FOR IDENTIFYING NEWER DRUG MOLECULES An overview of the various screening methodologies including in vitro and in vivo models. Correlations between in vitro and in vivo experiments. Choosing a right model and its relevance to human disease. Principles of high throughput screening (HTS). An overview of ex vivo techniques with special reference to isolated tissue experiments. An overview of methods for identifying hit molecules from NCEs. In vitro cell culture based screening techniques in the area of diabetes.

PROTEOMICS AND ITS APPLICATION Introduction to Proteomics and its advantages over genomics. 1D and 2D Gel Electrophoresis: pI, Isoelectric focussing, 2 dimensional gel Staining methods and analysis. Protein spot/Band processing for Mass spectrometric analysis. Introduction to Mass spectrometry and application of MALDI-TOF/TOF and electrospray/ liquid chromatography - mass spectrometer. Spectral Peak Annotation and Database search. Shotgun Proteomics, Protein quantification using Mass spectrometry: ITRAQ, and SILAC. Application of chemical proteomicsin drug design, Practical Training for 1D and 2 D gel

Final Draft

electrophoresis and subsequent mock practice for Mass spectrometric analysis of processed protein spot using MALDI-TOF/TOF BIO- IICT-2254

PRINCIPLES OF PHARMACOLOGY AND TOXICOLOGY A general introduction to Pharmacology and Toxicology, Topics include absorption, distribution, biotransformation, elimination and calculation of dosages, Experimental design and data analysis for Pharmacology and Toxicology, Interdisciplinary Toxicology, Routes of administration. General principles and the application of toxicological knowledge are discussed including clinical toxicology, forensic toxicology, and risk assessment, Determination of median lethal concentration (manual calculations) Anticancer drugs and environmental agents exert their cytotoxic effects through DNA damage, The biochemical principles and molecular mechanisms underlying the toxicity of drugs and foreign agents.

BIO- IICT-2255

ENVIRONMENTAL AND MICROBIAL TECHNOLOGY Concepts of environmental Microbiology, Complexity of microbial world, Environmental Ecology and Eutrophication, Fundamentals of microbial nutrition, Overview of microbial metabolism, Microbial diversity, Microbes and climate change, Water microbiology, Biodegradation and bioremediation, Microbial biogeochemistry, Microbial biofilm and corrosion, Concepts of microbial reactors, Perception of bioenergy, Hazardous waste bioremediation Biotransformation.

Final Draft

300 level courses Course number BIO-IICT-3001 BIO- IICT-3007

Course Content

Seminar course – compulsory

NANOBIOLOGY Prerequisite courses: 214 and/or 241 Introduction to nanoscience and nanotechnology. Optical and electronic properties of nanoparticles. Morphologies [nanotubes and nanowires, fullerenes (buckyballs, graphene)] of nanoparticles. Semiconductor/quantum dots nanoparticles. Historical background of nanotechnology/nanoparticle in medicine. Several synthesis routes for nanoparticles (physical, chemical and biological) Several physico-chemical techniques (XRD, TEM, SEM, AFM, TGA, DSC, FTIR, UV-visible spectra etc.) and their basic principles for the characterization of nanoparticles. Surface functionalization of nanoparticles for development of nanoconjugates. Application of nanoparticles in various fields. Why nanotechnology is important in biology and medicine? Application of nanotechnology in therapeutics, diagnostics and drug delivery system. Different interaction of nanoparticales with biological system. In vitro and in vivo toxicity study of nanoparticles.

BIO-IICT-3012

ENVIRONMENTAL TOXICOLOGY Prerequisite courses: 217 and/or 242 Environmental Toxicology in present and future perspective (01 lecture), Environmental hazards (physical, chemical and biological aspects), Origin, sources and types of toxicants/pollutants; Dispersal/movement of toxicants in environmental compartments Ecotoxicology : Conventional and alternate models in toxicity assessment; Assessment of toxicity of pollutants; Absorption, distribution and storage of toxicants; Dose response relationships; Biotransformation and elimination of toxicants; Mechanisms of action of toxicants; Gene-environment Interactions. Pollution monitoring and Risk assessment: Tools for detection; Fate and transport. Hazardous waste management: Regulation, approaches and strategies

BIO-IICT-369

ADVANCED PHARMACOLOGY Prerequisite courses: 239 and/or 241 An outline of basic ethics in animal experimentation. Common laboratory animals, handling and care, different routes of administration of drugs and euthanasia techniques. Breeding techniques, random and selective breeding. Dose calculations in animals. Animal models in pharmacology, general perspectives, selection of suitable species and strains for disease models. Detailed study of the animal models related to inflammation, arthritis and diabetes. In vitro cell culture techniques, cell counting and cell viability assays. Commonly used isolated tissue experiments, physiological salt solutions, and recording transducers. Basic principles of pharmacokinetics, Concepts related to absorption, distribution, metabolism and Elimination (ADME), Factors influencing absorption of drugs.

BIO- IICT-370

Final Draft

DISEASE MECHANISMS

Prerequisite courses: 214 and/or 240 Hall Marks of Cancer; Mechanisms of carcinogenesis (oncogenes, tumor supressors, tumor virology, chemical carcinogens) and disease progression. Mechanisms of chemoresistance and alternative strategies to overcome; Current knowledge on tumor metastasis; Emerging trends in cancer therapeutics – role of micro RNA’s and stem cells. Introduction to factors affecting cardiovascular diseases; Pathophysiology, epidemiology and current therapeutic interventions related to atherosclerosis, hypertension and diabetes. An overview of central nervous system and neurophysiology; Neurocircuitry - circuitry level approach to understand Brain and Behavior, chemosensory circuit, reward circuit, learning and memory circuit (Cognitive disorders and mental retardation). An overview of disease mechanisms with specific emphasis on target development and plausible therapeutic interventions pertaining to Parkinson’s and Alzheimers disease. Biology of neurogenesis and Repair mechanisms (Molecular Biology of Adult Neurogenesis, Neural Progenitor or stem cells). BIO- IICT-371

INDUSTRIAL/ APPLIED MICROBIOLOGY: Prerequisite courses: 242 Introduction Industrial and environmental microbiology; Intermediate microbial metabolism for exploitation of microbes; Microbial enzymology and kinetics, Intermediate microbial metabolism; Microbial transformations; Immobilization and applications; Microbial processes for waste water management; Microbial processes for Air pollution management; Anaerobic digestion of organic solids Microbial solid waste management; Microbial fermentation; Microbial Energy Engineering; Microbial energy engineering and Biorefinery.

BIO-IICT-372

PROTEIN SCIENCE AND STRUCTURAL BASED DRUG DESIGN AND DEVELOPMENT Prerequisite courses: 214 and/or 240 Biochemistry and engineering of proteins, protein structure, structural motifs in functional regulation, methods of structure determination by NMR and crystallography, enzyme inhibitor complexes, structure based inhibitor design, modeling and bioinformatics. Enzymes: Mechanism of Catalysis, Kinetics & Regulation Protein Methods: Protein separation and purification Methods Practical Training to protein separation/detection using Western blotting, Protein structure: methods of crystallization, X-ray data collection, structure determination and analysis.

Final Draft

IIIM 100 level courses Course number BIO-IIIM-1001

Course Content

Biostatistics Summarization of Data: measures of center, dispersion, skewness Dependence of variables: Correlation, linear regression, logistic regression Basic probability distributions: Binomial, Normal, Chi-squares. Estimation of parameters: method of moments, maximum likelihood Testing of hypotheses: (a) parametric tests: t-test, z-test, chi-squares test, ANOVA (b) non-parametric tests: Mann-Whitney, Kruskal Wallis, Kolmogorov-Smirnov

BIO-IIIM-1002

Computation/bioinformatics Computers: Introduction, Evolution and Classification of computers. Fundamentals of computing. Bit and Byte, Introduction to types of Hardware and Software. Components of Computer. Introduction to operating systems. Introduction to Computer Viruses. Network: Introduction. Network structure and architecture, Hierarchical networks, Ethernet and TCP/IP family of protocols, transport protocol design. Types of network, Topologies of network, Router, Switch, Data Communication, Concept of Wireless networking, LAN, WAN, MAN, Security of the network, Fire-walls, Network Applications Information Technology: Concepts of client Server Architecture, Concept of search Engine, Database search engines. Introduction to Internet Introduction to Word, Powerpoint and Excel Introduction to Bioinformatics: History of Bioinformatics, Genome sequencing projects, Human Genome Project, Applications of Bioinformatics. Introduction to databases, Type and kind of databases, Applications and limitations. Literature Search Databases, Nucleic acid and protein databases, Animal and plant databases, Ensembl Genome project TIGR database, Biotechnological databases, Motifs and Pattern Databases, Databases for species identification and classification, Structural databases. Database Retrieval and deposition systems. Web tools and resources for sequence analysis: Pairwise and multiple sequence Alignment, Sequence similarity search: BLAST, Pattern recognition, motif and family prediction, Restriction map analysis, primer design, Gene prediction, Phylogenetic Tree, Protein structure prediction and visualization.

BIO-IIIM-1003

Basic Chemistry Thermodynamics Solutions and Ions Chemical bonding and molecular structure Chemical Kinetics Stereochemistry Introduction to drug discovery (Medicinal chemistry approach) Drug target, discovery and development (forward and reverse approach

BIO-IIIM-1004

Research Methodology, Communication/ethics/safety Philosophy and structure of scientific thoughts, Objective and Motivation of Research,

Final Draft

Meaning of the Research, What constitutes a research topic? How to select a research topic?, Importance of literature review, Selection of appropriate methodology, Collection of data, Interpretation of data, Writing research paper, Paper presentation in scientific conference, Statistical methods, Importance of documentation, Procedure for Hypothesis Testing, Values and Ethical Problems, Criteria of Good Research, Good laboratory practice, Chemical, Radioactive and Biological safety: Possible hazards and precautionary measures; do and don’ts upon exposure Research methodology, communication, ethics, safety Asking the right questions: Originality, Depth, Precision can co-exist Formulating and refining the hypothesis: Those who do not learn from the past are condemned to repeat it Study design: Recognizing and minimizing bias Experiment design: Sometimes less is more and the importance of controls Good lab practices: Record keeping, organizing data, organizing the lab space Data interpretation; objectivity, quantification, double blind studies and necessity of statistics Comunicating your data:writing up your research Comunicating your data: presenting your findings Radiation safety Chemical and Biosafety Intellectual property rights What is ethics, the different interpretations & historical instances of unethical science Case studies: Data fraud/ plagiarism and Human Ethics violation

Final Draft

200 level courses Course number

Course Content

BIO-IIIM-2001

Biotechniques and Instrumentation (compulsory) Principles and applications of centrifugation, spectrophotometery, fluorometery, densitometery, electrophoresis, PCR & RTPCR, blotting, immunoassays, flowcytometry, DNA sequencing & fingerprinting, Chromatography (GLC, HPLC, HPTLC, GCMS, LCMS), polarimetery, elemental analysis, NMR spectrometry, Mass spectrometry, Microscopy (Simple, electron and confocal), in vivo imaging, MALDI/TOF, Microarray,

BIO-IIIM-2004

Biology of Infection Host-microbe interactions Normal microbial flora of human body and their interaction with the host, Infection and infectious process and routes of transmission, Methods of transmission and role of vectors (Mosquitoes, Sand fly) Description and pathology of bacterial diseases Infections caused by Gram negative bacteria, Infections caused by Gram positive bacteria, Mycobacterium tuberculosis Description and pathology of fungal diseases Infections caused by candida spp, Infections caused by filamentous fungi Description and pathology of parasitic infections Infections caused by protoza, Infection caused by helminthes General properties of viruses Structure and replication of DNA and RNA viruses, Virus-host interactions, Detection and Cultivation of viruses Description and pathology of viral infections Infections caused by Pox viruses, herpes viruses, myxo and paramyxo viruses, adenoviruses and other respiratory viruses, hepatitis viruses, HIV virus Principles of chemotherapy Best in class antibacterial and anti-fungal agents, Drug resistance in bacteria and fungi, Best in class anti-protozoal agents and protozoal drug resistance, Best in class anti-viral agents Immunology Innate and acquired immunity, Components of immune system, T-cell subsets and surface markers, Antigen-antibody interactions, Types of hypersensitivity reactions, autoimmune disorders and their underlying molecular mechanisms, Immunoprophylaxis- Vaccines Techniques in diagnostic microbiology Immunological techniques, Serological techniques, Nucleic acid techniques

BIO-IIIM-2009

Plant-Microbe Interaction Introduction to plant microbe interactions Significance of plant diseases and pathology , Types of plant-microbe associations (pathogenic– bacteria, virus, fungi, and symbiotic) , Mechanisms of variability in pathogens, pathogenicity genes and mechanisms in pathogenic bacteria, biotrophic and necrotrophic fungi, Virus and Viroid genes involved in pathogenicity , Types of plant resistance to pathogens (R gene resistance, quantitative and monogenic), basal and induced defense mechanisms, pre-formed inhibitors of pathogens, gene for gene interaction in plant defense, , Systemic Acquired Resistance ( SAR ) and Induced Systemic Resistance ( ISR ), Recognition mechanism and signal transduction during plant - pathogen interaction Bacterial pathogenesis and mutualism Bacterial colonization of roots and leaves, Hydrolytic enzymes, Toxins and Secretion systems, Hypersensitive Response (HR) and eXchange Reaction (XR), Pathogenecity and avirulence factors, Microorganisms and rhizosphere microcosm dynamics, Signaling in Rhizobia-Legume symbiosis

Final Draft

Viral pathogenesis Viral infection, gene expression and replication, Host resistance against viruses, Gene silencing, VIGS and viral suppressors of RNAi Fungal Pathogenesis and Mutualism Fungal Pathogenesis: An overview , Fungal pathogenecity and virulence factors, Fungal toxins, Arbuscular mycorrhizal fungi, Endophytic Fungi and their secondary metabolites Case studies in Plant-Microbe Interactions Agrobacterium & crown gall disease: molecular responses, chemical cross-talk and biotechnological importance, Rice-Magnaporthe grisea pathosystem, Arabidopsis thaliana – Xanthomonas compestris model Relevance to Drug Discovery Program Production of pharmacologically active secondary metabolites in response to biotic stress, Fungal endophytes as source of interesting bioactive molecules, Crown gall and human cancers, similar themes, similar cures? BIO-IIIM-2011

Molecular Therapeutics General pharmacology, phytopharmacology, drug receptor interactions, in-vitro and in-vivo bioassays in drug discovery and development

BIO-IIIM-2012

Cell Signaling Cell-to-cell signaling: Signal transduction; Classification of intercellular communication; Signaling pathways from the plasma membrane to the nucleus; Unicellular and multicellular organism cell signaling; Signaling in plants: Similarities/Differences with mammalian system; ER-golgi signaling in unfolded protein responses; Second messengers & Calcium/calmodulin; cAMP in cell communication; Phosphatidylinositol-derived second messengers; Nuclear receptors; Identification and characterization of receptors; Pharmacological and molecular classification of receptors; GTPase switch proteins, protein kinases, adapter proteins; G-protein-coupled receptors, Receptor tyrosine kinases & mitogen-activated protein kinase cascade(s); Transcription factors as signal transducers; Kinase -proteases crosstalk in cellular signalling; Extracellular signaling molecules and their action; Signaling cascades in excitotoxicity with special reference to GABA & AMPA receptors; Special properties of the NMDA glutamate receptor; Signaling and endocrine functioning; Insulin signaling pathways; Hormone-regulated transcription factors; Antagonists at the nicotinic acetylcholine receptor; Cell fate determination: Role of growth factors; Pathways involved in cell differentiation and self renewal in mammalian system; Apoptotic signaling versus normal survival signalling; Major signaling cascades in cancer (β-catenin, Wnt signaling etc); Signaling involved in global protein translation and cancer progression; Hypoxic or stress mediated signaling in tumor microenvironment; Signaling mechanisms of neurodegeneration and neuroprotection; Signaling mechanisms of inflammation; Modulation of signaling pathways in stem cell by small amolecules.

BIO-IIIM-2013

Chemical biology Basics in chemical biology How small molecules have been used to probe and modulate signal transduction pathways and major metabolic pathways, Signal transduction , Protein translation, Stressing mechanistic aspects of protein synthesis and folding in vivo, Cell Biology, Enzymes overview , Enzyme kinetics and enzymatic reactions Chemistry of Natural products NPs sources, classification, Isolation, identification, characterization or structural elucidation of the NP compounds Organic Synthesis Synthetic design, retro-synthetic analysis, synthetic methods, total syntheses Basics in spectroscopic techniques and stereochemistry Basics in Medicinal Chemistry and Bio-informatics Bio-informatics: Software based drug designing Medicinal Chemistry: Hit identification, lead generation and lead optimization by medicinal chemistry approach for drug discovery Target based drug design

Final Draft

Introduction to Drug discovery Stages of drug discovery NCEs, IND filing, NDA, etc Drug targets Discovery & development

Final Draft

300 level courses Course number

Course Content

BIO-IIIM-3002

Cancer biology Introduction to cancer, Biochemical strategies for cancer detection: Recent technological advancements, Properties, cancer types and their prevalence: Relevant scientific associations, Important tumor markers: Potential role in search of novel markers in various cancers, Developments in oncogenic enzymology in understanding the cancer biology, Adhesive interactions: Biochemical toolbox of cancer cells, Cancer development & metastasis: Molecular Basis, Repetitive elements & genomic instability: Role in pathogenesis of cancer, Histone acetylases/deacetylases in cancer: Role in gene expression, Mutational analysis in cancer: Consequences & origin , Epigenomic basis of cancer: Role in initiation and development, Understanding of posttranslational modifications in cancer cell, Angiogenesis and malignancy, Stem cell biology & cancer, Important signaling pathways of cancer, DNA methylation machinery pathways for identification of new biomarkers , Carcinogenesis and apoptosis: Modulation by small molecules , Translation machinery and cancer progression , Stem cell fate determination: Importance of growth factors, Role of Histopathological & Immunocytochemical techniques in cancer, Aggressive tumors: Gleason score in pathology, Gene silencing and tumorgenesis, RNAi technology in cancer treatment, Pathways involved in cell differentiation/ immortalization in cancer, Initiation and propagation of cancer cells in cell culture systems: Evaluation of important properties and their relevance with human biology, Hypoxia/ tumor cell microenvironment and metabolic pathways in cancer, Pharmacokinetic and Pharmacodynamic parameters of important anticancer drugs, Discovery and clinical validation of a targets in cancer, Tools, techniques & important parameters involved in screening new bioactive(s) as possible anticancer agent(s), Cell cycle regulators: Role as therapeutic targets in cancer, Diseased and cancerous cell: Morphological and microscopic features, Orthotropic and xenografted models: Importance and their limitations in understanding cancer, Human tissue recombination models in cancer: Laser capture dissecting

BIO-IIIM-3381

Pharmacological screening, Hit identification and mechanism of action Introduction to drug development , Selection of disease and test material, Drug Discovery using natural products , Drug Discovery using synthetic compounds , In silico biology in Drug development , Identification and validation of drug target , Assay development, Screening and Identification of lead compounds, Lead optimization and Formulation Development: Dr. P. N. Gupta , Mechanism of action , Case studies in Drug Discovery, IPR issues and Legal Affairs , IND filing and Regulatory guidelines

BIO-IIIM-3382

ADME Pharmacokinetics and pharmacodynamics; Bioavailability; Drug Disposition: Absorption, Distribution; Drug Disposition: Metabolism, Elimination;

BIO-IIIM-3383

Toxicology Principle of toxicology; Preclinical toxicology and mutagenesis; Systemic toxicology and teratology; Regulatory Pharmacology

Final Draft

IITR 100 level courses Course number BIO-IITR-1001

Course Content

Biostatistics Summarization of Data: measures of center, dispersion, skewness Dependence of variables: Correlation, linear regression, logistic regression Basic probability distributions: Binomial, Normal, Chi-squares. Estimation of parameters: method of moments, maximum likelihood Testing of hypotheses: (a) parametric tests: t-test, z-test, chi-squares test, ANOVA (b) non-parametric tests: Mann-Whitney, Kruskal Wallis, Kolmogorov-Smirnov

BIO-IITR-1002

Computation/bioinformatics Computers: Introduction, Evolution and Classification of computers. Fundamentals of computing. Bit and Byte, Introduction to types of Hardware and Software. Components of Computer. Introduction to operating systems. Introduction to Computer Viruses. Network: Introduction. Network structure and architecture, Hierarchical networks, Ethernet and TCP/IP family of protocols, transport protocol design. Types of network, Topologies of network, Router, Switch, Data Communication, Concept of Wireless networking, LAN, WAN, MAN, Security of the network, Fire-walls, Network Applications Information Technology: Concepts of client Server Architecture, Concept of search Engine, Database search engines. Introduction to Internet Introduction to Word, Powerpoint and Excel Introduction to Bioinformatics: History of Bioinformatics, Genome sequencing projects, Human Genome Project, Applications of Bioinformatics. Introduction to databases, Type and kind of databases, Applications and limitations. Literature Search Databases, Nucleic acid and protein databases, Animal and plant databases, Ensembl Genome project TIGR database, Biotechnological databases, Motifs and Pattern Databases, Databases for species identification and classification, Structural databases. Database Retrieval and deposition systems. Web tools and resources for sequence analysis: Pairwise and multiple sequence Alignment, Sequence similarity search: BLAST, Pattern recognition, motif and family prediction, Restriction map analysis, primer design, Gene prediction, Phylogenetic Tree, Protein structure prediction and visualization.

BIO-IITR-1003

Basic Chemistry Thermodynamics Solutions and Ions Chemical bonding and molecular structure Chemical Kinetics Stereochemistry Introduction to drug discovery (Medicinal chemistry approach) Drug target, discovery and development (forward and reverse approach

BIO-IITR-1004

Research Methodology, Communication/ethics/safety Philosophy and structure of scientific thoughts, Objective and Motivation of Research,

Final Draft

Meaning of the Research, What constitutes a research topic? How to select a research topic?, Importance of literature review, Selection of appropriate methodology, Collection of data, Interpretation of data, Writing research paper, Paper presentation in scientific conference, Statistical methods, Importance of documentation, Procedure for Hypothesis Testing, Values and Ethical Problems, Criteria of Good Research, Good laboratory practice, Chemical, Radioactive and Biological safety: Possible hazards and precautionary measures; do and don’ts upon exposure Research methodology, communication, ethics, safety Asking the right questions: Originality, Depth, Precision can co-exist Formulating and refining the hypothesis: Those who do not learn from the past are condemned to repeat it Study design: Recognizing and minimizing bias Experiment design: Sometimes less is more and the importance of controls Good lab practices: Record keeping, organizing data, organizing the lab space Data interpretation; objectivity, quantification, double blind studies and necessity of statistics Comunicating your data:writing up your research Comunicating your data: presenting your findings Radiation safety Chemical and Biosafety Intellectual property rights What is ethics, the different interpretations & historical instances of unethical science Case studies: Data fraud/ plagiarism and Human Ethics violation

Final Draft

200 level courses Course number

Course Content

BIO-IITR-2001

Biotechniques Affinity chromatography, gel filtration chromatography, high performance liquid chromatography (HPLC), PCR, restriction fragment length polymorphism (RFLP), Agarose gel electrophoresis, Polyacrylamide gel electrophoresis (PAGE), two dimensional gel electrophoresis, MALDI-TOF, LCMS/ MS, ELISA, RNAi, blotting techniques, Microarray technology. Separation and characterization of biopolymers, UV/Visible Spectrophotometry, Co-immunoprecipitation, transfection, transgenics, Light microscopy, Fluorescence microscopy, fixation and staining techniques, Transmission electron microscopy (TEM), Scanning, electron microscopy (SEM), flow cytometry.

BIO-IITR-2003

Biology of Inheritance Mutagenesis, DNA repair and applications of mutagenesis; Mechanisms of gene transfer including conjugation & transduction, and Recombination & mapping in prokaryotes; Applications and uses of transposable elements, gene regulation, virulence functions and horizontal gene transfer. Mendelian principles; Segregation and linkage; Recombination and mapping in eukaryotes; Gene interactions, forward and reverse genetics; chromosome rearrangements and their effects on gene expression.

BIO-IITR-2008

Xenobiotic Interaction and response Introduction to the discipline of toxicology and basic concepts essential for understanding the action of exogenous agents on biological systems; Principles underlying the absorption, distribution, metabolism, and elimination of chemicals. Toxicokinetics, specific classes of toxic responses, and experimental methods used to assess toxicity; ethics in toxicological studies, Regulatory toxicology.

BIO-IITR-2012

Cell Signalling [Introduction, historical perspective, classification]; Growth/ Differentiation/Apoptosis Leukocyte integrin/endothelial cells interaction; Receptorligand interactions/Cytokine signaling/G-protein-mediated signalling; Growth hormones/Receptor-mediated signalling; Neuronal signalling/Signaling in stem cells; Ion channels; Signaling in immune cells; Signaling aberration & Diseases [cancer, cardiovascular, diabetes]; Gene expression [Relevant transcription factors]; Cell regulatory mechanism [Role of p53, pRb, PTEN]; Nuclear Receptors & Signal transduction; Signal transduction pathways [Ras-MAPK, PI3K-AKT, p53, pRb; TGF-β, JAK-STAT, cAMP, Notch, Hedgehog and Wnt]; Signaling Crosstalks; Small group discussion [Literature review].

BIO-IITR-2022

Stem cells: Basics and future applications Stem cells: the concept, types, development and plasticity; Isolation, purification, characterization, cultivation and differentiation of stem cells in laboratory conditions; Stem cell niche, homing, and migration; Genomics and proteomics of stem cells; Role of epigenetics to decide the fate of stem cells; Cellular and nuclear reprogramming to develop induced pluripotent stem cells; Therapeutic prospects of stem cells; Stem cells and biomaterial scaffolds for constructing tissues and drug delivery; Cancer stem cells: immunologic targeting; Applications of stem cells in toxicology studies; Ethical issues associated with stem cells.

BIO-IITR-2416

System Immunology System Immunology: Integrated perspective on entities and players participating at different system levels to the immune function; Antibody Structure, Antigenantibody interactions, Binding Sites, Affinity (Mathematical derivation) Avidity (Mathematical derivation); Major histocompatibility complex (organisation, function, inheritance & self restriction); Infection & Immunity (emphasis on TB, AIDS & Influenza); Signalling in immune cells and signalling aberration; Molecular Biology of

Final Draft

CMI and delayed reactions; Complement System (different components, functions, regulation and biological consequences); Allergy and Inflammation, IgE (Hypersensitive reactions & Mediators); Organ specific and systemic Autoimmunity; Transplantation (immunologic basis and clinical manifestation of graft rejection; immune tolerance and xenotransplantation) Practicals Isolation of Lymphocytes from blood and leukocyte counting; In vitro lymphocyte culture; PFC assay, HA titre; Quantitative analysis of cytokines by Sandwich ELISA; PCR based Cytokine gene expression

Final Draft

300 level courses Course number

Course Content

BIO-IITR-3001

Seminar History of science with emphasis on Indian contribution: Seminar by students.

BIO-IITR-3012

Environmental Toxicology Environmental Toxicology in present and future perspective; Environmental hazards (physical, chemical and biological aspects); Origin, sources and types of toxicants/pollutants; Dispersal/movement of toxicants in environmental compartments; Conventional and alternate models in toxicity assessment; Assessment of toxicity of pollutants; Absorption, distribution and storage of toxicants; Dose response relationships; Biotransformation and elimination of toxicants; Mechanisms of action of toxicants; Gene-environment Interactions Pollution monitoring and Risk assessment; Tools for detection; Fate and transport Hazardous waste management; Regulation, approaches and strategies; Mitigation of environmental pollutants; Physico-chemical and biological processes Practicals Xenobiotics exposure/effect assessment using alternate animal models; Case histories/studies and new concepts or topics will be interactively discussed; Case studies: real-life sites/ecological settings/industry in and around Lucknow

BIO-IITR-3416

Model systems in Toxicological Research In vitro: Basics and principles of cell and tissue culture; primary cell cultures, cell lines, stem cells. In vivo: Bacteria, Yeast, Paramecium, Tetrahymena, Caenorhabditis elegans, Drosophila, Daphnia, Tubifex, Snail, Zebrafish, mammalian models. In silico: Basics of QSAR and modeling of macromolecules

BIO-IITR-3417

Food & Chemical Toxicology Food and Chemical Toxicology: Uniqueness and Complexity; Toxicity of Metals; Toxicity of Pesticides; Methods for detection and analysis of metals and pesticides in different matrices; Principles of drug induced toxicity; Cosmetic Toxicity; Protocols for identification of protein allergens: mucous membrane test, patch test; Nutraceuticals; Sea Food: Safety issues; Pl Toxins & Phytomedicine; Preparation and characterization of herbal extracts; Genetically Engineered Food/Crops; Food Contaminants and Adulterants; Analysis of food additives, contaminants and adulterants; Food Borne Pathogens; Toxicity of Tobacco Related Products; Protocols for assessment of genotoxicity and carcinogenicity: Food Poisoning and Food Safety: Prevention of Food Adulteration Act

BIO-IITR-3418

Target organ toxicity Overview: Types of injury that may be produced in specific mammalian organs and organ systems by exposure to chemical toxicants; Neurotoxicity and its mechanisms: Concepts in neuropharmacology and neurophysiology; Neurogenesis; Neuro-behavioral toxicology; Chemical induced neurodegeneration and neuroprotection/ neuroregenration; Hepatotoxicity: Overview; Effect of xenobiotics on liver; Regulatory mechanism involved in hepatotoxicity; Nephrotoxicity: Renal structure and function; Chemical induced renal injury; Pulmonary toxicity: Structure and function of the respiratory system with emphasis on lungs; Systemic lung injuries; Immunotoxicity: Basics of the immune system; Mechanisms of immunotoxicity; Immunosensitization and allergy; Endocrine and reproductive toxicity: Teratogenicity; Reproductive organs and chemicals affecting reproduction; Endocrine system and chemical induced endocrine disruption

BIO-IITR-3419

Nanomaterial Toxicology Basics of nanotechnology: Synthesis and characterization of engineered nanomaterials (ENMs); Sol gel, biological and ball milling methods for synthesis of ENMs and

Final Draft

characterisation using electron microscopy (TEM, SEM), dynamic light scattering (DLS) and confocal microscopy; Safety assessment of ENMs – methods and challenges: Methods for assessment of toxicology of ENMs; preparation of nano-suspensions; exposure paradigm, cellular uptake, absorption and distribution; in silico approaches for macromolecule interaction with ENMs; Mechanism of toxicity of ENMs: Effect of size, shape and surface chemistry on cellular responses (oxidative stress, cytotoxicity, genotoxicity, immunotoxicity etc); Ecotoxicity of ENMs: Models and methods used for ecotoxicity assessment of ENMs; life cycle analysis of ENMs; Safe handling of ENMs and their disposal. Practical Preparation of nano-suspensions and their characterization Cellular uptake using flow cytometer Cytotoxicity assessment for ENMs

BIO-IITR-3420

Chemical Carcinogenesis and Chemoprevention Chemical Carcinogenesis: Past, Present and Future, Genetic and Epigenetic Mechanism of Carcinogenesis, Models, Mechanism and Etiology of Cancer, Role of Oncogenes in Cancer Development, Cell Transformation and Apoptosis, Mutation and Cancer, Targeted Drug Delivery in Cancer Chemotherapy.

BIO-IITR-3421

Neurotoxicology Introduction- Basic elements of central, peripheral and autonomic nervous system; Organization of CNS- Brain & Spinal Cord; Anatomy of Neuron and neuronal supportive cells – Glial cells; Physiology of Neuron –generation and propagation of AP; Central Neurotransmitters & Receptors: Catecholamines (Epinephrine, Norepineprine & Dopamine), 5-Hydroxytrytamine (5-HT), Acetylcholine, Histamine Inhibitory Amino Acid (GABA, Glycine & Benzodiazepines) Excitatory Amino Acid (Glutamate); Neurotoxicology: Basic concepts and principles; Developmental neurotoxicology; Neurotoxicology of metals, pesticides, solvents, monomers, natural agents; Neurobehavioal approaches to screen neurotoxicity; Assessment of neurotoxicity involving neuromorphological, neuropathological, neurophysiological and neuroimaging approaches; Assessment of neurotransmitters and neurotransmitter receptors: Usefulness in neurotoxicology; In vitro and in vivo models in neurotoxicology; Clinical neurotoxicology : basic principles; Neurotoxins and neurodegenerative disorders; Risk assessment and use of biological markers for neurotoxicity; Neuroprotective and regenerative approaches

BIO-IITR-3422

Genes and environmental diseases An introduction to abiotic stress, effect of temperature and pollutants on the gene expression, recent advances in organismal responses to abiotic stresses; Current tools to measure environmental exposures/pollutants; Effect of environment and methods to detect genetic variation; Genes, environment and neurodegenerative diseases; Genes, environment and cancer; Genes, environment and asthma and allergy; Genes, environment and reproductive diseases

Final Draft

IMTECH 100 level courses Course number BIO-IMT-1001

Course Content

Biostatistics Summarization of Data: measures of center, dispersion, skewness Dependence of variables: Correlation, linear regression, logistic regression Basic probability distributions: Binomial, Normal, Chi-squares. Estimation of parameters: method of moments, maximum likelihood Testing of hypotheses: (a) parametric tests: t-test, z-test, chi-squares test, ANOVA (b) non-parametric tests: Mann-Whitney, Kruskal Wallis, Kolmogorov-Smirnov

BIO-IMT-1002

Computation/bioinformatics Computers: Introduction, Evolution and Classification of computers. Fundamentals of computing. Bit and Byte, Introduction to types of Hardware and Software. Components of Computer. Introduction to operating systems. Introduction to Computer Viruses. Network: Introduction. Network structure and architecture, Hierarchical networks, Ethernet and TCP/IP family of protocols, transport protocol design. Types of network, Topologies of network, Router, Switch, Data Communication, Concept of Wireless networking, LAN, WAN, MAN, Security of the network, Fire-walls, Network Applications Information Technology: Concepts of client Server Architecture, Concept of search Engine, Database search engines. Introduction to Internet Introduction to Word, Powerpoint and Excel Introduction to Bioinformatics: History of Bioinformatics, Genome sequencing projects, Human Genome Project, Applications of Bioinformatics. Introduction to databases, Type and kind of databases, Applications and limitations. Literature Search Databases, Nucleic acid and protein databases, Animal and plant databases, Ensembl Genome project TIGR database, Biotechnological databases, Motifs and Pattern Databases, Databases for species identification and classification, Structural databases. Database Retrieval and deposition systems. Web tools and resources for sequence analysis: Pairwise and multiple sequence Alignment, Sequence similarity search: BLAST, Pattern recognition, motif and family prediction, Restriction map analysis, primer design, Gene prediction, Phylogenetic Tree, Protein structure prediction and visualization.

BIO-IMT-1003

Basic Chemistry Thermodynamics Solutions and Ions Chemical bonding and molecular structure Chemical Kinetics Stereochemistry Introduction to drug discovery (Medicinal chemistry approach) Drug target, discovery and development (forward and reverse approach

BIO-IMT-1004

Research Methodology, Communication/ethics/safety Philosophy and structure of scientific thoughts, Objective and Motivation of Research, Meaning of the Research, What constitutes a research topic? How to select a research

Final Draft

topic?, Importance of literature review, Selection of appropriate methodology, Collection of data, Interpretation of data, Writing research paper, Paper presentation in scientific conference, Statistical methods, Importance of documentation, Procedure for Hypothesis Testing, Values and Ethical Problems, Criteria of Good Research, Good laboratory practice, Chemical, Radioactive and Biological safety: Possible hazards and precautionary measures; do and don’ts upon exposure Research methodology, communication, ethics, safety Asking the right questions: Originality, Depth, Precision can co-exist Formulating and refining the hypothesis: Those who do not learn from the past are condemned to repeat it Study design: Recognizing and minimizing bias Experiment design: Sometimes less is more and the importance of controls Good lab practices: Record keeping, organizing data, organizing the lab space Data interpretation; objectivity, quantification, double blind studies and necessity of statistics Comunicating your data:writing up your research Comunicating your data: presenting your findings Radiation safety Chemical and Biosafety Intellectual property rights What is ethics, the different interpretations & historical instances of unethical science Case studies: Data fraud/ plagiarism and Human Ethics violation

Final Draft

200 level courses Course number BIO-IMT-2001

Course Content

Biotechniques and Instrumentation (compulsory) Instruments - Acquaintance and handling of instruments (For example: weighing balance, pH meter, centrifuges, HPLC, FPLC, PCR machine etc) Techniques in Biology - Handling of microbes and their basic characterization, Taxonomic characterization microbes and biochemical tests for characterization of a bacterium by Gram staining, MRVP test, Lactose fermentation, fatty acid profiling etc. Recombinant DNA technology - Concept of cloning, Plasmid DNA isolation, bacterial transformation with plasmid DNA, restriction digestion etc. - DNA sequencing: scope, application and troubleshooting. Protein expression and purification (concept of chromatography) Biochemical/Biophysical techniques MALDI and its application. Steady state fluorescence spectroscopy and its use Protein-DNA interaction: Electrophoretic mobility shift assay and use of phosphoimager - X-ray crystallography: Crystallization of proteins. Application of NMR. Cell Biology tools - Use of electron microscopy - Applications of confocal microscopy. Use of flowcytometer. Tools and techniques of Fermentation - Animal handling

BIO-IMT-2002

Biology of Macromolecules Protein conformation - Protein crystallography - Protein-Protein interaction – enzymes Protein-Nucleic acids interaction - Cryo-EM – SAXS - Protein structure analysis - Macromolecular complexes - Membrane proteins - Classification of proteins - Structural bioinformatics

BIO-IMT-2003

Biology of inheritance Classical and molecular genetics of bacteria - Molecular genetics and genome wide approaches in yeasts - Nucleic acids structure and topology - Central dogma and concepts on DNA transactions – Replication - Transcription & Transposition - DNAprotein contact probing - Molecular mechanisms and dynamics of replication Control - Licensing mechanisms – Telomeres - Transcriptional regulation and gene expression - Genetic Recombination - Chromatin structure and remodeling - The mechanisms of RNA interference - Ribozymes and riboswitches - Genome imprinting

BIO-IMT-2004

Biology of infection Evolution of Bacterial Pathogens: a) Genetic basis of Virulence b) Techniques involved in identification of virulence genes c) Population Genetics of pathogen Glycobiology paradigm in host-pathogen interactions. Delivery of Virulence factors through various transporter systems - Regulation of Virulence gene expression : a) One and Two component signal transduction, b) Quorum sensing mediated virulence expression c) Environmental signals (such as pH, osmotic stress, temperature, antibiotics, NO, host factor etc) mediated virulence traits Molecular pathogenesis of Bacterial pathogens, Protozoan pathogens (Malaria) and Fungal pathogens (Candida albicans). Model systems to understand the function of unique virulence factors

BIO-IMT-2005

Genomics: Information flow in Biological Systems Introduction - Next-generation sequencing technologies - Strategies for large scale DNA sequencing - Library preparation and sequencing of a genome -

Final Draft

Computational assembly of a genome – Information sources for genomics – Principles of sequence analysis - Annotation and analysis of a genome – Evolutionary concepts in genomics - Genomes and the protein universe - Genome properties - DNA Repeats in genomes – Phylogenomics - Introduction to comparative genomics - Comparative genomics - Population genetics - Case study – genomics approach – Metagenomics - Analysis of gene expression

BIO-IMT-2006

Protein Science and Proteomics Protein Spectroscopy - Design Principles of Protein molecular machines Translational and transcriptional - Unwinders and Degraders - Filters and Transporters - Post-translation modification - Therapeutic protein - Protein vehicles - Proteomics - Glycobiology - Nano-biotechnology

BIO-IMT-2007

Systems Biology Introduction - Mathematical Tools for systems biology - Physico-chemical understanding of the system - Building kinetic and statistical mechanical model of biological processes - Modeling of gene expression - Systems biology of signal transduction - Autoregulation and kinetic proof readings in biology - Modeling of biological processes at multi-level

BIO-IMT-2012

Cell Signaling Cell Signaling research – a historical perspective - Cell Signaling hardwires – kinases, phosphatses, GPCR, Small GTPase – Cell Signaling in prokaryotes – Twocomponent system – environment sensing, Nutrient sensing and stress response – quorum sensing and social behavior in prokaryotes – Cell signaling in Fungi – Pheromone response pathway, nutrient sensing, osmosensing signal transduction pathway – Cell signaling softwares – Control mechanisms in cell signaling – System level and genome scale understanding of signaling pathways – Cell signaling in Metazoan – Differentiation and disease, cell communication – Methods in cell signaling research – kinase, phosphatase, GTPase etc assay – use of inhibitors and non-hydrolysable analogs – use of dominant and recessive mutants – analog sensitization – multiplex western blotting – protein-protein and proteinligand interactions – FRET and FRAP analysis – Applications of Fluorescence microscopy in cell signaling research

BIO-IMT-2013

Chemical Biology Organic Chemistry and Biology - Chemical Biology and Computers - Lipid and Sugar Chemistry - Drug Discovery through screening - Enzyme ConformationActivity

BIO-IMT-2020

Molecular and Cellular Mechanisms of Defence Introduction to Immunology - Historical perspective of immunology - Immune organs - Immune cells - Innate immunity - Adaptive immunity - Cellular Immunology - T and B cell biology, antigen presenting cells, Major Histocompatibility Complex (MHC) - Signaling and effectors of immune system Immunoglobulins, cytokines, chemokines and cell signaling - Disease and immunity - Immunology of infectious diseases, cancer, autoimmune disorder and hypersensitivity-mediated diseases - Recent trends in immunology Reproductive immunology, immunodiagnostics and immunotherapy.

BIO-IMT-2025

Final Draft

Biodiversity

Universal tree of life: domains of life, bacteria, archaea and eukarya - Prokaryotic species concept: Characterization of prokaryotes – polyphasic taxonomy Overview of microbial diversity, methods, and limitations in studying microbial diversity - Molecular phylogeny : different types of genes used for phylogenetic studies and their importance - Metagenomics and its applications - The world of fungi : Diversity, taxonomy, classification, preservation and their maintenance Microbial life in the biosphere –interactions between the microorganisms and ecosystem, adaptations to the extreme environments - Phototrophic Bacteria: Methods of cultivation and applications - Microbial diversity – bio-prospecting, applications and economic importance - Anaerobic microbes – methods to cultivate the anaerobic microorganisms and their metabolism

BIO-IMT-2026

Bioinformatics Biological Databases - Database- introduction and definition. Primary, secondary and tertiary databases. Type and kind of databases. Literature (PUBMED and MEDLINE). Nucleic acid and protein databases (GenBank, EMBL, SWISS PROT, UNIPROT etc.). Plants and Animal databases (Ensembl Genome project, Flybase, Maize GDB). Structural databases- PDB, PDBsum, NDB, CATH, SCOP etc. Motifs and Pattern Databases- PROSITE, Pfam, etc. RNA databases: RNABase etc. Carbohydrates and lipid databases- GlycoSuiteDB, LIPIDAT etc. Database Retrieval and deposition systems- SRS, Entrez, Bankit, etc. and AutoDep. Protein-Protein Interaction Networks and databases- DIP (Database of Interacting Proteins), BIND - Biomolecular Interaction Network Database, Yeast Interaction Database etc. siRNA/miRNA resources. File formats- GenBank, EMBL, fasta, free format etc. Alignment of Sequences - Sequence alignmentintroduction and concepts; Sequence comparison using DOT matrix. Scoring matrices (Identity, Chemical, Substitution- PAM, BLOSUM); Local and global alignment concepts. Dynamic programming (Needleman-Wunch, Smith-Waterman algorithm). Similarity and percent identity score (open, extended gap penality). Multiple sequence alignment-introduction and concepts. Types of multiple sequence alignment techniques. Description of major software (MSA, CLUSTALW, PILEUP). Database Scanning and Sequence similarity searches. Algorithm of FASTA. Description of BLAST algorithm. Various BLAST programs (e.g., BLASTP, BLASTN). Concept of iterative search (PSI-BLAST and PHI-BLAST). Application of PSSM profile. Sequencing and Annotation of Genomes - Introduction to genomes. Sequencing techniques. Sequencing of whole genomes. Next Gen Sequencing. Assembling of Genomes from Short Reads. Concept of Metagenomics. Types of repeats and repeat finding techniques. Structure of genes. Prediction of gene in prokaryotic and eukaryotic genomes. Prediction of promoter prediction in E.coli and in eukaryotes. Description of major gene prediction methods. Comparison of genomes. Genome projects and sequence archive databases. Phylogenetic Analysis - Evolutionary analysis. Relationship of phylogenetic analysis to sequence alignment. Genome complexity. Concept of evolutionary trees. Methods-maximum parsimony method, distance methods, the maximum likelihood approach. Sequence alignment based on evolutionary model. Reliability of phylogenetic predictions. Complications from phylogenetic analysis - Protein Structure Analysis - Protein Structure –Introduction. Protein Structure analysis. Secondary structure assignments (DSSP). Protein Structure Comparison and alignment. Distance Matrices. Maximum Common Sub-graph Algorithm (PROCOR). Structural alignment algorithms (CE, VAST, DALI, SSAP etc.) - Prediction of Protein Structure - Protein structure prediction-concepts. Use of sequence patterns for protein structure prediction. Prediction of protein secondary structure from the amino acid sequence- Secondary structure Prediction methods: First, second, third and fourth generation methods like CHOU-FASMAN, GOR; Nearest neighbor methods like GOR-IV etc., Neural network methods like PHD, PSIPRED, JPRED. Hidden Markov Models like HMMER. Concepts, algorithms and their limitations. Evaluation of success of structure predictions. Benchmarking, CASP, CAFASP, EVA etc.- Protein three dimensional structure prediction- Introduction. Homology Modeling (method- SWISS-MODEL, MODELER, Fold recognition method3-D PSSM, SAM, I-TASSER etc. abinitio method –Introduction and concepts Basic principle 2D and 3D graphics and use of molecular graphics packages (e.g.

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Rasmol, MOLMOL, Chimera, Pymol, spdbviewer), Building small molecules using chemical information. Structure Visualization techniques (Software & Hardware) RNA Structure Prediction - Importance of RNA structure. Features of RNA secondary structure. Development of prediction methods. Self complementary regions in RNA sequences. Minimum free energy method. MFOLD and use of energy plots. Covariation analysis in RNA sequences and its use in structure prediction. Mutual information content. Limitations of prediction - Molecular Simulation and Docking - Introduction to Molecular Modeling. What are models used for? Areas of application – Single molecule calculation, assemblies of molecules, Coordinate Systems. Potential energy surface - Molecular structure and internal energy. Molecular Potential Energy function. Empirical force field. Sources of force field data. Examples of important force fields - Energy MinimizationConcepts. First derivative techniques: steepest descent and conjugate gradients, Second derivative techniques: Newton-Raphson, Global Optimization (simulated annealing) - Molecular dynamics- Introduction, Molecular dynamics using simple models, Dynamics with continuous potentials. Constant Temperature and constant dynamics, Conformation searching, Systematic Search. - Conformational Analysis: Systematic Methods, Random search methods, distance geometry - Principles and methods of docking. docking problem. Scoring functions. Macromolecular dockingConcept. Practice and limitations of Computer assisted drug discovery process Computer Aided Subunit Vaccine Design - Introduction to immunoinformatics. Concept of subunit vaccine: Endogenous and Exogenous antigen processing. Prediction of CTL epitopes (MHC Class I binders, Cleavage sites, TAP binders, Nonepitope MHC binders). Identification of T-helper epitopes and promiscuous MHC class II binders. Prediction of B-cell epitopes (linear and conformational epitopes). Role of innate immunity in adjuvant design; Integrative approach for epitope or peptide based vaccine – Microarray - Introduction, history and types of microarrays. Application of microarray. Affyemetrix Technology. Stanford/cDNA chip. Processing and analysis of images. Preprocessing of expression data. Normalization of data; Differential Gene expression. Expression based clustering of genes (Supervised, Unsupervised, K-means, Hierarchical). Prediction of function from expression data. Microarray databases.

BIO-IMT-2451

Final Draft

Biochemical Engineering Bio-reactions and bioreactors – Introduction to bioprocess engineering – interaction of chemical engineering – biochemistry and microbiology, cell growth and product formation kinetics – mammalian cell culture – biocatalysis – immobilization of cells and enzymes – types of reactors – mass transfer and heat transfer – asepsis and sterilization – scale up and scale down of bioprocesses – Downstream processing – Principles of choosing a separation/ purification process – Intracellular and extracellular product recovery methods – bioprocess synthesis.

300 level courses Course number BIO-IMT-3001

Course Content

Seminar Course (compulsory) History of science with emphasis on Indian contribution: Seminar by students

BIO-IMT-3004

Frontiers of Biology: Synthetic Biology Introduction to synthetic biology – Biobricks/parts, devices, systems – Peptide and protein building blocks for synthetic biology – reconstruction of genetic circuits, logic gates – application of synthetic biology – in medicine, energy, environment etc – Future perspectives – Major ongoing and international initiatives – Methods for large scale reconstruction of parts/ metabolic pathways

BIO-IMT-3005

Advanced Bioinformatics

Computer Software - Concept of LAMP (Linux, Apache MySQL and PERL) learning. Introduction to Linux. Installation of Linux; Basic and advance Linux commands. Editors (vi, emacs). Software installation and configuration; Introduction to Apache. Configuration of Apache. Launching of web site using Apache; Introduction of HTML. Development of web sites; Concept of common gateway interface (CGI). Concept of FORMS in HTML. Introduction to MySQL. Development of Databases using MySQL. Introduction to PERL. Example PERL programs. Handing FASTA files. Program for calculating amino or nucleotide composition of sequences – Algorithms - Algorithms and techniques used for developing programs for biological problems. Quantitative matrices. Introduction to Machine Learning Techniques. Artificial Neural Network. Support Vector Machine. Hidden Markov Model. Example-based leanings. Major Software for implementing algorithms (SVM_light; SNNS; HMMER; Weka). Introduction to R: Introduction to R. Installation of R. Description of R environment. Using R interactively. Getting help with functions. Assigning variables. Arrays and vectors. Functions on vectors. Using R commands from terminal. Reading data from files. Programming in R. - Bioinformatics Software for Annotation of Proteins Important of annotation of proteins. Classification of protein annotation methods. Protein Sub-cellular Localization (amino acid, dipeptide, split-amino acid composition). Prediction of Antigenic regions in proteins (motif, matrix and ANN based methods). Secondary structure prediction (probability, segment, evolutionary approaches). DNA/RNA interacting residues in proteins (binary, PSSM and composition based approaches).

(Note: This course is designed for students interested in research in the field of bioinformatics particularly in developing prediction and classification programs/web-servers. Equal number of theory and practical classes shall be taken up in this course.)

BIO-IMT-3-

Final Draft

Mycobacterium tuberculosis

451 Introduction to TB & A historical prospective of TB - Diagnosis of TB- development of Tuberculosis Vaccines - Treatment of tuberculosis-Drugs under development Experimental animal models of tuberculosis - Molecular evolution of Mycobacterium - Ultra-structure and Biochemistry of mycobacterial cell- Lipids of mycobacterium- Structure, biosynthesis and biological activity - Redox homeostasis in Mycobacterium - Latency of mycobacterium- An overview of latency and mechanisms involved in persistence - Hypoxia and NO-A window to persistence of mycobacterium - Mechanism of signal transduction in mycobacterium. Serine-threonine kinases and two component proteins of mycobacterium - Transcription machinery of mycobacterium-Sigma factors and their role in the virulence of mycobacterium - Experimental Genetics of Mycobacterium - Interaction of Mtb with macrophages - Immunopathology of TB

BIO-IMT-3452

Metagenomics Introduction to metagenomics, challenges, functional applications - A typical metagenomic study - eg.human distal gut microbiome Metagenomic library preparation and sequencing - Metagenomicassembly basics - Metagenomic gene identification, metabolic reconstruction - Genome variations, Detecting genome variations in metagenomic data, Quasi species detection Community and comparative metagenomics - Amplicon sequencing and Gene Targeted (GT) metagenomics - Strategies for enrichment, functional screens - Bioprospecting metagenomes for novel enzymes - Metatranscriptomics and metaproteomics

BIO-IMT-3453

Advanced Biochemical Engineering Bioreactions – Cell growth and product formation kinetics, growth associated, non-growth associated and mixed-growth associated product formation, cell growth and product formation models – quantitative review of biochemistry, metabolism and metabolic engineering, engineering aspects of microbial process and bioconversions – Bioreactors – Design of bioreactors – kinetic analysis, packed bed bioreactor, Fluidized bed batch, fed-batch and continuous culture – Bioprocess development – Exploitation of genetic engineering and bioprocess development, Plant cell culture, Mammalian cell culture, Enzyme technology – Downstream processing – Purification and separation technology, integrated bio separation schemes – Case studies – Production of protein pharmaceuticals as a paradigm of the application of biochemical engineering to advanced process development within the frame work of current business and regulatory requirements – Chemicals from biomass

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NBRI 100 level courses Course number BIO-NBRI-1001

Course content Biostatistics Summarization of Data: measures of center, dispersion, skewness Dependence of variables: Correlation, linear regression, logistic regression Basic probability distributions: Binomial, Normal, Chi-squares. Estimation of parameters: method of moments, maximum likelihood Testing of hypotheses: (a) parametric tests: t-test, z-test, chi-squares test, ANOVA (b) non-parametric tests: Mann-Whitney, Kruskal Wallis, Kolmogorov-Smirnov

BIO-NBRI-1002

Computation/bioinformatics Computers: Introduction, Evolution and Classification of computers. Fundamentals of computing. Bit and Byte, Introduction to types of Hardware and Software. Components of Computer. Introduction to operating systems. Introduction to Computer Viruses. Network: Introduction. Network structure and architecture, Hierarchical networks, Ethernet and TCP/IP family of protocols, transport protocol design. Types of network, Topologies of network, Router, Switch, Data Communication, Concept of Wireless networking, LAN, WAN, MAN, Security of the network, Fire-walls, Network Applications Information Technology: Concepts of client Server Architecture, Concept of search Engine, Database search engines. Introduction to Internet Introduction to Word, Powerpoint and Excel Introduction to Bioinformatics: History of Bioinformatics, Genome sequencing projects, Human Genome Project, Applications of Bioinformatics. Introduction to databases, Type and kind of databases, Applications and limitations. Literature Search Databases, Nucleic acid and protein databases, Animal and plant databases, Ensembl Genome project TIGR database, Biotechnological databases, Motifs and Pattern Databases, Databases for species identification and classification, Structural databases. Database Retrieval and deposition systems. Web tools and resources for sequence analysis: Pairwise and multiple sequence Alignment, Sequence similarity search: BLAST, Pattern recognition, motif and family prediction, Restriction map analysis, primer design, Gene prediction, Phylogenetic Tree, Protein structure prediction and visualization.

BIO-NBRI-1003

Basic Chemistry Thermodynamics Solutions and Ions Chemical bonding and molecular structure Chemical Kinetics Stereochemistry Introduction to drug discovery (Medicinal chemistry approach) Drug target, discovery and development (forward and reverse approach

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BIO-NBRI-1004

Research Methodology, Communication/ethics/safety Philosophy and structure of scientific thoughts, Objective and Motivation of Research, Meaning of the Research, What constitutes a research topic? How to select a research topic?, Importance of literature review, Selection of appropriate methodology, Collection of data, Interpretation of data, Writing research paper, Paper presentation in scientific conference, Statistical methods, Importance of documentation, Procedure for Hypothesis Testing, Values and Ethical Problems, Criteria of Good Research, Good laboratory practice, Chemical, Radioactive and Biological safety: Possible hazards and precautionary measures; do and don’ts upon exposure Research methodology, communication, ethics, safety Asking the right questions: Originality, Depth, Precision can co-exist Formulating and refining the hypothesis: Those who do not learn from the past are condemned to repeat it Study design: Recognizing and minimizing bias Experiment design: Sometimes less is more and the importance of controls Good lab practices: Record keeping, organizing data, organizing the lab space Data interpretation; objectivity, quantification, double blind studies and necessity of statistics Comunicating your data:writing up your research Comunicating your data: presenting your findings Radiation safety Chemical and Biosafety Intellectual property rights What is ethics, the different interpretations & historical instances of unethical science Case studies: Data fraud/ plagiarism and Human Ethics violation

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200 level courses Course number BIO-NBRI-2001

Course content Biotechniques and Instrumentation (compulsory) Part-I Chromatographic Analysis: GLC, HPLC, HPTLC and Flash chromatography Part- II- Spectroscopic analysis: UV, AAS and Mass spectrometry Part- III – Microscopy Light Microscopy, Confocal Microscopy, SEM and TEM NMR Spectroscopy in Plant Metabolomics: Introduction & Scope of NMR Spectroscopy and Applications of NMR Spectroscopy in Plant Metabolomics Electrophoresis: agarose and polyacrylamide gel (native and denaturing), 2-D gel Centrifugation (high speed, ultra and differential centrifugation) Common Molecular Biology Techniques Chromatography: affinity, ion exchange, hydrophobic chromatography, size exclusion and reverse phase chromatography Proteomics- MALDI-MS/MS, LC-ESI-MS/MS Practical Chromatography Techniques Spectroscopy Techniques

BIO-NBRI-2003

Biology of Inheritance What, why and how of this course Introduction, Scope of the course syllabus, Reading lists and handouts for students, Lottery for Term / Review paper topics In the beginning: Cell, chromosome, gene, hereditary units, hereditary materials, what is heredity? Unit of life – A cell and cellular basis for heredity: Why a cell divides? How it divides? Cell cycle, How does cell division impact heredity? Cell division – rules and parameters Chromosomal basis for heredity: Chromosome structures, its functions, chromosomes in cell division, chromosomes in heredity, Aneuploids, Polyploids Everyone had an opinion about heredity: Assorted theories for inheritance, Darwinism, Neo-Darwinism, Lamarckism Gregor Johann Mendel and his seminal contributions to our understanding of genetics and heredity: Where would we be if Mendel had not made his landmark contributions? Mendelism: Genes, determinants, alleles, Mendel’s postulates, Laws of inheritance, their applications in real life, Universality or otherwise of these laws What happens when Mendelian laws are not followed / obeyed? Epigenetics, Transposition, Pleiotropy, Heterosis What happens when heredity rules go wrong? Inherited disorders, chromosome errors, single gene mutations, induced mutations Mechanisms of inheritance: Recombination, crossing over, chimerism, gene dosage, dominance and incomplete dominance, linkage and linkage disequilibrium, QTLs Does heredity in individuals differ from or impact on populations and communities? Population genetics, genetic communities, quantitative genetics Molecular genetics: Architecture of a Mendelian locus, its dissection and mapping, linkage, genetic and molecular mapping Why is study of genetics central to: Our understanding of evolution, populations, communities, ecology, recombinant DNA technologies? Students display their learning: Return of term / review papers, Seminars / Round-Table brainstorming How far did we succeed? Evaluation times are here again!!! Students to complete a test (30 min, MCQ with negative markings; 1/3 descriptive question); Students evaluate Faculty (15 min – Predesigned questionnaire);

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Valedictory and Closure of the Course (15 min) BIO-NBRI-2005

Genomics: Information flow in Biological Systems Introduction: From Sequence to function in the Age of genomics, Genome databases of various plants. Genome Organization: Nuclear, Mitochondrial and Chloroplast Genome Genome analysis: Cloning systems used in genomics, Sequencing and analyzing genome, Principles of Gene Annotation and prediction, tools and resources Genomes and transcriptomes of model organisms Small RNAs and their role in regulation of gene expression Functional genomics: Strategies to find important genes in the genome and their functional analysis Differential gene expression profiling methods (differential display, subtractive analysis, Microarrays, comparative transcriptomics) Comparative genomics and synteny (Multiple Sequence Alignments & Phylogenetic analysis) Practical Courses: Demonstration of microarray system Demonstration of 454 whole genome sequencing system Demonstration of Sequnome system

BIO-NBRI-2009

Plant-Microbe Interaction Plant associated soil micro-organisms and microbial diversity Plant responses to PGPRs and pathogens Rhizosphere dynamics, effectors and signaling Plant microbe interaction in stressed conditions Molecular mechanisms of PGPRs and pathogens Application of Proteomics in plant microbe interaction Role of mutagenesis in plant microbe interaction Bioinoculants for nutrient and disease management Virus structure and morphology, plant virus diseases and symptomatology Transmission of plant viruses Replication and translocation of viral genomes Genome organization of viruses Practical Techniques for study of PGPRs and pathogens-I Techniques for study of PGPRs and pathogens-II Methodology for assay, detection and diagnosis Modern approaches of virus control

BIO-NBRI-2010

Plant Environment Interaction Environment and Sustainable Development. Environment Pollution in National and Global Perspectives Sources of Air Pollutants and Plant Responses Sources and Fate of Pollutants in the Aquatic Ecosystems Responses of Plants to Water Pollution Sources and Behavior of Soil Pollutants Responses of Plants to Soil Pollutants Prevention and Mitigation of Air Pollution Prevention and Control of Water pollution Energy Resources and Conservation Plant adaptation to Environmental stress Environmental Degradation and Restoration Biomonitoring of Environmental contaminants Environmental Impact Assessment & Auditing Practical

Final Draft

To study improvement in physico-chemical characteristics of waste water after treatment with aquatic plants, Physiological and Biochemical response of plants to toxic metals BIO-NBRI-2012

Cell Signaling Cell communication: Inter-organellar communication Nucleus-plastidmitochondrion, Plasmodesmata, signal delivery systems. Membrane receptors, Protein kinases: Ion channels, G-protein-coupled receptors, Wall associated kinases, MAPK kinases, Ca++-calmodulin system. Ethylene signalling: Plant two-component signaling systems Ethylene biosynthesis, ethylene signaling cascade ethylene responses in different tissues. Auxin signalling: Auxin receptors, Auxin-responsive gene expression, Proteolysis and auxin signalling. ABA signalling: Biosynthesis and Catabolism Pathways, Regulation of ABA synthesis and metabolism, ABA Signaling in seed maturation processes Proteolysis and protein interactions, ABA Signaling in Guard Cells, ABA as Antagonizing Signal to Light in Stomatal Movement. Cytokinins, Gibberellins: Cytokinin metabolism, Cytokinin signal transduction, Gibberellin metabolic pathway, Genes of GA Biosynthesis and regulation, Signal transduction pathway, Downstream transcriptional events induced by Gas, Sites of GA Signaling. Brassinosteroids, strigolactones, Signaling by JA, SA, polyamines: Biosynthesis, metabolism, signal transduction-mode of action Light signalling: Phytochrome-mediated responses-energy dependence, Structure of phytochromes, Phytochromes- mechanism of action, Phytochrome interacting factors, Phytochrome-regulated gene transcription Cross talk between signaling pathways

BIO-NBRI-2016

Developmental Biology-Plants Root - Architecture and types, cell types, molecular basis of root development, lateral root formation, adventitious roots, root hairs, storage roots, gravitropism, hormonal control, root symbiosis, root apex Shoot - Shoot apical meristem, cell division,differentiation, xylogenesis, phloem, branching, secondary wood, molecular basis of development, hormonal control, cell growth, programmed cell death Leaf - Types, phyllotaxis, size and shape control, cell types, venation, plastid biogenesis, stomatal development, senescence Flower - Types, determinacy, ABC model, architecture, pigmentation, control of flowering time, photoperiod control, senescence, hormonal basis, scent, development of reproductive organs, pollination, apomixis Reproduction – Male and female gametophyte development, Pollination, fertilization, zygote, embryogenesis, Molecular basis, male sterility self incompatibility, somatic embryogenesis Fruit - Development, size control, ripening, parthenocarpy, molecular basis, hormonal control, climacteric fruits, abscission, sex determination Seed - Genetic control of seed development, seed structure, types of storage reserves, molecular basis, oil seeds, dormancy and germination, hormonal control, recalcitrance in seeds, photomorphogenesis, endosperm Secondary growth, cambium, trichomes, fibre, totipotency

BIO-NBRI-2017

Epigenetics and Chromatin Organization Theory Epigenetics: DNA methylation and concept of epigenetics, Histone modifying enzymes and their role, Chromatin modifying matchinary, Chromatin architecture, Histone modifications, Hostone methylation, demethylation etc Transcriptional Gene Regulation: Operon Concept,, Transcription Factors and Classification, Promoters, cis-regulatory elements and enhancers, Pre-initiation complex and RNA Polymerase, transciprtion elongation and termination Gene Silencing: Transcriptional gene silencing, Post transcriptional gene silencing : Small RNA world and mechanism of regulation Post-transcriptional gene regulation: RNA processing, Inron splicing etc., Post-

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translational modifications of protein and their regulation Practical Nuclear Protein preparation, EMSA, Chromatin Immunoprecipitation and analysis BIO-NBRI-2018

Homeostasis and feedback in biological systems Light use and leaf gas exchange: Leaf anatomy, light interception and gas exchange, Chloroplasts and energy capture Carbon dioxide assimilation and respiration: Modes of photosynthesis, Photorespiration, Respiration and energy generation Gaining water and nutrients: root function: Root system architecture, Extracting water and nutrients from soil, Soil–root interface, Absorption of water and nutrients by roots Using water and nutrients: cell growth: Membrane transport and ion balance, Regulation of nutrient ion and Cell enlargement Vascular integration and resource storage: Long-distance transport of water and nutrients and Distribution of photoassimilates within plants, Phloem transport, Phloem loading, Phloem unloading and sink utilization Growth analysis: a quantitative approach: Concepts and techniques, Environmental physiology and Crop growth analysis

BIO-NBRI-2021

Molecular breeding of plants Breeding strategies of self and cross pollinated crops Mode of reproduction in plants, pure line and mass selection, pedigree and bulk population, backcross, population improvement, Self incompatibility and male sterility and their use in hybrid seed production, recurrent selection Experimental designs in relation to plant breeding Randomized complete block design (RBD); latin square designs; augmented block design, Merits and limitations of different designs, Statistical and biometrical methods in plant breeding Analysis of Variance (ANOVA), Correlation, regression and path analysis, heritability, genetic advance, genetic gain, combining ability, heterosis and inbreeding depression, Tests of significance: Sampling distribution of mean and standard error; z and t-test, Chi- square test for goodness of fit, F test. Mutation and polyploidy breeding Selection of parents, mutagen treatment and handling of treated material, development of polyploids and their evaluation, Molecular Markers Overview of markers, Concept, Development methodology of AFLP, SSR, and SNP markers, Merits and demerits of different types of markers Mapping populations and phenotyping Types and developmental strategies (F2, RILs, DH lines), Merits and demerits of various types of mapping populations, Field experimental design and phenotyping Construction of linkage map Linkage map, marker polymorphism, genotyping, Data scoring, softwares and Linkage analysis, Germplasm characterization and Diversity Analysis Selection of markers, Genotyping, Data acquisition, Softwares, statistical methodologies and analysis Quantitative Trait Loci (QTLs) and QTL analysis Principle of QTL analysis,Genotyping, phenotyping, Methods to detect QTLs (Single markers, Simple and composite interval mapping), data acquisition, Softwares and analysis, Association mapping in plants Introduction, Choice of population, Analysis of population structure, Trait evaluation (phenotyping), Identification of marker/sequence polymorphism, Statistics of association mapping-Linkage disequlibrium (LD), measure of LD, factors affecting LD Marker Assisted Selection (MAS) Gene tagging by Bulk segreegent Analysis (BSA) and near isogenic lines (NILs), Gene pyramiding, advanced backcross QTL (AB-QTL) analysis, Breeding by

Final Draft

Design, Effectiveness and efficiency of MAS over phenotypic selection, foreground and background selections; marker assisted hybrid (MAH) breeding; important examples of successful MAS. Practical Emasculation, pollination, Genotyping (PAGE and ABI DNA Analyzer), data scoring, polymorphism detection.

BIO-NBRI-2025

Biodiversity Aims, objectives and dynamics of Plant biodiversity Bio-geographic regions of plant biodiversity in India and world Diversity within different plant groups Assessment of biodiversity through classical taxonomic methods Ecological methods for plant diversity inventorying Drivers of biodiversity loss Role of Biosphere Reserve, National Parks, Wild Life Sanctuaries, Sacred Grooves in biodiversity conservation Species distribution and endemism Biodiversity and its sustainable uses Biodiversity and traditional knowledge Development of plant databases and its management Biodiversity legal and policy instruments Biodiversity, ecosystem function and ecosystem processes Ecological niche Impact of climate change on plant biodiversity Practical work: Field visit and ecological methods to study biodiversity

BIO-NBRI-2486

Plant morphogenesis and regeneration History and scope of plant tissue culture, concept of cellular differentiation Dedifferentiation, re-differentiation, totipotency and media composition. Plant Growth Regulators Auxin, cytokinin, GA, ABA, JA, ethylene signaling pathway Organogenesis and somatic embryogenesis: Fundamental aspects of morphogenesis, somatic embryogenesis and androgenesis, mechanisms, techniques and utility. Culture of different plant parts: Root, stem, leaf, meristem culture, ovary, ovule and nucellus culture, embryo culture, endosperm culture. Production of Haploids: Techniques for development of androgenic haploids, factors affecting anther culture, pollen culture, gynogenesis, applications of haploids. Somatic Hybridization: Protoplast isolation, fusion and culture, hybrid selection and regeneration, possibilities, achievements and limitations of protoplast research Application of Plant Tissue Culture: Clonal propagation, artificial seed production/ encapsulation somaclonal variation, production of secondary metabolites/natural products, automation in plant tissue culture, cryopreservation and germplasm storage Specific gene transfer: Direct and indirect methods, current status and limitations. Practical Laboratory organization and equipments, preparation and sterilization of media. Explant preparation, surface-sterilization, inoculation and subculture. Hardening and field transfer of tissue-raised plants, excised root culture, callus culture, encapsulation of seeds/somatic embryos.

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300 level courses Course number

Course content

BIO-NBRI 3001

Seminar Course (compulsory)

BIO-NBRI 3003

Cell and tissue engineering Genetic engineering of plant cells -Transgenic plants Methods of direct and Agrobacterium mediated gene transfer (Ti plasmid). Methods for DNA transformation: electroporation, microinjection, particle-gun technology. Strategies for crop improvement with special mention of biotic and abiotic resistant plants and value addition. Recombinase-directed chromosome engineering in plants Cre & lox system FLP& FRT system PhiC31 & aatP-attB system R and RS system/ParA& MRS system Production of pharmaceutically important drugs and therapeutics using genetic engineering Large scale production of secondary metabolites using cell and suspension cultures. Hairy root culture and Ri plasmid, Hairy root cultures as phytochemical factories and process of elicitation. Recombinant therapeutic protein production (medical molecular pharming) in plant cells/tissues. Metabolic Engineering of major metabolic pathways and products. Cloning and characterization of secondary metabolic genes. Bioengineering and other means to develop new plant products. Use of genetic engineering and molecular biology tools for Metabolic Engineering. Plant Cell reactors- type of reactors, comparison of reactor performances, Immobilized plant cell reactors. Practical Experiments Electroporation & particle-gun technology Molecular characterization of transgenic plants Hairy root induction and establishment Demonstration of bioreactor

BIO-NBRI-3486

Climate change and Plants Sources of Green House Gases (GHGs) and their impact, Mitigation strategies of GHGs, Impact of elevated CO2 and temperature on plants, Plant responses to O3 stress, Drought tolerance mechanism of plants, Crop simulation modeling, Carbon sequestration, Green technologies to combat climate change, Climate change and forest ecosystems, Climate change and plant diseases, Climate simulation modeling, Remote Sensing & GIS, FACE technology Practical Ozone monitoring techniques Methane efflux measurement Ambient Air Quality Monitoring

BIO-NBRI-3487

Bioremediation Bioremediation: Principles and Applications Bacterial Remediation of Metal and Metalloid Contamination Fungal Bioremediation Mycorrhiza and Rhizoremediation Phycoremediation

Final Draft

Biodegradation of Recalcitrant Organic Wastes Phytoremediation of Contaminated Water & Constructed Wetlands Phytoremediation of Contaminated Soils Phytoremediation and Role of Nutrient Management Role of Nanotechnology in Bioremediation Scope of Soil Carbon Sequestration in Degraded Soils Limiting Factors in Bioremediation Processes Practical Protocols/ Techniques of Soil Bioremediation using Microbes Protocols/ Techniques of Soil Phytoremediation Protocols/ Techniques of Phytoremediation for Aquatic Ecosystems Use of Soil Enzymology in Monitoring of Bioremediation BIO-NBRI-3488

Environmental Biochem and Biotech Advances in Environmental Biotechnology Physiology of toxic metal transport and accumulation by plants I Physiology of toxic metal transport and accumulation by plants II Biochemical basis of metal hyperaccumulation in plants Detoxification mechanisms of toxic organic compounds Transgenic microbes for pollution management Molecules and pathways associated with metal detoxification in plants. Gene mining for metal accumulation and transport Transgenic plants as hyperaccumulators of heavy metals. Transgenic crops for low accumulation of toxic metals. Metagenomics of polluted habitats. GM crops and their impact on Environment. Practical Element estimation by AAS, ICPMS Enzyme assays- Antioxidant enzymes. Measurement of non protein thiols/Phytochelatins Gene expression by heavy metals (Microarray/RTPCR).

BIO-NBRI-3489

Taxonomy and speciation Unit-I: Taxonomy of plants History of plant taxonomy and classification of angiosperms International Code of Botanical Nomenclature Modern trends in Taxonomy: (a) Numerical taxonomy, chemo-taxonomy, cytotaxonomy, and (b) Palynology, embryology, anatomy and palaeo-botany Relevance of Herbaria & Botanical Gardens Systematics of Pteridophytes and Gymnosperms (General characters, classification, important families) Systematics of non-vascular plants Plant descriptors, systematic of some selected families in Dicots & Monocots Methods and techniques in plant taxonomy and herbarium Unit –II: Molecular Systematics and speciation Species concept Speciation in plants Molecular Systematics: Concepts and applications Molecular markers in plant systematics Procedures for collecting and sampling of plant materials Molecular Phylogenetics Phylogenetic Inferences Phylogeography: concepts and case studies in plants

BIO-NBRI-3490

Plant Conservation and Reproductive Biology Conservation biology: principles and applications

Final Draft

BIO-NBRI-3491 BIO-NBRI-3492

Final Draft

Introduction to the science of conservation biology, Threats to plant diversityCauses and consequences of Habitat fragmentation, destruction, overexploitation, diseases, invasive aliens, pollution, and climate change Vulnerability to extinction Habitats, Species and Populations vulnerable to extinction, Examples and Case Studies Conservation at species and population levels: Population genetics and conservation I Measurement of genetic diversity, Population bottlenecks and maintenance of genetic diversity Population genetics and conservation II Gene flow, Reproductive/mating systems; -inbreeding and out -breeding depression Effective population size and management of genetic diversity Conservation biology of rare and endangered plants Concepts and practical approaches, Case studies, Designing framework for new case studies Conservation at Landscape and Ecosystems levels Methods and strategic approaches, Case studies Plant species loss: assessment of extinction risks IUCN Red lists: Criteria and Classification, National Red Lists, Biodiversity Hot spots Plant conservation methods and strategies In situ conservation, Ex situ conservation, Integrated conservation, Recovery, Reintroduction and Rehabilitation of endangered habitats and species, Case studies; visit to botanic garden, conservatories, gene banks, etc. Introduction to Plant Reproductive Biology Modes and mechanics of reproduction in plants Functional Mechanism of Sex gametes and Reproductive behaviour Ontogeny and development of sex gametes in cryptogams, Ontogeny and development of sex gametes in phaenerogams, Floral biology and phenology Reproductive Progression and Plant Breeding Intra and Inter gametophytic mating and sporophyte development , Nature of breeding system, homozygosity and heterozygosity, Reproductive success and origin of polyploid genotype Pollen and Pollination Biology Structural and developmental pattern of pollen, factors influencing pollen productivity (environment, genetic) and pollen syndrome, Pollination mechanism, plant-pollinator interactions , Pollen and pistil interaction Fertilization and Seed Biology Fertilization mechanism, embryo and endosperm development, Fruit biology, seed formation, dispersion and syndrome, Seed germination and seedling demography Abnormal Reproductive Behaviour in Plants Male sterility and self incompatibility, Polyembryony, parthenogenesis, parthenocarpy, Apogamy, apomixis, apospory Recent Trends in Reproductive Biology In vitro culture of pollen, spores, gametophytes, sporophytes, embryo and tissues, Physiological and molecular aspects of sex gamete expression, differentiation, development and floral induction , Production of androgenic plants and somatic hybridization Reproductive Biology and Threatened Plants Genetic load and reproductive barriers, Physiological and genetic infringement of reproductive barriers, Case study, visit to conservatory, fernery and moss houses etc . Economic Plants and Pharmacology

Floriculture and Agronomy

NCL 100 level courses Course number

Course content

Course number

Course content

BIO-NCL-1001

Biostatistics Summarization of Data: measures of center, dispersion, skewness Dependence of variables: Correlation, linear regression, logistic regression Basic probability distributions: Binomial, Normal, Chi-squares. Estimation of parameters: method of moments, maximum likelihood Testing of hypotheses: (5 lectures) (a) parametric tests: t-test, z-test, chi-squares test, ANOVA (b) non-parametric tests: Mann-Whitney, Kruskal Wallis, Kolmogorov-Smirnov

BIO-1-002

Computation/bioinformatics Computers: Introduction, Evolution and Classification of computers. Fundamentals of computing. Bit and Byte, Introduction to types of Hardware and Software. Components of Computer. Introduction to operating systems. Introduction to Computer Viruses. Network: Introduction. Network structure and architecture, Hierarchical networks, Ethernet and TCP/IP family of protocols, transport protocol design. Types of network, Topologies of network, Router, Switch, Data Communication, Concept of Wireless networking, LAN, WAN, MAN, Security of the network, Fire-walls, Network Applications Information Technology: Concepts of client Server Architecture, Concept of search Engine, Database search engines. Introduction to Internet Introduction to Word, Powerpoint and Excel Introduction to Bioinformatics: History of Bioinformatics, Genome sequencing projects, Human Genome Project, Applications of Bioinformatics. Introduction to databases, Type and kind of databases, Applications and limitations. Literature Search Databases, Nucleic acid and protein databases, Animal and plant databases, Ensembl Genome project TIGR database, Biotechnological databases, Motifs and Pattern Databases, Databases for species identification and classification, Structural databases. Database Retrieval and deposition systems. Web tools and resources for sequence analysis: Pairwise and multiple sequence Alignment, Sequence similarity search: BLAST, Pattern recognition, motif and family prediction, Restriction map analysis, primer design, Gene prediction, Phylogenetic Tree, Protein structure prediction and visualization.

BIO-1-003

Basic Chemistry Thermodynamics Solutions and Ions Chemical bonding and molecular structure Chemical Kinetics Stereochemistry Introduction to drug discovery (Medicinal chemistry approach)

Final Draft

Drug target, discovery and development (forward and reverse approach BIO-1-004

Research Methodology, Communication/ethics/safety Philosophy and structure of scientific thoughts, Objective and Motivation of Research, Meaning of the Research, What constitutes a research topic? How to select a research topic?, Importance of literature review, Selection of appropriate methodology, Collection of data, Interpretation of data, Writing research paper, Paper presentation in scientific conference, Statistical methods, Importance of documentation, Procedure for Hypothesis Testing, Values and Ethical Problems, Criteria of Good Research, Good laboratory practice, Chemical, Radioactive and Biological safety: Possible hazards and precautionary measures; do and don’ts upon exposure Research methodology, communication, ethics, safety Asking the right questions: Originality, Depth, Precision can co-exist Formulating and refining the hypothesis: Those who do not learn from the past are condemned to repeat it Study design: Recognizing and minimizing bias Experiment design: Sometimes less is more and the importance of controls Good lab practices: Record keeping, organizing data, organizing the lab space Data interpretation; objectivity, quantification, double blind studies and necessity of statistics Comunicating your data:writing up your research Comunicating your data: presenting your findings Radiation safety Chemical and Biosafety Intellectual property rights What is ethics, the different interpretations & historical instances of unethical science Case studies: Data fraud/ plagiarism and Human Ethics violation

BIO-NCL-1521

Research Methodology

BIO-NCL-1522

Analytical Tools and Instrumentation

BIO-NCL-1523

Basic mathematics and numerical methods

Final Draft

Good laboratory practices, Safety in the laboratory, First Aid in the laboratory, Maintenance of laboratory records, Scientific literature management, Communication skills (scientific writing and presentation), Intellectual property management & planning, Ethics in Science, Computer applications and tools, Statistical methods & Data analysis

Thermal methods (TG, DTG, DTA, TMA, DSC), X-ray methods (XRD, XRF, SAXS), NMR (1H, 13C) and other Spectroscopic methods (EPR, IR, UV, Fluorescence), Chromatographic methods (TLC, GC, LC), Mass spectroscopy, Electron Microscopy (SEM, TEM), Electron Probe Micro Analysis (EDS, WDS), Quantitative Analysis (AAS, ICP, CHN)

Determinants and Matrices, Complex Variables, Vector analysis, Infinite Series, Special Functions, Differential Equations, Interpolation and Approximation, Numerical differentiation and Integration, Basic Linux, Introduction to Algorithms, basic programming, Shell and Shell Scripting, Network Computing and Parallel Computing, Matlab/Scilab/Octave/Gnuplot

BIO-NCL-1524

BIO-NCL-1525

Basic Chemistry for Interdisciplinary sciences Basics of inorganic, organic, physical and biochemistry, Nomenclature (IUPAC), molarity, molality and normality, types of bonding, Ionic, covalent and nonbonding interactions, Acids and bases, Atomic structure, periodic table and periodic properties, stoichiometry, chemical reactions and kinetics, solvent effects, functional groups in organic compounds, general named reactions and reaction mechanisms, carbohydrates, lipids, proteins, nucleotides, enzymes, photosynthesis

Introduction to Nanoscience and Nanotechnology General considerations, Introduction, definitions, consequences of size reduction, Properties: structural, thermodynamic, optical, electrical and magnetic properties, Methods of synthesis, Surface modifications, factors governing the stability and assembly, Characterization of nanomaterials, Applications of Nanomaterials

BIO-NCL-1526

Introduction to Chemical Biology Amino Acids, Peptides & Proteins, The Chemistry of Carbohydrates, Nucleic acids, The Chemistry of Enzymes, Lipids, Fats & Steroids, Drug discovery, Drugs from Nature, Drug interaction

BIO-NCL-1527

Final Draft

Basic techniques in biology Basic techniques in microbiology Basic techniques in plant tissue culture Basic techniques in plant molecular biology Basic techniques in animal cell culture Basic Entomological techniques Microscopy - Light and florescence Freeze drying, centrifugation, ultra-centrifugation, ultra-filtration, etc. Electrophoretic techniques (DNA/RNA/Protein-Native/denaturing) / IEF and Agarose / PAGE / Capillary electrophoresis Chromatography techniques (Ion exchange, Affinity, Gel filtration) Purification and characterization of biomolecules (Proteins & metabolites)

200 level courses Course number BIO-NCL-2521

Course content

Advanced Techniques in Biology Sequencing of nucleic acids and proteins Functional characterization of biomolecules Advanced microscopy (TEM, SEM, Confocal, AFM, etc.) Biophysical techniques (UV, Fluorescence, CD) Spectrometry (GC-MS, LCMS) High performance chromatography (HPLC, FPLC) Tracer techniques NMR for biomolecules Proteomics (2D, MALDI-TOF, ESI, Database search, de novo sequencing) Microarray analysis Techniques in molecular biology (PCR, RT-PCR, Sequencing, Southern, Northern, etc.) Gene cloning and over-expression: identification of genes, designing primers, selecting vectors and cloning, expression in cells, solubilization of inclusion body, protein purification, site-directed mutagenesis Immunological techniques- Antigen-Antibody reaction, ELISA, RIA, In situ hybridization, immunoblotting, Western blotting, etc. Techniques in structural biology: crystallization and X-ray structure determination Bioinformatics tools and databases

BIO-NCL-2522

Introduction to infectious diseases Human microbiome and normal flora Pathogens responsible for human infectious diseases i. Virus: classification, biology and diseases caused / Specific case studies will be discussed ii. Bacteria: classification, biology and diseases caused / Specific case studies will be discussed iii. Protozoans: classification, biology and diseases caused / Specific case studies will be discussed iv. Fungal: classification, biology and diseases caused / Specific case studies will be discussed v. Worm: classification, biology and diseases caused / Specific case studies will be discussed Virulence mechanisms Host pathogen interaction and overview of host immune response against specific pathogens Overview on veterinary pathogens Epidemiology / Transmission / preventive strategies Diagnostic methods and techniques against infectious diseases Drugs / Drug resistance / Drug discovery Vaccines Infectious disease studies in the ‘post genomic era’. Overview of genome sequencing efforts, and highlight the importance of genome information in helping to under the biology and disease caused by specific pathogens. Discuss the role of genomics in epidemiology, diagnosis and drug discovery Special focus on neglected tropical diseases.

BIO-NCL-2523

Mathematics and statistics for biologists Introduction to algebra and geometry Trigonometry: Ratios of single and compound angles, their relations, inverse function. Complex numbers: algebra and geometrical interpretation

Final Draft

Matrices and determinants: algebra, inverse of matrix, elementary transformations and solving equations Vectors: algebra, coordinate system, unit vectors, direction cosines, vector operations, products. Eigen value and eigen vectors Coordinate transformations and rotation about a general direction Calculus: continuity and limit of functions, derivatives, integrals, differential equations, Fourier transform, applications. Biostatistics: introduction Probability distributions (normal, binomial and Poisson), Sampling techniques, Correlation and Regression, Null hypothesis, Confidence intervals, Significance levels Experimental Design and Methods of sampling, Basic and Two-Way ANOVA

BIO-NCL-2524

Structure determination and analysis of biomolecules Introduction to the structure of biomolecules: DNA, RNA, sugar, lipid, protein Conformation of biopolymers, energetics of folding Crystallization of Proteins: Principles and techniques, preparation of heavy atom derivatives, Freezing protein crystals for storage and data collection. Single crystals: Three-dimensional structure determination using protein crystallography, Arrangement of molecules in crystals, Lattice, symmetry, unit cell, point groups, space groups. Diffraction: X-ray diffraction, Laue an Bragg equations, reciprocal lattice, structure factor equation, Fourier transform, phase problem, diffraction data collection, indexing, systematic absences Structure determination: Solution to phase problem using direct methods, molecular replacement, Patterson method, isomorphous replacement and anomalous scattering, phasing of protein reflections, accuracy of phasing and refinement of phases, electron density and model fitting, Refinement: methods for structure refinement, structure validation, structure deposition, database. Fiber diffraction and small angle scattering Biophysical and spectroscopic techniques: NMR, Fluorescence, Circular Dichroism.

BIO-NCL-2525

Concepts in Microbiology Topics Architecture of Bacterial cell Architecture of Fungal cell Taxonomy of bacteria Taxonomy of fungi Bacterial genetics Fungal genetics Microbial diversity Fungi from different environments Strain improvement Whole cell & enzyme immobilization Secondary metabolites Morphological and physiological characterization of microorganisms

BIO-NCL-2526

Concepts in Plant Biotechnology Structural genomics including genome architecture, gene structure, large insert libraries and classical genome sequencing, next generation sequencing, physical mapping Functional genomics including differential expression (microarray technology, real time and digital PCR), over expression, gene silencing (miRNA and siRNA), mutation, transposable elements, Genome-wide technologies (Transcriptomics,

Final Draft

TILLING, SAGE, etc.) Molecular markers including concept, properties, classes, advantages and applications, population development Plant cell, tissue and organ culture Plant transformation methods including tissue culture and non tissue culture based, Agro bacterium mediated co-cultivation, particle bombardment, plant vectors, promoters and analysis Endophytes and their applications Phytoremediation BIO-NCL-2527

Advances in Nanoscience and Nanotechnology Low-dimensional structures: Quantum wells, Quantum wires, and Quantum dots, Nano clusters & Nano crystals, fullerenes, carbon nano tubes and graphene, Nano Composites, synthesis and characterization techniques, Properties at Nano Scales and comparison with bulk materials, fabrication techniques, general applications, nanomaterials in biology.

BIO-NCL-2528

Advances in Chemical Biology Amino Acids, Peptides & Proteins: Structure and functions of peptides and proteins, Design of poly peptides, Peptide hormones and their pharmaceutical significance, Peptide mimetics as therapeutics The Chemistry of Carbohydrates: Glycosylation methods, Oligosaccharide synthesis and biosynthesis, Sugar derivatives and reactions, Glycoconjugates and glycomimetics Nucleic acids: Structural aspects of nucleic acids, Building blocks of nucleic acids , Structure & function of DNA and RNA, Nucleic acid mimetics & their therapeutic applications. The Chemistry of Enzymes: Enzymes: Classification & Nomenclature, The Mechanism of Enzyme action, Enzymes as Catalysts Lipids, Fats & Steroids: Chemical synthesis & biosynthesis, Drug discovery , Basic principles of medicinal chemistry, The process of drug discovery and combinatorial chemistry, Case studies in drug discovery, Drugs from Nature: Introduction to natural products chemistry, Natural products based drug discovery, Naturally occurring antimalarials, anticancer and antimicrobial agents.

BIO-NCL-2529

Advanced Biomaterials Definition of biomaterials, Surface property requirements of biomaterials, Types of materials used in medicine, Synthesis and surface characterization, Biology of wound healing, foreign body response and tissue remodeling, Molecular and cellular interactions of materials with biological environment, Degradation and long term fate of materials used in medicine, Requirements of biomaterials for biomedical implants, surface coatings, wound dressings, sutures, cardiovascular devices, ophthalmology, dentistry, orthopedics and cosmetic surgeries, Applications in drug delivery and tissue engineering, Standard protocols for testing the efficacy and efficiency of biomaterials, The regulatory environment for biomaterials, Some concepts for design development of common biomaterials.

Final Draft

300 level courses Course number BIO-NCL-3521

Course content

Molecular recognition and molecular interactions in structural biology Databases and tools used in structural biology Enzyme kinetics, active site and inhibition Metabolism of DNA and RNA: Replication, recombination, transcription Ribosome structure and mechanism of protein synthesis. Protein folding, degradation and prediction of protein conformation Protein-DNA interaction: case study of transcription factors and student assignment. Protein-carbohydrate interactions: case study of lectins and student assignment. Structural studies of genetic diseases and student assignment. Proteins as enzymes: case study of proteases and student assignment. Proteins as enzymes: carbohydrate digesting enzymes and assignment. Protein superfamily: Ntn hydrolases and assignment. Molecular recognition: case study of antigen-antibody interactions and student assignment. Virus structures. Membrane proteins and student assignment Protein evolution: globins and cytochromes and student assignment Cell signaling and cell-cell interactions and student assignment Cell motility and transport and student assignment Structure based drug design: case study. Structural genomics, proteomics and metabolomics

BIO-NCL-3522

Advances in Microbiology and Microbial Technology Fungal morphogenesis Microbial diversity: Metagenomics/Functional genomics Evolution of bacteria Evolution of fungi Host-pathogen interaction Microbial and plant lectins Signal transduction Programmed cell death Metabolic Engineering Synthetic biology Agriculture microbiology: Biofertilizer and Biocontrol agents Industrial enzymes Biotransformation Concept to commercialization Submerged and solid state fermentation Down stream processing Nanobiotechnology Single cell microbiology IPR Surface expression of enzymes

BIO-NCL-3523

Applications in Plant Biotechnology Plant –pathogen/microbe/insect interactions, plant defense, defense proteins, such as AI, PI, lectins, defensins, etc. Abiotic stress tolerance in plants Plant genetic engineering for crop improvement with case studies, safety practices in handling GMOs

Final Draft

Applications of molecular markers in linkage mapping, gene tagging, gene introgression, synteny mapping, Hybrid testing, germplasm analysis, DNA fingerprinting, MAS, map based cloning Identifying and mapping of QTLs including strategies of QTL mapping (SMA, SIM, CIM, MTIM), QTL x QTL and QTL x environment interactions, expression QTLs, Softwares used, Association mapping Biodiversity including genetic diversity, molecular diversity and taxonomy, DNA barcoding, population genetics, conservation of diversity and endangered species Metabolomics including plant secondary metabolites, functional molecules, metabolic engineering, analytical methods Molecular farming and Biotransformation Proteomics including recognition, sequencing, applications of proteomics in plant biotechnology, identification, differential analysis, intensity fading etc. Application of nano-biotechnology in plant sciences

BIO-NCL-3524

Beyond Genomes: Concepts in comparative and functional genomics Overview of genome sequencing, assembly and annotation. Will discuss recent advances in genome sequencing technology and assembling short reads, gene finding and annotation. Accessing genome sequences and genomic-scale datasets: Genome browsers and databases Genome wide experiments 1. Gene expression and genetic variation analysis by microarray and sequencing. 2. Gene silencing / knock down techniques (micro RNA / siRNA) 3. Epigenetics / Histone modifications 4. Chemical genomics Comparative genomics 1. Synteny mapping 2. Overview of phylogenetics, orthology (orthologs / paralogs), gene duplication and functional specialization. Case study – the human kinome 3. Lateral gene transfer and functional specialization. Case study – the apicoplast organelle genome and function of apicomplexan parasite Metagenomics Population genetics Genome wide association studies (GWAS) and systems biology – integrating diverse datasets to understand biological functions and disease mechanisms Genomics and Drug discovery. The druggable genome concept. The EnCODE and 1000 genome projects Case study on current status of select genomes (humans / mouse / Arabidopsis / Plasmodium species / Mycobacterium species)

BIO-NCL-3525

Chemistry and biology of Heterocycles Privileged heterocycles, Electronic properties, reactivity (electrophilicity and nucleophilicity), Synthetic methodologies, Biological properties of Natural products and drug candidates, Biosynthesis, Dimeric compounds and related stereochemistry

Final Draft

CSIR-North-East Institute of Science & Technology (NEIST), Jorhat AcSIR Course on BIOLOGICAL SCIENCE General All candidates in AcSIR Biological Sciences Ph. D. programme should earn an aggregate of 20 credits (12 credits through course work, 4 credits for project proposal writing and 4 credits for CSIR-800). The different levels of courses offered are: 100 Level: Minimum 2 courses of total 4 credits 200 Level: Minimum 2 courses of total 4 credits 300 Level: Minimum 2 courses of total 4 credits

Part A – Compulsory Courses

COURSE DESCRIPTION 100 Level Courses A minimum of two courses of 4 credits in total. These courses will be on “Research Methodology and Communication” and “Biodiversity and Environmental studies”.

These

courses will be abbreviated as AcSIR-BS-101 and AcSIR- BS-102. These two courses are compulsory for all Biological Science Ph. D. candidates.

Final Draft

Part I (Compulsory Paper) Basic and Fundamental Techniques Per week L-T-P-C = 4-0-0-0.4 (Total L-T-P-C = 40-0-0-4) 2.5 months

100 level courses Course number

Course content

Bio-NEIST-1-001

Research Methodology Introduction to research concept, identification, selection and formulation of research problem, justification, hypothesis, literature retrieval, survey, bibliography presentation, digital resource (internal), data collection, sampling techniques, collection, documentation, presentation and interpretation of data

Bio-NEIST-1-002

Research communication Communication skill, presentation of scientific finding & discussion, scientific manuscript writing, literature survey, online search toolsBiomed Central, Pub med, Scopus, Scifinder, Web of Science etc.

Bio-NEIST-1-003

Bio-statistics Basic concept of bio-statistics and its application, probability, Correlation, regression, F-distribution, Analysis of variance (ANOVA), Standard deviation, Use of computer software for data analysis etc.

Bio-NEIST-1-004

Laboratory safety Team work culture in laboratory, General Safety and lab-safety procedures, Chemical, electrical and UV safety, safe handling of toxic and hazardous chemicals, storage and disposal of chemicals etc. Common laboratory Instruments and applications: Principles and practices of instruments used in microbiology, biochemistry, molecular biology, genetics engineering, fermentation technology, bioremediation, plant biotechnology, ecology etc.

Final Draft

Paper II (Level 200) (Compulsory Paper) Biodiversity and Environmental Studies Per week L-T-P-C = 2-0-0-0.25 (Total L-T-P-C = 32-0-0-4) 4 months

200 level courses Course number

Course content

Bio-NEIST-2-001

Biodiversity and Environmental Studies (Compulsory Paper) Overview of Biodiversity and conservation: types of protected area, protected areas of N E India, Environmental and Forest policies and laws Scope of environmental studies, Environmental studies in a multidisciplinary approaches. Ecosystems – major types, structure and functions, productivity of ecosystems and sustenance.

Bio-NEIST-2-002

Natural resources Types of resources, basics of conservation, natural resources of N E India, Traditional knowledge with reference to natural resources and their application potential.

Bio-NEIST-2-003

Advance Plant Physiology: Introduction to plant biology, physiological and molecular responses of plant to abiotic stress, advances in mineral nutrition, photosynthesis and ecological adaptation.

Bio-NEIST-2-004

Biotransformation & Bioremediation: Microbial biotransformation, biodegradation of petroleum, xenobiotics, bioremediation and phyto-remediation, production of microbial enzymes and fermentation, physico-chemical parameters for maximum enzyme production, enzyme purification, characterization and immobilization of enzymes, enzyme use for biotransformation, chiral synthesis.

Bio-NEIST-2-005

Molecular Biology & Biotechnology: Isolation, purification and characterization of microbes. DNA Finger printing, Electrophoresis, PCR, Real Time PCR, Reverse Transcriptase PCR, Sequencing of DNA, basic knowledge and application of bioinformatics etc. Molecular basis of plant-microbe interactions and application of microbes in industry and agriculture.

Final Draft

Part B –Optional Courses Paper III (Level 300) Elective (to be chosen below) (20 credits) (any four papers of the following) Per week L-T-P-C = 3-1-1-0.166 (Total L-T-P-C = 72-24-24-4) 6 months

300 level courses Course number

Course content

Bio-NEIST-3-001

Microbial Biotechnology Isolation, screening of microbes for industrial and agriculture application, production of bioactive metabolites for pharmaceutical and industrial lead/hits, DNA fingerprinting, DNA sequencing, Molecular characterization of genes and traits responsible for biological activity, enzyme production, isolation, purification, characterization and applications. Exploitation of microbes for bioremediation & biotransformation.

Bio-NEIST-3-002

Advances in physiological and molecular responses to abiotic stress Plant ecology and stress physiology with basic concepts and approaches applicable to all types of plants. Emphasis on the relationship between environmental parameters (radiation, temperature, water, nutrients), heavy metals, and their effect on development, membranes, phytohormones, carbon balance, and the use of stable isotopes in stress, physiological processes (photosynthesis, respiration, cellular and molecular responses, mineral nutrition), and plant responses (leaf expansion, partitioning of dry mass, water status, and transpiration). Integration of plant responses into models for better understanding and predict growth and yield.

Bio-NEIST-3-003

Biodiversity and conservation Concept and definition of Biodiversity, existing regulations, laws and NBA, Bioprofiling, in-situ- and ex-situ preservation, Bio-prospection and utilization, Methods and Approaches for value additions, Role and Relevance of Biodiversity, Technology development and dissemination, Ecology and socioeconomic impact of local resources on stack-holders. Biotic and abiotic interaction, Impact of stress factors on Life forms, Climatic changes and agro biology, Adaptation Biology and Evolution, Ecotourism managements.

Final Draft

Bio-NEIST-3-004

Eco-restoration Ecology and nature of environmental degradation of ecosystems due to natural and manmade activity and different measures adopted for ecological restoration. Phenocopies and Ecotypes; genetic Assimilation and natural selection; Phenotypic Accommodation; Evolutionary considerations; Developmental mechanisms of phenotypic accommodation; Reciprocal accommodation, Niche construction

Bio-NEIST-3-005

Ethnobotany and Traditional Knowledge Ethnobotany, definition and scope, Role and relevance of Ethnobotany, Ethnobotany and medical botany, Interdisciplinary nature of Ethnobotany, Medical botany and drug development,Methods and approach of ethnobotany, Ethnobotany and plant taxonomy, Ethnobotany and bioprospection, Validation of Ethnobotanical knowledge, Cross cultural Ethnobotany, Plant folk medicines and NE India, Ethnobotany and biopiracy, Documentation and development of database.

Bio-NEIST-3-006

Plant - Insect Interaction and Herbivore Managements Herbivore-Plant Interaction. Tritrophic interactions of plant-insect & parasitodids,Plant defence Secondary plant metabolites, Botanical Pesticides past , present and future Plant-Pollinator interactions. Insect as pollinator- Honey bee & Butterfly as pollinator- Honeybee & crop production pollination Biology Butterfly as environmental indicator. Butterfly biodiversity, Host range, conservation Herbivores- induced plant defence. Induced biosynthesis of plant defense compounds-use of plant signal in agricultural crops- Transgenic plants. Insect behaviour. Manipulation of insect behaviour for insect pest management-Evolution of insect behavior Novel methods of Insect-pest management. IPM- Concept & Evolution, Ecology of pest- IPM of major pests, Resistance, Biocontrol/Biocides, Molecular approaches in Insect-pest Management.

Bio-NEIST-3-007

Advances in Plant Microbes Interactions Biology and Ecology of Plant Pathogens and Endophytes. Biology and ecology of major group of plant pathogens viz. fungi, bacteria, viruses, nematodes and mollicutes and endophytes. Concepts of plant diseases, etiology, microbial communities, virulence and resistance, population biology,

Final Draft

disease development and epidemiology. Genetics of Host Pathogen interaction and Mechanism of Host Defence. Genes and plant diseases, genetics of resistance and pathogenicity, recognition mechanisms in host pathogen interaction. Pathogenesis and host defence, passive and active defence mechanisms- structural and biochemical defences, systemic acquired resistance. Advances in Plant Disease Management. Introduction to biology of the pathogens that cause plant diseases, disease diagnosis. Topics include principles and practices of plant disease management including physical methods, regulatory methods, biological and chemical methods, host resistance and integrated plant disease management (IPDM). Biotechnology of Edible and Medicinal Mushroom. Prospects of edible and medicinal mushrooms , biochemistry of mushroom fructification, nutritive and medicinal values, spawn and spawn preparation, agrotechnology , pest and diseases ,genetic improvement. Bio-NEIST-3-008

Advance Plant Physiology Overview of Essential Concepts. Plant and cell Architecture, Energy and Enzymes Transport and Translocation of Water and Solutes. Water and Plant Cells, Water Balance of the Plant, Mineral Nutrition, Solute Transport. Biochemistry and Metabolism. Photosynthesis: The Light Reactions, Photosynthesis: Carbon Reactions, Photosynthesis: Physiological and Ecological Considerations, Translocation in the Phloem, Respiration and Lipid Metabolism, Assimilation of Mineral Nutrients, Plant Defences: Surface Protection and Secondary Metabolites. Growth and Development. Signal Transduction, Cell Walls: Structure, Biogenesis, and Expansion, Growth, Development, and Differentiation, Phytochrome, Blue Light, Responses: Stomatal Movements and Morphogenesis, Growth Hormones, the Control of Flowering, Stress Physiology

Bio-NEIST-3-009

Insect Biotechnology Isolation of protein/hormone from insects, insect tissues, In Vitro and In Vivo assays, Radiochemical Assays for detection of Hormones, Metabolism of Proteins, carbohydrates and silk protein biosynthesis, enzymes kinetics, microbial protein based products and process.

Final Draft

Bio-NEIST-3-0010

Molecular and cell biology Introduction to Molecular Biology, Historical background (Vital force theory, the scientific approach, classic experiments), Physico-chemical approach to biology,(Schrodinger's book, theory of the chemical bond, crystallography), Biomolecules and replication (DNA, RNA, protein, background to their discovery and analysis, roles played in biology, replication machinery in prokaryotes and eukaryotes, problem of packaging genetic information)., Flow of genetic information (Central dogma, adaptor hypothesis, operon concept, transcription, translation), Gene expression and control (Operon, cistron, polycistronic/monocistronic messages, transcriptional control, RNA processing, chromosomal histone modification, cell cycle), Evolution (organismal,bacterial, molecular, Darwin to Oparin, Hardy- Weinberg law, analysis of evidence, Cvalue paradox in eukaryotes, cot value), Cells and Biomolecules, Prokaryotic and eukaryotic cells overview and comparisons, Techniques for the study of cell structure and function (Histology, staining, karyotyping, freeze fracture, microscopy, FISH, flow cytometry, patch clamp, live cell imaging, probing with toxins), Microbial and phage genetics, (Discovery of the genetic material, Classic experiments in microbial and phage genetics - phage lysogeny, restriction and modification, bacterial conjugation, transformation, transduction) Cell components (cell wall, membrane, nucleus, mitochondria, chloroplasts, lysosomes, vacuoles, cytoskeleton), Protein sorting and secretion, biotechnological considerations (Golgi and ER, targeting of proteins, use of principles in high-expression systems)

Bio-NEIST-3-0011

Molecular Markers and Breeding Genome Organization Organellar genome and Nuclear Genome: Unique sequences, Repeat DNA sequences, Classification of Repeat DNA (Tandem repeats, Interspersed repeats, Micro-satellites, Mini-satellites, midi-satellites, VNTRs), The dynamic genome: Polymorphisms and Sources of Genetic variation, Oveview of Genetic Markers: Phenotypic Markers, Biochemical markers, DNA based markers Molecular marker and DNA fingerprinting techniques: Concepts, classification and methodologies: Hybridization based markers (viz. Restriction Fragment Length Polymorphism, Oligonucleotide fingerprinting), PCR based markers (viz. DNA Amplification Fingerprinting, Arbitrarily Primed PCR, Randomly Amplified Polymorphic DNA, SSRs, STMS, SCARs, Inter-SSRs, Multiple Arbitrary Amplicon Profiling, Amplified Fragment Length Polymorphism, electively Amplified Microsatellite Polymorphic Loci, Inter retrotransposon amplified polymorphism, retrotransposon-microsatellite amplified polymorphism, Diversity Array Technology (DArTs), SNPs and SNP based assays for high-throughput genotyping, EST based markers, Sequencing by Hybridization (SBH), Molecular Markers and Assessment of genetic diversity: Principles of Numerical taxonomy, binary matrix to phenetic dendograms, Structure analysis, Case Studies and examples, Molecular Markers for genome mapping: Principles of Genetics: Laws of inheritance, Linkage and crossing-over, Recombination analysis Genotyping Concepts for Genetic mapping Construction of genetic linkage maps for gene and QTL mapping, positional cloning for gene identification, Introduction to linkage mapping software packages and interfaces Breeding by design: Marker Assisted Selection (MAS), gene introgression and pyramiding, BSA Genotyping for Physical mapping: Fingerprinting for BAC assembly, Types of Mapping populations in Plants: F2 populations, RILs (recombinant inbred

Final Draft

lines), Backcross lines, NILS (Near Isogenic Lines), HIF (Heterogenous Inbred Families), AILs (Advanced Intercross Lines), Other Application of Molecular Markers: Genotyping tools as plant variety protection, hybrid purity tests, diagnostics (transgenics, forensics) Other Mapping tools and Methodologies: Introduction to Cytogenetic maps, Radiation Hybrid Maps, HAPPY mapping, Physical Maps, Comparative/Synteny mapping. Bio-NEIST-3-0012

Functional Genomics Gene Expression and the transcriptome analysis Medium throughput techniques. Northern, Quantitative RT-PCRs, RACEs, cDNA-AFLP, Inventories for gene discovery and annotation: EST databases, full-length cDNA /ORF clones Hi through put-genome wide Analytical Platforms. Microarrays: Whole Genome arrays, cDNA arrays and Tiling Arrays: Concept, designing, fabrication, probing, and data analysis, Applications: Global gene expression profiling, discovery of novel genetic pathways and targets, Genotyping for DNA polymorphism, Mapping genome wide epigenetic states, alternative splicing, miRNA microarrays, ChIPchips for identifying DNA binding sites. Hi through put-genome wide Profiling Platforms. Serial Analysis of Gene Expression, Digital Northerns, Massively Parallel Signture Sequences, Roche’s 454-FLX Sequencer, Solexa/Illumina’s 1G Genome Analyser Proteomics and integrative genomics. Protein separation and 2-D PAGE, Mass Spectrometry and protein identification: N-terminal sequencing, MALDI – TOF, LC-MS/MS, Tandem-MS/MS. SELDI-TOF, ICAT, I TRAQ, MUDPIT, Protein interaction maps, analysis of cellular constituents, metabolomics. Reverse genetics-Navigating from structure to Function Mutant analysis. Forward versus reverse genetic approaches, Mutagens and methodologies for Reverse genetic systems: Random and Targeted mutagenegis, Insertional Mutatagenesis viz. T-DNA tagging, Ac/Ds system for Transposon Tagging, TILLING, Deleteagene, Activation mutagenesis (Gene traps, Enhancer Traps and Promoter Traps), mis-expressions (viz ectopic expression, two component systems for tissue specific gene expression), RNAi based Silencing Techniques (viz. Antisense RNA, co-suppression, artificial miRNA, tissue or stage specific knockouts) Zinc-finger nucleases, Homologous Recombination, Genome-wide Mutant Libraries and resources. Genetic screens for molecular genetic analysis. Enhancer, suppressor and dominant modifier screens, Core-collections and germplasm resources for Reverse Genetics Natural Genetic Variation. Discovery of novel genes and alleles, Case studies from Rice and Arabidopsis Elucidation of molecular genetic Pathways and Processes. Flowering Time Control and flower development in Arabidopsis, Stress response and SOS pathways in Arabidopsis, Caenorhabditis elegans and Drosophila development, AtGenExpress: Transcriptome atlas of Arabidopsis thalianaCase Study

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Bio-NEIST-3-0013

Plant Biotechnology Management and Regulatory Issues Introduction to Legal System Constitution, Statutes, Rules, Regulations, Judicial System, Judicial Review, Administrative set up. International Law, Sources, Treaties Principles of Regulation Competing Models of Risk Assessment, Models of risk consideration: Scientific rationality trajectory and Social rationality trajectory. Risk Analysis Framework Risk Assessment, Risk Management and Risk Communication. The Concept of Precaution in Regulation Precautionary principle and precautionary approach Country Comparisons about Approaches to Biotechnology Regulation The U.S. and E.U. approaches on Biotechnology research, Intentional introduction into environment, GM Food, labelling etc. Multilateral Agreements. Convention on Biological Diversity, Cartagena Protocol on Biosafety, WTO Agreements, Codex Alimentarius, Plant Genetic Resources for Food and Agriculture. Regulatory Systems in India. Environment Protection Act, 1986 Rules for the manufacture, use, import, export and storage of hazardous micro-organisms, genetically engineered organisms or cells. Institutional Structure, Powers and Functions Relevant Guidelines and Protocols. Other relevant laws Plant Quarantine order Biological Diversity Act Protection of Plant Varieties and Farmer’s Rights Act Drugs and Cosmetics Act, Policy and the rules Seed Policy DGFT Notification Recent Initiatives Draft National Biotechnology Regulatory Bill 2008 IPRs Introduction. A Brief history of IP protection, Rationale for IPR, Types of IPRs, Patents, Copyright, Trademarks, Trade Secrets, Plant, Variety protection, Geographical Indications, Farmer’s, Rights, Traditional Knowledge Patents and Agricultural Biotechnology. Patentability criteria, Relevant Case law, Indian Patent Act, 1970, TRIPS, Amendments to Indian Patents Act (2005), IP applications and Procedures Patent drafting, Patent and prior art searches etc. Management of IPR Assets, Licensing and contracts, Negotiations, Valuation of patents, IPR Enforcement

AcSIR-NEIST-BS-400: 3-2-15-2 (Compulsory)  Project Proposal Writing  Seminar

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NIIST 100 level courses Course number BIO-NIIST-1O01

Course Content

Biostatistics Summarization of Data: measures of center, dispersion, skewness Dependence of variables: Correlation, linear regression, logistic regression Basic probability distributions: Binomial, Normal, Chi-squares. Estimation of parameters: method of moments, maximum likelihood Testing of hypotheses: (a) parametric tests: t-test, z-test, chi-squares test, ANOVA (b) non-parametric tests: Mann-Whitney, Kruskal Wallis, Kolmogorov-Smirnov

BIO-NIIST-1002

Computation/bioinformatics Computers: Introduction, Evolution and Classification of computers. Fundamentals of computing. Bit and Byte, Introduction to types of Hardware and Software. Components of Computer. Introduction to operating systems. Introduction to Computer Viruses. Network: Introduction. Network structure and architecture, Hierarchical networks, Ethernet and TCP/IP family of protocols, transport protocol design. Types of network, Topologies of network, Router, Switch, Data Communication, Concept of Wireless networking, LAN, WAN, MAN, Security of the network, Fire-walls, Network Applications Information Technology: Concepts of client Server Architecture, Concept of search Engine, Database search engines. Introduction to Internet Introduction to Word, Powerpoint and Excel Introduction to Bioinformatics: History of Bioinformatics, Genome sequencing projects, Human Genome Project, Applications of Bioinformatics. Introduction to databases, Type and kind of databases, Applications and limitations. Literature Search Databases, Nucleic acid and protein databases, Animal and plant databases, Ensembl Genome project TIGR database, Biotechnological databases, Motifs and Pattern Databases, Databases for species identification and classification, Structural databases. Database Retrieval and deposition systems. Web tools and resources for sequence analysis: Pairwise and multiple sequence Alignment, Sequence similarity search: BLAST, Pattern recognition, motif and family prediction, Restriction map analysis, primer design, Gene prediction, Phylogenetic Tree, Protein structure prediction and visualization.

BIO-NIIST-1003

Basic Chemistry Thermodynamics Solutions and Ions Chemical bonding and molecular structure Chemical Kinetics Stereochemistry Introduction to drug discovery (Medicinal chemistry approach) Drug target, discovery and development (forward and reverse approach

BIO-NIIST-1004

Research Methodology, Communication/ethics/safety Philosophy and structure of scientific thoughts, Objective and Motivation of Research,

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Meaning of the Research, What constitutes a research topic? How to select a research topic?, Importance of literature review, Selection of appropriate methodology, Collection of data, Interpretation of data, Writing research paper, Paper presentation in scientific conference, Statistical methods, Importance of documentation, Procedure for Hypothesis Testing, Values and Ethical Problems, Criteria of Good Research, Good laboratory practice, Chemical, Radioactive and Biological safety: Possible hazards and precautionary measures; do and don’ts upon exposure Research methodology, communication, ethics, safety Asking the right questions: Originality, Depth, Precision can co-exist Formulating and refining the hypothesis: Those who do not learn from the past are condemned to repeat it Study design: Recognizing and minimizing bias Experiment design: Sometimes less is more and the importance of controls Good lab practices: Record keeping, organizing data, organizing the lab space Data interpretation; objectivity, quantification, double blind studies and necessity of statistics Comunicating your data:writing up your research Comunicating your data: presenting your findings Radiation safety Chemical and Biosafety Intellectual property rights What is ethics, the different interpretations & historical instances of unethical science Case studies: Data fraud/ plagiarism and Human Ethics violation

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200 level courses Course number

Course Content

BIO-NIIST-2-001

Biotechniques and Instrumentation (compulsory) General Instrumentation: handling, care, usage and safety. Concepts of spectroscopy and use of UV-VIS spectrophotometers, Concepts of centrifugation, use of centrifuges, Electrophoretic equipments-ID and 2D electrophoresis and data analyses, Blotting techniques, Immuno-cytochemisty, ELISAs, PCR – equipment and techniques, RT-PCR, QPCR, chromatographic techniques- GC, LC and HPLC, Microscopy- Bright Field, Dark field, Phase contrast, fluorescence and confocal imaging, Electron microscopy, Concepts of DNA and protein sequencing and equipment for sequencing, Equipments for highthroughput assays – Micro-titer plate readers and multimode readers, ultra-filtration equipment.

BIO-NIIST-2-006

Protein Science and Proteomics Amino Acids and Proteins; Peptide backbone, side chains, polarity, Absorbance, Single letter codes etc. Protein Structure-Primary, secondary, tertiary and quaternary structure, covalent modifications of the polypeptide chain, Forces that determine protein structure, Structural motifs in regulatory proteins: DNA-binding proteins, Zinc finger motif, Helix Turn Helix motif Basic Leucine Zipper motifs. Tools: Databank of protein sequences (SWISS-PROT), Basics of protein sequence; alignment; Protein Regulation Enzymes I: Mechanism of Catalysis; Enzymes II: Kinetics & Regulation Protein Methods: Protein separation and purification Methods;Protein Function Analysis Practical Training to protein separation/detection using Western blotting; 1D and 2D Gel Electrophoresis: pI, Isoelectric focussing, 2 dimensional gel; Gel Staining methods and analysis Protein spot/Band processing for Mass spectrometric analysis Introduction to Mass spectrometers such as MALDI-TOF/TOF and electrospray mass spectrometer. Spectral Peak Annotation and Database search Shotgun Proteomics

BIO-NIIST-2-256

Basics and Applied Microbiology Isolation, Culture and Preservation of Microorganisms Streak plate method; pour plate method, pH, temperature and oxygen requirements. Cultivation of anaerobic bacteria, Isolation of soil algae. Aseptic handling of microbes including Sterilization (autoclaving). Culture Media: Solid and broth cultures shake cultures. Specific media for different group of microorganisms. Inoculum development, Methods of culture preservation- Refrigeration, Freezing, preservation in soil, freeze drying (Lyophilization, Principles of freeze drying- Predrying, ampoule preparation, harvesting the cultures, Primary drying, secondary drying, opening of ampoules Sterilization – concepts and methods Identification and classification of microbes- Colony characters, Staining methods, Biochemical tests, physiological tests and polyphasic approach. Classification based on extreme conditions like thermophiles, Alkaliphiles and halophiles Methods in applied microbiology Screening, primary, secondary, enrichment cultures Industrial Microbiology- Production of microbial Metabolites- organic acids, amino acids, antibiotics, enzymes, biopolymers. Microbial assisted processes, Immobilization techniques and processes

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employing immobilized whole cells. Strain improvement- Classical and modern techniques. Agricultural Microbiology – Role of microbes in plant health, plantmicrobe interactions, Biofertilizers, Biopesticides, PGPR. BIO-NIIST-2-257

Basic Molecular Biology Nucleic Acid Techniques -I Isolation of DNA (genomic, plasmid, bacterial, fungal, plant and mammalian), total RNA and mRNA. Gene cloning -prokaryotic and eukaryotic; Cloning strategies – shot gun cloning, PCR cloning, cDNA cloning. Cloning vectors –plasmids, viral vectors, phagemids, cosmids, fosmids, BAC vectors, YAC vectors, shuttle vectors, and expression vectors. Common host organisms used for genetic engineering. Construction of genomic and cDNA libraries. Gene transfer techniqueschemical transformation, electroporation, virus mediated transfer, Agarose gel electrophoresis for DNA separation, Denaturing gels for RNA Nucleic acid Techniques II PCR, RT-PCR, qPCR techniques and applications. Primer design – manual and using software, design of degenerate primers. DNA sequencing, primary analyses of sequences, nucleic acid databases searches, sequence deposition and access. Applications of nucleic acid base specificity in research – hybridizations, microarray techniques; Probes in nucleic acid detection –radioactive and non radioactive. Genomics –Functional, Comparative; High throughput analyses – Microarrays, Metagenomics, Applications of genomics.

BIO-NIIST-2-258

Bioprospecting and Biochemical Pharmacology Cellular organization and interaction i. Membrane structure and function: Structure of model membrane, lipid bilayer and membrane protein diffusion, osmosis, ion channels, active transport, ion pumps, mechanism of sorting and regulation of intracellular transport, electrical properties of membranes. ii. Cell division and cell cycle: Mitosis and meiosis, their regulation, steps in cell cycle, and control of cell cycle. iii. Cell signaling: Hormones and their receptors, cell surface receptor, signaling through G-protein coupled receptors, signal transduction pathways, second messengers, regulation of signaling pathways. iv. Cellular communication: General principles of cell communication, cell adhesion and roles of different adhesion molecules, gap junctions, extracellular matrix, integrins. Molecular Processes i. DNA replication, repair and recombination: ii. RNA synthesis and processing: iii. Protein synthesis and processing: iv. Control of gene expression at transcription and translation level Methods in Research i. Molecular biology methods: Isolation and purification of RNA , DNA (genomic and plasmid) and proteins, different separation methods; analysis of RNA, DNA and proteins by one and two dimensional gel electrophoresis, isoelectric focusing gels; RFLP, RAPD, AFLP techniques, PCR and RT-PCR. ii. Histochemical and Immunotechniques: Antibody generation, detection of molecules using ELISA, RIA, western blot, immune precipitation, flow cytometry and immune-fluorescence microscopy, detection of molecules in living cells, in situ localization by techniques such as FISH and GISH, HPLC, Ultra centrifugation. Chemistry of Natural Products i. Secondary Metabolites/ Alkaloids: Occurrence, isolation, classification

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and properties of alkaloids, structure determination, synthesis and physiological activities of ephedrine, nicotine, atropine and morphine. Terpenoids: occurrence, isolation, geraniol, citral, amyrin. ii. Phenolic compounds: Classification and properties. iii. Therapeutics: Bioactive principles in herbs, plants with hepatoprotective, hypoglycemic, anticancer, antibacterial, antiviral and antimalarial, anti-inflammatory properties. iv. Free radicals: Types, sources, importance, production, free radicals induced damages, lipid peroxidation, measurement of free radicals, disease caused by radicals, reactive oxygen species, antioxidant defence system, enzymic and nom-enzymic antioxidants, role of antioxidants in prevention of diseases ,phytochemicals as antioxidants. BIO-NIIST-2-259

Fundamentals of Food processing Thermal Processing of Foods Principles, Classification Cooking, blanching, pasteurization, sterilization, evaporation, extrusion, drying, Equipments and Applications Separations and concentration methods in food processing General Principle and application, Evaporation, Membrane processing, Reverse osmosis, Nanofiltration, Ultrafiltration, pervaporation, freeze drying , Extraction- liquid-liquid & solid liquid, Super critical extraction, Osmotic dehydration, Sedimentation, Equipments and Applications Separations and concentration methods in food processing General Principle and application, Evaporation, Membrane processing, Reverse osmosis, Nanofiltration, Ultrafiltration, pervaporation, freeze drying , Extraction- liquid-liquid & solid liquid, Super critical extraction, Osmotic dehydration, Sedimentation, Equipments and Applications Size reduction and its application in food industry Size reduction, Size measurement, Dry and wet grinding, Slicers/dicers, Pulpers and granulators, Milling equipments, Size separation Food Emulsions Basics and examples, Homogenizers and colloid mills- Principles, types and applications Mixing and Kneading Basics, Equipment and Applications Advances in Food processing Minimal processing, Hurdle technology,High pressure technology, Irradiation, Microwave, Cryogenics, Ohmic heating, Pulsed electric heating, ultrasound processing, Equipments and Applications Basic packaging Machinery Can sealing, Bottle washing, Filing and sealing, Powder fillers, Liquid fillers, Foam – fill and seal systems Sterilization techniques Basics, Techniques and Applications Maintenance of Food Plant & Equipment Maintenance of food plant and equipment, pumps, valves and conveyers

BIO-NIIST-2-260

Cell biology and Tissue Engineering Cellular organization Membrane structure and function: Structure of model membrane, lipid bilayer and membrane protein diffusion, osmosis, ion channels, active transport, ion pumps, mechanism of sorting and regulation of intracellular transport, electrical properties of membranes. iCell division and cell cycle: Mitosis and meiosis, their regulation, steps in cell cycle, and control of cell cycle. Cell signaling Basic Cell culture Types of cells grown in culture, work area and equipment, preservation and storage, maintenance, safety considerations, cell culture methods, determination of cell counts and viability, Cell based assays Animal cell culture

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Basic principles of cell culture, Preparation of culture lab, maintenance of aseptic conditions, biology of cells in culture, choice of materials, Generals methods of cell culture and parameters, monolayer culture, suspension culture, immobilized cultures, Cell line preservation and authentication: cell freezing, quantitation of recovery, authentication, Cytotoxicity and cell viability assays: specific techniques, end points, assay comparisons, protocols, interpretation, Flourescence in situ hybridization, Genetic modification: Basics of Transfection, microcell mediated chromosome transfer, irradiation fusion gene transfer, Stem cell identification, isolation and culture, Senescence, apoptosis and necrosis, Animal cell culture and drug designing.

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300 level courses Course number

Course Content

BIO-NIIST-3-001

Seminar course (compulsory)

BIO-NIIST-3-005

Introductive Bioinformatics Introduction to bioinformatics-Historical perspectives. Introduction to data mining, internet and bioinformatics, applications of data mining to bioinformatics problems and applications of bioinformatics. Sequence Alignments - Pair wise sequence alignments – Global and Local, Methods of alignment, Algorithms for sequence comparisons – Smith Waterman, Needlman and Wunsch , Dynamic Programming, Scoring matrices and gap penalties. Multiple sequence alignments – scoring multiple sequence alignments, methods for multiple sequence alignments. Tools for sequence alignment – web based and local – BLAST, Clustal W, BLOCKS. Phylogenetic prediction and analysis – methods, gene prediction. Biological databases and their interfaces-Types of databases, nucleotide database- Genebank, EMBL, PDBJ, Genes, Entrez. Protein sequence databases – Swiss Prot/ TrEMBL; Sequence motif/domain databases – Pfam, PROSITE; Protein sequence databases - PDB, CATH, SCOP. Protein classification and structure prediction - Conserved domains, motifs, structure function relationships, viewing protein structure; Protein sequence alignments, use of sequence pattern for structure prediction, prediction of secondary structures – tools, tertiary structure prediction by homology modeling. Applications of Bioinformatics - Phylogenetic analysis, Comparative genomics – functional genomics, Drug discovery, Gene expression analyses.

BIO-NIIST-3-011

Microbial Diversity and Ecology Microbial Taxonomy and Diversity: Bacteria, Archea and their broad classification; Eukaryotic microbes: Yeasts, molds and protozoa; Viruses and their classification; Molecular approaches to microbial taxonomy. Role of microbial life in the evolution and ecology of the biosphere, application of classical ecological concepts to microbial populations and communities, Underlying principles that drive microbial population structure in the environment, Community function and dynamics at both the molecular and the organismal level, Abiotic and biotic interactions within microbial communities, Ecophysiology and thermodynamic constraints on microbial community structure, Molecular and genomic tools for understanding the physiology and ecology of microbial communities, Microbial metabolism and biogeochemical cycling. Microbial interactions with the Environments: Interactions of microorganisms with their physical and chemical environment, biogeochemical cycles, Interactions with the biotic environment: symbiosis, competition, parasitism, predation, Interactions within microbial communities: quorum sensing, syntrophy, antibiotics, Interactions of microorganisms with algae and plants, Interactions of microorganisms with animals and humans. Methods in Microbial Ecology: Pure culture techniques, principles of microbial, nutrition, enrichment culture techniques for isolation of microorganisms. Characterization of microbial communities: PCR, sequencing, molecular fingerprints, Characterization of microbial communities: culture-based methods, biomarkers, cell stains, Characterization of microbial communities by culture independent molecular methods, Methods of extracting total bacterial DNA /RNA from a habitat: FISH, real-time PCR, DGGE, T-RFLP, SSCP, functional Clone library (metagenomics), pyrosequencing. Software tools in Metagenomics, Newer approaches for exploring

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uncultivable bacteria, methods in Taxonomy of Bacteria (including archae, bacteria,) and Fungi: Morphological Methods, Chemotaxonomy, Genetic Methods ,Methodology of rRNA, Methodology of identification of unknown pure cultures: Strategy and methods. BIO-NIIST-3-381

Bioprocess Technology Introduction to Bioprocess Technology; Introduction, microbial metabolites an overview (primary and secondary), Factors on growth and product formation, raw materials and media formulation, microbial growth curve and growth kinetics, sterilization, death kinetics. Fermentation Technology Types of Fermentation (submerged and solid state fermentation), Batch, fed batch and continuous modes of fermentation, Fermentation kinetics, Factors affecting fermentation process, Process parameter optimizations using statistical tools Bioreactors Introduction, Bioreactor configurations, design features, Sterile operations, Types of bioreactors (stirred tank, fluidized bed, packed columns, airlift etc), Bioreactors for submerged fermentation, Bioreactors for SSF, concepts of mass transfer, heat transfer, Engineering aspects in bioreactor designing. Downstream Processing Unit operations in downstream processing, concentration –filtration, flocculation, precipitation, chromatography techniques, dialysis, reverse osmosis, ultra filtration, electrophoresis, electrodialysis, crystallisation, drying, monitoring downstream process and process integration. Industrial Microbiology Characteristics of industrial micro organisms , Industrial applications of microbial biotechnology (production of organic acids, enzymes, amino acids, antibiotics etc), Industrial strain improvement, classical mutations, protoplasmic fusion, auxotrophic mutants, role of metabolic engineering in industrial biotechnology

BIO-NIIST-3-382

Enzymology & Enzyme Technology Introduction to Enzymology- Introduction to enzymes, modes of action, Classification and nomenclature of the enzymes- Oxidoreductase, Transferase, Hydrolase, Lyase, Isomerase, Ligase. Production and purification of enzymes- Industrial production of enzymes - Production methodology, Optimization of culture medium and production conditions, techniques used for enzyme homogenization, Down-stream processing. Techniques for enzyme assaysSpectrophotometric method, colorimetric method, fluorescence method, manometric method, viscometric method. Purification methods, Concentration of enzyme - Salting out using ammonium sulfate, fractionation using organic solvents, fractionation using non-ionic polymers, fractionation using polyelectrolyte etc, Dialysis, ultra-filtration., Chromatographic separation of enzymes – Adsorption chromatography, ion-exchange chromatography, affinity chromatography, gel filtration chromatography, chromatofocusing. Techniques for protein separation- paper electrophoresis, gel electrophoresis, capillary electrophoresis, isoelectric focusing. Crystallization of enzymes. Characterization of enzymes- Determination of temperature and pH optima, Determination of molecular weight of enzyme- gel filtration chromatography, PAGE, other methods. Enzyme inhibitors – competitive inhibition, non-competitive inhibition, mixed type of inhibition, uncompetitive inhibition. Kinetics of enzyme reaction- Concept of ES complex, active site, specificity, Mechanism of enzyme reaction, measurement of reaction velocity, Different plots for the determination of Km & Vmax and their

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physiological significances. Importance of Kcat/K m. Kinetics of zero & first order reactions. Significance and evaluation of energy of activation. Michaelis pH functions & their significance. Michaelis & Menten equation for uni-substrate reactions, Lineweaver–Burk plot, Hanes–Woolf plot, Scatchard equation. Immobilization of enzymes and industrial applications of enzymesMethods of immobilization- carrier binding method, physical adsorption method, ionic binding, covalent binding, cross linking method, entrapping method, microencapsulation. Industrial applications of enzymes – Food and baking industry, Textile industry, Leather industry, Detergent industry, paper and pulp industry, animal feed industry, therapeutic and diagnostic applications, enzymes in biofuel industry. BIO-NIIST-3-383

Biodegradable polymers Biodegradable polymers – Historical outline, Classification (natural and synthetic biopolymers). Important polyesters that have been commercialised and under commercialization such as PHA, PHB, PLA and others. Biopolymers-microbial production, Production processes, downstream processing Methods for characterisation of polymers (TLC, FTIR, GPC, Viscometric methods, NMR), structure, physio-chemical properties, Life cycle assessment biopolymer and applications. Production processes for biopolymer, Chemical modifications and its significance. Biotic and abiotic degradation of biopolymers. Microbial deterioration (aerobic and anaerobic). Biodegradability testing. Role of enzymes in biodegradation. Factors affecting biodegradation. Application of biopolymers- biodegradable plastics, tissue engineering, drug delivery.

BIO-NIIST-3-384

Metabolic Engineering Review of cellular metabolism (Transport processes, fuelling reactions, biosynthesis, growth energetic) Review of cellular stoichiometry. Regulation of metabolic pathways: Levels of regulation of enzymatic activity (overview of kinetics, reversible and irreversible inhibitions, allosteric enzymes and cooperativity) – regulation of enzymes concentration (Control of transcription and translation – example with respect of lacoperon and catabolite repression)- Global controlregulation of metabolic networks (Branch point classification, coupled reactions and global currency metabolities and energy regulation) Metabolic engineering in practice: Concept of directed cellular energy utilization – analytical and synthetic elements of metabolic engineering – targets of metabolic engineering. Metabolic Pathway analysis (Typical case study: Lysine Biosynthesis) Strategies for redirecting branched and linear pathways: (Alteration of feed back regulation; limiting accumulation of end product feedback resistant mutants, alteration of permeability). Metabolic Flux Analysis: Concept and utility of MFA – Theory – case studies – over determined systems – experimental determination of MFA by isotope labeling – applications of MFA: Case studies- concept & fundamentals of metabolic control analysis (Basic concept only). Application of pathway manipulations: Strategies for overproduction of primary metabolites. Strategies for overproduction of secondary metabolites (precursor effects, prophophase idiophase relationship,

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enzyme induction, feedback regulation.) Bioconversions: (ME concepts applied in process decisions for enhanced bioconversion). Examples of pathway manipulations: Enhancement of product yield (alcohol, amino acids)– extension of substrate ranges (lignocelluloses utilization) – extension of product spectrum (antibiotic, biopolymers) - improvement of cellular properties (alteration of metabolism, enhanced efficiency and yield, genetic stability).

BIO-NIIST-3-385

Natural Product Chemistry Structure, Bonding & Nomemclature Lewis structures, orbital hybridization, configuration and stereo chemical notation, conformational analysis, systematic IUPAC nomenclature. Functional Groups Preparation, reactions, and interconversions of alkanes, alkenes, alkynes, dienes, alkyl halides, alcohols, ethers, epoxides, sulfides, thiols, aromatic compounds, aldehydes, ketones, carboxylic acids and their derivatives, amines Reaction Mechanisms Nucleophilic displacements and addition, nucleophilic aromatic substitution, electrophilic additions, electrophilic aromatic substitutions, eliminations, Diels-Alder and other cyclo additions Reactive Intermediates Chemistry and nature of carbocations, carbanions, free radicals, carbenes, benzynes, enols Resonance, molecular orbital theory, catalysis, acid-base theory, carbon acidity, aromaticity, antiaromaticity. Natural products i. Carbohydrates-glucose- The structure and configuration of glucoseAnomeric forms of monosaccharides-glycosides-Disaccharides: cellobiose, maltose, gentibiose, trehalose ii. Polysaccharides-starch, cellulose, hemicellulose, modification of cellulose, Extraction, separation and quantification methods iii. Polyketides- biosynthesis-Acetyl Coenzyme-A, Orsellinic acid structure iv. Lipids:,Fatty acids, structure, reactions, extraction methods, saturated and unsaturated fatty acids oleic, linoleic, linolenic, PUFA, waxes, phospholipids v. Terpenoids-general –isolation methods- isoprene rule, biosynthesis ,monoterpenes alpha-pinene, beta-pinene, cineole, citrals, geraniol,sesquiterpenes, caryophyllenes, zingiberene, humulenes, nerolidols, farnesols, oxides of caryophyllene, diterpenes - abeitic acid, triterpenoids- sqalenes and carotenoids-beta carotene, capsanthins vi. Alkaloids: Biosynthesis structure, general classification, sources, isolation methods, properties-piperine, coniine, quinine vii. Steroids-general-cholesterol and sitosterols, isolation methods viii. Phenyl propanoids- biosynthesis general characteristics-coniferyl alcohol ix. Aminoacids – assay, isolation methods, alpha aminoacids-reactions, essential amino acids, Peptides& proteins –primary structure of peptides-assay x. Saponins-general, isolation methods, sources, properties, polyketides -general structure, properties, isolation techniques xi. Vitamins-general, classification, sources,V-A,V-B complex,V-C, structures, dietary importance, Assay for V-C,V-A and V-E

BIO-NIIST-3-386

Cardiovascular Disease Biology Pathophysiology of various heart diseases. Biochemical changes associated with myocardial infarction (MI) viz., oxidative stress, Lipid peroxidation and metabolic changes associated with MI. Risk factors associated with myocardial infarction. Biochemical risk

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factors, modifiable risk factors and non modifiable risk factors Physiology of cardiac function, Cardiac hypertrophy, various types of cardiac hypertrophy, pathophysiology. Molecular basis of cardiac hypertrophy, Ishcmeia/reperfusion injury Signaling pathways in cardiac hypertrophy, calcineurin-NFAT pathway, Cyclic GMP/PKG-1 pathway, G-protein coupled receptors, Gq/G11 signaling, Histone deacetylases, MAPK pathways Various systems involved in the pathophysiology of cardiac hypertrophy viz., Na/H Exchanger, Renin angiotensin system (RAS), Atrial natriuretic peptide (ANP), Nitric oxide, Tumor necrosis factor (TNF-alpha), Peroxisome proliferators activated receptor). Drugs that affect cardiac function, Cardiac angiogenesis, calcium transient in hypertrophy, calcium overload Thrombosis, Platelets and Anti-Platelet Therapy in Cardiovascular Disease: Molecular Mechanisms, Blood Coagulation and Atherothrombosis, Thrombosis and Thrombolytic therapy. Drugs that act on the coagulation cascade

BIO-NIIST-3-387

Molecular Biology of Diabetes Introduction to Diabetes Mellitus, Preclinical and Clinical Methods for Evaluating Antidiabetic Activity of Plants, in vitro Models for Assessing Antidiabetic Activity, Plant metabolites and other Antioxidant Polyphenols in alleviating diabetic complications Insulin Secretion in Type II Diabetes, cellular effects of insulin, insulin signalling pathways, regulation mechanisms Cellular Effects of Elevated Glucose Concentrations, regulation by Insulin and an Insulinomimetic Approach to Lowering Blood Glucose Levels, Insulin resistance, its importance in diabetes and tissues affected, Obesity and its link to diabetes Metabolic Aspects of Glycogen Synthase Activation and its role in the pathogenesis of Insulin Resistance and Hypoglycemia, the distinction between ‘Glucose set point’, ‘Glucose Threshold’and ‘Glucose Sensor’ is critical for understanding the role of the Pancreatic β-Cell in Glucose Homeostasis Mechanisms of Diabetic Complications, Oxidative Stress and Advanced Glycosylation End Products and Diabetic Retinopathy Drugs currently used in the treatment of Diabetes its proposed mechanism of action and reported side effects, therapeutic potential of recombinant gene transfer studies

BIO-NIIST-3-388

Environmental Technology Waste Characterization Organic and inorganic pollutants, Chemical oxygen demand (COD), Biological oxygen demand (BOD), Suspended solids (SS), Mixed liquor suspended solids (MLSS), Volatile suspended solids (VSS), Nutrient load, Total nitrogen (TN), Ammonia-nitrogen (NH4-N), Total phosphorus (TP), Microbial load, drinking water standards, discharge limits, Persistent organic pollutants, Ambient air quality, Air quality monitoring, VOC emission factor. Biological Waste Water Treatment Biological wastewater treatment, waste air treatment, biofilters, anaerobic digestion, composting, aerobic, anoxic and anaerobic wastewater treatment, combined treatment systems, soil remediation, phytoremediation, constructed wet lands, lake remediation Process parameters in engineered biological systems Batch, Fed-batch and continuous bioreactors, Sequence-batch reactor (SBR), Fluidized bed and packed bed bioreactors, Photo-bioreactor, Upflow anaerobic sludge blanket reactors (UASB), Flocculated and granular sludge, Hydrolic retention time (HRT), Solid retention time (SRT), Pollutant loading rate, Microbial growth kinetics Molecular Microbial Analysis

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Microbial community analysis in waste treatment systems, Molecular markers for microbial diversity analysis, Fluorescent microscopy, Whole cell fluorescent in-situ hybridization (FISH), PCR, DGGE/TGGE, rep-PCR, 16S DNA sequence analysis and phylogenetic analysis, protein profiling. BIO-NIIST-3-389

Biomass to fuels To recognize the diversity of plants, plant parts and plant structures that provide raw material for biofuel production. To understand basic principles of plant light energy conversion to chemical energy and carbon fixation. C3 and C4 plants. To examine the basic chemistry and biochemistry involved in the conversion of sugars to liquid alcohol Ecological dimensions of biofuels Impact of biofuels in global climate change and food production Case Study: Corn, cellulosic and sugar cane ethanol pros and cons Starch-Corn-ethanol: Resources and energy consumed by the industry: water, fertilizer and pesticides. Biorefineries & distribution, transport and green house gas emissions, denaturation with gasoline, distribution Cellulose stocks for biofuel, mill residues, forest residues, and agriculture waste. Cellulose-ethanol pathway starting from degradation of the plant cell wall, pretreatments to make biomass more accessible to enzymatic attack, hydrolysis of cellulose to glucose and conversion to ethanol. Lignin problem

BIO-NIIST-3-390

Biochemical Engineering Introduction to Engineering calculations. Energy and Material Balances Unit operations and unit processes: historical and more recent developments in chemical engineering; Process variables and degrees of freedom; Differential and integral balances; Lumped and distributed balances; Balances in systems involving physical changes Steady state energy and material balances Balances in reacting systems; Balances in systems involving recycle, purge, and bypass; Computer aided calculations; Generalization to unsteady state balances Introduction to transport phenomena: Momentum transfer Viscosity; Molecular theory of Gases and Liquids; Shell balance: Falling film, Circular tube; Equations of Change for isothermal systems: Continuity, Motion, Energy, Substantial derivatives; Unidirectional flows: Pipe flow, Variable viscosity falling film, Couette viscometer, Rotating Sphere; Unsteady flows: Startup Plate flow, Parallel plates etc Introduction to transport phenomena: Heat & Mass transfer Thermal conductivity and mechanism of energy transport; Shell energy balances and temperature distributions in solids and laminar flow; Diffusivity and the mechanisms of mass transport; Concentration distributions in solids and laminar flow; Equations of change for multicomponent systems; Introduction to the concept of heat and mass transfer coefficients; Dimensional Analysis Reactor Engineering- Bioreactor configurations

Final Draft

Annexure III-B

Course Content of Chemical Sciences

Special Meeting of Senate 08.06.2012

Final Draft

AcSIR-Chemical Cluster 1. 2. 3. 4. 5. 6.

Final Draft

CSIR-CECRI CSIR-CSMCRI CSIR-IICT CSIR-IIP CSIR-NCL CSIR-NIIST

100 level courses 101 and 102/103 compulsory CHE-LAB-1-001 Research Methodology: 1-0-0-1 CHE-LAB-1-002 Analytical Tools and Instrumentation: 1-0-0-1 Or CHE-LAB-1-003 Basic mathematics and numerical methods: 1-0-0-1 CHE-LAB-1-004* (*Optional course) Basic Chemistry for Interdisciplinary sciences: 1-0-0-1 CHE-LAB-1-005* (*Optional course) Introduction to Nanoscience and Nanotechnology: 1-0-0-1 CHE-LAB-1-006* (*Optional course) Introduction to Chemical Biology: 1-0-0-1 *Optional courses, over and above minimum requirements

200 level courses 201/202/203 compulsory (Core) CHE-LAB-2-001 Advanced Physical Chemistry: 2-0-0-2 CHE-LAB-2-002 Advanced Inorganic Chemistry: 2-0-0-2 CHE-LAB-2-203 Advanced Organic Chemistry: 2-0-0-2 CHE-LAB-2-004 Advanced Analytical Chemistry: 2-0-0-2 CHE-LAB-2-005 Advanced Quantum Mechanics: 2-0-0-2 CHE-LAB-2-006 Advanced Organometallic Chemistry: 2-0-0-2 CHE-LAB-2-007 Advanced Coordination Chemistry: 2-0-0-2 CHE-LAB-2-008 Advanced Photochemistry: 2-0-0-2 CHE-LAB-2-009 Advanced Polymer Chemistry: 2-0-0-2 CHE-LAB-2-010 Advanced Electrochemistry: 2-0-0-2

Final Draft

CHE-LAB-2-011 Advances in Bioinorganic chemistry: 2-0-0-2 CHE-LAB-2-012 Advances in hydrocarbon chemistry: 2-0-0-2 CHE-LAB-2-013 Advanced process chemistry: 2-0-0-2 CHE-LAB-2-014 Advanced Materials Science: 2-0-0-2 CHE-LAB-2-015 Advanced Catalysis: 2-0-0-2 CHE-LAB-2-016 Advanced Surface Science: 2-0-0-2 CHE-LAB-2-017 Advanced Separation Science and Technology: 2-0-0-2 CHE-LAB-2-018 Advanced Materials Characterization Techniques: 2-0-0-2 CHE-LAB-2-019 Advances in Nanoscience and Nanotechnology: 2-0-0-2 CHE-LAB-2-020 Advances in soft matter chemistry: 2-0-0-2 CHE-LAB-2-021 Advances in Chemical Biology: 2-0-0-2 CHE-LAB-2-022 Advanced Biomaterials: 2-0-0-2 CHE-LAB-2-023 Rare Earth Chemistry: 2-0-0-2 CHE-LAB-2-024 Sol-gel chemistry: 2-0-0-2 CHE-LAB-2-025 Combinatorial chemistry: 1-0-0-1 CHE-LAB-2-026 Green chemistry: 1-0-0-1 CHE-LAB-2-027 Coal chemistry: 2-0-0-2 CHE-LAB-2-028 Alternative feedstock options for petrochemicals: 2-0-0-2 CHE-LAB-2-029 Natural products: 2-0-0-2 CHE-LAB-2-030 Ionic liquids: 1-0-0-1

Final Draft

CHE-LAB-2-031 Synthetic methods for organic chemists: 2-0-0-2 CHE-LAB-2-032 Organic reaction mechanisms: 2-0-0-2 CHE-LAB-2-033 Dyes and pigments: 1-0-0-1 CHE-LAB-2-034 Physical organic chemistry: 2-0-0-2 CHE-LAB-2-035 Thermodynamics and Statistical Mechanics: 2-0-0-2 CHE-LAB-2-036 Composite materials: 2-0-0-2 CHE-LAB-2-037 Carbon allotropes: 1-0-0-1 CHE-LAB-2-038 Organic spectroscopy applications: 2-0-0-2 CHE-LAB-2-039 Surface characterization techniques: 2-0-0-2

300 Level courses CHE-LAB-3-001 Mathematical Methods: 2-0-0-2 CHE-LAB-3-002 Numerical Methods: 2-0-0-2 CHE-LAB-3-003 Electronic structure theory: 2-0-0-2 CHE-LAB-3-004 Molecular modeling and simulation: 2-0-0-2 CHE-LAB-3-005 Computer aided drug design: 2-0-0-2 CHE-LAB-3-006 Computational materials design: 2-0-0-2 CHE-LAB-3-007 Multiphase reaction kinetics: 1-0-0-1 CHE-LAB-3-008 Carbohydrate chemistry: 2-0-0-2 CHE-LAB-3-009 Biophysical chemistry: 2-0-0-2 CHE-LAB-3-010 Physics and chemistry of collagen: 2-0-0-2

Final Draft

CHE-LAB-3-011 Marine Natural products: 2-0-0-2 CHE-LAB-3-012 Supramolecular chemistry : 2-0-0-2 CHE-LAB-3-013 Total Synthesis: 1-0-0-1 CHE-LAB-3-014 Asymmetric Syntheis: 1-0-0-1 CHE-LAB-3-015 Chemistry and biology of Heterocycles: 2-0-0-2 CHE-LAB-3-016 Agrochemicals: 2-0-0-2 CHE-LAB-3-017 Fluoro organic chemistry: 2-0-0-2 CHE-LAB-3-018 Corrosion science: 2-0-0-2 CHE-LAB-3-019 Nutraceuticals: 2-0-0-2 CHE-LAB-3-020 Salts from marine resources: 2-0-0-2 CHE-LAB-3-021 Ionic liquids for lubricants: 1-0-0-1 CHE-LAB-3-022 Applications of ionic liquids: 1-0-0-1 CHE-LAB-3-023 Homogeneous Catalysis: 1-0-0-1 CHE-LAB-3-024 Catalysis in petroleum refining: 2-0-0-2 CHE-LAB-3-025 Catalysis for organic synthesis: 1-0-0-1 CHE-LAB-3-026 Catalysis for biomass refining: 1-0-0-1 CHE-LAB-3-027 Biocatalysis in petroleum refining: 1-0-0-1 CHE-LAB-3-028 Materials and devices for energy conversion: 2-0-0-2 CHE-LAB-3-029 Functional Ceramics: 1-0-0-1 CHE-LAB-3-030 Modern Magnetic Materials: 1-0-0-1

Final Draft

CHE-LAB-3-031 Porous structures: 2-0-0-2 CHE-LAB-3-032 Biomaterials for targeted therapeutics : 2-0-0-2 CHE-LAB-3-033 Organic electrochemistry: 2-0-0-2 CHE-LAB-3-034 Electrochemical power sources: 2-0-0-2 CHE-LAB-3-035 Alternate energy materials: 2-0-0-2 CHE-LAB-3-036 Photoinduced electron and Energy transfer: 2-0-0-2 CHE-LAB-3-037 Hydrogen generation and storage: 2-0-0-2 CHE-LAB-3-038 Thermochemical Conversion of Biomass: 1-0-0-1 CHE-LAB-3-039 CO2 sequestration and conversion: 2-0-0-2 CHE-LAB-3-040 Natural gas to liquid fuels: 2-0-0-2 CHE-LAB-3-041 Gasoline reformulation techniques: 2-0-0-2 CHE-LAB-3-042 Block copolymers: 2-0-0-2 CHE-LAB-3-043 Polymers for membrane applications: 2-0-0-2 CHE-LAB-3-044 Ion exchange polymers: 1-0-0-1 CHE-LAB-3-045 Conducting polymers: 1-0-0-1 CHE-LAB-3-046 Polymers and Colloidal Solutions: 2-0-0-2 CHE-LAB-3-047 Biodegradable polymers: 2-0-0-2 CHE-LAB-3-048 Controlled Radical/Living Polymerizations and Macromolecular Architectures: 2-0-0-2 CHE-LAB-3-049 Pi-conjugated polymers: 2-0-0-2 CHE-LAB-3-050 Liquid Crystals: 2-0-0-2

Final Draft

CHE-LAB-3-051 X-Ray Diffraction and Structure of Solids: 2-0-0-2 CHE-LAB-3-052 NMR spectroscopy: 2-0-0-2 CHE-LAB-3-053 Mass spectrometry applications: 2-0-0-2 CHE-LAB-3-054 Ultrafast processes and spectroscopy: 2-0-0-2 CHE-LAB-3-055 Small Angle Scattering Techniques: 2-0-0-2 CHE-LAB-3-056 Natural products and drug discovery: 2-0-0-2 CHE-LAB-3-057 Lipid science & technology: 2-0-0-2 CHE-LAB-3-058 Photobiology: 2-0-0-2 CHE-LAB-3-059 Nanobiotechnology: 1-0-0-1

400 level courses Compulsory courses CHE-LAB-4-001 Project proposal writing & presentation: 0-0-4-2 CHE-LAB-4-002 Project proposal writing & presentation: 0-0-4-2 CHE-LAB-4-003 CSIR-800: 0-0-8-4

Final Draft

CSIR-CENTRAL ELECTROCHEMICAL RESEARCH INSTITUTE, KARAIKUDI

100 Level Courses CHE-CECRI-1-001 Research Methodology: 1-0-0-1 CHE-CECRI-1-003 Basic mathematics and numerical methods: 1-0-0-1 CHE-CECRI-1-005* (*Optional course) Introduction to Nanoscience and Nanotechnology: 1-0-0-1 CHE-CECRI-1-006* (*Optional course) Introduction to Chemical Biology: 1-0-0-1 *Optional courses, over and above minimum requirements

200 Level Courses CHE-CECRI-2-001

Advanced Physical Chemistry: 2-0-0-2 CHE-CECRI-2-004 Advanced Analytical Chemistry: 2-0-0-2 CHE-CECRI-2-010 Advanced Electrochemistry: 2-0-0-2 CHE-CECRI-2-014 Advanced Materials Science: 2-0-0-2 CHE-CECRI-2-016 Advanced Surface Science: 2-0-0-2 CHE-CECRI-2-018 Advanced Materials Characterization Techniques: 2-0-0-2 CHE-CECRI-2-019 Advances in Nanoscience and Nanotechnology: 2-0-0-2 CHE-CECRI-2-022 Advanced Biomaterials: 2-0-0-2 CHE-CECRI-2-030 Ionic liquids: 1-0-0-1 CHE-CECRI-2-034 Physical organic chemistry: 2-0-0-2 CHE-CECRI-2-039 Surface characterization techniques: 2-0-0-2

Final Draft

300 Level Courses CHE-CECRI-3-006 Computational materials design: 2-0-0-2 CHE-CECRI-3-012 Supramolecular chemistry : 2-0-0-2 CHE-CECRI-3-018 Corrosion science: 2-0-0-2 CHE-CECRI-3-028 Materials and devices for energy conversion: 2-0-0-2 CHE-CECRI-3-033 Organic electrochemistry: 2-0-0-2 CHE-CECRI-3-034 Electrochemical power sources: 2-0-0-2 CHE-CECRI-3-035 Alternate energy materials: 2-0-0-2 CHE-CECRI-3-036 Photoinduced electron and Energy transfer: 2-0-0-2 CHE-CECRI-3-037 Hydrogen generation and storage: 2-0-0-2 CHE-CECRI-3-043 Polymers for membrane applications: 2-0-0-2 CHE-CECRI-3-045 Conducting polymers: 1-0-0-1 CHE-CECRI-3-059 Nanobiotechnology: 1-0-0-1

Additional Courses suggested by CECRI Polymer Electrolyte Fuel Cell 2-0-0-2 Advanced Lithium Batteries 2-0-0-2 Functional Materials 2-0-0-2 Electrochemical Technology 2-0-0-2 Advanced Corrosion Technology 2-0-0-2 Electrochemical Remediation 2-0-0-2 Final Draft

400 Level Courses CHE-CECRI-4-001 Project proposal writing & presentation: 0-0-4-2 CHE-CECRI-4-002 Project proposal writing & presentation: 0-0-4-2 CHE-CECRI-4-003 CSIR-800: 0-0-8-4

Final Draft

CSIR-CSMCRI 100 level courses 001 and 002/003 are compulsory i) ii) iii) iv) v)

CHE- CSMCRI-: 1-001: CHE- CSMCRI-: 1-002: CHE- CSMCRI-: 1-003: CHE- CSMCRI-: 1-004* CHE- CSMCRI-: 1-005*

Research Methodology: 1-0-0-1 Analytical Tools and Instrumentation: 1-0-0-1 Basic mathematics and numerical methods: 1-0-0-1 Basic Chemistry for Interdisciplinary sciences: 1-0-0-1 Introduction to Nanoscience and Nanotechnology: 1-0-0-1

(*Optional course)

200 level courses 001/002/003 compulsory (Core) i) ii) iii) iv) v) vi) vii) viii) ix) x) xi) xii) xiii) xiv) xv) xvi) xvii) xviii) xix)

CHE-CSMCRI-: 2-001: CHE-CSMCRI-:2-002: CHE-CSMCRI-: 2-003: CHE-CSMCRI-: 2-004: CHE-CSMCRI-:2-005: CHE-CSMCRI-:2-007: CHE-CSMCRI-: 2-009: CHE-CSMCRI-: 2-010: CHE-CSMCRI-:2-013: CHE-CSMCRI-:2-014: CHE-CSMCRI-: 2-015: CHE-CSMCRI-: 2-016: CHE-CSMCRI-:2-017: CHE-CSMCRI-: 2-018: CHE-CSMCRI-:2-019: CHE-CSMCRI-: 2-026: CHE-CSMCRI-: 2-029: CHE-CSMCRI-:2-030: CHE-CSMCRI-:2-032:

Advanced Physical Chemistry: 2-0-0-2 Advanced Inorganic Chemistry: 2-0-0-2 Advanced Organic Chemistry: 2-0-0-2 Advanced Analytical Chemistry: 2-0-0-2 Advanced Quantum Mechanics: 2-0-0-2 Advanced Coordination Chemistry: 2-0-0-2 Advanced Polymer Chemistry: 2-0-0-2 Advanced Electrochemistry: 2-0-0-2 Advanced process chemistry: 2-0-0-2 Advanced Materials Science: 2-0-0-2 Advanced Catalysis: 2-0-0-2 Advanced Surface Science: 2-0-0-2 Advanced Separation Science and Technology: 2-0-0-2 Advanced Materials Characterization Techniques: 2-0-0-2 Advances in Nanoscience and Nanotechnology: 2-0-0-2 Green chemistry: 1-0-0-1 Natural products: 2-0-0-2 Ionic liquids: 1-0-0-1 Organic reaction mechanisms: 2-0-0-2

300 Level courses i) ii) iii) iv) v) vi) vii) viii) ix) x) xi) xii) xiii) xiv) xv) xvi) xvii) xviii)

Final Draft

CHE-CSMCRI-3-004: CHE-CSMCRI-3-011: CHE-CSMCRI-3-012: CHE-CSMCRI-3-014: CHE-CSMCRI-3-020: CHE-CSMCRI-3-022: CHE-CSMCRI-3-023: CHE-CSMCRI-3-025: CHE-CSMCRI-3-026: CHE-CSMCRI-3-031: CHE-CSMCRI-3-034: CHE-CSMCRI-3-035: CHE-CSMCRI-3-036: CHE-CSMCRI-3-038: CHE-CSMCRI-3-039: CHE-CSMCRI-3-042: CHE-CSMCRI-3-043: CHE-CSMCRI-3-044:

Molecular modeling and simulation: 2-0-0-2 Marine Natural products: 2-0-0-2 Supramolecular chemistry : 2-0-0-2 Asymmetric Syntheis: 1-0-0-1 Salts from marine resources: 2-0-0-2 Applications of ionic liquids: 1-0-0-1 Homogeneous Catalysis: 1-0-0-1 Catalysis for organic synthesis: 1-0-0-1 Catalysis for biomass refining: 1-0-0-1 Porous structures: 2-0-0-2 Electrochemical power sources: 2-0-0-2 Alternate energy materials: 2-0-0-2 Photoinduced electron and Energy transfer: 2-0-0-2 Thermochemical Conversion of Biomass: 1-0-0-1 CO2 sequestration and conversion: 2-0-0-2 Block copolymers: 2-0-0-2 Polymers for membrane applications: 2-0-0-2 Ion exchange polymers: 1-0-0-1

xix) xx) xxi)

CHE-CSMCRI-3-045: CHE-CSMCRI-3-051: CHE-CSMCRI-3-052:

Conducting polymers: 1-0-0-1 X-Ray Diffraction and Structure of Solids: 2-0-0-2 NMR spectroscopy: 2-0-0-2

400 level courses Compulsory courses i) CHE-CSMCRI-4-001: ii) CHE-CSMCRI-4-002: iii) CHE-CSMCRI-4-003:

Final Draft

Project proposal writing & presentation: 0-0-4-2 Project proposal writing & presentation: 0-0-4-2 CSIR-800: 0-0-8-4

CSIR-IICT AcSIR PhD Program - 2011 Academic Session: August-December - 2011 Courses Offered in Academic Session: August-December – 2011 100 level courses 1. AcSIR-IICT-CS-101: Communication and Writing Skill: 2-0-0-2 2.

AcSIR-IICT-CS-102: Analytical Techniques : 2-0-0-2

200 level courses 1 AcSIR-IICT-CS-201: Frontier Organic Chemistry: 4-0-0-4 2

AcSIR-IICT-CS-202: Frontier Inorganic Chemistry: 4-0-0-4

3

AcSIR-IICT-CS-203: Frontier Physical Chemistry: 4-0-0-4

Final Draft

CSIR-IICT AcSIR PhD Program - 2012 Academic Session: February-July - 2012 List of Courses Academic Session: February-July - 2012 Chemical Sciences

CHE (IICT) - 100 level courses

1. CHE-IICT-1-002: Analytical Tools and Instrumentation: 1-0-0-1

2. CHE-IICT-1-005 (optional): Introduction to Nanoscience and Nanotechnology: 1-0-0-1

CHE (IICT) - 200 level courses 1.

CHE-IICT-2-001: Advanced Physical Chemistry: 2-0-0-2

2.

CHE-IICT-2-003: Advanced Organic Chemistry: 2-0-0-2

3.

CHE-IICT-2-004: Advanced Analytical Chemistry: 2-0-0-2

4.

CHE-IICT-2-009: Advanced Polymer Chemistry: 2-0-0-2

5.

CHE-IICT-2-015: Advanced Catalysis: 2-0-0-2 .

6.

CHE-IICT-2-017: Advanced Separation Science and Technology: 2-0-0-2

7.

CHE-IICT-2-019: Advances in Nanoscience and Nanotechnology: 2-0-0-2

8.

CHE-IICT-2-020: Advances in soft matter chemistry: 2-0-0-2

9.

CHE-IICT-2-026: Green chemistry: 2-0-0-2

10. CHE-IICT-2-033: Dyes and pigments: 1-0-0-1 11. CHE-IICT-2-036: Composite materials: 2-0-0-2 .

CHE (IICT) - 300 level courses 1.

CHE-IICT-3-012: Supramolecular chemistry : 2-0-0-2

2.

CHE-IICT-3-013: Total Synthesis: 1-0-0-1

3.

CHE-IICT-3-014: Asymmetric Synthesis: 1-0-0-1

4.

CHE-IICT-3-016: Agrochemicals: 2-0-0-2

5.

CHE-IICT-3-017: Fluoro Organic Chemistry: 2-0-0-2

6.

CHE-IICT-3-018: Corrosion science: 2-0-0-2

7.

CHE-IICT-3-026: Catalysis for biomass refining: 1-0-0-1

8.

CHE-IICT-3-028: Materials and devices for energy conversion: 2-0-0-2

9.

CHE-IICT-3-034: Electrochemical power sources: 2-0-0-2

10. CHE-IICT-3-037: Hydrogen generation and storage: 2-0-0-2 Final Draft

11. CHE-IICT-3-039: CO2 sequestration and conversion: 2-0-0-2 12. CHE-IICT-3-042: Block copolymers: 2-0-0-2 13. CHE-IICT-3-045: Conducting polymers: 1-0-0-1 14. CHE-IICT-3-046: Polymers and Colloidal Solutions: 2-0-0-2 15. CHE-IICT-3-048: Controlled Radical/Living Polymerizations and Macromolecular Architectures: 2-0-0-2 16. CHE-IICT-3-049: Pi-conjugated polymers: 2-0-0-2 17. CHE-IICT-3-050: Liquid Crystals: 2-0-0-2 18. CHE-IICT-3-051: X-Ray Diffraction and Structure of Solids: 2-0-0-2 19. CHE-IICT-3-052: NMR spectroscopy: 2-0-0-2: 20. CHE-IICT-3-053: Mass spectrometry applications: 2-0-0-2

Final Draft

CSIR IIP List of Courses for Chemical Sciences 100 level courses 001 and 002/003 compulsory CHE-IIP-1-001 Research Methodology: 1-0-0-1 CHE-IIP-1-002 Analytical Tools and Instrumentation: 1-0-0-1

200 level courses CHE-IIP-2-003 Advanced Organic Chemistry: 2-0-0-2 CHE-IIP-2-004 Advanced Analytical Chemistry: 2-0-0-2 CHE-IIP-2-012 Advances in hydrocarbon chemistry: 2-0-0-2 CHE-IIP-2-015 Advanced Catalysis: 2-0-0-2 CHE-IIP-2-028 Alternative feedstock options for petrochemicals: 2-0-0-2

300 Level courses CHE-IIP-3-007 Multiphase reaction kinetics: 1-0-0-1 CHE-IIP-3-021 Ionic liquids for lubricants: 1-0-0-1 CHE-IIP-3-024 Catalysis in petroleum refining: 2-0-0-2 CHE-IIP-3-027 Biocatalysis in petroleum refining: 1-0-0-1 CHE-IIP-3-038 Thermochemical Conversion of Biomass: 1-0-0-1 CHE-IIP-3-039 CO2 sequestration and conversion: 2-0-0-2 CHE-IIP-3-040 Natural gas to liquid fuels: 2-0-0-2 CHE-IIP-3-041 Gasoline reformulation techniques: 2-0-0-2

Final Draft

400 level courses Compulsory courses CHE-IIP-4-001 Project proposal writing & presentation: 0-0-4-2 CHE-IIP-4-002 Project proposal writing & presentation: 0-0-4-2 CHE-IIP-4-003 CSIR-800: 0-0-8-4

Final Draft

CSIR-National Chemical Laboratory 100 level courses 001 and 002/003 compulsory CHE(NCL):1-001: Research Methodology: 2-0-0-2 CHE(NCL):1-002: Analytical Tools and Instrumentation: 2-0-0-2 Or CHE(NCL):1-003: Basic mathematics and numerical methods: 2-0-0-2 CHE(NCL):1-004: Basic Chemistry for Interdisciplinary sciences: 1-0-0-1 CHE(NCL):1-005: Introduction to Nanoscience and Nanotechnology: 1-0-0-1 CHE(NCL):1-006: Introduction to Chemical Biology: 1-0-0-1

200 level courses 001/002/003 compulsory (Core) CHE(NCL):2-001: Advanced Physical Chemistry: 3-0-0-3 CHE(NCL):2-002: Advanced Inorganic Chemistry: 3-0-0-3 CHE(NCL):2-003: Advanced Organic Chemistry: 3-0-0-3 CHE(NCL):2-004: Advanced Analytical Chemistry: 3-0-0-3 CHE(NCL):2-005: Advanced Quantum Mechanics: 3-0-0-3 CHE(NCL):2-006: Advanced Organometallic Chemistry: 3-0-0-3 CHE(NCL):2-008: Advanced Photochemistry: 2-0-0-2 CHE(NCL):2-009: Advanced Polymer Chemistry: 3-0-0-3 CHE(NCL):2-010: Advanced Electrochemistry: 2-0-0-2 CHE(NCL):2-014: Advanced Materials Science: 3-0-0-3 CHE(NCL):2-015: Advanced Catalysis: 3-0-0-3 CHE(NCL):2-016: Advanced Surface Science: 2-0-0-2 CHE(NCL):2-017: Advanced Separation Science and Technology: 2-0-0-2 Final Draft

CHE(NCL):2-018: Advanced Materials Characterization Techniques: 3-0-0-3 CHE(NCL):2-019: Advances in Nanoscience and Nanotechnology: 3-0-0-3 CHE(NCL):2-021: Advances in Chemical Biology: 3-0-0-3 CHE(NCL):2-022: Advanced Biomaterials: 3-0-0-3 CHE(NCL):2-026: Green chemistry: 3-0-0-3 CHE(NCL):2-032: Organic reaction mechanisms: 3-0-0-3 CHE(NCL):2-035: Thermodynamics and Statistical Mechanics: 3-0-0-3 CHE(NCL):2-036: Composite materials: 2-0-0-2 CHE(NCL):2-037: Carbon allotropes: 1-0-0-1 CHE(NCL):2-038: Organic spectroscopy applications: 3-0-0-3 CHE(NCL):2-039: Surface characterization techniques: 2-0-0-2

300 Level courses CHE(NCL):3-001: Mathematical Methods: 2-0-0-2 CHE(NCL):3-002: Numerical Methods: 2-0-0-2 CHE(NCL):3-003: Electronic structure theory: 2-0-0-2 CHE(NCL):3-004: Molecular modeling and simulation: 2-0-0-2 CHE(NCL):3-006: Computational materials design: 2-0-0-2 CHE(NCL):3-008: Carbohydrate chemistry: 2-0-0-2 CHE(NCL):3-015: Chemistry and biology of Heterocycles: 2-0-0-2 CHE(NCL):3-023: Homogeneous Catalysis: 1-0-0-1 CHE(NCL):3-028: Materials and devices for energy conversion: 2-0-0-2 CHE(NCL):3-029: Functional Ceramics: 1-0-0-1 CHE(NCL):3-030: Modern Magnetic Materials: 1-0-0-1 CHE(NCL):3-031: Porous structures: 2-0-0-2 Final Draft

CHE(NCL):3-034: Electrochemical power sources: 2-0-0-2 CHE(NCL):3-035: Alternate energy materials: 2-0-0-2 CHE(NCL):3-037: Hydrogen generation and storage: 2-0-0-2 CHE(NCL):3-046: Polymers and Colloidal Solutions: 3-0-0-3 CHE(NCL):3-048: Controlled Radical/Living Polymerizations and Macromolecular Architectures: 2-0-0-2 CHE(NCL):3-051: X-Ray Diffraction and Structure of Solids: 3-0-0-3 CHE(NCL):3-052: NMR spectroscopy: 3-0-0-3 CHE(NCL):3-053: Mass spectrometry applications: 2-0-0-2 CHE(NCL):3-055: Small Angle Scattering Techniques: 3-0-0-3

400 level courses Compulsory courses CHE(NCL):4-001: Project proposal writing & presentation: 0-0-4-2 CHE(NCL):4-002: Project proposal writing & presentation: 0-0-4-2 CHE(NCL):4-003: CSIR-800: 0-0-8-4

Final Draft

National Institute for Interdisciplinary Science & Technology (NIIST) Thiruvananthapuram. Chemistry Courses. 1) 2) 3) 4) 5) 6)

CHE(NIIST)- 100 Level Courses

CHE(NIIST): 1-001: Research Methodology: 1-0-0-1 CHE(NIIST): 1-002: Analytical Tools and Instrumentation: 1-0-0-1 CHE(NIIST): 1-003: Basic Mathematics and Numerical Methods: 1-0-0-1 CHE(NIIST): 1- 004: Basic Chemistry for Interdisciplinary sciences: 1-0-0-1 CHE(NIIST): 1-005: Introduction to Nanoscience and Nanotechnology: 1-0-0-1 CHE(NIIST): 1-006: Introduction to Chemical Biology: 1-0-0-1 CHE(NIIST) -200 Level Courses

1) CHE(NIIST): 2-002: Advanced Inorganic Chemistry: 2-0-0-2 2) CHE(NIIST): 2-003: Advanced Organic Chemistry : 2-0-0-2 3) CHE(NIIST): 2-005 : Advanced Quantum Mechanics: 2-0-0-2 4) CHE(NIIST): 2-006 : Advanced Organometallic Chemistry: 2-0-0-2 5) CHE(NIIST): 2-007 : Advanced Co-ordination Chemistry : 2-0-0-2 6) CHE(NIIST): 2-008: Advanced Photochemistry : 2-0-0-2 7) CHE(NIIST): 2-009: Advanced Polymer Chemistry: 2-0-0-2 8) CHE(NIIST): 2-014: Advanced Material Science : 2-0-0-2 9) CHE(NIIST): 2-018: advanced Materials Characterization Techniques: 2-0-0-2 10) CHE(NIIST): 2-019 : Advances in Nanoscience nanotechnology : 2-0-0-2 11) CHE(NIIST): 2-023: Rare Earth Chemistry: 2-0-0-2 12) CHE(NIIST): 2 -024: Sol-Gel Chemistry :2-0-0-2 13) CHE(NIIST): 2-026: Green Chemistry Concepts: 1-0-0-1 14) CHE(NIIST): 2-029: Natural Products: 2-0-0-2 15) CHE(NIIST): 2- 031: Synthetic Methods for Organic Chemists: 2-0-0-2 16) CHE(NIIST): 2-032: Organic Reaction Mechanisms: 2-0-0-2 17) CHE(NIIST): 2-036: Composite Materials: 2-0-0-2 18) CHE(NIIST): 2-038: Organic Spectroscopy applications: 2-0-0-2 19) CHE(NIIST): 2-039: Surface Characterization Techniques: 2-0-0-2 CHE(NIIST)- 300 Level Courses 1) 2) 3) 4) 5) 6) 7) 8)

CHE(NIIST): 3- 003: Electronic structure Theory: 2-0-0-2 CHE(NIIST): 3-004: Molecular Modeling and simulation: 2-0-0-2 CHE(NIIST): 3- 008: Carbohydrate Chemistry: 2-0-0-2 CHE(NIIST): 3-012: Supramolecular Chemistry: 2-0-0-2 CHE(NIIST): 3-013: Total Synthesis : 1-0-0-1 CHE(NIIST): 3- 014: Asymmetric synthesis: 1-0-0-1 CHE(NIIST): 3- 015: Chemistry and Biology of heterocycles: 2-0-0-2 CHE(NIIST): 3- 023: Homogenous Catalysis: 1-0-0-1

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9) CHE(NIIST): 3-025 : Catalysis for Organic Synthesis: 1-0-0-1 10) CHE(NIIST): 3-028: Materials and Devices for energy conversion: 2-0-0-2 11) CHE(NIIST): 3- 029: Functional ceramics: 1-0-0-1 12) CHE(NIIST): 3-036: Photoinduced electron and Energy Transfer: 2-0-0-2 13) CHE(NIIST): 3- 042: Block Copolymers: 2-0-0-2 14) CHE(NIIST): 3-049: Pi-conjugated Polymers: 2-0-0-2 15) CHE(NIIST): 3- 050: Liquid Crystals: 2-0-0-2 16) CHE(NIIST): 3-054: Ultrafast processes and Spectroscopy: 2-0-0-2 17) CHE(NIIST): 3- 056: Natural Products and drug discovery: 2-0-0-2 18) CHE(NIIST): 3- 058: Photobiology: 2-0-0-2

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100 level courses 101 and 102/103 are compulsory CHE-LAB-1-101 Research Methodology: 1-0-0-1 Good laboratory practices, Safety in the laboratory, First Aid in the laboratory, Maintenance of laboratory records, Scientific literature management, Communication skills (scientific writing and presentation), Intellectual property management & planning, Ethics in Science, Computer applications and tools, Statistical methods & Data analysis CHE-LAB-1-102 Analytical Tools and Instrumentation: 1-0-0-1 Thermal methods (TG, DTG, DTA, TMA, DSC), X-ray methods (XRD, XRF, SAXS), NMR (1H, 13C) and other Spectroscopic methods (EPR, IR, UV, Fluorescence), Chromatographic methods (TLC, GC, LC), Mass spectroscopy, Electron Microscopy (SEM, TEM), Electron Probe Micro Analysis (EDS, WDS), Quantitative Analysis (AAS, ICP, CHN) CHE-LAB-1-103 Basic mathematics and numerical methods: 1-0-0-1 Determinants and Matrices, Complex Variables, Vector analysis, Infinite Series, Special Functions, Differential Equations, Interpolation and Approximation, Numerical differentiation and Integration, Basic Linux, Introduction to Algorithms, basic programming, Shell and Shell Scripting, Network Computing and Parallel Computing, Matlab/Scilab/Octave/Gnuplot CHE-LAB-1-104* (*Optional course) Basic Chemistry for Interdisciplinary sciences: 1-0-0-1 Basics of inorganic, organic, physical and biochemistry, Nomenclature (IUPAC), molarity, molality and normality, types of bonding, Ionic, covalent and non-bonding interactions, Acids and bases, Atomic structure, periodic table and periodic properties, stoichiometry, chemical reactions and kinetics, solvent effects, functional groups in organic compounds, general named reactions and reaction mechanisms, carbohydrates, lipids, proteins, nucleotides, enzymes, photosynthesis CHE-LAB-1-105* (*Optional course) Introduction to Nanoscience and Nanotechnology: 1-0-0-1 General considerations, Introduction, definitions, consequences of size reduction, Properties: structural, thermodynamic, optical, electrical and magnetic properties, Methods of synthesis, Surface modifications, factors governing the stability and assembly, Characterization of nanomaterials, Applications of Nanomaterials CHE-LAB-1-106* (*Optional course) Introduction to Chemical Biology: 1-0-0-1 chemical biology/synthetic biology, Structure, function and chemistry of biological macromolecules including amino acids, proteins, nucleic acids and carbohydrates, Chemical kinetics and thermodynamics in biology, Chemical reactions and chemical diversity in Biology The Chemistry of Enzymes, Lipids, Fats & Steroids, Drug discovery, Drugs from Nature, Drug interaction *Optional courses, over and above minimum requirements if required

Final Draft

200 level courses 201/202/203 compulsory (Core) CHE-LAB-2-201 Advanced Physical Chemistry: 2-0-0-2 Thermodynamics and chemical kinetics, Quantum Mechanics, Atomic structure and spectroscopy, Chemical bonding in diatomics, Chemical applications of group theory, Colloids and Surface science, surfactants, Interface and Interfacial properties, Electrochemistry. CHE-LAB-2-202 Advanced Inorganic Chemistry: 2-0-0-2 Structure & Bonding in Inorganic Compounds, Chemistry of Coordination Compounds, Symmetry in Chemistry & Group Theory, Main group chemistry, Organometallic chemistry, Electronic Spectra of Transition Metal Compounds, Magneto Chemistry, Metal Cluster Compounds, Inorganic Reaction Mechanism, Electron Transfer Reactions in Metal Complexes, Bioinorganic Chemistry (Metalloenzymes, Metal complexes as oxygen carriers, Photosynthesis), Metal Complexes in Medicinal Chemistry, Catalysis by Inorganic Complexes. CHE-LAB-2-203 Advanced Organic Chemistry: 2-0-0-2 Stereochemistry, reaction mechanism, C-C and C-X bond formations, Retrosynthetic analysis, photochemistry, pericyclic reactions, reactive intermediates, Methods of asymmetric synthesis and their application in total synthesis, oxidation-reduction reactions, organocatalysis, metathesis reactions. CHE-LAB-2-204 Advanced Analytical Chemistry: 2-0-0-2 Analytical instrumentation, signal and noise, Overview of optical methods of analysis: Components of optical instruments, atomic and molecular spectrometry based on absorption, emission and scattering, Electroanalytical techniques (basic electrochemistry, voltammetry, potentiometry), Analytical separations and introduction to chromatographic methods, GC, LC, Mass spectrometry, electromigration techniques, hyphenated techniques, detectors, Analytical tools for petroleum refining. CHE-LAB-2-205 Advanced Quantum Mechanics: 2-0-0-2 Revision of Hydrogen atom and particle in box (1D and 3D), Approximate methods in quantum mechanics; Non degenerate perturbation ; Perturbation treatment of the Helium atom ground state and first excited state; Variation method for helium atom ground state; Comparison of perturbation and variation method, Structure of many electron wave function, Antisymmetry, Valence bond theory for homo and hetero nuclear diatomic molecules; Molecular orbital theory Comparison of MO and VB theory; Introduction to density functional theory; Hartree Fock theory, Overview of methods beyond Hartree Fock theory; Configuration Interaction; Many body perturbation; Coupled cluster CHE-LAB-2-206 Advanced Organometallic Chemistry: 2-0-0-2 Fundamentals, The 18 Valence Electron Rule; Structure and bonding of organometallic complexes using molecular orbital theory. Final Draft

σ-Donor Ligands: Transition-Metal-Alkyl and -Aryl compounds; σ-Donor/π –Acceptor Ligands: Transition-Metal-Alkenyl, -Aryl and –Alkynyl Complexes, Transition-MetalCarbenes (Fischer and Schrock Carbenes); Metal Carbonyl; Structure, properties and principal reaction types of the above complexes; σ, π -Donor/π –Acceptor Ligands: Olefin Compleses; Alkyne, Allyl and Enyl Complexes, Complexes of the cyclic CnHn Fundamental Mechanism of Organometallic Transformations: Oxidative addition, Migratory Insertion, β-hydride elimination and reductive elimination; Interaction of C-C and C-H σbonds with Transition Metals CHE-LAB-2-207 Advanced Coordination Chemistry: 2-0-0-2 Naming of coordination compounds, classification of ligands, chelate and macrocyclic effect, Theories dealing with the formation of Coordination Compounds, Spectrochemical Series; Splitting of d-orbitals, Jahn–Teller Effect; Stability constants of Transition metal complexes and their determination by Job’s Method. Spin–Orbit Coupling, Electronic states and term symbols, Selection rules (Laporte and spin selection rule), Interpretation of electronic spectra of Transition metal complexes, Orgel and Tanabe Sugano diagrams. Charge Transfer spectra, Magnetic Properties of Transition elements, Chemistry of Inner Transition Elements. CHE-LAB-2-208 Advanced Photochemistry: 2-0-0-2 Introduction to photochemistry, excited state processes, fluorescence and phosphorescence, quantum yields, charge-transfer spectra, solvatochromism, photochromism, transient absorption techniques, Luminescence emission lifetimes, two- and multiphoton processes, photoinduced energy and electron transfer, FRET, fluorescence polarization, excimers, exciplexes, delayed fluorescence, Photochemistry of Organic chromophores. Photochemistry in organized and confined media. CHE-LAB-2-209 Advanced Polymer Chemistry: 2-0-0-2 Techniques of polymerization, polymer characterization techniques, Stereochemistry of Polymers, polymer nano-architectures, random and block copolymers, Liquid Crystalline Polymers, Conducting Polymers, Non-linear Polymers, Polymer Blends and Composites, polymer rheology, inorganic, bio and supramolecular polymers CHE-LAB-2-210 Advanced Electrochemistry: 2-0-0-2 Basic electrochemistry concepts, Reference electrodes, Electrochemical Thermodynamics, Kinetics of electron transfer, the Taft equation, Diffusion, Double Layers, electrode Kinetics, the Gibbs adsorption isotherm, the Lippmann equation, infinitely dilute solutions and thermal balance, Electro capillary phenomena, Faradaic vs. capacitive currents, transport properties, potential theory, Electrochemical Techniques, Voltammetry, Reversible and irreversible reactions, Mass transport by convection, rotating electrodes, Equivalent circuits, A.C. voltammetry, Electrolysis methods, Adsorption, Thin layer cells, Electrochemistry of polymers and inorganic solids, Spectroelectrochemistry, Applications. CHE-LAB-2-211 Advances in Bioinorganic chemistry: 2-0-0-2 Metal ions in biology, structure and function of metallo-proteins and enzymes, Communication role for metals in biology. Heme and non-heme systems with one-, two- or multi-metal, photosynthesis and photosystem II; O2-binding, reduction to O2-, O22-, and O2species their utilization in hydroxylation and epoxidation; nitrogen fixation, water-oxidation reactions. Synthetic models, Correlation with structure and function of the natural enzymes, Final Draft

design and synthesis, hydroporphyrins.

mechanisms.

Metal

based

drugs,

Porphyrins,

Corrins,

CHE-LAB-2-212 Advances in hydrocarbon chemistry: 2-0-0-2 Chemistry of crude oil, thermal cracking, visbreaking and coking processes, catalytic cracking, hydro cracking and hydrogen production processes, catalytic reforming process, Chemistry and industrial processes for alkylates, isomerisation processes, Petrochemicals, Basic Building blocks; C1-Chemistry; Petrochemicals from n-paraffins; Petrochemicals from olefins and aromatics; Refinery-Petrochemical Integration, Future Prospects CHE-LAB-2-213 Advanced process chemistry: 2-0-0-2 Integral and Differential analysis; Evaluation of rate equations, unit processes, mass transfer, mass balance, energy balance, fluid flow, Design of homogeneous systems, different types of reactors, green chemistry CHE-LAB-2-214 Advanced Materials Science: 2-0-0-2 Crystal systems and space groups, Close packing and various simple structure types like AB, AB2, AB3 and complex structural types ABX3, AB2X4, etc. Factors affecting crystal structures, Common preparative methods; X-ray diffraction and Electron microscopy, Defect structures, colour centers, reciprocal lattices, Properties of solids – Band theory, metals, insulators, semiconductors, dielectric and ferroelectric properties, magnetic properties, optical properties, ionic conduction; structure-processing-property correlations. CHE-LAB-2-215 Advanced Catalysis: 2-0-0-2 Homogeneous and heterogeneous catalysis, adsorption, diffusion, kinetics, equilibrium and rate expressions; chiral catalysis, Surface Science in Catalysis, Catalytic Materials; Supports; Active Components, Classes of reactions and types of reactors; Catalyst preparation methods; Characterization of catalysts; Catalysis in super critical media; Brief introduction of organo and electrocatalysis; Structure-activity-property-stability of catalysts, Catalysts in chemical industry, Catalysis in petroleum refining and petrochemicals; Catalysis in the utilization of renewable feed stocks and concepts of sustainable chemistry. CHE-LAB-2-216 Advanced Surface Science: 2-0-0-2 Introduction to Surface Science - Surface phenomena - Adsorption, Desorption, Adsorption Models, Special properties of surfaces and interfaces, Electronic structure of surfaces, Surface modification and its applications, Nanoscale catalysis and applications, Surface spectroscopy and microscopy tools for nanocatalysis CHE-LAB-2-217 Advanced Separation Science and Technology: 2-0-0-2 Resins and membranes for separations, Classification of membranes; electromembrane Processes; Ion-exchange membranes and their applications, Electrodialysis and related processes. Polymer electrolyte membrane and their applications for fuel cells; Water electrolyzer for hydrogen production; Reverse electrodialysis for non-renewable energy from concentration gradient, reverse osmosis, nanofiltration, ultrafiltartion, pervaporation and gas separation: Membrane fouling, concentration polarization and other limitations of Pressuredriven membrane technologies.

Final Draft

CHE-LAB-2-218 Advanced Materials Characterization Techniques: 2-0-0-2 Optical Microscopy, Electron microscopy: TEM, HRTEM, SEM, STEM, EDX, FIB, e-beam lithography, Scanning probe microscopy: AFM, STM, MFM, confocal, etc, Raman spectroscopy/microscopy, Thermal analysis techniques, Magnetic measurements, Electrical measurements, Spectroscopic ellipsometry. CHE-LAB-2-219 Advances in Nanoscience and Nanotechnology: 2-0-0-2 Low-dimensional structures: Quantum wells, Quantum wires, and Quantum dots, Nano clusters & Nano crystals, fullerenes, carbon nano tubes and graphene, Nano Composites, synthesis and characterization techniques, Properties at Nano Scales and comparison with bulk materials, fabrication techniques, general applications, nanomaterials in biology. CHE-LAB-2-220 Advances in soft matter chemistry: 2-0-0-2 Condensed Matter, Colloids, Characterization of colloids by light scattering and electric-field based techniques, Micelles, Self-assembled systems, Molecular gels, Lyotropic liquid crystalline phases, One-, Two- and Three-dimensionally ordered phases, Thermotropic Liquid crystals textures and their identification, characterization of mesophases, Description of order parameter, Phase transitions. CHE-LAB-2-221 Advances in Chemical Biology: 2-0-0-2 Amino Acids, Peptides & Proteins, Design of poly peptides, Peptide hormones and their pharmaceutical significance, Peptide mimetics as therapeutics, Chemistry of Carbohydrates, Nucleic acids, Structure & function of DNA and RNA, Nucleic acid mimetics & their therapeutic applications, Chemistry of Enzymes, Lipids, Fats & Steroids, Drug discovery , Basic principles of medicinal chemistry, Drugs from Nature, Natural products based drug discovery, Kinetics and thermodynamics of biological process, Enzyme Catalysis, consecutive, parallel and competitive reactions in biological systems, Thermodynamics, alosteric effect in biology, types of bonds, hydration and their specific contribution towards specific thermodynamic parameters, enthalpy or entropy, Scatchard analysis, hill plot analysis. CHE-LAB-2-222 Advanced Biomaterials: 2-0-0-2 Definition of biomaterials, Surface property requirements of biomaterials, Types of materials used in medicine, Synthesis and surface characterization, Biology of wound healing, foreign body response and tissue remodeling, Molecular and cellular interactions of materials with biological environment, Degradation and long term fate of materials used in medicine, Requirements of biomaterials for biomedical implants, surface coatings, wound dressings, sutures, cardiovascular devices, ophthalmology, dentistry, orthopedics and cosmetic surgeries, Applications in drug delivery and tissue engineering, Standard protocols for testing the efficacy and efficiency of biomaterials, The regulatory environment for biomaterials, Some concepts for design development of common biomaterials. CHE-LAB-2-223 Rare Earth Chemistry: 2-0-0-2 Lanthanides and actinides, Electronic structure, periodic properties, extraction, separation, solution chemistry, coordination compounds, spectroscopy, luminescence, magnetism, dyes and pigments, trans-uranium elements, nuclear technology, displays and energy related applications.

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CHE-LAB-2-224 Sol-gel chemistry: 2-0-0-2 Introduction, Hydrolysis and condensation reactions, Solution chemistry and physics of intermediates, Role of the anion on the hydrolysis and condensation reactions, Kinetics of Hydrolysis and Condensation, Non-Hydrolytic Sol-Gel Processing, Gelation, Ageing, Drying, Densification, Characterization, Chemistry of Sol-Gel Silicates, Solution chemistry of transition metal alkoxide precursors, Sol-gel synthesis and characterization of important materials, structure-property relationships CHE-LAB-2-225 Combinatorial chemistry: 1-0-0-1 Principles and techniques of combinatorial chemistry, Popular organic reactions in combinatorial chemistry. solid-phase organic synthesis, Solution-phase parallel synthesis, mixture-based compound libraries, principles of compound library design, natural product and natural product-like libraries, case studies of combinatorial chemistry in drug discovery CHE-LAB-2-226 Green chemistry: 1-0-0-1 Green chemistry concepts: Basic understanding, scope and interdisciplinary nature of green chemistry; Environmental factors; Carbon credit, Energy efficiency and atom economy, Catalysis and green chemistry, Alternate reaction media and reaction systems, ionic liquids, supercritical fluids, solventless chemistry. CHE-LAB-2-227 Coal chemistry: 2-0-0-2 Mining processes, mine safety, Sampling methods of coal and its importance, Coal classification systems, Physical characterization, proximate analysis, Ultimate analysis, Sulphur analysis, Ash fusion temperature, Low temperature Carbonization, Swell Index, Cracking Index , Thermogravimetric analysis etc, Size Reduction and Size Classification of Coal, Structure of coal, Organic functionality of coal, aromatic Index, Mineral matter content, Mineralogy of coal, Geological origin of coal, petrographic analysis, geochemical processes during mining of coals, Coal Utilization, Coal Conversion processes, Other useful products from coal, Environmental Issues, CO2 sequestration. CHE-LAB-2-228 Alternative feedstock options for petrochemicals: 2-0-0-2 Global scenario of Petrochemicals, Renewable resources; categorization of resources; chemicals from edible renewable resource; Chemicals from non-edible renewable resources; Catalytic reactions (mineral acid, bases; enzymes, homogeneous and heterogeneous catalysts); alternate fuels; fuels derived from renewable resources; biodiesel, bioethanol, biobutanol; Hydrogen generation from renewable feed stocks, Conversion of glycerol; Naphtha as a conventional source, Need for sustainability in production of Petrochemicals, Alternate Options; from Refineries sources, Natural Gas/Methane as an Option and other Non Refinery Sources, CO2 utilization, Identification and Recommendations based on techno-economic analysis for India. CHE-LAB-2-229 Natural products: 2-0-0-2 Carbohydrates and polysaccharides, Structure and functions of important derivatives of monosaccharides, Classification and nomenclature and synthesis of some simple Alkaloids; Terpenoids and Steroids such as pinene; Camphor and Cadenine; α-vetinone; Hirsutene and Abietic acid (Terpenoids); Cholesterol; Testosterone and Andestrone (Steroids) etc. isolation and characterization, elucidation of structure-property relationships. Biosynthesis of steroids, terpenoids, fatty acids, alkaloids and polysaccharides, biosynthesis of natural products Final Draft

CHE-LAB-2-230 Ionic liquids: 1-0-0-1 Introduction to ionic liquids, ionic liquids vs. molecular solvents/ionic salts (solids), ionic liquids vs. eutectic mixtures, solvent polarities using different spectral techniques (parameters), physicochemical properties of ionic liquids, effect of functional groups on the properties of ionic liquids, surface active ionic liquids, aggregation behavior of ionic liquids, interaction of ionic liquids with different molecular solvents, interaction of ionic liquids with biopolymers, thermodynamics of the binary mixtures of ionic liquids, structure property relationship in ionic liquids. CHE-LAB-2-231 Synthetic methods for organic chemists: 2-0-0-2 Formation of carbon-carbon bond employing various kinds of organometallic reagents, C-C double bonds through different reactions, oxidation, reduction through various kinds of reagents, functional group interconversion, by substitution including protection and deprotection, alkylation of enolates, and other carbon nucleophiles, reaction of carbon nucleophiles with carbonyl compounds, electrophilic addition to C-C multiple bonds, reactions of C-C multiple bonds, Retrosynthesis, disconnection, synthons, linear and convergent synthesis, umpolung of reactivity and protecting groups. CHE-LAB-2-232 Organic reaction mechanisms: 2-0-0-2 Basics, The concept of Aromaticity, How to write an organic reaction mechanism?, Popular name reactions, Reactive intermediates: Generation, stability, structures and reactivity of carbocation, carbaion, carbene, radicals, benzyne, nitrene, Types of mechanism: classification, limitations examples of aliphatic nucleophilic substitution - aliphatic electrophilic substitution - aromatic nucleophilic substitution - aromatic electrophilic Substitution - types of radical reactions - molecular rearrangements oxidation and reduction; Electrophilic reactions-Friedel crafts reaction, Riemer Tiemenn reaction, Beckmann rearrangements; nucleophilic reactions- aldol condensation, perkin reaction, benzoin condensation;free radical reaction-halogenation of alkane, addition of HBr on alkene in presence of peroxide;allylic halogenation - using N-Bromo Succinamide (NBS), thermal halogenation of alkene CH3 – CH = CH2 CHE-LAB-2-233 Dyes and pigments: 1-0-0-1 Colour and constitution, chromogen and chromophore. Classification of dyes based on structure and mode of dyeing, Chemistry of some important dyes, NIR reflecting dyes, Dyes for solar cells CHE-LAB-2-234 Physical organic chemistry: 2-0-0-2 Hammett concepts-Quantitative structure activity relationships, linear free energy relationships, Molecular mechanics, Semi-empirical and ab initio molecular theory, Pericyclic Reactions; Substituent Effects; Frontier Molecular Orbitals, HOMO-LUMO Interactions, Aromaticity, Odd and Even Alternant Hydrocarbons, Pericyclic Reactions The WoodwardHoffman Rules. Free Energy Changes, Transition State Theory, The Eyring Equation, The Mechanistic Significance of Kinetic versus Thermodynamic Control of Organic Reactions, The Hammond Postulate, The Curtin-Hammett Principle; Kinetic Isotope Effects, The Reactivity-Selectivity Principle, Substituent Effects, Absorption of Light by Organic Molecules, Jablonsky Diagrams, Morse Potential Energy Curves, Common Photochemical Reactions, Photocycloadditions.

Final Draft

CHE-LAB-2-235 Thermodynamics and Statistical Mechanics: 2-0-0-2 Introduction: Thermodynamics – A Macroscopic Theory of Matter; Laws of Thermodynamics, Ideal Gas Laws, Specific Heat Capacities; Concept of Free Energy, Hamiltonian Mechanics, Equilibrium Distributions and Ergodic Hypothesis, Ensembles, Thermodynamic Functions and the Distribution Function, g(r),Imperfect Gases, Kinetic Theory of Gases, Time Dependent Processes, Phase Transitions CHE-LAB-2-236 Composite materials: 2-0-0-2 Concept of Composite materials, Various types of composites, Classification based on Matrix Material: Organic Matrix composites, Polymer matrix composites (PMC), Carbon matrix Composites or Carbon-Carbon Composites, Metal matrix composites (MMC), Ceramic matrix composites (CMC); Classification based on reinforcements: Fiber Reinforced Composites, Fiber Reinforced Polymer (FRP) Composites, Laminar Composites, Particulate Composites, Reinforcements/Fibers ,Types of fibres, Multiphase fibers, Whiskers and Flakes, Mechanical properties of fibres, Processing of Advanced composites, Metal Matrix Composites: Casting – Solid State diffusion technique, Cladding – Hot isostatic pressing; Ceramic Matrix Composites: Liquid Metal Infiltration – Liquid phase sintering; Carbon – Carbon composites: Knitting, Braiding, Weaving; Polymer matrix composites: Preparation of Moulding compounds and prepregs – hand lay up method – Autoclave method – Filament winding method – Compression moulding – Reaction injection moulding, Processing and characteristics of nanocomposites, hybrid composites, functionally graded composites, smart and functional composites. CHE-LAB-2-237 Carbon allotropes: 1-0-0-1 Synthesis, characterization, structure, properties and applications of: Diamond, Graphite, Amorphous carbon, Charcoals, Fullerene and related compounds, Carbon nanotubes, Graphene. CHE-LAB-2-238 Organic spectroscopy applications: 2-0-0-2 Mass spectroscopy, IR spectroscopy, Proton magnetic resonance spectroscopy, Structural assignment by employing NMR techniques, Carbon-13 NMR spectroscopy, Introduction COSY, HSQC, HMBC, NOESY, ROESY, Structural elucidation using 2D-NMR methods CHE-LAB-2-239 Surface characterization techniques: 2-0-0-2 XPS, LEED, XAS, SEM, AFM, TEM, NSOM, SPR, SERS, static and dynamic contact angle measurements, Ellipsometry.

Final Draft

300 Level courses CHE-LAB-3-301 Mathematical Methods: 2-0-0-2 Determinants and Matrices : Orthogonal Matrices, Hermitian Matrices, Unitary Matrices, Dioganalisation of Matrices, Vector analysis : Scalar and Vector product, Triple scalar and vector product, Gradient, Divergence, Curl, Vector Integration, Gauss Theorem, Stokes Theorem. Vector Analysis in Curvilinear coordinates and Tensors, Infinite Series: Fundamental Concepts, Convergence tests, Taylors expansion, Power Series, Special Functions: Gamma Function, The Beta Function, Differential Equations: Series SolutionFrobnius Method, Bessel Functions, Legendre Functions, Hermite Functions, Laguerre Functions, Fourier Series, Applications of Fourier Series, Fourier Transforms CHE-LAB-3-302 Numerical Methods: 2-0-0-2 Fortran and Linux basics, Solution to the linear algebraic equations, Eigen Values problems, Interpolation and extrapolation, Random number and sorting, Minimization and maximization of functions, Modeling of data CHE-LAB-3-303 Electronic structure theory: 2-0-0-2 Post-Hartree-Fock methods: Moller-Plesset perturbation theory (MP2, MP3, and MP4), Configuration Interaction (CI), Coupled-Cluster single double (triple) (CCSD(T))– performance of various methods for the prediction of van der Waal and hydrogen bonding interactions, spectral properties. Density functional theory based methods: Hybrid and Minnesota functional – Application of DFT methods (excitation energy calculations). Density functional methods with Dispersion correction (Grimme’s approaches). Car-Parrinello Molecular Dynamics (CPMD) and Born-Oppenheimer Molecular Dynamics (BOMD). CHE-LAB-3-304 Molecular modeling and simulation: 2-0-0-2 Molecular Mechanics: Features of molecular mechanics - Force Fields: Bonds structure and bending angles, Electrostatic Vander Waals and non-bonded interactions, Hydrogen bonding - Derivatives of molecular mechanics energy function - Calculating thermodynamic properties - Force Field for inorganic systems - Energy minimization, Molecular Dynamics Simulation: Molecular Dynamics using simple models, Molecular Dynamics with continuous potentials, Solvent effects, Conformational changes, Thermostats, Barostas, Lincs and shake algorithms, Monte Carlo simulation Methods, sorption, Applications of Molecular Modeling CHE-LAB-3-305 Computer aided drug design: 2-0-0-2 Definition of a drug molecule and factor affecting their biological activity, definition of chemotherapeutic index, therapeutic index, design of a drug molecule and relationship of functional groups, discovery of new drugs: drug discovery without a lead, lead discovery, random screen, non-random screen, concept of absorption, distribution, metabolism, and excretion (ADME), drug receptors, physicochemical properties, mechanism of a drug action, stereochemistry and drug action, synthetic and natural drugs and their modifications to increase oral bioavailability, chirality and drug action, bioisosterism, drug receptorinteractions, topographical and stereo-chemical considerations, concept of drug resistance, drug synergism, enzyme inhibition and activation, molecular modeling and insilico drug design, concept of structure-activity relationship(SAR) and quantitative structure-activity Final Draft

relationship (QSAR), Lipinski rule of five, mechanism of action of some important drug molecules. CHE-LAB-3-306 Computational materials design: 2-0-0-2 Solids, Drude and Sommerfield theories of metals, Kronig-Penning model, Tight-Binding approximation, band structure, density of states, prediction of electrical and magnetic properties, Prediction of properties of organic molecules and polymers, Introduction to Multiscale Modeling and Simulations and applications. Monte Carlo simulation in various ensembles, Gas sensing properties of various porous materials using grand canonical Monte Carlo method, Dissipative particle dynamics, Mesoscale dynamics and applications. CHE-LAB-3-307 Multiphase reaction kinetics: 1-0-0-1 Mass transfer theories, Multi phase reactors, Multi phase reactors selection criteria; Mass transfer coupled with chemical reaction; measurement of gas-liquid parameters, Reaction in porous catalysts; effective diffusivity and structure of porous catalysts, Important design parameters for gas-liquid and solid reactors, Reactor modeling in petroleum refining industry, Modeling of catalytic sweetening, isomerisation, hydro treating, and FT synthesis. CHE-LAB-3-308 Carbohydrate chemistry: 2-0-0-2 Mono and disaccharides, polysaccharides, Bacterial polysaccharides, starch and cellulose, derivatives of cellulose, Protecting groups, Glycosylation reactions, Dynamics and interactions, carboxy methyl cellulose and gun cotton, structure, Conformational analyses, glycoconjugates, Immunology of carbohydrates. CHE-LAB-3-309 Biophysical chemistry: 2-0-0-2 Physico Chemical properties of Water, State of Water in biostructures & its significance, Lipids & Proteins, Membrane organization & stability, Protein lipid interactions, Phase properties of biological membranes, Transport across the membrane, Osmosis, molecular basis of aqueous channels, Structural level of proteins & stabilizing forces, Conformational anaysis of polypeptides, Ramachandran plot, Double helical structure of DNA, Conformational parameters of Nucleic acids & their constituents ,Types & structure of RNA, mRNA, rRNA, tRNA, Protein-ligand and DNA-protein interactions. CHE-LAB-3-310 Physics and chemistry of collagen: 2-0-0-2 Molecular Structure of Collagen, Native collagen fibrils, X-ray Diffraction studies of collagen, Electron mircroscopic appearance of collagen, synthetic collagen-like polypeptides, Chemistry of Collagen and its Distribution, Biosynthesis of Collagen, Crosslinking, Degradation, Isolation and Characterization of Collagen, Physico-Chemical Techniques for Collagenous Matrices, Microscopy and other Non-invasive methods. CHE-LAB-3-311 Marine Natural products: 2-0-0-2 Polysaccharide contents of various seaweeds, Phaeophyceae and Rhodophyceae, Bioactive compounds from halophytic plants and marine algae/seaweeds, Gelling polysaccharides, extraction from natural sources, characterization and properties. Preparation of polysaccharide based biodegradable materials, hybrid composites, stimuli responsive materials. Applications of polysaccharide based materials. Biosynthesis of bioactive polysaccharides, steroids, fatty acid derivatives and alkaloids.

Final Draft

CHE-LAB-3-312 Supramolecular chemistry : 2-0-0-2 Nature of supramolecular interactions, role of various non-covalent interactions, multiple hydrogen bonding motifs, Stability of H-bonds, Jorgensen model for H-bonding, supramolecular synthons , dimensions of supramolecular chemistry, Janus molecules. Photoresponsive molecules and self-assembly, Molecular recognition, classification of supramolecular host-guest complexes, supramolecular self-assembly, supramolecular polymers, molecular capsules, self- assembled dendrimers, self-assembled nanotubes, low molecular weight organogels. Characterization techniques of self-assemblies, supramolecular sensors. CHE-LAB-3-313 Total Synthesis: 1-0-0-1 Synthesis of complex organic molecules – planning and execution; Concepts of Retrosynthetic Analysis and Total synthesis of Natural products; Retrosynthesis; Disconnection; Synthons; Linear and Convergent Synthesis; Photochemistry in total synthesis; MCRs in total synthesis; Breakthrough synthesis – past and present. CHE-LAB-3-314 Asymmetric Syntheis: 1-0-0-1 Strategies for the preparation of optically pure compounds; Stereoselective, Enantioselective and Diastereoselective reactions; Stochiometric asymmetric synthesischiral auxiliaries, Evans Alsdol and modified versions; Catalytic asymmetric synthesis; Asymmetric Dihydroxylation; Asymmmetric Aminohydroxylation; Asymmetric Hydrogenation; Asymmetric allylation, propargylation, and alkylation; Chiral Organocatalysis; Cascade reactions by organocatalysis; Transition Metal based catalysis; Asymmetric amplification and autocatalysis. CHE-LAB-3-315 Chemistry and biology of Heterocycles: 2-0-0-2 Privileged heterocycles, Electronic properties, reactivity (electrophilicity and nucleophilicity), Synthetic methodologies, Biological properties of Natural products and drug candidates, Biosynthesis, Dimeric compounds and related stereochemistry CHE-LAB-3-316 Agrochemicals: 2-0-0-2 Biochemistry in agriculture, Carbohydrates, Proteins, Lipids, Vitamins and Minerals and Enzymes, Soil science, guidelines on agricultural crops micronutrients and fertilizers, Chemistry of pesticides, synthesis, formulations, mode of action, toxicology, resistance and residual analysis, Methodologies for the synthesis of agrochemicals and other relevant organic molecules, chemistry in Integrated Pest Management, Semiochemicals, insect growth regulators, botanical pesticides and other biotechnological approaches, Analysis of agrochemicals and residues - Botanical pesticides, hormones, pheromone, kairomones and plant volatiles CHE-LAB-3-317 Fluoro organic chemistry: 2-0-0-2 Importance of fluorine in organic compounds, Strategies to introduce fluorine/ trifluoromethyl group into organic molecules, Preparation of fluorinated reagents, Preparation of fluorinated carbon materials and their uses, Known fluorinated drugs and their mode of action, Overview on CFCs, HCFCs, HFCs, their preparation and applications, Halon susbsitutes, Harmful effects of fluorine and inorganic fluorides Final Draft

CHE-LAB-3-318 Corrosion science: 2-0-0-2 Basic aspects, Forms of corrosion, Atmospheric corrosion and protective coatings, Immersion corrosion and electrochemical protection, Corrosion monitoring, impedence spectroscopy, harmonics and NDT techniques. CHE-LAB-3-319 Nutraceuticals: 2-0-0-2 Raw material preparation, and characterization, extraction of valuable biomolecules, characterization of these molecules with stability study, preparation and formulations for functional foods. Characterization and stability study of neutraceuticals, properties and stability packaging of neutraceuticals. CHE-LAB-3-320 Salts from marine resources: 2-0-0-2 Physicochemical properties of NaCl crystals, Chemistry of salt manufacture, Influence of other dissolved salts in the salt purity, Survey of site for solar salt production, Scientific design and layout of solar salt works, Solar Salt manufacture, Mechanization of solar salt industries, Preparation of ultra pure salt through innovative methods, Fortification of salt with essential nutrients, Application of phase equilibrium for recovery of marine chemicals, Recovery of valuable marine chemicals from bittern, High purity magnesium chemicals from bittern CHE-LAB-3-321 Ionic liquids for lubricants: 1-0-0-1 Lubrication by Ionic liquids and its structural correlation, Ionic liquids interaction with surfaces, synthetic oil lubricants, synthesis of lubricating ionic liquids, effect of alkyl chain length and anions, IL lubrication oils at variable temperatures, thin films, heat capacity and thermal properties, viscosity and wetting properties, ionic liquids as additives for lubricants, comparison with conventional hydrocarbon oils, Case studies. CHE-LAB-3-322 Applications of ionic liquids: 1-0-0-1 Introduction to task specific ionic liquids, self-assembly of ionic liquids in aqueous/non aqueous media and synthesis of nanomaterials therein, ionic liquids in catalysis, extraction of metal ions, ionic liquids and biopolymers: dissolution, regeneration and ionic-gel formation, processing of lignocellulosic biomass using ionic liquids, clean separation of various fractions of biomass and recovery of valuable chemicals using ionic liquids, application of ionic liquids in electrochemistry, separation of azeotropic mixtures using ionic liquids, organic reactions in ionic liquids. CHE-LAB-3-323 Homogeneous Catalysis: 1-0-0-1 Organometallic Catalysis, Applications in organic synthesis: Olefin Isomerization, C-C Coupling reactions: Heck, Suzuki, Stille and Sonogashira reactions, Alkene and Alkyne Metathesis, C-Heteroatom coupling: Hydroamination, Olefin Oxidation, C-H activation, Oxidation reactions, hydrogenation of Alkenes, Industrial Applications. CHE-LAB-3-324 Catalysis in petroleum refining: 2-0-0-2 Deactivation in Catalysts and its Consequences, Regeneration and Rejuvenation in Catalysis, Industrial Catalytic Processes; Hydro cracking; Hydro treating; Reforming; Isomerization and Alkylation; Fluid Catalytic Cracking and Deep Catalytic Cracking, Catalysis for Clean Fuels; Gas to Liquid Technology; Catalysis for Hydrogen Production, Final Draft

Catalysis beyond Petroleum; Electro catalysis; Photo catalysis, Laboratory Training in Catalysis. CHE-LAB-3-325 Catalysis for organic synthesis: 1-0-0-1 A background on fine and specialty chemicals in chemical industry; Concept of atom economy; Homogeneous and heterogeneous catalytic reactions: hydrogenation, hydrogenolysis, dehydrogenation, selective oxidation, alkylation & acylation, isomerization and C-C bond forming reactions, Enzyme catalysis in organic synthesis; Reaction mechanisms CHE-LAB-3-326 Catalysis for biomass refining: 1-0-0-1 Classification of biomass; Catalytic processing of cellulosic and lignocellulosic materials for monomers or oligomers; Catalytic transformation biomass to fuels; Value addition of biomass/monomers to fine and specialty chemicals; Value addition of glycerol and their derivatives; Concept of bio-refinery – Role of catalysis CHE-LAB-3-327 Biocatalysis in petroleum refining: 1-0-0-1 Scope of Biocatalysis in Petroleum Refining, Thermophilic microorganisms and the thermozymes, Structure and function of proteins, Non-aqueous Biocatalysis, Protein Engineering and rate improvement, Enzyme kinetics and models, Challenges and opportunities on Bioprocess development on: Bio-desulphurization of crude oil and petroleum fractions; Bio-cracking and Bio-vis breaking; Bio-desulphurization of waste gases; Biocatalysts for renewable hydrocarbons and petrochemicals. CHE-LAB-3-328 Materials and devices for energy conversion: 2-0-0-2 Design of organic and Inorganic semiconductors, Approaches to process organic semiconductors by covalent and non covalent modifications, band edges and band gaps, Modulation of charge transport properties, kinetics of electron transfer, Design of small molecule dyes for DSSC, Electron transfer at interfaces, Transistors and solar cells, Fabrication of Devices, Device characterisation using dark current, IV curves under illumination, IPCE, Calculation of Voc, Jsc, Vpp, Ipp, FF and Pmax. hybrid solar cells CHE-LAB-3-329 Functional Ceramics: 1-0-0-1 Advanced Electronic Ceramics, high temperature ceramic super conductors, Dielectric ceramics, microwave ceramics, low k materials, SOFC materials, solid-ionic conductors, phosphor materials, Impedance analysis, varistors, sensors, ceramic magnets, thermal shock resistance and super plastic ceramics. CHE-LAB-3-330 Modern Magnetic Materials: 1-0-0-1 Types of magnetism, molecular field theory, measurement techniques, magnetoresistance (AMR, GMR, CMR, TMR), hard and soft magnets, New magnetic materials, applications. CHE-LAB-3-331 Porous structures: 2-0-0-2 Definitions, Micro-Porous and Mesoporous Solids, Structural Chemistry of Zeolite Framework Types, MOFs, COFs, Synthesis, Structure Determination, Role of the Structuredirecting Agents, The Chemistry of Microporous Framework Solids, Adsorption and Diffusion, Catalytic Applications, hydrogen storage, separation, CO2 sequestration, sensors, Final Draft

CHE-LAB-3-332 Biomaterials for targeted therapeutics : 2-0-0-2 Rational design and engineering of lipid-based targeted drug delivery vehicles and their therapeutic applications - Design of polymeric micelles as nano drug carriers - Design of polymer-based nanometric targeted delivery systems and their therapeutic applications Set-backs and unmet challenges – Cancer and its Hall Marks - Principles of designing anticancer therapeutics – Molecular basis of lung, breast, melanoma and prostate cancers – Rationale for selecting leading pathways in cancer therapy – Nuclear hormone receptors as targets in cancer therapy – Rationale for design of cancer therapy against multiple pathways – Concept of designing hybrid molecules as a dual strategy – Use of nanotechnology in cancer therapy – Concept of cancer stem cells and design of cancer stem cell therapeutics. CHE-LAB-3-333 Organic electrochemistry: 2-0-0-2 Cathodic reactions of organic compounds, Anodic reactions of organic compounds, Classifications of electrode reactions, Stereochemistry of electrochemical processes, Applications of organic electrochemistry. CHE-LAB-3-334 Electrochemical power sources: 2-0-0-2 Energy scenario, emissions and global warming, fuel cells, Thermodynamic potentials, electrochemical processes and electrode kinetics, Proton exchange membranes, proton conducting mechanisms, recent advances, Operating conditions, overview of characterization techniques, technical aspects, advantages, materials, significances and challenges, Materials for supercapacitor applications, recent advances in the system development, battery vs. supercapacitor, modern technologies, challenges and prospects. CHE-LAB-3-335 Alternate energy materials: 2-0-0-2 Energy scenario, Non-renewable and renewable energy sources; description of renewable sources and their importance. Technologies for biomass energy conversion, Solar energy, Wind Turbines, Geothermal Technologies; Applications; Sustainable sources of hydrogen; Fuel cell technologies; Hydrogen storage and distribution; Applications and feasibility assessment; Science, technology and policy of energy conservation; Strategies for enhancing role of renewable energy. CHE-LAB-3-336 Photoinduced electron and Energy transfer: 2-0-0-2 Thermodynamic aspects, Calculation of free energy change from redox potentials, Weller equation, Kinetic aspects, concept of reorganization energy, Marcus theory, Inverted region kinetics, Back electron transfer, circumventing back electron transfer, Applications of photoinduced electron and energy transfer, Reaction centre and photoinduced electron transfer processes in photosynthetic bacteria, Solar water splitting, Dye-sensitized solar cells, Organic photovoltaics, Few organic reactions initiated by PET, Photo-remediation of organic waste materials, Mechanisms and dynamics of fluorescence quenching, Fluorescence anisotropy, Energy transfer to single and multiple acceptors, Resonance energy transfer and its implication, Sensors based on photoinduced processes. CHE-LAB-3-337 Hydrogen generation and storage: 2-0-0-2 Sustainable sources of hydrogen; Fuel cell technologies; Hydrogen storage and distribution; Applications and feasibility assessment; Science, technology and policy of energy conservation; Strategies for enhancing role of renewable energy.

Final Draft

CHE-LAB-3-338 Thermochemical Conversion of Biomass: 1-0-0-1 Thermochemical conversion technologies for biomass pyrolysis, gasification, combustion, thermal and catalytic conversion of biomass; upgradation of pyrolysis products; bio-refining products and applications; biorefinery concept; Hybrid methods of conversion and effective utilization; Alternative and/or clean fuels, functional and bulk chemicals from biomass; life cycle analysis; carbon and water foot prints; Utilization of products and feasibility assessment; Science, technology and policy of biomass energy; Strategies for Enhancing role of renewable energy and Indian scenario. CHE-LAB-3-339 CO2 sequestration and conversion: 2-0-0-2 CO2 Sequestration; Capture techniques; overview of transportation and storage techniques, Basic properties of CO2, Reactivity of CO2, Utilization of CO2 as chemical feedstock, Utilization of CO2 as inert solvent for chemical synthesis, Coordination chemistry of CO2 and reactivity of coordinated CO2, Transition metal promoted reactions of CO2, The chemistry of N-CO2 bonds, Applications of CO2 for the synthesis of polymers, photochemical reduction of CO2, utilization of CO2 for the production of hydrocarbon fuels. CHE-LAB-3-340 Natural gas to liquid fuels: 2-0-0-2 generation processes; SMR; POx; ATR; DMR and Tri reforming, Syngas conversion processes; FT Synthesis, LTFT, HTFT, Low Pressure versus high pressure FT, Syn-crude up gradation by hydrocracking, methanol synthesis, chemistry of the processes; catalysts, development in reactors; tubular; multitubular; fixed bed; fluidized bed; FFB; CFB, SBCR, variables affecting SCBR, Commercial Processes; MTO; UOP/Hydro MTO; Exxon Mobil MTO; Lurgi MTP, DME Synthesis, status and prospects of DME production; Challenges for DME commercialization, commercialization activities of GTL plants, SSPD, SMDS, AGC- 21 and Gasel Processes. CHE-LAB-3-341 Gasoline reformulation techniques: 2-0-0-2 Environmental regulations on Fuel quality, Gasoline specifications and concept of reformulated gasoline, Gasoline production routes; Gasoline from Crude oil; General Properties of gasoline; Gasoline quality improvement drivers ; Chronological development in gasoline composition; Gasoline additives, Gasoline blending unit in a refinery; Dealing with aromatics, olefins and sulfur concentrations; Integration techniques to obtain reformulated gasoline, Refining processes; Reforming; Isomerisation, FCC Gasoline, Alkylation, Technologies for Alkylation. CHE-LAB-3-342 Block copolymers: 2-0-0-2 Chain and controlled block copolymerization, monomer reactivity ratios, Copolymer compositions, molecular architecture, blends, grafts, melts, self assembly and phase separation, phase diagram, range of applicability of copolymerization equation; types of copolymerization; Block copolymers with controlled molecular weight, Living Polymerization, block copolymer synthesis, characterization techniques, block copolymers for biomedical and industrial applications, Amphiphilic block copolymer micelles, Block copolymer thin films. CHE-LAB-3-343 Polymers for membrane applications: 2-0-0-2 Polymers as membrane materials, functional polymers containing styrene and its derivatives; Functionalized poly(arylene ether)s, Nafion and other Poly(perfluorosulfonic acid) Membranes, Post functionalized polymeric membranes, random and block copolymers; functional poly(imide)s; functional polyphosphazene; functionalized bioFinal Draft

polymers, design of new functional polymers; Glassy and rubbery polymers, characterization of polymer membranes, transport phenomena, polymer nanocomposites for membranes in the separation of gases and liquids, membrane fouling. CHE-LAB-3-344 Ion exchange polymers: 1-0-0-1 Adsorbents and ion exchange resins, Classification of ion exchange resins, Synthesis and characterization of ion-exchange resins and polymers, Water treatment and other applications, fouling, regeneration. CHE-LAB-3-345 Conducting polymers: 1-0-0-1 Synthesis and characterization, electrical transport properties, theory of conductivity, doping, electrochromic properties, Classification and types of organic conductors, Structure and properties of conducting charge-transfer salts, Conducting polymers based on organometallic compounds, Applications of conducting polymers, EMI shielding, supercapacitors, sensors CHE-LAB-3-346 Polymers and Colloidal Solutions: 2-0-0-2 Intermolecular forces and potentials, Overview of Statistical physics, DLVO theory, charged colloids, Poisson Boltzmann theory, Debye radius, Bjerrum length, electrophoresis, zeta potential, diffusion, Hydrodynamic interactions. Brief overview of Phase transitions in hard sphere colloids, Random walk, self avoiding random walk, flexible polymers, persistence length, Excluded volume interactions, Polymer solutions in the dilute limit/semi-dilute limit, Entropy of mixing, theta temperature, rubber elasticity, Polyelectrolytes, polymer at surfaces: Brushes, polymer dynamics. CHE-LAB-3-347 Biodegradable polymers: 2-0-0-2 Polymers from biomass, microbial production, synthetic polymers, structure and properties, Biodegradation mechanism, measurement techniques, processing techniques, sterilization and storage, global standards, market potential, applications. CHE-LAB-3-348 Controlled Radical/Living Polymerizations and Macromolecular Architectures: 2-0-0-2 Controlled or Living Radical Polymerization, TEMPO-mediated polymerization and atom Transfer radical Polymerization (ATRP), Kinetics of ATRP, Reversible Addition Chain Fragmentation Transfer (RAFT), Nitroxide mediated polymerization (NMP), Ring opening Metathesis polymerization (ROMP), living ROP, Macromolecular architectures using controlled living polymerizations CHE-LAB-3-349 Pi-conjugated polymers: 2-0-0-2 Synthesis and characterization, electronic and optical properties, energy band structure, Display Materials: Organic Light Emitting Diodes, Organic thin film transistors, device preparation, working principle, advantages, drawbacks; Organic photovoltaics, OFETs, device preparation and characterization, factors influencing efficiency, stability. CHE-LAB-3-350 Liquid Crystals: 2-0-0-2 Liquid crystal phases, classification, Chiral liquid crystalline phases, Ferroelectric liquid crystalline phases, discotic liquid crystalline phases, Characterization techniques, Surface Alignment of Liquid Crystals, Dichroic LCs, Polycatenar mesogenes, Display and photovoltaic applications. Final Draft

CHE-LAB-3-351 X-Ray Diffraction and Structure of Solids: 2-0-0-2 Introduction to X-ray crystallography,Crystal growth, evaluation and mounting, Symmetry and space group determination, Background theory for data collection, Data collection using four-circle diffractometers, Area detectors,Crystal lattices, Structure factors, Crystal symmetry, Structure solutions, Structure refinement, An introduction to maximum entropy, Least squares fitting of parameters, Practical aspects of structure refinement, Crystallographic Database, Structure solution from Powder Diffraction Data CHE-LAB-3-352 NMR spectroscopy: 2-0-0-2 Quantum Mechanics of NMR, Multinuclear NMR spectroscopy, Periodic table of NMR, Heteronuclear double resonance experiments, Magnetization transfer and signal enhancement, NMR of diamagnetic and paramagnetic compounds, Multidimensional NMR: 2D NMR, 1H-1H correlations, Heteronuclear Correlation Spectroscopy, 2D Exchange (EXSY), 2D NOESY, ROESY, DOSY Structure elucidation of small molecules, NMR of macromolecules, Multidimensional NMR Spectra, NMR Spectroscopy of Solids, 2D experiments in solids, semi rigid systems: HR MAS, Magnetic Resonance Imaging: In Vivo NMR, Imaging, MRI, functional MRI, NMR imaging of materials. CHE-LAB-3-353 Mass spectrometry applications: 2-0-0-2 Applications to analyze molecular, macromolecular and biological samples, Sample Preparation Protocols, Drug Metabolism and Pharmacokinetics (DMPK), Development of Quantitative analytical methods using mass spectrometry, Application to some model drugs, Metabolomics , Proteomics, GC-MS, LC-MS, MALDI-TOF, GC-TOF, TOF/TOF MS, LC-ESIMS, Protein Database search (MASCOT), Clinical Mass Spectrometry, CHE-LAB-3-354 Ultrafast processes and spectroscopy: 2-0-0-2 Different types of lasers, components and building of lasers and generation of ultrafast lasers. Principles, instrumentation and applications of different types of ultrafast spectroscopy, Conventional and laser flash Photolysis, and Pump-Probe spectroscopy, Steady state and time resolved Raman spectroscopy, Coherent anti-Stokes resonance Raman Spectroscopy, Femtosecond stimulated Raman Spectroscopy Femtosecond vibrational coherence spectroscopy, Transient grating Spectroscopy, Fluorescence upconversion, Time correlated single photon counting, ultrafast physical, chemical and biological systems. CHE-LAB-3-355 Small Angle Scattering Techniques: 2-0-0-2 SAXS and Fourier Transforms, General Theorems in Small Angle Scattering: Particulate systems: Porod and Guinier regimes, Pair density distribution functions, Single particle form factor for spheres, rods and plates, polydispersity, Structure factors for equilibrium concentrated particulate systems, measured structure factors for systems exhibiting polydispersity, Two phase systems: General Theorems, Detailed analysis of scattering from lamellar systems, relevance to semicrystalline polymers. CHE-LAB-3-356 Natural products and drug discovery: 2-0-0-2 Natural products: Importance, lead, clinical trials in drug discovery research, Case studies of marketed natural product drugs, Synthetic Biology and Genetic engineering in the production of natural product, A brief overview of drug discovery approach, Cause of diseases, Target identification, Target validation, Modeling, Synthesis and SAR, Drug Final Draft

Delivery, Clinical Trials, Etiology, pathogenesis, prevention, drug targets and chemotherapy, drug resistance and remedies of tropical infectious diseases, Etiology and remedies of diseases developed through metabolic disorders. CHE-LAB-3-357 Lipid science & technology: 2-0-0-2 Chemistry and Biochemistry of Lipids, Lipid Modification for Surfactant Preparation and Oleochemicals, Analytical Techniques for Lipids and Allied Products, Processing, Degumming, Bleaching, Dewaxing, Neutralization & Deodorization, Hydrogenation, Byproducts of lipids and their Value Addition, CHE-LAB-3-358 Photobiology: 2-0-0-2 Primary processes in photosynthesis, antenna effect, reaction center, primary processes in vision, bio and chemiluminescence and environmental photobiology and UV effects, Phototherapy and photodynamic therapy, sensitizers, structures of porphyrinic and nonporphyrinic sensitizers, type I and type II mechanisms, advantages and disadvantages of light in medicine. CHE-LAB-3-359 Nanobiotechnology: 1-0-0-1 Concept of hybrid systems, signaling and signaling responses; biological systems as transducers, Biology at the nano-interface, fluorescent nanoparticles for life sciences, applications, DNA based particles used as building blocks, micelles, Nucleic Acid Engineering using DNA as Nano materials, Cells & Microfabricated Devices, Nanomaterials for drug delivery, imaging, diagnostics, therapy, separation, Biosensors

Final Draft

400 level courses Compulsory courses CHE-LAB-4-401 Project proposal writing & presentation: 0-0-4-2 CHE-LAB-4-402 Project proposal writing & presentation: 0-0-4-2 CHE-LAB-4-403 CSIR-800: 0-0-8-4

Final Draft

CSIR-Indian Institute of Petroleum 100 level courses CHE-IIP-1-001 Research Methodology: 1-0-0-1 Good laboratory practices, Safety in the laboratory, First Aid in the laboratory, Maintenance of laboratory records, Scientific literature management, Communication skills (scientific writing and presentation), Intellectual property management & planning, Ethics in Science, Computer applications and tools, Statistical methods & Data analysis CHE-IIP-1-002 Analytical Tools and Instrumentation: 1-0-0-1 Thermal methods (TG, DTG, DTA, TMA, DSC), X-ray methods (XRD, XRF, SAXS), NMR (1H, 13C) and other Spectroscopic methods (EPR, IR, UV, Fluorescence), Chromatographic methods (TLC, GC, LC), Mass spectroscopy, Electron Microscopy (SEM, TEM), Electron Probe Micro Analysis (EDS, WDS), Quantitative Analysis (AAS, ICP, CHN)

Final Draft

200 level courses CHE-IIP-2-003 Advanced Organic Chemistry: 2-0-0-2 Stereochemistry, reaction mechanism, C-C and C-X bond formations, Retrosynthetic analysis, photochemistry, pericyclic reactions, reactive intermediates, Methods of asymmetric synthesis and their application in total synthesis, oxidation-reduction reactions, organocatalysis, metathesis reactions. CHE-IIP-2-004 Advanced Analytical Chemistry: 2-0-0-2 Analytical instrumentation, signal and noise, Overview of optical methods of analysis: Components of optical instruments, atomic and molecular spectrometry based on absorption, emission and scattering, Electroanalytical techniques (basic electrochemistry, voltammetry, potentiometry), Analytical separations and introduction to chromatographic methods, GC, LC, Mass spectrometry, electromigration techniques, hyphenated techniques, detectors, Analytical tools for petroleum refining. CHE-IIP-2-012 Advances in hydrocarbon chemistry: 2-0-0-2 Chemistry of crude oil, thermal cracking, visbreaking and coking processes, catalytic cracking, hydro cracking and hydrogen production processes, catalytic reforming process, Chemistry and industrial processes for alkylates, isomerisation processes, Petrochemicals, Basic Building blocks; C1-Chemistry; Petrochemicals from n-paraffins; Petrochemicals from olefins and aromatics; Refinery-Petrochemical Integration, Future Prospects CHE-IIP-2-015 Advanced Catalysis: 2-0-0-2 Homogeneous and heterogeneous catalysis, adsorption, diffusion, kinetics, equilibrium and rate expressions; chiral catalysis, Surface Science in Catalysis, Catalytic Materials; Supports; Active Components, Classes of reactions and types of reactors; Catalyst preparation methods; Characterization of catalysts; Catalysis in super critical media; Brief introduction of organo and electrocatalysis; Structure-activity-property-stability of catalysts, Catalysts in chemical industry, Catalysis in petroleum refining and petrochemicals; Catalysis in the utilization of renewable feed stocks and concepts of sustainable chemistry. CHE-IIP-2-028 Alternative feedstock options for petrochemicals: 2-0-0-2 Global scenario of Petrochemicals, Renewable resources; categorization of resources; chemicals from edible renewable resource; Chemicals from non-edible renewable resources; Catalytic reactions (mineral acid, bases; enzymes, homogeneous and heterogeneous catalysts); alternate fuels; fuels derived from renewable resources; biodiesel, bioethanol, biobutanol; Hydrogen generation from renewable feed stocks, Conversion of glycerol; Naphtha as a conventional source, Need for sustainability in production of Petrochemicals, Alternate Options; from Refineries sources, Natural Gas/Methane as an Option and other Non Refinery Sources, CO2 utilization, Identification and Recommendations based on techno-economic analysis for India.

Final Draft

300 Level courses CHE-IIP-3-007 Multiphase reaction kinetics: 1-0-0-1 Mass transfer theories, Multi phase reactors, Multi phase reactors selection criteria; Mass transfer coupled with chemical reaction; measurement of gas-liquid parameters, Reaction in porous catalysts; effective diffusivity and structure of porous catalysts, Important design parameters for gas-liquid and solid reactors, Reactor modeling in petroleum refining industry, Modeling of catalytic sweetening, isomerisation, hydro treating, and FT synthesis. CHE-IIP-3-021 Ionic liquids for lubricants: 1-0-0-1 Lubrication by Ionic liquids and its structural correlation, Ionic liquids interaction with surfaces, synthetic oil lubricants, synthesis of lubricating ionic liquids, effect of alkyl chain length and anions, IL lubrication oils at variable temperatures, thin films, heat capacity and thermal properties, viscosity and wetting properties, ionic liquids as additives for lubricants, comparison with conventional hydrocarbon oils, Case studies. CHE-IIP-3-024 Catalysis in petroleum refining: 2-0-0-2 Deactivation in Catalysts and its Consequences, Regeneration and Rejuvenation in Catalysis, Industrial Catalytic Processes; Hydro cracking; Hydro treating; Reforming; Isomerization and Alkylation; Fluid Catalytic Cracking and Deep Catalytic Cracking, Catalysis for Clean Fuels; Gas to Liquid Technology; Catalysis for Hydrogen Production, Catalysis beyond Petroleum; Electro catalysis; Photo catalysis, Laboratory Training in Catalysis. CHE-IIP-3-027 Biocatalysis in petroleum refining: 1-0-0-1 Scope of Biocatalysis in Petroleum Refining, Thermophilic microorganisms and the thermozymes, Structure and function of proteins, Non-aqueous Biocatalysis, Protein Engineering and rate improvement, Enzyme kinetics and models, Challenges and opportunities on Bioprocess development on: Bio-desulphurization of crude oil and petroleum fractions; Bio-cracking and Bio-vis breaking; Bio-desulphurization of waste gases; Biocatalysts for renewable hydrocarbons and petrochemicals. CHE-IIP-3-038 Thermochemical Conversion of Biomass: 1-0-0-1 Thermochemical conversion technologies for biomass pyrolysis, gasification, combustion, thermal and catalytic conversion of biomass; upgradation of pyrolysis products; bio-refining products and applications; biorefinery concept; Hybrid methods of conversion and effective utilization; Alternative and/or clean fuels, functional and bulk chemicals from biomass; life cycle analysis; carbon and water foot prints; Utilization of products and feasibility assessment; Science, technology and policy of biomass energy; Strategies for Enhancing role of renewable energy and Indian scenario.

Final Draft

CHE-IIP-3-039 CO2 sequestration and conversion: 2-0-0-2 CO2 Sequestration; Capture techniques; overview of transportation and storage techniques, Basic properties of CO2, Reactivity of CO2, Utilization of CO2 as chemical feedstock, Utilization of CO2 as inert solvent for chemical synthesis, Coordination chemistry of CO2 and reactivity of coordinated CO2, Transition metal promoted reactions of CO2, The chemistry of N-CO2 bonds, Applications of CO2 for the synthesis of polymers, photochemical reduction of CO2, utilization of CO2 for the production of hydrocarbon fuels. CHE-IIP-3-040 Natural gas to Liquid fuels: 2-0-0-2 generation processes; SMR; POx; ATR; DMR and Tri reforming, Syngas conversion processes; FT Synthesis, LTFT, HTFT, Low Pressure versus high pressure FT, Syn-crude up gradation by hydrocracking, methanol synthesis, chemistry of the processes; catalysts, development in reactors; tubular; multitubular; fixed bed; fluidized bed; FFB; CFB, SBCR, variables affecting SCBR, Commercial Processes; MTO; UOP/Hydro MTO; Exxon Mobil MTO; Lurgi MTP, DME Synthesis, status and prospects of DME production; Challenges for DME commercialization, commercialization activities of GTL plants, SSPD, SMDS, AGC- 21 and Gasel Processes. CHE-IIP-3-041 Gasoline reformulation techniques: 2-0-0-2 Environmental regulations on Fuel quality, Gasoline specifications and concept of reformulated gasoline, Gasoline production routes; Gasoline from Crude oil; General Properties of gasoline; Gasoline quality improvement drivers ; Chronological development in gasoline composition; Gasoline additives, Gasoline blending unit in a refinery; Dealing with aromatics, olefins and sulfur concentrations; Integration techniques to obtain reformulated gasoline, Refining processes; Reforming; Isomerisation, FCC Gasoline, Alkylation, Technologies for Alkylation.

Final Draft

400 level courses Compulsory courses CHE-IIP-4-001 Project proposal writing & presentation: 0-0-4-2 CHE-IIP-4-002 Project proposal writing & presentation: 0-0-4-2 CHE-IIP-4-003 CSIR-800: 0-0-8-4

Final Draft

CSIR-National Chemical Laboratory 100 level courses 001 and 002/003 are compulsory CHE(NCL):1-001: Research Methodology: 1-0-0-1 Good laboratory practices, Safety in the laboratory, First Aid in the laboratory, Maintenance of laboratory records, Scientific literature management, Communication skills (scientific writing and presentation), Intellectual property management & planning, Ethics in Science, Computer applications and tools, Statistical methods & Data analysis CHE(NCL):1-002: Analytical Tools and Instrumentation: 1-0-0-1 Thermal methods (TG, DTG, DTA, TMA, DSC), X-ray methods (XRD, XRF, SAXS), NMR (1H, 13C) and other Spectroscopic methods (EPR, IR, UV, Fluorescence), Chromatographic methods (TLC, GC, LC), Mass spectroscopy, Electron Microscopy (SEM, TEM), Electron Probe Micro Analysis (EDS, WDS), Quantitative Analysis (AAS, ICP, CHN) CHE(NCL):1-003: Basic mathematics and numerical methods: 1-0-0-1 Determinants and Matrices, Complex Variables, Vector analysis, Infinite Series, Special Functions, Differential Equations, Interpolation and Approximation, Numerical differentiation and Integration, Basic Linux, Introduction to Algorithms, basic programming, Shell and Shell Scripting, Network Computing and Parallel Computing, Matlab/Scilab/Octave/Gnuplot CHE(NCL):1-004: Basic Chemistry for Interdisciplinary sciences: 1-0-0-1 Basics of inorganic, organic, physical and biochemistry, Nomenclature (IUPAC), molarity, molality and normality, types of bonding, Ionic, covalent and non-bonding interactions, Acids and bases, Atomic structure, periodic table and periodic properties, stoichiometry, chemical reactions and kinetics, solvent effects, functional groups in organic compounds, general named reactions and reaction mechanisms, carbohydrates, lipids, proteins, nucleotides, enzymes, photosynthesis CHE(NCL):1-005: Introduction to Nanoscience and Nanotechnology: 1-0-0-1 General considerations, Introduction, definitions, consequences of size reduction, Properties: structural, thermodynamic, optical, electrical and magnetic properties, Methods of synthesis, Surface modifications, factors governing the stability and assembly, Characterization of nanomaterials, Applications of Nanomaterials CHE(NCL):1-006: Introduction to Chemical Biology: 1-0-0-1 chemical biology/synthetic biology, Structure, function and chemistry of biological macromolecules including amino acids, proteins, nucleic acids and carbohydrates, Chemical kinetics and thermodynamics in biology, Chemical reactions and chemical diversity in Biology The Chemistry of Enzymes, Lipids, Fats & Steroids, Drug discovery, Drugs from Nature, Drug interaction

Final Draft

200 level courses 001/002/003 compulsory (Core) CHE(NCL):2-001: Advanced Physical Chemistry: 2-0-0-2 Thermodynamics and chemical kinetics, Quantum Mechanics, Atomic structure and spectroscopy, Chemical bonding in diatomics, Chemical applications of group theory, Colloids and Surface science, surfactants, Interface and Interfacial properties, Electrochemistry. CHE(NCL):2-002: Advanced Inorganic Chemistry: 2-0-0-2 Structure & Bonding in Inorganic Compounds, Chemistry of Coordination Compounds, Symmetry in Chemistry & Group Theory, Main group chemistry, Organometallic chemistry, Electronic Spectra of Transition Metal Compounds, Magneto Chemistry, Metal Cluster Compounds, Inorganic Reaction Mechanism, Electron Transfer Reactions in Metal Complexes, Bioinorganic Chemistry (Metalloenzymes, Metal complexes as oxygen carriers, Photosynthesis), Metal Complexes in Medicinal Chemistry, Catalysis by Inorganic Complexes. CHE(NCL):2-003: Advanced Organic Chemistry: 2-0-0-2 Stereochemistry, reaction mechanism, C-C and C-X bond formations, Retrosynthetic analysis, photochemistry, pericyclic reactions, reactive intermediates, Methods of asymmetric synthesis and their application in total synthesis, oxidation-reduction reactions, organocatalysis, metathesis reactions. CHE(NCL):2-004: Advanced Analytical Chemistry: 2-0-0-2 Analytical instrumentation, signal and noise, Overview of optical methods of analysis: Components of optical instruments, atomic and molecular spectrometry based on absorption, emission and scattering, Electroanalytical techniques (basic electrochemistry, voltammetry, potentiometry), Analytical separations and introduction to chromatographic methods, GC, LC, Mass spectrometry, electromigration techniques, hyphenated techniques, detectors, Analytical tools for petroleum refining. CHE(NCL):2-005: Advanced Quantum Mechanics: 2-0-0-2 Revision of Hydrogen atom and particle in box (1D and 3D), Approximate methods in quantum mechanics; Non degenerate perturbation ; Perturbation treatment of the Helium atom ground state and first excited state; Variation method for helium atom ground state; Comparison of perturbation and variation method, Structure of many electron wave function, Antisymmetry, Valence bond theory for homo and hetero nuclear diatomic molecules; Molecular orbital theory Comparison of MO and VB theory; Introduction to density functional theory; Hartree Fock theory, Overview of methods beyond Hartree Fock theory; Configuration Interaction; Many body perturbation; Coupled cluster CHE(NCL):2-006: Advanced Organometallic Chemistry: 2-0-0-2 Fundamentals, The 18 Valence Electron Rule; Structure and bonding of organometallic complexes using molecular orbital theory. σ-Donor Ligands: Transition-Metal-Alkyl and -Aryl compounds; σ-Donor/π –Acceptor Ligands: Transition-Metal-Alkenyl, -Aryl and –Alkynyl Complexes, Transition-MetalCarbenes (Fischer and Schrock Carbenes); Metal Carbonyl; Structure, properties and principal reaction types of the above complexes; σ, π -Donor/π –Acceptor Ligands: Olefin Compleses; Alkyne, Allyl and Enyl Complexes, Complexes of the cyclic CnHn

Final Draft

Fundamental Mechanism of Organometallic Transformations: Oxidative addition, Migratory Insertion, β-hydride elimination and reductive elimination; Interaction of C-C and C-H σbonds with Transition Metals CHE(NCL):2-008: Advanced Photochemistry: 2-0-0-2 Introduction to photochemistry, excited state processes, fluorescence and phosphorescence, quantum yields, charge-transfer spectra, solvatochromism, photochromism, transient absorption techniques, Luminescence emission lifetimes, two- and multiphoton processes, photoinduced energy and electron transfer, FRET, fluorescence polarization, excimers, exciplexes, delayed fluorescence, Photochemistry of Organic chromophores. Photochemistry in organized and confined media. CHE(NCL):2-009: Advanced Polymer Chemistry: 2-0-0-2 Techniques of polymerization, polymer characterization techniques, Stereochemistry of Polymers, polymer nano-architectures, random and block copolymers, Liquid Crystalline Polymers, Conducting Polymers, Non-linear Polymers, Polymer Blends and Composites, polymer rheology, inorganic, bio and supramolecular polymers CHE(NCL):2-010: Advanced Electrochemistry: 2-0-0-2 Basic electrochemistry concepts, Reference electrodes, Electrochemical Thermodynamics, Kinetics of electron transfer, the Taft equation, Diffusion, Double Layers, electrode Kinetics, the Gibbs adsorption isotherm, the Lippmann equation, infinitely dilute solutions and thermal balance, Electro capillary phenomena, Faradaic vs. capacitive currents, transport properties, potential theory, Electrochemical Techniques, Voltammetry, Reversible and irreversible reactions, Mass transport by convection, rotating electrodes, Equivalent circuits, A.C. voltammetry, Electrolysis methods, Adsorption, Thin layer cells, Electrochemistry of polymers and inorganic solids, Spectroelectrochemistry, Applications. CHE(NCL):2-014: Advanced Materials Science: 2-0-0-2 Crystal systems and space groups, Close packing and various simple structure types like AB, AB2, AB3 and complex structural types ABX3, AB2X4, etc. Factors affecting crystal structures, Common preparative methods; X-ray diffraction and Electron microscopy, Defect structures, colour centers, reciprocal lattices, Properties of solids – Band theory, metals, insulators, semiconductors, dielectric and ferroelectric properties, magnetic properties, optical properties, ionic conduction; structure-processing-property correlations. CHE(NCL):2-015: Advanced Catalysis: 2-0-0-2 Homogeneous and heterogeneous catalysis, adsorption, diffusion, kinetics, equilibrium and rate expressions; chiral catalysis, Surface Science in Catalysis, Catalytic Materials; Supports; Active Components, Classes of reactions and types of reactors; Catalyst preparation methods; Characterization of catalysts; Catalysis in super critical media; Brief introduction of organo and electrocatalysis; Structure-activity-property-stability of catalysts, Catalysts in chemical industry, Catalysis in petroleum refining and petrochemicals; Catalysis in the utilization of renewable feed stocks and concepts of sustainable chemistry. CHE(NCL):2-016: Advanced Surface Science: 2-0-0-2 Introduction to Surface Science - Surface phenomena - Adsorption, Desorption, Adsorption Models, Special properties of surfaces and interfaces, Electronic structure of surfaces, Surface modification and its applications, Nanoscale catalysis and applications, Surface spectroscopy and microscopy tools for nanocatalysis CHE(NCL):2-017: Advanced Separation Science and Technology: 2-0-0-2 Resins and membranes for separations, Classification of membranes; electromembrane Processes; Ion-exchange membranes and their applications, Electrodialysis and related Final Draft

processes. Polymer electrolyte membrane and their applications for fuel cells; Water electrolyzer for hydrogen production; Reverse electrodialysis for non-renewable energy from concentration gradient, reverse osmosis, nanofiltration, ultrafiltartion, pervaporation and gas separation: Membrane fouling, concentration polarization and other limitations of Pressuredriven membrane technologies. CHE(NCL):2-018: Advanced Materials Characterization Techniques: 2-0-0-2 Optical Microscopy, Electron microscopy: TEM, HRTEM, SEM, STEM, EDX, FIB, e-beam lithography, Scanning probe microscopy: AFM, STM, MFM, confocal, etc, Raman spectroscopy/microscopy, Thermal analysis techniques, Magnetic measurements, Electrical measurements, Spectroscopic ellipsometry. CHE(NCL):2-019: Advances in Nanoscience and Nanotechnology: 2-0-0-2 Low-dimensional structures: Quantum wells, Quantum wires, and Quantum dots, Nano clusters & Nano crystals, fullerenes, carbon nano tubes and graphene, Nano Composites, synthesis and characterization techniques, Properties at Nano Scales and comparison with bulk materials, fabrication techniques, general applications, nanomaterials in biology. CHE(NCL):2-021: Advances in Chemical Biology: 2-0-0-2 Amino Acids, Peptides & Proteins, Design of poly peptides, Peptide hormones and their pharmaceutical significance, Peptide mimetics as therapeutics, Chemistry of Carbohydrates, Nucleic acids, Structure & function of DNA and RNA, Nucleic acid mimetics & their therapeutic applications, Chemistry of Enzymes, Lipids, Fats & Steroids, Drug discovery , Basic principles of medicinal chemistry, Drugs from Nature, Natural products based drug discovery, Kinetics and thermodynamics of biological process, Enzyme Catalysis, consecutive, parallel and competitive reactions in biological systems, Thermodynamics, alosteric effect in biology, types of bonds, hydration and their specific contribution towards specific thermodynamic parameters, enthalpy or entropy, Scatchard analysis, hill plot analysis. CHE(NCL):2-022: Advanced Biomaterials: 2-0-0-2 Definition of biomaterials, Surface property requirements of biomaterials, Types of materials used in medicine, Synthesis and surface characterization, Biology of wound healing, foreign body response and tissue remodeling, Molecular and cellular interactions of materials with biological environment, Degradation and long term fate of materials used in medicine, Requirements of biomaterials for biomedical implants, surface coatings, wound dressings, sutures, cardiovascular devices, ophthalmology, dentistry, orthopedics and cosmetic surgeries, Applications in drug delivery and tissue engineering, Standard protocols for testing the efficacy and efficiency of biomaterials, The regulatory environment for biomaterials, Some concepts for design development of common biomaterials. CHE(NCL):2-026: Green chemistry: 1-0-0-1 Green chemistry concepts: Basic understanding, scope and interdisciplinary nature of green chemistry; Environmental factors; Carbon credit, Energy efficiency and atom economy, Catalysis and green chemistry, Alternate reaction media and reaction systems, ionic liquids, supercritical fluids, solventless chemistry. CHE(NCL):2-032: Organic reaction mechanisms: 2-0-0-2 Basics, The concept of Aromaticity, How to write an organic reaction mechanism?, Popular name reactions, Reactive intermediates: Generation, stability, structures and reactivity of carbocation, carbaion, carbene, radicals, benzyne, nitrene, Types of mechanism: classification, limitations examples of aliphatic nucleophilic substitution - aliphatic electrophilic substitution - aromatic nucleophilic substitution - aromatic electrophilic Substitution - types of radical reactions - molecular rearrangements oxidation and reduction; Electrophilic reactions-Friedel crafts reaction, Riemer Tiemenn reaction, Beckmann Final Draft

rearrangements; nucleophilic reactions- aldol condensation, perkin reaction, benzoin condensation;free radical reaction-halogenation of alkane, addition of HBr on alkene in presence of peroxide;allylic halogenation - using N-Bromo Succinamide (NBS), thermal halogenation of alkene CH3 – CH = CH2 CHE(NCL):2-035: Thermodynamics and Statistical Mechanics: 2-0-0-2 Introduction: Thermodynamics – A Macroscopic Theory of Matter; Laws of Thermodynamics, Ideal Gas Laws, Specific Heat Capacities; Concept of Free Energy, Hamiltonian Mechanics, Equilibrium Distributions and Ergodic Hypothesis, Ensembles, Thermodynamic Functions and the Distribution Function, g(r),Imperfect Gases, Kinetic Theory of Gases, Time Dependent Processes, Phase Transitions CHE(NCL):2-036: Composite materials: 2-0-0-2 Concept of Composite materials, Various types of composites, Classification based on Matrix Material: Organic Matrix composites, Polymer matrix composites (PMC), Carbon matrix Composites or Carbon-Carbon Composites, Metal matrix composites (MMC), Ceramic matrix composites (CMC); Classification based on reinforcements: Fiber Reinforced Composites, Fiber Reinforced Polymer (FRP) Composites, Laminar Composites, Particulate Composites, Reinforcements/Fibers ,Types of fibres, Multiphase fibers, Whiskers and Flakes, Mechanical properties of fibres, Processing of Advanced composites, Metal Matrix Composites: Casting – Solid State diffusion technique, Cladding – Hot isostatic pressing; Ceramic Matrix Composites: Liquid Metal Infiltration – Liquid phase sintering; Carbon – Carbon composites: Knitting, Braiding, Weaving; Polymer matrix composites: Preparation of Moulding compounds and prepregs – hand lay up method – Autoclave method – Filament winding method – Compression moulding – Reaction injection moulding, Processing and characteristics of nanocomposites, hybrid composites, functionally graded composites, smart and functional composites. CHE(NCL):2-037: Carbon allotropes: 1-0-0-1 Synthesis, characterization, structure, properties and applications of: Diamond, Graphite, Amorphous carbon, Charcoals, Fullerene and related compounds, Carbon nanotubes, Graphene. CHE(NCL):2-038: Organic spectroscopy applications: 2-0-0-2 Mass spectroscopy, IR spectroscopy, Proton magnetic resonance spectroscopy, Structural assignment by employing NMR techniques, Carbon-13 NMR spectroscopy, Introduction COSY, HSQC, HMBC, NOESY, ROESY, Structural elucidation using 2D-NMR methods CHE(NCL):2-039: Surface characterization techniques: 2-0-0-2 XPS, LEED, XAS, SEM, AFM, TEM, NSOM, SPR, SERS, static and dynamic contact angle measurements, Ellipsometry.

Final Draft

300 Level courses CHE(NCL):3-001: Mathematical Methods: 2-0-0-2 Determinants and Matrices : Orthogonal Matrices, Hermitian Matrices, Unitary Matrices, Dioganalisation of Matrices, Vector analysis : Scalar and Vector product, Triple scalar and vector product, Gradient, Divergence, Curl, Vector Integration, Gauss Theorem, Stokes Theorem. Vector Analysis in Curvilinear coordinates and Tensors, Infinite Series: Fundamental Concepts, Convergence tests, Taylors expansion, Power Series, Special Functions: Gamma Function, The Beta Function, Differential Equations: Series SolutionFrobnius Method, Bessel Functions, Legendre Functions, Hermite Functions, Laguerre Functions, Fourier Series, Applications of Fourier Series, Fourier Transforms CHE(NCL):3-002: Numerical Methods: 2-0-0-2 Fortran and Linux basics, Solution to the linear algebraic equations, Eigen Values problems, Interpolation and extrapolation, Random number and sorting, Minimization and maximization of functions, Modeling of data CHE(NCL):3-003: Electronic structure theory: 2-0-0-2 Post-Hartree-Fock methods: Moller-Plesset perturbation theory (MP2, MP3, and MP4), Configuration Interaction (CI), Coupled-Cluster single double (triple) (CCSD(T))– performance of various methods for the prediction of van der Waal and hydrogen bonding interactions, spectral properties. Density functional theory based methods: Hybrid and Minnesota functional – Application of DFT methods (excitation energy calculations). Density functional methods with Dispersion correction (Grimme’s approaches). Car-Parrinello Molecular Dynamics (CPMD) and Born-Oppenheimer Molecular Dynamics (BOMD). CHE(NCL):3-004: Molecular modeling and simulation: 2-0-0-2 Molecular Mechanics: Features of molecular mechanics - Force Fields: Bonds structure and bending angles, Electrostatic Vander Waals and non-bonded interactions, Hydrogen bonding - Derivatives of molecular mechanics energy function - Calculating thermodynamic properties - Force Field for inorganic systems - Energy minimization, Molecular Dynamics Simulation: Molecular Dynamics using simple models, Molecular Dynamics with continuous potentials, Solvent effects, Conformational changes, Thermostats, Barostas, Lincs and shake algorithms, Monte Carlo simulation Methods, sorption, Applications of Molecular Modeling CHE(NCL):3-006: Computational materials design: 2-0-0-2 Solids, Drude and Sommerfield theories of metals, Kronig-Penning model, Tight-Binding approximation, band structure, density of states, prediction of electrical and magnetic properties, Prediction of properties of organic molecules and polymers, Introduction to Multiscale Modeling and Simulations and applications. Monte Carlo simulation in various ensembles, Gas sensing properties of various porous materials using grand canonical Monte Carlo method, Dissipative particle dynamics, Mesoscale dynamics and applications. CHE(NCL):3-008: Carbohydrate chemistry: 2-0-0-2 Mono and disaccharides, polysaccharides, Bacterial polysaccharides, starch and cellulose, derivatives of cellulose, Protecting groups, Glycosylation reactions, Dynamics and interactions, carboxy methyl cellulose and gun cotton, structure, Conformational analyses, glycoconjugates, Immunology of carbohydrates.

Final Draft

CHE(NCL):3-015: Chemistry and biology of Heterocycles: 2-0-0-2 Privileged heterocycles, Electronic properties, reactivity (electrophilicity and nucleophilicity), Synthetic methodologies, Biological properties of Natural products and drug candidates, Biosynthesis, Dimeric compounds and related stereochemistry CHE(NCL):3-023: Homogeneous Catalysis: 1-0-0-1 Organometallic Catalysis, Applications in organic synthesis: Olefin Isomerization, C-C Coupling reactions: Heck, Suzuki, Stille and Sonogashira reactions, Alkene and Alkyne Metathesis, C-Heteroatom coupling: Hydroamination, Olefin Oxidation, C-H activation, Oxidation reactions, hydrogenation of Alkenes, Industrial Applications. CHE(NCL):3-028: Materials and devices for energy conversion: 2-0-0-2 Design of organic and Inorganic semiconductors, Approaches to process organic semiconductors by covalent and non covalent modifications, band edges and band gaps, Modulation of charge transport properties, kinetics of electron transfer, Design of small molecule dyes for DSSC, Electron transfer at interfaces, Transistors and solar cells, Fabrication of Devices, Device characterisation using dark current, IV curves under illumination, IPCE, Calculation of Voc, Jsc, Vpp, Ipp, FF and Pmax. hybrid solar cells CHE(NCL):3-029: Functional Ceramics: 1-0-0-1 Advanced Electronic Ceramics, high temperature ceramic super conductors, Dielectric ceramics, microwave ceramics, low k materials, SOFC materials, solid-ionic conductors, phosphor materials, Impedance analysis, varistors, sensors, ceramic magnets, thermal shock resistance and super plastic ceramics. CHE(NCL):3-030: Modern Magnetic Materials: 1-0-0-1 Types of magnetism, molecular field theory, measurement techniques, magnetoresistance (AMR, GMR, CMR, TMR), hard and soft magnets, New magnetic materials, applications. CHE(NCL):3-031: Porous structures: 2-0-0-2 Definitions, Micro-Porous and Mesoporous Solids, Structural Chemistry of Zeolite Framework Types, MOFs, COFs, Synthesis, Structure Determination, Role of the Structuredirecting Agents, The Chemistry of Microporous Framework Solids, Adsorption and Diffusion, Catalytic Applications, hydrogen storage, separation, CO2 sequestration, sensors, CHE(NCL):3-034: Electrochemical power sources: 2-0-0-2 Energy scenario, emissions and global warming, fuel cells, Thermodynamic potentials, electrochemical processes and electrode kinetics, Proton exchange membranes, proton conducting mechanisms, recent advances, Operating conditions, overview of characterization techniques, technical aspects, advantages, materials, significances and challenges, Materials for supercapacitor applications, recent advances in the system development, battery vs. supercapacitor, modern technologies, challenges and prospects. CHE(NCL):3-035: Alternate energy materials: 2-0-0-2 Energy scenario, Non-renewable and renewable energy sources; description of renewable sources and their importance. Technologies for biomass energy conversion, Solar energy, Wind Turbines, Geothermal Technologies; Applications; Sustainable sources of hydrogen; Fuel cell technologies; Hydrogen storage and distribution; Applications and feasibility assessment; Science, technology and policy of energy conservation; Strategies for enhancing role of renewable energy.

Final Draft

CHE(NCL):3-037: Hydrogen generation and storage: 2-0-0-2 Sustainable sources of hydrogen; Fuel cell technologies; Hydrogen storage and distribution; Applications and feasibility assessment; Science, technology and policy of energy conservation; Strategies for enhancing role of renewable energy. CHE(NCL):3-046: Polymers and Colloidal Solutions: 2-0-0-2 Intermolecular forces and potentials, Overview of Statistical physics, DLVO theory, charged colloids, Poisson Boltzmann theory, Debye radius, Bjerrum length, electrophoresis, zeta potential, diffusion, Hydrodynamic interactions. Brief overview of Phase transitions in hard sphere colloids, Random walk, self avoiding random walk, flexible polymers, persistence length, Excluded volume interactions, Polymer solutions in the dilute limit/semi-dilute limit, Entropy of mixing, theta temperature, rubber elasticity, Polyelectrolytes, polymer at surfaces: Brushes, polymer dynamics. CHE(NCL):3-048: Controlled Radical/Living Polymerizations and Macromolecular Architectures: 2-0-0-2 Controlled or Living Radical Polymerization, TEMPO-mediated polymerization and atom Transfer radical Polymerization (ATRP), Kinetics of ATRP, Reversible Addition Chain Fragmentation Transfer (RAFT), Nitroxide mediated polymerization (NMP), Ring opening Metathesis polymerization (ROMP), living ROP, Macromolecular architectures using controlled living polymerizations CHE(NCL):3-051: X-Ray Diffraction and Structure of Solids: 2-0-0-2 Introduction to X-ray crystallography,Crystal growth, evaluation and mounting, Symmetry and space group determination, Background theory for data collection, Data collection using four-circle diffractometers, Area detectors,Crystal lattices, Structure factors, Crystal symmetry, Structure solutions, Structure refinement, An introduction to maximum entropy, Least squares fitting of parameters, Practical aspects of structure refinement, Crystallographic Database, Structure solution from Powder Diffraction Data CHE(NCL):3-052: NMR spectroscopy: 2-0-0-2 Quantum Mechanics of NMR, Multinuclear NMR spectroscopy, Periodic table of NMR, Heteronuclear double resonance experiments, Magnetization transfer and signal enhancement, NMR of diamagnetic and paramagnetic compounds, Multidimensional NMR: 2D NMR, 1H-1H correlations, Heteronuclear Correlation Spectroscopy, 2D Exchange (EXSY), 2D NOESY, ROESY, DOSY Structure elucidation of small molecules, NMR of macromolecules, Multidimensional NMR Spectra, NMR Spectroscopy of Solids, 2D experiments in solids, semi rigid systems: HR MAS, Magnetic Resonance Imaging: In Vivo NMR, Imaging, MRI, functional MRI, NMR imaging of materials. CHE(NCL):3-053: Mass spectrometry applications: 2-0-0-2 Applications to analyze molecular, macromolecular and biological samples, Sample Preparation Protocols, Drug Metabolism and Pharmacokinetics (DMPK), Development of Quantitative analytical methods using mass spectrometry, Application to some model drugs, Metabolomics , Proteomics, GC-MS, LC-MS, MALDI-TOF, GC-TOF, TOF/TOF MS, LC-ESIMS, Protein Database search (MASCOT), Clinical Mass Spectrometry, CHE(NCL):3-055: Small Angle Scattering Techniques: 2-0-0-2 SAXS and Fourier Transforms, General Theorems in Small Angle Scattering: Particulate systems: Porod and Guinier regimes, Pair density distribution functions, Single particle form factor for spheres, rods and plates, polydispersity, Structure factors for equilibrium Final Draft

concentrated particulate systems, measured structure factors for systems exhibiting polydispersity, Two phase systems: General Theorems, Detailed analysis of scattering from lamellar systems, relevance to semicrystalline polymers.

400 level courses Compulsory courses CHE(NCL):4-001: Project proposal writing & presentation: 0-0-4-2 CHE(NCL):4-002: Project proposal writing & presentation: 0-0-4-2 CHE(NCL):4-003: CSIR-800: 0-0-8-4

Final Draft

Annexure III-C

Course Content of Engineering Sciences

Special Meeting of Senate 08.06.2012

AcSIR – Engineering Sciences coursework

1. Common courses 2. Lab-wise courses a. CSIR- CBRI b. CSIR- CEERI c. CSIR- CIMFR d. CSIR- CMERI e. CSIR- CMMACS f. CSIR- CSIO g. CSIR- IICT h. CSIR- IIP i. CSIR- IMMT j. CSIR- NCL k. CSIR- SERC

AcSIR- Engineering Sciences Common courses Sl.No.

Courses No.

Title of the Course

L-T-P-C

1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14.

ENG ( ) 1-002 ENG ( ) 1-003 ENG ( ) 1-004 ENG ( ) 1-005 ENG ( ) 1-006 ENG ( ) 1-007 ENG ( ) 2-001 ENG ( ) 2-002 ENG ( ) 2-003 ENG ( ) 2-004 ENG ( ) 2-005 ENG ( ) 2-006 ENG ( ) 2-007 ENG ( ) 2-007

Mathematics for Engineers Numerical Methods in Engineering Statistical methods for engineers Transport phenomena Thermodynamics and Statistical Mechanics Reaction and Reactor Engineering Optimization Techniques in Engineering Soft Computing Finite Element Methods Finite Element Method for Fluid Dynamics Computational Fluid Flow & Heat Transfer Digital Signal Processing & Applications Advanced concrete technology Dynamics of Structures

3-0-0-3 2-0-2-3 2-0-2-3 3-0-2-4 2-0-2-3 2-0-2-3 3-0-2-4 3-0-2-4 3-0-2-4 3-0-2-4 3-0-2-4 2-1-0-3 2-0-2-3 2-0-2-3

Title of the Course

L-T-P-C

Numerical Methods Advanced Geotechnical and Foundation Engineering Engineering Materials for Infrastructure Analysis of Building Structure Research Methodology for Engineers Laboratory - I Geotechnical Engineering, Materials and Environmental science and Technology Design of Building Structures Disaster Resistant Building System - I Concrete Technology Planning, Regulations & Management of Buildings Industrialized Building Systems Repair, Rehabilitation & Retrofitting of Structures Environmental Impact Assessment Sustainable Design and Energy Efficient Building Systems Construction, Planning & Management Fire Protection Engineering Environmental Engineering & Management Advanced Seismology Engineering of Problematic Soil Optimization Techniques Deep Excavation Health Monitoring of Building Structures Tall Buildings & Structures Behaviour of Metal Structures Rock Mechanics Landslide Disaster Mitigation Laboratory - II Structural Engineering & Fire Engineering

3-0-0-3 3-0-0-3 3-0-0-3 3-0-0-3 2-0-0-1 0-0-4-2

CSIR-CBRI Sl.No. Courses No. ENG(CBRI) 1-137 1. ENG(CBRI) 1-139 2. ENG(CBRI) 1-141 3. ENG(CBRI) 1-143 4. ENG(CBRI) 1-145 5. ENG(CBRI) 1-147 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 25. 26. 27.

ENG(CBRI) 1-136 ENG(CBRI) 1-138 ENG(CBRI) 1-140 ENG(CBRI) 1-142 ENG(CBRI) 1-144 ENG(CBRI) 1-146 ENG(CBRI) 1-148 ENG(CBRI) 1-150 ENG(CBRI) 1-152 ENG(CBRI) 1-154 ENG(CBRI) 1-156 ENG(CBRI) 1-158 ENG(CBRI) 1-160 ENG(CBRI) 1-162 ENG(CBRI) 1-164 ENG(CBRI) 2-138 ENG(CBRI) 3-136 ENG(CBRI) 3-138 ENG(CBRI) 3-140 ENG(CBRI) 3-142 ENG(CBRI) 1-166

3-0-0-3 3-0-0-3 3-0-0-3 3-0-0-3 3-0-0-3 3-0-0-3 3-0-0-3 3-0-0-3 3-0-0-3 3-0-0-3 3-0-0-3 3-0-0-3 3-0-0-3 3-0-0-3 3-0-0-3 3-0-0-3 3-0-0-3 3-0-0-3 3-0-0-3 3-0-0-3 0-0-4-2

28.

ENG(CBRI) 2-137

Disaster Resistant Building System II

3-0-0-3

CSIR-CEERI Sl.No. 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19.

Courses No. ENG(CEERI) : 1-001 ENG(CEERI) : 1-206 ENG(CEERI) : 2-206 ENG(CEERI) : 2-208 ENG(CEERI) : 2-209 ENG(CEERI) : 2-210 ENG(CEERI) : 2-211 ENG(CEERI) : 2-212 ENG(CEERI) : 2-213 ENG(CEERI) : 2-215 ENG(CEERI) : 2-216 ENG(CEERI) : 2-217 ENG(CEERI) : 2-218 ENG(CEERI)32 : 2-219 ENG(CEERI) : 2-220 ENG(CEERI) : 2-221 ENG(CEERI) : 2-222 ENG(CEERI) : 2-223 ENG(CEERI) : 2-224

20.

ENG(CEERI) : 2-225

21. 22.

ENG(CEERI) : 2-226 ENG(CEERI) : 2-227

23. 24. 25. 26. 27. 28.

ENG(CEERI) : 2-228 ENG(CEERI) : 2-231 ENG(CEERI) : 2-232 ENG(CEERI) : 2-233 ENG(CEERI) : 2-234 ENG(CEERI) : 2-235

29.

ENG(CEERI) : 2-236

30. 31. 32. 33. 34. 35. 36. 37. 38. 39. 40. 41. 42. 43. 44. 45.

ENG(CEERI) : 3-001 ENG(CEERI) : 3-211 ENG(CEERI) : 3-212 ENG(CEERI) : 3-213 ENG(CEERI) : 3-214 ENG(CEERI) : 3-215 ENG(CEERI) : 3-216 ENG(CEERI) : 3-217 ENG(CEERI) : 3-218 ENG(CEERI) : 3-221 ENG(CEERI) : 3-222 ENG(CEERI) : 3-223 ENG(CEERI) : 3-224 ENG(CEERI) : 3-225 ENG(CEERI):3-227 ENG(CEERI) : 3-228

Title of the Course Research Methodology Technical Communication Project Management System Design for Process Control Applications System Modeling and Design Languages Intelligent Sensor Systems Real-time Embedded System Design Advanced Signal and Image Processing Power Electronics and AC/DC Drives Process Control Applications Laboratory System Modeling Laboratory Intelligent Sensor Systems Laboratory Real-time Embedded System Design Laboratory Advanced Signal and Image Processing Laboratory Power Electronics and AC/DC Drives Laboratory Physics of Semiconductor Materials and Devices Unit Processes in Semiconductor Technologies CMOS Digital VLSI Design Characterization Techniques for Semiconductor Materials, Technology and Devices Semiconductor Processing Technologies Laboratory

L-T-P-C 1-1-0-2 2-0-0-2 2-0-0-2 3-0-0-3 3-0-0-3 3-0-0-3 3-0-0-3 3-0-0-3 3-0-0-3 0-0-4-2 0-0-4-2 0-0-4-2 0-0-4-2 0-0-4-2 0-0-4-2 4-0-0-4 3-0-0-3 3-0-0-3 3-0-0-3

CMOS-based Physical Design Laboratory Semiconductors Related Characterization and Measurement Techniques Laboratory HDL-based Digital Design Laboratory Electromagnetic Theory and Transmission Lines Microwave Communication Numerical Techniques and CAD of Microwave Tubes Microwave and Millimeter-Wave Tube Technology Microwave Components Characterization and Tube Processing Techniques Laboratory Microwave Devices Characterization and Tube Subassembly Fabrication Laboratory Advanced Self-study (Special Topic) MEMS Technology, LTCC and Packaging Physics and Design of MEMS and Microsensors Nanoelectronic Devices and Technologies Advanced VLSI Technologies and Devices CMOS Analog Design Advanced VLSI System Architectures Optoelectronic Materials, Devices and Technologies Photonic Materials, Devices and Technologies MEMS Technology, LTCC and Packaging Laboratory Design of MEMS and Microsensors Laboratory Nanoelectronic Technologies Laboratory Study and Seminar on Advanced VLSI Technologies CMOS Analog Design Laboratory Optoelectronic Devices and Technologies Laboratory Photonic Devices and Technologies Laboratory

0-0-4-2 0-0-4-2

0-0-4-2

0-0-4-2 4-0-0-4 2-0-0-2 4-0-0-4 3-0-0-3 0-0-6-3 0-0-6-3 0-2-4-4 3-0-0-3 3-0-0-3 3-0-0-3 3-0-0-3 3-0-0-3 3-0-0-3 3-0-0-3 3-0-0-3 0-0-4-2 0-0-4-2 0-0-4-2 0-0-4-2 0-0-4-2 0-0-4-2 0-0-4-2

46. 47. 48. 49. 50. 51. 52. 53. 54.

ENG(CEERI) : 3-231 ENG(CEERI) : 3-232 ENG(CEERI) : 3-233 ENG(CEERI) : 3-234 ENG(CEERI) : 3-235 ENG(CEERI) : 3-236 ENG(CEERI) : 3-237 ENG(CEERI) : 4-001 ENG(CEERI) : 4-002

Slow-wave Devices – Principles and Design Fast-wave Devices – Principles and Design CAD of Microwave Tubes Laboratory High Power Microwave Systems and Applications Electron Emitters and Surface Characterization Plasma-Filled Microwave Sources Vacuum Microelectronic Devices Project Proposal Writing CSIR-800 Societal Programme

4-0-0-4 3-0-0-3 0-0-4-2 3-0-0-3 2-0-0-2 2-0-0-2 2-0-0-2 0-1-6-4 0-0-8-4

CSIR-CIMFR Sl.No.

Courses No.

Title of the Course

L-T-P-C

1. 2. 3. 4.

ENG(CIMFR):1-002 ENG(CIMFR):1-311 ENG(CIMFR):1-312 ENG(CIMFR):1-313

3-0-0-3 2-0-2-3 3-0-0-3 3-0-0-3

5.

ENG(CIMFR):1-314

6. 7. 8.

ENG(CIMFR):1-315 ENG(CIMFR):1-316 ENG(CIMFR):1-317

9. 10.

ENG(CIMFR):1-318 ENG(CIMFR):2-311

11. 12.

ENG(CIMFR):2-312 ENG(CIMFR):2-313

13.

ENG(CIMFR):2-314

14.

ENG(CIMFR):2-315

15. 16. 17. 18.

ENG(CIMFR):2-316 ENG(CIMFR):2-317 ENG(CIMFR):2-318 ENG(CIMFR):2-319

Mathematics for engineers Rock mechanics and ground control in mining ENGINEERING GEOLOGY MINE SAFETY LEGISLATIONS AND SAFETY MANAGEMENT ROCK MECHANICS INSTRUMENTATION AND MONITORING METHODS OF MINING ROCK EXCAVATION ENGINEERING RELIABILITY AND MAINTENANCE ENGINEERING IN MINING SYSTEMS ENVIRONMENTAL MANAGEMENT IN MINING INDUSTRY NUMERICAL SIMULATION AND STABILITY EVALUATION OF MINING STRUCTURES ADVANCED MINE VENTILATION AND ENVIRONMENT ADVANCED MINE SURVEYING AND SUBSIDENCE ENGINEERING MINE FIRE, ACCIDENTS AND DISASTERS - ANALYSIS AND PREVENTION MINE SAFETY EQUIPMENT: DESIGN, TESTING AND EVALUATION ADVANCED MINING METHODS MECHANISATION AND AUTOMATION FOR MINE SAFETY ROCK BLASTING AND FRAGMENTATION INDUSTRIAL PHYSIOLOGY AND ERGONOMICS

3-0-0-3 3-0-0-3 3-0-0-3 3-0-0-3 3-0-0-3 2-0-2-3 2-0-2-3 2-0-2-3 3-0-0-3 1-0-2-2 3-0-0-3 3-0-0-3 3-0-0-3 3-0-0-3

CSIR-CMERI Sl No. COURSE CODE

COURSE TITLE

L-T-P-C

ENG(CMERI) 1-001 RESEARCH METHODOLOGY

1-1-0-2

ENG(CMERI) 1-002 MATHEMATICS FOR ENGINEERS

3-0-0-3

ENG(CMERI) 1-381 INTRODUCTION TO MECHATRONICS SYSTEM

3-0-0-3

ENG(CMERI) 1-382 ADVANCED CONTROL SYSTEM

3-0-0-3

ENG(CMERI) 1-383 CAD & COMPUTER GRAPHICS

3-0-1-3

ENG(CMERI) 1-384 ELECTRICAL AND ELECTRONIC CIRCUITS & DEVICES

3-0-1-3

ENG(CMERI) 1-385 MACHINES & MECHANISMS

3-0-0-3

ENG(CMERI) 1-386 ROBOTICS

3-0-1-3

ENG(CMERI) 1-387 MICROCONTROLLERS & EMBEDDED SYSTEM DESIGN

3-0-1-3

ENG(CMERI) 1-388 DIGITAL SIGNAL PROCESSING & APPLICATIONS

3-0-1-3

ENG(CMERI) 1-389 ADVANCED MECHANICS OF SOLIDS

3-0-0-3

ENG(CMERI) 1-390 ADVANCED MECHANICS OF FLUIDS

3-0-0-3

ENG(CMERI) 1-391 MECHANICAL VIBRATIONS

3-0-0-3

ENG(CMERI) 1-392 COMPUTER LAB-I

1-1-2-3

ENG(CMERI) 1-393 FINITE ELEMENT METHODS

3-0-0-3

ENG(CMERI) 1-394 ANALYSIS AND SYNTHESIS OF MECHANISMS

3-0-0-3

ENG(CMERI) 1-395 COMPUTATIONAL FLUID FLOW & HEAT TRANSFER

3-0-0-3

ENG(CMERI) 1-396 COMPUTER LAB - II

0-0-4-2

ENG(CMERI) 2-381 INTRODUCTION TO COMPUTER VISION

3-0-1-3

ENG(CMERI) 2-382 ROBOTICS AND MACHINE INTELLIGENCE

3-0-1-3

ENG(CMERI) 2-383 INTRODUCTION TO NAVIGATION & DATA FUSION

3-0-1-3

ENG(CMERI) 2-384 MICRO SYSTEMS TECHNOLOGIES

3-0-1-3

ENG(CMERI) 2-385 ADVANCED MATERIALS

3-0-1-3

ENG(CMERI) 2-386 OPTIMAL CONTROL

3-0-1-3

ENG(CMERI) 2-387 PRECISION MACHINE DESIGN

3-0-1-3

ENG(CMERI) 2-388 NUMERICAL METHODS & COMPUTER PROGRAMMING

3-0-1-3

ENG(CMERI) 2-389 ELECTRO-MECHANICAL SYSTEMS DESIGN

3-0-1-3

ENG(CMERI) 2-390 ANALYTICAL MECHANICS

3-0-0-3

ENG(CMERI) 2-391 FINITE ELEMENT METHODS FOR FLUID DYNAMICS

3-0-1-3

ENG(CMERI) 2-392 NONLINEAR DYNAMICS & CHAOS

3-0-0-3

ENG(CMERI) 2-393 MECHANICS OF COMPOSITE MATERIALS

3-0-0-3

ENG(CMERI) 2-394 ROTOR DYNAMICS

3-1-0-4

ENG(CMERI) 2-395 COMPRESSIBLE FLOW

3-1-0-4

ENG(CMERI) 2-396 F LOW THROUGH TURBO MACHINES

3-1-0-4

ENG(CMERI) 2-397 FLUIDIZED BED DRYING

3-1-0-4

ENG(CMERI) 2-398 FLUIDIZED BED COMBUSTION & GASIFICATION

3-1-0-4

ENG(CMERI) 2-399 THERMODYNAMICS

3-1-0-4

ENG(CMERI) 2-400 PRINCIPLES OF CASTING SOLIDIFICATION

3-1-0-4

ENG(CMERI) 2-401 CONVECTIVE HEAT & MASS TRANSFER

3-1-0-4

ENG(CMERI) 2-402 TURBULENCE

3-1-0-4

ENG(CMERI) 2-403 STATISTICAL METHODS FOR ENGINEERS

3-1-1-4

ENG(CMERI) 2-404 ADVANCED ELECTRICAL DRIVES

3-1-0-4

ENG(CMERI) 3-001 ADVANCED SELF STUDY

3-1-0-4

ENG(CMERI) 3-002 PROJECT PROPOSAL - I

0-1-2-2

ENG(CMERI) 3-003 PROJECT PROPOSAL - II

0-1-2-2

ENG(CMERI) 3-004 CSIR-800 SOCIETAL PROGRAMME

0-0-8-4

ENG(CMERI) 3-381 ADVANCED COMPUTER ORGANIZATION & ARCHITECTURE

3-1-1-4

ENG(CMERI) 3-382 APPLIED SOFTCOMPUTING

3-1-1-4

ENG(CMERI) 3-383 OPTIMIZATION TECHNIQUES IN ENGINEERING

3-1-1-4

ENG(CMERI) 3-384 LOW POWERED EMBEDDED SYSTEM DESIGN

3-1-1-4

ENG(CMERI) 3-385 COMPUTER AIDED METROLOGY AND MACHINE VISION

3-1-1-4

ENG(CMERI) 3-386 ADVANCED FLUID FILM BEARINGS

3-1-1-4

ENG(CMERI) 3-387 WEAR OF MATERIALS & SURFACE MODIFICATIONS TECHNOLOGIES

3-1-1-4

ENG(CMERI) 3-388 FUNCTIONALIZATION OF SURFACE AND INTERFACES OF 3-1-1-4 BIOMATERIALS ENG(CMERI) 3-389 NANOTRIBOLOGY AND ITS APPLICATION TO MICROSYSTEMS

3-1-1-4

ENG(CMERI) 3-390 ADVANCED PASSIVE AND ACTIVE MAGNETIC BEARINGS 3-1-0-4 ENG(CMERI) 3-391 LATTICE BOLTZMANN AUTOMATA

3-1-0-4

ENG(CMERI) 3-392 ROBOTS WITH JOINT FLEXIBILITY: MECHANICS AND CONTROL

3-1-0-4

ENG(CMERI) 3-393 ARTIFICIAL INTELLIGENCE AND DATA MINING

3-1-0-4

ENG(CMERI) 3-394 ADVANCED COMPUTER VISION

3-1-0-4

ENG(CMERI) 3-395 ADVANCED NAVIGATION & DATA FUSION

3-1-0-4

ENG(CMERI) 3-396 MOBILE ROBOTICS

3-1-1-4

ENG(CMERI) 3-397 ADVANCED ROBOT DYNAMICS AND CONTROL

3-1-0-4

CSIR-CMMACS Sl.No. 1. 2. 3. 4. 5.

Courses No. ENG (CMMACS)- 1-001 ENG(CMMACS)-2-416 ENG(CMMACS)-2-417 ENG(CMMACS)-2-418 ENG(CMMACS)-2-419

6. 7. 8. 9. 10. 11. 12. 13.

ENG(CMMACS)-2-420 ENG(CMMACS)-2-421 ENG(CMMACS)-2-422 ENG(CMMACS)-2-423 ENG(CMMACS): 2-424 ENG(CMMACS)- 3-001 ENG(CMMACS)-4-001 ENG(CMMACS)-4-002

Title of the Course Research Methodology Transport Phenomena Finite Element Method Statistical and Computational Methods Global Navigation Satellite System (GNSS) theory and it applications Principles and Techniques of Mathematical Modelling High Performance Scientific Computing Nonlinear Dynamics Applied Computational Methods Numerical Analysis and Fortran Programming Advanced Self Study CSIR-800 Societal Programme Project proposal writing

L-T-P-C 1-1-0-2 2-1-0-3 3-0-0-3 2-1-0-3 2-1-0-3 2-1-0-3 2-1-0-3 2-1-0-3 2-1-0-3 3-0-0-3 0-2-4-4 0-0-8-4 0-1-6-4

CSIR-CSIO Sl.No. 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18.

Courses No. PHY/ENG(CSIO)-1-001 PHY/ENG(CSIO)-1-311 PHY/ENG(CSIO)-3-001 PHY/ENG(CSIO)-4-001 PHY/ENG(CSIO)-4-002 ENG(CSIO)-1-486 ENG(CSIO)-1-487 ENG(CSIO)-2-486 ENG(CSIO)-2-487 ENG(CSIO)-2-488 ENG(CSIO)-3-486 ENG(CSIO)-3-487 ENG(CSIO)-3-488 ENG(CSIO)-3-489 ENG(CSIO)-3-490 ENG(CSIO)-3-491 ENG(CSIO)-3-492 ENG(CSIO)-3-493

Title of the Course Research Methodology Mathematics for Engineers and Scientists Advanced Self Study Project proposal writing CSIR-800 Societal Programme Circuit Theory and Electronic Devices Mechanisms, Materials and Manufacturing Signal Processing Computer Aided Design and Simulation Human Physiology Digital Image Processing Statistical Analysis & Machine Intelligence Biological Control Systems Bio Instrumentation Agri-Physics and Agro Control Systems Agro Mechanical Systems Optical Instrumentation Opto-Mechanical Systems

L-T-P-C 1-1-0-2 3-1-0-3 0-2-4-4 0-1-6-4 0-0-8-4 3-1-0-3 3-1-0-3 3-1-0-3 3-1-0-3 3-0-0-3 3-0-2-4 3-0-2-4 3-0-2-4 3-0-2-4 3-0-2-4 3-0-2-4 3-0-2-4 3-0-2-4

CSIR-IICT Sl.No.

1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11.

Courses No.

Title of the Course

L-T-P-C

PES 611

Numerical methods and Process Modeling

3 Credits

PES 612 PES 613 PES 711 PES 614

Advanced Separation Processes Reaction Technology Process Engineering Advanced Chemical Engineering Thermodynamics

3 Credits 3 Credits 4 Credits 3 Credits

PES 621 PES 622 PES 721 PES 623 PES 624 PES 631

Advanced Process Design Advanced Process Optimization Process Integration and Intensification Membrane Technology Advanced Process Monitoring and Control Research Methodology & Technical Communication Skills

3 Credits 3 Credits 4 Credits 3 Credits 3 Credits 3 Credits

12. 13.

PES 632 PES 633

Artificial Intelligence in Process Engineering Biochemical Engineering

3 Credits 3 Credits

Courses No. ENG(IIP): 3-610 ENG(IIP): 2-611 ENG(IIP): 2- 593 ENG(IIP): 2- 612 ENG(IIP): 2- 613 ENG(IIP): 3- 614 ENG(IIP): 3- 615 ENG(IIP): 3- 616 ENG(IIP): 2- 617 ENG(IIP): 2- 594 ENG(IIP): 1-001

Title of the Course Advanced Thermodynamics for Mechanical Engineers Internal Combustion Engines Analytical Methods used in Petroleum Industry Tribology and Tribo – Component Design Chemistry of Lubricants Automotive Lubricants Automotive Emissions & Fuel Quality Automotive Test Equipments and Procedures Alternative Fuels Renewable Energy Conversion Technologies Research Methodology

L-T-P-C 3-0-0-3 3-0-0-3 2-0-4-4 3-0-0-3 3-0-0-3 3-0-0-3 3-0-0-3 2-0-2-3 3-0-0-3 3-0-2-4 1-0-0-1

CSIR-IIP Sl.No. 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11.

CSIR-IMMT Sl.No. 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15.

Courses No. ENGG (IMMT)-1-001 ENGG (IMMT)-2-626 ENGG (IMMT)-2-627 ENGG (IMMT)-2-628 ENGG (IMMT)-2-629 ENGG (IMMT)-2-630 ENGG (IMMT)-2-631 ENGG (IMMT)-2-632 ENGG (IMMT)-2-633 ENGG (IMMT)-2-634 ENGG (IMMT)-2-635 ENGG (IMMT)-2-636 ENGG (IMMT)-2-637 ENGG (IMMT)-3-626 ENGG (IMMT)-3-627

Title of the Course Research Methodology Computational Methods & Numerical Analysis Technologies for Mineral Resource Utilization Materials Characterization Technique Recycling of Material Resources Process Instrumentation & Control Science for engineers Fundamentals of Engineering Analysis Process Design & Simulation Advanced Extraction Methods Advanced Topics in Materials Resource Engineering Energy & Environment Mineralogy and Mineral chemistry Computational Fluid Dynamics Advanced Materials: Characterization and Processing

L-T-P-C 2-0-0-2 3-0-2-4 3-0-2-4 3-0-2-4 3-0-2-4 3-1-0-4 3-0-0-3 3-0-0-3 3-0-2-4 3-0-0-3 3-0-2-4 3-0-2-4 3-0-2-4 3-0-2-4 3-1-2-4

CSIR-NCL Sl.No. 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15.

Courses No. Eng(NCL):1-001 Eng(NCL):1-003 Eng(NCL):1-701 Eng(NCL):1-702 Eng(NCL):1-703 Eng(NCL):1-704 Eng(NCL):2-711 Eng(NCL):2-712 Eng(NCL):2-713 Eng(NCL):2-714 Eng(NCL):2-715 Eng(NCL):2-716 Eng(NCL):3-701 Eng(NCL):3-702 Eng(NCL):1-703

Title of the Course Research Methodology Numerical Methods and Programming Mathematical fundamentals Reaction and Reactor Engineering Transport phenomena Thermodynamics and Statistical Mechanics Multiscale simulations in materials Industrial flow modeling Data driven modeling Non-linear dynamics Modeling of biological systems Advanced separation processes Advanced topics in materials and processes Advanced topics in chemical engineering Transport phenomena

L-T-P-C 2-0-0-2 3-0-0-3 3-0-0-3 3-0-0-3 3-0-0-3 3-0-0-3 3-0-0-3 3-0-0-3 2-0-0-2 3-0-0-3 3-0-0-3 2-0-0-2 2-0-0-2 2-0-0-2 3-0-0-3

16. 17. 18. 19. 20. 21. 22. 23. 24. 25. 26. 27. 28. 29.

Eng(NCL):1-704 Eng(NCL):2-711 Eng(NCL):2-712 Eng(NCL):2-713 Eng(NCL):2-714 Eng(NCL):2-715 Eng(NCL):2-716 Eng(NCL):3-701 Eng(NCL):3-702 Eng(NCL):2-701 to 2-704 Eng(NCL):2-696 to 2-699 Eng(NCL):2-700 Eng(NCL):3-699

Thermodynamics and Statistical Mechanics Multiscale simulations in materials Industrial flow modeling Data driven modeling Non-linear dynamics Modeling of biological systems Advanced separation processes Advanced topics in materials and processes Advanced topics in chemical engineering Lab courses

3-0-0-3 3-0-0-3 3-0-0-3 2-0-0-2 3-0-0-3 3-0-0-3 2-0-0-2 2-0-0-2 2-0-0-2 0-0-4-2

Seminar Participation

0-1-0-1

Research Proposal I and Research Proposal II Symposium participation Critical survey

0-0-4-2 0-0-2-1 0-0-4-2

CSIR-SERC Sl.No. 1. 2.

Courses No. ENG(SERC): 2-930 ENG(SERC): 2-931

3. 4. 5. 6. 7. 8.

ENG(SERC): 2-932 ENG(SERC): 1-002 ENG(SERC): 2-933 ENG(SERC): 2-934 ENG(SERC): 2-935 ENG(SERC): 3-930

9. 10. 11. 12. 13.

ENG(SERC): 3-931 ENG(SERC): 3-932 ENG(SERC): 3-933 ENG(SERC): 1-930 ENGG(SERC) 1-906

14. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 25. 26. 27. 28. 29. 30. 31.

ENGG(SERC) 1-907 ENGG(SERC) 1-908 ENGG(SERC) 1-909 ENGG(SERC) 2-906 ENGG(SERC) 2-911 ENGG(SERC) 2-912 ENGG(SERC) 2-908 ENGG(SERC) 2-909 ENGG(SERC) 3-910 ENGG(SERC) 3-909 ENGG(SERC) 2-910 ENGG(SERC) 3-907 ENGG(SERC) 3-906 ENGG(SERC) 2-913 ENGG(SERC) 3-908 ENGG(SERC) 2-907 ENGG(SERC) 2-909 ENGG(SERC) 3-912

Title of the Course Renewable Energy Sources for a Sustainable Future Harnessing the power of Sun: Science and Technology of Solar Photovoltaics Energy Storage and Conversion: Science & Technology Mathematics for Engineers "View from the TOP" Seminar Series I Design and Engineering for Sustainability "View from the TOP" Seminar Series II Solar Photovoltaics: Power Electronics, Power Transmission and Energy Monitoring Advanced course on Lithium-Ion Batteries Design of Structures For Renewable Energy Bio Energy: The Plants Work & Let Us Reap Effective Presentation Skills and Dissertation Writing Instrumentation & Sensors for Structural Response Measurement Advanced Mechanics of Materials Computational Methods Advanced Engineering Mathematics Dynamics of Structures Bridge Engineering Earthquake Engineering RCC & Prestressed Concrete Structures Finite Element Technology-I Uncertainty Handling in Engineering Decision Making Soft Computing Plate and Shell Structures Metal Structure Behaviour and Design Health Monitoring of Structures -1 Repair & Rehabilitation of Concrete Structures New Composite Materials in Civil Engineering Applications Engineering for Natural Hazards Finite Element Technology-II Fatigue & Fracture of Engineering Structures

L-T-P-C 2-0-0-2 3-0-2-4 3-0-2-4 1-1-0-2 1-0-0-1 1-0-2-2 1-0-0-1 3-0-2-4 3-0-2-4 2-1-2-4 3-0-2-4 1-0-0-1 3-0-2-4 3-0-0-3 3-0-0-3 3-0-0-3 3-0-1-3 3-0-1-3 3-0-1-3 3-0-1-3 3-0-0-3 3-0-1-3 4-0-1-4 3-0-1-3 3-0-1-3 3-0-1-3 3-0-1-3 3-0-1-3 3-0-1-3 3-0-1-3 3-0-1-3

32. 33. 34. 35. 36. 37. 38. 39. 40. 41. 42. 43. 44. 45. 46. 47.

ENGG(SERC) 2-915 ENGG(SERC) 3-914 ENGG(SERC) 3-915 ENGG(SERC) 3-910 ENGG(SERC) 3-908 ENGG(SERC) 3-916 ENGG(SERC) 2-917 ENGG(SERC3) 3917 ENGG(SERC) 3-918 ENGG(SERC) 3-919 ENGG(SERC) 2-918 ENGG(SERC) 1-920 NGG(SERC) 3-921 ENGG(SERC) 3-922 ENGG(SERC) 1928 ENGG(SERC) 1-929

Engineering Materials Advanced Engineering Materials Probability and statistics Uncertainty Handling in Engineering Decision Making New Composite Materials in Civil Engineering Applications Structural Control Stability of Structures Health monitoring of structures – II

3-0-1-3 3-0-1-3 3-0-0-3 4-0-1-4 3-0-1-3 3-0-1-3 3-0-1-3 4-0-1-4

Soil structure interaction Advanced concrete technology Structural Design for Dynamic Loads Research Methodology & Professional Practice Advanced Self-study on Special Topic-A Advanced course on Special Topic-B Research Proposal Writing

3-0-1-3 3-0-1-3 3-0-1-3 2-0-0-2 1-1-6-4 3-1-4-4 1-1-4-4

CSIR-800 Societal Programme

0-0-8-4

AcSIR- Engineering Sciences Common courses ENG ( ) 1-002 : 3-0-0-3: Mathematics for Engineers Linear Algebra: Linear independence, Orthogonality, Vector Spaces and their bases and dimensions, Gram-Schmidt method for orthogonal basis set, Orthogonal projections. Matrices and Linear Mappings, Solution methods for Linear Simultaneous Equations, Eigenvalue problems. Vector Analysis : Vector differentiation and its applications, Vector operators: Grad, Div and Curl. Vector integration & related Integral Theorems (Gauss’ Divergence and Stoke’s Theorems) and applications. Cylindrical and Spherical Co-ordinate Systems. Differential Equations: Linear ODEs of first and second orders, Systems of first order ODEs, Applications of homogeneous and non-homogeneous linear second order equations. Partial Differential Equations, Solving various ODEs, PDEs, Fourier Series and Applications, The Laplace Transform. ENG ( ) 1-003 : 2-0-2-3: Numerical Methods in Engineering Introduction, finite floating point arithmetic, catastrophic cancellation, chopping and rounding errors; Solution of nonlinear equations; bisection method, secant method, Newton's method, fixed point iteration, Muller's method; Numerical optimization; Method of golden section search, Newton's method optimization; Solutions of linear algebraic equations; forwarding Gaussian elimination, pivoting, scaling, back substitution, LU-decomposition, norms and errors, condition numbers, iterations, Newton's method for systems, computer implementation; Interpolation; Lagrange interpolation, Newton interpolation, inverse interpolation; Numerical Integration; finite differences, Newton cotes rules, trapezoidal rule, Simpson's rule, extrapolation, Gaussian quadrature; Numerical solution of ordinary differential equations; Euler's method, Runge-Kutta method, multi-step methods, predictor-corrector methods, rates of convergence, global errors, algebraic and shooting methods, for boundary value problems, computer implementation ENG ( ) 1-004 : 2-0-2-3: Statistical methods for engineers Statistical Computing: Graphical representation of statistical data, Frequency distribution, Measures of central tendency and dispersion, Random variable and it’s expectation and variance, Probability models – Binomial, Poission and normal.

Bivariate Frequency Distributions. Scatter Diagram, Product Moment, Correlation coefficient and its properties (statements only), regression lines, correlation index and correlation ratio, Spearman rank correlation. Multiple linear regression, multiple correlation, partial correlation (without derivation). Random sampling (with replacement and without replacement), expectations and standard error of sampling mean (without derivation), expectation and standard error of sampling proportions. Point of estimation of parameters, Maximum likelihood estimation, interval estimate of parameters, test of significance based on t, F and CHI square distribution. Large sample tests, Tests based on Pearsonian frequency CHI-square. ENG ( ) 1-005 : 3-0-2-4: Transport phenomena Linear algebra and calculus relevant to transport phenomena Conservation equations Examples in transport phenomena ENG ( ) 1-006 : 2-0-2-3: Thermodynamics and Statistical Mechanics Classical Thermodynamics, ideal gases Solution thermodynamics Equilibrium thermodynamics Non-equilibrium thermodynamics Ensemble methods ENG ( ) 1-007 : 2-0-2-3: Reaction and Reactor Engineering Chemical kinetics Homogeneous reactor analysis and design Heterogeneous reactor analysis and design Special reactors

ENG ( ) 2-001 : 3-0-2-4: Optimization Techniques in Engineering Classical optimization methods, unconstrained minimization; Univariate, conjugate direction, gradient and variable metric methods, constrained minimization, Feasible direction and projections. Integer and Geometric programming, multi-objective optimization, genetic algorithms (GAs), multi-objective GA, simulated annealing techniques, engineering applications. ENG ( ) 2-002 : 3-0-2-4: Soft Computing Artificial neural network (ANN), Supervised and unsupervised learning of ANN, fuzzy logic, fuzzy membership function distributions, fuzzy logic rules, fuzzy and neuro-fuzzy inference systems, Genetic-fuzzy system, rough sets, The Hopfield Network; Support Vector Machines: Support vector machines and other kernel based learning algorithms, Implementation techniques for SVM, application of SVM for engineering problems; Evolutionary algorithms, hybrid-system. ENG ( ) 2-003 : 3-0-2-4: Finite Element Methods Review of matrix methods of structural analysis ; Stationary Principles, Rayleigh-Ritz method and Interpolation : Principle of stationary potential energy, Rayleigh-Ritz method, Stationary principles and governing equations, Finite element form RayleighRitz method, Method of Weighted Residuals. The Galerkin Method and the Weak Forms for various elastic systems. FEM formulation from a functional, Interpolation, C0 and C1 elements; Displacement based Element formulations: Overview of element stiffness matrix, Load formulations, Equilibrium and compatibility, convergence requirements, patch test, stress calculations, plane stress, plane strain, axisymmetric and solid finite elements, triangular, quadrilateral, tetrahedral and hexahedral elements. Isoparametric finite elements :1-D, 2-D and 3-D shape functions, Lagrangian and Serendipity family of elements, numerical integration, validity of isoparametric elements, element and mesh instabilities, coordinate transformations, handling of constraints; Plate bending elements :Plate bending theory, Mindlin and Kirchhoff element formulations, Concepts of locking, Full, reduced integration and selective reduced techniques, ENG ( ) 2-004 : 3-0-2-4: Finite Element Method for Fluid Dynamics Fundamental concepts; strong form, weak form, Galerkin approximation; matrix equations, element and global point of view; numerical integration – Guassian quadrature; temporal discretization - generalized trapezoidal rule; compressible and incompressible flows; implementation of the methods; issues related to high performance computing.

ENG ( ) 2-005 : 3-0-2-4: Computational Fluid Flow & Heat Transfer Discretisation procedure in Finite-difference and Finite-volume. Navier-Stokes, Energy equations. Staggered rectilinear grids. Explicit methods : MAC, SMAC. Implicit Methods, SIMPLE and SIMPLER. Matrix methods, conjugate gradient method, strongly Implicit Procedure. Grid-Generation:Algebraic, Transfinite, Poisson equation methods. Finitedifference Navier-Stokes solution on nonorthogonal grids, transformation. Collocated grids. Finite-volume methods on non-orthogonal grids. Turbulence modelling, k-e modeling. ENG ( ) 2-006 : 2-1-0-3:

Digital Signal Processing & Applications

Introduction: Elements of a Digital Processing system, advantage of digital processing over analog processing, continuous time signals, discrete time signals, sampling of analog signals, sampling theorem. Discrete time signals and systems: Classification, block diagram representation, analysis of linear systems, response of LTI systems to arbitrary inputs, convolution, causal systems, stability, finite duration and infinite duration impulse response, recursive and non-recursive systems, description by difference equations. Z transform: Direct and inverse Z transform, properties, poles and zeros, techniques of finding inverse Z- transform, analysis of LTI systems in z-domain. Frequency Analysis: Fourier series of continuous and discrete-time signals, power density spectrum, Fourier transform, cestrum, frequency-domain characteristics of LTI systems, LTI systems as filters. Discrete Fourier Transform: Frequency domain sampling properties of DFT, Linear filtering methods based on the DFT, frequency analysis of signals using DFT, FFT algorithms. Design of digital filter: Characteristics & design of filters.DSP Hardware: Introduction to DSP processors, their architecture ENG ( ) 2-007 : 2-0-2-3: Advanced concrete technology Cement: Composition of opc-manufacture-modified portland cements-hydration process of portland cements-structure of hydrated cement pastes Admixtures: Composition of opc-manufacture-modified portland cements-hydration process of portland cements-structure of hydrated cement pastes Aggregates: Mineral admixtures-slags-pozolanas and fillers-chemical admixtures-solutes retarders-air entraining agents- water proofing compounds-plasticizers and super plasticizers

Fresh concrete: Shape and mechanical properties-absorption and physical durabilitychemical stability and packing characteristics Properties of concrete: Workability-mix proportioning-mixes incorporating fly -ash -mixes for high performance concrete Interfacial transition zone-fracture strength-mechanical properties-high strength concrete-shrinkage-creep- other properties Durability of concrete: Basic consideration-Stability of constituents-Chemical AttackCorrosion of Reinforcing steel Special Concrete - High performance concrete, High volume fly ash concrete, Fibre reinforced concrete, Self compacting concrete, Ready mixed concrete, Geo-polymer concrete, Polymer modified concrete, Recycled aggregate concrete etc. ENG ( ) 2-007 : 2-0-2-3: Dynamics of Structures Introduction: dynamic vs. static response; types of dynamic loading: seismic, impact, wind, blast; Principles of dynamics - Formulation of equations of motion by different methods - single degree of freedom systems - free and forced response - effect of damping; Multi-degree of freedom systems -Formulation of equations of motion - Eigen values problems - Modes shapes and orthonormality of modes -Approximate methods of extraction of eigen values and natural frequency; Seismic response spectra Response spectra parameters; response spectra relationships; Dynamic response of MDOF systems - Mode superposition techniques -Numerical integration procedures; Continuous systems - Modeling - free and forced vibration of bars and beams; MDOFs : Response spectra analysis; SRSS and CQC combination methods; Introduction to frequency domain analysis; Time domain vs. frequency domain; Fourier series; the Fast Fourier transform (FFT);assessing frequency content; frequency based filtering; Application of finite element method in structural dynamics, wave propagation problems, introduction to random vibrations

CSIR-CBRI ENG(CBRI) 1-137

Numerical Methods

L-T-P-C 3-0-0-3

Objective

To acquaint the students with different numerical tools that are required to solve engineering problems

Modules

Interpolation, Errors in interpolation. Matrices: Numerical solution of ordinary differential equations, Numerical solution of Partial Differential Equations, Special fuctions: Introduction to Finite Element Method (FEM) and its applications Introduction to fuzzy logic, Artificial Neural Network Introduction to the softwares like MX-EXCELL, SPSS and MATLAB

ENG(CBRI) 1-139 Objective

Advanced Geotechnical and Foundation Engineering

L-T-P-C 3-0-0-3

To impart the necessary knowledge on geotechnical engineering required for building engineering and disaster mitigation with respect to geohazard.

Modules Introduction to Geotechnical engineering Deep foundation Ground Improvement Techniques Stability of Slope Reinforced Soil Environmental Geotechnics

ENG(CBRI) 1-141 Objective

Engineering Materials for Infrastructure

L-T-P-C 3-0-0-3

To study about building materials required for construction and maintenance of building infrastructure

Modules Conventional building materials Non-conventional building materials Advanced building materials Methods of characterization of building materials Types of cements, Chemical admixtures

ENG(CBRI) 1-143

Analysis of Building Structure

L-T-P-C 3-0-0-3

objective

To impart knowledge about advanced analysis methodologies that are required for efficient design of buildings

Modules

Static analysis – stiffness and flexibility methods Application problems using finite element technique, Introduction to non-linear analysis. Dynamic analysis Single degree of freedom system Multiple degree of freedom systems, Introduction to computer programs for dynamic analysis

ENG(CBRI) 1-145

Research Methodology for Engineers

L-T-P-C 2-0-0-1

Objective

To make the student aware on the ethics necessary to be followed in research and the methodologies generally adopted for carrying out data analysis and handling of primary and secondary data

Modules

Introduction to Research Methodology Designing and implementing a research project, Measurements in research, Communicating research results, Case studies Primary and secondary data, Analysis of data Quantitative analysis Professional ethics, Ethics in Research, Plagiarism, Communication Skills

ENG(CBRI) 1-147

Laboratory - I Geotechnical Engineering, Materials and Environmental science and Technology

L-T-P-C 0-0-4-2

Objective

To carry out laboratory experiments to evaluate the Geotechnical, physical and chemical properties of the material and to do the necessary characterisation

Modules

Geotechnical Laboratory Work Laboratory Soil Investigation Field Soil Investigation Materials and Environmental Science and Technology Laboratory Work Physical and Chemical testing of cement and other building material Instrumental methods for analysis of building materials

ENG(CBRI) 1-136

Design of Building Structures

L-T-P-C 3-0-0-3

Objective

To impart knowledge about the advanced design methodologies considering different environmental loading.

Modules

Design loads with special reference to earthquake and wind loads. Wind effects on buildings Concept of earthquake resistant design of buildings Introduction to plastic analysis in steel structures Computer applications in the design.

ENG(CBRI) 1-138 Objetive Modules

Disaster Resistant Building System - I

L-T-P-C 3-0-0-3

To educate about the earthquake resistant foundation system and Fire safety system in buildings Earthquake Resistant System Introduction to geotechnical earthquake engineering and seismic properties of soil Seismic bearing capacity of shallow foundations Seismic analysis of pile foundation Introduction to earthquake resistant building system Fire safety system in buildings Fundamentals of fire Growth and spread of fire Reaction to fire characteristics and fire retardant materials and techniques Smoke movement and control Fire dynamics and modelling Fire detection and Fire extinguishment.

ENG(CBRI) 1-140 Objective Modules

Concrete Technology

L-T-P-C 3-0-0-3

To make the students aware about the advancements that are taking place in the area of concrete technology Advances in Concrete Durability of concrete Special Concrete Concrete Technology - Sustainable & durable construction with concrete Quality Control

ENG(CBRI) 1-142

Planning, Regulations & Management of Buildings

L-T-P-C 3-0-0-3

Objective

To make the students aware of different bye-laws and regulations pertaining to buidings and related projects.

Modules

Introduction to Building Projects Project - formulation, appraisal and evaluation Project Management Issues Legal Issues Case studies - Urban housing and other building projects

ENG(CBRI) 1-144

Industrialized Building Systems

L-T-P-C 3-0-0-3

Objective

To apprise the students about the newer techniques that are prevalent for the different types of building systems.

Modules

Introduction Standardization Building Systems Strategies for Industrialization Prefabricated Systems for Building Envelopes Case studies and design

ENG(CBRI) 1-146 Objective

Modules

Repair, Rehabilitation & Retrofitting of Structures

L-T-P-C 3-0-0-3

To impart knowledge about the techniques that are adopted for repair, rehabilitation and retrofitting of building structure. Condition Assessment of different types of buildings Innovative Repair Materials suitable for buildings Repair Techniques – Existing and innovative Quality Assurance and Control of old building structures Case Studies:- Buildings & Heritage structures

ENG(CBRI) 1-148

Environmental Impact Assessment

L-T-P-C 3-0-0-3

Objective

To impart knowledge on the effect of constructed projects on the environment and systematic analysis of the same.

Modules

Introduction and Scope Environmental Clearance Process in India Impact assessment Environmental Quality Standards Control measures Case Studies – Green Buildings

ENG(CBRI) 1-150

Sustainable Design and Energy Efficient Building Systems

L-T-P-C 3-0-0-3

Objective

To make the students aware about the sustainable design concept and to generate awareness about the energy efficient building systems

Modules

Introduction Challenges driving the need for Sustainable Design Building Performance Assessment Tools Insulation and Heat Transfer Case Studies - Integrated design process, Green / Sustainable design projects.

ENG(CBRI) 1-152

Construction, Planning & Management

L-T-P-C 3-0-0-3

Objective

To make the students aware about the different techniques that are adopted in building construction practices and their management and usage of different construction equipments.

Modules

Introduction - RCC and masonry system, pre-engineered and industrialized building system Planning Construction project management Estimation of project cost,

ENG(CBRI) 1-154

Fire Protection Engineering

L-T-P-C 3-0-0-3

Objective

To impart knowledge on different aspects of fire protection in building system and schemes of disaster mitigation.

Modules

Introduction to fire safety engineering Heat transfer mechanisms in fire & build up of untenability conditions Combustion flammability and retardency, Burning behaviour of materials Active and Passive fire protection

ENG(CBRI) 1-156

Environmental Engineering & Management

L-T-P-C 3-0-0-3

Objective

To impart knowledge on different aspects of pollutants, thrie effect on the environment and efficient management system.

Modules

Water and Wastewater Engineering. Air Quality and Modelling Solid Waste Management Emerging Technologies in Environmental Management Current trends and emerging technologies, contemporary issues.

ENG(CBRI) 1-158

Advanced Seismology

L-T-P-C 3-0-0-3

Objective

To impart concepts on the basic aspects of seismic waves, their propagation, related instrumentation and consequences on the design of buildings

Modules

Science of Earthquakes Seismic Waves, Magnitude & Intensity, Earthquake Source Mechanism, Seismic Instrumentation, Seismic Zoning Map, Site Response Studies, Source and Path effect, Seismic Hazard Analysis, Risk and estimation, Seismic Micro-zonation, Earthquake Prediction Studies, Seismic Alert Systems

ENG(CBRI) 1-160

Engineering of Problematic Soil

L-T-P-C 3-0-0-3

Objective

To educate the students of geotechnical engineering on the different problematic soils and the techniques of remediation.

Modules

Various problematic soils Difference between improvement and modification. Soft Soil Expansive Soil Loose Cohesionless Soil Various improvement techniques Organic Soil Contaminated Soil

ENG(CBRI) 1-162

Optimization Techniques

L-T-P-C 3-0-0-3

Objective

To impart knowledge about the techniques that are adopted for optimising different design aspects related to building

Modules

Introdiuction Types of optimization schemes Linear Optimization techniques Stochastic Programming etc

ENG(CBRI) 1-164

Deep Excavation

L-T-P-C 3-0-0-3

Objective

To impart knowledge on the problems associated with excavation and design of large excavation.

Modules

Introduction to the analysis and design of excavation Excavation methods and lateral supporting systems Lateral earth pressure Stability analysis Stress and deformation analysis of excavation Design of excavation supporting systems

ENG(CBRI) 2-138

Health Monitoring of Building Structures

L-T-P-C 3-0-0-3

Objective

The objective of the course is to highlight the importance of monitoring techniques for effective maintenance of buildings and analysis methodologies

Modules

Introduction monitoring systems of building Numerical modelling Experimental techniques Rehabilitation processes.

ENG(CBRI) 3-136

Tall Buildings & Structures

L-T-P-C 3-0-0-3

Objective

To make the students aware about the analysis and design methodologies of tall buildings

Modules

Introduction – Tall building systems – Analysis Methodology of tall building frames – Different types of loads multibay frames; Shear walls Coupled frames – Frame with shear wall; Principles of 3-D analysis of tall buildings; Perforated cores - Pure torsion, bending and warping of cores; Floor systems – Analysis; Elastic and inelastic stability of frames and shear walls; Analysis for Thermal Stresses; Other Tall structures.

ENG(CBRI) 3-138

Behaviour of Metal Structures

L-T-P-C 3-0-0-3

Objective

To impart knowledge on the advanced techniques of analysing metal structures and to characterise their behaviour.

Modules

Introduction Stability issues Thin plates and their use in buildings Steel columns and their behaviour with residual stress Use of light gauge structure Pre-stressing in steel structure.

ENG(CBRI) 3-140

Rock Mechanics

L-T-P-C 3-0-0-3

Objective

To study the behaviour of rock at site under different stress conditions and to assess its properties in field and in the laboratory as well

Modules

Introduction to rock mechanics Rocks, rock structures and their importance Surface and subsurface investigations Engineering rock mass classifications & their application Physico-mechanical properties of rocks Stresses in elastic and plastic ground conditions Excavation Methods Support design and instrumentation in tunnels and slopes Problems and their remedies in rock engineering Application of rock mechanics

ENG(CBRI) 3-142

Landslide Disaster Mitigation

L-T-P-C 3-0-0-3

Objective

Study on landslide to understand its behaviour, design of slope and control measure design

Modules

Introduction - Landslide Types and processes Application of Remote Sensing and GIS in Landslide studies Landslide Hazard and Risk Assessment Landslide Instrumentation SMR & Slope Stability Assessment – Landslide Control Measures Landslide case studies

ENG(CBRI) 1-166

Laboratory - II Structural Engineering & Fire Engineering

L-T-P-C 0-0-4-2

Objective

To impart knowledge on the different aspects of advanced concrete structures and consequences of fire in structural systems.

Modules

Structural Engineering: Experiments on concrete mix design, special concrete such as fiber concrete/geopolymer concrete; building dynamics; Non destructive tests- Schmidt hammer, UPV, corrosion analyzer, core cutting; Wind tunnel. Fire Engineering: Fire propagation index, Ignitability at various irradiances levels, Specific optical density of smoke, Toxicity index.

ENG(CBRI) 2-137

Disaster Resistant Building System II

L-T-P-C 3-0-0-3

Objective

To impart knowledge on the techniques to designing buildings which will withstand landslide and earthquake

Modules

Landslide Disaster Mitigation: Introduction - Landslide Types and processes - Landslide causes - Landslide Hazard and Risk Assessment - Landslide Investigation and failure mechanism - Landslide Instrumentation - Landslide Control Measures. Earthquake resistant building structure: Characteristics of earthquakes, analysis of structures

for earthquake loading, Linear Analysis — Codal Method, Demand Capacity Ratio Method; Nonlinear Pushover Analysis, Rapid visual screening and simplified evaluation of buildings, Strengthening of existing components — RC, Steel and FRP Jacketing. Introduction to Performance based Engineering Strategies. Introduction to Tsunami Disaster.

CSIR-CEERI ENG(CEERI) : 1-001 : Research Methodology : 1-1-0-2 Course Coordinator : Raj Singh Introduction, terminology, and scientific methods; Types of research; Research process and steps; Identifying a research problem; Literature survey, appreciation of existing literature, identification of knowledge gaps; Conception of novel approach to solve the problem; Role of theory, modeling, and simulation; Design of experiments, testing and characterization strategies; Quantitative methods and data analysis; Qualitative analysis; Communicating research results; Thesis writing and oral presentation; Ethics in research. ENG(CEERI) : 1-206 : Technical Communication : 2-0-0-2 Course Coordinator : Raj Singh Role and importance of technical communication; Effective written and oral communication; Ethical issues; Technical report writing; Technical / R&D proposals; Research paper writing; Letter writing and official correspondence; Emails; Oral communication in meetings and group discussions; Oral presentations; Use of modern aids. ENG(CEERI) : 2-206 : Project Management : 2-0-0-2 Course Coordinator : Raj Singh Introduction; Project formulation, evaluation and initiation; Project planning and scheduling; Risk management; Project execution and implementation; Project monitoring and control; Project closure; Project documentation; Leadership and teamwork issues; Complex projects; Advances and trends. ENG(CEERI) : 2-208 : System Design for Process Control Applications : 3-0-0-3 Course Coordinator : S. S. Sadistap and B. A. Botre Virtual instrumentation and measurements, Virtual instrument design approach using LabView; Data acquisition modules; Electronic system trends, design options, metrics and considerations; Electronic system development cycle; PIC family of microcontrollers based system design and programming; Interfacing techniques for memory and I/O devices; Process control and instrumentation; Process simulation and modeling; Design case studies. ENG(CEERI) : 2-209 : System Modeling and Design Languages : 3-0-0-3 Course Coordinator : K. Solomon Raju and Rahul Varma Overview of the system specification, modeling and design methodologies; Untimed model of computation; Synchronous model of computation; Timed model of computation; Modeling of computation interfaces; Basic concepts of system design specification,

modeling and simulation using VHDL, SystemC, and UML; Transaction level modeling (TLM) based methodologies; Fundamentals of system design using Saber. ENG(CEERI) : 2-210 : Intelligent Sensor Systems : 3-0-0-3 Course Coordinator : P. C. Panchariya and P. Bhanu Prasad Primary sensing principles and measurement variables; Sensor performance characteristics and terminology; Transducer measurement circuits; Signal conditioning circuits; Data conversion; Virtual instrumentation with LabView; Introduction of softcomputing techniques; Foundations of fuzzy approaches; Fuzzy rule based systems; Fundamentals of neural networks; Implementation of various learning algorithms; Competitive, associative and other special neural networks; Practical aspects of neural networks; Neural methods in fuzzy systems; Introduction to statistical pattern recognition; Dimensionality reduction; Classification; Validation; Data analysis with MATLAB; Introduction to intelligent sensor system and their structures; Advanced processing and control techniques; Smart sensors; Case study: the “electronic nose”; The future of intelligent sensor systems. ENG(CEERI) : 2-211 : Real-time Embedded System Design : 3-0-0-3 Course Coordinator : K. Solomon Raju Fundamentals of FPGA-based system design, Architecture of embedded processors, Advanced processor architecture concepts, architectures for digital signal processing and applications; Designing soft processors with FPGAs; Power/energy efficient embedded system design; Real-time programming and communication; Concurrent Programming, Synchronization and communication; Scheduling of uni-processor and multi-processors; Real-time operating systems (RTOS) organization, Concept of kernel design, RTOS scheduling, Case studies of VxWorks, QNX, TinyOS, and others; Programming with QNX or VxWorks; Embedded hardware building blocks, Embedded system level design, design space exploration and verification techniques. ENG(CEERI) : 2-212 : Advanced Signal and Image Processing : 3-0-0-3 Course Coordinator : J. L. Raheja and A. Karmakar Discrete-Time Signals and systems in time domain; Time-domain characterization of Linear Time Invariant (LTI) Discrete-Time Systems (DTS); Discrete Time Fourier Transform (DTFT), Discrete Fourier Transform (DFT), z-transform; LTI DTS in the frequency domain : transfer function, frequency response; Simple digital filters; 2-D filters; FIR and IIR filter design; DSP algorithm implementation issues and finite word length effects; Image sensor models; Image representations and properties; Noise models, Image de-noising, Image pre-processing; Segmentation, Histogram, Histogram equalization and its application; Edge detection algorithm; Motion detection algorithm; Application of edge, face and motion detection; Hough transform and its application.

ENG(CEERI) : 2-213 : Power Electronics and AC/DC Drives : 3-0-0-3 Course Coordinator : Rahul Varma and A. K. Dhakar Power Electronics : Need of Power conversion, Applications of power electronics; Power semiconductor devices : Diode, Thyristor, MOSFET, IGBT; Line frequency diode rectifiers; Switch-Mode DC-DC Converters : Introduction, Step-down (buck), Step-up (boost), Buck-boost, full-bridge DC-DC converter and comparison; Introduction of highfrequency inductors and transformers; Switch-mode DC-AC inverters : Single-phase, three-phase inverters, Effect of Blanking time; Switching DC power supplies : Overview of switching power supplies, DC-DC converters with electrical isolation, Control of switch-mode DC power supplies, Electrical isolation in the feed-back loop, designing feedback controllers in switch-mode DC power supplies; Power factor correction (PFC) Circuits; Introduction of soft-switching in DC-DC Converters; Introduction to electric drive systems. Understanding mechanical system requirements for electric drives; Basic principles of electro-mechanical energy conversion; DC motor drives and electronicallycommutated motor drives; Introduction to AC machines and space vectors; Induction motors : balanced, sinusoidal steady-state operation and speed control. ENG(CEERI) : 2-215 : Process Control Applications Laboratory : 0-0-4-2 Course Coordinator : B. A. Botre and S. S. Sadistap Laboratory practices and safety considerations; LabView usage and programming; Data acquisition module programming; Using PIC family of microcontrollers for electronic systems design; Buses and Interfacing memory and I/O devices; Process simulation and modeling. ENG(CEERI) : 2-216 : System Modeling Laboratory : 0-0-4-2 Course Coordinator : K. Solomon Raju, Pramod Tanwar and Rahul Varma Laboratory practices and safety considerations; Understand Xilinx FPGA architecture; Introduction to designing with Xilinx FPGAs using Xilinx EDK, Core Generator; Architecture wizard and pin assignment; ChipScope; Design of DSP sub-blocks using SysGen; Designing system blocks using synthesis tools; System design using Saber tools for various applications. ENG(CEERI) : 2-217 : Intelligent Sensor Systems Laboratory : 0-0-4-2 Course Coordinator : P. C. Panchariya and Santosh Kumar Laboratory practices and safety considerations; Sensor interfacing; Signal conditioning of various sensors such as temperature, gases, pressure, humidity etc.; sensor calibration and excitation; Data acquisition; Virtual instrument and GUI design; Analog and digital I/O; File I/O; Integration of sensor, DAQ and GUI modules; implementation of pattern analysis methods; Signal preprocessing; Dimensionality reduction; Classification; Implementation of Fuzzy systems; Implementation of neural network algorithms; Time series forecasting; Implementation of neuro-fuzzy algorithms on real-world data sets.

ENG(CEERI) : 2-218 : Real-time Embedded System Design Laboratory : 0-0-4-2 Course Coordinator : K. Solomon Raju and Pramod Tanwar Laboratory practices and safety considerations; Understanding of developing a PowerPC and MicroBlaze based embedded system by using Xilinx Embedded Development Kit (EDK); Basic hardware design steps; Adding a processor system to a FPGA Design; Adding IP to a hardware design; Adding custom IP to the bus; writing software applications; System simulation with RTOS support; Multi-processor system design and implementation. ENG(CEERI)32 : 2-219 : Advanced Signal and Image Processing Laboratory : 0-0-4-2

Course Coordinator : J. L. Raheja and A. Karmakar Laboratory practices and safety considerations; MATLAB experiments on LTI systems in time and frequency domain, transfer function, frequency response; Design of digital FIR filters using windowing, frequency sampling; Design of digital IIR filters using impulse invariant, bilinear transform method; Two-channel and multi-channel orthogonal filter bank design; MATLAB experiments on color space conversion, basic image processing operations; Implementing various edge detection techniques; Real-time implementation of edge detection using DSP board; MATLAB experiments on histogram equalization, face detection and motion detection. ENG(CEERI) : 2-220 : Power Electronics and AC/DC Drives Laboratory : 0-0-4-2 Course Coordinator : A. K. Dhakar Laboratory practices and safety considerations; Familiarization with power electronic components, Line frequency diode rectifiers, Different PWM techniques, Switch-mode DC-DC Converters, Single-phase and three-phase inverter, DC-DC isolated converters, Speed control of DC motor, Brushless DC motor drive, AC motor drives. ENG(CEERI) : 2-221 : Physics of Semiconductor Materials and Devices : 4-0-0-4 Course Coordinators : J. Akhtar and S. C. Bose Semiconductors; Inorganic and organic, single crystalline, polycrystalline, porous, amorphous crystal structures, and material properties; Si, GaAs, GaN, SiC; Energy band diagrams; Dielectric constant, permeability, permittivity, sheet resistance, resistivity, mobility, thermal conductivity and heat dissipation; Piezo-resistive and piezo-electric effects; Defects, dislocations and micro-plasma, phonon dynamics, ion-solid interactions; Electron transport in semiconductors, minority carrier life time, avalanche breakdown phenomena, Hall effect; Theory of p-n junction, Schottky barrier, MOSFETs and MESFETs, IMPATTs and BARRITTs; Hetro-structures, strained semiconductors; Photovoltaics and solar cell; Solid state sensors and transducers; MOS analysis.

ENG(CEERI) : 2-222 : Unit Processes in Semiconductor Technologies : 3-0-0-3 Course Coordinator : G. Eranna Crystal growth techniques, wafer preparation and shaping, chemical cleaning, thermal oxidation, photo-lithography, chemical etching (wet and dry), chemical vapor deposition techniques, thermal diffusion, ion implantation, metalization, chemical mechanical polishing, rapid thermal processing. ENG(CEERI) : 2-223 : CMOS Digital VLSI Design : 3-0-0-3 Course Coordinator : A. Karmakar Introduction to MOSFET from designer's viewpoint; MOS inverter : static and switching characteristics; MOS capacitor; Layers in VLSI design; Design rules and technology interface; Stick diagrams and Layout design; Propagation delay, Fan-out consideration; CMOS Latch-up; Scaling; Combinational MOS logic circuits : passtransistors/transmission gates, primitive logic gates, complex logic gates; Sequential MOS logic circuits : latches and flip-flops; Dynamic logic circuits; Clocking issues; CMOS subsystem design. ENG(CEERI) : 2-224 : Characterization Techniques for Semiconductor Materials, Technology and Devices : 3-0-0-3 Course Coordinator : K. J. Rangra and G. Eranna Resistivity, Contact resistance, barrier height, carrier and doping concentration, mobility and carrier life time measurement techniques; Test structures for technology characterization; Analysis of surfaces, interfaces, thin films and devices; E-beam based techniques, Scanning Electron Microscopy and allied techniques; Material analysis techniques; Scanning probe Techniques; Ion-beam based techniques; Interferometry based techniques for materials and device characterization; Optical characterization. ENG(CEERI) : 2-225 : Semiconductor Processing Technologies Laboratory : 0-0-42 Course Coordinator : G. Eranna Laboratory practices and safety considerations; Wafer preparation and shaping; Chemical cleaning; Thermal oxidation, photo-lithography; Wet chemical etching; Dry etching; Chemical vapor deposition; Thermal diffusion; Ion implantation; Metalization. ENG(CEERI) : 2-226 : CMOS-based Physical Design Laboratory : 0-0-4-2 Course Coordinator : A. Karmakar Laboratory practices and safety considerations; SPICE simulation; Schematic editor, Layout editor, DRC, LVS; Transfer and output characteristics NMOS transistor, parameter variations; CMOS inverter design, inverter threshold, noise margin, propagation delay; Layout of CMOS inverter, n-well design rules, LVS, static and

transient characteristics, DRC; 2-input NAND/NOR gate; D latch and flip-flop; Postextract simulation. ENG(CEERI) : 2-227 : Semiconductors Related Characterization and Measurement Techniques Laboratory : 0-0-4-2 Course Coordinator : K. J. Rangra and G. Eranna Laboratory practices and safety considerations; IV and CV Measurements; Resistivity, thickness, thin-film surface and bulk defects; grain size measurement; AFM/STM surface analysis; Stress and deformation measurements; Measurement of sheet resistance, junction depth, carrier mobility, doping profile estimation, minority carrier life-time measurement; Model parameter extraction experiments. ENG(CEERI) : 2-228 : HDL-based Digital Design Laboratory : 0-0-4-2 Course Coordinator : A. S. Mandal Laboratory practices and safety considerations; Introduction to HDLs; Simulation of behavioral, Architecture/RTL, data-flow and structural HDL code; Sub-system design using HDL : various adder architectures, BCD arithmetic, various counters, traffic-light controller, etc.; Mini-project. (SystemC, VHDL and/or SystemVerilog will be used as the HDL for the laboratory.) ENG(CEERI) : 2-231 : Electromagnetic Theory and Transmission Lines : 4-0-0-4 Course Coordinator : A. K. Sinha Maxwell’s equations; Wave equations and their solutions; Boundary Conditions and their applications; Electromagnetic energy and power flow; Poynting theorem. Transmission lines; Wave-guide and coaxial components. Scattering matrix representation; Propagation of electromagnetic waves through homogeneous, in-homogeneous, and anisotropic media. Surface resistance and RF resistance. Ferrite devices. Waveguides and resonators. Characteristic and interaction impedances. Quality factors (loss and diffractive). Impedance Matching. Measurement of “Q”, power, noise figure, Sparameters, dielectric constant and loss tangent, dispersion and impedance characteristics, and loss parameters. ENG(CEERI) : 2-232 : Microwave Communication : 2-0-0-2 Course Coordinator : V. V. P. Singh Ground/surface wave, space-wave, and sky-wave modes of communication; Troposphereic Communication; Line of sight communication and system performance; Active and passive repeaters and their design; Analog and digital communication; Mobile communication; Satellite communication system; Earth station design criteria and direct reception system; Satellite transponders and their design criteria; PhPHY(CEERI)-noise, intra-pulse and inter-pulse noises and their significance.

ENG(CEERI) : 2-233 : Numerical Techniques and CAD of Microwave Tubes : 4-0-0-4 Course Coordinator : V. Srivastava Numerical solution of linear and non-linear differential equations of higher orders; Analytical and numerical techniques to the solution of electromagnetic field problems; Numerical techniques for the electrical, thermal, and structural design of slow-wave and fast-wave microwave tubes; Spent beam analysis for efficiency enhancement; Special focusing techniques for multi-beam electron guns; PIC simulation techniques; Finite difference and finite element techniques; Method of moments applied to microwave devices. ENG(CEERI) : 2-234 : Microwave and Millimeter-Wave Tube Technology : 3-0-0-3 Course Coordinator : R. S. Raju Fundamentals of vacuum technology. Vacuum generation and measurement, and leak detection. Ultra-high vacuum techniques. Surface physics and analysis in relation to electron Emitters. Electron-tube grade materials and their characteristics. Chemical processing. Heat treatment and special techniques: brazing, sintering, sputtering, TIG/electron beam/laser welding, glass-to-metal and ceramic-to-metal sealing, loss coating, and helix fitting. Vacuum processing of integrated devices. Design of tools, jigs, and fixtures. Engineering / mechanical design of components. Special machining techniques. ENG(CEERI) : 2-235 : Microwave Components Characterization and Tube Processing Techniques Laboratory : 0-0-6-3 Course Coordinator : O. S. Lamba Laboratory practices and safety considerations; Scattering parameters; Measurement of impedance and characterization of cavities; Dispersion and impedance characterization of RF structures; RF loss measurements; UHV techniques; Heat treatment in protective atmosphere; Ceramic-to-metal sealing techniques; Chemical processing of components. ENG(CEERI) : 2-236 : Microwave Devices Characterization and Tube Sub-assembly Fabrication Laboratory : 0-0-6-3 Course Coordinator : L. M. Joshi Laboratory practices and safety considerations; Device characterization using spectrum analyzer, scalar/vector analyzer; Break-down tests; X-ray radiography; Cathode characterization using Auger and Thermal emission microscope; Hot RF characterization of devices; Metal-to-metal brazing techniques; Leak detection; TIG/laser welding; Vacuum processing of devices; Cathode fabrication.

ENG(CEERI) : 3-001 : Advanced Self-study (Special Topic) : 0-2-4-4 Course Coordinator : Senior Scientists This will involve readings from published literature or books about new frontiers on a specific topic related to the field of electronics under guidance of senior scientist(s). A report needs to be submitted and a seminar on the special topic needs to be presented. ENG(CEERI) : 3-211 : MEMS Technology, LTCC and Packaging : 3-0-0-3 Course Coordinator : B. D. Pant and P. K. Khanna Review of Silicon crystal and unit processes; Processing steps for MEMS device fabrication; photo-lithography and backside mask alignment; Surface and bulk micromachining techniques; Deep reactive ion etching; LIGA process; Wafer-level bonding and packaging techniques; LTCC technology, materials, LTCC process steps, bonding and packaging; Testing and characterization of technology; Reliability and residual stress issues. ENG(CEERI) : 3-212 : Physics and Design of MEMS and Microsensors : 3-0-0-3 Course Coordinator : Ram Gopal and K. J. Rangra Overview of Microsensors; Mechanical properties of materials and essentials of structural mechanics; Electro-mechanical, magneto-mechanical and piezo-based sensing; Structural elements for MEMS and microsensors (Beams, plates, cantilevers, bridges and diaphragms); Electrostatic sensing and actuation (parallel plate and torsional structures, time domain analysis); Micro-fluidics; Scaling laws and miniaturization; Microsystem design principles; MEMS simulation and design Tools; RF MEMS; Reliability issues in microsensors; Examples and applications of MEMS microsensors. ENG(CEERI) : 3-213 : Nanoelectronic Devices and Technologies : 3-0-0-3 Course Coordinator : Anil Kumar Low-dimensional structures (Quantum well, quantum wire, quantum dot, quantum confinement); Confinement energy level, band-gap enhancement, absorption-emission spectra, blue shift, luminescence; Nanoelectronic Devices (Single electron box, Coulomb blockade, single electron transistor, pump, turnstile, trap, memory); Simulation, Modeling of single electron devices and applications; Technology for fabrication of nanostructures and nanoelectronic devices; Next generation lithography techniques; Characterization of nanoscale materials and nanodevices. ENG(CEERI) : 3-214 : Advanced VLSI Technologies and Devices : 3-0-0-3 Course Coordinator : G. Eranna and W. R. Taube Overview of VLSI technology; Effect of scaling on MOS devices and interconnections; Hot electron degradations and drain engineering structures; Process and material requirements for VLSI devices; Advanced thin-film deposition and VLSI process techniques; High-k dielectric and low-k dielectric materials; Process integration of high-k

metal gate for nanoscale CMOS technology; Device characterization, failure diagnosis and reliability measurements; Carrier transport mechanisms, velocity saturation, ballistic transport; Nanoscale MOSFET, FinFET and Multi-gate FET; Emerging materials and future devices. ENG(CEERI) : 3-215 : CMOS Analog Design : 3-0-0-3 Course Coordinator : S. C. Bose Basic concepts of transistors and diodes, their modeling, large-signal and small signal analysis, CMOS technology, clock feed-through; Reference sources : bias circuits, bandgap reference circuit, cascode current mirror; Single-stage amplifier, common source amplifier, drain and gate amplifier, differential amplifier; Operational amplifier; Comparators; Switched-capacitor circuits; Introduction to data converters; Issues of analog layout and device noise. ENG(CEERI) : 3-216 : Advanced VLSI System Architectures : 3-0-0-3 Course Coordinator : A. S. Mandal Introduction and review of basic computer architectures, CISC and RISC processors; Pipelining, hazards, exception handling, optimization techniques, synchronous and asynchronous pipelining; Memory organization, caches, virtual memory, memory management; Arithmetic circuits, algorithms and architectures for high-radix adders, multipliers, sine-cosine and exponential computation; Instruction-level parallelism, superscalar, super-pipelined and VLIW architectures, array and vector processors; Multiprocessor architectures and parallel architectures, synchronization, memory consistency; DSP architectures; Performance improvement techniques; ASIP; Lowpower architectures; Fault-tolerant architectures; Case-study on Algorithm-toArchitecture; Future trends. ENG(CEERI) : 3-217: Optoelectronic Materials, Devices and Technologies : 3-0-0-3 Course Coordinator : C. Dhanvantri Optoelectronic Materials; Growth of Epitaxial materials; Characterization of Epitaxial Materials; Optoelectronic Devices (Light Emitting Diodes, Semiconductor Lasers, UV, Visible and IR Photo-detectors and Receivers, Solar Cells); Compound semiconductors and advanced electronic devices; Compound Semiconductor Technologies; Packaging of compound semiconductor components; Applications and trends. ENG(CEERI) : 3-218 : Photonic Materials, Devices and Technologies : 3-0-0-3 Course Coordinator : S. Pal Introduction to Photonics; Basic photonic components and their technologies; Propagation of Electromagnetic waves; Optical waveguides and optical fibers; Principle of optical fiber communications, Transmission capacity, Dispersion and losses in optical fiber; Coupled mode theory in guided wave systems; Materials and fabrication technologies; Types of waveguides; Basic photonics devices and components; Optical

sensors and sensing techniques; Optical MEMS; Fiber gratings and waveguide gratings; Photonic crystal based waveguides and devices; Packaging of photonic devices; Applications of photonic devices; Recent trends. ENG(CEERI) : 3-221 : MEMS Technology, LTCC and Packaging Laboratory : 0-0-4-2 Course Coordinator : B. D. Pant and P. K. Khanna Laboratory practices and safety considerations;; Wafer cleaning; Lithography : front and backside alignment; Bulk micro-machining; DRIE process; LPCVD; Metalization; Wafer bonding; Surface planarization; Wafer dicing; LTCC process; Packaging. ENG(CEERI) : 3-222 : Design of MEMS and Microsensors Laboratory : 0-0-4-2 Course Coordinator : Ram Gopal and K. J. Rangra Laboratory practices and safety considerations; MEMS design tools; Design of pressure sensors of various types; Design of gas sensors of various types; Acoustic, Ultrasonic, micro-resonator, ISFET; RF MEMS design and simulation. ENG(CEERI) : 3-223 : Nanoelectronic Technologies Laboratory : 0-0-4-2 Course Coordinator : Anil Kumar Laboratory practices and safety considerations; Fabrication of metal thin films by sputtering/e-beam/resistive-heating and measurement of film thickness by making steps using wet etching; Experiments on growth of Silicon nanoparticles and their optical characterization; Experiments with nanolithography and nanopatterning; Simulation of single electron devices using SIMON; Simulation of inverter circuit using SET in SIMON; Operation of AFM/STM; Analysis of AFM/STM images; Study of annealing effect on roughness/grain size of metal films by AFM/STM imaging and analysis. ENG(CEERI) : 3-224 : Study and Seminar on Advanced VLSI Technologies : 0-0-4-2 Course Coordinator : G. Eranna and W. R. Taube This will involve literature search, review and study of current research on materials, process methodologies and simulations, and novel applications related to advanced VLSI technologies and nanoelectronics. Simulation studies and experiments may also be carried out, where possible. A study report is to be submitted and a seminar is to be given. ENG(CEERI) : 3-225 : CMOS Analog Design Laboratory : 0-0-4-2 Course Coordinator : S. C. Bose Laboratory practices and safety considerations; I-V characteristics of MOSFET, estimation of early voltage; Clock feed-through and its minimization; Bias generation architecture simulation; Band-gap reference circuit simulation; Design and simulation of various amplifiers; Design and simulation of 2-stage CMOS operational amplifier; Layout of analog circuits.

ENG(CEERI):3-227 : Optoelectronic Devices and Technologies Laboratory : 0-0-4-2 Course Coordinator : C. Dhanvantri Laboratory practices and safety considerations; Lift-off process for Ohmic Contact on GaAs substrate; TLM measurements for specific contact resistance; RIE process for GaAs etching; LI Characteristics of 980 nm Laser Diode; Transistor characteristics of GaAs Power MESFET; LED Characteristics; Photoluminescence characterization of GaN epitaxial material; Characterization of PIN-FET receiver module. ENG(CEERI) : 3-228 : Photonic Devices and Technologies Laboratory : 0-0-4-2 Course Coordinator : S. Pal Laboratory practices and safety considerations; Measurement of refractive index and thickness of planar waveguides; Propagation loss measurement of planar waveguides; Design of 1x2 and 1x4 optical power splitter; Measurement of insertion loss, uniformity and polarization-dependent loss of a packaged 1x8 optical splitter at C+L band region; Design and simulation of Bragg gratings; Waveguide patterning by photo-lithography; Testing of MUX/DEMUX by DWDM test set-up; Chip-level testing: alignment of DUT (in a diced chip) to the source and the detector with x-y-z alignment stages. ENG(CEERI) : 3-231 : Slow-wave Devices – Principles and Design : 4-0-0-4 Course Coordinator : V. Srivastava and L. M. Joshi Classification and high frequency limitations of conventional electron tubes. Formation and confinement of an electron beam. Slow-wave structures, couplers and RF windows. Beam-wave interaction mechanism. Spent beam collection. Efficiency enhancement by phase-velocity tapering and multi-stage depressed collection. Different types of devices, their operation, and characteristics, High power and wide bandwidth issues. Future trends. ENG(CEERI) : 3-232 : Fast-wave Devices – Principles and Design : 3-0-0-3 Course Coordinator : A. K. Sinha Merits of fast-wave devices over slow-wave devices. Operating principle of a gyrotron and design of its components: magnetron injection gun, beam tunnel, RF interaction cavity, magnetic field, non-linear taper, RF window, mode converter and collector. Beamwave interaction and mode selection criteria. Other fast-wave devices: gyro-TWT, gyroklystron, peniotron and FEL. Applications of gyro-devices and future trends. High Power Microwave (HPM) Devices. ENG(CEERI) : 3-233 : CAD of Microwave Tubes Laboratory : 0-0-4-2 Course Coordinator : R. K. Sharma and S. K. Ghosh Laboratory practices and safety considerations; Components design : electron guns, slow-wave structures, fast-wave structures, RF cavities, RF windows, collectors; Electron

beam and RF wave interaction simulation; Thermal and structural design and simulation; CAD of complete tube; Computer aided engineering drawing. ENG(CEERI) : 3-234 : High Power Microwave Systems and Applications : 3-0-0-3 Course Coordinator : L. M. Joshi Special EW (Radar, ECM, ECCM) systems and their requirements in respect of microwave and millimeter wave devices; Types of jamming; Linear accelerators, Microtrons, Synchrotrons, Plasma heating systems, Proton accelerators, and Thermonuclear reactors; Other applications like imaging, spectroscopy, biomedical, industrial heating, electronic power conditioners, and modulators. ENG(CEERI) : 3-235 : Electron Emitters and Surface Characterization : 2-0-0-2 Course Coordinator : R. S. Raju Physics of electron emission, emission equation; Temperature limited and space-charge limited emission; Methods of determining work function; Oxide coated cathodes, Dispenser cathodes, Field emitters, Explosive emission cathodes, Secondary emitters; Fabrication and characterization of cathodes; Life testing and surface analysis techniques; Nano-cathodes. ENG(CEERI) : 3-236 : Plasma-Filled Microwave Sources : 2-0-0-2 Course Coordinator : Ram Prakash and U. N. Pal Plasma and its physical parameters; Saha equation and its relevance; Motion of charged particles in static and slowly varying electric and magnetic fields; Motion of relativistic charged particles; Types of gaseous discharge; Hollow-cathode discharge and other kinds of low-pressure discharges; General features of electrons emission, control and extraction of electrons and ions from plasma in DC and pulsed mode conditions; Plasma sources for axially symmetric electron beams; Plasma cathode electron gun (PCE-gun); Advantages of plasma filling in high power microwave devices; Operating principles, characteristics, and applications of different types of plasma-filled devices including the pasotron. ENG(CEERI) : 3-237 : Vacuum Microelectronic Devices : 2-0-0-2 Course Coordinator : R. K. Sharma Basic semiconductor technologies like reactive ion etching, photo-lithography, oxidation, CVD, sputtering, LIGA; MEMS technologies; Design considerations in vacuum microelectronic devices; Photonic band-gap structures, folded wave guide and ladder structures; Tera Hertz devices including reflex klystrons; Micro-fabricated devices like TWT and klystrino; Combination of vacuum and semiconductor technologies in microwave devices, including microwave power module and their applications.

ENG(CEERI) : 4-001 : Project Proposal Writing : 0-1-6-4 Course Coordinator : Raj Singh Definition of a scientific project proposal; Components of a proposal; Need and purpose of the proposal; Aims and objectives; Background and present status; Proposed methodologies and approaches; Scheduling and mile-stones; Resource allocation; Budgeting; Monitoring and evaluation mechanisms; Referencing and citing; Use of data, graphs, tables, figures; Proposal funding agencies and their formats. Every student needs to submit two proposals – one related to PhD research topic and the second in any field of electronics. ENG(CEERI) : 4-002 : CSIR-800 Societal Programme : 0-0-8-4 Course Coordinator : Raj Singh A project needs to be undertaken in rural area for 6-8 weeks duration aligned to the CSIR-800 programme. The theme of the project may be chosen from the CSIR-800 document or from any other government department related to benefiting and empowering the economically lower 800 million Indians by way of S&T innovations. The aim is to interact with underprivileged people in the villages and propose solutions in the area of health, agriculture, energy, water, food, education, etc.

CSIR-CIMFR ENG(CIMFR):1002

MATHEMATICS FOR ENGINEERS

L-T-P-C:3-0-03

Course Coordinators: Dr. Ajay Kumar Singh and Dr. M. Sundararajan Linear Algebra: Linear independence; Orthogonality; Vector Spaces and their bases and dimensions; GramSchmidt method for orthogonal basis set; Orthogonal projections; Matrices; Solution methods for linear simultaneous equations; Eigenvalue problem. Vector Analysis: Vector differentiation, Applications; Vector operators: Grad, Div and Curl. Vector integration and related Integral Theorems, Applications; Cylindrical and Spherical Co-ordinate Systems. Differential Equations: Linear ODEs of first and second orders; Linear second order equations, Applications; The Laplace Transform, Applications; Fourier Series and Applications; Partial differential equations of first and second orders; The Laplace and Wave Equations. ENG(CIMFR):1311

ROCK MECHANICS AND GROUND CONTROL IN MINING

L-T-P-C:2-0-23

Course Coordinators: Dr. Rajendra Singh and Dr. C. N. Ghosh Rocks and rock structures; Rock mass classification; Rock mass properties; Rock failure criteria; Stresses in elastic and plastic ground conditions; Effect of anisotropy and inhomogeneity on rock properties; In situ stresses and its measurements; Different types of ground excavations and effects of their instability; Design of roadways and pillars; Approaches of ground behaviour evaluation; Different types of rock reinforcement and support; Ground Control measures during different methods of mining; Rock bursts and bumps; Slope stability evaluation: Discontinuities and geomechanical properties of slope mass; Groundwater condition and its measurement; Mechanics of slope stability; Slope stability in weathered slopes; Case studies. ENG(CIMFR):1312

ENGINEERING GEOLOGY

L-T-P-C:3-0-03

Course Coordinators: Dr. A. Sinha and Dr. R. K. Goel Depositional textures and structures; Physics of deformation with surroundings, time and material; Planar and linear structures; Faults, folds, cleavages, dip, strike, contour, stratification, lamination, bedding; Unconformity & joints - their classification and Recognition in the field; Major structures and tectonics; Structures in igneous rocks and igneous intrusions; Geomorphology and structure morphotectonics; Mineral Exploration: Geological, Geophysical and Geochemical Prospecting; Study of geological structures; Management and utilisation of geological data; Coal geology; Hydrogeology. ENG(CIMFR):1313

MINE SAFETY LEGISLATIONS AND SAFETY MANAGEMENT

L-T-P-C:3-0-03

Course Coordinators: A. K. Ghosh and Dr. S. K. Singh Mine Safety Legislations: Mines Act; Mine Rules; Coal Mines Regulations; Metalliferous Mines Regulations; Mines and Minerals (Development and Regulations) Act; Mines Rescue Rules; Circulars; Other related industrial legislations, circulars, documents related to mine safety. Mine Safety Management: Requirements for effective safety management; Mine safety management system – background, objectives and structure; Different levels of safety management; Processes of safety management;

Hazard identification and risk assessment; Risk management, case studies; Concept of mine safety monitoring. Purpose and classification of safety monitoring. Mine safety monitoring techniques; Preparation of safety monitoring plan; Measurement of safety efficiency; safety audit; safety records. ENG(CIMFR):1314

ROCK MECHANICS INSTRUMENTATION AND MONITORING

L-T-P-C:3-0-03

Course Coordinators: Dr. P. K. Mandal and D. Kumbhakar Ground behaviour and instability in ground excavations; Methods of studying ground behaviours; Monitoring of ground behaviour in underground mines; Different types of field instruments used for rock mechanics instrumentation and monitoring – sensors and transducers, readout units, data acquisition systems, etc.; Rock mechanics testing equipment; Acoustic emission equipment; Monitoring of reinforcement and support system; Rock bolt pull tester; GPR based monitoring of underground structures; Field instrumentation and monitoring of slopes; Conventional and GPS based monitoring; Real-time monitoring; Communications/storage of data; Analysis of data and evaluation of ground stability. ENG(CIMFR):1315

METHODS OF MINING

L-T-P-C:3-0-03

Course Coordinators: Dr. Arun Kumar Singh and Amar Prakash Methods of exploration; Evaluation of mineral deposits; Mine planning; Surface and underground mining; Opening of mineral deposits; Shaft sinking; Methods of excavations; Explosive and Blasting; Conventional and special methods of mining; Mining Machinery and its applications. ENG(CIMFR):1316

ROCK EXCAVATION ENGINEERING

L-T-P-C:3-0-03

Course Coordinators: Dr. C. Swamliana and N. Kumar Rock Excavation by drilling and blasting; Study of the theories of rock penetration including percussion, rotary, and rotary percussion drilling; Rock fragmentation including explosives and the theories of blasting rock; Application of theory to drilling and blasting practice at mines, pits, and quarries; Mechanised Excavation of Rock; Classification and construction of extraction machineries; Different types of machineries and their suitability; Selection of equipments and machineries; Operational conditions; Safety measures; Performance monitoring; Condition monitoring and maintenance; Study of excavation stability; Excavation support design. ENG(CIMFR):1317

RELIABILITY AND MAINTENANCE ENGINEERING IN MINING L-T-P-C:3-0-0SYSTEMS 3

Course Coordinators: Dr. D. Basak and Dr. Ranjan Kumar Statistical methods in reliability: Basic statistics and probability theory; Reliability concepts: Reliability function, failure rate, MTTF, MTTR, mortality curve, useful life, availability, maintainability, system effectiveness; Reliability analysis and prediction: Time to failure distribution, exponential, normal, gamma, weibull distribution, system reliability evaluation, standby systems; Design for reliability: Design theory, design for reliability, design for maintainability, reliability improvement techniques; Maintenance engineering: Introduction, maintenance policies, failure, diagnosis, Markov maintenance, process maintenance support and logistics, maintenance management; Reliability and maintenance in mining: Failures in mining systems, reliability testing, machine maintenance management, human reliability, mine systems reliability improvement, reliability optimization. ENG(CIMFR):1ENVIRONMENTAL MANAGEMENT IN MINING INDUSTRY L-T-P-C:3-0-0318 3

Course Coordinators: Dr. (Mrs.) B. Prasad and Dr. R. Ebhin Masto Concept of sustainable and eco-friendly mining; Impacts of mineral exploration, mining, processing and utilization on environment; Air quality standards, air pollutant sources and health effects; Source and occurrence of waters in mines; Mine water contaminants and their natural attenuation; Acid mine drainage and mine water treatment; Soil conservation and erosion control, restoration of soils, Importance, threats, approaches for conservation and management of biodiversity; Methods of collection and analyses of water, soil, gaseous and particulate pollutants; Bio-monitoring and analytical techniques; EIA/EMP, Environmental clearance; Environmental Law, Legislation and Policies; Principles of mine closure plan; Environmental Hazard and Risk Assessment. ENG(CIMFR):2311

NUMERICAL SIMULATION AND STABILITY EVALUATION OF L-T-P-C:2-0-2MINING STRUCTURES 3

Course Coordinators: Dr. G. Banerjee and Dr. P. K. Mandal Different numerical methods; Inputs of numerical methods; Model generation; Application of Finite difference method; Finite element method; Distinct element method; Boundary elements method; Hybrid methods; Application of different numerical modelling methods and software for ground stability evaluation of mining structures; Validation of models; Design optimisation through numerical modelling; Case studies. ENG(CIMFR):2312

ADVANCED MINE VENTILATION AND ENVIRONMENT

L-T-P-C:2-0-23

Course Coordinators: Dr. N. Sahay and Dr. J. K. Pandey Mine Ventilation systems; Mine thermodynamics and computation of psychometric properties; Modes of heat transfer; Designing of climatic conditions in panels; Computation of volume flow; Application of Kirchoff’s second law to solve field problems; Hardy Cross Iterative method and its application to solve ventilation network problems; Thermodynamic principles applied to ventilation network analysis; Air Leakage; Recirculation and reversal of air flow; Pressure behavior of sealed-off area; Dynamic balancing of pressure technique; Ventilation survey and planning; Air conditioning; Environmental monitoring; Network analysis; Ventilation survey instruments; Simulations of mine ventilation network; Design of coal dust control plan; Noise and Vibrations; Mine Illumination. ENG(CIMFR):2313

ADVANCED MINE SURVEYING AND SUBSIDENCE ENGINEERING

L-T-P-C:2-0-23

Course Coordinators: Dr. K. B. Singh and A. Prakash Concepts of Surveying; Automatic Level; Digital Level & Optical Theodolites; Data collection procedures; GIS:GIS Data Models; Data Acquisition; Maps and Map Projections; Surveying using EDM; Total Station and its application in Mine Subsidence and Ground Movement Monitoring of Opencast Mine Slopes; 3D Scanning; 3D Ground/Mine Surface Modelling using Total Station; Section extraction and excavation volume computation in civil and mining application; Mapping. Subsidence: Causes and types of subsidence; Subsidence measurement methodologies and prediction; Environmental impacts of subsidence on land, buildings, ground water, forest cover, etc.; Safe limits of subsidence for different surface features and structures; Subsidence control measures.

ENG(CIMFR):2314

MINE FIRE, ACCIDENTS AND DISASTERS - ANALYSIS AND L-T-P-C:3-0-0PREVENTION 3

Course Coordinators: Dr. R. V. K. Singh and Dr. I. Ahmad Causes and types of mine fire; Fire risk assessment; Detection and Assessment of spontaneous heating/fire; Gas hazards; Methods of sampling of gases from fire area; Mine gas Analysis; Thermo-compositional Investigation; Environmental affects due to fire; Fire prevention and combating; Fire combat methods; Dealing with long standing fires; Fire fighting equipment. Types and Causes of mine accidents; Dangerous occurrences in mines; Study of mine accidents and its analysis; Mine accidents and disasters; Analysis of mine accidents and preventive measures. Types and causes of mine disaster; Mine inundation; Design of underground dams; Mine explosion; Mine rescue; Mine disaster control and mitigation. ENG(CIMFR):2315

MINE SAFETY EVALUATION

EQUIPMENT:

DESIGN,

TESTING

AND L-T-P-C:1-0-22

Course Coordinators: Dr. P. K. Mishra and R. K. Vishwakarma Types of mine safety equipment; Safety parameters in mine equipment; Legislations related to safety equipment; Principles of design of safety equipment; Different types of testing procedures; Testing and evaluation of safety equipment, machines, electrical cables, wire ropes and other accessories; Electrical hazards; Flame proof and intrinsically safe electrical equipment. ENG(CIMFR):2316

ADVANCED MINING METHODS

L-T-P-C:3-0-03

Course Coordinators: A. K. Ghosh and D. Kumbhakar Design of mine layouts for underground and surface mining; Design of coal and hard rock pillars; Advanced and special mining methods; Review of various experimental mining methods/procedures; Assessment of caving characteristics; performance and application of backfill; Coal bump and rock burst and their alleviation. Thick, thin and complex seams mining; Underground Coal Gasification and Coal Bed Methane; Choice of stoping method; Stope design; Production planning; Special underground excavations in metal mines; Consolidated and unconsolidated hydraulic & dry filling, paste filling stopes, preparation, transportation and filling operation; Solution Mining: in-situ leaching, chemical, bio-chemical and thermal leaching; Novel mining methods. ENG(CIMFR):2317

MECHANISATION AND AUTOMATION FOR MINE SAFETY

L-T-P-C:3-0-03

Course Coordinators: Dr. G. Banerjee and Dr. C. N. Ghosh Selection, procurement and replacement of mine equipment; State-of-the-art and future trends in mine mechanization and mine automation systems for both surface and underground mining; infrastructure required to support mine automation; Application of robotics and intelligent systems for safer mining; Potential economic, health and safety benefits of mine mechanisation and automation.

ENG(CIMFR):2318

ROCK BLASTING AND FRAGMENTATION

L-T-P-C:3-0-03

Course Coordinator: Dr. P. Pal Roy Advanced study of the theories of rock penetration; Explosives: Chemistry and physics of explosives; Properties of explosives; Explosive and blasting accessories; Initiation and priming systems; Bulk explosives; Heavy ANFO, ANFO with Sawdust & Rice-Husk; Criteria of explosive selection; Rock breakage by explosives: Theories, Rock breakage mechanism, Methods for prediction and assessment of fragmentation; Design of blasting rounds for surface and underground excavations; Special blasting techniques: Secondary breakage; Pre-split blasting; Smooth blasting; Cast blasting; Segregation blasting; Demolition blasting; Trench blasting and Induced caving by blasting. Environmental considerations: Control of Noise; Ground vibration; Air blast and Fly rock; Dust & Fumes. ENG(CIMFR):2319

INDUSTRIAL PHYSIOLOGY AND ERGONOMICS

L-T-P-C:3-0-03

Course Coordinators: A. K. Ghosh and Dr. Ranjan Kumar Anthropometry for design and body composition; Design principles – work station and tool design. Human information processing: man-machine-environment system. Environmental ergonomics and climatic factors: illumination, noise and vibration; Occupational health; Physiological factors. Fatigue-shift works. Control and display. Work posture. Selection of work force and training. Industrial and personal safety.

CSIR - Central Mechanical Engineering Research Institute The CSIR-Central Mechanical Engineering Research Institute (CSIR-CMERI) is the apex R&D institute for mechanical engineering. As a constituent member under the Council of Scientific & Industrial Research, the ambit of the Central Mechanical Engineering Research Institute (CMERI) – a premier establishment dedicated to research and development – extends over mechanical and allied engineering fields. In India, mechanical engineering technology has accounted for nearly half of the total technology imported. In terms of products, nearly one third of the value of total imports is for mechanical engineering equipment. In order to develop indigenously mechanical engineering technology for the industries so that R&D can play a key role in self-reliance, the Central Mechanical Engineering Research Institute at Durgapur, West Bengal was established in February 1958 with the specific task of development of mechanical engineering technology. Besides conducting frontline research in the varied areas related to mechanical engineering, the Institute dedicates it R&D efforts towards different mission mode programmes to disseminate appropriate technological solutions for poverty alleviation and societal improvement. CSIR - CMERI has a dedicated team well balanced in terms of youth and experience of highly qualified professionals and supporting staff spanning the various disciplines under mechanical engineering. Major Research Areas The major research areas are represented in the following schematic

In the new millennium, CSIR-CMERI is poised to expand its horizon of research activities so as to steer the country forward in the following cutting-edge and sunrise fields.

Robotics & Mechatronics

CSIR-CMERI is undertaking extensive research in the design and development of Autonomous Underwater & terrestrial Vehicles, All Terrain Robots, Subterranean Robots, etc. R&D issues cover mechanical design, attitude control, non-conventional propulsion and manoeuvre (bio-mimicry), actuator development, parallel/distributed computing, navigation and guidance, Collision avoidance, communication protocols, sensor fusion, etc. Micro Systems Technology, Surface Engineering & Tribology

Micro Systems Technology is associated with the technology of very small parts, actuators, devices and MEMS. Development of microfluidic chips affording precise control of very small quantities of liquid for analyzing gene expression and mutation identification in cells is being targeted. Research in Surface Engineering & Tribology has culminated in the development of µCNCmill - a five axis micro milling machine for efficient, cost effective and high resolution milling and drilling. Materials, Processes, Chemistry & Synthetic Biology

Materials science reposes on characterizing the atomic structure and phases in a particular material in relation to its desired properties and relative performance. CSIR-CMERI is working on the development of Dye-sensitized Solar Cells, Nano Composite Cutting Tool for high speed Machining and Platinization of Nafion towards the development of IPMC. Advanced Design, Manufacturing, Immersive Visualization

Design, manufacturing and product development at CSIR-CMERI is suitably aided by a comprehensive CAD-CAM environment supporting collaborative design through analysis of mechanisms, tolerances, interferences of designated parts, etc. Current R&D in metallurgy and foundry is focused on development of rheo die-casting system by integrating semi-solid slurry processing unit. Immersive Visualization affords rapid development of system concepts and analyzing for form, fit, function, logistics, human factors integration, and general feasibility analysis. Expertise in visualization is augmented with the induction of state-of-the-art facilities in Virtual Prototyping and Virtual Reality. Design Dynamics, Simulation and Analysis

Simulation and modeling for systems involving computational mechanics is a major module in the R&D agenda of CMERI. R&D is carried out across such diverse areas as FEA, FVA, FDA, Lattice-Boltzmann modeling, Electro-osmotic flow, flow induced vibration and high-speed aerodynamics. Current efforts are directed towards development of a general three-dimensional solver for simulating flow over aircraft wings. Thermal Engineering

Active research is carried out on fluid flow, heat transfer, combustion, gasification, fluidization, renewable energy, waste management, drying, etc. Additionally, research is carried out on solar-powered adsorptionbased space-cooling system, CFD simulation of fluidized bed hydrodynamics. Flow hydrodynamics is also being addressed through wind tunnel experimentation.

Cybernetics, Electronics & Embedded Systems, Drives & Control

Separate R&D groups dedicated to Cybernetics, Electronics & Embedded Systems and Drives & Control are working on electronics and embedded systems based product development. The design of electrical drive and control systems, electrical machines and power electronics products for different R&D and industrial requirements are being carried out.

Post Graduate Research Programme in Mechatronics Mechatronics is a design philosophy which encourages engineers to concurrently integrate precision mechanical engineering, digital and analog electronics, control theory and computer engineering in the design of “intelligent” products, systems and processes rather than engineering each set or requirements separately. The advantages of the Mechatronics approach to design are shorter design cycles, lower costs, and elegant solutions to design problems that cannot easily be solved by staying within the bounds of the traditional engineering disciplines. Mechatronics further relates to a multidisciplinary approach to product and manufacturing system design. The Post Graduate Research Programme in Mechatronics intends to acquaint students with the fundamentals of mechatronics through pedagogy on current theoretical and practical developments in this area. The programme traverses a wide range of applications that comprise robotics, product design, instrumentation, manufacturing methods, computer integration and process & device control, with specific emphasis on innovative engineering. The Two Year research Programme aims to provide in-depth exposure to the engineering concepts, scientific principles, research methodology and hands-on experience on advanced real-life R&D projects in different specializations related to Mechatronics Eligibility : BE/BTech in Mechanical, Electrical, Computer Science/Engg, Mechatronics, Electronics, ECE/ETC/EIE, Radio Physics & Electronics, Production, Manufacturing with minimum of 7.0 CGPA (or minimum of 70% marks).

Post Graduate Research Programme in Applied and Computational Mechanics Applied and Computational Mechanics is a unique programme highlighting analytical and computational methods for solving engineering problems studying phenomena governed by the principle of mechanics. The primary intention of this MTech Programme in Applied and Computational Mechanics is to train students in this multidisciplinary fields of research where they not only would learn basics of mechanics with associated mathematical and computational tools but also develop the capability of understanding and solving the physical problems of great industrial relevance. The programme discusses a wide range of subjects in the field of mathematics, solid, fluids and structural mechanics, numerical techniques like finite element methods computer applications. The participants would be provided in-depth exposure to various applied techniques of analytical, numerical and computational nature, scientific principles, research methodology and hands-on experience on advanced real-life R&D projects in different specializations such as stress analysis, nonlinear vibrations & chaos, computational fluid dynamics and heat transfer etc. Eligibility : BE/BTech in Mechanical Engineering , Aerospace Engineering and Civil Engineering with minimum of 7.0 CGPA (or minimum of 70% marks). Students undergoing the above programmes are expected to emerge properly equipped to confront

challenges across the industrial environment and academic research spectrum.

PhD Programme in Engineering Broad areas :

Who can apply :

i)

Robotics & Mechatronics

ii)

Micro System Technologies

iii)

Surface engineering and Tribology

iv)

Foundry

v)

Cybernetics and Machine Intelligence

vi)

Matrial Science

vii)

Solid Mechanics and Advanced Design

viii)

Fluid Mechanics and Heat transfer

MTech/ME in Mechanical, Electronics, Computer science, Electrical, Chemical or Aerospace Engineering

MTech & PhD COURSE DETAIL ENG(CMERI) 1-001

RESEARCH METHODOLOGY

L-T-P-C : 1-1-0-2

Course Coordinator: S. SenSharma General Practices followed in Research – literature and data management; Communication skills – writing and presentation; Intellectual property rights; Scientific ethics & Safety practices. ENG(CMERI) 1-002

MATHEMATICS FOR ENGINEERS

L-T-P-C : 3-0-0-3

Course Coordinator: Dr. Pradipta Basu-Mandal Linear Algebra: Linear independence, Orthogonality, Vector Spaces and their bases and dimensions, GramSchmidt method for orthogonal basis set, Orthogonal projections. Matrices, solution methods for linear simultaneous equations, Eigenvalue problem. Vector Analysis : Vector differentiation, Applications, Vector operators: Grad, Div and Curl. Vector integration & related Integral Theorems, Applications. Cylindrical and Spherical Co-ordinate Systems. Differential Equations: Linear ODEs of first and second orders, Linear second order equations, Applications. The Laplace Transform, Applications. Fourier Series and Applications. Partial differential equations of first and second orders. The Laplace and Wave Equations. ENG(CMERI) 1-381

INTRODUCTION TO MECHATRONICS SYSTEM

L-T-P-C : 3-0-0-3

Course Coordinators: Dr. Ranjit Ray & S.N. Shome Overview: What is Mechatronics? Instrumentation and Control System. Sensors & Transducers: Physical Principles & Basic mechanisms in sensor systems, performance characteristics, Different type of Sensors and transducers based on principles – Position and Speed Measurement, Stress and Strain Measurement, Temperature Measurement, Vibration and Acceleration Measurement; Actuators: Electromagnetic Principles, Motors – Electric, Hydraulics & Pneumatics; Mathematical Modeling: State space representation, Model Linearization, Sate model from linear graphs, Bond graphs, Modeling Electromechanical Systems. Structures and Materials, Modeling of Mechanical Systems for Mechatronics Applications, Fluid Power, Using MATLAB SIMULINK for modeling and simulation Mechatronics systems; Interfacing & Virtual Instrumentation.. ENG(CMERI) 1-382

ADVANCED CONTROL SYSTEM

L-T-P-C : 3-0-0-3

Course Coordinators: S. Nandy Overview: What is Mechatronics? Instrumentation and Control System. Sensors & Transducers: Physical Principles & Basic mechanisms in sensor systems, performance characteristics, Different type of Sensors and transducers based on principles – Position and Speed Measurement, Stress and Strain Measurement, Temperature Measurement, Vibration and Acceleration Measurement; Actuators: Electromagnetic Principles, Motors – Electric, Hydraulics & Pneumatics; Mathematical Modeling: State space representation, Model Linearization, Sate model from linear graphs, Bond graphs, Modeling Electromechanical Systems. Structures and Materials, Modeling of Mechanical Systems for

Mechatronics Applications, Fluid Power, Using MATLAB SIMULINK for modeling and simulation Mechatronics systems; Interfacing & Virtual Instrumentation. ENG(CMERI) 1-383

CAD & COMPUTER GRAPHICS

L-T-P-C : 3-0-1-3

Course Coordinator: Avik Chatterjee Genesis of CAD, Simulation and Visualization, Concepts of CAE and Virtual Prototyping; Geometric Object Modeling – Analytical Representation of Curves & Surfaces, Various Curves and Surfaces (BSpline, Bezier, NURBS), Intersection calculations, Assembly Modeling Techniques; Computer Graphics: Linear algebra, Screen coordinates, Window coordinates, Graphics library, Rendering pipeline architecture, Homogeneous coordinates & Transformation Matrices, Quaternion, Projection matrices, Types of buffers, Display Interpolation techniques, Lightning, Wireframe, Shading models, Texture mapping, Ray casting, Ray tracing, Normal vectors, Evaluators & NURBS, Modeling of sculpture surface, selection and feedback, Concepts of scenes and scene graphics, Hierarchical Modeling Concepts, Kinematic Simulation of an Hierarchical model, Stereo Visualization. ENG(CMERI) 1-384

ELECTRICAL AND ELECTRONIC CIRCUITS & DEVICES

L-T-P-C : 3-0-1-3

Course Coordinators: Ms. Uma Datta & J. Roy Choudhury Electric Circuits and Components Network Theorems: Thevenin, Norton, Superposition, Maximum Power Transfer. Circuit Analysis, Transformer, Impedance Matching, Grounding and Electrical Interference, Electrical Safety. Semiconductor Electronics: Diodes and its’ application; Operation, characteristics : Three terminal devices –BJT, JFET, MOSFET; Four terminal devices- SCR, Diac, Triac; Amplifiers using BJT, FET; Operational amplifiers Modern devices: CMOS, MESFET, MODFET, HBT. Computing: Number, system and code conversion, Logic gates, Boolean algebra, Combinational / Sequential Logic circuits – Latch, RS-, JK-, T-, D-, Flip flops, Buffer Register, Counters, Shift registers. Decoder, Encoder, MUX, DMUX, RAM, ROM, PROM, EPROM, EEPROM, Programmable logic devices. ENG(CMERI) 1-385

MACHINES & MECHANISMS

L-T-P-C : 3-0-0-3

Course Coordinators: P.S. Banerjee & Dr. R. Sen Rotation and Plane motion of a rigid body. Kinematic Pairs, Chains, Diagrams. Four Link Planar Mechanisms and their Inversions. Grubler’s criterion and Grashof’s criterion. Analysis of planar mechanisms – Graphical and Analytical methods Synthesis of planar mechanisms – Motion, Path and Function generation problems - Graphical and Analytical approaches Introduction to Machine Elements – Cams, Gears, Brakes, Clutches etc Cams – classification of cams and followers, nomenclature, description and analysis of follower motion, pressure angle. Determination of basic dimensions, Synthesis of cam profiles – Graphical and Analytical methods. Gears – terminology, fundamental law of gearing, involute profile. Interference and undercutting, Simple, Compound and Epicyclic gear trains.

ENG(CMERI) 1-386

ROBOTICS

L-T-P-C : 3-0-1-3

Course Coordinators: Dr. Soumen Sen & S.N. Shome Robotics introduction; Classification and Components; Rigid body transformation in R3; Homogeneous representation; Denavit-Hertenberg representation; Forward and Inverse kinematics; Redundant and Non-redundant robots; Differential kinematics, velocities, and their transformations; Geometric and analytical Jacobians; Manipulability, Isotropy and Workspace analysis; Manipulator statics; Velocity-force duality; Recursive computation of velocities and accelerations; Manipulator dynamics -Newton-Euler and Euler-Lagrange; Equation of motion; Path planning in joint and task space; Obstacle avoidance and optimal planning; Review of robot control methods; Optimization in robotics; Human-robot interaction; joint and link flexibilities; Walking machines and Exoskeletons; Robot hand and multifingered grasp, manipulation and control; Tendon driven manipulator. ENG(CMERI) 1-387

MICROCONTROLLERS & EMBEDDED SYSTEM DESIGN

L-T-P-C : 3-0-1-3

Course Coordinators: J. Roy Chaudhuri & Shikha Introduction to embedded systems and architecture, System design using specification and modeling tools Overview of embedded computing platforms; Microprocessors, Microcontrollers, DSP’s and SoC’s, Hardware – Software design and partitioning Design issues, consideration and trade–offs: Performance memory, power, timing, cost, and development time. Memory hierarchy, System Interfaces and Communication with peripheral units, timers counters, Introduction to Real-time system and Real-time Scheduling Real – time software development: High level languages and Programming issues, Systems performance: Networked embedded systems Future Trends, Applications, Tutorial & Laboratory . ENG(CMERI) 1-388

DIGITAL SIGNAL PROCESSING & APPLICATIONS

L-T-P-C : 3-0-1-3

Course Coordinators: J. Roy Choudhury & SRK Vadali Elements of Analog and Digital Signal Processing, Advantages of Digital over Analog, Sampling Theorem. Discrete Time Signals & Systems – Classification, Analysis of LT Systems, of LTI system Response to Arbitrary Inputs, Causality & Stability; Correlation, Convolution, Finite & Infinite Impulse Response, Recursive & NonRecursive Systems, Difference Equations. Z-Transform – Definition, Properties; Inverse-Z and Analysis in Z-domain. Fourier Analysis – Continuous & Discrete-Time Fourier Series, Power Density Spectrum, Fourier Transform, Frequency-Domain Characteristics of LTI Systems, DFT & Properties, Linear Filtering Using DFT, Frequency Analysis Using DFT, Understanding FFT. Digital Filter Design – Characteristics & Design of Filters. Future Trends, Applications, Tutorial & Hands-on ENG(CMERI) 1-389

ADVANCED MECHANICS OF SOLIDS

Course Coordinators: Dr. Somenath Mukherjee & Dr. Pradipta Basu-Mandal Stress; Stress tensor, stress transformation, principal stresses. Equilibrium. Strain; Linear strain components, Compatibility. Constitutive Relations; Isotropic and orthotropic materials, Failure Theories.

L-T-P-C : 3-0-0-3

Two dimensional elasticity; Mohr’s Circle. Polar co-ordinates. Airy’s Stress Function for simple systems. Stress concentration factors. Stresses in pressure vessels and rotating discs. Torsion of bars of various sections. Beam bending; Deflections. Three Moment equation. Unsymmetric bending, bending stress and shear and shear center. Variational principles; Equilibrium- Virtual work and the Principle of Stationary Potential Energy, CompatibilityPrinciple of Stationary Complementary Energy, Castigliano’s Theorems, Applications. Elastic Stability; Euler’s Bucking Load for columns. Energy methods, Stability of simple frames. ENG(CMERI) 1-390

ADVANCED MECHANICS OF FLUIDS

L-T-P-C : 3-0-0-3

Course Coordinators: Dr. Sudipta De & Dr. Satya Prakash Equations of fluid mechanics, Exact solutions of Navier-Stokes equations, Boundary layers, Approximate methods for solving boundary layer equations, Boundary layer control, Axisymmetric and three-dimensional boundary layers, Unsteady boundary layers, Stability Analysis, Transitional flows. ENG(CMERI) 1-391

MECHANICAL VIBRATIONS

L-T-P-C : 3-0-0-3

Course Coordinators: Dr. Pranab Samanta & Dr. Swarup Kumar Laha Free vibrations and response of single-degree-of-freedom systems to harmonic, periodic and general excitations, Energy dissipation and damping, Duhamel’s Convolution Integral for response to general time varying excitation. Multi-Degree-of-Freedom Systems; Lagrange’s Equations. Free Vibration- The Eigenvalue Problem, Orthogonality of Modal Vectors, Dynamic response by Modal Analysis. Rayleigh’s Quotient. Distributed Systems; Exact solutions of free and forced vibrations of bars and beams (axial, torsional and bending). Modal shapes and natural frequencies of continuous systems, Systems with lumped masses, Rayleigh’s Principle Approximate Methods; Transfer Matrix Methods, Holzer’s Method for Torsional Vibration, Myklestad’s Method for bending vibration, Dunkerley’s Method, Modal Superposition Methods. ENG(CMERI) 1-392

COMPUTER LAB-I

L-T-P-C : 1-1-2-3

Course Coordinators: Dr. Surendra Kumar & Dr. Swarup Kumar Laha The Solution of Nonlinear Equations: Iterative Methods, Fixed-Point Iteration, Newton-Raphson and Secant Methods, Polynomial Equations Having Real Roots. Matrices and System of Linear Equations: The Solution of Linear Systems by Elimination, Pivoting, Triangular Factorization, Eigenvalue Problem. Approximation: Uniform Approximation by Polynomials, Data Fitting, Orthogonal Polynomials, Least-Squares Approximation by Polynomials. Differentiation and Integration: Numerical Differentiation, Numerical Integration and Associated Basic Rules, Gaussian Rules. The Solution of Differential Equations: Simple Difference Equations, Numerical Integration by Taylor Series, Runge-Kutta Methods, Multistep Formulae, PredictorCorrector Methods. Computer programming and code development of the algorithms taught in class.

ENG(CMERI) 1-393

FINITE ELEMENT METHODS

L-T-P-C : 3-0-0-3

Course Coordinators: Dr. Somenath Mukherjee & Dr. Pradipta Basu-Mandal Matrix methods review; Stationary Principles, Rayleigh-Ritz and Hellinger-Reissner Methods. Virtual Work, Governing Equations, Weighted Residual (Galerkin) Method and Weak Forms. Formulations of one-dimensional elements (axial bar, the Euler beam) using Direct and Variational Methods. Solutions to simple truss and frame problems. Interpolation, C0 and C1 elements. Convergence requirements. Isoparametric one and two-dimensional elements; Linear and Quadratic Timoshenko beam elements; shear locking. Linear 2D plane stress /plane strain element; parasitic shear. Reduced integration. Elementary theory of plates and plate elements; Mindlin and Kirchhoff element formulations, Concepts of locking. Full, reduced and selective integration techniques. Axisymmetric elements. The Best-fit paradigm of FEA. ENG(CMERI) 1-394

ANALYSIS AND SYNTHESIS OF MECHANISMS

L-T-P-C : 3-0-0-3

Course Coordinators: P S Banerjee & S N Shome Particle and Rigid Body Dynamics – Kinematics and Kinetics. Rigid body rotation, Velocity and Acceleration analysis using Instantaneous Centre (IC) of velocity, Corioli’s component of acceleration, Plane motion of a rigid body. Kinematic Pairs, Kinematic Chains, Kinematic Diagrams, Four Link Planar Mechanisms and their Inversions Kutzbach and Grubler’s criterion, Grashof’s criterion, Analysis of plane mechanisms – Graphical and Analytical methods Dimensional synthesis of mechanism; Motion, Path and Function generation, precision point approach, Chebyshev spacing, three position synthesis, graphical and analytical approaches for four link mechanisms. Development of simple algorithms and computer programs for solving typical problems on analysis and synthesis of mechanisms. ENG(CMERI) 1-395

COMPUTATIONAL FLUID FLOW & HEAT TRANSFER

L-T-P-C : 3-0-0-3

Course Coordinators: Prof. Gautam Biswas, Bittagopal Mondal & Dipankar Chatterjee Discretisation procedure in Finite-difference and Finite-volume. Navier-Stokes, Energy equations. Staggered rectilinear grids. Explicit methods : MAC, SMAC. Implicit Methods, SIMPLE and SIMPLER. Matrix methods, conjugate gradient method, strongly Implicit Procedure. Grid-Generation:Algebraic, Transfinite, Poisson equation methods. Finite-difference Navier-Stokes solution on nonorthogonal grids, transformation. Collocated grids. Finite-volume methods on non-orthogonal grids. Turbulence modelling, k-e modeling. ENG(CMERI) 1-396

COMPUTER LAB - II

L-T-P-C : 0-0-4-2

Course Coordinators: Dr. Surendra Kumar, Avik Chatterjee and Dr. Satya Prakash Singh Problem solving utilising application software like ANSYS, ADAMS, FLUENT etc.

ENG(CMERI) 2-381

INTRODUCTION TO COMPUTER VISION

L-T-P-C : 3-0-1-3

Course Coordinators: Dr. S. Majumdar Fundamentals of Computer Vision: Role of vision to achieve simple goals i.e. high level capabilities of vision using cognitive processes, geometric models and low level capability for object perception, representation of images. Computer Vision Research and Application on image formation, camera model and camera calibration, properties of projection, interaction of light and its modeling, perspective modeling, homogeneous coordinate, lens equation, types of image digitizers and image digitizing components. Feature Extraction, filtering and edge detection, fourier transform, texture primitives and texture as a pattern recognition problem, wavelets and multiresolution processing including image pyramids, subband coding, Harr Transform; multiresolution expansions and colour processing. Tutorial on Matlab platform & Project ENG(CMERI) 2-382

ROBOTICS AND MACHINE INTELLIGENCE

L-T-P-C : 3-0-1-3

Course Coordinators: J. Roy Choudhury Artificial Intelligence, Computational Intelligence, Various Machine Learning Algorithms ,Pattern Reorganization, Computer Vision, Fuzzy Expert System, Fuzzy Automata. Fundamentals Of Robotics & Automation., Intelligent Robots, Control Systems and Components . Robot Motion Analysis and Control,Robot End Effectors,tactile and vision sensors in robotics Cognitive system for Human machine interaction. Future Trends, Applications, Tutorial & Laboratory. ENG(CMERI) 2-383

INTRODUCTION TO NAVIGATION & DATA FUSION

L-T-P-C : 3-0-1-3

Course Coordinators: Dr. S. Majumdar Sensors, Sensing, Model of Sensors & Process uncertainties Introduction to estimation, estimation methods & relation between different estimators State space modeling, LTI Systems & Kalman Filter & Extended Kalman Filter Other Navigation Filters including Bayesian Filters, Information Filters, Particle Filter etc. Various Sensors used in Robotics: Accelerometer, Gyro, Compass, Encoder, Laser, Ultrasonic Sensor, Camera, Sonar, InfraRed Sensor, Tactile Sensor etc. Multisensor Data Fusion Fundamentals; INS, GPS Aided Navigation & Data Fusion Future Trends, Applications, Tutorial & Laboratory ENG(CMERI) 2-384

MICRO SYSTEMS TECHNOLOGIES

L-T-P-C : 3-0-1-3

Course Coordinators: Dr. Nagahanumaiah Introduction: precision engineering; multi-scale product manufacturing paradigms. Micro- Nano Manufacturing: MEMS foundry processes; micro-mechanical processes; regenerative techniques. Process Modelling: material removal mechanisms; FEA and molecular dynamics based simulations. Design of Micro Machines: sources of error; error mapping; precision drives and controls. Sensors for Precision Manufacturing: sensor systems for process monitoring, multi sensor approaches, signal processing and machine vision systems. Precision

Metrology: definitions; laser interferometer; AFM; SEM; TEM. Micro Factory Concepts: micro assembly, composite molding, micro robotics, geometric analysis, decision systems, process planning and micro factory layout designs. Micro-nano systems engineering: module applications; micro-nano scale product design; case studies for biomedical, sensors, and nano technology applications. Tutorial and Laboratory practices. ENG(CMERI) 2-385

ADVANCED MATERIALS

L-T-P-C : 3-0-1-3

Course Coordinators: A. Chaudhuri Basics: Mechanics of materials, mechanical properties, dislocation theory, mechanical testing methods, creep and relaxation behaviour of common engineering materials Advanced materials: Polymers, conductive polymers, ceramics, composites, nano-composites, smart materials, high temperature materials, bearing materials, materials for sensors and actuators Material characterization: Optical and X-ray spectroscopy, diffraction methods (X-ray diffraction, Crystallographic texture measurements, electron microscopy (SEM, TEM, EBSD, etc.), Atomic probe micro analysis (AFM), Thermo gravity analysis Future Trends, Applications, Tutorial & Laboratory ENG(CMERI) 2-386

OPTIMAL CONTROL

L-T-P-C : 3-0-1-3

Course Coordinators: S. Nandy Introduction: Problem formulation, Mathematical model, Physical constraints, Form of optimal control, Performance measures, Static optimization techniques. Dynamic Programming and related topics: Introduction, Principle of optimality, Hamilton-Jacobi-Bellman equation, Continuous linear regulator problems, Pontryagin’s maximum principle, Control with constraints, Time optimal control, Optimal tracking control problem. Variational Approaches: Calculus of variations, Fundamental concepts, Functionals, Euler’s equation, Lagrangian, Variational approach, Optimal control law, Necessary conditions, Linear regulator & tracking problems, Multi-variable optimization problem, Linear Quadratic Regulator. Optimization Methods: Minimum time problems, Minimum control-effort problems, Kalman Filter, Non-linear system optimization, Gradient optimization techniques, Steepest ascent and decent method, Rosenbrock’s conjugate gradient method, David-Fletcher-Power method. ENG(CMERI) 2-387

PRECISION MACHINE DESIGN

L-T-P-C : 3-0-1-3

Course Coordinators: Dr. N.C. Murmu Economics, project management and design philosophy, principles of accuracy, repeatability and resolution; error budgeting. Flexure design - linear and non-linear deflection, stiffness and strength, displacement vs force loads, material considerations, fatigue failure and its prevention. Bearings: rolling contact bearings, flexural bearings, gas bearings and magnetic bearings and design engineering surfaces. System design - manufacturing considerations, materials, structural design, joint design, support system and kinematic coupling design, sensors, actuators and transmissions and system integration driven by functional requirements and operating physics. Mini Project – application of theory and heuristics to the design of precision mechanical systems. Tutorial & Mini Project.

ENG(CMERI) 2-388

NUMERICAL METHODS & COMPUTER PROGRAMMING

L-T-P-C : 3-0-1-3

Course Coordinators: Dr. Partha Bhattacharya Introduction, finite floating point arithmetic, catastrophic cancellation, chopping and rounding errors; Solution of nonlinear equations; bisection, , Newton's & Muller's method, fixed point iteration; Numerical optimization, Golden section search, Newton's method optimization; linear algebraic equations; forward Gaussian elimination, pivoting, scaling, back substitution, LU-decomposition, norms and errors, condition numbers, iterations, Newton's method for systems, computer implementation; Interpolation- Lagrange, Newton & inverse ; Numerical Integration; finite differences, Newton cotes, trapezoidal, Simpson's rule, extrapolation, Gaussian quadrature; Numerical solution of ODE; Euler's method, Runge-Kutta method, multi-step methods, predictorcorrector methods, rates of convergence, global errors, algebraic and shooting methods, boundary value problems, computer implementation. ENG(CMERI) 2-389

ELECTRO-MECHANICAL SYSTEMS DESIGN

L-T-P-C : 3-0-1-3

Course Coordinators: Dr. Nagahanumaiah Introduction: Electro-Mechanical systems and applications: design and analysis of micro-nano positioning systems; ultra precision screw drives; Dual drive positioning systems; flexural joints; design and kinematics analysis of parallel kinematics platforms. High Speed Power Sstems: Distributed loads in electro-mechanical motion drives; Design and dynamic analysis of high speed spindle. Analysis and Synthesis of Fluid Mechanical Systems: hydraulic actuators, micro fluidic flow problems, solving micro pump system design. Instrumentation: sensors, actuators, encoders, servo mechanisms, laser interferometery and other position calibration techniques. Future Trends: Tutorial & Laboratory practices. ENG(CMERI) 2-390

ANALYTICAL MECHANICS

L-T-P-C : 3-0-0-3

Course Coordinators: Dr. Somenath Mukherjee Optimum Path: Fermat’s Principle, Brachistochrone Problem. Calculus of Variation in Mechanics for Conservative Systems. Degrees of Freedom and the Configuration Space. The Concept of Functionals and their Variations. Virtual work, the varied path. Hamilton’s Principle of Stationary Action, Lagrange’s Equations of Motion. Applications of Lagrange’s Equations: Equations of motion of multi-degree of freedom systems. Vibrations of discrete systems (of lumped masses) and continuous elastic systems. Lagrange Multipliers for Constrained Systems. Applications. Hamiltonian Mechanics: The Legendre Transformations, Hamilton’s Cannonical Equations of Motion, Applications. Accelerating /rotating reference frames. Dynamics of rotation of rigid bodies. Central force systems; Motion of satellites. ENG(CMERI) 2-391

FINITE ELEMENT METHODS FOR FLUID DYNAMICS

L-T-P-C : 3-0-1-3

Course Coordinators: Dr. Satya Prakash Singh Fundamental concepts; strong form, weak form, Galerkin approximation; matrix equations, element and global point of view; numerical integration – Gaussian quadrature; temporal discretization - generalized trapezoidal rule; compressible and incompressible flows; implementation of the methods; issues related to high performance computing.

ENG(CMERI) 2-392

NONLINEAR DYNAMICS & CHAOS

L-T-P-C : 3-0-0-3

Course Coordinators: Dr. Pradipta Basu-Mandal One-Dimensional Flows; Flows on the line & circle: Fixed Points and Stability, Linear Stability Analysis: UniformNonuniform Oscillator, Overdamped Pendulum. Two-Dimensional Flows; Linear Systems with classifications, Phase plane; Phase Portraits, Fixed points and Linearization, Conservative Systems, Reversible Systems. Limit Cycles, Poincare-Bendixson Theorem, Relaxation Oscillations, Weakly Nonlinear Oscillations. Bifurcations; Saddlenode, Transcritical, Pitchfork and Hopf Bifurcations. One-Dimensional Maps; Stability of Fixed Points, Periodic Points, Poincare Map, Logistic Map, Dependence on Initial Conditions. Two-Dimensional Maps; Sinks, Sources and Saddles, Linear Maps, Coordinate Changes, Nonlinear Maps and the Jacobian Matrix, Stable and Unstable Manifolds. Chaos in Two-Dimensional Maps; Lyapunov Exponents: Numerical Calculation. Chaos in Differential Equations; Lorenz Attractor, Lyapunov Exponents for Flows. ENG(CMERI) 2-393

MECHANICS OF COMPOSITE MATERIALS

L-T-P-C : 3-0-0-3

Course Coordinators: Dr. Surendra Kumar Introduction to Composite Materials, Classification of composites; Fibres and matrices; Manufacturing, mechanical properties and applications of composites. Stress-strain relationships for a unidirectional/bidirectional lamina; strengths, thermal and moisture expansion coefficients. Determination of physical and engineering properties of a unidirectional lamina from the individual properties of the fiber and the matrix, fiber volume fraction, and fiber packing. Determination of the elastic stiffnesses and mechanical loads on laminate based on the values of individual laminae and the stacking sequence. Failure Criteria for a unidirectional composite lamina and a laminate; Design of laminated composite and other issues. ENG(CMERI) 2-394

ROTOR DYNAMICS

L-T-P-C : 3-1-0-4

Course Coordinators: Tapan Kr. Paul & Dr. S.K. Laha Introduction to rotor dynamics. Flexural vibration & Torsional vibration. Critical speeds of rotors and response to imbalance. Factors affecting them such as gyroscopic action, internal damping, fluid film bearing. Methods for analysis such as Transfer Matrix, FEM etc. Bearing and Seals rotor dynamics. Stability of rotor systems. Balancing of rotors. Concepts of condition monitoring and Signature analysis. ENG(CMERI) 2-395

COMPRESSIBLE FLOW

L-T-P-C : 3-1-0-4

Course Coordinators: Dr. Sudipta De and Dr. T. Murugan Brief review of fluid mechanics and thermodynamics, Flow regimes, Governing equations of compressible fluid flow, 1-D inviscid flows, Flow through nozzles and intakes, Mathematical theory of characteristics, Acoustic waves, Normal and oblique shock waves, Unsteady wave motion, The shock tube and moving shock waves, shock tube relations, Flow past wedge and aerofoil, Shock- Boundary layer interaction, Numerical techniques for compressible flows.

ENG(CMERI) 2-396

F LOW THROUGH TURBO MACHINES

L-T-P-C : 3-1-0-4

Course Coordinators: Dr. L.G. Das Basic thermodynamics and fluid mechanics of turbo machines, dimension less performance characteristics, cascade theory, concept of circulation, lift and drag, conformal transformation developing blade geometry, isentropic flow analysis, axial flow turbine, radial flow turbine, selection of degree of reaction and effect on efficiency, centrifugal compressor and pump, compressor surging,3-D through flow analysis of the combined stator and rotor, performance prediction, cause & effect of secondary flow on the performance, effect of turbo machine geometry and operation characteristics on the performance, off-design performance analysis. ENG(CMERI) 2-397

FLUIDIZED BED DRYING

L-T-P-C : 3-1-0-4

Course Coordinators: Dr. P.K. Chatterjee Principle of fluidization, advantages & limitations, Thermal physical properties/Geldart classification, Heat transfer in fludizied bed drying, Basic principles of drying/drying curves, effects of operating parameters, batch/continuous/mechanically assisted fluidized bed dryer, Spouted bed dryer, Diffusion/kinetic/1-2-3 phase models and design procedures. ENG(CMERI) 2-398

FLUIDIZED BED COMBUSTION & GASIFICATION

L-T-P-C : 3-1-0-4

Course Coordinators: Dr. Malay Karmarkar and Chanchal Kr. Loha Introduction - Fluidized bed equipment, Features of fluidized bed; Gasification and combustion - Theory, Effect of operating parameters and feed properties. Gas cleaning, Design consideration, Application; Hydrodynamics – Regimes of fluidization, Bubbling and fast fluidized beds, gas-solid flow structure, gas-solid mixing, Gas-solid separators; Heat and mass transfer between fluid and solid; Modeling – equilibrium modeling, kinetic modeling, CFD modeling in bubbling and circulating fluidized systems. ENG(CMERI) 2-399

THERMODYNAMICS

L-T-P-C : 3-1-0-4

Course Coordinators: Biplab Chowdhury State of Equilibrium, First Law of Thermodynamics, Second Law and Entropy, Availability and Exergy, Postulatory (Gibbsian)Thermodynamics, General Thermodynamic Relationships, Equations of State, Thermodynamic Properties of Pure Fluids and Mixtures, Stability, Chemically Reacting Systems, Reaction Direction and Chemical Equilibrium, Availability Analysis for Reacting Systems, Chemical Kinetics ENG(CMERI) 2-400

PRINCIPLES OF CASTING SOLIDIFICATION

L-T-P-C : 3-1-0-4

Course Coordinators: Dr. Sudip Kr. Samanta Thermodynamics of solidification; Single phase and alloy solidification; Cellular and Dendritic growth; Mathematical analysis of redistribution of solute during solidification; mechanism of dendritic arm fragmentation, dendritic to equiaxed globular grain transformation, alloying effect on solidification; Solidification of metallic composite materials; diffusion kinetics; Fick's Law of diffusion, diffusion and phase transformation; Multiphase flow Modelling of alloy solidification, Case studies.

ENG(CMERI) 2-401

CONVECTIVE HEAT & MASS TRANSFER

L-T-P-C : 3-1-0-4

Course Coordinators: Prof. Gautam Biswas and Dr. T. Murugan Conservation equations, boundary layers, free convection, forced convection. Heat transfer in laminar and turbulent, internal as well as external flows, mixed convection. Combined convection and radiation. Boiling and Condensation. Molecular diffusion in fluids, mass transfer coefficient. Simultaneous heat and mass transfer; Applications. ENG(CMERI) 2-402

TURBULENCE

L-T-P-C : 3-1-0-4

Course Coordinators: Prof. Gautam Biswas and Dr. T. Murugan Origin of turbulence, Scales of turbulent motion, Correlation Functions, Kolmogorov Hypothesis and Probability Density Function; Statistical description of turbulence, Experimental techniques, Classical Idealization of Turbulent Flows; Vorticity Dynamics; Dynamics of Turbulent Kinetic Energy and Important Scaling Relations; Mean flow equations and Reynolds stresses; Closure problem; Free and wall bounded shear flows, Space-time correlations, Turbulent flows in pipes and channels, Laws of wall and fully developed turbulence; Spectral dynamics, Modeling Concepts; Direct and Large Eddy Simulation; ENG(CMERI) 2-403

STATISTICAL METHODS FOR ENGINEERS

L-T-P-C : 3-1-1-4

Course Coordinators: Dr. Partha Bhattacharya Statistical Computing: Graphical representation, Frequency distribution, Measures of central tendency and dispersion, Random variable - it’s expectation and variance, Probability models – Binomial-Poission-normal. Bivariate Frequency Distributions. Scatter Diagram, Product Moment, Correlation coefficient with properties, regression lines, correlation index and ratio, Spearman rank correlation. Multiple linear regression, multiple correlation, partial correlation. Random sampling, expectations and standard error of sampling mean (without derivation), expectation and standard error of sampling proportions. Point of estimation of parameters, Maximum likelihood estimation, interval estimate of parameters, test of significance based on t, F and CHI square distribution. Large sample tests, Tests based on Pearsonian frequency CHI-square. ENG(CMERI) 2-404

ADVANCED ELECTRICAL DRIVES

L-T-P-C : 3-1-0-4

Course Coordinators: S. Sen Sharma A.C. phase control circuits: Single phase AC voltage regulators and cycloconverters; Power Inverters: Single phase bridge, three phase bridge and PWM inverters Drives: Selection. Control and stability of electric drives. D.C. motor controllers: Armature voltage control of separately exited DC shunts Motor; single quadrant, two quadrant and four-quadrant operation; field current control, micro controller based control circuit for motor control; A.C motor controllers: Squirrel cage induction motor control, control-stator voltage control, V/F control, control of wound rotor motor, slip power recovery D.C and AC servo motor controller; stepper motor controller; Brushless DC motor controllers; Drives for Electric and hybrid Vehicles.

ENG(CMERI) 2-405

INSTRUMENTATION & INDUSTRIAL CONTROL

L-T-P-C : 3-0-2-4

Course Coordinators: Shikha Measurement systems: General concepts, Performance terms, static and dynamic characteristics, system transfer function, system accuracy, sources of error. Sensors & Transducers: Transducer Fundamentals, resistive, inductive, capacitive, piezoelectric, optoelectronic, pressure, strain, torque, speed, chemical, temperature. Smart sensors & Intelligent Instrumentation: Smart sensors and its categories; intelligent instrumentation systems. Programmable Logic Controllers: Construction Types, Hardware, Programming and Applications. Industrial Communication in Process Control: Smart transmitters, Hardware and Software protocols, RS232, Modbus, GPIB, HART, FF and other IEEE Standards. Virtual Instrumentation: Graphical programming, loops and charts, arrays, clusters and graphs, case and sequence structures, advantages of VI. Labview applications. ENG(CMERI) 3-001

ADVANCED SELF STUDY

L-T-P-C : 3-1-0-4

Course Coordinators: Concerned Faculties Specialised advanced courses would be offered in consultation with the thesis supervisors and Doctoral Advisory Committee (DAC). ENG(CMERI) 3-002

PROJECT PROPOSAL - I

L-T-P-C : 0-1-2-2

Course Coordinators: Concerned Thesis supervisor(s) Formulation of a project proposal in specified format in a holistic manner preferably candidate’s own research work suitable for submission to appropriate funding agencies. ENG(CMERI) 3-003

PROJECT PROPOSAL - II

L-T-P-C : 0-1-2-2

Course Coordinators: Concerned Thesis supervisor(s) Formulation of a complete project proposal in specified format on the related subareas of candidate’s own research work. ENG(CMERI) 3-004

CSIR-800 SOCIETAL PROGRAMME

L-T-P-C : 0-0-8-4

Course Coordinators: Concerned Faculties The students have to undertake a project in rural areas for 6-8 weeks in the line with CSIR-800 programme which is primarily prepared at empowering 800 million Indians by way of S&T inventions. The theme for the project may be chosen from CSIR-800 documents and as per expertise available in the laboratory. Students will select the topics in consultation with Doctoral Advisory Committee (DAC). ENG(CMERI) 3-381

ADVANCED COMPUTER ORGANIZATION & ARCHITECTURE

L-T-P-C : 3-1-1-4

Course Coordinators: Dr. Partha Bhattacharya Introduction of different Computer generations. Design Methodology: Introduction, CPU, registers, BUS, memory.

Processor Design: Processor organization, instruction sets, fixed point arithmetic. Control Design: Instruction sequencing, Hardware control, micro-programmed control, minimizing microinstruction size. Memory Organization: Memory technology, Virtual memory, high speed memories. I/O Systems: Programmed I/O, DMA and interrupt, I/O processor. Computer Network: Communication Protocols, Circuit Switch, Message Switch and Packed Switch, CDMA. LAN, WAN etc. communication devices, Cellular Network. Parallel processors, pipeline structures, Vector Processor etc. Pipelined instruction units, Arithmetic pipelined design, Multifunction and array pipelines, designing pipelined processor, Dynamic pipelined and re-configurability, Multiple vector task dispatching. ENG(CMERI) 3-382

APPLIED SOFTCOMPUTING

L-T-P-C : 3-1-1-4

Course Coordinators: Dr. Arup Nandi Artificial neural network (ANN), Supervised and unsupervised learning of ANN, fuzzy logic, fuzzy membership function distributions, fuzzy logic rules, fuzzy and neuro-fuzzy inference systems, Genetic-fuzzy system, rough sets, The Hopfield Network; Support Vector Machines; Evolutionary algorithms, differential evolution, simulated Annealing, antcolony optimisation, particle swarm optimisation, hybrid-system, engineering applications of modeling and optimisation. ENG(CMERI) 3-383

OPTIMIZATION TECHNIQUES IN ENGINEERING

L-T-P-C : 3-1-1-4

Course Coordinators: Dr. Arup Nandi Classical optimization methods, unconstrained minimization; Univariate, conjugate direction, gradient and variable metric methods, constrained minimization, Feasible direction and projections. Integer and Geometric programming, multi-objective optimization, genetic algorithms (GAs), multi-objective GA, simulated annealing techniques, engineering applications. ENG(CMERI) 3-384

LOW POWERED EMBEDDED SYSTEM DESIGN

L-T-P-C : 3-1-1-4

Course Coordinators: J. Roy Choudhury Hardware-software co-design, FSM and Timed automata, Modeling and design, Poware aware scheduling techniques, SDL, SpecChart etc. Architectural synthesis for DSP, Verification of digital systems - finite state automata, ù-automata, FSM; Sampling theorem and digital signal sequence, Frequency response and FIR,DFT and FFT, Tools for DSP Analysis and design, Decimation in time and frequency, FFT algorithms, discrete cosine transform; DSP ASIC Design, Configurable Logic, Design Methodology of power aware systems, VLSI Implementation of DSP Processors, Embedded systems Architecture and assembly instruction set; Adaptive Filters, The LMS Algorithm, Adaptive Lattice Ladder Filters, Recursive Least Squares Lattice Ladder Algorithms. ENG(CMERI) 3-385

COMPUTER AIDED METROLOGY AND MACHINE VISION

L-T-P-C : 3-1-1-4

Course Coordinators: Dr. R. Sen Precision, accuracy, repeatability, reproducibility, contact and noncontact measurements, challenges of temperature, probes and environment, uncertainty of measurements. Co-ordinate Measuring Machine: construction, process, probing and software, error compensation and alignment, prismatic component inspection, profile and surface measurement. Application of Laser interferometer: Basics, flatness testing, surface contour test, scales and gratings, Moire scales and Moire fringes, diffraction measurement technique.

Computer Aided Measurement Techniques: data acquisition, automatic inspection machines, knowledge based system. Vision based inspection system: Basics of image acquisition, Basics of machine vision, morphological operation for shape analysis. ENG(CMERI) 3-386

ADVANCED FLUID FILM BEARINGS

L-T-P-C : 3-1-1-4

Course Coordinators: : Dr. N. C. Murmu Basic equations of lubrication, analytical solution –finite difference and finite element methods, and application to idealized hydrodynamic bearings. Hydrodynamic instability, mechanism of hydrodynamic instability, oil whirl and stability. Externally pressurized oil bearings – hydrostatic lubrication, fixed restrictors, circular step bearings, rectangular thrust bearings and numerical solution Gas lubricated bearings –governing equations, limiting solutions, slider bearings, externally pressurized gas bearings, porous bearings and whirl instability in journal bearings. Squeeze film bearing –parallel surface bearings, step bearings and some problems under squeeze film lubrication. Elastohydrodynamic lubrication, theoretical considerations, Grubin type solution, film thickness equations, different EHL regimes. ENG(CMERI) 3-387

WEAR OF MATERIALS & SURFACE MODIFICATIONS TECHNOLOGIES

L-T-P-C : 3-1-1-4

Course Coordinators: : Dr. N. C. Murmu Surfaces and Substrates: Surface topography, physico-chemical aspects of solid surfaces, surface interactions. elastic contacts, elastoplastic contacts and importance of substrate. Friction and Wear: Laws of friction, mechanisms of friction, friction space, stiction, stick slip, surface temperature. Abrasive wear, Adhesive wear, Erosion, Corrosive wear, Fatigue wear, Delamination of wear, and Fretting wear. Applications: Wear Behavior of Engineering Materials, Metallic materials, Ceramics, Polymers and Industrial applications. Surface Modifications Techniques: Electro deposition, Flame spraying, Plasma spray, Physical vapour deposition, Chemical vapour deposition, HIP surface treatments, Sol-gel coatings and Spin coating methods. Lab Works, Tutorials and Mini Project. ENG(CMERI) 3-388

FUNCTIONALIZATION OF SURFACE AND INTERFACES OF BIOMATERIALS

L-T-P-C : 3-1-1-4

Course Coordinators: : Dr. R. R. Sahoo Introduction to biomaterials: Metallic, Ceramic, Polymeric, Composite, hydrogel, natural materials. Characterization of materials, mechanical properties, thermal properties, surface properties and adhesion. Biofunctionalization of Surfaces, Self-assembly, Polymer directed self-assembly of inorganic biomaterials – Biomimetics; surface and intermolecular forces. Surface modification, 2D and 3D scaffolds for tissue engineering; Materials for artificial blood vessels, mechanical heart valves, breast implants, orthopedic joints, dental fillings, chin augmentation, devices such as intravenous catheters and drug delivery vehicles, intra-ocular lenses, burn dressings, sutures, Biomaterials for tissue replacement; biologically functional biomaterials; testing and clearance of biomaterials; evaluation of biomaterials. Hip Joint Prosthesis Fixation: Problems and Possible Solutions, orthopedic implants.

ENG(CMERI) 3-389

NANOTRIBOLOGY AND ITS APPLICATION TO MICROSYSTEMS

L-T-P-C : 3-1-1-4

Course Coordinators: : Dr. R. R. Sahoo Introduction to Micro and Nanotribology. Overview of surface roughness, adhesion, friction, wear and lubrication. Mechanisms of solid-solid adhesion, liquid medicated contact, lubrication approaches. Characterization techniques – SFA, STM, AFM, Nanoindenter. Nanotribology, nanomechanics and material characterization using AFM. Overview of surface imaging, adhesion, friction, wear, indentation and lubrication. Metals, Ceramics, Self-Lubricating Films. Tribological Properties of Metallic and Ceramic Coatings. SelfAssembly for Controlling Hydrophobicity, Friction and Wear. Nanotribology of microsystems, examples with tribological issues. Nanotribological studies of Microsystems’ materials and lubricants, superlubricity, Reversible adhesion etc. Nanomechanics of Nanostructure, measurement of mechanical properties of Nanostructure, FEM analysis of Nano-beams with roughness etc. ENG(CMERI) 3-390

ADVANCED PASSIVE AND ACTIVE MAGNETIC BEARINGS

L-T-P-C : 3-1-0-4

Course Coordinators: : Dr. Pranab Samanta Introduction to PMB, basic principles, configurations, merits and demerits, modeling and simulation of PMB. Electro-magnetics and mathematicl model of AMB, electromechanical structure and operating principles, stored magnetic energy and force, radial magnetic bearing, unbalance pull force. Basics of active control, introduction to magnetic bearing controls, active suspended machine, PID Control, adjustment of PID gains, interference in two perpendicular axes, unbalance force and elimination. Methodology for AMB suspended rotordynamics investigation,flexible rotor AMB characterization and control, two axes system, four-axis and five axis systems. Introduction to ferrofluid, principles, synthesis, characterization, ferrodydrodynamics, design of ferrofluid bearing. Mini Project / Lab Works,Tutorial. ENG(CMERI) 3-391

LATTICE BOLTZMANN AUTOMATA

L-T-P-C : 3-1-0-4

Course Coordinators: : Dr. Dipankar Chatterjee and Dr. Bittagopal Mondal Introduction and Kinetics of Particles: Kinetic theory, Particle dynamics, Distribution function, Boltzmann distribution. The Boltzmann Equation: Introduction to Micro, Macro and Mesoscopic Modeling, Lattice Gas Cellular Automata (LGCA), From LGCA to LBM (Lattice Boltzmann Model), Boltzmann Transport Equation (BTE), Derivation of LBM from BTE, Chapmann-Enskog Expansion, The BGK Approximation, One, Two and Three dimensional Lattice Arrangements, Equilibrium Distribution Function. The Diffusion Equation: Finite Difference Approximation, Lattice Boltzmann Method, Boundary Conditions, Two Dimensional Heat Diffusion. The Advection-Diffusion Problem, Implementation of LBM for basic fluid flow and heat transfer problems, Some advanced topics like turbulence, two phase flow, MHD etc. ENG(CMERI) 3-392

ROBOTS WITH JOINT FLEXIBILITY: MECHANICS AND CONTROL

L-T-P-C : 3-1-0-4

Course Coordinators: : Dr. Soumen Sen and S. Nandy From Rigid to Flexible Robots, Joint flexibility, Stiffness/Impedance variability, Flexible Tendon Driven System, Tendon Routing, Manipulator Statics and Stiffness, Explicit and Antagonistic stiffness variability, Tendon manipulability, Stiffness Controllability, Dynamic model of flexible joint for serial robot, Singular perturbation

technique, Control methods for flexible joint robots, Feedback linearization technique, Cartesian Impedance control, Simultaneous control of motion and stiffness in variable stiffness mechanisms. New generation of human friendly robots, Macro/Mini actuation approach, Antagonistic actuation approach, Variable stiffness in legged machines, exoskeletons and artificial prosthesis. ENG(CMERI) 3-393

ARTIFICIAL INTELLIGENCE AND DATA MINING

L-T-P-C : 3-1-0-4

Course Coordinators: : Dr. Ranjit Ray and D. Banerjee Foundation of AI and history of AI intelligent agents, Searching for solutions, uniformed search strategies, Local search for constrain satisfaction problems, Rule based deduction systems, Decision Support System, Data Prediction , Sequence Discovery , Fuzzy Sets and Fuzzy Logic, Game Playing Data Mining, Knowledge Representation & Reasons logical Agents, Resolution, Decision Theory, Classical planning problem, Language of planning problems, planning with state – space search, Robot Motion Planning, Overview of machine learning, Decision tree learning, Two layer artificial neural networks, Multi-layer artificial neural networks, Inductive logic programming, Genetic algorithms, Genetic programming. ENG(CMERI) 3-394

ADVANCED COMPUTER VISION

L-T-P-C : 3-1-0-4

Course Coordinators: : Dr. S. Majumdar Review of Computer Vision Fundamentals Model Fitting: Bilinear models, symmetric model, asymmetric model, classification, extrapolation, translation of the data set. Structure from Motion & Image Motion: Domain dependent & domain independent motion understanding, optical flow-adjacency, depth and collision, surface orientation and edge detection, egomotion, understanding of image sequences and probability theory for clustering. Review of Bayes Theorem: Statistical decision theory, Bayes Theorem, Classifier Types-parametric, nonparametric. Classifier training-supervised, unsupervised. Maximum likelihood estimation, Bayesian estimation. Object Recognition Pose Estimation using analytical or geometrical methods and learning based methods. Object Tracking with adaptive background generation & shadow removal using single & multi camera tracking techniques with common algorithms for filtering and data Association Other topics include face recognition. ENG(CMERI) 3-395

ADVANCED NAVIGATION & DATA FUSION

L-T-P-C : 3-1-0-4

Course Coordinators: : Dr. S. Majumdar Review of Navigation Sensors & Navigation methods Probabilistic modeling & its applications to Navigation & Data Fusion (Bayes Filter) Feature detection & Representation & Map building Data Association methods: Innovation Gate, Probabilistic Data Association, Joint Probabilistic Data Association, Multiple Tracking, Correlation based method Simultaneous Localization and Map Building: Theory & Application to Navigation, Multisensor data fusion application, sonar, vision, laser radar, INS, GPS etc. AI based Robotics, Qualitative Modeling Methods, Qualitative and Behavior based Navigation, Learning Systems, Perception Modeling and its application to Robotics.

ENG(CMERI) 3-396

MOBILE ROBOTICS

L-T-P-C : 3-1-1-4

Course Coordinators: : D. Banerjee and S. Nandy Basic Components & Modelling: Introduction, Design considerations, Key issues, Locomotion, Configurations (Legged, Wheeled & Hybrid), Kinematics, Constraints, Dynamics. Sensing & Perception: Sensors, Levels of integration & advantages, Smart Sensors, Interoceptive & Exteroceptive sensors, Sensors for mobile robots (Dead reckoning, Heading, GPS, Vision, Motion sensors, Range finders etc.), Modeling (Allan Variance), Feature extraction. Navigation, Motion Planning & Control: The challenges of Navigation & Localization, Odometry and other dead reckoning methods, Active beacon navigation system, Land mark navigation, Occupancy grids, Path planning, Kalman Filter, SLAM Classical control methods (PID, FLC etc.), Obstacle Avoidance methods. Advanced Robotics paradigms: Behavioural & Probabilistic Robotics. ENG(CMERI) 3-397

ADVANCED ROBOT DYNAMICS AND CONTROL

L-T-P-C : 3-1-0-4

Course Coordinators: : Dr. Soumen Sen and S. Nandy Introduction to dynamics; Spatial velocity, acceleration and force; Transformations; Momentum and Inertia; Equations of motion of multibody system and constrained motion; Robot kinematics, serial and parallel manipulators, joint models; Forward and inverse dynamics of serial and parallel manipulators, Newton-Euler algorithm, Euler-Lagrange algorithm, Robot-environment contact and impact; Multifingered hand and cooperative multi-manipulator kinematics and dynamics, internal forces and internal motion; Lyapunov stability theory; Position control and trajectory tracking; Joint and task space control; Control of constrained manipulators; Force and Impedance control; Dynamics of manipulator on mobile platform; Modelling and dynamics of underwater robots/vehicles; Thrusters; Vehicle-manipulator dynamics; Control and stability of AUV.

MTech & PhD Thesis Work ENG(CMERI) 2-098

MTech DISSERTATION PART-I

L-T-P-C : 0-8-16-16

ENG(CMERI) 2-099

MTech DISSERTATION PART-II WITH VIVA VOCE

L-T-P-C : 0-8-16-16

ENG(CMERI) 3-099

PhD DISSERTATION WITH VIVA VOCE

L-T-P-C : --------

CSIR-CMMACS ENG (CMMACS)- 1-001: Research Methodology : 1-1-0-2 Course Coordinator: P Goswami Introduction, Research terminology and scientific methods, different types and styles of research, role of serendipity, creativity and innovation, Scientific and critical reasoning skills, art of reading and understanding scientific papers, literature survey. Measurements in research - primary and secondary data. Quantitative methods and data analysis, Qualitative analysis, Communicating research results. Designing and implementing a research project. Ethics in research, Plagiarism, Case studies. Laboratory safety issues – lab, workshop, electrical, health & fire safety, safe disposal of hazardous materials. Role & importance of communication, Effective oral and written communication. Technical report writing, Technical/R&D proposals, Research paper writing, Dissertation/Thesis writing, Letter writing and official correspondence. Oral communication in meetings, seminars, group discussions; Use of modern aids; Making technical presentations. ENG(CMMACS)-2-416: Transport Phenomena: 2-1-0-3 Course Coordinator: Partha Sarathi Goswami Introduction to engineering principles, units and dimensional analysis, overview of basic mathematics (vectors, tensors etc). Molecular and convective transports, Shell balances: Mass, Momentum and energy balances, Navier Stokes equations, Potential and viscous flows. Approximations in fluid mechanics: pseudo steady state and lubrication, inter-phase transport coefficients, unsteady state microscopic balances for mass, momentum and energy transport. Recommended Books · · · ·

Bird, R.B, Stewart, W.E. and Lightfoot, E.N., Transport Phenomena, Wiley, 1994. Denn, M.M, Process Fluid Mechanics, Prentice Hall, 1980. Whitaker, S., Fundamental Principles of Heat Transfer, NewYork, Pergammon, 1997. Cussler, E, L., Diffusion. Mass Transfer in Fluid Systems, Cambridge, 1985.

ENG(CMMACS)-2-417: Finite Element Method: 3-0-0-3 Course Coordinator: P Seshu Approximate solution of linear differential equations -- Weighted residual techniques. Collocation, Least Squares and Galerkin methods. Use of piecewise continuous approximation functions. Basis of Finite Element Method. Formulation of element level equations and assembly into system level equations. One dimensional example problems. Elements of Variational calculus. Minimisation of a functional. Principle of minimum total potential. Piecewise Rayleigh - Ritz method and FEM. Comparison with weighted residual method. Two dimensional finite element formulation. Isoparametry and numerical integration. Finite element formulation for transient dynamic problems. Algorithms for solution of equations. Recommended Books 1. Bathe, K. J., Finite element procedures in Engineering Analysis, Prentice Hall of India, 1990. 2. Cook R.D., Malkus. D. S., Plesha M. E. and Witt R. J, Concepts and Application of Finite Element Analysis, 4th Ed., John Wiley, 2005. 3. Huebner K. H., Dewhirst D. D., Smith D. E. and Byrom T. G., The Finite Element Method for Engineers, John Wiley, New York, 2004. 4. Reddy J. N., An Introduction to the Finite Element Method, 3rd Ed., Tata McGraw Hill, New Delhi, 2005. 5. Seshu P., Finite Element Analysis, Prentice Hall of India, 2003. 6. Zienkiewicz, O. C., and K. Morgan, Finite elements and approximation, John Wiley, 1983. 7. Zienkiewicz O. C, Taylor R. L. and Zhu J Z., The Finite Element Method: Its Basis and Fundamentals, 6th Ed., Elsevier, 2005 ENG(CMMACS)-2-418: Statistical and Computational Methods: 2-1-0-3 Course Coordinator: N K Indira Basic Concepts: Discrete and continuous data, Sample and Population, Events and Probability, Frequency, Table and Frequency distribution, Random variable and expectations, Measures of central tendency, dispersion and coefficient of variation, Moments and moment generating functions. Regression and Correlation: Linear regression analysis, Nonlinear regression analysis, Multiple regression Correlations. Probability and probability distributions: Discrete probability distributions and Continuous Probability distributions.

Classical Time series analysis: Measurement of trend, Measurement of seasonal fluctuations, Measurement of cyclic fluctuations. Stochastic time series analysis: System definition, System analysis, Model formulation, Modelling procedure, Estimation and validation. Correlation systems: Principal component analysis, Factor analysis. Analysis of variance. One way classification and Two way classification. Statistical analysis and hypothesis testing. Sampling and sampling distributions, Parametric estimation, Tests of hypothesis, Nonparametric method. Recommended Books: 1. Goon,A.M.; Gupta, M.K. And Dasgupta, B. An Outline of statistical theory. 2. Goon,A.M.; Gupta, M.K. And Dasgupta, B. Fundamentals of Statistics. 3. Hogg,R.V. And Craig,A.T. Introduction of mathematical statistics. 4. Box, G.E.P and Jenkins, G.M Time series analysis forecasting and control 5. Fulury, B.Common Principal component and related multivariate models 6. Nelson, C.R. Applied time series for forecasting 7. Irving W.B. Applied Statistical methods 8. Patel J.K.; kapadia,C.H. And Owen D.B Handbook of statistical distributions 9. Mood, A.M; Graybill, G.C Introduction to the theory of statistics ENG(CMMACS)-2-419: Global Navigation Satellite System (GNSS) theory and it applications: 2-1-0-3 Course Coordinator Sridevi Jade Introduction to GNSS geodesy, GNSS theory, GNSS reference frames, sources of errors and correction, positioning using GNSS observables, GNSS data collection, data processing and analysis, GNSS applications for Geoscience, Modelling of GNSS derived surface deformation. Introduction to GNSS geodesy covers the state of art on Global Navigation Satellite systems, its components, geodesy, Military and Civil applications. GNSS reference frames: Introduction to celestial and terrestrial reference frames, Earth Centered Earth fixed reference frame and earths pole of rotation. Sources of errors and corrections: Introduction of positioning using GNSS satellites, errors involved covering orbit, clock errors, troposphere and ionosphere errors, miscellaneous errors. Positioning using GNSS observables: To determine the precise position and time, error correction, different types of positioning. GNSS data and processing theory: Models involved in data processing and analysis. GNSS applications to Geoscience: Surveying, continental deformation studies, landslide hazard mapping, Glacier dynamics, Volcano deformation, troposphere and ionosphere modeling, InSAR (Interferometric Synthetic Aperture Radar), GIS (Geographical Information System) etc. Modelling of GNSS deformation: brief introduction of different kind of modeling techniques that are currently being used.

Recommended Books: 1. GPS Theory and Practice – B. Hofmann-Wellenhof, H. Lichtenegger and J.Collins 2. Introduction to GPS – Ahmed E1-Rabbany 3. Principles of GPS – P.S. Dhunta 4. Global Positioning System: Theory and Applications I & II Parkinson and Spilker 5. GPS Satellite Surveying – Leick ENG(CMMACS)-2-420: Principles and Techniques of Mathematical Modelling: 2-10-3 Course Coordinators: V Y Mudkavi This course will provide an overview of principles and techniques of mathematical modelling used by engineers and scientists with a bias to fluid mechanics. The following topics will be discussed: 1. Mathematical modelling. What is modelling? Properties of a model. Why do we model? Some examples. The four paradigms and relevance of modelling. 2. Order of magnitude analysis. Dimensional arguments. 3. Complex variable. Power series. Branch points. 4. Vectors and tensors. Linear vector spaces. Matrix theory. 5. Vector fields, their Divergence and Curl. Classification and representation of vector fields. 6. Numerical methods. Numerical differentiation and integration. Interpolation. Initial and boundary value problems. Euler and Runge-Kutta methods. Multi-step methods. 7. Dynamics: Geometric ideas. 8. Model equations in fluid mechanics. Recommended Books 1. Bender, E. A. An Introduction to Mathematical Modeling. John Wiley and Sons. 1978. 2. Goldreich, P., Mahajan, S., Phinney, S. Order-of-Magnitute Physics: Understanding the Wold with Dimensional Analysis, Educated Guesswork, and White Lies. 1999. 3. Nearing, J. Mathematical Tools for Physics. www.physics.miami.edu/nearing/mathmethods/. 2003. 4. Koonin, S. E. Computational Physics. Benjamin/Cummings. 1986. 5. Golub, G. H., Ortega, J. M. Scientific Computing and Differential Equations: An Introduction to Numerical Methods. Academic Press. 1992. 6. Aris, R. Mathematical Modelling Techniques. Dover. 1995. 7. Abraham, R. H., Shaw, C. D. Dynamics: The Geometry of Behavior. AddisonWesley. 1992. 8. Aris, R. Vectors, Tensors and the Basic Equations of Fluid Mechanics. Dover. 1962.

ENG(CMMACS)-2-421: High Performance Scientific Computing: 2-1-0-3 Course Coordinator : G K Patra Modern computer architectures, Programming and Tuning Software, Shared-Memory Parallel Processors, Scalable Parallel Processing, Scientific data formats, Open source application software Basic concepts in parallel computing, parallel algorithms, Introduction to message passing and MPI programming, embarrassingly parallel problems, Problem decomposition, graph partitioning, and load balancing, introduction to shared memory and OpenMP programming techniques, parallel direct and iterative methods, programming on different parallel architectures, applications relevant fields, Debuggers HPC best practices, Linux shell programming, sequential programming, compiler optimization, Multi-processor parallel programming, benchmarking and performance evaluation on different architecture, Visualization of different data formats. Recommended Books 1. High Performance Computing, Kevin Dowd, O'Reilly Series, 1993. 2. Introduction to High-Performance Scientific Computing ©2010 (Victor Eijkhout) 3. High Performance Computing For Dummies, Douglas Eadline, Wiley Publishing, Inc. 4. High Performance Computing: Paradigm and Infrastructure, L. Yang and M. Guo, ohn Wiley. 5. Designing and Building Parallel Programs, Ian Foster, Addison Wesley, 1995 6. MPI: The Complete Reference, Marc Snir, Steve Otto, Steven Huss-Lederman, David Walker, Jack Dongarra, The MIT press, 1996 7. How to write Parallel Programs, A first Course, By Nicholas Carriero and David Gelernter, The MIT press, 1992 ENG(CMMACS)-2-422: Nonlinear Dynamics: 2-1-0-3 Course Coordinator : T R Ramamohan Introduction/Phase Space, Plane and Portraits : Linear Systems and their classification;Existence and uniqueness of solutions; Fixed points and linearization; Stablility of equilibria; Pendulum Oscillator,Dufing oscillator,Lindstedt`s method; Conservative and reversible systems. Limit cycles: The Van der Pol oscillator, Method of averaging; Relaxation oscillators; Weakly Nonlinear Oscillators; Forced Duffing oscillator, method of multiple scales; Forced Van der Pol oscillator,entrainment, Mathieu`s equation, Floquet Theory, Harmonic Balance. Bifurcations: Saddle-node,transcritical,and pitchfork bifurcations; Center manifold theory; Hopf bifurcation; Global bifurcations; and Poincare maps. Chaotic Dynamics : Lorentz equations; Lorentz map ; Logistic map; Lyanpunov Exponents; Fractal sets and their dimensions; Box ,point wise and correlation dimensions; Strange attractors; Forced two-well oscillators

Time Series Analysis: State space approach Recommended Books 1. Julien C.Sprott , “Chaos and Time-series Analysis”, Oxford University Press 2003; 2. Mark Shelhamer, “Nonlinear Dynamics in Physiology: a State Space Approach”, World Scientific, 2007 3. Edward Ott, “Chaos in Dynamical Systems”, Cambridge University Press, 1993 4. K.T.Alligood, T.D.Sauer, and J.A.Yorke, “CHAOS-An introduction to Dynamical Systems”, Springer, 1996 5. Steven H. Strogatz, “Nonlinear Dynamics and Chaos” Indian edition published by Levant books, 2007 ENG(CMMACS)-2-423: Applied Computational Methods: 2-1-0-3 Course Coordinator : V Senthilkumar Ordinary Differential Equations: Initial Value Problems: Single step methods, Multi step methods Boundary Value Problems: Shooting Method, Finite Difference Methods, Finite Element Method Partial Differential Equations: Finite Difference Discretization, Finite difference treatment of 2nd order nonlinear PDE of parabolic, elliptic types, Hyperbolic problems Higher Order Methods: Spectral Method, Pesudospectral Method Recommended Books: · · ·

Numerical Methods for Scientific and Engineering Computation– M.K.Jain, S.R.K.Iyengar and R.K.Jain, New Age International Publishers Computational Methods for Partial Differential Equations– M.K.Jain, S.R.K.Iyengar and R.K.Jain, New Age International Publishers Numerical Methods for Engineers and Scientists- Joe D. Hoffman, McGraw-Hill, Inc

ENG(CMMACS): 2-424: Numerical Analysis and Fortran Programming: 3-0-0-3 Course Coordinator : P S Swathi This is a programming-intensive course which will make the students write Fortran codes for numerical analysis topics. There is no separate lab component. Programming assignments will be integral to the course and not considered as lab assignments. The topics covered will include: Basics of computer floating point arithmetic, Fortran programming and debugging, Taylor series, solution of algebraic equation, linear systems – direct and iterative methods, eigen value problems, least squares and singular value decomposition, interpolation and extrapolation, numerical differentiation and integration, numerical solution of ordinary differential equations

ENG(CMMACS)- 3-001: Advanced Self Study:0-2-4-4 Aims to train the student on learning, on one's own, topics that are not formally taught in a course. This would involve primarily three components - collection of relevant literature on a chosen topic, organization of relevant material into a written report based on candidate's own critical understanding and finally presentation of the findings in front of wide audience in the form of a seminar. Thus communication skills are also expected to be honed up (4 credits) Course Coordinator: PhD Guide ENG(CMMACS)-4-001: CSIR-800 Societal Programme: 0-0-8-4 The students have to undertake a project in rural area for 6-8 weeks in line with CSIR800 programme which is primarily prepared at empowering 800 million Indians by way of S & T inventions. The theme for the project may be chosen from CSIR-800 document and as per expertise available at individual laboratory. Students will choose the topics in consultation with Doctoral Advisory Committee (DAC). Course Coordinator: Dr P Goswami / Dr Ehrlich Desa ENG(CMMACS)-4-002: Project proposal writing: 0-1-6-4 Two subject proposals to be prepared before comprehensive examination by selecting topics of high relevance and novelty, and will have state-of-the art review, methodologies, recommendations etc. (2 credits each) Course Coordinator: PhD Guide

CSIR-CSIO PHY/ENG(CSIO)-1-001:1-1-0-2: Research Methodology

Course Coordinator: Dr HK Sardana Introduction to Research: Importance, study of literature, defining research problem, hypothesis formulation, experimental design Data Collection and Measurement: Methods and techniques, probability and probability distributions, sampling and sampling designs Data Analysis: Testing of hypothesis, statistical tests and analysis, data interpretation, multivariate analysis, model building, forecasting methods Report writing and Presentation: Ethics in research, Plagiarism, substance of reports, formats, referencing, oral presentation skills General practices followed in Research – literature and data management, Safety practices in the laboratory, Intellectual property rights (IPR). PHY/ENG(CSIO)-1-311:3-1-0-3: Mathematics for Engineers and Scientists

Course Coordinator: Dr GS Singh Calculus: Differential Calculus, Partial differentiation, Integral Calculus, Multiple integrals, Vector Calculus Complex Analysis: Complex numbers and functions, Matrices, Calculus of Complex Functions. Differential Equations: Differential equations of first order, linear differential equations, Differential equations of different type, series solution of differential equations and special functions, partial differential equations. Series & Transforms: Series, transforms, and complex transforms. PHY/ENG(CSIO)-3-001:0-2-4-4: Advanced Self Study Course Coordinator: PhD Guide The main focus of this course is to encourage self-learning in the niche areas of the candidate’s interest. The candidate is expected to do an extensive literature survey in the chosen research area and submit an written report of the work and present the work to group of experts in the form of a seminar. PHY/ENG(CSIO)-4-001:0-1-6-4: Project proposal writing Course Coordinator: Dr Pawan Kapur Two subject proposals to be prepared before comprehensive examination by selecting topics of high relevance and novelty, and will have state-of-the art review, methodologies, recommendations etc. (2 credits each) PHY/ENG(CSIO)-4-002:0-0-8-4: CSIR-800 Societal Programme

Course Coordinator: Dr Pawan Kapur The students have to undertake a project in rural area for 6-8 weeks in line with CSIR-800 programme which is primarily prepared at empowering 800 million

Indians by way of S & T inventions. The theme for the project may be chosen from CSIR-800 document and as per expertise available at individual laboratory. Students will choose the topics in consultation with Doctoral Advisory Committee (DAC). ENG(CSIO)-1-486:3-1-0-3: Circuit Theory and Electronic Devices Course Coordinator: Dr Pawan Kapur Electric circuits and components: Introduction, basic electrical elements – resistor, capacitor, inductor, Kirchhoff’s laws, voltage and current sources and meters, network theorems, AC/DC circuit analysis, transformer, impedance matching, grounding and electrical interference. Semiconductor electronics: Junction diode, Zener diode, analysis of diode circuit, three terminal devices - BJT, JFET, MOSFET, four terminal devices, SCR, DIAC,TRIAC, photo devices - photo diodes, photo transistors, LED, LCD, opto-isolator and opto-couplers, amplifiers: BJT, FET amplifier, single stage, multistage power amplifiers – class A, B, C and D amplifiers, operational amplifiers: specifications, characteristics and applications. Introduction to computing: Number system and code conversion, logic gates, Boolean algebra, combinational logic circuits, sequential logic circuits – latch, RS, JK, T, D flip flops, shift registers, counters, digital building blocks: decoder, encoder, MUX, DMUX, A/D, D/A converters, memories, programmable logic devices, microprocessors, microcontrollers, Display devices. Power devices: Construction, rating, characteristics and applications of SCR, TRIAC, IGBT. ENG(CSIO)-1-487:3-1-0-3:Mechanisms, Materials and Manufacturing Course Coordinator: AD Kaul Mechanical systems: Types of motion, kinematic chains, freedom and constraints, slider-crank mechanisms, machine elements. Materials and Processing: Engineering materials, machining processes: conventional, special purpose machines Measurements & Instruments: Mechanical engineering measurements & instruments: linear, angular, and surface measurements, force, temperature. ENG(CSIO)-2-486:3-1-0-3: Signal Processing Course Coordinator: Dr Amod Kumar Signals and Systems, Continuous time signals, sampling theorem, discrete time signals and systems, classification Transforms, Analysis and Filters, Analysis of linear systems, correlation of discrete time signals, frequency domain analysis, DFT, FFT, z-transform, IIR/FIR digital filter design, basics of DSP processors Signal processing in instrumentation, case studies. ENG(CSIO)-2-487:3-1-0-3: Computer Aided Design and Simulation Course Coordinator: AD Kaul Introduction to Optical Design: Paraxial Optics, Geometrical Optics, Wave Optics, Finite ray tracing, Merit Function and its General Features, Numerical Minimization Methods of Merit Function, Minimization Subject to Constraints. Design of Popular Optical Systems: Telescopes: Refractive & Reflecting, CCD Camera Optics, HUD Optics

Computer Aided Design for PCB layout: Analog, Digital & Mixed signals, Ground and Power Supply requirements; Active and Passive components behaviour; mixed signal simulation. System Ruggedisation Fundamentals: Environmental Parameters, Thermal analysis and EMI Fundamentals. Introduction to CAD/CAE/Simulation: Hardware and Software in CAD/CAE applications; graphics input and output devices; Introduction to 2D, 3D drawings and projections. Modelling approaches: Geometric modelling, Wire frame modelling, Part modelling, Assembly modelling, Sheet metal modelling, Rendering and Visualisation. Introduction to Finite Element Analysis: Static, Frequency & Thermal Analysis ENG(CSIO)-2-488: 3-0-0-3: Human Physiology Course Coordinator: Dr Viren Sardana Cell and Tissue: Introduction to cell, multicellular organization, basic structure and organization of cell, cell organelles, tissue structure, types of tissue. Cardiovascular system: Anatomy of cardiovascular system, cardiac muscle, electrical conduction in heart, brief introduction to ECG/EKG, types of circulation, working of heart and cardiac cycle. Respiratory system: Anatomy of respiratory system, gas exchange, physiology of respiration, spirometry, respiratory volumes and capacities. Digestive system: Anatomy of digestive system, process of digestion, absorption and excretion, role of digestive enzymes and juices, hepatobiliary system. Nervous and endocrine system: Anatomy of nervous system and endocrine system, action potential, division of nervous system, nerve tissue, transmission across synapse, reflexes, neural control of different major body stems, sleep cycle, special senses (eye, ear, smell), role of hypothalamus, pituitary, different hormones and their role. Musculoskeletal system: Types of muscles, muscle contraction physiology, types of bones, bone macro and micro anatomy, bones in body, cartilage types, joints types, movement at joints, fracture types and healing. Urinary system: Anatomy of renal system, working of the kidneys, process of urine concentration and bladder control, maintenance of acid-base balance. Immune system: Immunity, Types of immunity, components of Immune system, antibodies, antigen, blood groups, detection of antigen/antibody as basis of disease diagnostics. ENG(CSIO)-3-486:3-0-2-4: Digital Image Processing Course Coordinator: Dr HK Sardana Introduction: Elements of visual perceptions, digital Image sensing, sampling and quantization, digital image representation, basic relationship between pixels, elements of digital image processing system. Image transforms: Discrete Fourier transform and properties, separable image transforms, image enhancement. Wavelet transforms. Restoration and Reconstruction: Image restoration, image segmentation, image reconstruction from projections. Statistical pattern recognition: Cluster analysis, feature selection & extraction, syntactic pattern recognition: stochastic languages, problem solving methods for pattern recognition. Case studies: Medical image processing, colour image processing, thermal image processing.

ENG(CSIO)-3-487:3-0-2-4: Statistical Analysis & Machine Intelligence Course Coordinator: Dr HK Sardana Statistical Analysis: Statistics In Research, Common Terms in Statistics, Constraints in Research, Population and Sample, Choosing Appropriate Sample Size, Sampling, Errors in Sampling, Data Collection, Bias in Statistics, Data representation, Types of Data, Data Analysis, Measures of Central Tendency, Standard deviation, Variance, Standard Error of Means, Gaussian Distribution, Normal Distribution Curve, Skewness, Tests of Significance –t/z/ANOVA, chi square test, correlation and regression analysis. Applied Machine Learning: Linear algebra revisited, ML Tools, Introduction to Machine Learning –Supervised Vs. Unsupervised Learning, Linear regression, Logistic regression, Regularization, Neural networks- Representation and Learning, Machine Learning System Design, Support Vector Machines, Clustering, Dimensionality reduction, Anomaly detection, Recommender systems, Large scale machine learning, Applications- enose, iTongue, cancer, Iris, Boston housing, sonar, wine etc . Hybrid systems: Uncertainty and imprecision, fuzzy systems, linguistic rules, approximate reasons, neuro-fuzzy systems, genetic algorithms and evolving neural networks, applications in control, inspection, monitoring, forecasting, recognition and diagnosis, Applications/Case Studies: Engineering design optimisation, optimiser behaviour evaluation through stochastic analysis, performance analysis, optical design and engineering, mechatronic products, agro applications. ENG(CSIO)-3-488:3-0-2-4:Biological Control Systems Course Coordinator: Dr Pawan Kapur Introduction: Control systems, transfer functions, mathematical approaches, system stability, feedback concept and stability analysis, Biological control system, comparison with engineering control, transfer of various bio-chemicals between compartments, biological receptors and actuators, characteristics, transfer function model, bio-feedback mechanism. Regulation: Regulation of acid-base balance, regulation of extra cellular water and electrolytes, process controls-cardiac rate, blood pressure, respiratory rate and blood glucose regulation. Endocrine control, Pharmaco modelling-drug distribution system, regulation of interstitial fluid volume. CO2 regulations. Modelling of Human Systems: Modelling of human cardiovascular system, respiratory system, thermal regulatory system, etc, parameters involved, control system models etc, heat loss from the body, model of heat transfer between subsystems of human body like skin, core, body in relation to environment. Bio-mechanics: Muscle behaviour to excitation & EMG analysis, stiff leg gait model, Gait pattern in terms of step size, Step frequency, Comfortable walking & gait behaviour during exercise. Heat-lung information pathways under normal and exercise conditions in terms of O2 and CO2 balance. Hearing and Vision System: Information pathways for various sensory organs such as hearing, vision, smell, etc. Skull position & velocity sensing, auditory cupila dynamics, time & frequency response characteristics, papillary dynamics for optimum flux density as retina, cilliary muscles control, transient response, eye tracking problem and various information pathways, etc.

ENG(CSIO)-3-489:3-0-2-4: Bio Instrumentation Course Coordinator: Dr Amod Kumar Introduction - Cellular organization: Cell, Action potential of cell, Transport of substances across biological membrane. Cardiovascular system: heart, arterial and venous system, blood, cardiac cycle. Basics of ECG, PCG. Measurement of blood pressure by direct and indirect methods. Plethysmography. Defibrillators: DC defibrillators, AC defibrillators of capacitance discharge and delay line capacitance discharge with basic circuit diagrams. Types of electrodes and their features. Cardiac pacemakers: Asynchronous and Synchronous (demand) Mode of operation. External and Implantable Asynchronous pace makers. Working Principles, modes of triggering. Respiratory system: Trachea and Lungs. Respiratory Physiology. Spirometry, Ventilators. Nervous system and special senses: Nerve physiology. Basics of EEG. Electrodes used for measurement of EEG. Skeletal system: Classification of Bones, Joints and Muscles- Structure and function. Basics of EMG. Bipotential Electrodes: Electrode electrolyte interface, half cell potential polarization , electrode skin interface and motion artefact. Types of electrodes. Micro electrodes. Miscellaneous: Hearing aids, Heamodialysers- types of exchangers. Lasers in Surgery, Principles and applications of Endoscopes. Electrical hazards in hospitals: Patient electrical safety, types of hazards, patient isolation, physical effects of current, let – go – current, Micro shocks, different ways for electrical accident to occur, safety instruction circuits, electrical grounding & effects. ENG(CSIO)-3-490:3-0-2-4: Agri-Physics and Agro Control Systems Course Coordinator: Dr Pawan Kapur Measurement techniques and instruments for various agri-parameters such as pH, electrical conductivity, moisture content, temperature, relative humidity, viscosity/ consistency, rheology, heat transfer coefficient, visco-elastic behaviour, etc. Modelling of key agri-processes such as material carrier, extraction, clarification, concentration, crystallisation, drying etc. Typical case studies of level control, consistency control, bio-chemical reactions based on material balance, heat balance, population balance, etc. Instrumentation & control for various unit processes such as precision farming, cultivation under controlled atmosphere, photosynthesis, crop health monitoring, pesticide estimation, soil mapping, light flux density, etc. Case studies of some key agro-based industries in terms of instrumentation & control : automatic grading & sorting of fruits / vegetables, controlled environment storage system (seed potatoes), Juice clarification, evaporation and crystallisation process in cane sugar industry, instrumentation in tea processing such as withering, rolling/CTC, fermentation, drying, etc. Mushroom cultivation in environmentally controlled cropping houses, control system realisation, algorithm development (PID, PD2T2), tuning of controller, performance evaluation, identification techniques. ENG(CSIO)-3-491:3-0-2-4: Agro Mechanical Systems Course Coordinator: VPS Kalsi Agriculture Parametric Study: Field measurements, Soil dynamics & water resources, Agriculture field engineering, Pre & Post harvesting

Agriculture Engineering: Elements of machine design, Computer aided design, simulation & analysis, instrumentation & process control Farm Machinery: Tractor system & control, Production technology for agriculture machinery, Tractor mounted gadgets for pre & post harvesting, Resources of Irrigation, Conveyor systems, Grading & Sorting of fruits & vegetables, Storage chambers, Chilling, Humidification & Aeration units, Processing system (solar drying, juice extraction , clarification , filtration), Control valves & actuators, Material characterization Agriculture Economics: Agro environmental science, Principle of ergonomics & safety, Human engineering & safety, Precision farming & natural resource farming ENG(CSIO)-3-492:3-0-2-4: Optical Instrumentation Course Coordinator: Dr GS Singh Geometrical Optics: Optical Components: Lenses, Mirrors, Prisms; Diffraction Gratings, Optical System Layout, Basics of Lens Design, Zoom Lenses, Mirror and Catadioptric Systems, Optical Specifications and Tolerances Physical Optics: Apertures and Diffraction, Wave Aberrations and MTF, Fourier Optics & Optical Signal Processing; Diffractive Optics, Quantum Optics Optical Materials & Coatings: Optical Glass, Plastics, IR Materials, Anti Reflection Coatings, Reflection Coatings, Interference Filters Radiometry and Photometry: The Inverse Square Law; Intensity; Radiance and Lambert’s Law; the Radiometry of Images, Blackbody Radiation, Photometry, Illumination Devices ENG(CSIO)-3-493:3-0-2-4: Opto-Mechanical Systems Course Coordinator: Dr SV Ramagopal Module – i: Optical fabrication & metrology Optical materials, optical shop supplies, tools & fixtures, optical processors, optical processing, optical shop testing. Module – ii : Opto-mechanics: design, fabrication & metrology Opto-mechanical design process, environmental influences, mounting individual lenses, mounting multiple lenses. Module –iii : Display technology Principles, Emergent Technologies, Application Areas for Display Devices Including CRT, LCDs, Reflective Displays, Emissive Devices (OLEDs), Plasma Displays, Scanned Laser Displays, Digital Micro-mirror Devices. Fundamentals of Light & Vision, Display Electronics & Calibration; Display Measurement: Concepts, Techniques, And Instrumentation; Commercial, Industrial & Military Standards For Testing of SW & HW; Environmental & Performance Testing Parameters & Standards For Display Systems

CSIR-IICT PES 611: Numerical methods and Process Modeling : 3 Credits Fundamentals of mathematical modeling Chemical Process Modeling Numerical methods Process optimization Process simulation using Software Packages PES 612: Advanced Separation Processes : 3 Credits Fundamentals of Separation Processes Binary Separation Processes Multi-component Separation Processes Rate Based Separations Hybrid Separations Reactive Separations PES 613 : Reaction Technology : 3 Credits Homogeneous reactor design and analysis: Non-ideal reactors Heterogeneous reactors for fluid-fluid systems: Kinetic evaluation and design Heterogeneous reactors for fluid-solid systems: Kinetic evaluation and design Novel Reactor Configurations PES 711 : Process Engineering : 4 Credits Process Route Selection Process Flow sheeting Process optimization Process Equipment Design Advanced Process Engineering Concepts PES 614 : Advanced Chemical Engineering Thermodynamics : 3 Credits Basic concepts of thermodynamics Solution thermodynamics: Properties of mixtures Phase equilibria: VLE, LLE, VLLE, SLE Chemical reaction equilibria: Multi-reaction equilibria Introduction to molecular and statistical thermodynamics

PES 621 : Advanced Process Design : 3 Credits Heat transfer equipment design Mass transfer Equipment design Reactor design Process Instrumentation Process Safety and Hazard analysis Computer Aided Process Design PES 622 : Advanced Process Optimization : 3 Credits Unconstrained Optimization – single variable and multivariable Linear programming Nonlinear programming with constraints Mixed Integer Programming Global optimization Optimization of heat transfer applications Optimization of separation processes Optimization for Chemical Reactor Design and Operation PES 721 : Process Integration and Intensification : 4 Credits Introduction to process integration and intensification Heat Exchange Network Synthesis Mass Exchange Network Synthesis Reactor Network Synthesis Equipment based Process Intensification Method based Process Intensification PES 623 : Membrane Technology : 3 Credits Introduction to membrane separation processes Membrane transport theories Membrane preparation techniques Design and analysis and industrial applications of membrane processes Membrane reactors and membrane contactors PES 624 : Advanced Process Monitoring and Control :

3 Credits

Introduction to Advanced control systems Controllability, Observability and Stability Analysis State estimation and inferential control Adaptive Control Nonlinear Model based Control Model predictive control with linear, nonlinear and data-driven models Plant wide control Fault detection and diagnosis

PES 631: Research Methodology & Technical Communication Skills : 3 Credits Literature review Effective scientific writing & presentation Intellectual property management Research planning Effective written and oral communication Ethical issues PES 632: Artificial Intelligence in Process Engineering : 3 Credits Introduction to Artificial Intelligence (AI) Data reduction and classification methods Expert systems Evolutionary optimization methods Neural Networks - Concepts and Applications PES 633: Biochemical Engineering : 3 Credits Introduction to Biochemical Engineering Fermentation processes – microbial & enzymatic Bioprocess Modeling Bioreactor design Downstream processing operations

CSIR-IIP Course No: ENG(IIP): 3-610 L-T-P-C: 3-0-0-3 Course Title: Advanced Thermodynamics for Mechanical Engineers – 3 Credits Coordinating Faculty: Dr. Jasvinder Singh List of Faculty: Dr. Jasvinder Singh, Dr. S K Singhal, Sh. A K Jain, Dr. M. O. Garg Course Description Basic concepts P-V-T behavior of pure liquids; Application of thermodynamic Laws to real processes. Applications of equations of state; thermodynamic property calculations for fluid mixtures, Gibb’s & Helmholtz functions. Available & non-available energy, Irreversability Thermodynamics of flow systems Fundamental flow equation, Flow meters, thermodynamic analysis of flows in pipes, nozzles, and compressors, fluid temperature change and its measurement at high velocities. Heat Engines & Chemical Kinetics Thermodynamic Relationships, Clausius-Clapeyron Equation; Liquefaction of Gases, The JouleThomson Effect, Inversion Point on p-v-T Surface for Water; Rankine Cycle, Efficiency of an Internally Reversible Heat Engine; Chemical Kinetics: Reaction Rates, Rate Constant for Reaction, k, Chemical Kinetics of NO, The Effect of Pollutants formed through Chemical Kinetics Thermodynamics of Combustion Combustion of Hydrocarbon Fuels, Energy Equations, Chemistry of Combustion, Bond Energies and Heats of Formation, Enthalpy of Reaction, Chemical Equilibrium and Dissociation, Gibbs Energy, Stoichiometry, Van't Hoff Relationship, Dissociation Calculations, Effect of Dissociation & Fuel on Composition of Products, Combustion and Flames: Explosion Limits, Flames, Flammability Limits, Ignition, Diffusion Flames, Engine Combustion Systems Irreversible Thermodynamics & Fuel Cells Introduction, Definition of Irreversible or Steady State Thermodynamics, Entropy Flow and Entropy Production, Thermodynamic Forces and Thermodynamic Velocities, Onsager's Reciprocal Relation, The Calculation of Entropy Production or Entropy Flow, Thermoelectricity, Electric Cells, Fuel Cells, Efficiency of a Fuel Cell, Thermodynamics of Cells Working in Steady State, Diffusion and Heat Transfer ·

Distribution of Lectures

Name Dr. Jasvinder Singh Dr S K Singhal/ Sh A K Jain Dr. M. O. Garg

Designation Sr. Technical officer (3) Chief Scientist Director

No. of Lectures 20 16 4

Course No: ENG(IIP): 2-611 L-T-P-C: 3-0-0-3 Course Title: Internal Combustion Engines – 3 Credits Coordinating Faculty: Dr. S. K. Singal List of Faculty: Dr. S. K. Singal, Sh. A. K. Jain, Sh. Sunil Kumar Pathak, Sh. Devendra Singh, Dr. B. P. Pundir (External). Course Description Classification of Engines; Four and Two Stroke Engines, Auto and Diesel Cycles. SI Engines: Basic layout, Combustion characteristics, Ignition limits, P-Ɵ diagram. CI Engines: Ignition delay, Combustion characteristics, Pre-mixed and diffusion combustion, P- Ɵ diagram. Injection Systems: In-line injection system, Rotary and unit injector. Induction and Exhaust Systems: Induction and Exhaust Manifold configuration. Valves and Camshaft: Valve timing diagrams, operating conditions, valve overlap, cam design. Super charging and turbo charging: Super charging cycle, gas exhaust process. Simulation and modelling of IC engines. ·

Distribution of Lectures

Name Dr. S. K. Singal Sh. A. K. Jain Sh. Sunil Kumar Pathak Sh. Devendra Singh Dr. B. P. Pundir

Designation Chief Scientist Chief Scientist Sr. Scientist Scientist Ex. Prof. IIT (External)

No. of Lectures 10 10 5 5 Kanpur 10

Course No: ENG(IIP): 2- 593 L-T-P-C: 2-0-4-4 Course Title: Analytical Methods used in Petroleum Industry – 4 Credits Coordinating Faculty: Dr. Y. K. Sharma List of Faculty: Dr. S. S. Ray, Sh. A. Majhi, Sh. Pankaj Kumar Kanojia, Dr. R. C. Chauhan, Sh. Sarabhjeet Singh. Course Description Standard procedures: Principles, procedures and significance of ASTM/IP/UOP/IS test methods for evaluation and analysis of crude oil and its products; Atmospheric distillation (ASTM D 86); Vacuum distillation; Simulated distillation; True Boiling Point (TBP) distillation; Separation Methods: Chromatography; Gas Chromatography; Liquid Chromatography and Super Fluid Critical Chromatography (SFC); Spectroscopic techniques: Applications of ultra violet spectroscopy (UV); flourier transform infrared (FTIR); Nuclear Magnetic resonance (NMR) spectroscopy and Mass spectroscopy to petroleum products analysis; Elemental analysis: C, H, O, N and S; Metal analysis: Microanalysis; Xray fluorescence; plasma spectroscopy and atomic absorption spectroscopy; All the methods will be complemented with practical work in Laboratories. ·

Distribution of Lectures

Name Dr. Y. K. Sharma Dr. S. S. Ray Sh. Pankaj Kumar Kanojia Dr. R. K. Chauhan Sh. Sarabhjeet Singh Dr. A. Majhi

Designation Senior Principal Scientist Senior Principal Scientist Scientist Sr. Technical officer (3) Sr. Technical officer (3) Scientist

No. of Lectures 10 10 9 5 3 3

Course No: ENG(IIP): 2- 612 L-T-P-C: 3-0-0-3 Course Title: Tribology and Tribo – Component Design – 3 Credits Coordinating Faculty: Sh. G. D. Thakre List of Faculty: Sh. G. D. Thakre, Sh. B. M. Shukla. Course Description Introduction to Tribology: Friction and Wear; Surface phenomena, nature of surface and contact, surface interaction and friction. Effect of lubricants and surface films. Theory of friction. Mechanism of wear, types of wear – adhesive, abrasive, fatigue, corrosive etc. with reference to machine elements and subcomponents like bearings, clutches, brakes etc. Minimization of wear. Wear tests and testing machines. Basic principles of lubrication, lubrication theories; Hydrostatic, boundary, hydrodynamic and elasto-hydrodynamic lubrication. Generalized Reynolds equation, flow and shear stress. Lubricants: types and properties. Effective machinery lubrication, Machine fault detection through lubricant analysis. Laboratory practical on Tribology. Tribo-component design: Tribologically relevant properties of materials, friction materials and their application in clutch and brake linings. Antifriction/plain bearing materials, wear resistant materials. Surface modification techniques. Materials for specific applications eg. Gears, Seals, hydraulic components etc. Design, application and selection of various types of bearings – sliding and rolling element bearings. Mechanism of hydrodynamic instability. Dynamic characteristics of hydrodynamic journal bearings. Concept of air and magnetic bearings. Design and performance evaluation of Engine components, clutches, brakes seals etc. Application of soft computing techniques. Mini project/seminar on design and simulation. ·

Distribution of Lectures

Name Sh. G. D. Thakre Sh. B. M. Shukla

Designation Scientist Chief Scientist

No. of Lectures 30 10

Course No: ENG(IIP): 2- 613 L-T-P-C: 3-0-0-3 Course Title: Chemistry of Lubricants – 3 Credits Coordinating Faculty: Dr. O. P, Khatri List of Faculty: Dr. O. P. Khatri, Dr. R. K. Singh. Course Description Introduction to Lubrication: Fundamentals, Boundary Lubrication phenomena, Lubricants, Types of Lubricants, Base Oils from Petroleum, Bio-lubricants, Synthetic Oils, Ionic Liquids, Solid Lubricants, Lubricant Additives, Antioxidants, Dispersants, Detergents, Rust and Corrosion Inhibitors, Foam Inhibitors, Pour Point Depressants, Anti-Wear Agents and Extreme Pressure Additives, Multifunctional Additives, Formulation of Automotive Lubricants, Automotive Lubricant Specifications, Standard Tests for Lubricants, Lubricant and Environment. ·

Distribution of Lectures

Name Dr. O. P. Khatri Dr. A. K. Chatterjee Dr. S. L. Jain Dr. R.K. Singh Sh. O.P. Sharma (Lab.)

Designation Senior Scientist Chief Scientist Senior Scientist Junior Scientist Technical Assistant

No. of Lectures 20 5 3 8 5

Course No: ENG(IIP): 3- 614 L-T-P-C: 3-0-0-3 Course Title: Automotive Lubricants – 3 Credits Coordinating Faculty: Sh. Devendra Singh List of Faculty: Sh. Nishan Singh, Dr. A. K. Chaterjee, Dr. Manoj Srivastava, Thakre, Sh. S. K. Chibber (External)

Sh. G. D.

Course Description Introduction and Fundamentals of Automotive lubricants; Crude oil Scenario; Vacuum Distillation; Modern refining process; Base oils classifications; characterization of Base oils; Additive types and Significance; Lubricant formulations; Additives for bio-lubricants; Novel additives Introduction to fluid dynamics; Lubrication fundamentals; Characteristics of principal lubrication system; Basics of engine friction; Stribeck curve; Engine friction measurement methods; Application of Reynolds equation for Piston ring assembly friction (PRA); Significance of engine oil consumption; Mechanism of oil consumption; Influence of engine lubricant composition on Oil consumption; Influence of engines on Oil consumption; Types of engine deposits based on temperature; Significance and methodology of Deposit Rating; Rating of engine deposits as per CRC methods Tribological concepts of engine wear; Adhesive, Corrosive and Abrasive wear of Ring/cylinder/Piston; Running-in; Significance of wear metal analysis; Engine lubricant additives requirement Physico-chemical characteristics of engine lubricants; Engine lubricant qualification methodology; Engine Oil Specification (API/ ILSAC/ ACEA/ BIS) and Current performance levels; Engine lubricant’s composition effect on emissions & fuel economy; Introduction to Gears lubricants and greases; Additives requirements for Gear lubricants; Gear Lubricants and Greases additive chemistry, formulations & significance; Gear lubricant specifications and Gear lubricant testing (Standard tests); Grease specifications and current trends; Wear mechanism in gear; Gear distress rating as per CRC ·

Distribution of Lectures

Name Sh. Devendra Singh Sh. Nishan Singh Sh. S. K. Chibber Dr. A. K. Chaterjee Dr. Manoj Srivastava Sh. G. D. Thakre

Designation Scientist Chief Scientist External Chief Scientist Principal Scientist Scientist

No. of Lectures 15 6 5 4 5 5

Course No: ENG(IIP): 3- 615 L-T-P-C: 3-0-0-3 Course Title: Automotive Emissions & Fuel Quality – 3 Credits Coordinating Faculty: Sh. A. K. Jain List of Faculty: Sh. A. K. Jain, Dr. S. K. Singal, Sh. Sunil Kumar Pathak, Dr. B. P. Pundir (External). Course Description Automotive Emissions: Automotive engine types, combustion processes and exhaust emissions from S.I. and C.I. engines, sources of engine/vehicle emissions, emissions and pollutants, photochemical smog, emission formation in SI and CI engines, mechanisms of NOx formation, mechanisms of CO and HC formation, mechanisms of formation of soot and PM, effect of engine design and operating variables on emissions, emission control by engine design variables, crankcase emission control, evaporative emission control, exhaust gas recirculation and water injection for control of engine-out emissions, SI engine exhaust after treatment by oxidation and three-way catalytic converters, advanced catalysts for HC control, lean de-NOx catalysts, NOx storage catalyst, SCR catalysts, catalyst deactivation and poisoning, emission control in CI engines including electronic fuel injection systems, turbo charging, control of oil consumption, diesel oxidation catalysts, NSR and SCR catalyst systems, diesel particulate filters, CRT system, emission norms for various categories of vehicles, summary of trends in emission control technology, air pollution due to automotive exhaust, consequences of greenhouse effect and ozone problem, health impacts of air pollution Automotive Fuel Quality: Motor Gasoline- antiknock quality, distillation, density, RVP, oxidation and storage stability, hydrocarbon composition, sulphur content, oxygenates, reformulated gasoline, trends in gasoline specifications, emission related properties and their effect on exhaust emissions, multi-functional additives and their benefits. Diesel- ignition quality, distillation range, density, viscosity, chemical composition, sulphur content, lubricity, trends in diesel specifications, emission related properties and their effect on exhaust emissions ·

Distribution of Lectures

Name Sh. A. K. Jain Dr. S. K. Singal Dr. B. P. Pundir Sh. Sunil Kumar Pathak

Designation Chief Scientist Chief Scientist Ex. Prof. IIT (External) Sr. Scientist

No. of Lectures 15 10 Kanpur 10 5

Course No: ENG(IIP): 3- 616 L-T-P-C: 2-0-2-3 Course Title: Automotive Test Equipments and Procedures – 3 Credits Coordinating Faculty: Sh. Robindro L List of Faculty: Sh. Robindro L, Sh. Wittison Kamei. Course Description Introduction: Engine testing and Vehicle Testing, Regulated, Un-regulated exhaust emissions, Emission Legislations, Indian Emission regulations, Test parameters i.e. Fuel, Emission Limits. Engine dynamometer: working principles and types, Chassis dynamometers: Control strategy, types and application, Measurement devices and conditioning systems: Fuel balancer, Fuel mass flowmeter, Oil consumption meter, Air consumption meter, Temperature control systems, Smokemeter, Opacimeter. Exhaust emission measurement systems: Raw & Diluted emissions, Classification of analysers (FID,CLD,NDIR,PMD) & their working principles, Portable emission analysers. Dilution systems: Full flow & Partial flow system, Particulate matters (PM) measurement, Engine test procedure: Test cycles, Steady State (13 mode), Transient Cycle (ETC), Load Response (ELR), Particulate Sampling, Vehicle test procedure: Test cycles, Coast down, constant speed test. Calibration of emission measurement systems: analysers, constant volume sampler (CVS), Particulate system, calibration checks for engine dynamometer load cells, chassis dynamometer load cells. Test start and operation: Test flow diagrams, Auxiliary equipments, Test conditions & preparations, Equipment operation, handling and maintenance. PRACTICAL: Engine dynamometer, Smokemeter, Fuel Balancer, Portable emission analyser, emission analysers (FID, CLD, NDIR of old AMA-2000 bench). ·

Distribution of Lectures

Name Sh. Robindro.L Sh. Wittison Kamei

Designation Scientist Scientist

No. of Lectures 20 10

Course No: ENG(IIP): 2- 617 L-T-P-C: 3-0-0-3 Course Title: Alternative Fuels – 3 Credits Coordinating Faculty: Sh. S. K. Pathak List of Faculty: Dr. S. K. Singal, Sh. S. K. Pathak, Sh. Vijayanad, Dr. Neeraj Atrey, Dr. Anil Sinha. Course Description

Overview of Energy, Global and Indian energy scene, fuel resources and environmental policies; Conventional Fuels: Introduction, liquid and gaseous fuels and desirable properties of good IC engine fuels; Alternative fuels- General aspects, type of fuels and technical and policy challenges. Alcohols: Methanol and Ethanol - Production, properties and application in engines, Ethanol and Gasoline blends and its application in vehicles, Ethanol and diesel blends and its application in C I engines; Butanol - Production, its application in SI and CI engines; Vegetable oils: Production and its application as I C engine fuel; Bio-diesel- Production and its properties; Bio-diesel- Application in engines/vehicles, F T diesel. LPG: Conventional and new techniques of Production, Domestic and automotive fuel Properties, conversion system and technological advances, engine modifications, Regulatory codes, Performance and emissions, safety issues. Natural gas: Conventional and new techniques of Production, Automotive fuel properties, gas conversion system, First generation to third generation, engine modification, Regulatory codes, Performance and emissions, safety issues. Hydrogen: Conventional and new techniques of Production, properties, Induction Techniques for Hydrogen application in SI engines and CI engines; H2+Natural gas(HCNG), HCNG Properties; HCNG- conversion system; Regulatory codes; HCNG: Performance and emissions. Bio gas: Production and Properties, Bio gasApplication in engines/vehicles, NH3- Production and properties; NH3- Application in engines/vehicles, Producer gas- potential as I C engine application. DME: Production and properties, DME application in engine and technical issues and review of the work research and development carried out in the world Alternative energy application for propulsion: Electrical vehicles, Hybrid vehicles, solar energy and solar powered vehicles, Fuel cell basics and type of fuel cells, Fuel cell vehicles. Miscellaneous: Alternative fuel powered vehicle evaluation as per Tap document, CMVR: Laboratory methods, Field Tests, Future Policy frame work for Alternative fuelled vehicles, Comparison of different alternative fuels based on vehicle usage and economics ·

Distribution of Lectures

Name Dr. S K Singal Sh S K Pathak Sh Vijyanand Dr. Neeraj Atray Dr Anil Sinha Sh S K Pathak(Lab.)

Designation Chief Scientist Senior Scientist Principal Scientist Senior Scientist Principal Scientist Senior Scientist

No. of Lectures 5 14 7 7 2 5

Course No: ENG(IIP): 2- 594 L-T-P-C: 3-0-2-4 Course Title: Renewable Energy Conversion Technologies – 4 Credits Coordinating Faculty: Dr S Kaul List of Faculty: Dr. S. Kaul, Dr. T. Bhaskar, Dr. D. K. Adhikari, Dr. A Sinha, Dr. Ajay Kumar, Dr. Neeraj Atrey, Sh. D. V. Naik, Sh. Dinesh Bangwal.

Course Description Introduction to renewable energy technologies; Energy scenarios and perspectives - past, present and future Non-renewable and renewable energy sources; description of renewable sources and their importance, current status, potential and future trends, renewable energy options for immediate and future directions. Technologies for biomass energy conversion i.e., pyrolysis, gasification, combustion, trans-esterification; fermentations, thermo-chemical conversions, value-added products from pyrolysis, thermal and catalytic methods for the upgrading of biomass; bio-refining products and applications. Solar energy sources, measurements, interconversions; Passive solar - architectural design, solar collectors; Solar energy conversion - photosynthesis and artificial photosynthesis; Photo-voltaicsemiconductor properties, performance criteria, manufacturing, economics; PV systems - installation, data collection and analysis. Historical background of wind resources - wind speeds and wind energy principles; Wind Turbines - system components, Environment Impact on applications. Ocean energy potential against wind and solar; Wave characteristics and statistics; Wave energy devices; Tide characteristics and statistics; Tide energy technologies; Ocean thermal energy; Osmotic power; Ocean bio-mass Geothermal Resources; Geothermal Technologies; Applications; Sustainable sources of hydrogen; Fuel cell technologies; Hydrogen storage and distribution; Applications and feasibility assessment; Science, technology and policy of energy conservation; Strategies for enhancing role of renewable energy. · Distribution of Lectures Name Dr. Savita Kaul Dr. T. Bhaskar Dr. D. K. Adhikari Dr. Anil Sinha Dr. Ajay Kumar Dr. Neeraj Atray Mr. D. V. Naik (Lab.) Sh. Dinesh Bangwal (Lab.)

Designation Principal Scientist Senior Scientist Chief Scientist Principal Scientist Scientist Senior Scientist Scientist Senior Technical Officer 3

No. of Lectures 12 7 5 3 3 3 3 4

Course No: ENG(IIP): 1-001 L-T-P-C: 1-0-0-1 Course Title: Research Methodology – 1 Credits Course Description Introduction; Research terminology and the scientific methods; Laboratory practices, discipline and safety practices; Types of Research; Research process and steps; Identifying a research problem; Literature survey and appreciation of existing literature; Conception of novel approach to solve the problem; Role of modelling and simulation; Design of experiment; Quantitative methods of data analysis; Qualitative analysis; Communicating Research results; Ethics in research. Case studies

CSIR-IMMT ENGG (IMMT)-1-001: Research Methodology: 2-0-0-2 1.

Research Methodology - Introduction · Meaning, Concept, Need · Historical Research · Survey Research · Experimental Research · Fundamental and Applied Research

2.

Literature Search & Review of Literature

3.

Research Tools · Measurement of Variables · Presentation of Data · Statistical Techniques – All Basic Techniques, Null hypothesis, Error Analysis, Interval estimation, Statistical Significance, Examples: Analysis of variance (ANOVA), Chi-squared test, Correlation, Factor analysis, Mann–Whitney U, Mean square weighted deviation (MSWD), Pearson product-moment correlation coefficient, Regression analysis, Spearman's rank correlation coefficient, Student's t-test and z-test, Time series analysis · Statistical Packages: o MS Excel - Introduction, Getting Data into Excel, Activating the DataAnalysis Tools, Using Excel to Determine a Confidence Interval, Using Excel for t-Tests of Hypotheses, The t-Test for Independent Samples, The t-Test for Dependent (and Matched-Pair) Samples, Using Excel for ANOVA, Using Excel for Correlation, Using Excel for Linear Regression, Using Excel for Chi-Square Tests, The Chi-Square Goodness-of-Fit Test and the Chi-Square Test of Association o MATLAB - Introduction and Key Features, Developing Algorithms and Applications, Analyzing and Accessing Data, Visualizing Data, Performing Numeric Computation, Publishing Results and Deploying Applications

4.

Research Types and Methods · Observation Method · Questionnaire Method · Interview Method · Experimental Method

5.

Research Process · Designing a Research: Characteristics, Purpose · Research Plan · Analysis and Testing · Quantitative Methods and Data Analysis · Qualitative Analysis

6.

Communicating Research Results · Journal paper · Thesis · Project proposal · Report · Web publishing · Seminar and Oral presentations

7.

Research Ethics and Plagiarism

8.

Case Studies

Course Instructors: Dr. D.B. Ramesh, Dr. D. P. Sandha, Dr. D.P. Das ENGG (IMMT)-2-626: Computational Methods & Numerical Analysis: 3-0-2-4 Computation & Programming: Notions of syntax and semantics of programming languages, Concept of algorithm, Systematic development of programs, Computer Architecture & Memory management, Object Oriented Programming & Data structure, parameter passing mechanisms, Program design practices.

Numerical Scientific Computing: Numerical differentiation & integration, Solving polynomial equations, Computational matrix, Transforms

Computer Graphics: Input / Output devices, Raster & Vector Graphics, Drawing algorithms; Windowing and 2D/3D clipping. 2D & 3D Geometrical Transformations, Viewing Transformations, Animation Techniques

Statistical Analysis: Statistical Concepts, Conditional Probability and independence, Regression Analysis, Design of Experiments, Support Vector Machine, Statistical Inference, Optimisation.

Practical/ Lab Work: Statistical Analysis using standard statistical package, application modelling using MATLAB, application programming practices with standard graphics libraries like open GL.

Course Instructors: Dr. D. P. Das, Mr. S. Rath

ENGG (IMMT)-2-627: Technologies for Mineral Resource Utilization: 3-0-2-4 Particulate technology, particle size distribution, sizing methodology, size-reduction and classification processes; Particulates in suspension, stability, Rheology and settling; Solidliquid separation methods; Physics, chemistry, and engineering design as applied to gravity, magnetic, electrostatic, and froth flotation processes Course Instructors: Mr. P.S.R. Reddy, Prof. D.D. Misra, Prof. B.K. Mishra ENGG (IMMT)-2-628: Materials Characterization Technique: 3-0-2-4 Size and surface area analysis; Interaction of X-rays with matter, diffraction techniques and applications; Optical principles of microscopy; electron diffraction, imaging (various contrasts), determination of crystal structure, burgers vector, electron beam-specimen interactions and other applications of Transmission Electron Microscopy; Applications of Scanning Electron Microscopy and, Electron Probe Micro-Analyser; Principles of Quantitative Microscopy: Overview of other characterization techniques such as Auger electron spectroscopy, Scanning Tunneling Microscopy, Atomic Force Microscopy. Course Coordinator: Dr. B. K. Mahapatra ENGG (IMMT)-2-629: Recycling of Material Resources: 3-0-2-4

Mining and metallurgical wastes classification, investigation and evaluation of waste deposits, waste and circulatory management during recycling. Unit operations involving materials recycling processes such as pre-treatment (physical and chemical), roasting, calcination, sintering, leaching, solid-liquid separation; Solution, concentration and purification techniques—precipitation, cementation, solvent-extraction, evaporation, crystallization, electrowinning, electroremediation; Resources and recycling technologies across the major materials sectors, and case studies including wastes in steel and aluminium production; Recycling of E-wastes and secondaries; Economic evaluation and project implementation: Flow-sheet development, mass and energy balance, costing, technoeconomic feasibility report (TEFR) preparation, financial investment in waste recycling, project planning and implementation, work safety. Course Coordinator: Dr. K. Sanjay ENGG (IMMT)-2-630: Process Instrumentation & Control: 3-1-0-4

Introduction to instrumentation in process industry, Different types of sensors and actuators, Computerized data acquisition, Monitoring and analysis of data (Time series and spectral analysis), Process control, PID Control, Introduction to PLC, SCADA & DCS, Networking and communication in industry, Artificial neural network & Fuzzy logic based control, Laboratory work. Course Coordinator: Dr. D. P. Das ENGG (IMMT)-2-631: Science for engineers: 3-0-0-3

Concepts of atomic and molecular energy levels leading to description of plasma state, plasma physics—thermal and non-equilibrium plasma, plasma diagnostics, methods of plasma processing of materials and minerals; Industrial plasmas, new concepts of resource utilization using plasma, Crystal structure and defects, electron and hole in lattices, Band gap module and tailoring : -optical and electrical, variable band gap. Structure and Bonding; Molecular basis of chemical reactions, reaction kinetics, structural effect on reactivity; Complexation concepts, Spectroscopy, Metals in biological domain, Molecular engineering; Computational approaches for structure-function correlation, Surfaces and interfaces, Chemical theories involved in solution, concentration and purification, Micelles, surfactants and their application for bulk processing of mineral resources. Cell types structure and function; Bio-molecules: composition and bonding; Overview of amino acids, proteins, carbohydrates, nucleic acids, lipids, enzymes, vitamins and minerals; DNA replication; Membranes, Introduction to bio-mineral processing. Course Coordinator: Dr. Bikash K. Jena ENGG (IMMT)-2-632: Fundamentals of Engineering Analysis: 3-0-0-3 Fundamental concepts of fluid flow, heat and mass transfer; Shell balance approach for molecular and convective transport processes; Formulation and solution of ordinary and partial differential equations that describe physical systems of importance in engineering; some applications to minerals and materials processing Numerical methods: finite difference, numerical solution of ordinary and partial differential equations. Course Instructor: Dr. Swati Mohanty

ENGG (IMMT)-2-633: Process Design & Simulation: 3-0-2-4

Preliminary resource evaluation methods; Identification and development of process flow sheet; Elementary evaluation of plant performance; Spread-sheet development for plant data analysis; Introduction to simulation environment using MODSIM, simulator structure, numerical analysis of simulation, sequential method of simulation, practical application of plant simulation; Materials and energy balance, mass balance smoothing, data reconciliation in terms of grade and recovery, analysis of complex flowsheet for mass balancing, examples of material balance smoothing; Application of modeling and residence time distribution concepts for plant data interpretation; Parameter estimation: linear regression, one, two, and multi-linear regression; models nonlinear in parameters; Case studies of typical process plant design and operation. Course Instructors: Prof. B. K. Mishra, Dr. C. Eswariah ENGG (IMMT)-2-634: Advanced Extraction Methods: 3-0-0-3 Fundamentals of commercially important nonferrous pyrometallurgical extraction processes; Thermodynamics of high-temperature processes and solid-gas reaction kinetics; Heterogeneous kinetics, multi-phase systems, Electrodics, Semiconductor electrochemistry; Application: roasting, sulphide-oxide-sulphate systems, oxide-chloride systems, smelting, kinetic analysis, bath smelting, dynamic contact angle-free energy correlation; Electrosmelting—present practice and future trends; Direct electrowinning, possible electrode systems, conduction types, future trends. Course Instructor: Dr. R. K. Paramguru

ENGG (IMMT)-2-635:Advanced Topics in Materials Resource Engineering:3-0-2-4 Plasma Processing Introduction, Basic plasma and gas discharge concepts, Glow discharge plasmas, Thermal plasmas, Plasma torches and sprays, Plasma chemistry, etching and polymerization, Plasma coatings, Diamond and diamond-like films, Diagnostics/Probes, Plasma Spraying, Preparation of nano powders, Plasma smelting, Plasma sintering Powder Metallurgy

Production of metal and alloy powder, particle size & shape, microstructure, Powder compaction, Sintering (Solid state sintering & Liquid phase sintering), Hot pressing, Sintering furnaces & atmospheres, Applications of powder metallurgy. Corrosion Science & Engineering General introduction, Electrochemical reactions, Thermodynamic concepts, Eh-pH diagram, Prevention of corrosion Rheology Fundamentals, Types of viscometers and rheometers, Applications Course Coordinator: Dr. S.K. Singh

ENGG (IMMT)-2-636: Energy & Environment: 3-0-2-4

Important Indian minerals & related environmental issues; Environmental impact due to mining in Orissa; Case study on graphite resources of Orissa and environmental management, Environmental issues related to mining, processing and products – solid wastes, Environmental impact analysis and management plan, Case studies related to environmental management of minerals and materials industries; Effluent treatment (nutrients removal ) through microbial activity, Vulnerability and adaptation technologies for sustainable development, Pollution generation and management – Effluents, Environmental laws and global issues related to environment, Conservation of energy in different production and processing steps, Energy audit in mineral and material processing industries. Course Coordinator: Dr. B. C. Acharya

ENGG (IMMT)-2-637: Mineralogy and Mineral chemistry: 3-0-2-4) Process mineralogy, Liberation Studies using QEMSCAN, Mineral chemistry using EPMA, Identification of mineral phases through XRD. Geochemistry :Chemical composition of the Earth, elementary statistics for geochemistry; major, minor and trace elements including rare earth elements; element partitioning between minerals and melts; petrogenesis, Geochemical Classification of elements, Geochemical differentiation, Isomorphism, Polymorphism, Atomic substitution and Geochemical cycle. Analytical Geochemistry: Chemical analysis of rocks and minerals, digestion techniques, preparation of standards, estimation of major oxide percentages using spectrophotometric /flame photometric and titrimetric methods. Preparation of calibration curves. Gravimetric estimation of silica and R2O3. Determination of noble metals. Introduction to Neutron Activation Analysis, principles of ICP, XRF & AAS analysis.

Statistical Methods in Geosciences: Introduction to probability: random experiments, events, sample space, definitions of probability. Conditional probability and independence of events, Bayes theorm. Random variables, discrete and continuous probability distributions, joint probability distributions, conditional probability distributions. Mathematical expectation, moment generating and characteristic functions. Binomial, Poisson, Normal, Gamma, Exponential, Hypergeometric, Multinomial, Chi-square, t, and F distributions. Introduction to statistical inference, sampling distributions, point and interval estimation, hypothesis testing involving one and two univariate populations. Linear models ANOVA. Linear and multiple regression. Introduction to multivariate techniques PCA, factor analysis, linear discriminant analysis, classification

ENGG (IMMT)-3-626: Computational Fluid Dynamics: 3-0-2-4 Introduction to Computational fluid dynamics; Conservation equations: momentum, energy and mass balance equations; Discretization methods: Finite difference method, Finite element method, Finite volume method; Structured and unstructured grid; Multiphase flows: fluid-fluid, fluid-solid; Turbulence modeling: Direct Numerical Simulation, Large Eddy Simulation, Reynolds Averaged Navier Stokes model; CFD modelling of some mineral and material processing unit operations; Introduction to CFD software. Course instructor: Dr. Swati Mohanty

ENGG (IMMT)-3-627: Advanced Materials: Characterization and Processing: 3-1-2-4

Theory: Fundamentals of crystallography, crystal structure and structure determination by XRD, electron diffraction and neutron diffraction in polycrystalline materials, stereographic projection and pole figures, orientation and texture analysis, structure of metals, alloys, solid solution, concept of amorphous, glassy and nano materials and their characterization, defects in crystals, theory of dislocation, Burger vector, plastic deformation, stress measurement by XRD, strengthening mechanism, cold working and heat treatment of steel, hardness and tensile test of steel, concepts in fracture mechanics and fracture determination methods, S-N curve, low cycle fatigue, fatigue mechanism. Practical: Study of types of high temperature furnaces including plasma furnace, induction and vacuum induction furnace, study and determination of vacuum in rotary and diffusion pumps, high temperature determination by thermocouple and pyrometer, morphology and microstructure observation by various microscopy methods (SEM, TEM, AFM, optical), XRD, Raman spectroscopy and identification of impurities and precipitates in metals,

microhardness and nanoindention measurements, tensile, fracture toughness and fatigue tests of steel. Course Coordinator: Dr. B. B. Nayak

CSIR-National Chemical Laboratory Eng(NCL)1-001: Research Methodology

2-0-0-2

2 credits

Course Objective To review data analysis fundamentals, teach common research techniques from literature survey and organization to effective communication, ethics, lab safety practices. Modules · Scientific literature survey and reference management · Scientific writing and presentation · Intellectual Property Management · Ethics in Science · Maintenance of lab records · Lab safety and first-aid · Quantitative methods and data analysis Eng(NCL):1-003: Numerical Methods and Programming

3-0-0-3

3 credits

Course Objective To understand the algorithms involved in the numerical methods used for computer simulation, have the ability to choose an appropriate algorithm and be aware of the advantages and pitfalls expected in a particular algorithm. Computer implementation of algorithms and use of Matlab or other subroutines. Modules · Introduction to Programming, linux, introduction to Matlab/Scilab/Octave · Matrix operations · Function approximations, solutions of system of nonlinear equations · Numerical methods for ODEs · Finite-difference/volume methods for PDE · Optimization approaches

Eng(NCL):1-701: Mathematical fundamentals

3-0-0-3 3 credits

Course Objective To review mathematical fundamentals, teach common mathematics prerequisites of other courses, and to impart perspective on modeling and simulation. Modules · Analysis basics · Linear Algebra · Ordinary and partial differential equations · Optimisation

Eng(NCL):1-702: Reaction and Reactor Engineering

3-0-0-3 3 credits

Course Objective To develop the understanding of the reactions from molecular scale to the reactor scale, and to equip the student to model different reactor configurations and non-idealities in reactor systems. Modules · Chemical kinetics · Homogeneous reactor analysis and design · Heterogeneous reactor analysis and design · Special reactors

Eng(NCL):1-703: Transport phenomena

3-0-0-3 3 credits

Course Objective To develop a good physical understanding of the processes of momentum, heat and mass transfer at the continuum level; to develop the mathematical tools to solve problems in transport phenomena Modules · Linear algebra and calculus relevant to transport phenomena · Conservation equations · Examples in transport phenomena Eng(NCL):1-704: Thermodynamics and Statistical Mechanics

3-0-0-3 3 credits

Course Objective To develop the understanding of thermodynamics principles as applicable to chemical systems. Modules · Classical Thermodynamics, ideal gases · Solution thermodynamics · Equilibrium thermodynamics · Non-equilibrium thermodynamics · Ensemble methods Eng(NCL):2-711: Multiscale simulations in materials

3-0-0-3 3 credits

Course Objective To be familiar with simulations at the molecular and sub-molecular scale, including quantum chemistry based and classical mechanics based methods. Modules · Introduction to molecular modeling · Quantum-chemistry driven modeling · Classical mechanics based modeling

·

Example problems at multiple scales

Eng(NCL):2-712: Industrial flow modeling

3-0-0-3 3 credits

Course Objective To teach students the basic equations of fluid dynamics and computational methods to solve these equations as applied to flows in industrial processes. At the conclusion of the course students will be able to analyze complex flow situations, develop a simple model for complex flow and solve it numerically, and simulate the actual complex flow using available CFD software. Modules · Introduction to CFD · Solution techniques for solving CFD equations · Introduction to CFD Software · Turbulence modeling · Multiphase flows Eng(NCL):2-713: Data driven modeling

2-0-0-2 2 credits

Course Objective The course will emphasize the conceptual understanding of methods along with their implementation in real world scenarios. At the end of the course, the student is expected to be able to identify and implement appropriate conventional, machine learning or AI based methods for linear/non linear data fitting, data reduction, and classification. Modules · Statistics basics · Supervised learning · Unsupervised learning · Artificial intelligence based methods · Model validation · Practical applications in data reduction, feature selection, classification. Eng(NCL):2-714: Non-linear dynamics

3-0-0-3 2 credits

Course Objective Introduce methodologies for analyzing complex nonlinear behavior with examples from reaction engineering, chemical, and physical systems. Students will learn (1) how nonlinear systems differ from linear systems regarding their dynamical properties; (2) how to analyze the stability of complex systems ; (3) how sensitivity of system dynamics is related to predictability and control; (4) to explore dynamical systems analytically and with computer simulations Modules · Introduction to the dynamics of nonlinear systems · Preliminary analysis of time-series data: · Toy “Nonlinear models” and the role of parameters · Stability of solutions to ODEs · Properties of chaos: · Self organizing properties of nonlinear systems

·

Phase space analysis

Eng(NCL):2-715: Modeling of biological systems

3-0-0-3 3 credits

Course Objective Provide a brief background of biological systems for model development. Bioreactor design and analysis. Metabolic network modeling using constraint based approaches and signaling pathway modeling using deterministic and stochastic modeling techniques. Modules · Biological fundamentals · Bioreactor models · Metabolic pathways · Signaling pathways · Pharmacokinetics and pharmacodynamics

Eng(NCL):2-716: Advanced separation processes

2-0-0-2 2 credits

Course Objective Provide understanding of the principles underlying various separation processes. Modules · Mass transfer and thermodynamics applications to separations · Unit operations in separation: adsorption, distillation etc · Fundamentals of separation equipment design Eng(NCL):3-701: Advanced topics in materials and processes

2-0-0-2 2 credits

Course Objective An in-depth study of specific topics well beyond material available in textbooks. As appropriate, it may include specialized training on high-end equipment that is not normally part of a MTech level lab course. Eng(NCL):3-702: Advanced topics in chemical engineering 2-0-0-2 2 credits science Course Objective An in-depth study of specific topics well beyond material available in textbooks. Envisaged as a discussion of recent papers and projects on areas extending the currently published work. Eng(NCL):2-701 to 2-704: Lab courses

0-0-4-2 2 credits

Course Objective Training in planning, executing, analyzing and reporting results from an experimental study in several disciplines, ranging from introductory experiments to advanced training in use of sophisticated equipment.

Eng(NCL):2-696 to 2-699: Seminar Participation

0-1-0-1 1 credit each

Course Objective Provide exposure to current research and societal activities through talks by eminent scientists and other speakers. Students will be required to attend approximately 10 talks every semester. Research Proposal I and Research Proposal II

0-0-4-2 credits

02 x 2 =4

Course Objective State-of-the art review, methodologies, recommendations etc. for two topics of high relevance and novelty Eng(NCL):2-700: Symposium participation

0-0-2-1 01 credit

Course Objective Provide exposure to current topics through scientific talks and poster session, and an opportunity to showcase research ability and results to potential employers. Students are expected to present posters and interact with participants from industry and academia. Eng(NCL):3-699: Critical survey

0-0-4-2 02 credits

Course Objective State-of-the art review, methodologies, recommendations etc. for topic related to thesis research.

CSIR-SERC Campus (2-0-0-2) ENG(SERC): 2-930: Renewable Energy Sources for a Sustainable Future Course coordinator: Dr. Bala Pesala 2 Credits Faculty: Dr. Saptarshi Sasmal, Shri. K. Srinivas, Dr. Carmalin Sophia The course provides a brief overview of the field of the renewable energy covering scientific, technological and pricing aspects. Course Content: • • • • • • •

Basic thermodynamics: Laws of thermodynamics, Energy and entropy, Carnot efficiency Non-renewable sources and climate change discussion Introduction to various renewable technologies (solar, wind, hydro, geothermal etc.) Decentralized hybrid power: Need and potential in Indian context Instrumentation and sensors for power monitoring Structural Design basics: Engineering mechanics Energy costing and comparison with non-renewables

ENG(SERC): 2-931: Harnessing the power of Sun: Science and Technology of Solar Photovoltaics Course coordinator: Dr. Bala Pesala Solar photovoltaics shows the biggest promise to solve the energy crisis. This course provide a solid scientific base for understanding and designing various solar cells experience to test and evaluate the performance of solar cells.

(3-0-2-4) 4 Credits is designed to and hands-on

Course Content: • • • • • •

Solar cell introduction: Shockley-Queisser limit, efficiency Introduction to semiconductors: Direct/Indirect band gap semiconductors, Energy band structure of solids and band diagrams Basic semiconductor electronics: p-n junctions, diodes, transistors, heterostructures Quantum mechanics: Schrodinger equations, Kronig-penny model, Quantum potential wells Detailed discussion of various solar PV technologies (Si, Thin film, GaAs etc.) Design and simulation of solar cells

Lab: • •

Solar cell design using TCAD/Matlab Testing and characterization of solar cells (Si, Multijunction, Thin film) (Current-voltage characteristics, efficiency)

ENG(SERC): 2-932: Energy Storage and Conversion: Science & Technology Course Coordinator: Dr. A. S. Prakash Faculty: Dr. S. D. Bhat, Dr. K. Ramesha, Dr. A. K. Sahu

(3-0-2-4) 4 Credits

This course will cover introduction, basic principles and science & technology of various energy storage and conversion systems Course Content: • • • • • • • • •

Introduction to energy storage: thermal, mechanical, compressed air, pumped hydro & chemical energy. Electrochemical energy storage: Batteries, super capacitors and fuel cells Battery basic concepts: Cell voltage, capacity, energy/power density, primary and secondary batteries, thermodynamics, working principles, electrode process. Battery types: Lead acid, Ni-Cd, Nickel-metal hydride, lithium ion. Batteries for EV, solar applications and recent advances. Dye-sensitized solar cells Fuel cells: Types of fuel cells, materials & components, applications, thermodynamics, kinetics, system design and engineering, hydrogen storage. Dye sensitized solar cells: Comparison of various energy storage systems, cost economics, market trends Lab:

• •

Fuel cell stack fabrication, assembly & testing, General electrochemical characterization, cyclic voltametry, chronoamperometry, half-cell studies.

(1-1-0-2) ENG(SERC): 1-002: Mathematics for Engineers Course Coordinator: Dr. Madan Kumar Lakshmanan 2 Credits This is a refresher program that provides an overview of mathematical fundamentals essential to grasp the advanced concepts of renewable energy engineering. It is devised to impart key mathematical skills to students from diverse disciplines and expose them to various numerical/computational tools. Course Content: • Linear algebra: Matrices, system of linear equations, linear transformations, vectors, vector spaces, inner product spaces, Eigen vectors and eigen values, orthogonal projection. • Transforms: Fourier series, Fourier transform (FFT, DFT, DTFT), Laplace transform, Ztransform, Wavelet transform, Karhunen–Loève theorem. • Differential equations: Introduction to differential equations, first/second order differential equations, Partial differential equations, geometrical interpretation • Integrals: Definite integrals, indefinite integrals, line and surface integrals, integrals of differential forms. • Sequences and series: convergence of series, finite and infinite series, Taylor and Laurent series expansions. • Mathematical and computational tools: Matlab, Mathematica

(1-0-0-1) ENG(SERC): 2-933: "View from the TOP" Seminar Series I Course Coordinator: Dr. Bala Pesala 1 Credit Seminar aims at giving exposure as to how the best quality science is pursued, what drives the scientists and their experiences in overcoming various hurdles during their scientific pursuit • •

Talks by leading scientists in CSIR Invited talks by various professors on specialized topics in energy

Invited speaker list*: Dr. Samir Brahmachari , DG, CSIR Dr. Nagesh Iyer, Director, CSIR-SERC Dr. Chandra Shekhar, Director, CSIR-CEERI Dr. Ehrich Desa, Director, CSIR 800 Prof. Connie Chang-Hasnain (Professor, UC Berkeley) Prof. Eli Yablonovitch (Professor, UC Berkeley) Prof. P.C. Ku (Professor, University of Michigan) Prof. Tonio Buonassisi (Professor, MIT) Dr. Arun Majumdar (Director, ARPA-E, U.S.A) Prof. Ramesh Ramamoorthy (Director, Sunshot Initiative, DOE, U.S.A) Prof. Anand Veeraraghavan, University of Queensland, Brisbane, Australia (1-0-2-2) ENG(SERC): 2-934: Design and Engineering for Sustainability Course Coordinator: Dr. Saptarshi Sasmal 2 Credits Faculty : Dr. Prabhu Rajagopal (IIT Madras) This course provides a generic overview of the principles needed for the design and engineering of various systems and products. Course Content: •

Design approaches • Multi-objective design • Design optimization • Metrics for design evaluation • Design for ‘X’ • Manufacturing and assembly • Ergonomics • Inspectability and sustainability • Practical aspects of design • CAD • Manual prototyping • Automated prototyping (3D printing/Rapid prototyping) Lab: Solve a design problem with a given constraints Ex: Solar lantern that can replace a kerosene lamp at a competitive cost (1-0-0-1) ENG(SERC): 2-935: "View from the TOP" Seminar Series II Course Coordinator: Dr. Bala Pesala 1 Credit Seminar to expose students to the real problems in the energy sector and the need for innovative technological solutions, unique business models to make renewable energy sustainable especially in a decentralized setting and for people at the BOP •

Talks by various entrepreneurs and executives from industry working in renewable energy

Invited speaker list*: Dr. Harish Hande, SELCO, India Dr. Bunker Roy, Founder, Barefoot college, Tilonia

Mr. Anshuman Lath, CEO, Gram Oorja Mr. Sai Baba, Lanco Solar Mr. Carlos Treves, High-flex solar, U.S.A Dr. Nasreen Chopra, Altadevices, U.S.A Dr. Bernardo Costanova, LS13, U.S.A ENG(SERC): 3-930: Solar Photovoltaics: Power Electronics, Power Transmission (3-0-2-4) 4 Credits and Energy Monitoring Course Coordinator: Dr. Bala Pesala Faculty: Shri. K. Srinivas, Shri. Suriya Prakash, Shri. G. S. Aiyappan Utilization of solar photovoltaic energy for various applications requires appropriate power conversion devices/electronic systems and instrumentation for real time monitoring. This course provides an indepth understanding of these fields. Course Content: • Power electronics: Power devices (BJT's, MOSFETs, IGBT's) · Microcontrollers/Embedded controllers, Charge controllers · Inverters and rectifiers · Control systems (active/passive controls), Maximum power point tracking · Single/dual axis tracking systems: Design and implementation · Sensors and instruments for monitoring: Power, Voltage, light intensity, Battery charging/discharge cycles · Remote monitoring: Wired/wireless/Power line, Wireless technologies (GSM/Wi-fi/Zig-bee) and smart power meters · Smart grid systems: Transmission (AC/DC), Grid connection topologies/super grids for renewable energy, HVAC-HVDC cost analysis and utility Lab: · · · ·

Solar module performance monitoring MPPT design and implementation Matlab toolbox for sensor and instrument progamming and monitoring Remote monitoring using Zig-bee communication

(3-0-2-4) ENG(SERC): 3-931: Advanced course on Lithium-Ion Batteries Faculty: Dr. K. Ramesha , Dr. A. S. Prakash 4 Credits This course gives concise understanding of electrochemistry and comprehensive knowledge on Lithium-ion batteries with detailed understanding of components and materials chemistry. The course also involves complete understanding of various characterization tools used in materials science such as XRD, SEM, TEM and electrochemical analysis. Hands on experiments are formulated to cover all aspects - from synthesis, characterization to complete assembly of Li-ion battery cells. Course Content: · · · · · ·

Introduction to batteries: Historical perspective, Kinetics/thermodynamics/charge transfer process, Faraday’s law of electrolysis, standard cells and electrode potentials Lithium battery active materials: Anode: intercalation, conversion, alloying; Cathode: Layered, framework structures Electrolytes: organic, polymeric, ionic liquids. Aprotic organic electrolytes, Polymer electrolytes-dry, gel and composites, polymer membranes. Separators: materials, properties, porosity, thermal, mechanical and electrochemical stability. Safety, assembly and recycling Synthesis approaches for battery materials and crystallography

·

Instrumental methods in Li-ion battery research: XRD analysis, microscopy (SEM, TEM), thermal analysis (TGA, DTA, DSC), IR, Raman analysis, GITT, impedance analysis etc.

Lab: · · ·

Li-ion battery fabrication, material preparation (cathode, anode). Materials characterization (XRD, SEM, TEM, TGA, etc). Electrochemical tests on Li-ion batteries (CV, charge-discharge, capacity, life cycle studies, GITT, EIS).

(2-1-2-4) ENG(SERC): 3-932: Design of Structures For Renewable Energy Course Coordinator: Dr. Saptarshi Sasmal 4 Credits Faculty : Dr. J. Rajasankar, Dr. P. Harikrishna, Shri. G. Ramesh Babu The course is aimed at enabling the scholars to conceptualise, analyze and design structures for renewable energy sources such as solar and wind, specifically, the solar PV modules and wind turbines. Course Content: · ·

· · · ·

Fundamentals of Structural Mechanics: Introduction to structural mechanics, Kinetics, Kinematics and Energy theorems FEM techniques for structural analysis: Stationary principles, Rayleigh-Ritz method and interpolation, Iso-parametric finite element, shape function, modeling, numerical integration, coordinate transformation Design Concepts: Limit states, LRFD, fatigue for concrete/steel/composite structures Support structures for solar photovoltaic modules: Loads and analysis, design Support structure for wind turbines - Loads and analysis, design of superstructure and foundation Wind turbine blades: Stress analysis and design

Lab: · · ·

Structural form effect FEM applications Wind tunnel-scaled modelling of structures

(3-0-2-4) ENG(SERC): 3-933: Bio Energy: The Plants Work & Let Us Reap Course Coordinator: Dr. Carmalin Sophia 4 Credits Faculty: Dr. Rima Biswas Bioenergy module is developed keeping in mind the energy sectors imminent and future need for personnel with green energy skills. The module provides an introduction to the Bio-energy, sustainability, issues and framework required appreciate the significance of bio-energy related matters with and industrial environment Course Content: · · · · · · · ·

Introduction to bio-energy Bio-energy sustainability: Land use, bio-energy crops, feed stocks Agronomy of bio-energy crops, Environmental implications Chemistry & biochemistry of Biomass Biochemical processes (conversion, deconstruction, bio-processing) Bio-fuels (ethanol, bio-butanol, biodiesel, cellulosic and other biofuels) Physical and chemical processes (combustion, gasification, pyrolysis) Direct biomass combustion & Co-firing technologies Power generation from bio-mass

and crop harvesting,

· ·

Economics of bio-energy (costs, prices, markets, financing and marketing Policies & Future R&D of Biofuels & Bioenergy

Lab: · · · · ·

Microbial conversion of plant derived biomass into bio-fuels Pre-treatment technologies to make the lignocellulose more accessible to enzymes, hydrolysis of polysaccharides to sugars, conversion to a fuel molecule, and extraction of the fuel Microbial fuel cell/ Microbial electrolysis cell, Microalgal biofuels Thermo-chemical, chemical and catalyst conversion of biomass/Gasification Bio-energy systems engineering

(1-0-0-1) ENG(SERC): 1-930: Effective Presentation Skills and Dissertation Writing Course Coordinator: Dr. Bala Pesala 1 Credit This course teaches effective presentation skills and valuable tips on dissertation preparation and writing. ENGG(SERC) 1-906: Instrumentation & Sensors for Structural Response Measurement

(L-T-P-C) : 3-0-2-4

Faculty : Shri K. Srinivas ( CSIO), Dr. K. Ravisankar, Dr. S. Arunachalam Introduction: Definition of Instrumentation, Why instrumentation of Structures/Structural components? concepts and Methods - Potential areas of application; measurements: Data Acquisition - Data Transmission - Data Processing - Storage of processed data - Knowledgeable information processing - Remote Structural Health Monitoring; Sensors for measurements: Electrical Resistance Strain Gages (ERSG), Vibrating Wire Strain Gages (VWSG), Fiber Optic Sensors (FOS), Temperature Sensors, Accelerometers, Displacement Transducers, Load Cells, Humidity Sensors, Crack Propagation Measuring Sensors, Corrosion Monitoring Sensors, Pressure Sensors

ENGG(SERC) 1-907 : Advanced Mechanics of Materials Faculty : Dr. Nagesh R Iyer , Dr. G.S. Palani

(L-T-P-C) : 3-0-0-3

Concept of Stresses and Strains - Basic Concepts, Mechanical Behaviour of Materials, Stress and strain tensors, Thermal Stresses; Mechanical Properties of Engineering Materials - Stress-Strain Curve of Engineering Materials, Constitutive relations ; Solid Mechanics Approach - Principal Stresses and Strains, Axially Loaded Members, Plane stress, Plane Strain and Axisymmetric Problems, Closed and Open Coiled Helical Springs, Strain energy, Introduction to concepts of plasticity ; Bending and shear of beams - Shear Forces and Bending Moments, Bending and Shear Stresses, Elastic Deflection of Beams ; Torsion – Open and closed sections, Shear centre, warping cross-section properties, Shear flow in closed and open sections, Torsion of shafts, closed and open sections; Advanced Topics - Buckling of Compressed Members and Slenderness Ratio, Elements of Structural Vibrations, Fundamentals of Fatigue Analysis

ENGG(SERC) 1-908: Computational Methods Faculty: Dr. A. Rama Mohan Rao ,Shri. J. Rajasankar

(L-T-P-C) : 3-0-0-3

Introduction, finite floating point arithmetic, catastrophic cancellation, chopping and rounding errors; Solution of nonlinear equations; bisection method, secant method, Newton's method, fixed point iteration, Muller's method; Numerical optimization; Method of golden section search, Newton's method optimization; Solutions of linear algebraic equations; forwarding Gaussian elimination, pivoting, scaling, back substitution, LU-decomposition, norms and errors, condition numbers, iterations, Newton's method for systems, computer implementation; Interpolation; Lagrange interpolation, Newton interpolation, inverse interpolation; Numerical Integration; finite

differences, Newton cotes rules, trapezoidal rule, Simpson's rule, extrapolation, Gaussian quadrature; Numerical solution of ordinary differential equations; Euler's method, Runge-Kutta method, multi-step methods, predictorcorrector methods, rates of convergence, global errors, algebraic and shooting methods, for boundary value problems, computer implementation

ENGG(SERC) 1-909 :Advanced Engineering Mathematics Faculty:, Dr. N. Gopalakrishnan, Shri K. Venkataraman

(L-T-P-C) : 3-0-0-3

Ordinary Differential Equations of the First Order , Ordinary Linear Differential Equation, Laplace Transformation, Line and Surface Integrals. Integral Theorems, Matrices and Determinants (Systems of Linear Equations), Fourier Series and Integrals, Partial Differential Equations, Sequences and Series, Taylor and Laurent Series, Special Functions. Asymptotic Expansions

ENGG(SERC) 2-906: Dynamics of Structures Course Coordinator: Dr. K. Muthumani

(L-T-P-C) : 3-0-1-3

Introduction: dynamic vs. static response; types of dynamic loading: seismic, impact, wind, blast; Principles of dynamics - Formulation of equations of motion by different methods - single degree of freedom systems - free and forced response - effect of damping; Multi-degree of freedom systems -Formulation of equations of motion Eigen values problems - Modes shapes and orthonormality of modes -Approximate methods of extraction of eigen values and natural frequency; Seismic response spectra Response spectra parameters; response spectra relationships; Dynamic response of MDOF systems - Mode superposition techniques -Numerical integration procedures; Continuous systems - Modeling - free and forced vibration of bars and beams; MDOFs : Response spectra analysis; Response spectra analysis; SRSS and CQC combination methods; Introduction to frequency domain analysis; Time domain vs. frequency domain; Fourier series; the fast Fourier transform (FFT);assessing frequency content; frequency based filtering; Application of finite element method in structural dynamics

ENGG(SERC) 2-911: Bridge Engineering Course coordinator: Dr. K. Ramanjaneyulu

(L-T-P-C) : 3-0-1-3 (4-0-0) jasankar

Introduction - historical development, Classification and components of bridges, choice of type of the bridges, bridge aesthetics; Bridge codes – standard specifications for highway and railway bridges; Analysis and design of RC and PSC bridge decks, load distribution in slab and girder bridges, analysis and design of voided slab bridge decks, behaviour of skew bridge decks; Analysis and design of RC and PSC box-girder bridge decks; Analysis and design of steel and composite bridges; Design of bearings; Design of substructure and foundations - piers and abutments of different types, shallow and deep foundations; Modern methods of construction - Incremental launching and its impact on analysis and design, segmental construction ; Introduction to analysis and design of long span bridges: suspension and cable stayed bridges

ENGG(SERC) 2-912: Earthquake Engineering Faculty: Dr. P. Kamatchi; Shri G.V. Rama Rao

(L-T-P-C) : 3-0-1-3 (4-1-0) jasankar

Elements of Engineering Seismology - Causes of earthquakes - seismic waves – magnitude and intensity characteristics of strong earthquake ground motions - Seismic Susceptibility of Indian Subcontinent; Performance of structures under past earthquakes - Lessons learnt - Behaviour of RC, steel, Masonry and prestressed concrete structures under cyclic loading; Introduction to theory of vibrations -Flexibility of long and

short period structures - concept of response spectrum; Building forms for earthquake resistance - Building Systems – Rigid Frames, Braced Frames, Shear Walls - Structural Configuration; Seismic design philosophy Concept of Earthquake Resistant Design - Evaluation of earthquake load on structures based on IS: 1893 – response spectrum method - 3 D computer analysis of building – Importance of detailing IS 13920 Seismic Design of Non Engineered construction; Seismic evaluation and retrofitting of structures; Soil performance – Soil liquefaction – Soil structure interaction ; Seismic design provisions for bridges, dams, tanks and Industrial structures; Modern Concepts: Introduction to Passive and Active Control of Civil Engineering Structures, Base Isolation, energy dissipation devices, Adaptive systems – Case studies ENGG(SERC) 2-908: RCC & Prestressed Concrete Structures (L-T-P-C) : 3-0-1-3 Faculty: Dr. K. Ramanjaneyulu, Dr. B. H. Bharath Kumar , Dr. A. Rama Chandra Murthy

Yield line method of Design of Slabs: Equilibrium and virtual work methods of analysis, Rectangular slabs and triangular slabs with various edge conditions – yield line patterns, Circular slabs, Design for limit state of strength and serviceability, Orthotropically reinforced slabs; Design of Grid Floors: General features, Rigorous and approximate methods of analysis, Design of grid floors.; Design of Shear walls; Design of Deep Beams and Corbels; Design of Flat Slabs; Design of bunkers silos and chimneys; Analysis of stresses in concrete chimneys- uncracked and cracked sections- Codal provisions- Design of chimney; Importance of Detailing in Reinforced Concrete Construction. Introduction to prestressed concrete: materials, types of prestressing systems and devices; analysis of prestressed concrete elements for flexure: concepts of stresses at transfer and service loads, ultimate strength in flexure, losses in prestress, anchorage zone stresses; philosophy of design: limit state design for flexure and shear, tendon profiles in post-tensioned and pre-tensioned members, comparative analysis of provisions of international standards; statically indeterminate structures: continuous beams and portals, secondary moments, concordancy of tendon profiles ; composite construction: longitudinal shear transfer, transverse shear, stage prestressing, creep and shrinkage effects; external prestressing; design of prestressed concrete pipes, tanks, slabs, and cylindrical shells.;construction aspects – prestressing, precast-prestressed concrete, stressing sequence; safe demolition of psc structures; methods for safe distressing of prestressed concrete structures

ENGG(SERC) 2-909: Finite Element Technology-I Faculty: Dr. Nagesh R Iyer , Dr. A. Rama Mohan Rao , Shri J. Rajasankar

(L-T-P-C) : 3-0-0-3 (4-2-0) jasankar

Review of matrix methods of structural analysis ; Stationary Principles, Rayleigh-Ritz method and Interpolation : Principle of stationary potential energy, Rayleigh-Ritz method, Stationary principles and governing equations, Finite element form Rayleigh-Ritz method, FEM formulation from a functional, Interpolation, C0 and C1 elements; Displacement based Element formulations:Overview of element stiffness matrix, Load formulations, Equilibrium and compatibility, convergence requirements , patch test, stress calculations, plane stress, plane strain, axisymmetric and solid finite elements, triangular, quadrilateral, tetrahedron and hexahedron elements.Isoparametric finite elements :1-D, 2-D and 3-D shape functions, Lagrangian and Serendipity family of elements, numerical integration, validity of isoparametric elements, element and mesh instabilities, coordinate transformations, handling of constraints; Plate bending elements :Plate bending theory, Mindlin and Kirchhoff element formulations, Concepts of locking, Full, reduced integration and selective reduced techniques, ENGG(SERC) 3-910: Uncertainty Handling in Engineering Decision Making Coordinator: Dr. K. Balaji Rao

(L-T-P-C) : 3-0-1-3

Introduction: Basic Definitions; Examples; Different types of uncertainties; Exposure to formal frameworks for handling uncertainties; Theory & Application of Probability and Statistics: Nature and Purpose of Mathematical

Statistics; Tabular and Graphical Representation of Samples; Sample Mean and Sample Variance; Random Experiments, Outcomes, Events; Probability; Permutations and Combinations; Random Variables. Discrete and Continuous Distributions; Mean and Variance of a Distribution; Binomial, Poisson, and Hypergeometric Distributions; Normal Distribution; Distributions of Several Random Variables; Random Sampling. Random Numbers; Estimation of Parameters; Confidence Intervals; Testing of Hypotheses, Decisions; Quality Control; Acceptance Sampling; Goodness of Fit. x2-Test; Nonparametric Tests; Pairs of Measurements. Statistical Tables; Application of stochastic processes for engineering decision making : Basic definition of stochastic process; Some commonly used stochastic processes; Learning models for engineering decision making – learning in both stationary and non-stationary environment; Application of fuzzy sets in engineering decision making :Basic definition of fuzzy sets; Some commonly used fuzzy sets; Use of fuzzy stochastic models for engineering decision making; Handling of uncertainties using possibility and plausibility theories ; Introduction to application of game-theoretic approaches for engineering designs

ENGG(SERC) 3-909: Soft Computing Coordinator: Dr. A. Rama Mohan Rao

(L-T-P-C) : 4-0-1-4

Introduction: Introduction of Soft-computing tools, Fuzzy Logic, concepts meta-heuristics, Evolutionary algorithms, Neural Networks and Probabilistic Reasoning; Artificial Neural Networks (ANN): Different Architectures, Back-propagation Algorithm, Hybrid Learning Rule, Supervised Learning- Perceptrons, Adaline, Back-propagation Multilayer Perceptrons, Radial Basis function Networks. Unsupervised Learning – Competitive Learning Network, Kohonen Self-Organizing Networks, Hebbian Learning, The Hopfield Network; Support Vector Machines: Support vector machines and other kernel based learning algorithms, Implementation techniques for SVM, application of SVM for engineering problems; Fuzzy Set Theory: Basic Definition and terminology, Basic Concepts of Fuzzy Logic, Set Theoretic Operators, Membership functions- formulation and parameterization. Fuzzy Union, Intersection, and Complement. Fuzzy Rules and Fuzzy Reasoning. Fuzzy Inference Systems- Mamdani and Sugeno Fuzzy models. Fuzzy Associative Memories;Evolutionary Algorithms: Basics of evolutionary Algorithms, Design issues in evolutionary Algorithm, evolutionary computing; Applications with Soft Computing Tools: Case studies with ANN, fuzzy and Hybrid approaches

ENGG(SERC) 2-910:Plate and Shell Structures Faculty: Dr. K. Balji Rao; Dr. K. Ramanjaneyulu

(L-T-P-C) : 3-0-1-3

Thin plates, Kirchhoff theory - strain displacement relations, stresses and stress resultants, constitutive equations, equilibrium equations, boundary conditions, Analysis of rectangular and circular plates with different boundary conditions and loadings ; thick plates-Reissner-Mindlin-Naghadi type theories; orthotropic plates, plates on elastic foundation; Buckling of plates; Membrane and bending theory for analysis of singly curved and doubly curved shells – long and short cylindrical shells, single and multi barrel shells, Beam-arch approximation for long cylindrical shells; Analysis of surfaces of revolution – domes, cylindrical, conical and hyperboloid of revolution subjected to different types of loadings; Analysis and shells of translation - elliptic paraboloids, hyperbolic paraboloids; Analysis of folded plates;

ENGG(SERC) 3-907: Metal Structure Behaviour and Design

(L-T-P-C) : 3-0-1-3

Faculty: Dr. S.J. Mohan, Dr. G.S. Palani , Dr. N. Prasada Rao Frame design review -Second Order Effects and Moment Magnification; Stability and Leaning Columns; Philosophies of design - ASD vs. LRFD and Structural Reliability; Failure Criteria; Brittle Fracture/Ductile Yielding; Von Mises Yield Criteria; Fatigue - Stress Life, Strain Life, Fracture Mechanics; Variable Amplitude Loading and Miner’s Rule; Fatigue Design Requirements; Bending behavior - General Flexural Theory; Unsymmetrical Bending Biaxial Bending Tapered Members; Torsion - Pure Torsion Shear Flow Shear; Center

of Open Thin-Walled Sections Uniform Torsion; Torsion of Structural Shapes; Non-uniform Torsion; Combined Torsion and Bending Torsion of Closed Thin-Walled Sections, Single Cell and Multi-Cell; Lateral torsional buckling - Elastic and Inelastic; Columns, plates, and compression members - Local Buckling of Plate Elements; Design Criteria; Torsional Compression Buckling; Design of Aluminum Structures: Introduction, Stress-Strain Relationship, Permissible Stresses, Tension and Compression Members, Laced and Battened nd

Columns, Beams; Beam-column and frame behavior –Approximate 2 order effects; Elastic and Inelastic Behavior; CONNECTIONS - Review of Bolt and Weld Strength; Riveted and Bolted Connections Design Aids Example; Microwave Towers – Introduction, structural configuration, function, analysis and design. Transmission Towers – Introduction, structural configuration, bracing systems, analysis and design, codal provision for design of tower and foundation; Tubular Structures - Tubular Trusses, joint details, tubular scaffoldings, codal provisions; Cold Form light gauge section- Type of cross section, Stiffened, multiple stiffened and un-stiffened element, flat- width ratio, effective design width, Design of light gauge compression, tension and flexural members

ENGG(SERC) 3-906: Health Monitoring of Structures -1

(L-T-P-C) : 3-0-1-3

Faculty: Dr. K. Ravisankar, Dr. N. Gopalakrishnan Static Field Testing: Requirements for carrying out static field testing -Types of static tests - Behavioural/ Diagnostic tests - Proof tests - Simulation and loading methods - Static response measurement; Dynamic Field Testing: Stress history data - Dynamic load allowance tests - Ambient vibration tests - Forced Vibration Method Dynamic response methods; Periodic and Continuous Monitoring; Long term performance monitoring using integrated sensing methods - Monitoring through ambient vibration - Monitoring through testing under service load conditions - Assessment of crack growth - Loss of prestress; Data Acquisition Systems; Static data acquisition systems - Dynamic data acquisition systems - Hardware for Remote data acquisition systems; Remote Structural Health Monitoring: Importance and Advantages - Methodology - RF/PSTN/GSM/Satellite Communications - Networking of sensors - Data compression technique; Case Studies

ENGG(SERC) 2-913: Repair & Rehabilitation of Concrete Structures Faculty: Dr. B.H. Bharthkumar, Shri T.S. Krishnamurthy

(L-T-P-C) : 3-0-1-3

General: Introduction , cause of deterioration of concrete structures, Diagnostic methods & analysis, preliminary investigations ,experimental investigations using NDT, load testing, corrosion mapping, core drilling method; Serviceability and Durability: Effects due to climate, temperature, chemicals, wear and erosion, Design and construction errors; Maintenance and Repair Strategies: Definitions: Maintenance, repair and rehabilitation, Facets of Maintenance importance of Maintenance Preventive measures on various aspects. Assessment procedure for evaluating a damaged structure; Causes of deterioration – testing techniques; Techniques for Repair: Corrosion protection, corrosion inhibitors, corrosion resistant steels, coatings, cathodic protection. Strengthening of structural elements with various methods; Case Studies: Structures affected due to corrosion related failure

ENGG(SERC) 3-908: New Composite Materials in Civil Engineering Applications (L-T-P-C) : 3-0-1-3 Faculty: Shri T.S. Krishnamurthy, Dr. (Mrs) J. Annie Peter

Concrete Composite: Fresh concrete and hardened concrete – Mix Design – Use of Admixtures Mechanical and Durablity properties; Fibre Reinforced Concrete (FRC):Types of Fibres – Factors affecting strength and stiffness of fibre concrete– Production of FRC – Tests on FRC – Applications of FRC; ferrocement-production and application; High Performance Concrete (HPC): Definition – Constituent materials – Production methods – Advantages of HPC – Applications of HPC; self compacting concrete; definition – constituent material – mix proportion – production methods – various tests on SCC – applications of SCC; Polymer Concrete Composite:

Classification of Polymer concrete – Methods of Production – Advantages of Polymer Concrete – Applications of Polymer Concrete; FRP composites: Constituent materials – Method of Productions – Properties and Production method – Applications

ENGG(SERC) 2-907: Engineering for Natural Hazards Faculty: Dr. S. Arunachalam, Dr. S. Selvirajan, Dr. K. Balaji Rao

(L-T-P-C) : 3-0-1-3

Hazard Characteristics: Seismology and ground motion characteristics; Extreme wind Characteristics; Hazard Estimation: Deterministic methods; Stochastic methods; Probabilistic and deterministic seismic hazard analysis; Risk analysis of cyclonic wind speed; Post Disaster Damage Surveys: Earthquake Disaster; Cyclone Disaster; Materials and Methodology of Constructions; Vulnerability Analysis: Damage Probability Matrix approach; Fragility Analysis approach; Risk analysis life quality index Approach; Guidelines for Disaster Resistant Structures: Earthquake Disaster; Cyclone Disaster

ENGG(SERC) 2-909: Finite Element Technology-II (L-T-P-C) : 3-0-1-3 Faculty: Dr. Nagesh R Iyer, Dr. A. Rama Mohan Rao, Shri J. Rajasankar, Dr. G.S. Palani Introduction to nonlinear FEA – Concept of geometric and material nonlinearity, Total and updated Lagrangian formulation, Constitutive relations, Solution techniques; Formulations related to nonlinear dynamic analysis Error estimation and adaptive refinement techniques – A posteriori error estimation for static, vibration and dynamic problems; h-, p-, r- and mixed adaptive refinements. Introduction to mesh free methods

ENGG(SERC) 3-912: Fatigue & Fracture of Engineering Structures (L-T-P-C) : 3-0-1-3 Faculty: Dr. G. Raghava, Dr. G.S. Palani, Shri P. Gandhi, Shri T.S. Krishnamurthy

Introduction to Fatigue: Loads – Cyclic loads – High cycle fatigue – Low cycle fatigue; Stress-life Approach: S-N curve – Size effect – Loading effect – Surface … plating, thermal, and mechanical – Temperature – Environment; Strain-life Approach: Introduction – Material behaviour – Monotonic stress-strain behaviour, Basic definition – True and engineering stress-strain relationship, Cyclic stress-strain behaviour, Cyclic strain hardening and softening, Cyclic stress-strain curve determination, Stress-strain power law relation; Fatigue Life Calculation: – Prediction of fatigue life using S-N and Miner’s approach – General,calculation of equivalent stress range, stresses to be considered, S-N curves and joint classifications, – Prediction of crack propagation using da/dN vs ΔK curves – General, Constant amplitude loading, variable amplitude loading, geometric functions and crack growth integrals– General, load calculation, stress calculation, … probability of failure – Design formats – General, allowable stresses, allowable cumulative damage ratio, comments on the design formats; Fracture:…Stress distribution at discontinuities – Stress concentration factors – Cracks … Linear Elastic Fracture Mechanics (LEFM):Stress intensity factor – monotonic and cyclic loads - Fracture toughness – Energy theories – J-integral; Crack Growth Studies: Fatigue crack growth … Constant amplitude loading – Variable amplitude loading – Crack growth models –Remaining life prediction – Residual strength evaluation – Plastic collapse condition, Yield condition, Remaining life approach … Fracture of Concrete Structures: Fracture mechanics approach for concrete – Limitations – Nonlinear fracture models with tension softening – Fracture energy – size effect – Remaining life prediction – Residual strength evaluation. ENGG(SERC) 2-915: Engineering Materials Faculty: Shri T.S. Krishnamurthy, Dr. BH Bharat Kumar

Concretes: high strength and high performance concrete-fiber reinforced concrete

(L-T-P-C) : 3-0-1-3

Metals: new alloy steels-aluminum and its products-other alloys Composites: plastics-reinforced polymers-frp-cellular cores Other materials: water proofing compounds-non -weathering materials-flooring and facade materials. Smart and intelligent materials: brief outline and uses ENGG(SERC) 3-914: Advanced Engineering Materials Faculty: Shri T.S. Krishnamurthy, Dr. B.H. Bharath Kumar

(L-T-P-C) : 3-0-1-3

Concretes: High strength and high performance concrete – fibre reinforced concrete Metals New alloy steels – aluminium and its products – other alloy Composites Plastics –reinforced polymers – frp – cellular cores Other materials Water proofing compounds – non-weathering materials – flooring and facade materials Smart and intelligent materials ENGG(SERC) 3-915: Probability and statistics Coordinator: Dr. K Balaji Rao

(L-T-P-C) : 3-0-0-3

Probability: Sample space and events – Probability – The axioms of probability – SomeElementary theorems Conditional probability – Baye’s theorem. Random variables – Discrete and continuous – Distribution – Distribution function. Distribution Binomial and poison distributions Normal distribution – related properties.Sampling distribution: Populations and samples - Sampling distributions of mean (known and unknown) proportions, sums and differences. Estimation: Point estimation–interval estimation-Bayesian estimation.Test of Hypothesis – Means– Hypothesis concerning one and two means– Type I and Type II errors. One tail, two-tail tests. Tests of significance – Student’s t-test, F-test,\c test. Estimation of proportions. Queuing Theory: Pure Birth and Death Process M/M/1 Model and Simple Problems.

ENGG(SERC) 3-910: Uncertainty Handling in Engineering Decision Making Faculty: Dr. K. Balaji Rao, Dr. M.B. Anoop

(L-T-P-C) : 4-0-1-4

Introduction: Basic Definitions; Examples., Different types of uncertainties., Exposure to formal frameworks for handling uncertainties. Application of Probability and Statistics in engineering decision making:Basic definitions of probability; random variables., Setting-up of framework for engineering decision making in the probabilistic/random environment., Statistical analysis of engineering data., Statistical decision making. Application of stochastic processes for engineering decision making:Basic definition of stochastic process., Some commonly used stochastic processes., Learning models for engineering decision making – learning in both stationary and non-stationary environment. Application of fuzzy sets in engineering decision making: Basic definition of fuzzy sets., Some commonly used fuzzy sets., Use of fuzzy stochastic models for engineering decision making. Handling of uncertainties using possibility and plausibility theories. Introduction to application of game-theoretic approaches for engineering designs

ENGG(SERC) 3-908: New Composite Materials in Civil Engineering Applications (L-T-P-C) : 3-0-1-3 Faculty: Shri T.S. Krishnamurthy, Dr. (Mrs) J. Annie Peter

Concrete Composite: Fresh concrete and hardened concrete – Mix Design – Use of Admixtures Mechanical and Durablity properties; Fibre Reinforced Concrete (FRC):Types of Fibres – Factors affecting strength and stiffness of fibre concrete– Production of FRC – Tests on FRC – Applications of FRC; ferrocement-production and application; High Performance Concrete (HPC): Definition – Constituent materials – Production methods – Advantages of HPC – Applications of HPC; self compacting concrete; definition – constituent material – mix proportion – production methods – various tests on scc – applications of scc; Polymer Concrete Composite: Classification of Polymer concrete – Methods of Production – Advantages of Polymer Concrete – Applications of Polymer Concrete; FRP composites: Constituent materials – Method of Productions – Properties and Production method – Applications ENGG(SERC) 3-916: Structural Control Faculty: Dr. A. Rama Mohan Rao; Dr. N. Gopalakrishnan

(L-T-P-C) : 3-0-1-3

Introduction: Review of fundamentals of single degree freedom systems-two degree freedom systems, multi degree freedom systems, continuous systems, determination of natural frequencies and mode shapes, numerical methods in vibration analysis Passivevibration control: Introduction-reduction of vibration at the source-control of vibration-by structural design-material selection-localized additions-artificial damping-resilient isolation, vibration isolation, vibration absorbers, application of smart material in passive vibration control Active vibration control: Introductions-concepts and applications, elements of linear control systems, the state equation, solution of the state equation, stability, controllability and observability Control mechanisms: Active tendon control, active mass damper and active mass driver, pulse generator, aerodynamic appendages, other control mechanisms Control algorithms: Control algorithms: introduction to control algorithms, classical linear optimal control, pole assignment, instantaneous optimal control, independent modal space control (imsc), bounded state control, other control algorithms Practical issues on active control implementation: Paractical considerations, modelling errors, time dealy, structal nonlinearities, uncertainities in structural paramenters, limited number of sensors & controllers, discrete time control, reliability Structural control using smart materials: Smart materials for structural control-types and characteristic review of smart structures - active vibration control in smart structures, finite element modelling of piezoelectric materials,

ENGG(SERC) 2-917: Stability of Structures Faculty: Dr. N. Gopalakrishnan, Dr. A. Rama Mohan Rao

(L-T-P-C) : 3-0-1-3

Stability of columns:Concepts of elastic structural stability- analytical approaches to stability - characteristics of stability analysis- elastic buckling of columns- equilibrium; energy and imperfection approaches – non-prismatic columns- built up colyumns- orthogonality of buckling modes- effect of shear on buckling load - large deflection theory. Methods of analysis and in elastic buckling : Approximate methods – rayleigh and galerkin methods – numerical methods – finite difference and finite element - analysis of columns – experimental study of column behaviour – south well plot - column curves - derivation of column design formula - effective length of columns - inelastic behaviour- tangent modulus and double modulus theory

Beam columns and frames: Beam column behaviour- standard cases- continuous columns and beam columns – column on elastic foundation – buckling of frames – single storey portal frames with and without side sway – classical and stiffness methods – approximate evaluation of critical loads in multistoried frames – use of wood’s charts. Buckling of beams: Lateral buckling of beams – energy method- application to symmetric and simply symmetric i beams – simply supported and cantilever beams - narrow rectangular cross sections- – numerical solutions – torsional buckling – uniform and non uniform torsion on open cross section - flexural torsional buckling – equilibrium and energy approach. Buckling of thin plates : Isotropic rectangular plates - governing differential equations - simply supported on all edges – use of energy methods – plates with stiffeners – numerical techniques. ENGG(SERC3) 3-917: Health monitoring of structures – II Faculty: Dr. K. Ravisankar, Dr. N. Gopalkrishnan

(L-T-P-C) : 4-0-1-4

Methods of health assessment of strucutres Static field testing: Requirements for carrying out static field testing - types of static tests - behavioural/ diagnostic tests – proof Tests - simulation and loading methods - static response measurement Dynamic field testing: Stress history data - dynamic load allowance tests - ambient vibration tests - forced vibration method - Dynamic response methods Periodic and continuous monitoring: Long term performance monitoring using integrated sensing methods monitoring through ambient vibration - Monitoring through testing under service load conditions - assessment of crack growth - loss of prestress Data acquisition systems: Static data acquisition systems - dynamic data acquisition systems - hardware for remote data acquisition Systems Damage diagnostic techniques: Frequency domain methods, time domain methods, methods based on time frequency analysis, methods based on time series analysis, statistical based methods, methods based on AI etc., Remote structural health monitoring: Importance and advantages - methodology - rf/pstn/gsm/satellite communications - networking of sensors data compression technique Case studies

ENGG(SERC) 3-918: Soil structure interaction Faculty: Dr. Nagesh R Iyer, Shri J. Rajasankar

(L-T-P-C) : 3-0-1-3

Soil-foundation interaction: Introduction to soil-foundation interaction problems,soil behaviour,foundation behjaviour,interface behaviour,scope of soil foundation interaction analysis,soil response models,winkler,elastic continuum,two parameter elastic models,elastic plastic behaviour,time dependent behaviour Beam on elastic foundation- soil models: Infinite beam,two parameters,isotropic elastic half space,analysis of beams of finite length,classification of finite beams in relation to their stiffness Plate on elastic medium: Infinite plate,winkler,two parameters,isotropic elastic medium,thin and thick plates,analysis of finite plates,rectangular and circular plates,numerical analysis of finite plates,simple solutions Elastic analysis of pile: Elastic analysis of single pile,theoretical solutions for settlement and load distributions,analysis of pile group,interaction analysis,load distribution in groups with rigid cap.

Laterally loaded pile: Load deflection prediction for laterally loaded piles,subgrade reaction and elastic analysis,interaction analysis,pile raft system, solutions through influence charts ENGG(SERC) 3-919: Advanced concrete technology Faculty:

(L-T-P-C) : 3-0-1-3

Cement: Composition of opc-manufacture-modified portland cements-hydration process of portland cementsstructure of hydrated cement pastes Admixtures: Composition of opc-manufacture-modified portland cements-hydration process of portland cements-structure of hydrated cement pastes Aggregates: Mineral admixtures-slags-pozolanas and fillers-chemical admixtures-solutes retarders-air entraining agents- water proofing compounds-plasticizers and super plasticizers Fresh concrete: Shape and mechanical properties-absorption and physical durability-chemical stability and packing characteristics Properties of concrete: Workability-mix proportioning-mixes incorporating fly -ash -mixes for high performance concrete Interfacial transition zone-fracture strength-mechanical properties-high strength concrete-shrinkagecreep- other properties Durability of concrete: Basic consideration-Stability of constituents-Chemical Attack-Corrosion of Reinforcing steel Special topics: Manipulation of strength of concrete-Fiber reinforced concrete-Quality control ENGG(SERC) 2-918: Structural Design for Dynamic Loads Coordinator: Dr. K. Muthumani

(L-T-P-C) : 3-0-1-3

Introduction: Factors affecting design against dynamic loads - behaviour of concrete, steel, masonry and soil under impact and cyclic loads - recap of structural dynamics with reference to sdof, mdof and continuum systems - ductility and its importance. Design against earthquakes:Earthquake characterisation - response spectra - seismic coeffcient and response spectra methods of estimating loads - response of framed, braced frames and shear wall buildings - design as per bis codes of practice - ductility based design. Design against blast and impact: Characteristics of internal and external blast - impact and impulse loads pressure distribution on buildings above ground due to external blast - underground explosion - design of bulidings for blast and impact as per bis codes of practice. Design against wind: Characteristics of wind - basic and design wind speeds - effect of premeability of the structure – pressure coefficient - aeroelastic and aerodynamic effects - design as per bis code of practice including gust factor approach - tall buildings, stacks and chimneys. Special considerations: Energy absorption capacity – ductility of the material and the structure – detailing for ductility – passive and active control of vibrations – new and favourable materials. ENGG(SERC) 1-920 : Research Methodology & Professional Practice Coordinator: Dr. Nagesh R Iyer

(L-T-P-C) : 2-0-0-2

Research Methodology : Literature review ; Searching the literature; Managing references; Effective scientific writing; Effective scientific presentation; Intellectual property management ; Writing and reading Patents ; Research planning; Ethics in Science Introduction to organisational structure; Communication Skills; Engineering Ethics and Social Responsibility; Introduction to Decision Making; Professionalism Using Standard; Social Intelligence; Decision Making in Company; Professional Judgment; Entrepreneurship and Risk Management; inter-relationships between professionalism and ethics; inter-relationships between Ethics and Social Intelligence; inter-relationships between Professional Judgment and Social Intelligence; mentoring; leadership exercises; group dynamics; conflict resolution NGG(SERC) 3-921 : Advanced Self-study on Special Topic-A Coordinator: Selected Scientists or Guide

(L-T-P-C) : 1-1-6-4

This will involve readings from published literature or books about new frontiers on a specific topic related specifically to the research topic or related areas. A report needs to be submitted and an open seminar on the special topic needs to be presented. ENGG(SERC) 3-922 : Advanced course on Special Topic-B

(L-T-PC) : 3-1-4-4

Coordinator: Selected Scientists or Guide

This will involve one to one teaching by thesis supervisor or any expert faculty member in the very specific topic of candidates research

ENGG(SERC) 1-928 : Research Proposal Writing

(L-T-PC) : 1-1-4-4

Coordinator: Selected Scientists

Technical Communications: Role and importance of technical communication; Effective written and oral communication; Technical report writing; Technical/R&D proposals; Research paper writing; Letter writing and Official correspondence; Emails; Oral communication in meetings and group discussions; Oral Presentations; Use of modern aids. Definition of a scientific project proposal; Components of a proposal; Need and purpose of the proposal; Aims and objectives; Background and present status; Proposed methodologies and approaches; Scheduling and mile-stones; Resource allocation; Budgeting; Monitoring and evaluation mechanisms; Referencing and citing; Use of data, graphs, tables, figures; Proposal funding agencies and their formats. Every student needs to submit two proposals --- one related to PhD research topic and the second in any field of structural Engineering

ENGG(SERC) 1-929 : CSIR-800 Societal Programme Coordinator: Selected Scientists

(L-T-PC) : 0-0-8-4

A project needs to be undertaken in rural area for 6-8 weeks duration aligned to the CSIR-800 programme. The theme of the project may be chosen from the CSIR-800 document or from any other government department related to benefiting and empowering the economically lower 800 million Indians by way of S&T innovations. The aim is to interact with underprivileged people in the villages and propose solutions in the area of health, agriculture, energy, water, food, education, housing and physical infrastructure etc.

Annexure III-D

Course Content of Mathematical & Information Sciences

Special Meeting of Senate 08.06.2012

Final Draft

Academy of Scientific and Innovative Research: Mathematical and Information Sciences (AcSIR:MIS) Ph D Programme: 2012 Contents 1. Scope of Ph D Programme in MIS 2. Selection Procedure 3. Credit Requirements 4. Summary of Ph D Courses in MIS (Course Titles and LTPC), with list of faculty (a) C-MMACS (b) NAL (c) NISCAIR (d) NISTADS (e) URDIP 5. Outline of Ph D Courses in MIS (Content, Faculty, Suggested Reading) (a) C-MMACS (b) NAL (c) NISCAIR (d) NISTADS (e) URDIP 6. List of Faculty 7. Broad Scope of CSIR-800 Course

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Summary of Ph D Courses C-MMACS

Course No. MIS01 MIS02

Title

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MIS-207 MIS-206

Quantitative Science and Reasoning Principles and Techniques of Mathematical Modelling Applied Computational Methods Scientific Computing and Networking Mathematics Modeling: Principles and Application CSIR-800 Societal Program (MIS or Interdisciplinary) Subject Proposal (2 proposals in MIS area) Electives Introduction to Non-linear Dynamics Advanced Information Security Scientific and Parallel Computing Cyber and Network Security Advanced Self Study on Special topic Research Methodology, Technical Writing & Communication Skills Finite Element Method Numerical Weather Prediction

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0 0

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3 3

MIS-208

Statistical Physics and its Practical Applications

3

0

0

3

MIS03 MIS04 MIS05 MIS06 MIS07 MIS610 MIS611 MIS612 MIS613 MIS702 MIS501*@

Principal Faculty 1. 2. 3. 4. 5. 6. 7. 8. 9.

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Prof. V K Gaur (Alumni) Dr R N Singh (Alumni) Prof. P Seshu Prof. T R Rammohan Prof. P Goswami Dr G K Patra, C-MMACS Dr I A Parvez Dr K V Ramesh Dr V Rakesh

NAL Course No. MIS601 MIS602 MIS603 MIS604 MIS605 MIS606 MIS607 MIS609 MIS701 MIS702

Title

Principal Faculty (Partial List) 1. Prof. R M Jha 2. Prof. V Mudkavi

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Electives

Fundamentals of Electronic Materials & Semiconductor Devices Physics & Technology of Thin Films Advanced Materials Characterization Techniques Nanostructured materials Superconductivity & Magnetic Materials Advanced Measurement Techniques & Metrology Advanced Computational Physics Engineering Materials Quantum Optics & Advanced Solid State Optical Devices Advanced Self Study on Special topic

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NISCAIR (A) Computational Biology & Bioinformatics (CBB) 1. Common Core (14 Credits) S.No. Course No.

Course Title

L-T-P-C

01.

CBB (NISCAIR)-101

Research Methodology

1-1-0-2

02.

CBB (NISCAIR)-301

Advanced Self Study

0-2-4-4

03.

CBB (NISCAIR)-401

Project Proposal writing

0-1-6-4

04.

CBB (NISCAIR)-402

CSIR-800 Societal program

0-0-8-4

2. Programme Electives (6 Credits) S.No. Course No.

Course Title

L-T-P-C

01.

CBB (NISCAIR)-201

Basic & Advance Bioinformatics

2-1-0-3

02.

CBB (NISCAIR)-202

Languages Learning in Bioinformatics

2-1-0-3

03.

CBB (NISCAIR)-203

Database Management Systems

2-1-0-3

04.

CBB (NISCAIR)-204

Discovery & Translational Bioinformatics

2-1-0-3

05.

CBB (NISCAIR)-205

2-1-0-3

06.

CBB (NISCAIR)-206

07.

CBB (NISCAIR)-207

Genomics, Metagenomics, Proteomics & Transcriptomics Computational Biology Approaches for Drug Discovery Computational Immunology / Immunoinformatics

2-1-0-3

08.

CBB (NISCAIR)-208

Computational Neurology/Neuroinformatics

2-1-0-3

Principal Faculty 1. Dr. Tarakanta Jana 2. Shri Hasan Javed khan 3. Dr. S. C. Sharma 4. Dr. G. Mahesh 5. Shri S.R. Kundu 6. Shri Mukesh Pund 7. Mrs. Charu Verma 8. Shri Sanjay Burde 9. Shri C.B. Singh 10. Dr. Vijayalakshmi

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2-1-0-3

(B) Database systems & Climate Change Informatics (DBS & CCI) COMMON CORE (14 CREDIT) Title of the course S.No. Course No.

L T P C

1. DBS (NISCAIR)101

Research Methodology

1

1

0 2

2. DBS (NISCAIR)301

Advance Self Studies

0

2

4 4

3. DBS (NISCAIR)401

Project proposal Writing

0

1

6 4

4. DBS (NISCAIR)802

CSIR-800 Societal Program

0

0

8 4

Programme Electives (6 Credits) S.No. Course No. Title of the course

L T P C

1. DBS (NISCAIR)201

Data Base Management System

2

1

0 3

2. DBS (NISCAIR)202

Environment and Environmental Impact Analyses

2

1

0 3

3. DBS (NISCAIR)203

Glaciology

2

1

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4. DBS (NISCAIR)204

Climatology

2

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5. DBS (NISCAIR)205

Ecology, Remote sensing and GIS

2

1

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6. DBS (NISCAIR)206

Introductory oceanography

2

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7. DBS (NISCAIR)207

Environmental ocean technology

2

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8. DBS (NISCAIR)208

Ocean resources

2

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9. DBS (NISCAIR)209

Integrated coastal zone management

2

1

0 3

10. DBS (NISCAIR)210

Oceans and climate change

2

1

0 3

Principal Faculties: January, 2012 1. Dr. P D Tyagi, 2. Dr. S C Sharma, 3. Dr. Majumdar, 4. Dr. Sanjay Sen Gupta, 5. Dr. Tarakanta Jana 6. Dr. G. Mahesh) 7. Dr. Rajeev Gupta, 8. Dr. R S Beniwal 9. Mrs. Charu Verma 10. Dr. Pankaj Gupta 11. Dr. Rajendran 12. Dr J Sundaresan Other than the above faculties the course will be supported by scientists from various CSIR, ISRO Institutes and faculties from IIT and universities who are associated with the collaborative projects developed by NISCAIR Final Draft

NISTADS

Course No.

Title

L T

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C

Core MIS(NISTADS)-1

Quantitative Research Methodology

1

1

1

1

MIS(NISTADS)-2

Introduction to Qualitative Research

1

1

1

1

MIS(NISTADS)-3

Indian Economy and Policy

2

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0

3

MIS(NISTADS)-4

Innovation systems and development

2

1

0

3

MIS(NISTADS)-5

Introduction to History of Science

1

2

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3

MIS(NISTADS)-6

Science & Technology Policy

2

1

0

3

MIS(NISTADS)-7

Science and Technology Systems - India and the World

1

2

0

3

Elective MIS(NISTADS)-1

Trade and Technology

1

1

0

2

MIS(NISTADS)-2

Enterprise Development through Value Chains Analysis

2

0

2

4

2

1

0

3

MIS(NISTADS)-3

Intellectual Property Rights in the Context of Research, Innovation and Development

MIS(NISTADS)-4

Environmental History

1

2

0

3

MIS(NISTADS)-5

Resource Planning & Policy

1

1

1

3

Principal Faculty (Partial List) 1. Dr. Yogesh Suman 2. Dr. Pradip Kumar Biswas 3. Dr. Sanjib Pohit 4. Dr. Rajeswari S. Raina 5. Dr. Satpal Sangwan 6. Dr. Sujit Bhattacharya 7. Dr.Tabassum Jamal 8. Dr. Subhan Khan 9. Dr. M. Rais 10. Dr. Tabassum Jamal 11. Dr. Kasturi Mandal

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URDIP S. No.

Course No.

Course Title

L-T-P-C1

1

MIS(URDIP)-381

IP Management

2-1-0-4

2

MIS(URDIP)-382

R&D Management

2-1-0-4

3

MIS( URDIP)-383

Technology Management

2-1-0-4

4

MIS(URDIP)-384

Patinformatics

1-0-2-2

5

MIS(URDIP)-385

Cheminformatics

2-0-2-3

6

MIS(URDIP)-386

Bioinformatics

2-0-2-3

1

Lecture-Tutorial-Practice-Credits

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Outline of Courses

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CSIR Centre for Mathematical Modelling and Computer Simulation (CSIR CMMACS) Institutional Profile: CSIR C-MMACS is a premier research institute established in 1988 with expertise in mathematical modelling and computer simulation in diverse Scientific and Engineering fields. It has a strong base of High Performance Computing (HPC) and has made significant contributions in the areas of Solid Earth, Ocean and Atmosphere Modelling, Network and Cyber security, Nonlinear Dynamical System and Computational Mechanics. CSIR C-MMACS has significant supercomputing and communication infrastructure with the new supercomputing facility connected to the National Knowledge Network (NKN) with a 1 Gbps Optical Fiber Link. Several CSIR laboratories have been remotely accessing the compute facility to solve challenging computational problems across various scientific disciplines. Research in the fields of cyber security and cryptography is actively pursued. Research focus in the field of Solid Earth Modelling is to estimate the seismic hazard and vulnerability of the Indian subcontinent through modelling and simulation of present day deformation and ground motion. Major achievements in this field are precise quantification and modelling of inter, co- and post-seismic surface deformation in Indian subcontinent. In addition to this we have given the deterministic hazard map of Indian subcontinent and seismic hazard map using Bayesian approach. Several models, algorithms and methodologies have been developed to address issues of high scientific significance and national importance in the areas of sustainability, climate change impact etc. A novel indigenous, ground based cloud seeding dispenser has been developed. In the field of Carbon cycle modelling, for the first time in India, carbon flux has been estimated by inverting the data from CO2 measurement stations at Hanle and Pondicherry which has reduced the posteriori uncertainties of these estimates significantly. We have integrated complex marine ecosystem and carbon chemistry models into an ocean general circulation model to simulate the oceanic carbon cycle over several time and space scales. Research on complex fluids carried out at C-MMACS has led to deep insight into chaotic behaviour at micro as well as macro-scales. Work on Lattice-Boltzmann method, which is eminently suited to parallel computation in fluid dynamics, has been initiated. Research work has also been initiated in the field of multi-scale modelling through modelling of interaction of aerosols and clouds into general circulation models. Sophisticated mathematical modelling aided by powerful computing and visualization has the potential to provide the cutting-edge to industry in a number of areas. CSIR C-MMACS combines high quality scientific output (SCI publications), academic programmes (Ph.D. students) and outreach in its approach. For details, visit www.cmmacs.ernet.in.

Final Draft

MIS01: Reasoning and Quantitative Thinking Principal Faculty: Prof V K Gaur Participating Faculty: R N Singh, G Prathap, P Goswami 1. Reasoning1-Philosophy2-Science3 : the eternal cycle towards framing significant questions and validating knowledge through examples4 2. Analysis of valid and invalid reasoning through examples such as syllogism5 Enquiry in the method(?) of establishing knowledge(science) through analysis of Aristotle’s Inductivedeductive schema and its continual refinement through the ages to Popper’s falsification criteria. 3. An understanding of the validity and value of Induction through analysis of Mathematical Induction and exploration of ‘inductive processes’ discernible in the road to some key scientific discoveries 4. An exploration of the development chain of some key concepts such as the definition of a ‘number’from Peano to Frege - as an example of relentless march towards bridging the chasm between consistency and completeness. Self study to look for and explain other examples6 6. Symbolic Logic: its journey from Leibnitz’s prescient programme through a long refinement by Frege, Cantor, Turing and others 7. The explosive illumination of science coupled to mathematics: quantitative verification, prediction, engineering and systems design, algorithmic explorations. Notes 1. Deduction from plausible ideas or propositions 2. Scrutiny of methods, procedures bases and criteria for their logical validity as well as of the way we use concepts 3. Empirically validated knowledge that remains tentative till supplanted by new paradigms 4. This cycle will be exemplified by analyses of the origin of ideas and hypotheses, and their evolutionary journey towards refinement, and replacement by revolutionary new Ideas: The Phlogiston theory, Newton’s constant Universe, the Ether theory, the quantum theory etc. 5. These will be worked examples and include exercise in the formulation of valid and invalid syllogistic reasoning. 6. This approach will be followed throughout

MIS04: Scientific Computing and Networking Principal Faculty: Dr G K Patra Philosophy of computing (4): Hilbert, Gödel and Turing, Church-Turing Thesis, Computability and Complexity, Quantum Computing, Quantum Entanglement and Information, Turing Machines High-performance sequential computing (6): Elementary concepts of modern computer architectures, Pipelining, Instruction level parallelism, cache performance, memory hierarchy, cache oblivious algorithms, compiler optimization issues, self tuning libraries. High Performance Computing (4): Motivating applications, parallel architectures, shared-memory parallel computing, distributed-memory parallel computing Grid Computing (4): Definition and scope of grid computing, Globus GT 3 Toolkit – Architecture, Programming model

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Cloud computing (4): Introduction to Cloud Computing, Infrastructure as a service, Platform as a service, Software as a service, Cloud applications Scientific Data Format (2): Common Data Format, GRid In Binary, Hierarchical Data Format, Network Common Data Form, IEEE standard for floating point arithmetic, little-endian and big-endian data representation Parallel Processing and programming (10): Basic concepts in parallel computing, parallel algorithms, Introduction to message passing and MPI programming, embarrassingly parallel problems, Problem decomposition, graph partitioning, and load balancing., introduction to shared memory and OpenMP programming. matrix multiplications, solving systems of equations, parallel direct and iterative methods, programming on different parallel architectures, and applications. Networking (8): Introduction to Computer Networks and Data Communications, Local Area Networks – Software and Support Systems, The Internet, DNS, Proxy, Introduction to network security, cryptography, firewalls and user authentication technologies Lab (20): Linux shell programming, High performance serial programming, compiler optimization, Multiprocessor parallel programming (MPI, SHMEM), benchmarking and performance evaluation on different architecture, Visualization of different data formats. Little-endian to big-endian conversion and vice-versa.

Suggested Readings 1. 2. 3. 4. 5. 6. 7.

Feynman, Richard P. Feynman Lectures on Computation Penguin 1999 Petzold, Charles The Annotated Turing Wiley 2008 Computer Architecture: A Quantitative Approach, by Hennessy and Patterson Foundations of Multithreaded, Parallel, and Distributed Programming, by Andrews Designing and Building Parallel Programs, by Foster Joshy Joseph & Craig Fellenstein, “Grid Computing”, Pearson/PHI PTR-2003. “Cloud Computing: Principles and Paradigms,” R. Buyya et al. (eds.), Wiley, 2010.

8. “Cloud Computing: Principles, Systems and Applications,” L. Gillam et al. (eds.) Springer, 2010. 9. Parallel Programming – Techniques and applications Using Networked Workstations and Parallel Computers, Barry Wilkinson and Michael Allen, Prentice Hall, 1999. 10. Multi-Core Programming - Increasing Performance through Software Multi-Threading, Shameem Akhter and Jason Roberts, Intel Press 2006. 11. Parallel Programming in C with MPI and OpenMP, Michael J. Quinn, McGraw Hill 2003. 12. Data Communications & Computer Networks: A Business User’s Approach, 4th Edition, Curt White, 0-619-16035-7, Course Technology

MIS05: Mathematical modeling in applications Principal Faculty: Dr. R N Singh, NGRI Steady field and potentials (Laplace, Poisson and biharmonic equations)

Gravitational potential, continuous distribution of mass; Electrostatics, charge free, point, surface and volume chargers; electrostatics, point, surface and volume sources; hydrostatics, Bernoulli equation, Stokes flow, Couette flow, Poiseuille Flow; Steady heat flow, point and distribute sources, stratified media; examples for earth system science using analytical and numerical methods. Diffusion of fields (Heat equation) Transient heat conduction, point, surface and volume sources, phase change, stratified media; Electromagnetic diffusion, sources, stratified media; pore pressure diffusion, sources, stratified Final Draft

media; stress diffusion in elastic/viscous media; Chemical diffusion, sources and chemical reactions; examples from earth system science using analytical and numerical methods. Waves fields (wave equation)

Electromagnetic harmonic waves, stratified media, waveguides, antenna; transient electromagnetic waves, sources, stratified media; harmonic elastic waves, body and surface waves, sources and free oscillations; harmonic waves in fluid media, sources, stratification; transient waves, sources in continuous media; examples from earth system science using analytical and numerical methods. Nonlinear and inverse problems

Reaction diffusion equation, travelling wave solution; population growth and dispersion; filtration equation; solitary waves; barotropic and baroclinic instabilities; parameterized climate models; parameter estimation in underdetermined systems, regularization; examples from earth system science using analytical and numerical methods. Suggested Reading Aster, R., Borchers, B. and Thurber,C. Parameter Estimation and Inverse Problems, Elsevier, 2005. Holton, J. Introduction to dynamics meteorology, Elsevier 2004 Jaupart C and Mareschal, J.-C. Heat generation and transport in the earth, 2011, CUP Marshal and Plumb, Atmosphere, ocean and climate dynamics, Elsevier, 2008 Parker, DF, Fields Flows and Waves, An introduction to continuum models, Springer, 2003 Plawsky, J. Transport phenomena fundamentals, CRC press, 2010. Torcotte and Schubert, Geodynamics, Cambridge University Press, 2002

Computational Electromagnetics Basic Electromagnetics: Maxwell’s equations, interface and boundary conditions, uniform plane wave, pointing vector, polarization, image current and equivalence principle, reciprocity theorem, surface integral equations, volume integral equations, Green’s function; Analytical Methods: Method of Separation of Variables, orthogonality condition, Eigenfunction Expansion Method, Delta function and source representation; Low-frequency Techniques: Method of Moments (MoM), Finite Difference Time Domain (FDTD), Finite Element Method (FEM), Fast Multipole Method (FMM); Resonance Method: Mei Scattering; High-frequency Techniques: Ray tracing, Integral Equation Method, Geometrical Optics (GO), Geometrical Theory of Diffraction (GTD), Uniform Theory of Diffraction (UTD), Methods of Equivalent Currents (MEC); Hybrid Methods: Mode MatchingGeneralized Scattering Matrix (MM-GSM) method, Transmission Line Transfer Matrix (TLTM) Method; Neural Network (NN) based-methods, Genetic Algorithm (GA) based methods. Suggested Readings 1. Computational Methods for Electromagnetics. A.F. Peterson, S.L. Ray, and R. Mittra, IEEE Press, NJ, 1998. 2. Analytical and Computational Methods in Electromagnetics. R. Garg, Artech House, Norwood, 2008. 3. Introduction to the Uniform Geometrical Theory of Diffraction. D.A. McNamara, C.W.I. Pistorius, and J.A.G. Malherbe, Artech House, 1990. 4. Neural Networks: A Comprehensive Foundation. S. Haykin, Prentice Hall, NJ, 1994.

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MIS 610: Introduction to Non Linear Dynamics 1. Introduction/Phase Space,Plane and Portraits (8 Lectures)  Linear Systems and their classification;  Existence and uniqueness of solutions;  Fixed points and linearization;  Stablility of equilibria;  Pendulum Oscillator,Dufing oscillator,Lindstedt`s method;  Conservative and reversible systems. 2. Limit cycles (12 Lectures)  The Van der Pol oscillator, Method of averaging;  Relaxation oscillators;  Weakly Nonlinear Oscillators;  Forced Duffing oscillator, method of multiple scales;  Forced Van der Pol oscillator,entrainment,  Mathieu`s equation, Floquet Theory, Harmonic Balance. 3. Bifurcations (9 Lectures)  Saddle-node,transcritical,and pitchfork bifurcations;  Center manifold theory;  Hopf bifurcation;  Global bifurcations; and  Poincare maps. 4. Chaotic Dynamics (10 Lectures)  Lorentz equations;  Lorentz map  Logistic map;  Lyanpunov Exponents;  Fractal sets and their dimensions;  Box ,point wise and correlation dimensions;  Strange attractors;  Forced two-well oscillators 6. Time Series Analysis (5 Lectures)  State space approach Suggested Texts Julien C.Sprott , “Chaos and Time-series Analysis”, Oxford University Press 2003; Mark Shelhamer, “Nonlinear Dynamics in Physiology: a State Space Approach”, World Scientific, 2007 Optional Texts 1. Edward Ott, “Chaos in Dynamical Systems”, Cambridge University Press, 1993 2. K.T.Alligood, T.D.Sauer, and J.A.Yorke, “CHAOS-An introduction to Dynamical Systems”, Springer, 1996

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MIS611: Advanced Information Security Divisibility, Euclidean Algorithm, Congruence’s, Finite Fields, Quadratic Residues and Reciprocity, Primality algorithm, One-way and Trapdoor Functions, Stream Ciphers, PseudoRandom Number Generators, Block Ciphers and Modes of Operations, Data Encryption Standard. Private Key Encryption, Public Key Encryption, RSA Cryptosystem, Rabin’s Public Key Cryptosystem, Knapsacks, Message Authentication and Hash Functions, Digital Signatures, RSA Digital Signature Scheme, El Gamal’s Scheme, Rabin’s Scheme. Key Distribution, Diffie-Hellman Secret Key Exchange, Two-Party and Multi-Party Protocols, Simultaneous Secret Exchange Protocol, Secret Sharing, Neural and Quantum cryptography. Cryptanalysis of cryptographic primitives and protocols, such as by side-channel attacks, differential cryptanalysis, or replay attacks; and cryptanalytic techniques on deployed systems etc. Security protocols at application level, Socket layer and Network layer, Virtual private networks. Suggested Readings 1. Bruce Schneier, Applied Cryptography: Protocols, Algorithms, and Source Code in C, Second E/d, John Wiley & Sons, 1996. 2. William Stallings, Cryptography and Network Security: Principles and Practice, Second Edition, Prentice Hall, 1998. 3. Neal Koblitz, A Course in Number Theory and Cryptography, Springer-Verlag. 4. A. J. Menezes, P. C. van Oorshot and S. A. Vanstone: Handbook of Applied Cryptography, CRC Press. 5. Shafi Goldwasser, Mihir Bellare, Lecture Notes on Cryptography. www.cse.ucsd.edu/~mihir/papers/gb.html 6. O. Goldreich, Foundations of Cryptography: Basic Tools, Cambridge University Press.

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MIS612: Scientific and Parallel Computing Philosophy of computing: The universal Turing machine, The Church–Turing Thesis, Computable and uncomputable Numbers, The printing problem and the halting problem, The halting function, The Limits of Machines, introduction to quantum computing High Performance computing: Modern computer architectures, Programming and Tuning Software, Shared-Memory Parallel Processors, Scalable Parallel Processing, Scientific data formats, introduction to grid and cloud computing and its applications, Open source software Parallel Processing and programming: Basic concepts in parallel computing, parallel algorithms, Introduction to message passing and MPI programming, embarrassingly parallel problems, Problem decomposition, graph partitioning, and load balancing, introduction to shared memory and OpenMP programming. Matrix multiplications, solving systems of equations, parallel direct and iterative methods, programming on different parallel architectures, and applications. Lab: Linux shell programming, sequential programming, compiler optimization, Multi-processor parallel programming (MPI, SHMEM), benchmarking and performance evaluation on different architecture, Visualization of different data formats. Suggested Readings 13. Philosophy of Computing and Information, Edited by Luciano Floridi, Blackwell Publisher, August 2003 14. The Temple of Quantum Computing , Riley T. Perry 2004 - 2006 15. High Performance Computing, Kevin Dowd, O'Reilly Series, 1993. 16. Introduction to High-Performance Scientific Computing ©2010 (Victor Eijkhout) 17. High Performance Computing For Dummies, Douglas Eadline, Wiley Publishing, Inc. 18. High Performance Computing: Paradigm and Infrastructure, L. Yang and M. Guo, JOHN WILEY & SONS 19. Designing and Building Parallel Programs, Ian Foster, Addison Wesley, 1995 20. MPI: The Complete Reference, Marc Snir, Steve Otto, Steven Huss-Lederman, David Walker, Jack Dongarra, The MIT press, 1996 21. How to write Parallel Programs, A first Course, By Nicholas Carriero and David Gelernter, The MIT press, 1992

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MIS 613: Cyber and Network Security Introduction to Computer Security: Introduction to techniques for defending against hostile adversaries in modern computer systems and computer networks. Operating system security, user authentication technologies, web security Mathematical Models for Internet: Design and control communication networks that respond to: randomly fluctuating demands and failures by adapting rates, by rerouting traffic and by reallocating resources, stability and fairness of rate control algorithms for the Internet; economic issues, scalable models of simulation of such networks. Digital Defense: Threats of viruses, worms, malicious codes, etc., models of propagation and their epidemic spread, dos attacks, defenses against hacking, DDoS, design of scalable test-beds for simulation of attacks against critical infrastructures, architectures for robust and flexible Internet, ubiquitous, dependable and indestructible storage. Intrusion Detection: Introduction to data and methodologies of computer intrusion detection. Statistical and machine approaches to detection of attacks on computers - Techniques for studying the Internet and estimating the number and severity of attacks, network based attacks such as probes and denial of service attacks, host based attacks such as buffer overflows and race conditions, malicious code such as virus and worms. Statistical pattern recognition for detection and classification of attacks. Techniques for visualizing network data etc. Mobile and Wireless Security: Wired/wireless networks; Effect of mobility on networks, & systems; impact on IP stack from MAC layer and up; ad-hoc and sensor networks; wireless broadcast, IP broadcast, Satellite broadcast; issues of information capacity; distinction between wired and wireless networks from information theory; Issues of security in wireless; issues of 802.11 protocols; routing in wireless networks, design of secure protocols: key distribution for access control, source authentication of transmissions, and non-repudiation; Power management and selfishness issues, attacks in wireless networks; DOS and DDOS attacks, reaction to attacks, information processing for sensor networks. Suggested Books: 1. Practical Unix & Internet Security by Gene Spafford and Simson Garfinkel, O’Reilly publication 2. Mastering Network Security, by Chris Brenton, Sybex publication, 2002 3. Network Security Hacks by Andrew Lockhart, O’Reilly publication 4. Text book “Wireless Security – Models, Threats, and Solutions,” by Nichols and Lekkas, McGraw-Hill, 2002

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MIS207

Finite Element Method

Coordinator - Prof. P Seshu

3-0-0-3

Approximate solution of linear differential equations -- Weighted residual techniques. Collocation, Least Squares and Galerkin methods. Use of piecewise continuous approximation functions. Basis of Finite Element Method. Formulation of element level equations and assembly into system level equations. One dimensional example problems. Elements of Variational calculus. Minimisation of a functional. Principle of minimum total potential. Piecewise Rayleigh - Ritz method and FEM. Comparison with weighted residual method. Two dimensional finite element formulation. Isoparametry and numerical integration. Finite element formulation for transient dynamic problems. Algorithms for solution of equations. Recommended Books 1. 2. 3. 4. 5. 6. 7.

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Bathe, K. J., Finite element procedures in Engineering Analysis, Prentice Hall of India, 1990. Cook R.D., Malkus. D. S., Plesha M. E. and Witt R. J, Concepts and Application of Finite Element Analysis, 4th Ed., John Wiley, 2005. Huebner K. H., Dewhirst D. D., Smith D. E. and Byrom T. G., The Finite Element Method for Engineers, John Wiley, New York, 2004. Reddy J. N., An Introduction to the Finite Element Method, 3rd Ed., Tata McGraw Hill, New Delhi, 2005. Seshu P., Finite Element Analysis, Prentice Hall of India, 2003. Zienkiewicz, O. C., and K. Morgan, Finite elements and approximation, John Wiley, 1983. Zienkiewicz O. C, Taylor R. L. and Zhu J Z., The Finite Element Method: Its Basis and Fundamentals, 6th Ed., Elsevier, 2005.

MIS 206 Numerical Weather Prediction Faculty: Dr V Rakesh 2-0-2-3 Governing equations - Numerical representation–numerical stebility-Computational grids Vertical Coordinates - Sub-gridscale processes (parameterizations)- Data assimilationAssimilation techniques: optimal interpolation, 3 and 4 dimensional variational data assimilation, etc.-Widely used numerical weather prediction models, their construction and application to forecasting and data assimilation - Global vs. Limited Area Models –Coupled models- Postprocessing of model output-Gridded Forecast Verification and Bias Correction - Downscaling of numerical model outputs - Ensemble Forecasting Recommended Books: Jean Coiffier 2011: Fundamentals of Numerical Weather Prediction, Cambridge University Press, 368 pp. E. Kalnay, 2002: Atmospheric Modeling, Data Assimilation and Predictability, Cambridge, 364pp. R. A. Pielke, 2002: Mesoscale Meteorological Modeling, 2ndEd., Academic, 676pp. G. J. Haltiner and R. T. Williams, 1980: Numerical Prediction and Dynamic Meteorology, 2ndEd., Wiley, 477pp. MIS 208 Statistical Physics and its Practical Applications Coordinator –Prof V K Gaur 3-0-0-3 Most Emergent (sudden appearance at some stage of evolution) phenomena in Physical, social, industrial and environmental arenas are the integral result of a host of interacting processes at varying space and time scales, and are therefore inherently stochastic. The principal challenge in dealing with such phenomena lies in our ability to reliably estimate the Canonical states of a composite system required both for enhancing our understanding of the critical stages preparatory to their emergence as well as for designing resilient mitigative measures to minimize heir adverse impacts, if any. The concepts and methodologies of Statistical Physics open up illuminating analytical approaches to addressing a host of s problems related to such emergent phenomena: Atmospheric and ocean eddies, earthquakes, epidemics, financial market crashes, to name a few. It is accordingly proposed to design and deliver a course on STATISTICAL PHYSICS AND ITS PRACTICAL APPLICATIONS as a component of the AcSIRprogramme. The following is a first cut statement of course content which would form the basis for a more detailed and more evocatively addressed context that would subsequently be brainstormed and honed. Course Contents: 1. Statistical methods: random variables, random functions, distributions, random walk, limit theorems 2. Statistical physical systems: Microscopic state of classical and quantum system, fundamental postulates of statistical mechanics, ergodic theorem 3. Microcanonical ensembles, thermal and mechanical interaction between to microscopic systems, connection between microcanonical ensemble and thermodynamics, classical monatomic gases 4. Canonical ensemble: Einstein solid, particles with two energy levels, Boltzmann gas

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5. Classical gas in canonical formalism: Ideal monatomic gas, Maxwell-Boltzmann distribution, partition function, equipartition of energy, classical monatomic gas of particles 6. The grand canonical and pressure ensembles: pressure ensemble, the grand canonical ensemble 7. Phase transition and critical phenomena: Simple fluids. Van der Wall’s equation, Landau phenomenology 8. The Ising model: Exact solution in one dimension, mean field approximation for the Ising model, The Curie-Weiss model, The Bedther-Peierls approximation 9. Scaling theories and the renormalization group: scaling theory of thermodynamic potentials, scaling of the critical correlations, The Kadanoff construction, Renormalization of iIsing model, The general scheme of the renormalization group 10. Nonequilibrium phenomena: Boltzmann’s kinetic equation, BBGKY hierarchy, Brownian motion, Langevin equation, The Fokker-Plank equation, the master equation, the kinetic Ising equation, the Monte Carlo method 11. Porous media: Relating heat, mass balance and momentum at pore scale to watershed, environmental applications 12. Data-driven modeling using statistical physics methods in nonlinear and multiscale systems: earthquakes, atmospheric instabilities, epidemics etc. Books: Salinas, SRA,. Introduction to Statistical physics, Springer, 2004. Huang, K. Statistical mechanics, J Wiley, 1987 Chandler, D. Introduction to modern statistical mechanics, Oxford Univ Press, 1987 Honerkamp,J. Statistical physics, Springer, 2002.65

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CSIR National Aerospace Laboratories (NAL)

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Engineering Electromagnetics Vectors and Fields: Coordinate systems, sinusoidally time-varying fields; Maxwell’s equations and uniform plane waves: integral form, differential form, boundary conditions, solution of wave equations; Uniform plane waves in lossless and lossy media, Poynting vector, Polarization, Reflection, Refraction, and Diffraction in Uniform Plane Waves, Normal and oblique incidence; Modes of Propagation in Waveguides: Rectangular Waveguides, Cylindrical Waveguides, Cavity Resonators; Transmission lines, Stub Matching, Smith Charts; Antenna Fundamentals: Gain, Radiation Pattern, Polarization, Effective Aperture Types of Antennas, Antenna Arrays; Microwave Sources: Klystron, Gunn diode, Travelling wave tube, Solid-state sources: IMPATT, TRAPATT, BARITT Suggested Readings 1. Electromagnetic Waves & Radiating Systems. E. D. Jordan and K.G. Balmain, 2 nd ed., Prentice Hall of India Pvt. Ltd., 1976. 2. Antenna Theory: Analysis and Design. C. A. Balanis, John Wiley & Sons, 1982. 3. Field Theory and Guided Waves. R.E. Collin, 2 nd ed., IEEE Press, NewYork, 1991.

Computational Design with Metamaterials Concepts in Metamaterials (MTM): Negative refractive index, reversal of Doppler Effect and Vavilov-Cerenkov radiation, and Snell’s law, boundary conditions; Types of MTMs: DoubleNegative (DNG) MTMs, Left Handed MTMs, Photonic Band-Gap (PBG) structures, Electromagnetic Band Gap (EBG) Metamaterials; Methods of Analysis of MTMs: Finite Difference Time Domain (FDTD), Plane Wave Method, Transfer Matrix Method (TMM), Transmission Line Method (TLM); Design of Metamaterial based radomes, Frequency Selective Surfaces (FSS) and radar absorbent structures (RAS), MTM based antenna arrays; Plasmonic nanowire metamaterial structures; Negative Refractive Index (NRI) Transmission Line (TL) lenses: Propagation characteristics, conditions for perfect imaging in the NRI-TL Lens, Reflection and Transmission through the lossless NRI-TL Lens, Super-resolving NRI Transmission-Line Lens, Aberrations; Negative Refraction and Sub-wavelength imaging in Photonic Crystals; Design in microwave, IR and optical frequency ranges. Suggested Readings 1. Negative-Refraction Metamaterials: Fundamentals Principles and Applications. ed. G.V. Eleftheriades and K.G. Balmain, IEEE Press, NJ, 2005. 2. Electromagnetic Metamaterials: Transmission Line Theory and Microwave Applications. C. Caloz and T. Itoh, IEEE Press, NJ, 2006. 3. Metamaterials: Physics and Engineering Explorations. ed. N. Engheta and R.W. Ziolkowski, IEEE Press, NJ, 2006. Final Draft

Engineering Applications of Metamaterials Design of Metamaterial (MTM) based transmission line: Theoretical background, periodically loaded Negative Refractive Index (NRI) Transmission Line (TL) MTM, dispersion characteristics, impedance match condition; Microwave devices and antennas using NRI-TL MTMs: effective medium theory, super-resolving NRI-TL lens, compact and broadband phaseshifting lines, series-fed antenna arrays with reduced beam squinting, broadband metamaterial balun, power combiners, electrically small antenna, leaky-wave backward antenna, microstrip coupler, resonators; MTM-Cloaking devices, MTM based FSS, MTM based low observable platforms, MTM based absorbent coating in IR and optical domain; Optical MTMs, Terahertz Magnetics MTMs, Surface Plasmonic MTMs, Active MTMs. Suggested Readings 1. Negative-Refraction Metamaterials: Fundamentals Principles and Applications. ed. G.V. Eleftheriades and K.G. Balmain, IEEE Press, NJ, 2005. 2. Electromagnetic Metamaterials: Transmission Line Theory and Microwave Applications. C. Caloz and T. Itoh, IEEE Press, NJ, 2006. 3. Metamaterials: Physics and Engineering Explorations. ed. N. Engheta and R.W. Ziolkowski, IEEE Press, NJ, 2006. Engineering Design of Artificial Dielectrics Basic concepts of dielectrics: Complex permittivity, dielectric loss, dielectric relaxation, dielectric breakdown. Polar and non-polar dielectrics; Polarization: Space charge polarization, dipolar polarization, ionic polarization, electronic polarization. Dielectric properties of mixtures; Lorentz theory, electrostatic solutions, evaluation of interaction constants, sphere-and disk-type artificial dielectrics, transmission line approach for disk medium, two-dimensional strip medium; Types of artificial dielectrics: anisotropic materials, bi-anisotropic materials, chiral media, honeycomb structures, inhomogeneous planar layers; Dielectric fillers, metallic wire grid/ mesh embedded structures, resonant and semi-resonant inclusions; Applications of artificial dielectrics in the design of radomes and RAS. Suggested Reading 1. Dielectrics in Electric Fields, G. G. Raju, Marcel Dekker, Inc., 2003. 2. Field Theory of Guided Waves, R. E. Collin, 2nd ed., IEEE Press, NY, 1991. 3. Analytical Modeling in Applied Electromagnetics, S. Tretyakov, Artech House, Norwood, MA, 2003.

Design and Analysis of Radar absorbing Materials (RAM) and Structures (RAS)

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Concepts in Radar cross section (RCS), Radar range equation; Stealth techniques; Radar Absorbing Materials (RAM) and its ideal requirements; Fundamental EM concepts for RAM: Maxwell’s equation, surface boundary conditions, constitutive relations, EM wave propagation through free space, homogeneous, inhomogeneous medium, EM parameters for RAM; Mathematical analysis for RAM on surfaces: Reflection at planar boundary, curved boundary, grid-based methods, high-frequency methods; EM design of RAM and Radar Absorbing Structures (RAS): narrowband absorbers, broadband absorbers, realization of RAM in practice; Absorber Characterization Techniques: measurement of material properties, free space techniques; Identification and applications of RAM; Trends in RAM. Suggested Readings 1. Radar Absorbing Materials: from Theory to Design and Characterization. K. J. Vinoy, and R. M. Jha, Kluwer Academic Publishers, Boston, MA, 1996. 2. Radar Cross Section. E. F. Knott, J. F. Shaeffer, and M. T. Tuley, Artech House, Dedham, MA, 1965. 3. Radar Cross Section Lectures. A. E. Fuhs, New York: AIAA, 1982.

Surface Modeling and Ray Tracing Applications Coordinate systems, coordinate surfaces and shaping parameters: Second degree coordinate systems, Eisenhart coordinate systems; cylindrical coordinate systems (rectangular, circularcylinder, elliptic-cylinder, parabolic-cylinder), rotational coordinate systems (spherical, prolate spheroidal, oblate spheroidal, parabolic), general coordinate systems (conical, ellipsoidal, paraboloidal); Other coordinate systems for engineering applications: Bispherical coordinate system, and ogive; Coordinates transformations, Geodesic coordinate system, Hybrids of coordinates surfaces for practical applications; Ray tracing concepts, ray casting, ray launching, Ray surface interactions, edge interactions; Applications of ray tracing: scattering characteristics, indoor/outdoor environment analysis. Suggested Readings 1. Field Theory Handbook: Including Coordinate Systems Differential Equations and their Solutions. P. Moon and D. E. Spencer, 2 nd edition, Springer-Verlag, Heidelberg, 1971. 2. An Introduction to Differential Geometry. T.J. Willmore, Oxford University Press, Oxford, 1959. Ray Tracing and Geometrical Theory of Diffraction Application of Ray tracing in various science and engineering disciplines; Overview of various ray tracing techniques; Ray-theoretic Formulation, Geometrical Optics; Scattering and diffraction, Diffraction by canonical structures, Surface-, Edge-, and Tip-diffraction; Surface modeling and Ray Tracing, Coordinate Systems and Coordinate Surfaces; Analytical Surface Generation, Geodesic coordinate system and Geodesic Constant Method (GCM); Ray tracing techniques over canonical coordinate surfaces and hybrid (composite) surfaces; Geometrical Theory of Diffraction Final Draft

(GTD) and its extensions; Ray tracing over quadric cylinders and surfaces of revolution; Ray tracing over general surfaces, including a minimum of two Seminars.

Suggested Readings 1. An Introduction to Differential Geometry. T.J. Willmore, Oxford University Press, Oxford, 1959. 2. Geometric Theory of Diffraction. Ed. R. C. Hansen, IEEE Press, New York, 1981. 3. Geometrical Theory of Diffraction for Electromagnetic Waves. G.L. James, Peter Peregrinus, Stevenage, UK, 1976.

Design of Conformal Antenna Arrays Fundamentals of conformal antennas: circular array theory; Shapes of conformal antennas: 360 degree coverage, hemispherical coverage, multifaceted surfaces; Method of analysis: electrically small surfaces, electrically large surfaces; Conformal array radiation characteristics: mechanical considerations, radiation pattern, polarization, array impedance; Geodesics on curved surfaces: singly curved surfaces, doubly curved surfaces, arbitrarily shaped surfaces, mutual coupling effect; Antenna on singly curved surfaces: aperture antennas on circular cylinders, aperture antennas on general convex cylinders, aperture antennas on faceted cylinders, aperture antennas on dielectric coated circular cylinders, microstrip-patch antennas on coated circular cylinders, conical antenna array; Conformal antennas on doubly-curved surfaces and practical shapes. Suggested Readings 1. Conformal Array Antenna Theory and Design. L. Josefsson and P. Persson, IEEE Press, NJ, 2006 Design and Analysis of Radomes Basics of radome performance parameters: Power transmission, power reflection, insertion phase delay, boresight error, antenna pattern degradations; Classification of radome wall configurations: Radome types, Classes and Styles. Monolithic and multilayered structures; Radome materials: Organic radome dielectric materials, Foam materials, inorganic radome dielectric materials, Dualmode radome materials; Radome design techniques: Constant thickness design and variable thickness designs. Broadband radome designs; Radome analysis techniques: Geometrical Optics (GO) methods, Physical Optics (PO) methods, plane wave spectrum method, finite element method, and Hybrid methods; Novel Radomes: Frequency Selective Surfaces (FSS) radomes, metamaterial radomes; Radome performance measurements: Power transmission efficiency measurements, Insertion Phase Delay (IPD) measurements, Measurements of antenna pattern degradations. Suggested Reading 1. Radar Scanners and Radomes. W. M. Cady, M. B. Karelitz, L. A. Turner, McGraw-Hill, NY, 1948. Final Draft

2. R.H.J. Cary, “Radomes,” in The Handbook of Antenna Design. A.W. Rudge, K. Milne, A.D. Olver, and P. Knight (Eds.), Peter Peregrinus, London, UK, 1982. 3. Analysis of Radome-Enclosed Antennas. D. J. Kozakoff, Artech House, Norwood, MA, 1997. 4. Frequency Selective Surfaces: Theory and Design. B.A. Munk, Wiley, New York, 2000. Airborne Antenna Analysis Introduction to Electromagnetic (EM) analysis of antennas over aircraft, missiles, satellite launch vehicles (SLV) and unmanned aerial vehicles (UAV); Introduction to Electromagnetic (EM) Scattering and Diffraction, Aerospace Scatterers, Surface Modeling, Analytical surface generation, EM Antenna Characteristics, Antenna mutual coupling and radiation pattern over aerospace scatterers; Overview of the Computational Methods, Application of the Method of Moments (MoM), Geometrical theory of diffraction (GTD), Uniform theory of diffraction (UTD), Hybrid methods; Diffraction by canonical structures; Ray-theoretic Formulation, Analytical surface generation, Geodesic Constant Method (GCM); EM Field Computations over General Quadric Cylinders (QUACYL) and Quadric Surface of Revolution (QUASOR); EM Field Computations over aerofoils, aircraft wings, SLV and UAV; Optimal antenna locations over aerospace structures, including a minimum of two Seminars. Suggested Readings 1. Geometric Theory of Diffraction. Ed. R. C. Hansen, IEEE Press, New York, 1981. 2. Conformal Array Antenna Theory and Design. L. Josefsson and P. Persson, IEEE Press, NJ, 2006

Adaptive Antenna Algorithms Adaptive antenna fundamentals, Performance parameters: Output Signal-to-noise-ratio (SNR), convergence rate, steady state analysis, Degrees of Freedoms; Beam forming networks; Antenna beam/sidelobe control; Adaptive Array Processing: Narrowband/Wideband; Sidelobe Cancellers and their performance: Conventional Generalized Sidelobe Canceller (GSC), Decision Feedback Generalized Sidelobe Canceller (DF-GSC), Blind DF-GSC; Adaptive Algorithms: Maximum Likelihood Algorithm, LMS algorithms, Recursive Least Square (RLS) algorithm, SMI algorithm; Active Cancellation in adaptive arrays; Multi-beam Adaptive Antenna Array; Correlation/Coherence between Signals; Mutual Coupling Effect; Direction-of-arrival (DoA) Estimation Methods; Adaptive antenna applications. Suggested Readings 1. Smart Antennas. L.C. Godara, CRC Press, Boca Raton, Florida, 2004. 2. Adaptive Antennas and Phased Arrays for Radar and Communications. A.J. Fenn, Artech House, Norwood, MA, 2008. 3. Smart Antennas: Adaptive Arrays, Algorithms, & Wireless Position Location. Editor: T. S. Rappaport, IEEE Press, NJ, 1998. Final Draft

4. Digital Beam Forming in Wireless communications. J. Litva and T. Lo, Artech House, Norwood, MA, 1996.

FSS Design and Analysis Fundamentals of Frequency Selective Surfaces (FSS): FSS elements, Types of FSS, dielectric loading effect, grating lobe phenomena, Wood’s anomalies; Single and multiplayer FSS, FSS structure with multiple periodicity; EM design of FSS structures: Dual-band, Multi-band, FSS performance parameters, Optimization of design and performance parameters; Methods for FSS Design and Analysis: Mode matching- Generalized-scattering matrix (MM-GSM), Method of Moments (MoM), Finite element method (FEM), Finite Difference Time Domain (FDTD) analysis, Transmission line matrix (TLM) method, Hybrid methods, Cascading of Multi-screen FSS; FSS Materials and Fabrications; Measurement Techniques; Applications of FSS: Radomes, Antennas, Radar absorbing structures (RAS). Suggested Readings 1. Frequency Selective Surfaces: Theory and Design, Ben A. Munk, John Wiley and Sons, New York 2000. 2. Frequency Selective Surfaces: Analysis and Design, ser. Electronic & Electrical Engineering Research Studies Antenna Series, J. C. Vardaxoglou, John Wiley and Sons, New York, 1997. 3. Frequency Selective Surface and Grid Array. T.K. Wu, New York: John Wiley & Sons, 1995.

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National Institute of Science Communication and Information Resources (CSIR-NISCAIR) Institute Profile National Institute of Science Communication and Information Resources (NISCAIR) came into existence

on 30 September 2002 with the merger of National Institute of Science

Communication (NISCOM) and Indian National Scientific Documentation Centre (INSDOC). Both NISCOM and INSDOC, the two premier institutes of the Council of Scientific and Industrial Research (CSIR), were devoted to dissemination and documentation of S&T information. NISCOM had been in existence for the last six decades (first as two Publication Units of CSIR, which were merged to form the Publications Division, which was later renamed as Publications & Information Directorate and in 1996, as NISCOM). Over the years, NISCOM diversified its activities, and through a host of its information products, comprising research and popular science journals, encyclopaedic publications, monographs, books, and information services, it had been reaching out to researchers, students, entrepreneurs, industrialists, agriculturists, policy planners and also the common man. INSDOC came into being in 1952 and was engaged in providing S&T information and documentation services through myriad activities such as abstracting and indexing, design and development of databases, translation, library automation, providing access to international information sources, human resource development, consultancy services in setting up modern library-cum-information centres. INSDOC was also host to the National Science Library and the SAARC Documentation Centre. Now, with the formation of NISCAIR, all the above multi-faceted activities have been amalgamated, making NISCAIR, an institute capable of serving the society using modern IT infrastructure in a more effective manner and taking up new ventures in the field of science communication, dissemination and S&T information management systems and services. Broadly the core activity of NISCAIR will be to collect/store, publish and disseminate S&T information through a mix of traditional and modern means, which will benefit different segments of society.

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Institutional Mandate To become the prime custodian of all information resources on current and traditional knowledge systems in science and technology in the country, and to promote communication in science to diverse constituents at all levels, using the most appropriate technologies. 

To provide formal linkages of communication among the scientific community in the form of research journals in different areas of S&T



To disseminate S&T information to general public, particularly school students, to inculcate interest in science among them



To collect, collate and disseminate information on plant, animal and mineral wealth of the country



To harness information technology applications in information management with particular reference to science communication and modernizing libraries



To act as a facilitator in furthering the economic, social, industrial, scientific and commercial development by providing timely access to relevant and accurate information



To develop human resources in science communication, library, documentation and information science and S&T information management systems and services



To collaborate with international institutions and organizations having objectives and goals similar to those of NISCAIR



Any other activity in consonance with the mission statement of NISCAIR

Spectrum of Activities National Institute of Science Communication and Information Resources (NISCAIR)

is

devoted to science communication, dissemination and S&T information management systems and services using modern IT infrastructure. Broadly the core activity of NISCAIR is to collect/store, publish and disseminate S&T information through a mix of traditional and modern means, which benefits different segments of society. The institute offers wide range of information services ranging from literature search to production and printing of S&T publications. The spectrums of activities covered by NISCAIR are 

Human Resource Development: NISCAIR has been providing human resource development programs on information science for the last several decades.

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Projects: NISCAIR also undertakes projects on turnkey basis for other organizations. The projects cover design and development of databases, automation and modernization of libraries, editing and production of various publications like journals, books, conference proceedings, annual reports, etc. TKDL is one of the important project where NISCAIR had shown excellence for digitizing traditional knowledges (i.e. Ayurveda, Unani, Siddha & Yoga) under modern IT environments.



Knowledge Intensive Services – NISCAIR has started a National Prior Art Search Facility service for the benefits of ideators, inventors, scientists of national research facilities and science planners in order to provide high end services like prior art search, patent drafting and patent informatics.



Editing - NISCAIR, with well-qualified and highly experienced editorial staff on its roll, provides editorial services for Conference Proceedings, Scholarly Books, Popular Science Books, etc. for other organizations on man-hour basis.



Print and Production - NISCAIR is not only self-sufficient in composing/printing of its own publications including research journals, but also takes up similar specialized jobs of other CSIR laboratories/institutions, government agencies/departments and other organizations using the state-of-the-art technology.



Graphic designing - NISCAIR has a full-fledged Art & Graphic Section with wellqualified and highly experienced staff and modern computer-based facilities like Photoshop, Corel Draw, etc.



Desk Top Publishing, being the backbone of any publishing house, NISCAIR has a strong DTP unit with latest computers, scanners, printers and specialized manpower. It undertakes not only the publications of NISCAIR, but outside jobs too on payment basis.



Literature search - NISCAIR offers literature search service and compile bibliographies on demand from indigenous as well as from international databases in the areas of S&T, engineering, industry etc



Translation service - NISCAIR provides translation of S&T documents from 20 foreign languages into English. NISCAIR also provides reverse translation (English into foreign language) also.

Departments/Divisions (A) Computational Biology & Bioinformatics (CBB) Computational Biology & Bioinformatics uses mathematical and computational approaches to address theoretical and experimental questions in biology. NISCAIR is conducting research in homology modelling, target discovery, molecular docking, and lead screening in drug Final Draft

discovery and database development. The availability of complete genome sequences of many industrially important microbes, disease causing pathogen and vast amount of structural information have stimulated many efforts to rationalize enzyme modelling and drug design. The ‘omics’ (genomics, proteomics, transcriptomics, metabolomics) together with informatics (patent informatics, bio-informatics/computational biology will speed up multidisciplinary research on enzyme modelling, structure-based drug design and epitope-driven vaccine design. NISCAIR has instituted Patent Informatics & Computational Biology Division under III (Informatics & Informetrics Initiative) since some time now (a few years). It has, as part of new initiatives in an IT regime, through data mining of patent information (>4,000/- patents approx) by suggesting possibilities for more than one dozen new tubercular drugs under the internationally known CSIR Open Source Drug Discovery (OSDD) project, under the leadership of CSIR Director General. A large number of databases have been prepared for several other critical diseases like cancer, AIDS, leishmaniasis, clean energy, Sports technologies and Nutraceuticals etc. through patent analytics. Under an innovative concept of information driven innovation, SAARC Documentation Centre has awarded a project for SAARC countries to the division. The same division runs a National Prior Art Search Services facility, which enables an inventor to cross check his invention and its patentability. A large number of inventors are finding the facility immensely rewarding. The division has embarked upon a lofty programme of educating technocrats about Intellectual Property Rights (IPR) which since long have been an arena of patent attorneys. The awareness gap on both sides was causing a lot of hardships and futile efforts causing resources drain. This crucial activity will result in faster intellectual throughput and techno-wealth generation, so much crucial for India today. The division has accessed databases like Thomson Innovation index, Qpat, Delphion, Derwent Innovation Index and software’s like Accelrys Discovery studio 3.1, VLife’s MDS etc. The division has also setup modern IT Laboratories. Considering the exciting new activity spectrum Computational Biology and Bioinformatics (CBB) has embarked upon, research and higher studies need to be regular activities. Therefore, various programmes under AcSIR are being suggested in subsequent paragraphs (see course details). Climate change informatics (CCI) CCI is associated with impact of climate change for the last one decade. During the year 2009 U.T of Lakshadweep had sanctioned a project “Development of a Database for Climate Impact Studies in India – with special reference to Lakshadweep” to CCI of NISCAIR. Field data collection and analysis related to the above project are in progress. A specific method to Final Draft

estimate the land line recession and quantity of freshwater aquifer to be contaminated due to various scenarios of sea level rise for small coral islands were developed and the same had been published in International Journals. NISCAIR had associated with various organizations to undertake climate change project in different ecosystems in the country. The Research Council of NISCAIR ha approved all the projects. The project entitled “Vulnerability Assessment and Development of Adaptation Strategies for Climate Change Impact with special reference to coasts and island ecosystems of India” (VACCIN) is a collaborative project and fourteen organizations viz. IIT, universities, CSIR Institutions are associated with it. Another project titled “Climate Change Database for Impact Assessment and Development: Adaptation and Mitigation Options for Kerala - A multi disciplinary simulation and modelling” is a collaborative program and more than fifteen organizations are associated with the project. The project titled “Climate Change Initiatives for Indian Himalayan Region (IHR) – with special reference to database, mitigation and adaptation” is a collaborative attempt with six CSIR Institutions. NISCAIR had specific facilities and tools related to Geospatial technology and climate change viz. ERDAS, Arc GIS and DGPS. The National Level training program on Climate change and Geospatial technology was organized at NISCAIR during 12-18th March 2012. Training program from various organizations.

Fifteen trainees were selected for the

Dr Rob Roggema, REMIT, Melbourne

(Australia), Dr Andrea Deri, University of London, U.K and Prof Ramesh Singh, University of Chapman, USA had given lectures. Another, International Conference on Climate Change and Environment was organized (ICCCE) as a part of the project “Development of a Database for Climate Impact Studies in India – with special reference to Lakshadweep”. It was held at Cochin University of Science and Technology during 24-26 October 2010. Many scientists from abroad Prof. Herman A Karl, University of New Hampshire (USA), Dr Ram Boojh, UNESCO representative to SAARC countries were attended. Dr Clieve Representative from World Coral Network (Australia), Dr. Tomonori Matsuura, Toyama University (Japan) were presented papers in the Conference. In addition, The International Workshop on Climate Change and Island Vulnerability (IWCCI) was held on 28-31st October 2010 at Kadmat Island, U.T of Lakshadweep. Prof Fredolin Tangang, National University of Malaysia and Vice Chairman of Intergovernmental Panel for Climate Change, Dr. Ramboojh, Program Specialist, Ecological and Earth Sciences, UNESCO Office for South Asia, Dr Leonard Sonnenschein, President, World Aquarium and Conservation for the Oceans Foundation had presented papers.

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NISCAIR publishes Indian Journal of Marine Sciences since 1972, a bi-monthly journal this multi-disciplinary journal publishes full papers and short communications in the following areas: marine biology, marine chemistry, marine geology, physical oceanography, ocean engineering, marine instrumentation, marine corrosion and material science, satellite oceanography & modelling, marine engineering, marine pollution, marine archaeology, coastal zone management. Quality statement for PhD students The indicators of quality, which are to be used for evaluating student ability and to build up their doctoral programs, will follow AcSIR guidelines.

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(A) Computational Biology & Bioinformatics (CBB) 1. Common Core (14 Credits) Every Ph.D. student, irrespective of his/her background and the programme of study, has to fulfill the following requirements. S.No. Course No.

Course Title

L-T-P-C

01.

CBB (NISCAIR)-101

Research Methodology

1-1-0-2

02.

CBB (NISCAIR)-301

Advanced Self Study

0-2-4-4

03.

CBB (NISCAIR)-401

Project Proposal writing

0-1-6-4

04.

CBB (NISCAIR)-402

CSIR-800 Societal program

0-0-8-4

2. Programme Electives (6 Credits) Any of the following courses (depending on availability) may be chosen appropriately to fulfil the total credit requirements. S.No. Course No.

Course Title

L-T-P-C

01.

CBB (NISCAIR)-201

Basic & Advance Bioinformatics

2-1-0-3

02.

CBB (NISCAIR)-202

Languages Learning in Bioinformatics

2-1-0-3

03.

CBB (NISCAIR)-203

Database Management Systems

2-1-0-3

04.

CBB (NISCAIR)-204

Discovery & Translational Bioinformatics

2-1-0-3

05.

CBB (NISCAIR)-205

2-1-0-3

06.

CBB (NISCAIR)-206

07.

CBB (NISCAIR)-207

Genomics, Metagenomics, Proteomics & Transcriptomics Computational Biology Approaches for Drug Discovery Computational Immunology / Immunoinformatics

2-1-0-3

08.

CBB (NISCAIR)-208

Computational Neurology/Neuroinformatics

2-1-0-3

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2-1-0-3

(B) Database systems & Climate Change Informatics (DBS & CCI) COMMON CORE (14 CREDIT) S.No. Course No. Title of the course

L T P C

5. DBS (NISCAIR)101

Research Methodology

1

1

0 2

6. DBS (NISCAIR)301

Advance Self Studies

0

2

4 4

7. DBS (NISCAIR)401

Project proposal Writing

0

1

6 4

8. DBS (NISCAIR)802

CSIR-800 Societal Program

0

0

8 4

Programme Electives (6 Credits) Title of the course S.No. Course No.

L T P C

11. DBS (NISCAIR)201

Data Base Management System

2

1

0 3

12. DBS (NISCAIR)202

Environment and Environmental Impact Analyses

2

1

0 3

13. DBS (NISCAIR)203

Glaciology

2

1

0 3

14. DBS (NISCAIR)204

Climatology

2

1

0 3

15. DBS (NISCAIR)205

Ecology, Remote sensing and GIS

2

1

0 3

16. DBS (NISCAIR)206

Introductory oceanography

2

1

0 3

17. DBS (NISCAIR)207

Environmental ocean technology

2

1

0 3

18. DBS (NISCAIR)208

Ocean resources

2

1

0 3

19. DBS (NISCAIR)209

Integrated coastal zone management

2

1

0 3

20. DBS (NISCAIR)210

Oceans and climate change

2

1

0 3

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(A) Computational Biology & Bioinformatics (CBB) COMMON CORE (COURSE DETAILS) (a) Course No: CBB (NISCAIR)-101

Research Methodology

(LTPC: 1-1-0-2) Course coordinators: Dr. Tarakanta Jana (Faculty : Dr. Tarakanta Jana, Shri Hasan Javed khan & Shri S. C. Sharma) Introduction, research terminology and scientific methods, different types and styles of research, role of serendipity, creativity and innovation, Scientific and critical reasoning skills, art of reading and understanding scientific papers, literature survey. Measurements in research – primary and secondary data. Quantitative methods and data analysis, biostatical analysis of data, communicating research results. Designing and implementing a research project. Ethics in research, plagiarisms, case studies. Laboratory safety issues- lab, workshop, electrical, health & fire safety, safe disposal of hazardous materials. Role & importance of science communication, effective oral and written communication, Technical report writing, research paper writing, dissertation/thesis writing, letter writing and official correspondence. Oral communications in meetings, seminars, group discussions; Use of modern tools for technical writing; Making technical presentation. Recommended Books: 1. Craig Loehle: Becoming a Successful Scientist strategic thinking for scientific discovery, Cambridge University Press. 2. Blaxter, L., Hughes, C. and Tight, M. (2001) How to do research (2nd ed.), Buckingham, Open University Press. 3. Walliman, N. (2005) Your research project: a step-by-step guide for the first-time researcher (2nd ed.), London, Sage. (b) Course No: CBB(NISCAIR)-301

Advanced Self Study (LTPC: 0-1-6-4)

Course coordinators: Dr. Tarakanta Jana (Faculty: Dr. Tarakanta Jana & Dr. G. Mahesh) Aim to train the student on learning, on one’s own topics that are not formally taught in course. This would involve primarily three components – collection of relevant literature on a chosen topic, organization of relevant material into a written report based on candidate’s own critical understanding and finally presentation of the findings in front of wide audience in the form of a seminar. Thus communication skills are also expected to be honed up. (c) Course No: CBB(NISCAIR)-401

Project Proposal Writing (LTPC: 0-1-6-4)

Course coordinators: Dr. Tarakanta Jana (Faculty: Dr. Tarakanta Jana & Dr. G. Mahesh) Two subject proposals to be prepared before comprehensive examination by selecting topics of high relevance and novelty, and will have state-of-the art review, methodologies, recommendations etc. (2 credits for one proposal) Recommended Books: 1. Janice R. Matthews, Robert W. Matthews: Successful Scientific Writing: A Step-byStep Guide for the Biological and Medical Sciences, Cambridge University Press. Final Draft

(d) Course No: CBB(NISCAIR)-402

CSIR-800 Societal Programme (LTPC: 0-0-8-4)

Course coordinators: Dr. Tarakanta Jana (Faculty: Dr. Tarakanta Jana & Dr. G. Mahesh) The students have to undertake a project in rural area for 6-8 weeks in line CSIR-800 programme which is primarily prepared at the empowering 800 millions Indian by way of S&T inventions. The theme for the project may be chosen form CSIR -800 document and as per expertise available at the individual laboratory. Students will choose the topics in consultation with Doctoral Advisory Committee (DAC). (1 credit for two practical) PROGRAMME ELECTIVES (COURSE DETAILS) Course No: CBB (NISCAIR)-201 Basic & Advance Bioinformatics (LTPC: 2-1-0-3) Course coordinator: Dr. Tarakanta Jana (Faculty : Dr. Tarakanta Jana & Expert Faculty) Course Description: Bioinformatics is amalgamation of biology, computer science, mathematics and information technology. Basic Bioinformatics comprises of gene analysis through its sequence, its structure prediction and similarity search. Advance Bioinformatics comprises Dynamics, simulation and algorithms related to genome, drug design and molecular modeling. Topics: 

Protein sequence & Structure prediction, Modeling methods, Nucleic acid sequence and Structure prediction, Evolutionary models, Gene structure prediction in prokaryotes and eukaryotes, Image analysis and Biomedical applications.



Genome sequencing, Microarray analysis, Reverse vaccinology and Immunoinformatics, Database in Immunology, Principles of B-cell and T-cell epitope prediction



Macro-molecular force fields, Geometry optimization algorithms, Various simulation techniques: Molecular mechanics, Conformational searches, Molecular Dynamics, Monte Carlo, Genetic algorithm approaches



Rigid and Semi Flexible Molecular Docking, Pdbsum, Whatcheck, Procheck, Verify3D, ProsaII, Critical assessment of Structure prediction (CASP), Structures of oligomeric proteins, Study of interaction interfaces

Recommended Books: 1. David W Mount, Bioinformatics: Sequence And Genome Analysis, 2nd Edition, cold Spring Harbour Press. 2. Durbin et al (2007) Biological Sequence Analysis: Probabilistic models of protein and Nucleic acids Cambridge University Press. 3. Thomas E. Creighton, Proteins: structures and molecular properties 4. Chemoinformatics Edited by Johann Gasteiger and Thomas Engel 5. Structural Bioinformatics, Edited Philip E. Bourne and Helge Weissig.

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Course No: CBB (NISCAIR)-202

Languages Learning in Bioinformatics (LTPC: 2-1-0-3) Course coordinators: Shri S.R. Kundu (Faculty : Shri Mukesh Pund, Mrs. Charu Verma, Shri Sanjay Burde, Shri C.B. Singh & Dr. Tarakanta Jana) Course Description: Language learning in Bioinformatics designed especially to making familiar with programming which has major role in development of software and databases in bioinformatics. Perl, Python, Ruby, XMK and MATLAB are included with intention to expert students even who have non-programming background. Topics: 

PERL Introduction, Features, Scalar Variables, Array Variables, File Handling, Lists (Arrays), Hashes (Associative Arrays), Control Structures, String Processing, Subroutines



PYTHON Introduction, Features, Python Interpreter, Control Flow Tools, Data Structures, Modules, Input and output, Errors and Exceptions, classes,



RUBY Introduction, Features, General syntax rules, classes, objects, variables, Containers, Blocks, Iterators, Loops, Branching, Arrays, Hashes, Strings, Regular Expressions, Subroutines, Exceptions, Terminal IO, File IO



XML Introduction, Need , The general structure of XML, XML Tags, Elements and sub elements, XML documents, XML attributes, Well formed XML documents, Valid XML documents, XML DTD



MATLAB Introduction, The basic features, Vectors and matrices, Built-in functions, Plotting, Programming in MATLAB, M-files: Scripts and functions, Loops, Polynomials in MATLAB, Numerical Methods

Recommended Books: 1. ‘Programming Ruby The Pragmatic Programmers’ Guide Second Edition Dave Thomas with Chad Fowler and Andy Hunt, The Pragmatic Bookshelf 2. Beginning Python, Peter Nortan, Wiley Publishing, Inc.

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Course No: CBB (NISCAIR)-203

Database Management Systems

(LTPC: 2-1-0-3) Course coordinators: Shri S.R. Kundu (Faculty : Shri Mukesh Pund, Mrs. Charu Verma, Shri Sanjay Burde, Shri C.B. Singh & Dr. Tarakanta Jana) Course Description: Database Management Systems is almost completely related to Information Technology. It is very helpful for biology background students for better understanding of framework of database. It controls creation, maintenance and use of database. This course enables students to work with databases independently and facilities for controlling data access, enforcing data integrity, managing concurrency control, and recovering the database after failures and restoring it from backup files, as well as maintaining database security. Topics: 

Database system concepts, Database system architecture, ER data model, Relational data model, Relational algebra



Tuple relational calculus, SQL, ER relational data model mapping, Indices, Relational algebra operation implementations



Query optimization, Transaction management, Serializability theory, Concurrency, Control algorithms, Recovery



Database security, Object oriented models, Object oriented databases, Data warehousing

Recommended Books: 1. Elmasri & Navathe, Fundamentals of Database Systems, Addison Wesley, 2000, Raghu ramakrishnan DBMS, Korth, Silberstaz & Sudarshan DBMS

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Course No: CBB (NISCAIR)-204

Discovery & Translational Bioinformatics (LTPC: 2-1-0-3) Course coordinator: Dr. Tarakanta Jana (Faculty: Dr. Tarakanta Jana & Expert Faculty) Course Description: ‘Discovery Informatics’ is the application of the appropriate computer science, information science and statistical tools in conjunction with domain specific scientific/engineering expertise to extract knowledge from data. New techniques and theories have been developed to address the need of diverse disciplines to obtain information from large multidimensional datasets, data streams, or complex systems. Translational Bioinformatics is a field of science in which biology, computer science, and information technology merge into a single discipline to analyze biological information using computers and statistical techniques. The use of computers in solving information problems in the life sciences. It mainly involves the creation of extensive electronic databases on genomes, protein sequences etc. Also involves techniques such as three-dimensional modeling of biomolecules and biological systems. Translational Bioinformatics is the assembly of data from genomic analysis into accessible forms. The biomedical world is so complicated (e.g., protein structural analysis, polymer conformational analysis, to name a few) and the exact structures of high molecular weight to find. It involves the application of information technology to analyze and manage large data sets resulting from gene sequencing or related techniques. The big discipline of Bioinformatics where the usage to run large programs which carry out tests for identifying drug candidates. The general science of bioinformatics is essentially it. Topics: 

Introduction to discovery Informatics, Design and development of drug discovery databases, Development of analytical tools & software, Access and utility of publicly available data sources.



Introduction to design of drug discovery database, Types of genome-scale measurements in molecular biology and genomic medicine, Analysis of microarray data, Cloud computing & clustering, Analysis of polymorphisms



Proteomics, Protein interactions, Linking genome-scale data to clinical data and phenotypes, New questions in biomedicine using bioinformatics & Case studies, Database integration



Introduction to clinical bioinformatics, Analysis of metabolic networks, Pathway analysis for drug design, Data mining, Molecular text mining, Molecular diagnosis, visualization and animation, Models for metabolic network analysis, Integrative microarray analysis, Gene networks for understanding disease

Recommended Books: 1. Discovery Informatics: Encyclopaedia of Data Warehousing and Mining, William W. Agresti (Johns Hopkins University, USA) ISBN13: 9781591405573, ISBN10: 1591405572 , EISBN13: 9781591405597 2. Translational Bioinformatics (Chapman & Hall/CRC Mathematical & Computational Biology)[Hardcover] Jake Y. Chen (Editor), Marciel G. Kann (Editor)

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Course No: CBB (NISCAIR)-205 Genomics, Metagenomics, Proteomics & Transcriptomics (LTPC: 2-1-0-3) Course coordinator: Dr. Tarakanta Jana (Faculty : Dr. Tarakanta Jana & Expert Faculty) Course Description: Genomics, Metagenomics, Proteomics & Transcriptomics are major form of Bioinformatics. From gene sequences to genome fragment assembly, to comparative genomics, to mapping gene, to building phylogenetic trees and analyzing microarray data, it would not be an exaggeration to state that computational biology is integral part of Bioinformatics. This course aid application and approaches of bioinformatics to molecular biology and increases strength to research and development. Topics 

Structure & organization of Prokaryotic and eukaryotic genome, Mitochondrial & chloroplast genome, Gene structure, SNP’s, Protein coding genes, repeated sequences, Computational approaches in comparative genomics



Genome information resources, Brief outlooks of various genome projects and their outcome, Genome rearrangements, the breakpoint graph, expected reversal distance, Algorithm for sorting by reversals, Duality theorem and genomic distance, Genome annotation, Restriction mapping



Polymerase chain reaction – principle, design of primers, RT-PCR, Multiplex PCR, Anchored PCR, Inverse-PCR and PCR walking, Molecular markers – 16S rDNA, RFLP, RAPD, AFLP, Repetitive extragenic palindromic (rep), Interspersed transcribed sequences (ITS)



Metagenomics- concepts, methodology, softwares, applications, Biodiversity Informatics – Introduction, Introduction to phylogenetic trees, Relationship of Phylogenetic analysis to sequence alignment, Unweighted pair group method with arithmetic mean (UPGMA), Evaluation of phylogenetic methods,



Transcriptomics- importance of transcription, tools and techniques in Transcriptomics, Microarray technology, Sequencing based approaches to study transcriptomes, Applications of new generation transcriptome sequencing, Gene expression profiling, Non coding RNA discovery and detection.

Recommended Books: 1. Genes and genomes by Singer.M, and Berg.P, Blackwell Scientific Publication, Oxford ,1991 2. Gene Structure and Transcription by Beebe.T, and Burke.T, Oxford Univ Press. 3. Bioinformatics – A practical guide to the analysis of Genes and Proteins – Baxevanis and Fancis Ouellette, Wiley Interscience, New York. 4. Metagenomics: Theory, methods and applications, edited by Diana Marco , Caister Academic Press. 5. Computational Molecular Biology – An algorithmic approach – Pavel A. Pevzner 6. Developmental Biology, 6th Edition, Scott F. Gilbert. 7. Genes to clone by T. A. Brown 8. Genetic engineering by S. Mitra 9. Principles of Gene Manipulation: An Introduction to Genetic Engineering by Old RW and Primrose SB. Blackwell Science Publications. Final Draft

Course No: CBB (NISCAIR)-206 Discovery

Computational Biology Approaches for Drug (LTPC: 2-1-0-3)

Course coordinators: Dr. Tarakanta Jana (Faculty: Dr. Tarakanta Jana, Dr. Vijayalakshmi & Expert Faculty) Course Description: Computational biology approaches for Drug Discovery is advance level course enabling use of chemical libraries, manipulating chemical structures in various software, drug design and development, pharmacokinetic principles, CADD tools and combinatorial chemistry. Topics 

Introduction to cheminformatics, history of cheminformatics, applications cheminformatics, Evolution of cheminformatics, Future scope of cheminformatics



Data and data source in chemistry, searching chemical structures, Representation of chemical compounds, Manipulations in 2D and 3D structures of chemical compounds and proteins, Representation of chemical reactions, Molecular descriptors, Calculations of physical and chemical data, Calculations of structural desiphers.



Development of drug, Drug life cycle, Drug development time lines, Stages of drug discovery, Strategic issues in drug discovery, Emerging approaches to drug design and discovery, Drug metabolism physic chemical properties, Pharmacokinetic action of drug on human body, Computer aided drug design, Methods of computer aided drug design



Homology modeling, Structure and Ligand design methods, Docking algorithms and programs, Drug design approaches, Strategy for target identification and validation, Lead compound identification and optimization.



Combinatorial chemistry and library design, Virtual screening, Drug likeliness and compound filters, Absorption, Distribution, Metabolism, Excretion and toxicity (ADMET) property prediction, Computer based tools for drug design.

Recommended Books: 1. Introduction to Chemoinformatics by Andrew R. Leach, Valerie J. Gillet 2. Introduction to Computational Chemistry by Frank Jensen 3. Targeted and Controlled Drug Discovery - S.P.VYAS and R.K.Khar 4. Cheminformatics By Johann Gasteiger and Thomas Engel 5. Bioinformatics from Genome to Drug By Thomas Langauer

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Course No: CBB (NISCAIR)-207

Computational Immunology / Immunoinformatics (LTPC: 2-1-0-3) Course coordinator: Dr. Tarakanta Jana (Faculty: Dr. Tarakanta Jana & Expert Faculty) Course Description: The complete genome sequences of more than 180 organisms since 1995 of which majority of them are pathogenic microbes. Concurrently, a series of new informatics tools, designed to harness this new wealth of information, have been developed. Some of these new tools allow researchers to select regions of microbial genomes that trigger immune responses. These regions, termed epitopes, are ideal components of vaccines. When the new tools are used to search for epitopes, this search is usually coupled with in vitro screening methods; an approach that has been termed computational immunology or immuno-informatics. Computational immunology is an emerging field of science that encompasses highthroughput genomic and bioinformatics approaches to immunology. Computational methods are integral to virtually every research and development project in every discipline. Immunology is not an exception and the need for sophisticated computational method for research and development in immunology is increasing. At the same time, because of the extreme domain complexity of immunology, the lag between availability of sophisticated computational methods and their implementation in this field is increasing. Researchers are now implementing these combined methods to scan genomic sequences for vaccine components. They are thereby expanding the number of different proteins that can be screened for vaccine development, while narrowing this search to those regions of the proteins that are extremely likely to induce an immune response. As the tools improve, it may soon be feasible to skip over many of the in vitro screening steps, moving directly from genome sequence to vaccine design. This course describes theoretical advances and practical applications of high throughput tools to the process of vaccine discovery. Topics  Introduction to immunology, antibody and antigens, Structural Immunoinformatics, Epitope analysis, Epitope prediction  Analysis of MHC-peptide binding, Prediction of MHC-peptide binding, Databases for Immunoinformatics, Ontologies for Immunoinformatics 

Computational modeling of immune system, Analysis of minor histocompatibility antigens, prediction of minor histocompatibility antigens. Predictive models on organ transplantation



Immunogenomics, Vaccine design, Artificial immune systems, Other biologically-inspired paradigms, Multi-agent based models of immunity, Gene networks, Systems biology in immunity, Allergenicity prediction.

Recommended Books: 1. Immunoinformatics Series: Immunomics Reviews:, Vol. 1 Schönbach, Christian; Ranganathan, Shoba; Brusic, Vladimir (Eds.) 2008 2. Immunoinformatics: Predicting Immunogenicity In Silico (Methods in Molecular Biology) by Darren R. Flower (Nov 19, 2010) 3. Immunoinformatics: Bioinformatic Strategies for Better Understanding of Immune Function (Novartis Foundation Symposia) by Novartis Foundation (Dec 8, 2003)

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Course No: CBB (NISCAIR)-208

Computational Neurology/ Neuroinformatics (LTPC: 2-1-0-3) Course coordinator: Dr. Tarakanta Jana (Faculty: Dr. Tarakanta Jana & Expert Faculty) Course Description: Neuroinformatics is a research field concerned with the organization of neuroscience data by the application of computational models and analytical tools. These areas of research are important for the integration and analysis of increasingly large-volume, highdimensional, and fine-grain experimental data. Neuroinformaticians provide computational tools, mathematical models, and create interoperable databases for clinicians and research scientists. Topics 

Introduction to Neuroinformatics, Neuronal reconstructions : from image stacks to digital vector traces, ImageJ, Neuron Morphoplug-in, Neuromantic, V3D, Neuronland, CVAPP, Neuronal reconstructions: morphometric analysis and data mining, L-Measure, neuroConstruct.



Neuroscience bioinformatics: BLAST, Swissprot, microarrays, Allen Brain Atlas, Introduction to Linux & LaTeX, Neuroinformatic Databases, Stereological measurement and online digital libraries, NIH ImageJ and the Mouse Brain Library, Quantitative Trait Loci, from Phenotype to Genotype



WebQTL, SNP filtering, from QTL to Gene, Celera Discovery System, MCI database and NCBI LocusLink, QTL analysis, Single nucleotide polymorphisms



Introducing Perl, to search for similarities between genomes, Perl and NCBI LocusLink, Realstic Neuronal Models of Pyramidal and Stellate Cells, Neuron and ModelDB, Cortical neurons

Recommended Books: 1. Neuroinformatics, G.A. Ascoli; E. de Schutter; D.N. Kennedy, Springer, ISSN: 1539-2791 2. Neuroinformatics (Methods in Molecular Biology) by Chiquito J. Crasto and S.H. Koslow (2007) 3. Databasing the Brain: From Data to Knowledge (Neuroinformatics) by Steven H. Koslow and Shankar Subramaniam (2005) 4. Computing the Brain: A Guide to Neuroinformatics by Michael A. Arbib (2001)

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(B) Database systems & Climate Change Informatics (DBS & CCI) COMMON CORE (COURSE DETAILS) Course No: DBS (NISCAIR) 101 Research Methodology (LTPC: 1-1-0-2) Course coordinators: Dr. Sundaresan J (Faculty: Dr. P D Tyagi, Dr. S C Sharma, Dr. Majumdar, Dr. Sanjay Sen Gupta, & External experts) Course Description Introduction Meaning and Objective of Researcher, Steps in Research: Identification, selection and formulation of research problem. Review of literature, Hypothesis: meaning, Characteristics and importance of hypothesis in research, Problems in formulating hypothesis, testing of hypothesis, Sampling Technique: Sampling theory-Types of sampling-Steps in sampling, sampling and Nonsampling error-Sample size, Advantages and limitations of sampling Research modelling Research Modelling: Types of Models, Model building and stages, Data consideration and testing, Heuristic and Simulation modelling. Data for Research: Primary data-Meaning-Collection methods. Observation: Interview-Questionnaire. Schedule-Pre-test-Pilot study–Experimental and case studies-Secondary data- Meaning–Relevance, limitations and cautions. Processing Data: Checking- Editing-Coding- transcriptions and Tabulation- Data analysis- Meaning and methodsQuantitative and Qualitative analysis. Statistical Techniques Statistics in Research: Specific applications of measures of Central tendency, Dispersion, Skewness and Kurtosis in research. Measures of Relationship: Correlation – Simple, Partial and multiple- Regression- Simple and multiple-Association of Attributes – applications in research. Hypothesis Testing and estimation, Standard error point, and interval estimates-Important nonparametric tests. Parametric Tests: Testing of significance mean, proportion, variance and correlation-Testing for significance of difference between means, proportions, variances and correlation coefficients. ANOVA and Chi-Square Tests: One-way and two-way ANOVA – Latin Square tests for association and goodness of fit. Measurement in Research: Measurement scales – Tests of good measurement construction of Likert and Semantic Differential scales-Source of errors in measurement- Scale validation. Research Report Structuring the Report: Chapter format- Pagination- Identification- Using: quotations- Presenting footnotes – abbreviations- Presentation of tables and figures-Referencing- Documentation-Use and format of appendices- Indexing. Research Report: Types of reports-Contents-Styles of reporting- Steps in drafting, reports-Editing the final draft-Evaluating the final draft.

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Course No: DBS (NISCAIR) 301 Advanced Self Study (LTPC: 0-1-6-4) Course coordinators: Dr. Sundaresan J (Faculty: Dr. Tarakanta Jana & Dr. G. Mahesh) Aim to train the student on learning, on one’s own topics that are not formally taught in course. This would involve primarily three components – collection of relevant literature on a chosen topic, organization of relevant material into a written report based on candidate’s own critical understanding and finally presentation of the findings in front of wide audience in the form of a seminar. Thus communication skills are also expected to be honed up. Course No: DBS (NISCAIR) 401 Project proposal writing (LTPC: 0-1-6-4) Course coordinators: Dr. Sundaresan J (Faculty: Dr. Rajeev Gupta, Dr. R S Beniwal, Dr. S. C Sharma, Dr. Sanjay Sen Gupta) Two subject proposals to be prepared before comprehensive examination by selecting topics of high relevance and novelty, and will have state-of-the art review, methodologies, recommendations etc. (2 credits for one proposal) Course No: DBS (NISCAIR)802 CSIR-800 Societal Programme (LTPC: 0-0-8-4) Course coordinators: Dr. Sundaresan J (Faculty: Dr. Majumdar, Dr. Sanjay Sen Gupta, DR Rajeev Gupta & Dr Mahesh) The students have to undertake a project in rural area for 6-8 weeks in line CSIR-800 programme which is primarily prepared at the empowering 800 millions Indian by way of S&T inventions. The theme for the project may be chosen form CSIR -800 document and as per expertise available at the individual laboratory. Students will choose the topics in consultation with Doctoral Advisory Committee (DAC).

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PROGRAMME ELECTIVES (COURSE DETAILS) Course No. DBS (NISCAIR) 201. Data Base Management System (LTPC: 2-1-0-3) Course coordinator: Dr. Sundaresan J (Faculty: Dr. Rajeev Gupta, Dr. G Mahesh & Charu Verma and external expert) Introduction Introduction- Purpose of Database Systems, Views of data, Data Models, Database language, Transaction Management, Storage Management, Database Administrator, Database Users, Overall System Structure, Different types of Database Systems Data Model E-R Model: Basic Concepts, Design Issues, Mapping Constraints, Keys, E-R Diagram, Weak Entity set, Extended E-R features, Design Of an E-R Database Schema, Reduction of an E-R schema to Tables. Relational Model: Structure of Relational Database, The Relational Algebra, The tuple relational calculus, The Domain Relational Calculus, Views. SQL- Background, Basic Structure, SET operations, Aggregate functions, Null. Values, Nested Sub queries, Derived Relations, Views, Modification of Database, Joined Relations, DDL, Other SQL features Data Transaction and Concurrency Control Transaction- Transaction Concepts, State, Implementations of Atomicity and durability, Concurrent Executions, Serializability, Recoverability, Transaction Definition in SQL. Concurrency Control- Lock based protocol, Timestamp based protocol, Validation, based protocol, Multiple Granularity, Multi version Schemes, Deadlock Handing, Insert and Delete operations, Concurrency in index structure, Query Optimization. RDBMS and Others Relational Database Design- Pitfalls in Relational-Database Design, Decomposition, Normalization , Using Functional Dependencies, and Normalization Using Multi valued Dependencies, Normalization Using Join Dependencies, Domain-Key Normal Form and Alternative Approaches to Database Design, Other Relevant Advance Topics and ApplicationsObject Oriented Database,Decision-Support Systems, Data Analysis, Data Mining, Data Warehousing, Spatial and Geographic Databases, Multimedia Databases, Mobility and Personal Databases, Information-Retrieval Systems, Distributed Information Systems, The World Wide Web. Recommended Books:

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Course No. DBS (NISCAIR) 202. Environment and EIA (LTPC: 2-1-0-3) Course coordinator: Dr. Sundaresan J (Faculty: Dr.P D Tyagi, Dr. S C Sharma, Dr. Sanajay Sen Gupta) Environment Holistic Environment- physical, chemical, biological components, socio-economic and cultural dimensions of environment, concepts of carrying capacity and global commons, Human activities and impacts: local, regional and global; short-term and long-term impacts on Environment. Environment Impact Assessment Origin and development of EIA, National environmental policy and statutory requirements of EIA; objectives of EIA. EIA Analysis Methodology of EIA; scoping, categorization and evaluation criteria; prediction and assessment of impact, interactions between environmental components and impacts. Alternate strategies and mitigation measures, environmental monitoring and audit. Case Studies Urban development, water resources development, Oceanographic, Glaciers studies, Impacts on critical habitats-Marine and Terrestrial. Recommended Books: 1. Introduction to Environmental Science by Eric Pallant and Terrence Bensel. 2. Environmental Impact Assessment: A Practical Guide by Betty Marriott. 3. Introduction to environmental impact assessment by John Glasson, Riki Therivel, Andrew Chadwick

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Course No. DBS (NISCAIR) 203. Glaciology (LTPC: 2-1-0-3) Course coordinator: Dr. Sundaresan J (Faculty: Dr. Pankaj Gupta and External Expert) Introduction Glacier, importance and implication of glaciological studies, Cryosphere, inventory of himalayan glaciers, identification system of glaciers, Glacial Geomorphology Glacial geomorphology, glacial deposits and paleoglaciation, hydrometry glaciated basins, suspended sediment transport, mass balance studies- net balance, ablation measurement, accumulation measurement, snow density measurement, relationship of mass balance to climate, snow melt processes Glacial Physics Physics of ice and snow, mechanics of snow/ice creep, ice crystals, engineering properties of glacial materials, glacial hydrochemistry Satellite glaciology Application of remote sensing techniques in glaciology, application of advance surveying techniques, global positioning system, geodetic techniques. Recommended Books: 1. Physics of Glaciers, Third Edition W. S. B. Paterson. 2. Glaciology Introduction :Non-Polar Ice Cap, Glaciers of Bhutan, Farm Creek Section, Glacial Lake, AR Te, Wedgwood Rock, Glacier Morphology

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Course No. DBS (NISCAIR) 204.Climatology (LTPC: 2-1-0-3) Course coordinator: Dr. Sundaresan J (Faculty: Dr. Rajendran, Dr. Sanjay Sen Gupta & External experts) Introduction Definition of weather and climate; climatology origin, composition and structure of atmosphere. solar radiation, heat budget and temperature distribution. atmospheric pressure and its distribution pattern. Atmospheric Circulation General circulation and planetary winds, walker circulation- enso and la nina, origin of monsoons and jet streams. Atmospheric moisture: humidity, evaporation, condensation. precipitation: dynamics and types of precipitation. stability and instability of atmosphere, air masses and fronts. air masses and fronts. weather systems : extra tropical and tropical cyclones. Climate Classification and Modelling climatic classification: basis of climatic classification by koeppen, trewartha and thornthwaites. climatic changes- evidences and explanations. global warming and its impacts. mitigation and adaptation. Climate Modeling Introduction to basic equations for the atmosphere. Brief overview of hierarchy of models. Numerical methods: finite difference, spectral and semiLagrangian techniques. Model physics: parameterization of subgrid-scale phenomena such as cloud-convection, land- surface processes, boundary-layer effects and radiation. Introduction to coupling with ocean models Satellite Meterology Satellite Meteorology Introduction to radiative transfer; radiative properties of surface; radiative properties of the atmosphere; scattering of radiation; image analysis; thermal, infrared and microwave techniques for measurement of temperature, humidity and cloud height; atmospheric sounders, limb sounding, radiation budget. Recommended Books: 1. Introduction to climate dynamics and climate modeling Goosse H., P.Y. Barriat, W. Lefebvre, M.F. Loutre and V. Zunz, (date of view). 2. Introduction to climatology for the tropics by J. O. Ayoade

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Course No. DBS (NISCAIR) 205. Ecology, Remote sensing and GIS (LTPC: 2-1-0-3) Course coordinator: Dr. Sundaresan J (Faculty:DR J Sundaresan, Dr R.S Benniwal & Dr. Panksj Gupta,) Ecology and Ecosystem Based Management Introduction, Concepts, Life processes and adaptations, Distribution and abundance of organisms, the movement of materials and energy through living communities, Ecosystem based management, EBM Tools. The successional development of ecosystems, and the abundance and distribution of biodiversity in context of the environment. Bio geographic classification- Bio geographic zone, Province, Region and Biome, Remote Sensing Introduction, Basics of Remote Sensing, and Aerial Photography. Electro Magnetic Spectrum, Law of Radiation, Atmospheric interaction, Remote Sensing System, Spectral Reflectance, Resolution, Orbit and Platform, Remote Sensing Satellites, Principle of Thermal and Microwave imaging. Visual Image Interpretation, Image Processing, Image Classification, Remote Sensing Application Geographical Information System GIS, Coordinate System and Projections, Spatial Analyst, Geo-statistical Analysis, Spatial Statistics, Geo-Data Base, DGPS-GIS Applications. Recommended Books: 1. Science of Ecosystem-based Management: Narragansett Bay in the 21st Century Alan Desbonnet, Barry A. 2. Remote Sensing of the Environment and Earth Resource Perspective John R. R. Jensen 3. An Introductory Digital Image Processing: A Remote Sensing Perspective John R. Jensen 4. Computer Processing of Remotely Sensed Images: An Introduction Paul M. Mather,Paul Mather 5. Laser Remote Sensing of the Ocean : Methods and ApplicationsKonstantin I. Voliak,Alexey F. Bunkin 6. Remote Sensing and Image InterpretationThomas M. Lillesand,Ralph W. Kiefer 7. Extensively illustrated, this updated edition provides a balance between classical visual image interpretation and digital image processing techniques. 8. GIS: A Visual Approach. Bruce Ellsworth Davis,Bruce Davis

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Course No. DBS (NISCAIR) 206. Introductory Oceanography (LTPC: 2-1-0-3) Course coordinator: Dr. Sundaresan J (Faculty: Dr.Sundaresan J and Dr Rajendran) General introduction – history of oceanography – expeditions - geomorphology and structures of the ocean floor, Continental slope and shelf - physical properties of sea water- distribution, of temperature, salinity, density and oxygen in space and time - acoustical and optical characteristics of seawater – color of the sea. Ocean waves and tides. Significant wave height and period, wave spectrum, principles of wave forecasting - wave data and measurement techniques. Water masses: formation and classification - T-S diagram – water masses of the world oceans – Indian Ocean water masses - identification of water masses. Circulation: general circulation of the atmosphere –– Ekman spiral – wind-driven circulation - currents in the oceans – upwelling thermohaline circulation - El-Nino and La-Nina. Heat budget of ocean: insolation – long wave radiation – effect of clouds – sensible and latent heat transfer- Bowen’s ratio – ocean heat transport – spatio - temporal variability of heat budget terms and net heat balance. Recommended Books: 1. Descriptive Physical Oceanography: G.L.Pickard and W. J. Emery, Pergamon, 5th edn., 1992. 2. Descriptive Physical Oceanography: M.P.M.Reddy, Balkema, 1st edn., 2001. 3. The Oceans: H.U. Sverdrup, Prentice Hall, 1st edn., 1942 4. Principles of Physical Oceanography: G.Neumann & WJ Pierson, Jr., Prentice Hall,1st edn.,1966. 5. Encyclopedia of Oceanography: Fairbridge, Reinhold, 1st edn., 1979. 6. Physical Oceanography Vol.I & II: A Defant, Pergamon Press, 1st edn., 1961. 7. Ocean Currents: G. Neumann, Elsevier, 1st edn., 1968. 8. Regional Oceanography: Tomczak M. & J.S.Godfrey, 9. Ocean Circulation & Climate: Siedler, Church & Gould, Academic Press, 1st edn., 2001. 10. Foundations of Fluid Mechanics: S.W.Yuan, Prentice-Hall, 1st edn., 1970 11. Physical Fluid Mechanics : D.J. Tritton, Oxford Science Pub., 2nd edn., 1978. 12. Fluid Mechanics : W. Kaufman, Wiley, 1st edn., 1954. 13. Geophysical Fluid Dynamics : J. Pedlosky, Springer Verlag, 2nd edn., 1982. 14. Fundamentals of Acoustics: L.E.Kinsler and A.R.Frey, John Wiley, 3rd edn., 1982. 15. Ocean Acoustics : Tolstoy and Clay, McGraw Hill, 1ste dn., 1966.

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COURSE NO. DBS (NISCAIR) 207. Environmental Ocean Technology (LTPC: 2-1-0-3) Course coordinator: Dr. Sundaresan J (Faculty: Dr. Sundaresan J and External experts) Pollution of air, soil and water. Causes of pollution. Common pollutants- solid waste, liquid waste and gaseous wastes. Fate of various pollutants. Pollution of marine environment. Standards for natural, inland and marine waters. Technological Control measures- Design of control systems EIA studies. Marine corrosion: Fundamental factors affecting corrosion of metals in water. Marine Environmental aspects - different forms of corrosion – pitting, bimetallic (galvanic) corrosion, and deposit attack. Design of corrosion control devices – practical field considerations anticorrosive and antifouling technology. Energy from the sea. Waves, tide, OTEC, Osmosis, Solar and wind energy systems. Operational aspects and oceanographic factors, new technologies, design and applications, case studies. Marine Information systems, Data management and dissemination of information, feedback and updating mechanisms. Marine surveillance. Law of the sea. Current legislation on the exploitation of the ocean resources, the maritime zones, territorial zones, EEZ, Sea Bed Authority, legal principles for conduct of marine scientific research. Recommended Books: 1. Advances in Water Pollution Research: B.A.Southgate, Proc. London, 1962. 2. Remote sensing for the Control of Marine Pollution Vol6: Jean Marie Massin, NATO, 1984. 3. Marine Environmental Pollution 2: Richard A, Geyer, Elsevier, 2nd edn., 1999. 4. Marine and Off shore Corrosion: Kenneth A Chandler, Butterworth, London, 1st edn., 1985. 5. Corrosion Engg. : Fontana & Greene, Tata McGraw Hill, 3rd edn., 1998. 6. Hand book of Oceanographic Engg.Materials: Stephen G. Dexter, Wiley, 1st edn., 1979. 7. Cathodic Protection , Theory andPractice :V. Ashworth & C.J.L. Booker, Ellis Harwood, 1st edn., 1986. 8. Corrosion in Marine Environment :D.H.Deere, John Wiley, 1st edn., 1977. 9. Bio-deterioration of Materials :A. Harry Walters and John J, Elsevier, 1st edn., 1968. 10. Metals hand book, American Society for Metals :International Metals Park, Uty Michigan, 1st edn., 1987. 11. Ocean Wave Energy Conversion :Michael E. Mc Cormick, Wiley, 1st edn., 1981. 12. Wave Energy - a Design Challenge :R.Shaw, Halsted Press, 1st edn., 1982. 13. Tidal Power :Institution of Civil Engineers, U.K, Plenum, 1st edn., 1972. 14. Ocean Engg. - Goals,Environmental Technology :J.F. Brahtz, Wiley, 1st edn., 1968.

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COURSE NO. DBS (NISCAIR) 208. OCEAN RESOURCES (LTPC: 2-1-0-3) Course coordinator: Dr. Sundaresan J (Faculty: Dr. Sundaresan J and Dr Pankaj Gupta) Ocean Resources: definition and classification, potential uses of sea. Geophysical and oceanographic operations: direct and indirect methods of data collection on and below sea surface, Involvement of ocean scientists in exploration and exploitation, phases of marine resources. Operational requirements, ports and harbors, vehicle requirements, planning and policy on ocean resources, harvesting food from the sea, extracting or dredging raw materials, sea as a highway, energy generation, military exercises, leisure and tourism, sewage and waste disposal. Understanding the hostile marine environments, mineral and hydrocarbon resources, exploration, development, and production of hydrocarbons, ocean mining, semi-submersible and their functions, stability, motion and weight. The ice environment and operations in extreme weather conditions, offshore safety and rescue. Use of marine robotics and expert systems, machine based operations for solving strategic resource issues. Recommended Books: 1. The Oceans, Our future :M Soares, Cambridge Univ. Press, 1978. 2. Oceanology Vol. 6 :Soc. Underwater Technology, Graham & Trotman, 1988. 3. Descriptive Physical Oceanography :W J Pierson and G Neumann, Pergamon, 5th edn., 1990. 4. Mining Engineers Handbook, Vol. 2 :Teele, John Wiley, 2nd edn., 1996. 5. Introduction to mineral Exploitation :Antony M Evans, Wiley, 3rd edn., 1990. 6. Coastal and Deep Ocean Dredging :John B Herbich, Gulf Pub. 1st edn., 1975. 7. The Sustainable Management of 8. Tropical Catchments :Harper & Brown, Wiley 1st edn., 1999. 9. The Ocean Basins and Margins :Dercourt, Plenum, Vol.8, 1996. 10. Introduction to Energy Resources, 11. Technology and Society :E S Cassdy, Elsevier, 1st edn., 2000. 12. Underwater Minerals : D S Cronon, Academic Press, 1st edn., 1980. 13. Ocean Year Book (Vol 1 – 4) : Borges & Ginsburg, The University of Chicago Press, 1983. 14. Mineral Wealth of the Ocean : Ghosh & Mukhopadyay, Oxford & IBH Pub. Co., 2nd, 1999.

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COURSE NO. DBS (NISCAIR) 209. INTEGRATED COASTAL ZONE MANAGEMENT (LTPC: 2-1-0-3) Course coordinator: Dr. Sundaresan J (Faculty: Dr. Sundaresan J) Coastal zone management – concepts, definition and techniques. Approach to CZM. Nature of coastal zones of the world. Development and Conservation activities. Resource management of coastal regions. Matrix on CZM. Systems approach. Balanced budget on use and preservation of resources of the coastal zone. Coastal ocean processes and CZM. Coastal features and marine influence on coastal development. Acts and legislation on CZM. Implementation of policies. Traditional practices, values and emerging modern technological innovation. Case studies. Planning and developmental approaches in CZM. Current practices and Future outlook. Coastal vulnerability. Methods for evaluation of coastal status. Sustainable development of coastal zone. Recommended Books: 1. CZM : Brathz Ecosystems at the Land Sea Margins – Drainage Basin to Coastal Seas : Thomas, Smodlaka & Turner, AGU, 1st edn., 1999. 2. Large Scale Constructions in Coastal Environments : Vollmer and Grann, Springer Verlag, 1st edn., 1998. 3. Fluvial Process and Environmental change: Brown, John Wiley, 1st edn., 1999. 4. Coastal Erosion – Response and Management : Charlier and Meyer, Springer Verlag, 1st edn., 1998. 5. Mixing in Estuaries and Coastal Seas : Pattiaratchi, AGU, 1996. 6. Coastal Zone Management -Coastal Management : Salomons, Springer, 1st edn., 2001. 7. Coastal Zone Management (2 Vol.) : Korakandy Kalpaz Publications, 1st edn., 2005 8. Gis For Coastal Zone Management : Bartlett Darius, CRC Press, 1st edn., 2003. 9. Introduction -Coastal Zone Management : Beatley Timothy, Island Press, 1st edn., 2002. 10. ICZM for Coral Reefs: Decision Support Modeling : Gustavson, Huber, Ruitenbeek, World Bank Pub., 1999. 11. Integrated Coastal Zone Management (ICZM) The Global Challenge : R R Krishnamurthy, Research Pub. Services, 2002. 12. Coastal Planning and Management: Robert Kay, Taylor & Francis, 2nd edn., 2005

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COURSE NO. DBS (NISCAIR) 210. OCEANS and CLIMATE CHANGE (LTPC: 2-1-0-3) Course coordinator: Dr. Sundaresan J (Faculty: Dr. Sundaresan J, Dr. Rajendran) Role of oceans in climate - Indicators of climate change – short and long term observations – IPCC and results – Forecast and Predictions – Study on parameters related to climate change. Signals from study of Temperature, global warming, role of carbon-di-oxide content and related gases, sea level changes. SST and precipitation features, weather conditions and marine ecosystems – ongoing projects in climate change studies. The ocean conveyor belt – influence on circulation patterns – The Carbon cycle – responses from ecological systems – Impacts - Human interventions – Robust findings and key uncertainties. References: 1. Climate Change 1992 : Report – IPCC, J T Houghton, C A, Callander & S K Varney 2. Climate Change 2001, 2008 : Synthesis Report – IPCC, 2002, 2008 3. Climate Process and Change :E Bryant, Cambridge Univ. Press, 1st edn., 1997. 4. Global Environmental Change– Past, Present and future : K K Turekian, Prentice Hall, 1st edn., 1996. 5. Global Warming – The Complete Briefing :J Houghton, Cambridge Univ. Press, 1st edn., 1997. 6. Assessing the impact of Climate Change on Natural Resource System: Frederick & Rosenberg, Kulwer Academic, 1st edn., 1994.

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National Institute of Science, Technology and Development Studies (NISTADS) Course Title: Science, Technology and Innovation Studies (STIS) NISTADS, the one and only social sciences research lab under the CSIR (Government of India) is an academic pioneer and a policy beacon. It embodies the nation’s commitment to understanding and steering the complex relationships between science and society. The purpose of this STIS course offered by NISTADS, is to create a critical mass of scholars and practitioners with analytical competencies to lead and transform India’s science, technology and innovation trajectories in economically productive, socially progressive and environmentally sustainable ways. In its academic and policy endeavours, CSIR-NISTADS operates at the interface between science and society. Through this STIS course, the research and policy expertise and experience in NISTADS will be shared with and built into a wide range of natural, physical and social science graduates. Their theoretical as well as empirical skills will ensure that they become future managers in cutting-edge S&T based industry, knowledge entrepreneurs and bureaucrats in development sectors ranging from agriculture to energy to space science, and policy analysts and advisors in national and international spheres. The state, the market and several other social, political and cultural agencies influence and shape both science and society – analysing these interactions and causal relationships demands inter-and trans-disciplinary competence. How can we enable innovation for inclusive and harmonious economic growth? How do we prioritise our scientific research effort? What are the most effective technology commercialisation strategies available, and what are the criteria to choose the best in given contexts? How do we measure and assess scientific performance? With India’s political, scientific and industrial leadership demanding these skills, this course will assemble and anneal a new inter-disciplinary and visionary generation capable of and committed to knowledge based sustainable development. This demand inspires the proposed theme of “Science, Technology, and Innovation Studies” (STIS) for the NISTADS program for Ph.D. The course curricula appropriate for STIS are currently under preparation. Broad outline of the provisional seven core courses are already drafted. Outline of twenty five optional courses have been proposed provisionally of which four courses are also drafted as samples. Details of each course would be further prepared. Since compulsory courses will require one year time (two semesters) to complete, by that time other optional courses would be developed. NISTADS proposes to take students from all disciplines of social sciences who have an M.Phil or equivalent or who otherwise have qualified for the U.G.C. or equivalent including CAT, and also students from natural sciences and engineering and medicine who have qualified similar tests such as of the CSIR or GATE, and who are desirous of cross-disciplinary instruction. NISTADS is also willing to collaborate with other CSIR laboratories.

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Brief and provisional outline of Course Contents & Structure On the basis of the feedback from the scientists the following courses provisionally being proposed: a. Core courses 1. Quantitative Research Methodology – focuses on introductory statistical/econometric tools that are usually used for analysis of research question 2. Introduction to Qualitative Research 3. Indian Economy & Policy (focuses on the transition of Indian economy and her major policies since independence) 4. Innovation systems and development 5. Introduction to History of Science 6. Science & Technology Policy (focuses on policy aspects relating science and technology in India and other emerging economies) 7. Science and Technology Systems - India and the World b. Optional courses 1. Trade & Technology (focus on the interplay between international trade, policy, FDI and technology diffusion) 2. Enterprise Development through Value Chains Analysis (EDVCA) 3. Intellectual Property Rights in the Context of Research, Innovation and Development 4. Environmental History 5. Resource Planning & Policy (RPP) 6. Institutional

Economics

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functioning/behaviour) 7. Advanced Econometrics 8. Law & Economics 9. Public Policy (focuses on contours of public policy formation in general and India in particular together with evaluation of their welfare implication and implementation issues) 10. Economic and Systems Modelling for Policy Analysis (focuses on different approaches to economic modelling and their use in policy analysis) 11. Organisation & Innovation (focuses on various organisational forms and their linkages with innovation) 12. Game Theory & Social Application (focuses on basics of game theory and their application in different social problems) 13. Indian Business History Final Draft

14. Technology Valuation and Financing (focuses on methods of technology evaluation and financing principles) 15. Risk, Technology and Policy (focuses on capacity building for (a) analysing the relationship between the three (risk, technology and policy), and (b) using different methods for risk assessment (ex-ante and ex-post) for different contexts (social, environmental, economic, etc.) and scenarios). 16. Science, Technology and Innovation for Rural Transformation (focuses on theoretical debates about knowledge and development, and building analytical capabilities for S&T policy and innovation for rural development 17. Science, Technology and Innovation for Industries 18. Science, Technology and Innovation for Services 19. Technology, Labour and Employment (focuses on technology development, skills, labour productivity and employment) 20. Sociology of Science 21. Macro Economic Policy (focuses on in-depth study of macroeconomics) 22. Soft Computing 23. Science, Philosophy and Ethics 24. Industrial Organisation and Technology Regulation (focuses on key concepts and models of industrial organisation and how regulations relating to technology impinge on the system) 25. Science, innovation and politics

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Core Course - 1 Course Title: Quantitative Research Methodology Coordinators: Yogesh Suman Lecture-Tutorial- Practical-Credit: 1-1-1- 1 Total Teaching Hour: (8 Hr. Lecture, and 4.5 Hrs. Practical + Tutorial) Objective: The purpose is to make students capable in identifying research questions and formulating hypotheses clearly and accurately; in context of a research issue. This would help them in identifying proper data collection and analysis techniques. This will be followed by providing them thorough understanding of standard quantitative techniques. Topics & Subtopics: 1. Introduction (1.30 Hrs.)  Quantitative data principals  Types of data-Binary, nominal, interval, ratio, ordinal  Inferential statistics  Descriptive statistics  Population and parameter 2. Sampling (1.30 Hrs.+ 1.30 Practical/Tutorial)  Sample and Statistics  Importance of sampling  Sample Size Determination 3. Sampling Techniques  Non probability Sampling Techniques o Convenience Sampling o Judgmental Sampling o Quota Sampling o Snowball Sampling  Probability Sampling Techniques o Simple Random Sampling o Systematic Sampling o Stratified Sampling o Cluster Sampling 4. Hypotheses Formulation and Testing (1 hr.+1.30 hr Practical/Tutorial)  Definition of Hypotheses  Null and Alternative Hypotheses  Critical Z values and Rejection regions  Z-Table for Normal distribution  Two Tailed Test  Right Tailed Test  Left Tailed Test 5. ANOVA (1 hr.)  Principal behind ANOVA  Sum of Squares Final Draft

 Mean Sum of Squares  ANOVA Table 6. Regression (1 hr.)  Simple Regression And Correlation  Simply linear regression Model  Multiple regression 7. Chi Square Test (1 hr.) 8. Factor Analysis (1 hr. + 1.30 hr. practical/tutorial) Suggested Readings 1. Allen L. Webster Applied statistics for Business and Economics: An Essentials version (Third Edition), McGraw-Hill. 2. Kothari, C. R. Quantitative Techniques, Vikas Publishing House. 3. Gupta, R. P. Quantitative Techniques, Daya Publishing House.

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Core Course - 2 Course Title: Introduction to Qualitative Research Coordinators: Yogesh Suman Lecture-Tutorial- Practical-Credit: 1-1-1-1 Total Teaching Hour: 15.5 Hrs. (10 Hr. Theory, 5.5 Hr. Practical + Tutorial) Objective: The objective of the course is to provide students deep insight of research methodology in context of social science research. Practical illustrations from the projects done by the faculty will also be given by explaining background reasons for adopting a particular technique. Topics & Subtopics: 1. Introduction (1.30 Hrs.)  Types of research  Pure research  Applied research  Policy research  Action research  Model for research (Examples of each type of research)  Characteristic of Qualitative Research  When to use qualitative research  Designing a qualitative study 2. Approaches to Qualitative research (1.30 Hrs. + 3 Hr. Practical/Tutorial)  Narrative research o Types of narrative research o Procedures for conducting narrative research  Phenomenological research o Types of phenomenology o Procedures for conducting phenomenological research  Grounded theory research, o Types of grounded theory studies o Procedure for conducting grounded theory research  Challenges, ethnographic research o Types of ethnographies o Procedure for conducting ethnographic study  Case study research o Procedure for conducting a case study  Choosing an approach to qualitative research.  Qualitative data principals 3. Conducting interview (1.30 Hr. + 1 Hr. Practical/Tutorial)  Unstructured Interviews  Semi structured interview  Structured interview 4. Sociometry(1 Hr.) 5. Validity (1 Hr.)  Types of Validity,  Internal validity, Final Draft

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8. 9.

 Construct validity  External validity  Statistical validity  Threats to validity Non Experimental research ( 2 Hrs. + 1.30 Hr Practical/Tutorial)  Observational  Naturalistic observation  Survey research o Designing a questionnaire o types of questions o Methods of administering questionnaire o Problems of response rate o Data analysis Experimental research (1 Hr.)  Attributes and variables  Cause and effect  Control  Types of experimental design Quasi experimental (30 Min.) Ex post facto research.(30 Min)

Suggested Readings 1. Creswell, John W. Qualitative Inquiry and Research Design Choosing among Five Approaches, Sage Publications. 2. Guthrie, Gerard. Basic Research Methods, Sage Publications. 4. McBurney, Donald H and Thomson-Wadsworth. Research Methods. 5. Kothari, C.R. Research Methodology - Methods and Techniques, New Age International (P) Limited Publishers, Ansari Road Darya Ganj, New Delhi-110002. 6. Fetterman, David M. Ethnography: Step-by-Step (Applied Social Research Methods), Sage Publications. 7. Gibbs, Graham. Analysing Qualitative Data (Qualitative Research Kit), Sage Publications.

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Core Course - 3 Course Title: Indian Economy and Policy Coordinators: Dr Pradip Kumar Biswas & Dr Sanjib Pohit Lecture-Tutorial- Practical-Credit:

2–1–0–3

Total Teaching Hour: 50 Objective: The course intends to provide the students an overview of the Indian economy, its development and evolutionary process since independence. Topics & Subtopics: 1. State of Indian economy at the time of independence with a brief discussion on colonial era 2. Planning Era  Need for planning  Planning Strategies under different plans 3. Agricultural Polices  Policy frames in the 1950s and the early 1960s  Policy shifts in late 1960s – green evolution strategies  Policy changes in the 1980s – diffusion of green revolution across crops, regions  Land holding structure, tenancy and technology change  Credit and insurance  Research and development  Current issues of importance 4. Industrial Policies  Policy frames in the 1950s to 1970s  Structural retrogression of Indian Industries in mid 1960s  Policies for SMEs and large industries  Economic liberation and end of license raj  Indian industries in the globalized world 5. Structure and Growth of the Service Sector 6. Policy support for technology diffusion and innovation 7. The External Sector  Indian Trade Policy and Development  India’s Balanced of Payments – Emerging issues  Openness and FDI flows Suggested Readings

nd

1. Roy, Tirthankar, The Economic History of India 1857-1947 (2 edition, 2008). Chapter 3 pp.73-89; pp.97-102. 2. Chakravarty S. (1987) Development Planning: The Indian Experience, Clarendon Press, Oxford. 3. Government of India, Planning Commission, Second Five Year Plan, and various other five-year plan documents.

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4. Mohan, Rakesh (2003). “SSI Policy in India: A Critical Evaluation,” in A.O. Krueger (ed.), Economic Policy Reforms and the Indian Economy, Univ. of Chicago Press. 5. Nagaraj R. (2003). “Industrial Policy and Performance since 1980”, Economic and Political Weekly, Aug.30-Sep.7 6. Goldar, Bishwanath (2004). “Indian Manufacturing: Productivity Trends in Pre- and PostReform Periods,” Nov. 20, Economic and Political Weekly. 7. Manoj Pant and Manoranjan Pattanayak (2005). “Does Openness Promote Competition? A Case Study of Indian Manufacturing,” Economic and Political Weekly, Sept. 24. 8. Aditya Bhattacharjea (2006), Labour Market Regulation and Industrial Performance in India, A Critical Review of the Empirical Evidence, CDE, Working Paper No.141

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Core Course - 4 Course title: Innovation systems and development Coordinator: Dr. Rajeswari S. Raina Lecture –Tutorial-Practical-Credit: 2-1-0-3 Total teaching hours: 50 Objective: This course is to help students develop their analytical skills in understanding and enabling innovation to meet development goals. It is designed with the core courses, tutorials and one practical exercise (a case analysis or project) that can be selected by the students depending on their disciplinary orientation, context or work experience. The use of innovation systems framework for planning and its operationalization for development demands theoretical insights and analytical competencies. This course will give students a clear understanding about the difference between (a) innovation systems, (b) technology and society, and (c) social construction/mode of knowledge production. That the components and systems relationships – interactive learning, the academic (disciplinary) contexts and policy contents, and processes involved in the analysis of each of these are different, will be made explicit. Despite increasing currency of the term innovation (as seen in India in the past three years or so), many continue to use the term as synonymous and the epistemic equivalent of technology or technology generation and diffusion. Through the lectures and tutorials in this course, the students get to use the innovation systems theoretical framework and the analytical instruments offered by several disciplines – economics, sociology, anthropology and political science in particular, to understand and enable innovation that can lead to development outcomes. The normative positions being more explicit in the innovation systems framework, helps the students see and question the assumptions made in mainstream economics and technological or technology commercialisation studies therein. Covering a range of economic – Marshallian neo-classical and Marxist historical materialism, Schumpeterian evolutionary, Veblenian/Kapp institutional and evolutionary, and sociological – Feenbergian critical theory, Latourian social construction vs. Bijker-Winner social determinism, theories and analytical tools, the course sets a terrain in which the student can use the analytical narrative of the innovation systems framework to achieve development goals. In the main semester, besides 50 hours of lecture, the course will have two tutorials. Each lecture (3 hours each) will also include discussion of the reading material. The students will be taught the basic skills of building an annotated bibliography, the design of a conceptual framework, etc. Topics and sub-topics 1. Introducing Innovation Systems – basic definitions, framework (1 Lecture) 2. Distinguishing features – Components and processes in Innovation systems (1 Lecture) 3. Differences between innovation systems framework and technology and society (1 Lecture) 4. Major questions asked – debate on the use in planning (interventions or investments) for development (1 Lecture) o Tutorial – students read and review in class three major books in Innovation Systems literature 5. Development economics – Innovation systems theory – as two estates (1 Lecture) 6. From technology black-box to economics of S&T to priority setting to science policy prescriptions – an evolutionary account of knowledge and economic growth (1 Lecture) 7. Evolutionary/Institutional economics – theoretical foundation of innovation systems (1 Lecture) Final Draft

8. Macro-economics of technological change – Processes of technological and institutional innovation; structural and functional changes in components of the innovation system (1 Lecture) o Tutorial – students explore 3 cases of developed vs. developing countries- discuss specific macro-economic and technological change processes, identify institutional and policy changes in the cases 9. State and markets – Innovation trajectories and options from history (1 Lecture) 10. Investing in and planning for S&T – industrial, agricultural and service sector innovation systems (1 Lecture) 11. India’s development experience through an innovation systems lens: a vicious circle of poverty and impeded innovation (1 Lecture) 12. Institutional setting – laying the ground rules - Mahalanobis-Nehru, Pitroda-Gandhi, and the Dhawans, Sivaramans, Pothens and Kalams (1 Lecture) 13. Socio-technological paradigms and paradigm shifters. Climate change vs. the MDGs (1 Lecture) 14. Re-cap + India’s policies and investments in technology generation and extension – for major development sectors (1 Lecture) 15. Current development crisis – the digital divide, risk perceptions and occurrence, GM crops, low cost vaccines/health care, small firms vs. Multinationals (1 Lecture) 16. Eco-friendly and gender sensitive innovation systems for sustainable development; India’s future (1 Lecture) Suggested Reading 1. Veblen, T. The place of science in modern civilization 2. Jacques, E. 1980. “Introduction: Technology and Society” in The Technological System, Continuum: New York 3. Bijker, W. E., Hughes, T. P. And Pinch, T. J. (ed.) 1989. The social construction of Technological Systems: New directions in the sociology and history of technology, MIT Press: Cambridge. 4. Lundvall, B-A, 1992 (ed) National Systems of innovation: Towards a Theory of Innovation and Interactive Learning, Pinter: London 5. Kjell, Rubenson and Shuetze , H. (Ed.s) Transition to the Knowledge Society. 6. Nelson, R. R. 1993. National Innovation Systems: A Comparative Study, OUP: Oxford. 7. Edquist, C. 1997. Systems of Innovation – Technologies, Institutions and Orgnizations, Pinter: London. 8. Freeman, C. 1987. Technology and economic performance: lessons from Japan, Pinter: London. 9. North, D. C. 1990. Institutions Institutional Change and Econ Performance, Cambridge Unv Press: Cambridge. 10. Von Hippel, E. 1995. The sources of Innovation, OUP: New York. 11. Schumpeter, J. 1975. Capitalism, Socialism an Democracy, Harper: new York. 12. Raina, D. And Habib, I. 2008. Domesticating Modern science, Tulika, New Delhi 13. Feenberg, A. 1999. Questioning Technology, Routledge, London. 14. Feenberg, A. 1991. Critical theory of technology, Oxford Univ Press: New York, London. 15. Jasanoff, Sheila et al. (eds.) 1995. Handbook of Science and Technology Studies, Sage: London Final Draft

16. Latour, Bruno 1991. “Technology is Society Made Durable”, in John Law (ed). A 17. Sociology of Monsters, Routledge, London, pp. 103-31 18. Wajcman, J. 2004. Technofeminism, Polity Press: Cambridge, Oxford. 19. Longino, H. 2002. The Fate of Knowledge: Princeton: Princeton University Press.

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Core Course - 5 Course Title: Introduction to History of Science Coordinator: Dr. Satpal Sangwan Lecture-Tutorial-Practical-Credit: 1-2-0-3 Objectives The course in history of science provides interdisciplinary training to research students, policy planners and science administrators for a research career or in the executive wing of state administration. It will introduce students to the principles and methods of interdisciplinary research for understanding the evolution of science as a knowledge system and state apparatus from the ancient times. It will help students to understand and appreciate the social stimulus/constraints on science, social functions of science, and the impact of science on society and economy. Topics and sub-topics The course in history of science will consist of the following thematic topics: 1. Science & Technology in the Ancient World 2. Science & Technology in Pre-Colonial India 3. Rise of Modern Science & Western Colonial Expansion 4. Colonial Science: Methods and Processes 5. Scientific Institutions and Scientific Community 6. Science Education and Research The course will be a mixture of lectures, followed by guided reading, discussion and debate in the seminar sessions. In the first year of the course, students will be taught the basic theoretical and thematic subject issues. The method of delivery will be term papers, group discussion, seminar presentation and dissertation. Suggested Readings 1. Adas, Michael. Machines as the Measure of Men: Science, Technology, and Ideologies of Western Dominance, Ithaca, 1989. 2. Basalla, George. `The Spread of Western Science', Science, 156, May 1967, pp. 611-622. 3. Bose, D.M., S.N. Sen and B.V. Subbarayappa, eds. A Concise History of Science in India, Delhi: INSA, 1971. 4. Chakrabarti, Pratik, Western Science in Modern India: Metropolitan Methods, Colonial Practices, Delhi: Permanent Black, 2004. 5. Cohn, Bernard. Colonialism and its Forms of Knowledge: The British in India, Princeton: Princeton University Press, 1996. 6. Ferguson, Niall. Civilization: The West and the Rest, London: Allen Lane, 2011. 7. Harrison, Mark. Climates and Constitutions: Health, Race, Environment and British Imperialism in India 1600-1850, Oxford: Oxford University Press, 1999. 8. Headrick, D.R. The Tentacles of Progress: Technology Transfer in the Age of Imperialism, 1850-1940, Oxford, 1988. 9. Hull, David L. Science as a Process: An Evolutionary Account of the Social and Conceptual Development of Science, Chicago: University of Chicago Press, 1988. 10. Kuhn, T.S. The Structure of Scientific Revolutions, Chicago: Uni. of Chicago Press, 1970. Final Draft

11. Kumar, Deepak. Science and the Raj, 1857-1905, Delhi: OUP, 1994. 12. Lourdusamy, J. Science and National Consciousness in Bengal, 1870-1930, Delhi: Orient Longman, 2004. 13. Russell, Colon. Science and Social Change 1700-1900, London, 1983. 14. Sardar, Ziauddin. Explorations in Islamic Science, London: Mansell, 1989.

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Core Course - 6 Course Title: Science & Technology Policy Coordinator: Sujit Bhattacharya Lecture-Tutorial- Practical-Credit: 2-1-0-3 Total Teaching Hour: 50 Objective: The course intends to reach out to students with diverse background with the intention of exposing them to the issues that drive formulation of science and technology policy. It exposes students to the various socio-political-economic dimensions of S&T, complex inter-relationships between ‘science and technology’, ‘science and society/economy’, S&T and technological innovation and entrepreneurship’ and evolution/dynamics of these relationships. To what extent these relationships have been affected by endogenous and exogenous actions such as the change in the institution of the scientific enterprise, new demands by the government/industry and the lay public, government and business enterprises involvement in defining the science and technology agenda, competition policy, intellectual property rights, environmental concerns, access and affordability of medicines, poverty, sustainable development will be examined through debates and discourse. The course will expose the students to the international perspective but its main focus will be in the context of India and the developing countries. Topics &Subtopics: 1. Introduction  Knowledge, Invention, Innovation and Entrepreneurship- conceptual issues  Science its Theories and Methods  Facets of knowledge creation and transmission  The evolving relationship between Science & Technology  Big Science and Large Technological Systems- their dynamics and institutional arrangements  Science and Society- Engagements  Technological innovation and entrepreneurship 2. The Past and the Present of Science Policy  The origin of Science Policy: Emergence, historical trend and rationality  Science policy and the Neo Schumpeterian tradition  New Science Policy Agenda- Intellectual origin and challenges  Integrating Innovation and Entrepreneurship in S&T policy framework  Integrating inclusiveness and sustainable development in S&T policy framework  Science policy and S&T Governance 3. Science and Technology Policy in India  Historical evolution of S&T policy  Evolution of Science Policy bodies in India  S&T in parliament, State S&T councils  Funding, Human resource  Competition Policy, regulatory structure, IPR, Trade, etc and its role in science & technology policy formulation Final Draft

  

Country strategy and policy formulation Addressing Innovation and Sustainable development Concerns and mismatches- policy framework and socio-economic deliverance

Suggested Readings 1. Bandelj, N. (2011). The cultural wealth of nations. Stanford, California: Stanford University Press. 2. Bernal, J. D. (1962). Science for a developing world. London: World Federation of Scientific Workers. 3. Chesbrough, H. W. (2006). Open innovation: researching a new paradigm. Oxford: Oxford University Press. 4. Collins, H. M., & Pinch, T. J. (1998). The golem: what you should know about science (2nd ed.). Cambridge : Cambridge University Press. 5. Fagerberg, J. (2005). The Oxford handbook of innovation. Oxford: Oxford University Press. 6. Jasanoff, S. (1995). Handbook of science and technology studies. Thousand Oaks, Calif.: Sage Publications. 7. Jasanoff, S. (1997). Comparative science and technology policy. Cheltenham. Elgar Pub.. 8. Kenney, M. (2000). Understanding Silicon Valley: the anatomy of an entrepreneurial region. Stanford, Calif.: Stanford University Press. 9. MacKenzie, D. A., & Wajcman, J. (1999). The social shaping of technology. Buckingham: Open University Press. 10. MacLeod, C. (1988). Inventing the Industrial Revolution: the English patent system, 16601800. Cambridge: Cambridge University Press. 11. May, C., & Sell, S. K. (2006). Intellectual property rights: a critical history. Boulder, Colo.: Lynne Rienner Publishers. 12. Nowotny, H. (2005). The public nature of science under assault politics, markets, science and the law. Berlin: Springer. 13. Price, D. J. (1963). Little science, big science. New York: Columbia University Press. 14. Porter, M. E. (1998). Competitive advantage: creating and sustaining superior performance : with a new introduction. London: Macmillan. 15. Rosenberg, N. (1982). Inside the black box: technology and economics. Cambridge: Cambridge University Press. 16. Schroeder, R. (2007). Rethinking science, technology, and social change. Stanford, Calif.: Stanford University Press. 17. Schumpeter, J. A. (2011). The entrepreneur: classic texts by Joseph A. Schumpeter. Stanford, California: Stanford University Press. 18. Snow, C. P. (1993). The two cultures (Canto ed.). London: Cambridge University Press. 19. Stokes, D. E. (1997). Pasteur's quadrant: basic science and technological innovation. Washington, D.C.: Brookings Institution Press. 20. Visvanathan, S. (1997). A carnival for science: essays on science, technology, and development. Delhi: Oxford University Press. 21. Wagner, C. S. (2008). The new invisible college: science for development. Washington, D.C.: Brookings Institution Press. 22. Walz, R., et, al. (2008). Research and technology competence for a sustainable development in the BRICS countries. Stuttgart: Fraunhofer-IRB-Verl.. Final Draft

Core Course - 7

Course Title: Science and Technology Systems - India and the World Coordinators : Dr.Tabassum Jamal & Dr. Subhan Khan Lectures-Tutorial-Practical-Credit: 1-2-0-3 Total Teaching hours: 40 Objective: The course in “Science and Technology Systems in India visa-vis world” provides interdisciplinary training to research students, policy planners and science administrators for a research career . It will introduce students to the dynamics and understanding for evolution of S&T systems for economic development and poverty alleviation in India and across the world. The course will help students to look into historical glimpses on advancements of scientific and technological knowledge which made possible the significant reduction of poverty and improvements in the quality of life in both developed and developing countries throughout the 20th century which further helps the students to understand the close link between economic growth and the strategic approaches of S&T system/policies. The course will focus on the S&T system of India which besides the core S&T milieu embraces large number of economic sectors as well as social dimensions. The course will provide the scope to study and analyze the following: (1) social and economic development through progress and applications of S&T; (2) management of S&T infrastructure (3) governance of S&T system (4) modes of funding Topics and Subtopics 1. Science and Technology Policies- Comparative Study/analysis 2. India's Science and Technology Policy and its influence on technology development (Historical perspective of India's Science and Technology Policy) 3. S&T infrastructure and management of development and allocations of developmental Plan funds to involve S&T and hence management of S&T spills over to sectors/ministries for whom S&T is not the core function 4. Evolution of sectoral policies (e.g. Human resource, health, environment, emerging technologies etc) Suggested Readings 1. Science and Innovation Rethinking the Rationales for Funding and Governance, Edited by Aldo Geuna, Ammon J. Salter and W.Edward Steinmueller 2. Science Vol 237 No 4819, 1987 “Science and Technology policies: A comparative analyses” Leonard L. Lederman 3. Government, Innovation and Technology Policy by Sunil Mani 4. Scientific Policy Resolution, Technology Policy Statement (1983) and Science and Technology Policy (2003). 5. The strategic management of Innovation: A sociological and Economic Theory by Jon Sundho

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Elective Course - 1 Course Title: Trade and Technology Coordinators: Dr. Sanjib Pohit and Dr Pradip Kumar biswas Lecture-Tutorial- Practical-Credit: 1-1-0-2 Total Teaching Hour: 30 Objective: This course plans to make students aware of the theories and polices that has led to the globalization of the world economy. The course has three main components namely, international trade, foreign direct investment and international technology transfer. The emphasis on each component is to analyze the channels that are the driving force behind globalization of an economy Topics & Subtopics: 1. International Trade  The underlying causes of foreign trade  Brief review of trade theories and trade policies  Trade restriction and its instruments  The roles of trade in fostering economic development  Foreign trade and trade policies in India  Rationale of the changes in policies since independence  Key emerging issues 2. Foreign Direct investment  Why do firms internationalize  Reasons for international factor movement  Brief review theories of FDI  Potential benefits and costs of FDI for a host country  The roles of FDI in economic development  FDI inflows in India and the policy frame  Characteristics of FDI in flows in India 3. International technology transfer  Types of technology and knowledge transfer  General channels for technology transfer and their influences on production  Brief review approaches of international technology transfer  International operation of national firms (transferability of comparative and competitive advantage)  Conditions of host and home countries for technology transfer  Theoretical implication of international technology transfer  Technology transfer in India  Technology spillover & Intellectual property right protection in India  Technology development in India Suggested Readings 1. Appleyard, D.R., Field, J.R., Alfred, J., & Cobb, S.L., 2008. International Economics.. McGraw-Hill. Final Draft

2. Dunning, John H. & Lundan, S.M., 2008. Multinational Enterprises and the Global Economy. Cheltenham, Northampton: Edward Elgar. 3. United Nations 2008. World Investment Report: Transnational Corporations and infrastructure challenge 2008. United Nation. 4. Krugman, P. and Obstfeld. 2009. International Economics: Theory and Policy, Pearson. Useful Websites: 1. WTO, http://www.wto.org 2. UNCTAD, http://www.unctad.org 3. The World Bank, http://www.worldbank.org 4. Alan Deardorff’s Glossary of International personal.umich.edu/~alandear/glossary

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Economics

Terms,

http://www-

Elective Course - 2 Course Title: Enterprise Development through Value Chains Analysis Coordinators: Dr M. Rais Lecture-Tutorial- Practical-Credit: 2-0-2-4 Total Teaching Hour: 64 (lecture - 32 hours, lab - 32 hours) Objective: To train development professionals in order to increase the impact, scale and sustainability of initiatives that help small enterprises (SEs) grow, create jobs and reduce poverty. Value Chain Analysis enables us to understand competitive challenges and to identify vertical coordination mechanisms. Value Chain Development aims to improve access to markets and increase productive efficiency, ensuring that all actors including the resource-poor, benefit from these value chains. Topics & Subtopics: 1. Value Chains: Introduction     

Introducing the value chain approach Identify and scan sub sectors Develop and apply selection criteria Developing maps to visualise the analyses Determine and measure dimensions of interest

2. Analysis of value Chains     

Undertaking economic analyses of value chains Define critical success factors for value chains and actors Upgrade strategic options and combinations Development models and accompanying roles of stakeholders Guest speaker: practices from the field

3. Application of Value Chains      

Facilitate value chain development process Financial instruments the financial institutions Applying tools in your real life case Applying tools in real life case Presenting and discussing the results of the real life case Planning next step in developing value chains

4. Value Chain Examples from Field   

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Analysis of own value chain – which costs are related to every single activity Analysis of customers value chains – how does our product fit into their value chain Identification of potential cost advantages in comparison with competitors



Identification of potential value added for the customer – how can our product add value to the customers value chain (e.g. lower costs or higher performance) – where does the customer see such potential

Suggested Readings 1. Kaplinsky, Raphael and Morris, Mike (2000) A handbook for value chain research (IDRC). 2. Schmitz, Hubert (2006). Value chain analysis for policy makers and practitioners. 3. Michael E. (1985) Competitive Advantage: Creating and sustaining superior Performance.

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Elective Course - 3 Course Title: Intellectual Property Rights in the Context of Research, Innovation and Development Coordinator: Sujit Bhattacharya Lecture-Tutorial- Practical-Credit: 2-1-0-3 Total Teaching Hour: 50 Objective: The students would be able to learn the nuances of various forms of Intellectual property and their effectiveness in protecting various forms of creativity. They will be exposed to intellectual property innovation and development nexus and conflicts of interest that emerge and how IPR management can be undertaken effectively. Topics and Subtopics: 1. Knowledge, Innovation and Intellectual Property Rights: An Introduction 2. Evolution of IP Statutes – Origin and Internationalisation 3. Contemporary IP Statues: Unification of IP rights 4. IPR and New Technologies 5. IPR in India 6. Debates on IPR and Development Suggested Readings 1. Smith, G and Parr, R.L (1989) Valuation of Intangible Assets. New York: John Wiley & Sons Inc. 2. Cottier, Thomas and Mavroidis, C. Petros (2003). Intellectual Property: Trade, Competition, and Sustainable Development. World Trade Forum, Volume 3. The University of Michigan Press. 3. Berman, Bruce and Woods, D. James (2002). From Ideas to Assets- Investing Wisely in Intellectual Property. Willy Intellectual Property Series. New York: John Wiley & Sons Inc. 4. Background Discussion Papers and Occasional Papers by Quaker United Nations Office Geneva. 5. Commission on Intellectaul Property Rights, Innovation and Public Health (CIPH): Publications and Study Materails (http://www.who.int/intellectualproperty/en/) 6. Intellectual Propert Management in Health and Agricultural Innovation- a handbook of best practices. (www.ipHandbook.org)

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Elective Course - 4 Title: Environmental History Coordinator: Dr. Satpal Sangwan Lecture-Tutorial-Practical-Credit: 1-2-0-3 Objectives The dual course in environmental history will introduce students to the principles and methods of interdisciplinary research for understanding the ever-evolving convergence of science, society and environment. While the course will help students to understand and analyze changing human use/abuse of natural resources on the one hand and also to examine the human understanding and appreciation of the dynamics of natural systems. The main focus will be on the role of culture, ethics, social demands, economy and technology on resource use patterns at different intervals of human history. Topics and Sub-Topics 1. Society and Environment in the Ancient World 2. Collapse of Civilizations : Environmental Causes 3. Colonialism, Capitalism and Environment 4. Global Warming: Myth or Reality 5. Environmental Movements 6. International Environmental Negotiations/Agreements. The course will be a mixture of lectures, followed by guided reading, discussion and debate in the seminar sessions. In the first year of the course, students will be taught the basic theoretical and thematic subject issues. The method of delivery will be term papers, group discussion, seminar presentation and dissertation. Suggested Readings 1. Arnold, David and R. Guha eds., Nature, Culture and Imperialism: Essays on the Environmental History of South Asia, Delhi: Oxford University Press, 1994. 2. Chew, Sing C., World Ecological Degradation: Accumulation, Urbanisation, and Deforestation 3000 B.C-A.D. 2000, California Altamira: Walnut Creek, 2001. 3. Crosby, Alfred W., Jr., Ecological Imperialism: The Biological Expansion of Europe, 9001900, Cambridge: Cambridge University Press, 1986. 4. Diamond, Jared, Collapse: How Societies Choose to Fail or Survive, Penguin Books, 2011 5. Fagan, Brian, The Long Summer: How Climate Changed Civilization, London: Granta Books, 2004. 6. Fleming, Thomas Rodger, Historical Perspectives on Climate Change, NY: Oxford University Press, 1998. 7. Gadgil, Madhav and Ramchandra Guha eds., This Fissured Land: An Ecological History of India, Delhi: Oxford University Press, 1992. 8. Gadgil, Madhav and Ramchandra Guha, Ecology and Equity: The Use and Abuse of Nature in Contemporary India, London: Routledge, 1995. 9. Grove, Richard, Vinita Damodaran and Satpal Sangwan eds., Nature and the Orient: The Environmental History of South and Southeast Asia, eds., Delhi: Oxford University Press, 1998. 10. Hughes, J.D., Ecology in Ancient Civilizations, Albuquerque: University of New Mexico Press, 1975. Final Draft

11. Hughes, D., Pan’s Travail: Environmental Problems of the Ancient Greeks and Roman, Baltimore: John Hopkinns University Press, 1994. 12. Lamb, H., Climate: Present, Past and Future, 2 vols., London: Methuen, 1977. 13. Lawson, Nigel, An Appeal to Reason: A Cool Look at Global Warming, Harper Collins, 2009. 14. Ponting, C., A Green History of the World: The Environment and the Collapse of Great Civilizations, New York: Penguin Books, 1993. 15. Richards, J.F., The Unending Frontiers: An Environmental History of the Early Modern World, Berkeley: University of California Press, 2003. 16. Sen, Geeti, (ed.), Indigenous Vision: Peoples of India’s Attitudes to the Environment, Delhi: Sage Publications, 1992. 17. Shiva, Vandana, Ecology and the Politics of Survival: Conflicts over Natural Resources in India, Delhi: Sage Publications, 1991. 18. Weart, S.R. The Discovery of Global Warming: New Histories of Science, Technology and Medicine, Massachusetts: Harvard University Press, 2003. 19. Williams, M., Deforesting the Earth: From Pre-history to Global Crisis, Chicago: University of Chicago Press, 2003. Worster, Donald (ed.), The Ends of the Earth: Perspectives on Modern Environmental History, Cambridge: Cambridge University Press, 1988.

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Elective Course - 5 Course Title: Resource Planning & Policy Coordinators: Tabassum Jamal, Kasturi Mandal, Subhan Khan, M. Rais Lecture-Tutorial- Practical-Credit: 1-1-1-3 Total Teaching Hour: 40 Objective: The course will have an inquiry driven approach to examine the formulation of resource planning and policy based on theoretical exposition in the domain of macroeconomics particularly the post Keynesian school in economics by addressing the core issues such as, the strength of communities and nations is primarily determined by two aspects, viz.  the availability of resources they have and,(ii) the capacity they have to utilize these in a rational manner.  Those communities and nations have been less developed which could not sufficiently develop the capability to exploit their resources rationally and also those whose resources are over exploited by others.  For developing capabilities, making use of resources and evolving institutional framework for enough utilization of their resources, importance of planning & policy making of resources become much important. Topics and Subtopics: 1. Historical Context of Resources Evaluation 2. Regional Development 3. Resources Utilization in Marginal Areas/stressed lands 4. Resources &Environment 5. Natural & Human Resources Interaction 6. Resources & Poverty Alleviation 7. Geospatial technology applications in resources assessment and planning Suggested Readings Websites 1. www.ask.com/Planning+Resources 2. ibrary.columbia.edu/indiv/avery/guides/urban_planning.print.html 3. www.ifc.org/ifcext/enviro.nsf/.../p.../ResettlementHandbook.PDF 4. store.bizmanualz.com/Human-Resources-Policies-and.../abr41m.htm 5. www.w3.org/WAI/intro/accessibility.php Books 1. Chatterji, Manas, Peter Niojkamp, T.R. Lakshmanan & C.R. Pathak. Spatial, Environmental and Resource Policy in the Developing Countries, published by Gower 2. Handbook for Preparing a Resettlement Action Plan 3. The Policy Process - ODI Working Papers 118 - Working paper 4. Basic Description of Strategic Planning (including key terms to know) Final Draft

5. 6. 7. 8.

Foundations of Real-Time Computing: Scheduling and Resource Management Resource Management In Real-Time Systems And Networks Water Resource Policy Locked Horns: Conflicts and their Resolution in Community Based Natural Resource Management 9. Mineral Resources and Policy in India 10. Forest Resource Policy 11. Human Resource Policy: Concepts, Processes And Applications 12. Renewable Resource Policy: The Legal-Institutional Foundations 13. Environmental and Resource Policy for Consumer Durables 14. Distributional Conflicts in Environmental-Resource Policy 15. Regional Perspectives on Resource Policy: Implementing. 16. Policy Instruments for Environmental and Natural Resource.

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URDIP Ph.D. students will be admitted into Ph.D. (Science) at the moment. The academic credit requirement of the students (total of 20 credits) is made up of three components as explained below. 1. Common Core Credits (8 credits) Every PhD student, irrespective of his/her background and the programme of study, has to fulfill the following requirements (a) MIS( URDIP)-401:0-1-6-4: Project proposal writing Two subject proposals to be prepared before comprehensive examination by selecting topics of high relevance and novelty, and will have state-of-the art review, methodologies, recommendations etc. (2 credits each) Activity Coordinator: PhD Guide (b) MIS(URDIP)-402:0-0-8-4: CSIR-800 Societal Programme The students have to undertake a project in rural area for 6-8 weeks in line with CSIR-800 programme which is primarily prepared at empowering 800 million Indians by way of S & T inventions. Alternatively students admitted at URDIP will be permitted to undertake one of following activities: (i) Create a database of patents which have come into public domain (Expired Patents, Nonjurisdiction Patents, Patents not granted, abandoned applications and Invalid Patents). This database then can be used to Support CSIR-800 programme to solve societal problems quickly. Similar database can also be used to support MSME sector as most of them use old techniques of production and outdated machinery and equipment. The priority will be the areas already identified and referred by the Coordinator of CSIR-800 programme or the laboratories involved in CSIR-800 programme. Based on the identified areas and needs, student will build a problem/subject specific database and share it with scientists/technologists working on the particular project. Alternatively, problem will be chosen from one of the clusters identified under the CSIR Industrial Innovation Cluster programme. (ii) An opportunity assessment study or a techno-economic survey based on a rural resource or for a product or a service that will benefit rural economy. Students will choose the topics in consultation with Doctoral Advisory Committee (DAC). Activity Coordinator: Mr.P.M.Malwadkar 2. Programme Core (6 credits) (a) MIS(URDIP)- 101:1-1-0-2: Research Methodology * Course description: Introduction, Research terminology and scientific methods, different types and styles of research, role of serendipity, creativity and innovation, Scientific and critical reasoning skills, art of reading and understanding scientific papers, literature survey. Final Draft

Measurements in research - primary and secondary data. Quantitative methods and data analysis, Qualitative analysis, Communicating research results. Designing and implementing a research project. Ethics in research, Plagiarism, Case studies. Laboratory safety issues – lab, workshop, electrical, health & fire safety, safe disposal of hazardous materials. Role & importance of communication, Effective oral and written communication. Technical report writing, Technical/R&D proposals, Research paper writing, Dissertation/Thesis writing, Letter writing and official correspondence. Oral communication in meetings, seminars, group discussions; Use of modern aids; Making technical presentations. Course Coordinator: Dr P Goswami *This course will be the one already designed by CMMACS and designated as MIS(CMMACS)-101 or the one to be designed by NISTADS and named as Research Methodology-II ( Qualitative and Critical Studies). (b) MIS(URDIP)- 301:0-2-4-4: Advanced Self Study Aims to train the student on learning, on one's own, topics that are not formally taught in a course. This would involve primarily three components - collection of relevant literature on a chosen topic, organization of relevant material into a written report based on candidate's own critical understanding and finally presentation of the findings in front of wide audience in the form of a seminar. Thus communication skills are also expected to be honed up (4 credits) Course Coordinator: PhD Guide In lieu of Advanced Self Study, students will be free to choose from any of the core courses offered by any of the laboratory in the MIS cluster/ under MIS faculty in consultation with Doctoral Advisory Committee. 3. Programme Electives (6 credits) Any of the following courses may be chosen appropriately to fulfill the total credit requirements. S. No.

Course No.

Course Title

L-T-P-C2

1

MIS(URDIP)-381

IP Management

2-1-0-4

2

MIS(URDIP)-382

R&D Management

2-1-0-4

3

MIS( URDIP)-383

Technology Management

2-1-0-4

4

MIS(URDIP)-384

Patinformatics

1-0-2-2

5

MIS(URDIP)-385

Cheminformatics

2-0-2-3

6

MIS(URDIP)-386

Bioinformatics

2-0-2-3

In addition to above, students will be free to choose from any of the core and optional courses offered by any of the laboratories under AcSIR relevant to topic of their thesis in consultation with Doctoral Advisory Committee. 2

Lecture-Tutorial-Practice-Credits

Final Draft

DETAILS OF ELECTIVE COURSES 1. MIS(URDIP)-381: 2-1-0-3: IP Management Historical overview of IP systems The patent power - What is a patent – Types of patents – Why patent ? – How does the patent system work? Types of applications –Common myths about patents (duration, ownership, freedom to practice, secrecy, global patent, geographical boundaries) – Infringement – Damage awards - Industry structure and importance of patent – Leveraging patents as financial assets – Perils of ignoring patents – IP savvy organizations Requirement of a patent – Criteria for patenting – subject matter, novelty, non obviousness, utility – Enablement, Best mode, Definiteness- Unity of inventions- Inventorship - Statutes – Interpretation – Infringement-Case studies Abstract – Specification – Written description – Claims – Independent and dependent claims – Swiss claims – Length of a document – Claim drafting with file estoppel in mind – Capturing invention Should a patent be filed ? – Where to file – Criteria – When to file? - Timing and filing – Foreign filings – The PCT route – Drafting the application – USPTO procedures – Manipulating patent filing and prosecution process – Maintaining secrecy for longer - Fighting competition – Importance of record keeping. Goals of patent strategy – types of strategies – Shield and sword patents – Protecting markets, Company and future – Protecting single invention – Multiple inventions – Bracketing, clustering and fencing - Strategy for existing products – Patent investment strategies for commercializing technology - Aligning patent strategy with business strategy – Business driven patenting strategy extending the life of invention – Transferring IP assets to business assets – Invention, product and market considerations – Market economies and technology density considerations – Organizing patent portfolio – Enhancing patent quality – Patent cost management – Benchmarking patent strategy against competition – Patent strategy for long term growth – Patent strategy for building corporate assets and exploiting the same – Case studies Conventional flow path for product development – Gaps analysis for R&D planning – New model – From pure research to commercial development – Market pull vs research push Role of IP in M&A decisions –– IP due diligence for M&A – Negotiating value – Case studies Approaches to exploiting IP –When licensing is the preferred option – Rationale for licensing – Objectives of licensing – Carrot and stick licensing, - Licensing decision – factors governing licensing and financial compensation – Approaches to IP valuations – Sharing profits – Cost based valuations – Market based valuations- Industry standards -Researching the markets and targets – Scope of licensing – Exclusive/ non exclusive, territories, duration, non competitive clauses – sublicensing – improvements – cross licensing, - Preparing for negotiations – Steps and processes for negotiation – Responsibilities of the licensor and licensee – Draft agreements – Typical drafts – Licensing as a business strategy in chemical industry – Licensing practices at leading companies - Trends in IP and licensing management – Case studies Final Draft

Levels of IP exploitation in organization – moving up the value chain - organization – From filing to transacting – Transformation at Xerox, Dow Chemicals, P&G (Course Coordinator-Dr.M.G.Kulkarni)

Suggested reading 1. Rivette,K.G. - Rembrandts in the attic: unlocking the hidden value of Patents –-Boston: Harvard Business School Press, 2000 2. Knight,H.J. - Patent strategy: for researchers and research managers -Chichester: John Wiley and Sons, 2001 3. Goldstein,A.N._Ed. - Patent law for scientists and engineers - Boca Raton: Tayolr and Francis, 2005 4. Junghans, C. - Intellectual property management: a guide for scientists, engineers, financers and managers - Weinheim: Wiley Vch, 2006 5. Miller, C.P. - Chemist's companion guide to patent law - Hoboken: John Wiley & Sons, 2010 6. Alexander I. Poltorak, Paul J. Lerner - Essentials of Intellectual Property - John Wiley & Sons, Inc. 2002 - ISBN: 9780471209423 7. Prabuddha Ganguli - Gearing up for patents: The Indian scenario - Universities Press (India) Limited 1998 - ISBN: 8173711054 8. Claas Junghans, Adam Levy - Intellectual property management: A Guide for Scientists, Engineers, Financiers and Managers - Wiley-VCH Verlag GmbH & Co. KGaA, 2006 - ISBN: 9783527312863

Final Draft

2. MIS(URDIP)-382: 2-1-0-3: R&D Management Conceptual framework of R&D management – Origins of industrial R&D – The industrial R&D process - Changing role of R&D in industry - Role of R&D in technological innovation Implications for R&D strategy – Formulating R&D strategy – Evolution of corporate R&D – Centralized vs decentralized R&D – Organizational structure for R&D - Input and output oriented structures – Critical activities of R&D function - Role of leadership - Components of R&D organization – Make vs buy decision - R&D project management - R&D project portfolio Resource allocation for R&D – Managing value and risk in R&D portfolio Aligning R&D portfolio with business strategy - Planning directed basic research - Globalization of R&DImplications for corporate R&D - Coordinating multi locational R&D Location strategies – Global R&D centres in India - From first to fourth generation R&D - Project selection and evaluation - Evaluation of R&D performance – R&D performance metrics – R&D performance effectiveness and impact - Decision support systems for R&D project management – Terminating R&D projects - Post project evaluation and learning - Trends in R&D management – Open Innovation- Working with national innovation systems – Directed basic research with universities - Managing R&D collaborations – Issues in value based R&D Case studies in R&D management - 3M, DuPont, GE, P&G , Merck. (Course Coordinators: Dr.M.G.Kulkarni/Dr.R.R.Hirwani)

Suggested reading 1 2 3

Saunders, J.H. - Careers in industrial research and development - 1974 White,P.A.F. - Effective management of research and development , 1975 Rawat, A. - Management of corporate R & D and innovation - Global Business Press, Delhi 1995 4 Bamfield,P. - Research and development management in the chemical industry – Vch Verlagsgesellschaft Mbh, Weinheim, 1996 5 Cohan,P.S. - Technology leaders: how america's most profitable high tech companies innovate their way to success - Jossey Bass Inc., San Francisco, 1997 6 Chiesa,V. - R and D strategy and organization: managing technical change in dynamic contexts London: Imperial College Press, 2001 7 Martin, M.J.C. - Managing innovation and entreneurship in technology based firms Wiley Interscience, New Yotk, 1994 8 Miller, W.L. - Fourth generation R and D: managing knowledge, technology and innovation John Wiley And Sons Inc, New York, 1999 9 Reddy,P. - Globalization of corporate R & D: implications for innovation systems in host countries - Routledge, London, 2000 10 Harvard Business School - Harvard business review on managing projects - Harvard Business School Press, Boston, 2005

Final Draft

3. MIS(URDIP)-383: 2-1-0-3: Technology Management Concept and framework of technology management - Strategic role and scope of technology management – Technology life cycles and flow processes- S curves in technological progress – Technology push vs market pull – Product life cycles – Technology diffusion The technology environment – Industry structure – Organizational structure – resources – Competitive advantage at firm and national level Product, technology and business strategy – Aligning strategies The positioning approach – Resource based approach – Rationalist and incrementalist approach Technology selection –Timing – Acquisition or development – Make vs buy decision – Types of technology strategies Models of technology growth and diffusion – Forecasting techniques and tools – Managing forecasting process – case studies from industries – Technology monitoring – Trend analysis techniques and tools – Simulation and scenario building – Economic forecasting and analysis – Forecasting directions and changes – Forecasting technological discontinuities and change Mapping technological environment – competitor activities –assessing technological positions Technology analysis – Technology base of the firm - Technology planning and business strategy - The planning process – Case studies from chemical industries Profit sharing – Cost basis – Market basis – Economic assessment- DCF analysis to estimate present value Modalities of acquisition – Joint ventures – outsourcing - Licensing – Discipline of acquisition – Role of management – Factors influencing managerial decision – selecting partners – Case studies The licensing decision – Licensing strategies – Due diligence prior to licensing - Licensing agreements – Negotiating and drafting – Model agreement- Post licensing activities - Licensing from universities – case studies Technology transfer, Technology management case studies, Developing technology managers. (Course Coordinator-Dr.R.R.Hirwani) Suggested reading 1. 2. 3. 4. 5. 6. 7. 8. 9. 10.

Final Draft

Gaynor,G.H._Ed. - Handbook of technology management - Mc-Graw Hill, New York, 1996 Betz, F - Strategic technology management - Mcgraw-Hill, Inc., New York, 1993 Boer, F.P. - Valuation of technology: business and financial issues in R and D John Wiley and Sons, New York , 1999 Megantz,R.C. - Technology management: developing and implementing effective licensing programs - John Wiley and Sons, New York , 2002 Khalil,T.M. - Management of technology - Mc Graw Hill Book Co, Singapore, 2000 Narayanan,V.K. - Managing technology and innovation for competitive advantage Pearson Education Inc., Delhi, 2001 Szakonyi, R._Ed - Technology management, Auerbach - 1999 Porter, A.L. - Forecasting and management of technology - Wiley Interscience, New York, 1991 Martin, M.J.C - Managing innovation and entreneurship in technology based firms - Wiley Interscience, New York, 1994 Phaal, R., - T plan: the fast start to technology road mapping planning your route to success Institute of Manufacturing, University of Cambridge, Cambridge, 2001

4. MIS(URDIP)-384: 1-0-2-2: Patinformatics Introduction to IPR, Understanding Patents and Patent Legislation – Requirements of Patentability, Patent Treaties, Reading a patent -– Anatomy of a patent and implications - Dissecting the parts – Independent and dependent claims – Claim interpretation – Evaluating strengths and weaknesses of a patent – The file history and implications Introduction to Patinformatics – Patent Families, Patent Citations- Relationships and Trend Analysis- Patent Intelligence – Patent Searching-Types of searches- Patentability – Validity – Infringement – Clearance (FTO)- State of the art – Landscape search –Search methodologies – Key word searches-Patent classification systems, Introduction to patent databases (Free and Paid), Searching on various patent databases, Patent analysis and mapping, Patent analysis and mapping tools, Patent information for strategic planning and technology management, Patent indicators and patent statistics for policy making, Planning R&D investments and measuring R&D performance

Hands-on – Patent searching, Patent search and analysis reports for various end uses. (Course Coordinator- Ms. Rashmi Phadnis)

Suggested reading 1. Adams , Stephen R. - Information Sources in Patents - K G Saur Verlag, 2005, ISBN: 9783598244438 2. Hunt,, David; Nguyen, Long; Rodgers, Matthew - Patent Searching: Tools & Techniques - John Wiley & Sons, Inc., 2007 3. Hitchcock, David - Patent Searching Made Easy : How to Do Patent Searches on the Internet & in the Library - Nolo, 2009, ISBN: 9781413310368 4. Gibbs, Andy; DeMatteis, Bob. - Essentials of Patents - John Wiley & Sons, Inc. 2003, ISBN: 9780471250500

Final Draft

5. MIS(URDIP)-385: 2-0-2-3: Cheminformatics Introduction to cheminformatics: aims, scope- Role of Cheminformatics in pharmaceutical/chemical research- Representation and manipulation of 1D, 2D and 3D molecular structures.-Molecular file formats (SMILES, WLN, SDF, MOL), Molecular patternsSMARTS, SMIRKS- Molecular descriptors - Calculation of descriptors reflecting physical and chemical properties of the molecules, including fingerprints and methods used for evaluation of molecular similarity and for selection of structurally diverse and representative subsets Properties - Calculation of physico-chemical properties such as solubility and partition coefficients, pharmacological properties such as absorption and distribution, and global properties such as oral bioavailability and "drug-likeness" data analysis- Molecular similarity and molecular diversity analysis. Similarity index- Molecular Database Screening: (Lipinski Rule: Drug/Lead like molecules) Clustering and Statistical analysis for Molecular Informatics (PLS, PCA, PCR, kNN, ANN, Correlation and regression analysis)- Modeling of small molecules using molecular mechanics and quantum mechanics methods. Quantitative structure activity relationship (QSAR), Quantitative structural property relationship (QSPARs), Quantitative structural Toxicity Relationship (QSTR), Pharmacophore modeling- In silico virtual screeningDocking studies. (Course Coordinator- Mr.R.C.Dash)

Suggested reading 1.

Leach, Andrew R.; Gillet , Valerie J. - An introduction to Chemoinformatics - Kluwer

2.

Academic Press, 2003. ISBN: 1402013477 Bunin B.A. et al. - Chemoinformatics: Theory, Practice, & Products - Spingerlink, 2007. ISBN 978-1-4020-5000-8

3.

Gasteiger, Johann; Thomas, Engel - Chemoinformatics: A Textbook - Wiley- VCH, 2003. ISBN: 3527306811.

4.

Oprea, Tudor I. - Chemoinformatics in drug discovery - Wiley-VCH, 2005

5.

Ekins, Sean, ed. - Computer Applications in Pharmaceutical Research and Development Wiley, New Jersey, 2006

Final Draft

6. MIS(URDIP)-386: 2-0-2-3: Bioinformatics What is bioinformatics, Basic concepts, Sequence, structure and function, Bioinformatics databases, Type of databases, Secondary nucleotide sequence databases, Sequence motif databases, Protein structure databases, Other relevant databases such as KEGG, DockGround, Sequence alignment and database searching, scoring matrix, Dynamic programming, Heuristic methods, Statistics of sequence alignment score, Multiple sequence alignment, Hidden Markov Models Protein structure alignments, structure superposition, RMSD, Different structure alignment algorithms, Protein secondary structure predictions, Protein tertiary structure modelling, Protein folding and dynamic simulation, Comparative modelling, Threading, Combined modeling approaches, Protein quaternary structure modelling. Rapid development programming languages (Python, Perl), relational databases (SQL), Java, exploratory data analysis in R. Techniques for designing efficient algorithms and basic mathematical methods for analyzing their performance. Paradigms for algorithm design: divide-and-conquer, greedy methods, graph search techniques, dynamic programming. Protein-protein docking algorithms, Semi-flexible docking: Side-chain refinement, Protein-ligand docking algorithms, Multiple-threading algorithms. (Course Coordinator: Mr. Nishad Deshpande)

Suggested reading 1. Mount, David. Bioinformatics: Sequence and Genome Analysis. CSL Press (2004) 87969-687-7

ISBN:0-

2.

Husmeier,, Dirk et al - Probabilistic Modelling in Bioinformatics and Medical Informatics Springer, 2004. ISBN: 1-85233-778-8

3.

Rigden , Daniel - From Protein Structure to Function with Bioinformatics, Springer 2009. ISBN 978-90-481-8058-5

4.

Jenny Gu, Philip E. Bourne. Structural Bioinformatics. Wiley (2009) ISBN-13: 978-0-470-18105-8

5.

Model , Mitchell L. - Bioinformatics Programming Using Python Practical Programming for Biological Data. O'Reilly Media (2009) ISBN-978-0-596-15450-9

6.

Tisdall, James D.- Beginning Perl for Bioinformatics An Introduction to Perl for Biologists O'Reilly Media, 2001 ISBN-978-0-596-00080-6

7.

Bal , Harshawardhan; Hujol, Johnny. - Java for Bioinformatics and Biomedical Applications 2006. ISBN-13: 978-0-387-37237-8

Final Draft

List of Coordinators/Nodal Officers

S No 1 2

Laboratory C-MMACS NAL

Nodal Officer Dr I A Parvez Dr V Mudkavi

E mail [email protected] [email protected]

3

NISCAIR

[email protected]

4

NISTADS

5

URDIP

Dr. Tarakanta Jana Parthasarathi Banerjee Dr Raj Hirwani

Final Draft

Telephone 080-25051357 080-25220952, 25051617

[email protected] [email protected]

020-25383558

Annexure III-E

Course Content of Physical Sciences

Special Meeting of Senate 08.06.2012

Final Draft

AcSIR-Physical Science 1. 2. 3. 4. 5. 6. 7. 8. 9.

Final Draft

CSIR-CEERI CSIR-CMMACS CSIR-CSIO CSIR-IMMT CSIR-NCL CSIR-NEERI CSIR-NGRI CSIR-NIO CSIR-NPL

Ph.D courses in Physical Sciences

Final Draft

For Ph.D (Sciences) a minimum of 20 Credits through course work have to be completed from the following courses (being offered at particular laboratories), out of which a few are mandatory. The courses have to be selected on the recommendations of the doctoral advisory committee (DAC) of the Ph.D. student. Mandatory Courses: Course Code 1. 2. 2. 3.

1-001 3-001 4-001 4-002

Course Name Research Methodology Advanced Self Study CSIR-800 Societal Programme Project Proposal writing (I & II)

Credits 2 4 4 4

4-001 Six of eight weeks have to be dedicated on a project concerned with societal/rural issues under the CSIR-800 Programs (4 Credits). This course will need to be completed during the residency period after the PhD comprehensive examination and before submission of their PhD thesis 4-002 Two subject proposals to be prepared before comprehensive by selecting topics of high relevance and novelty and will have state-of-the-art review, methodologies, recommendations, etc. (2 Credits each). Depending on the academic background of the candidate, proposed area of research, category of PhD programme, and recommendation of the doctoral advisory committee, each PhD candidate will need to complete an appropriate mix of 1-xxx (2-4 credits), 2-xxx (6-8 credits), and 3-xxx (2-4 credits) level courses that meet or exceeds the minimum number of credits requirements.

Final Draft

1. CSIR-CEERI (Central Electronics Engineering Research Institute, Pilani) C. No. PHY(CEERI) :1-001

Course Name

L-T-P-C

Research Methodology

1-1-0-2

PHY(CEERI) : 1-136 Technical Communication

2-0-0-2

PHY(CEERI) :2-136

Project Management

2-0-0-2

PHY(CEERI) :2-141

Physics of Semiconductor Materials and Devices

4-0-0-4

PHY(CEERI) :2-142

Unit Processes in Semiconductor Technologies

3-0-0-3

PHY(CEERI) :2-143

CMOS Digital VLSI Design

3-0-0-3

PHY(CEERI) :2-144

Characterization Techniques for Semiconductor Materials, Technologies and Devices

3-0-0-3

PHY(CEERI) :2-145

Semiconductor Processing Technologies Laboratory

0-0-4-2

PHY(CEERI) :2-146

CMOS-based Physical Design Laboratory

0-0-4-2

PHY(CEERI) :2-147

Semiconductors Related Characterization and Measurement Techniques Laboratory

0-0-4-2

PHY(CEERI) :2-148

HDL-based Digital Design Laboratory

0-0-4-2

PHY(CEERI) :2-151

Electromagnetic Theory and Transmission Lines

4-0-0-4

PHY(CEERI) :2-152

Microwave Communication

2-0-0-2

PHY(CEERI) :2-153

Numerical Techniques and CAD of Microwave Tubes

4-0-0-4

PHY(CEERI) :2-154

Microwave and Millimeter-wave Tube Technologies

3-0-0-3

PHY(CEERI) :2-155

Microwave Components Characterization and Tube Processing Techniques Laboratory

0-0-6-3

PHY(CEERI) :2-156

Microwave Devices Characterization and Tube Sub-assembly Fabrication Laboratory

0-0-6-3

PHY(CEERI) :3-001

Advanced Self-Study (Special Topic)

0-2-4-4

PHY(CEERI) : 3-141 MEMS Technology, LTCC and Packaging

3-0-0-3

PHY(CEERI) :3-142

Physics and Design of MEMS and Microsensors

3-0-0-3

PHY(CEERI) :3-143

Nanoelectronic Devices and Technologies

3-0-0-3

PHY(CEERI) :3-144

Advanced VLSI Technologies and Devices

3-0-0-3

Course Name

L-T-P-C

PHY(CEERI) :3-145

CMOS Analog Design

3-0-0-3

PHY(CEERI) :3-146

Advanced VLSI System Architectures

3-0-0-3

PHY(CEERI) :3-147

Optoelectronic Materials, Devices and Technologies

3-0-0-3

PHY(CEERI) :3-148

Photonic Materials, Devices and Technologies

3-0-0-3

C. No.

Final Draft

PHY(CEERI) :3-151

MEMS Technology, LTCC and Packaging Laboratory

0-0-4-2

PHY(CEERI) :3-152

Design of MEMS and Microsensors Laboratory

0-0-4-2

PHY(CEERI) :3-153

Nanoelectronic Technologies Laboratory

0-0-4-2

PHY(CEERI) :3-154

Study and Seminar on Advanced VLSI Technologies

0-0-4-2

PHY(CEERI) :3-155

CMOS Analog Design Laboratory

0-0-4-2

PHY(CEERI) :3-157

Optoelectronic Devices and Technologies Laboratory

0-0-4-2

PHY(CEERI) :3-158

Photonic Devices and Technologies Laboratory

0-0-4-2

PHY(CEERI) :3-161

Slow-wave Devices : Principles and Design

4-0-0-4

PHY(CEERI) :3-162

Fast-wave Devices : Principles and Design

3-0-0-3

PHY(CEERI) :2-163

CAD of Microwave Tubes Laboratory

0-0-4-2

PHY(CEERI) :3-164

High Power Microwave Devices, Systems and Applications

3-0-0-3

PHY(CEERI) :3-165

Electron Emitters and Surface Characterization

2-0-0-2

PHY(CEERI) : 3-166 Plasma-filled Microwave Sources

2-0-0-2

PHY(CEERI) :3-167

2-0-0-2

Vacuum Microelectronic Devices

PHY(CEERI) : 4-001 CSIR-800 Societal Programme

0-0-8-4

PHY(CEERI) :4-002

0-1-6-4

Final Draft

Project Proposal Writing (I & II)

Brief Description of Physical Science Courses at CSIR-CEERI (Course Level-Wise) PHY(CEERI) : 1-001 : Research Methodology : 1-1-0-2 Course Coordinator : Raj Singh Introduction, terminology, and scientific methods; Types of research; Research process and steps; Identifying a research problem; Literature survey, appreciation of existing literature, identification of knowledge gaps; Conception of novel approach to solve the problem; Role of theory, modeling, and simulation; Design of experiments, testing and characterization strategies; Quantitative methods and data analysis; Qualitative analysis; Communicating research results; Thesis writing and oral presentation; Ethics in research. PHY(CEERI) : 1-136 : Technical Communication : 2-0-0-2 Course Coordinator : Raj Singh Role and importance of technical communication; Effective written and oral communication; Ethical issues; Technical report writing; Technical / R&D proposals; Research paper writing; Letter writing and official correspondence; Emails; Oral communication in meetings and group discussions; Oral presentations; Use of modern aids. PHY(CEERI) : 2-136 : Project Management : 2-0-0-2 Course Coordinator : Raj Singh Introduction; Project formulation, evaluation and initiation; Project planning and scheduling; Risk management; Project execution and implementation; Project monitoring and control; Project closure; Project documentation; Leadership and teamwork issues; Complex projects; Advances and trends. PHY(CEERI) : 2-141 : Physics of Semiconductor Materials and Devices : 4-0-0-4 Course Coordinators : J. Akhtar and S. C. Bose Semiconductors; Inorganic and organic, single crystalline, polycrystalline, porous, amorphous crystal structures, and material properties; Si, GaAs, GaN, SiC; Energy band diagrams; Dielectric constant, permeability, permittivity, sheet resistance, resistivity, mobility, thermal conductivity and heat dissipation; Piezo-resistive and piezo-electric effects; Defects, dislocations and micro-plasma, phonon dynamics, ion-solid interactions; Electron transport in semiconductors, minority carrier life time, avalanche breakdown phenomena, Hall effect; Theory of p-n junction, Schottky barrier, MOSFETs and MESFETs, IMPATTs and BARRITTs; Hetro-structures, strained semiconductors; Photovoltaics and solar cell; Solid state sensors and transducers; MOS analysis. PHY(CEERI) : 2-142 : Unit Processes in Semiconductor Technologies : 3-0-0-3 Course Coordinator : G. Eranna Crystal growth techniques, wafer preparation and shaping, chemical cleaning, thermal oxidation, photo-lithography, chemical etching (wet and dry), chemical vapor Final Draft

deposition techniques, thermal diffusion, ion implantation, metalization, chemical mechanical polishing, rapid thermal processing. PHY(CEERI) : 2-143 : CMOS Digital VLSI Design : 3-0-0-3 Course Coordinator : A. Karmakar Introduction to MOSFET from designer's viewpoint; MOS inverter : static and switching characteristics; MOS capacitor; Layers in VLSI design; Design rules and technology interface; Stick diagrams and Layout design; Propagation delay, Fan-out consideration; CMOS Latch-up; Scaling; Combinational MOS logic circuits : passtransistors/transmission gates, primitive logic gates, complex logic gates; Sequential MOS logic circuits : latches and flip-flops; Dynamic logic circuits; Clocking issues; CMOS subsystem design. PHY(CEERI) : 2-144 : Characterization Techniques for Semiconductor Materials, Technology and Devices : 3-0-0-3 Course Coordinator : K. J. Rangra and G. Eranna Resistivity, Contact resistance, barrier height, carrier and doping concentration, mobility and carrier life time measurement techniques; Test structures for technology characterization; Analysis of surfaces, interfaces, thin films and devices; E-beam based techniques, Scanning Electron Microscopy and allied techniques; Material analysis techniques; Scanning probe Techniques; Ion-beam based techniques; Interferometry based techniques for materials and device characterization; Optical characterization. PHY(CEERI) : 2-145 : Semiconductor Technologies Laboratory : 0-0-4-2 Course Coordinator : G. Eranna Laboratory practices and safety considerations; Wafer preparation and shaping; Chemical cleaning; Thermal oxidation, photo-lithography; Wet chemical etching; Dry etching; Chemical vapor deposition; Thermal diffusion; Ion implantation; Metalization. PHY(CEERI) : 2-146 : CMOS-based Physical Design Laboratory : 0-0-4-2 Course Coordinator : A. Karmakar Laboratory practices and safety considerations; SPICE simulation; Schematic editor, Layout editor, DRC, LVS; Transfer and output characteristics NMOS transistor, parameter variations; CMOS inverter design, inverter threshold, noise margin, propagation delay; Layout of CMOS inverter, n-well design rules, LVS, static and transient characteristics, DRC; 2-input NAND/NOR gate; D latch and flip-flop; Postextract simulation. PHY(CEERI) : 2-147 : Semiconductors Related Measurement Techniques Laboratory : 0-0-4-2 Course Coordinator : K. J. Rangra and G. Eranna

Characterization

and

Laboratory practices and safety considerations; IV and CV Measurements; Resistivity, thickness, thin-film surface and bulk defects; grain size measurement; AFM/STM surface analysis; Stress and deformation measurements; Measurement of Final Draft

sheet resistance, junction depth, carrier mobility, doping profile estimation, minority carrier life-time measurement; Model parameter extraction experiments. PHY(CEERI) : 2-148 : HDL-based Digital Design Laboratory : 0-0-4-2 Course Coordinator : A. S. Mandal Laboratory practices and safety considerations; Introduction to HDLs; Simulation of behavioral, Architecture/RTL, data-flow and structural HDL code; Sub-system design using HDL : various adder architectures, BCD arithmetic, various counters, trafficlight controller, etc.; Mini-project. (SystemC, VHDL and/or SystemVerilog will be used as the HDL for the laboratory.) PHY(CEERI) : 2-151 : Electromagnetic Theory and Transmission Lines : 4-0-0-4 Course Coordinator : A. K. Sinha Maxwell’s equations; Wave equations and their solutions; Boundary Conditions and their applications; Electromagnetic energy and power flow; Poynting theorem. Transmission lines; Wave-guide and coaxial components. Scattering matrix representation; Propagation of electromagnetic waves through homogeneous, inhomogeneous, and anisotropic media. Surface resistance and RF resistance. Ferrite devices. Waveguides and resonators. Characteristic and interaction impedances. Quality factors (loss and diffractive). Impedance Matching. Measurement of “Q”, power, noise figure, S-parameters, dielectric constant and loss tangent, dispersion and impedance characteristics, and loss parameters. PHY(CEERI) : 2-152 : Microwave Communication : 2-0-0-2 Course Coordinator : V. V. P. Singh Ground/surface wave, space-wave, and sky-wave modes of communication; Troposphereic Communication; Line of sight communication and system performance; Active and passive repeaters and their design; Analog and digital communication; Mobile communication; Satellite communication system; Earth station design criteria and direct reception system; Satellite transponders and their design criteria; PhPHY(CEERI)-noise, intra-pulse and inter-pulse noises and their significance. PHY(CEERI) : 2-153 : Numerical Techniques and CAD of Microwave Tubes : 40-0-4 Course Coordinator : V. Srivastava Numerical solution of linear and non-linear differential equations of higher orders; Analytical and numerical techniques to the solution of electromagnetic field problems; Numerical techniques for the electrical, thermal, and structural design of slow-wave and fast-wave microwave tubes; Spent beam analysis for efficiency enhancement; Special focusing techniques for multi-beam electron guns; PIC simulation techniques; Finite difference and finite element techniques; Method of moments applied to microwave devices.

Final Draft

PHY(CEERI): 2-154: Microwave and Millimeter-Wave Tube Technology : 3-0-0-3 Course Coordinator : R. S. Raju Fundamentals of vacuum technology. Vacuum generation and measurement, and leak detection. Ultra-high vacuum techniques. Surface physics and analysis in relation to electron Emitters. Electron-tube grade materials and their characteristics. Chemical processing. Heat treatment and special techniques: brazing, sintering, sputtering, TIG/electron beam/laser welding, glass-to-metal and ceramic-to-metal sealing, loss coating, and helix fitting. Vacuum processing of integrated devices. Design of tools, jigs, and fixtures. Engineering / mechanical design of components. Special machining techniques. PHY(CEERI): 2-155: Microwave Components Characterization and Tube Processing Techniques Laboratory: 0-0-6-3 Course Coordinator: O. S. Lamba Laboratory practices and safety considerations; Scattering parameters; Measurement of impedance and characterization of cavities; Dispersion and impedance characterization of RF structures; RF loss measurements; UHV techniques; Heat treatment in protective atmosphere; Ceramic-to-metal sealing techniques; Chemical processing of components. PHY(CEERI) : 2-156 : Microwave Devices Characterization and Tube Subassembly Fabrication Laboratory : 0-0-6-3 Course Coordinator: L. M. Joshi Laboratory practices and safety considerations; Device characterization using spectrum analyzer, scalar/vector analyzer; Break-down tests; X-ray radiography; Cathode characterization using Auger and Thermal emission microscope; Hot RF characterization of devices; Metal-to-metal brazing techniques; Leak detection; TIG/laser welding; Vacuum processing of devices; Cathode fabrication. PHY(CEERI) : 3-001 : Advanced Self-study (Special Topic) : 0-2-4-4 Course Coordinator: Senior Scientists This will involve readings from published literature or books about new frontiers on a specific topic related to the field of electronics under guidance of senior scientist(s). A report needs to be submitted and a seminar on the special topic needs to be presented. PHY(CEERI) : 3-141 : MEMS Technology, LTCC and Packaging : 3-0-0-3 Course Coordinator: B. D. Pant and P. K. Khanna Review of Silicon crystal and unit processes; Processing steps for MEMS device fabrication; photo-lithography and backside mask alignment; Surface and bulk micromachining techniques; Deep reactive ion etching; LIGA process; Wafer-level bonding and packaging techniques; LTCC technology, materials, LTCC process steps, bonding and packaging; Testing and characterization of technology; Reliability and residual stress issues.

Final Draft

PHY(CEERI) : 3-142 : Physics and Design of MEMS and Microsensors : 3-0-0-3 Course Coordinator : Ram Gopal and K. J. Rangra Overview of Microsensors; Mechanical properties of materials and essentials of structural mechanics; Electro-mechanical, magneto-mechanical and piezo-based sensing; Structural elements for MEMS and microsensors (Beams, plates, cantilevers, bridges and diaphragms); Electrostatic sensing and actuation (parallel plate and torsional structures, time domain analysis); Micro-fluidics; Scaling laws and miniaturization; Micro-system design principles; MEMS simulation and design Tools; RF MEMS; Reliability issues in microsensors; Examples and applications of MEMS microsensors. PHY(CEERI) : 3-143 : Nanoelectronic Devices and Technologies : 3-0-0-3 Course Coordinator : Anil Kumar Low-dimensional structures (Quantum well, quantum wire, quantum dot, quantum confinement); Confinement energy level, band-gap enhancement, absorptionemission spectra, blue shift, luminescence; Nanoelectronic Devices (Single electron box, Coulomb blockade, single electron transistor, pump, turnstile, trap, memory); Simulation, Modeling of single electron devices and applications; Technology for fabrication of nanostructures and nanoelectronic devices; Next generation lithography techniques; Characterization of nanoscale materials and nanodevices. PHY(CEERI) : 3-144 : Advanced VLSI Technologies and Devices : 3-0-0-3 Course Coordinator : G. Eranna and W. R. Taube Overview of VLSI technology; Effect of scaling on MOS devices and interconnections; Hot electron degradations and drain engineering structures; Process and material requirements for VLSI devices; Advanced thin-film deposition and VLSI process techniques; High-k dielectric and low-k dielectric materials; Process integration of high-k metal gate for nanoscale CMOS technology; Device characterization, failure diagnosis and reliability measurements; Carrier transport mechanisms, velocity saturation, ballistic transport; Nanoscale MOSFET, FinFET and Multi-gate FET; Emerging materials and future devices. PHY(CEERI) : 3-145 : CMOS Analog Design : 3-0-0-3 Course Coordinator : S. C. Bose Basic concepts of transistors and diodes, their modeling, large-signal and small signal analysis, CMOS technology, clock feed-through; Reference sources : bias circuits, band-gap reference circuit, cascode current mirror; Single-stage amplifier, common source amplifier, drain and gate amplifier, differential amplifier; Operational amplifier; Comparators; Switched-capacitor circuits; Introduction to data converters; Issues of analog layout and device noise. PHY(CEERI) : 3-146 : Advanced VLSI System Architectures : 3-0-0-3 Course Coordinator : A. S. Mandal Introduction and review of basic computer architectures, CISC and RISC processors; Pipelining, hazards, exception handling, optimization techniques, synchronous and Final Draft

asynchronous pipelining; Memory organization, caches, virtual memory, memory management; Arithmetic circuits, algorithms and architectures for high-radix adders, multipliers, sine-cosine and exponential computation; Instruction-level parallelism, super-scalar, super-pipelined and VLIW architectures, array and vector processors; Multiprocessor architectures and parallel architectures, synchronization, memory consistency; DSP architectures; Performance improvement techniques; ASIP; Lowpower architectures; Fault-tolerant architectures; Case-study on Algorithm-toArchitecture; Future trends. PHY(CEERI) : 3-147: Optoelectronic Materials, Devices and Technologies : 3-00-3 Course Coordinator : C. Dhanvantri Optoelectronic Materials; Growth of Epitaxial materials; Characterization of Epitaxial Materials; Optoelectronic Devices (Light Emitting Diodes, Semiconductor Lasers, UV, Visible and IR Photo-detectors and Receivers, Solar Cells); Compound semiconductors and advanced electronic devices; Compound Semiconductor Technologies; Packaging of compound semiconductor components; Applications and trends. PHY(CEERI) : 3-148 : Photonic Materials, Devices and Technologies : 3-0-0-3 Course Coordinator : S. Pal Introduction to Photonics; Basic photonic components and their technologies; Propagation of Electromagnetic waves; Optical waveguides and optical fibers; Principle of optical fiber communications, Transmission capacity, Dispersion and losses in optical fiber; Coupled mode theory in guided wave systems; Materials and fabrication technologies; Types of waveguides; Basic photonics devices and components; Optical sensors and sensing techniques; Optical MEMS; Fiber gratings and waveguide gratings; Photonic crystal based waveguides and devices; Packaging of photonic devices; Applications of photonic devices; Recent trends. PHY(CEERI) : 3-151 : MEMS Technology, LTCC and Packaging Laboratory : 00-4-2 Course Coordinator : B. D. Pant and P. K. Khanna Laboratory practices and safety considerations;; Wafer cleaning; Lithography : front and backside alignment; Bulk micro-machining; DRIE process; LPCVD; Metalization; Wafer bonding; Surface planarization; Wafer dicing; LTCC process; Packaging. PHY(CEERI) : 3-152 : Design of MEMS and Microsensors Laboratory : 0-0-4-2 Course Coordinator : Ram Gopal and K. J. Rangra Laboratory practices and safety considerations; MEMS design tools; Design of pressure sensors of various types; Design of gas sensors of various types; Acoustic, Ultrasonic, micro-resonator, ISFET; RF MEMS design and simulation. PHY(CEERI) : 3-153 : Nanoelectronic Technologies Laboratory : 0-0-4-2 Course Coordinator : Anil Kumar

Final Draft

Laboratory practices and safety considerations; Fabrication of metal thin films by sputtering/e-beam/resistive-heating and measurement of film thickness by making steps using wet etching; Experiments on growth of Silicon nanoparticles and their optical characterization; Experiments with nanolithography and nanopatterning; Simulation of single electron devices using SIMON; Simulation of inverter circuit using SET in SIMON; Operation of AFM/STM; Analysis of AFM/STM images; Study of annealing effect on roughness/grain size of metal films by AFM/STM imaging and analysis. PHY(CEERI) : 3-154 : Study and Seminar on Advanced VLSI Technologies : 00-4-2 Course Coordinator : G. Eranna and W. R. Taube This will involve literature search, review and study of current research on materials, process methodologies and simulations, and novel applications related to advanced VLSI technologies and nanoelectronics. Simulation studies and experiments may also be carried out, where possible. A study report is to be submitted and a seminar is to be given. PHY(CEERI) : 3-155 : CMOS Analog Design Laboratory : 0-0-4-2 Course Coordinator : S. C. Bose Laboratory practices and safety considerations; I-V characteristics of MOSFET, estimation of early voltage; Clock feed-through and its minimization; Bias generation architecture simulation; Band-gap reference circuit simulation; Design and simulation of various amplifiers; Design and simulation of 2-stage CMOS operational amplifier; Layout of analog circuits. PHY(CEERI):3-157 : Optoelectronic Devices and Technologies Laboratory : 00-4-2 Course Coordinator : C. Dhanvantri Laboratory practices and safety considerations; Lift-off process for Ohmic Contact on GaAs substrate; TLM measurements for specific contact resistance; RIE process for GaAs etching; LI Characteristics of 980 nm Laser Diode; Transistor characteristics of GaAs Power MESFET; LED Characteristics; Photoluminescence characterization of GaN epitaxial material; Characterization of PIN-FET receiver module. PHY(CEERI) : 3-158 : Photonic Devices and Technologies Laboratory : 0-0-4-2 Course Coordinator : S. Pal Laboratory practices and safety considerations; Measurement of refractive index and thickness of planar waveguides; Propagation loss measurement of planar waveguides; Design of 1x2 and 1x4 optical power splitter; Measurement of insertion loss, uniformity and polarization-dependent loss of a packaged 1x8 optical splitter at C+L band region; Design and simulation of Bragg gratings; Waveguide patterning by photo-lithography; Testing of MUX/DEMUX by DWDM test set-up; Chip-level testing: alignment of DUT (in a diced chip) to the source and the detector with x-y-z alignment stages.

Final Draft

PHY(CEERI) : 3-161 : Slow-wave Devices – Principles and Design : 4-0-0-4 Course Coordinator : V. Srivastava and L. M. Joshi Classification and high frequency limitations of conventional electron tubes. Formation and confinement of an electron beam. Slow-wave structures, couplers and RF windows. Beam-wave interaction mechanism. Spent beam collection. Efficiency enhancement by phase-velocity tapering and multi-stage depressed collection. Different types of devices, their operation, and characteristics, High power and wide bandwidth issues. Future trends. PHY(CEERI) : 3-162 : Fast-wave Devices – Principles and Design : 3-0-0-3 Course Coordinator : A. K. Sinha Merits of fast-wave devices over slow-wave devices. Operating principle of a gyrotron and design of its components: magnetron injection gun, beam tunnel, RF interaction cavity, magnetic field, non-linear taper, RF window, mode converter and collector. Beam-wave interaction and mode selection criteria. Other fast-wave devices: gyro-TWT, gyro-klystron, peniotron and FEL. Applications of gyro-devices and future trends. High Power Microwave (HPM) Devices. PHY(CEERI) : 3-163 : CAD of Microwave Tubes Laboratory : 0-0-4-2 Course Coordinator : R. K. Sharma and S. K. Ghosh Laboratory practices and safety considerations; Components design : electron guns, slow-wave structures, fast-wave structures, RF cavities, RF windows, collectors; Electron beam and RF wave interaction simulation; Thermal and structural design and simulation; CAD of complete tube; Computer aided engineering drawing. PHY(CEERI) : 3-164 : High Power Microwave Systems and Applications : 3-0-03 Course Coordinator : L. M. Joshi Special EW (Radar, ECM, ECCM) systems and their requirements in respect of microwave and millimeter wave devices; Types of jamming; Linear accelerators, Microtrons, Synchrotrons, Plasma heating systems, Proton accelerators, and Thermonuclear reactors; Other applications like imaging, spectroscopy, biomedical, industrial heating, electronic power conditioners, and modulators. PHY(CEERI) : 3-165 : Electron Emitters and Surface Characterization : 2-0-0-2 Course Coordinator : R. S. Raju Physics of electron emission, emission equation; Temperature limited and spacecharge limited emission; Methods of determining work function; Oxide coated cathodes, Dispenser cathodes, Field emitters, Explosive emission cathodes, Secondary emitters; Fabrication and characterization of cathodes; Life testing and surface analysis techniques; Nano-cathodes.

Final Draft

PHY(CEERI) : 3-166 : Plasma-Filled Microwave Sources : 2-0-0-2 Course Coordinator : Ram Prakash and U. N. Pal Plasma and its physical parameters; Saha equation and its relevance; Motion of charged particles in static and slowly varying electric and magnetic fields; Motion of relativistic charged particles; Types of gaseous discharge; Hollow-cathode discharge and other kinds of low-pressure discharges; General features of electrons emission, control and extraction of electrons and ions from plasma in DC and pulsed mode conditions; Plasma sources for axially symmetric electron beams; Plasma cathode electron gun (PCE-gun); Advantages of plasma filling in high power microwave devices; Operating principles, characteristics, and applications of different types of plasma-filled devices including the pasotron. PHY(CEERI) : 3-167 : Vacuum Microelectronic Devices : 2-0-0-2 Course Coordinator : R. K. Sharma Basic semiconductor technologies like reactive ion etching, photo-lithography, oxidation, CVD, sputtering, LIGA; MEMS technologies; Design considerations in vacuum microelectronic devices; Photonic band-gap structures, folded wave guide and ladder structures; Tera Hertz devices including reflex klystrons; Micro-fabricated devices like TWT and klystrino; Combination of vacuum and semiconductor technologies in microwave devices, including microwave power module and their applications. PHY(CEERI) : 4-001 : CSIR-800 Societal Programme : 0-0-8-4 Course Coordinator : Raj Singh A project needs to be undertaken in rural area for 6-8 weeks duration aligned to the CSIR-800 programme. The theme of the project may be chosen from the CSIR-800 document or from any other government department related to benefiting and empowering the economically lower 800 million Indians by way of S&T innovations. The aim is to interact with underprivileged people in the villages and propose solutions in the area of health, agriculture, energy, water, food, education, etc. PHY(CEERI) : 4-002 : Project Proposal Writing : 0-1-6-4 Course Coordinator : Raj Singh Definition of a scientific project proposal; Components of a proposal; Need and purpose of the proposal; Aims and objectives; Background and present status; Proposed methodologies and approaches; Scheduling and mile-stones; Resource allocation; Budgeting; Monitoring and evaluation mechanisms; Referencing and citing; Use of data, graphs, tables, figures; Proposal funding agencies and their formats. Every student needs to submit two proposals --- one related to PhD research topic and the second in any field of electronics.

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2. CSIR-CMMACS (Centre for Mathematical Modelling and Computer Simulation, Bengaluru)

Sr. No

Course No.

Course Title

L-T-P-C

1

PHY/MIS(CMMACS)1-001

Research Methodology

1-1-0-2

2

PHY(CMMACS) 2-241

Statistical and Computational Methods

2-1-0-3

3

PHY(CMMACS) 2-242

Global Navigation Satellite System 2-1-0-3 (GNSS) theory and its applications

4

PHY(CMMACS) 2-243

Applied Seismology and Geohazard

5

PHY(CMMACS) 2-244

Advanced mathematical methods in 1-2-0-3 weather and climate predictions

6

PHY(CMMACS) 2-245

Numerical Analysis Programming

7

PHY(CMMACS) 2-246

8

PHY/MIS(CMMACS)3-001

Advanced Self Study

0-2-4-4

9

PHY/MIS(CMMACS)-4-001

CSIR-800 Societal Programme

0-0-8-4

10

PHY/MIS(CMMACS)-4-002

Project proposal writing (I & II)

0-1-6-4

Final Draft

and

2-1-0-3

Fortran 3-0-0-3

Earthquake and Volcano Deformation

2-1-0-3

Brief Description of Physical Science Courses at CSIR-CMMACS (Course Level-Wise) PHY/MIS(CMMACS)- 1-001: Research Methodology : 1-1-0-2 Course Coordinator: P Goswami Introduction, Research terminology and scientific methods, different types and styles of research, role of serendipity, creativity and innovation, Scientific and critical reasoning skills, art of reading and understanding scientific papers, literature survey. Measurements in research - primary and secondary data. Quantitative methods and data analysis, Qualitative analysis, Communicating research results. Designing and implementing a research project. Ethics in research, Plagiarism, Case studies. Laboratory safety issues – lab, workshop, electrical, health & fire safety, safe disposal of hazardous materials. Role & importance of communication, Effective oral and written communication. Technical report writing, Technical/R&D proposals, Research paper writing, Dissertation/Thesis writing, Letter writing and official correspondence. Oral communication in meetings, seminars, group discussions; Use of modern aids; Making technical presentations. PHY(CMMACS) : 2-241 : Statistical and Computational Methods: 2-1-0-3 Course Coordinator: N K Indira Basic Concepts: Discrete and continuous data, Sample and Population, Events and Probability, Frequency, Table and Frequency distribution, Random variable and expectations, Measures of central tendency, dispersion and coefficient of variation, Moments and moment generating functions. Regression and Correlation: Linear regression analysis, Nonlinear regression analysis, Multiple regression Correlations. Probability and probability distributions: Discrete probability distributions and Continuous Probability distributions. Classical Time series analysis: Measurement of trend, Measurement of seasonal fluctuations, Measurement of cyclic fluctuations. Stochastic time series analysis: System definition, System analysis, Model formulation, Modelling procedure, Estimation and validation. Correlation systems: Principal component analysis, Factor analysis. Analysis of variance. One way classification and Two way classification. Statistical analysis and hypothesis testing. Sampling and sampling distributions, Parametric estimation, Tests of hypothesis, Nonparametric method. PHY(CMMACS) :2-242 : Global Navigation Satellite System (GNSS) theory and it applications to Geosciences: 2-1-0-3 Course Coordinator Sridevi Jade Introduction to GNSS geodesy, GNSS theory, GNSS reference frames, sources of errors and correction, positioning using GNSS observables, GNSS data collection, data processing and analysis, GNSS applications for Geoscience, Modelling of GNSS derived surface deformation.

Final Draft

Introduction to GNSS geodesy covers the state of art on Global Navigation Satellite systems, its components, geodesy, Military and Civil applications. GNSS reference frames: Introduction to celestial and terrestrial reference frames, Earth Centered Earth fixed reference frame and earths pole of rotation. Sources of errors and corrections: Introduction of positioning using GNSS satellites, errors involved covering orbit, clock errors, troposphere and ionosphere errors, miscellaneous errors. Positioning using GNSS observables: To determine the precise position and time, error correction, different types of positioning. GNSS data and processing theory: Models involved in data processing and analysis. GNSS applications to Geoscience: Surveying, continental deformation studies, landslide hazard mapping, Glacier dynamics, Volcano deformation, troposphere and ionosphere modeling, InSAR (Interferometric Synthetic Aperture Radar), GIS (Geographical Information System) etc. Modelling of GNSS deformation: brief introduction of different kind of modeling techniques that are currently being used. PHY(CMMACS): 2-243: Applied Seismology and Geo Hazard: 2-1-0-3 Course Coordinators: Imtiyaz A Parvez Basic concept of seismology, seismicity, wave propagation and seismic hazard using ground motion modeling and microtremors. Overview of Seismology and Seismotectonics: Earth and its Interiors, Plate Tectonics, Causes of Earthquakes, Seismic Waves, Earthquake Magnitudes, Earthquake Intensities, Seismicity patterns and tectonic settings, Overview of seismogenic source zones in India Basic concepts of Earthquake sources and wave propagation: Introduction to the Fourier Transform and its use in seismology, Double-couple force systems, Omegasquare and Haskell source models Directivity, Wave propagation and waveform modeling, Source parameters to determine from teleseismic modeling, Source time function and fault slip, Wave propagation at regional distances, Empirical study of regional wave propagation Earthquake Recurrence Statistics: Earthquake magnitude and magnitude scales, Seismometry, Gutenberg Richter relation Maximum magnitude, Characteristic earthquake models, Maximum earthquake magnitudes, Relationship of seismological parameters to field geology parameters, Poisson vs. other models of earthquake recurrence Seismic Hazard Analysis: Concept of Earthquake hazard analysis, Ground motion modelling for hazard analyses Role of Attenuation law, Probabilistic and Deterministic seismic hazard analysis, Uncertainties in hazard evaluation, Role of random scatter, Role of modeling uncertainty Hazard deaggregation, site effects and ground motion modeling.

Final Draft

PHY(CMMACS): 2-244 : Advanced mathematical methods in weather and climate predictions: 1-2-0-3 Course Coordinator : K Rameshan To introduce advanced mathematical methods used in weather and climate prediction. Introduction to weather and climate predictions, Statistics and Probability, Review Statistical Mechanics, Review Complexity and information theory, Basics. Liouville equation; Fokker-Plank Equation; Singular vectors; Stochastic Optimals. Chaos and deterministic Predictability; Ensemble forecasts; Nonlinear forecasts. PHY(CMMACS): 2-245: Numerical Analysis and Fortran Programming: 3-0-0-3 Course Coordinator : P S Swathi This is a programming-intensive course which will make the students write Fortran codes for numerical analysis topics. There is no separate lab component. Programming assignments will be integral to the course and not considered as lab assignments. The topics covered will include: Basics of computer floating point arithmetic, Fortran programming and debugging, Taylor series, solution of algebraic equation, linear systems – direct and iterative methods, eigen value problems, least squares and singular value decomposition, interpolation and extrapolation, numerical differentiation and integration, numerical solution of ordinary differential equations PHY(CMMACS): 2-246: Earthquake and Volcano Deformation: 2-1-0-3 Course Coordinator: Anil Earnest Theoretical concepts of earthquake faulting, stress in crust, mechanics of earthquakes, rupture propagation, earthquake clustering and migration, coulomb stress loading, the crustal deformation cycle, models of strain accumulation, earthquake cycle and recurrence times, observational techniques for strain and recurrence quantification, qualitative and quantitative seismo-tectonic analysis, mechanisms of various tectonic regime earthquakes, slow and tsunamigenic earthquakes, aseismic slip, seismic coupling, episodic tremor and slip, induced seismicity, mechanisms, volcanism - basics, structure and evolution of spherical magma chamber. PHY/MIS(CMMACS)- 3-001: Advanced Self Study:0-2-4-4 Course Coordinator: PhD Guide Aims to train the student on learning, on one's own, topics that are not formally taught in a course. This would involve primarily three components - collection of relevant literature on a chosen topic, organization of relevant material into a written report based on candidate's own critical understanding and finally presentation of the findings in front of wide audience in the form of a seminar. Thus communication skills are also expected to be honed up (4 credits)

Final Draft

PHY/MIS(CMMACS)-4-001: CSIR-800 Societal Programme: 0-0-8-4 Course Coordinator: Dr P Goswami / Dr Ehrlich Desa The students have to undertake a project in rural area for 6-8 weeks in line with CSIR-800 programme which is primarily prepared at empowering 800 million Indians by way of S & T inventions. The theme for the project may be chosen from CSIR-800 document and as per expertise available at individual laboratory. Students will choose the topics in consultation with Doctoral Advisory Committee (DAC). PHY/MIS(CMMACS)-4-002: Project proposal writing: 0-1-6-4 Course Coordinator: PhD Guide Two subject proposals to be prepared before comprehensive examination by selecting topics of high relevance and novelty, and will have state-of-the art review, methodologies, recommendations etc. (2 credits each)

Final Draft

3. CSIR-CSIO (Central Scientific Instruments Organization, Chandigarh) Sr. No. 1 2 3 4 5 6 7 8 9 10

Course No. PHY/ENG(CSIO)-1-001 PHY/ENG(CSIO)-1-311

Course Title

Research Methodology Mathematics for Engineers and Scientists PHY(CSIO)-2-311 Sensors and Actuators PHY(CSIO)-2-312 Optics and Opto-electronics Advanced Materials and Nano PHY(CSIO)-3-311 Science PHY(CSIO)-3-312 Photonic Devices and Systems PHY(CSIO)-3-313 Analytical Instrumentation PHY/ENG(CSIO)-3-001 Advanced Self Study PHY/ENG(CSIO)-4-001 CSIR-800 Societal Program PHY/ENG(CSIO)-4-002 Project proposal writing (I & II)

Final Draft

L-T-P-C 1-1-0-2 3-1-0-4 3-0-2-4 3-1-0-4 3-0-2-4 3-0-2-4 3-0-2-4 0-2-4-4 0-0-8-4 0-1-6-4

Brief Description of Physical Science Courses at CSIR-CSIO (Course Level-Wise) PHY/ENG(CSIO)-1-001: Research Methodology: 1-1-0-2

Course Coordinator: Dr HK Sardana Introduction to Research: Importance, study of literature, defining research problem, hypothesis formulation, experimental design Data Collection and Measurement: Methods and techniques, probability and probability distributions, sampling and sampling designs Data Analysis: Testing of hypothesis, statistical tests and analysis, data interpretation, multivariate analysis, model building, forecasting methods Report writing and Presentation: Ethics in research, Plagiarism, substance of reports, formats, referencing, oral presentation skills General practices followed in Research – literature and data management, Safety practices in the laboratory, Intellectual property rights (IPR). PHY/ENG(CSIO)-1-311: Mathematics for Engineers and Scientists:3-1-0-3

Course Coordinator: Dr GS Singh Calculus: Differential Calculus, Partial differentiation, Integral Calculus, Multiple integrals, Vector Calculus Complex Analysis: Complex numbers and functions, Matrices, Calculus of Complex Functions. Differential Equations: Differential equations of first order, linear differential equations, Differential equations of different type, series solution of differential equations and special functions, partial differential equations. Series & Transforms: Series, transforms, and complex transforms. PHY(CSIO)-2-311: Sensors and Actuators:3-0-2-4 Course Coordinator: Dr Sunita Mishra Sensor Technologies: Physical principles & basic mechanisms in sensor systems, semiconductor processing, processing of ceramic and glasses, thin and thick film technologies, processing of micro-sensors Sensor Structures: Impedance type, semiconductor based, resonance based, electro-chemical cell, colorimetric and fibre optic sensors. Sensing Effects and Performance: Dielectric, sorption, conductivity, resistivity, optical behaviour, selective chemical sensing, multi-array sensing, Transduction principles, transducer characteristics, classification of transducers, methods for characterisation of transducers-performance characteristics, static & dynamic characteristics, error analysis. Actuators: Principles of actuation mechanism, architecture of control electronics, development methodology of motor/actuator control, micro actuators, stepper motors, brushed DC motors, brushless DC motors and hydraulic and pneumatic actuators, Bimorph actuators. Sensor Applications: Mechanical, acoustic, temperature, IR, humidity, magnetic material, MEMS, ion-selective, medicine and biology.

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PHY(CSIO)-2-312: Optics and Opto-electronics:3-1-0-3

Course Coordinator: Subhash Jain Basic optics: Reflection and refraction of plane waves, polarization, diffraction; two-beam and multiple beam interference, Fabry-Perot interferometer, micro-optic components, laser basics and applications. Optical fibre properties: Fibre characterisation techniques, directional couplers, connectors, splices, fibre polarization components, wavelength division multiplexing, fibre gratings, optical spectrum analyzer, OTDR. Light-matter interaction: Interaction of radiation with material, optical sources and detectors, Q-switching and mode locking in lasers, light detection techniques, fibre optic and radiation sensors, photonic crystals, holey fibre, fibre half-block and birefringent fibres, electro-optic effects, acousto-optic effect, nonlinear optics and parametric amplification, fibre amplifiers and laser systems. PHY/ENG(CSIO)-3-001: Advanced Self Study:0-2-4-4 Course Coordinator: PhD Guide The main focus of this course is to encourage self-learning in the niche areas of the candidate’s interest. The candidate is expected to do an extensive literature survey in the chosen research area and submit an written report of the work and present the work to group of experts in the form of a seminar. PHY(CSIO)-3-311: Advanced Materials and Nano Science:3-0-2-4 Course Coordinator: Dr Akash Deep Alloys and their properties: Ferrous & non-ferrous alloys, shape memory alloys, chemical composition, mechanical properties, electrical and magnetic properties, heat treatment, metal processing, elastic behaviour, optical materials. Semiconductor Materials: Semiconductor materials- electronic and optical properties. Polymers: Chain growth polymers, step growth polymers, photochromic polymers & conducting polymers, optical applications, photochromic lenses, liquid crystal polymers, photo simulated shape changes. Nano structured materials: Characterization techniques, thin film growth, coating, powders, semiconductor nanostructures, fabrication, quantum dot processing technologies, bio-nano materials and applications. PHY(CSIO)-3-312: Photonic Devices and Systems:3-0-2-4

Course Coordinator: Randhir Bhatnagar Photonic Devices: Optical and Photonic band gap materials, Device Structures and Characteristics, Optical Amplifiers, Distributed Feedback Laser, Distributed Bragg Reflector Laser. Biophotonics: Photobiology, Fluorescence and Evanescent Biosensors, FBG/LPG based sensing, Bioimaging, Principle and Technique of Confocal Microscope, Raman Microscope, Near Field Scanning Optical Microscopy, Bio-Nano-Photonics and its applications.

Final Draft

Photonic Sensors and Systems: Raman, Brillion and Rayleigh scattering based Sensors and Systems, FBG Interrogation Techniques and Systems, Surface Plasmon Resonance Sensors and Systems. PHY(CSIO)-3-313: Analytical Instrumentation:3-0-2-4

Course Coordinator: Dr AK Paul Introduction: Basics of analytical instrumentation, use of computers in analytical instrumentation, statistical techniques, atomic emission and absorption spectroscopy (UV-visible, NIR, IR, FTIR, X-ray). Elemental analysis: Detection of atoms, molecules and aerosols, glow discharge spectroscopy for elemental analysis Separation techniques: Chromatography (gas, ion and liquid) and headspace analysis. Electro-Chemical Instrumentation: Introduction and overview of electrode processors, kinetics of electrode reactions, potentials sweep methods, impedance spectroscopy. Microscopy: Concept of scanning electron microscopy, transmission electron microscopy, tunnelling microscope and atomic force microscope, applications in material characterization. PHY/ENG(CSIO)-4-001: CSIR-800 Societal Programme:0-0-8-4

Course Coordinator: Dr Pawan Kapur The students have to undertake a project in rural area for 6-8 weeks in line with CSIR-800 programme which is primarily prepared at empowering 800 million Indians by way of S & T inventions. The theme for the project may be chosen from CSIR-800 document and as per expertise available at individual laboratory. Students will choose the topics in consultation with Doctoral Advisory Committee (DAC). PHY/ENG(CSIO)-4-002: Project proposal writing:0-1-6-4 Course Coordinator: Dr Pawan Kapur Two subject proposals to be prepared before comprehensive examination by selecting topics of high relevance and novelty, and will have state-of-the art review, methodologies, recommendations etc. (2 credits each)

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4. CSIR-IMMT (Institute of Minerals and Materials Technology, Bhubaneswar) Sr. No. 1

Course No.

Course Title

L-T-P-C

PHY(IMMT)-1-001

Research Methodology

2-0-0-2

2

PHY(IMMT)-2-346

Computational Methods & Numerical Analysis

3-0-2-4

3

PHY(IMMT)-2-347

3-0-2-4

4

PHY(IMMT)-2-348

Technologies for mineral resource utilization Material characterization techniques

5 6

PHY(IMMT)-2-349 PHY(IMMT)-2-350

Recycling of Material Resources

3-0-2-4 3-1-0-4

3-0-2-4

Process Instrumentation & Control 7

PHY(IMMT)-2-351

3-0-0-3 Science for engineers

8

PHY(IMMT)-2-352

Fundamentals of Engineering Analysis

3-0-0-3

9

PHY(IMMT)-2-353

Process design & simulation

3-0-2-4

10

PHY(IMMT)-2-354

Advanced Extraction Methods

3-0-0-3

11

PHY(IMMT)-2-355

Advanced Topics in Materials Resource Engineering

3-0-2-4

12 13 14

PHY(IMMT)-2-356 PHY(IMMT)-2-357 PHY(IMMT)-3-346

Energy & environment Mineralogy and mineral chemistry Computational Fluid Dynamics

3-0-2-4 3-0-2-4 3-0-2-4

15

PHY(IMMT)-3-347

Advanced Materials: Characterization and Processing

3-1-2-4

16

PHY(IMMT)-3-001

Advanced Self study

0-2-4-4

17 18

PHY(IMMT)-4-001 PHY(IMMT)-4-002

CSIR-800 Societal Programme Project proposal writing (I & II)

0-0-8-4 0-1-6-4

Final Draft

Brief Description of Physical Science Courses at CSIR-IMMT (Course Level-Wise) PHY(IMMT)-1-001: Research Methodology: 2-0-0-2 Course Coordinators: Dr. D.B. Ramesh, Dr. D. P. Sandha, Dr. D.P. Das 1.

Research Methodology - Introduction  Meaning, Concept, Need  Historical Research  Survey Research  Experimental Research  Fundamental and Applied Research

2.

Literature Search & Review of Literature

3.

Research Tools  Measurement of Variables  Presentation of Data  Statistical Techniques – All Basic Techniques, Null hypothesis, Error Analysis, Interval estimation, Statistical Significance, Examples: Analysis of variance (ANOVA), Chi-squared test, Correlation, Factor analysis, Mann–Whitney U, Mean square weighted deviation (MSWD), Pearson product-moment correlation coefficient, Regression analysis, Spearman's rank correlation coefficient, Student's t-test and z-test, Time series analysis  Statistical Packages: o MS Excel - Introduction, Getting Data into Excel, Activating the Data-Analysis Tools, Using Excel to Determine a Confidence Interval, Using Excel for t-Tests of Hypotheses, The t-Test for Independent Samples, The t-Test for Dependent (and MatchedPair) Samples, Using Excel for ANOVA, Using Excel for Correlation, Using Excel for Linear Regression, Using Excel for Chi-Square Tests, The Chi-Square Goodness-of-Fit Test and the Chi-Square Test of Association o MATLAB - Introduction and Key Features, Developing Algorithms and Applications, Analyzing and Accessing Data, Visualizing Data, Performing Numeric Computation, Publishing Results and Deploying Applications

4.

Research Types and Methods  Observation Method  Questionnaire Method  Interview Method  Experimental Method

5.

Research Process  Designing a Research: Characteristics, Purpose  Research Plan  Analysis and Testing

Final Draft

6.

 Quantitative Methods and Data Analysis  Qualitative Analysis Communicating Research Results  Journal paper  Thesis  Project proposal  Report  Web publishing  Seminar and Oral presentations

7.

Research Ethics and Plagiarism

8.

Case Studies

PHY(IMMT)-2-346: Computational Methods & Numerical Analysis: 3-0-2-4 Course Coordinators: Dr. D. P. Das, Mr. S. Rath Computation & Programming: Notions of syntax and semantics of programming languages, Concept of algorithm, Systematic development of programs, Computer Architecture & Memory management, Object Oriented Programming & Data structure, parameter passing mechanisms, Program design practices. Numerical Scientific Computing: Numerical differentiation & integration, Solving polynomial equations, Computational matrix, Transforms Computer Graphics: Input / Output devices, Raster & Vector Graphics, Drawing algorithms; Windowing and 2D/3D clipping. 2D & 3D Geometrical Transformations, Viewing Transformations, Animation Techniques Statistical Analysis: Statistical Concepts, Conditional Probability and independence, Regression Analysis, Design of Experiments, Support Vector Machine, Statistical Inference, Optimisation. Practical/ Lab Work: Statistical Analysis using standard statistical package, application modelling using MATLAB, application programming practices with standard graphics libraries like open GL. PHY(IMMT)-2-347: Technologies for Mineral Resource Utilization: 3-0-2-4 Course Coordinators: Mr. P.S.R. Reddy, Prof. D.D. Misra, Prof. B.K. Mishra Particulate technology, particle size distribution, sizing methodology, size-reduction and classification processes; Particulates in suspension, stability, Rheology and settling; Solid-liquid separation methods; Physics, chemistry, and engineering design as applied to gravity, magnetic, electrostatic, and froth flotation processes

Final Draft

PHY(IMMT)-2-348: Materials Characterization Technique: 3-0-2-4 Course Coordinator: Dr. B. K. Mahapatra Size and surface area analysis; Interaction of X-rays with matter, diffraction techniques and applications; Optical principles of microscopy; electron diffraction, imaging (various contrasts), determination of crystal structure, burgers vector, electron beam-specimen interactions and other applications of Transmission Electron Microscopy; Applications of Scanning Electron Microscopy and, Electron Probe Micro-Analyser; Principles of Quantitative Microscopy: Overview of other characterization techniques such as Auger electron spectroscopy, Scanning Tunneling Microscopy, Atomic Force Microscopy. PHY(IMMT)- 2-349 : Recycling of Material Resources: 3-0-2-4 Course Coordinator: Dr. K. Sanjay Mining and metallurgical wastes classification, investigation and evaluation of waste deposits, waste and circulatory management during recycling. Unit operations involving materials recycling processes such as pre-treatment (physical and chemical), roasting, calcination, sintering, leaching, solid-liquid separation; Solution, concentration and purification techniques—precipitation, cementation, solvent-extraction, evaporation, crystallization, electrowinning, electroremediation; Resources and recycling technologies across the major materials sectors, and case studies including wastes in steel and aluminium production; Recycling of E-wastes and secondaries; Economic evaluation and project implementation: Flow-sheet development, mass and energy balance, costing, techno-economic feasibility report (TEFR) preparation, financial investment in waste recycling, project planning and implementation, work safety. PHY(IMMT)-2-350: Process Instrumentation & Control: 3-1-0-4 Course Coordinator: Dr. D. P. Das Introduction to instrumentation in process industry, Different types of sensors and actuators, Computerized data acquisition, Monitoring and analysis of data (Time series and spectral analysis), Process control, PID Control, Introduction to PLC, SCADA & DCS, Networking and communication in industry, Artificial neural network & Fuzzy logic based control, Laboratory work. PHY(IMMT)-2-351: Science for engineers: 3-0-0-3 Course Coordinator: Dr. Bikash K. Jena Concepts of atomic and molecular energy levels leading to description of plasma state, plasma physics—thermal and non-equilibrium plasma, plasma diagnostics, methods of plasma processing of materials and minerals; Industrial plasmas, new concepts of resource utilization using plasma, Crystal structure and defects, electron Final Draft

and hole in lattices, Band gap module and tailoring : -optical and electrical, variable band gap. Structure and Bonding; Molecular basis of chemical reactions, reaction kinetics, structural effect on reactivity; Complexation concepts, Spectroscopy, Metals in biological domain, Molecular engineering; Computational approaches for structurefunction correlation, Surfaces and interfaces, Chemical theories involved in solution, concentration and purification, Micelles, surfactants and their application for bulk processing of mineral resources. Cell types structure and function; Bio-molecules: composition and bonding; Overview of amino acids, proteins, carbohydrates, nucleic acids, lipids, enzymes, vitamins and minerals; DNA replication; Membranes, Introduction to bio-mineral processing. PHY(IMMT)-2-352: Fundamentals of Engineering Analysis: 3-0-0-3 Course Coordinator: Dr. Swati Mohanty Fundamental concepts of fluid flow, heat and mass transfer; Shell balance approach for molecular and convective transport processes; Formulation and solution of ordinary and partial differential equations that describe physical systems of importance in engineering; some applications to minerals and materials processing Numerical methods: finite difference, numerical solution of ordinary and partial differential equations. PHY(IMMT)-2-353: Process Design & Simulation: 3-0-2-4 Course Coordinator: Prof. B. K. Mishra, Dr. C. Eswariah Preliminary resource evaluation methods; Identification and development of process flow sheet; Elementary evaluation of plant performance; Spread-sheet development for plant data analysis; Introduction to simulation environment using MODSIM, simulator structure, numerical analysis of simulation, sequential method of simulation, practical application of plant simulation; Materials and energy balance, mass balance smoothing, data reconciliation in terms of grade and recovery, analysis of complex flowsheet for mass balancing, examples of material balance smoothing; Application of modeling and residence time distribution concepts for plant data interpretation; Parameter estimation: linear regression, one, two, and multilinear regression; models nonlinear in parameters; Case studies of typical process plant design and operation. PHY(IMMT)-2-354: Advanced Extraction Methods: 3-0-0-3 Course Coordinator: Dr. R. K. Paramguru Fundamentals of commercially important nonferrous pyrometallurgical extraction processes; Thermodynamics of high-temperature processes and solid-gas reaction kinetics; Heterogeneous kinetics, multi-phase systems, Electrodics, Semiconductor Final Draft

electrochemistry; Application: roasting, sulphide-oxide-sulphate systems, oxidechloride systems, smelting, kinetic analysis, bath smelting, dynamic contact anglefree energy correlation; Electro-smelting—present practice and future trends; Direct electro winning, possible electrode systems, conduction types, future trends. PHY(IMMT)-2-355:Advanced Topics in Materials Resource Engineering:3-0-2-4 Course Coordinator: Dr. S.K. Singh Plasma Processing Introduction, Basic plasma and gas discharge concepts, Glow discharge plasmas, Thermal plasmas, Plasma torches and sprays, Plasma chemistry, etching and polymerization, Plasma coatings, Diamond and diamond-like films, Diagnostics/Probes, Plasma Spraying, Preparation of nano powders, Plasma smelting, Plasma sintering Powder Metallurgy Production of metal and alloy powder, particle size & shape, microstructure, Powder compaction, Sintering (Solid state sintering & Liquid phase sintering), Hot pressing, Sintering furnaces & atmospheres, Applications of powder metallurgy. Corrosion Science & Engineering General introduction, Electrochemical reactions, Thermodynamic concepts, Eh-pH diagram, Prevention of corrosion Rheology Fundamentals, Types of viscometers and rheometers, Applications PHY(IMMT)-2-355: Energy & Environment: 3-0-2-4 Course Coordinator: Dr. B. C. Acharya Important Indian minerals & related environmental issues; Environmental impact due to mining in Orissa; Case study on graphite resources of Orissa and environmental management, Environmental issues related to mining, processing and products – solid wastes, Environmental impact analysis and management plan, Case studies related to environmental management of minerals and materials industries; Effluent treatment (nutrients removal ) through microbial activity, Vulnerability and adaptation technologies for sustainable development, Pollution generation and management – Effluents, Environmental laws and global issues related to environment, Conservation of energy in different production and processing steps, Energy audit in mineral and material processing industries. PHY(IMMT)-2-357: Mineralogy and Mineral chemistry: 3-0-2-4) Course Coordinator: Process mineralogy, Liberation Studies using QEMSCAN, Mineral chemistry using EPMA, Identification of mineral phases through XRD. Final Draft

Geochemistry :Chemical composition of the Earth, elementary statistics for geochemistry; major, minor and trace elements including rare earth elements; element partitioning between minerals and melts; petrogenesis, Geochemical Classification of elements, Geochemical differentiation, Isomorphism, Polymorphism, Atomic substitution and Geochemical cycle. Analytical Geochemistry: Chemical analysis of rocks and minerals, digestion techniques, preparation of standards, estimation of major oxide percentages using spectrophotometric /flame photometric and titrimetric methods. Preparation of calibration curves. Gravimetric estimation of silica and R2O3. Determination of noble metals. Introduction to Neutron Activation Analysis, principles of ICP, XRF & AAS analysis. Statistical Methods in Geosciences: Introduction to probability: random experiments, events, sample space, definitions of probability. Conditional probability and independence of events, Bayes theorm. Random variables, discrete and continuous probability distributions, joint probability distributions, conditional probability distributions. Mathematical expectation, moment generating and characteristic functions. Binomial, Poisson, Normal, Gamma, Exponential, Hypergeometric, Multinomial, Chi-square, t, and F distributions. Introduction to statistical inference, sampling distributions, point and interval estimation, hypothesis testing involving one and two univariate populations. Linear models ANOVA. Linear and multiple regression. Introduction to multivariate techniques PCA, factor analysis, linear discriminant analysis, classification PHY(IMMT)-3-001: Advanced Self Study:0-2-4-4 Course Coordinator: PhD Guide PHY (IMMT)-3-346: Computational Fluid Dynamics: 3-0-2-4 Course Coordinator: Dr. Swati Mohanty Introduction to Computational fluid dynamics; Conservation equations: momentum, energy and mass balance equations; Discretization methods: Finite difference method, Finite element method, Finite volume method; Structured and unstructured grid; Multiphase flows: fluid-fluid, fluid-solid; Turbulence modeling: Direct Numerical Simulation, Large Eddy Simulation, Reynolds Averaged Navier Stokes model; CFD modelling of some mineral and material processing unit operations; Introduction to CFD software. PHY(IMMT)-3-347: Advanced Materials: Characterization and Processing: 3-12-4 Course Coordinator: Dr. B. B. Nayak Theory: Fundamentals of crystallography, crystal structure and structure determination by XRD, electron diffraction and neutron diffraction in polycrystalline Final Draft

materials, stereographic projection and pole figures, orientation and texture analysis, structure of metals, alloys, solid solution, concept of amorphous, glassy and nano materials and their characterization, defects in crystals, theory of dislocation, Burger vector, plastic deformation, stress measurement by XRD, strengthening mechanism, cold working and heat treatment of steel, hardness and tensile test of steel, concepts in fracture mechanics and fracture determination methods, S-N curve, low cycle fatigue, fatigue mechanism. Practical: Study of types of high temperature furnaces including plasma furnace, induction and vacuum induction furnace, study and determination of vacuum in rotary and diffusion pumps, high temperature determination by thermocouple and pyrometer, morphology and microstructure observation by various microscopy methods (SEM, TEM, AFM, optical), XRD, Raman spectroscopy and identification of impurities and precipitates in metals, microhardness and nanoindention measurements, tensile, fracture toughness and fatigue tests of steel.

Final Draft

5. CSIR-NCL (National Chemical Laboratory, Pune) Sr.No. 1 2 3

Course Code PHY(NCL):1-001 PHY(NCL):1-416 PHY(NCL):1-417

4

PHY(NCL):1-418

5

PHY(NCL):1-419

6 7 8 9

PHY(NCL):2-416 PHY(NCL):2-417 PHY(NCL):2-418 PHY(NCL):2-419

10

PHY(NCL):2-420

11

PHY(NCL):2-421

12 13 14 15 16 17 18 19

PHY(NCL):2-422 PHY(NCL):2-423 PHY(NCL):2-424 PHY(NCL):3-416 PHY(NCL):3-417 PHY(NCL):3-418 PHY(NCL):3-419 PHY(NCL):3-420

20 21 22 23 24 25

PHY(NCL):3-421 PHY(NCL):3-422 PHY(NCL):3-423 PHY(NCL):3-424 PHY(NCL):3-425 PHY(NCL):3-426

26 27 28 29

PHY(NCL):3-427 PHY(NCL):3-428 PHY(NCL):4-001 PHY(NCL):4-002

Final Draft

Course Title Research Methodology Analytical Tools and Instrumentation Basic mathematics and numerical methods Basic Chemistry for Interdisciplinary sciences Introduction to Nanoscience and Nanotechnology Advanced Quantum Mechanics Advanced Materials Science Advanced Surface Science Advanced Materials Characterization Techniques Advances in Nanoscience and Nanotechnology Thermodynamics and Statistical Mechanics Composite Materials Carbon Allotropes Surface Characterization Techniques Mathematical Methods Numerical Methods Electronic Structure Theory Molecular Modeling and Simulation Materials and Devices for Energy Conversion Functional Ceramics Modern Magnetic Materials Porous Structures Alternate Energy Materials Polymers and Colloidal Solutions X-Ray Diffraction and Structure of Solids NMR Spectroscopy Small Angle Scattering Techniques CSIR-800 Programme Project Proposal Writing (I & II)

L-T-P-C 2-0-0-2 2-0-0-2 2-0-0-2 1-0-0-1 1-0-0-1 3-0-0-3 3-0-0-3 2-0-0-2 3-0-0-3 2-0-0-2 2-0-0-2 2-0-0-2 1-0-0-1 1-0-0-1 2-0-0-2 2-0-0-2 2-0-0-2 2-0-0-2 2-0-0-2 1-0-0-1 1-0-0-1 2-0-0-2 2-0-0-2 2-0-0-2 2-0-0-2 2-0-0-2 2-0-0-2 0-0-8-4 0-0-8-4

Brief Description of Physical Science Courses at CSIR-NCL (Course Level-Wise) PHY(NCL):1-001: Research Methodology: 2-0-0-2

Course Coordinator: Dr. P. A. Joy Good laboratory practices, Safety in the laboratory, First Aid in the laboratory, Maintenance of laboratory records, Scientific literature management, Communication skills (scientific writing and presentation), Intellectual property management & planning, Ethics in Science, Computer applications and tools, Statistical methods & Data analysis PHY(NCL):1-416: Analytical Tools and Instrumentation : 2-0-0-2

Course Coordinator: Dr. P. A. Joy Thermal methods (TG, DTG, DTA, TMA, DSC), X-ray methods (XRD, XRF, SAXS), NMR (1H, 13C) and other Spectroscopic methods (EPR, IR, UV, Fluorescence), Chromatographic methods (TLC, GC, LC), Mass spectroscopy, Electron Microscopy (SEM, TEM), Electron Probe Micro Analysis (EDS, WDS), Quantitative Analysis (AAS, ICP, CHN) PHY(NCL):1-417: Basic mathematics and numerical methods: 2-0-0-2

Course Coordinator: Dr. Sarika Bhattacharya Determinants and Matrices, Complex Variables, Vector analysis, Infinite Series, Special Functions, Differential Equations, Interpolation and Approximation, Numerical differentiation and Integration, Basic Linux, Introduction to Algorithms, basic programming, Shell and Shell Scripting, Network Computing and Parallel Computing, Matlab/Scilab/Octave/Gnuplot PHY(NCL):1-418: Basic Chemistry for Interdisciplinary sciences: 1-0-0-1

Course Coordinator: Dr. P. A. Joy Basics of inorganic, organic, physical and biochemistry, Nomenclature (IUPAC), molarity, molality and normality, types of bonding, Ionic, covalent and non-bonding interactions, Acids and bases, Atomic structure, periodic table and periodic properties, stoichiometry, chemical reactions and kinetics, solvent effects, functional groups in organic compounds, general named reactions and reaction mechanisms, carbohydrates, lipids, proteins, nucleotides, enzymes, photosynthesis PHY(NCL):1-419: Introduction to Nanoscience and Nanotechnology: 1-0-0-1

Course Coordinator: Dr. B. L. V. Prasad General considerations, Introduction, definitions, consequences of size reduction, Properties: structural, thermodynamic, optical, electrical and magnetic properties, Methods of synthesis, Surface modifications, factors governing the stability and assembly, Characterization of nanomaterials, Applications of Nanomaterials PHY(NCL):2-416: Advanced Quantum Mechanics: 3-0-0-3

Course Coordinator: Dr. Nayana Vaval Revision of Hydrogen atom and particle in box (1D and 3D), Approximate methods in quantum mechanics; Non degenerate perturbation ; Perturbation treatment of the Helium atom ground state and first excited state; Variation method for helium atom ground state; Comparison of perturbation and variation method, Structure of many electron wave function, Antisymmetry, Valence bond theory for homo and hetero nuclear diatomic molecules; Molecular orbital theory Comparison of MO and VB theory; Final Draft

Introduction to density functional theory; Hartree Fock theory, Overview of methods beyond Hartree Fock theory; Configuration Interaction; Many body perturbation; Coupled cluster PHY(NCL):2-417: Advanced Materials Science: 3-0-0-3

Course Coordinator: Dr. Nandini Devi Crystal systems and space groups, Close packing and various simple structure types like AB, AB2, AB3 and complex structural types ABX3, AB2X4, etc. Factors affecting crystal structures, Common preparative methods; X-ray diffraction and Electron microscopy, Defect structures, colour centers, reciprocal lattices, Properties of solids – Band theory, metals, insulators, semiconductors, dielectric and ferroelectric properties, magnetic properties, optical properties, ionic conduction; structure-processing-property correlations. PHY(NCL):2-418: Advanced Surface Science: 2-0-0-2

Course Coordinator: Dr. C. S. Gopinath Introduction to Surface Science - Surface phenomena - Adsorption, Desorption, Adsorption Models, Special properties of surfaces and interfaces, Electronic structure of surfaces, Surface modification and its applications, Nanoscale catalysis and applications, Surface spectroscopy and microscopy tools for nanocatalysis PHY(NCL):2-419: Advanced Materials Characterization Techniques: 3-0-0-3

Course Coordinator: Dr. Pankaj Poddar Optical Microscopy, Electron microscopy: TEM, HRTEM, SEM, STEM, EDX, FIB, e-beam lithography, Scanning probe microscopy: AFM, STM, MFM, confocal, etc, Raman spectroscopy/microscopy, Thermal analysis techniques, Magnetic measurements, Electrical measurements, Spectroscopic ellipsometry. PHY(NCL):2-420: Advances in Nanoscience and Nanotechnology: 2-0-0-2

Course Coordinator: Dr. B. L. V. Prasad Low-dimensional structures: Quantum wells, Quantum wires, and Quantum dots, Nano clusters & Nano crystals, fullerenes, carbon nano tubes and graphene, Nano Composites, synthesis and characterization techniques, Properties at Nano Scales and comparison with bulk materials, fabrication techniques, general applications, nanomaterials in biology. PHY(NCL):2-421: Thermodynamics and Statistical Mechanics: 2-0-0-2

Course Coordinator: Dr. Neelanjana Sengupta Introduction: Thermodynamics – A Macroscopic Theory of Matter; Laws of Thermodynamics, Ideal Gas Laws, Specific Heat Capacities; Concept of Free Energy, Hamiltonian Mechanics, Equilibrium Distributions and Ergodic Hypothesis, Ensembles, Thermodynamic Functions and the Distribution Function, g(r),Imperfect Gases, Kinetic Theory of Gases, Time Dependent Processes, Phase Transitions PHY(NCL):2-422: Composite materials: 2-0-0-2

Course Coordinator: Dr. P. A. Joy Concept of Composite materials, Various types of composites, Classification based on Matrix Material: Organic Matrix composites, Polymer matrix composites (PMC), Carbon matrix Composites or Carbon-Carbon Composites, Metal matrix composites (MMC), Ceramic matrix composites (CMC); Classification based on reinforcements: Fiber Reinforced Composites, Fiber Reinforced Polymer (FRP) Composites, Laminar Composites, Particulate Final Draft

Composites, Reinforcements/Fibers ,Types of fibres, Multiphase fibers, Whiskers and Flakes, Mechanical properties of fibres, Processing of Advanced composites, Metal Matrix Composites: Casting – Solid State diffusion technique, Cladding – Hot isostatic pressing; Ceramic Matrix Composites: Liquid Metal Infiltration – Liquid phase sintering; Carbon – Carbon composites: Knitting, Braiding, Weaving; Polymer matrix composites: Preparation of Moulding compounds and prepregs – hand lay up method – Autoclave method – Filament winding method – Compression moulding – Reaction injection moulding, Processing and characteristics of nanocomposites, hybrid composites, functionally graded composites, smart and functional composites. PHY(NCL):2-423: Carbon Allotropes: 1-0-0-1

Course Coordinator: Dr. P. A. Joy Synthesis, characterization, structure, properties and applications of: Diamond, Graphite, Amorphous carbon, Charcoals, Fullerene and related compounds, Carbon nanotubes, Graphene. PHY(NCL):2-424: Surface Characterization Techniques: 1-0-0-1

Course Coordinator: Dr. C. P. Vinod XPS, LEED, XAS, SEM, AFM, TEM, NSOM, SPR, SERS, static and dynamic contact angle measurements, Ellipsometry. PHY(NCL):3-416: Mathematical Methods: 2-0-0-2

Course Coordinator: Dr. T. G. Ajithkumar Determinants and Matrices : Orthogonal Matrices, Hermitian Matrices, Unitary Matrices, Dioganalisation of Matrices, Vector analysis : Scalar and Vector product, Triple scalar and vector product, Gradient, Divergence, Curl, Vector Integration, Gauss Theorem, Stokes Theorem. Vector Analysis in Curvilinear coordinates and Tensors, Infinite Series: Fundamental Concepts, Convergence tests, Taylors expansion, Power Series, Special Functions: Gamma Function, The Beta Function, Differential Equations: Series SolutionFrobnius Method, Bessel Functions, Legendre Functions, Hermite Functions, Laguerre Functions, Fourier Series, Applications of Fourier Series, Fourier Transforms PHY(NCL):3-417: Numerical Methods: 2-0-0-2

Course Coordinator: Dr. Sudip Roy Fortran and Linux basics, Solution to the linear algebraic equations, Eigen Values problems, Interpolation and extrapolation, Random number and sorting, Minimization and maximization of functions, Modeling of data PHY(NCL):3-418: Electronic Structure Theory: 2-0-0-2

Course Coordinator: Dr. P. A. Joy Post-Hartree-Fock methods: Moller-Plesset perturbation theory (MP2, MP3, and MP4), Configuration Interaction (CI), Coupled-Cluster single double (triple) (CCSD(T))– performance of various methods for the prediction of van der Waal and hydrogen bonding interactions, spectral properties. Density functional theory based methods: Hybrid and Minnesota functional – Application of DFT methods (excitation energy calculations). Density functional methods with Dispersion correction (Grimme’s approaches). Car-Parrinello Molecular Dynamics (CPMD) and Born-Oppenheimer Molecular Dynamics (BOMD).

Final Draft

PHY(NCL):3-419: Molecular Modeling and Simulation: 2-0-0-2

Course Coordinator: Dr. P. A. Joy Molecular Mechanics: Features of molecular mechanics - Force Fields: Bonds structure and bending angles, Electrostatic Vander Waals and non-bonded interactions, Hydrogen bonding - Derivatives of molecular mechanics energy function - Calculating thermodynamic properties - Force Field for inorganic systems - Energy minimization, Molecular Dynamics Simulation: Molecular Dynamics using simple models, Molecular Dynamics with continuous potentials, Solvent effects, Conformational changes, Thermostats, Barostas, Lincs and shake algorithms, Monte Carlo simulation Methods, sorption, Applications of Molecular Modeling PHY(NCL):3-420: Materials and Devices for Energy Conversion: 2-0-0-2

Course Coordinator: Dr. K. Krishnamoorthy Design of organic and Inorganic semiconductors, Approaches to process organic semiconductors by covalent and non covalent modifications , band edges and band gaps, Modulation of charge transport properties, kinetics of electron transfer, Design of small molecule dyes for DSSC, Electron transfer at interfaces, Transistors and solar cells, Fabrication of Devices, Device characterisation using dark current, IV curves under illumination, IPCE, Calculation of Voc, Jsc, Vpp, Ipp, FF and Pmax. hybrid solar cells PHY(NCL):3-421: Functional Ceramics: 1-0-0-1

Course Coordinator: Dr. P. A. Joy Advanced Electronic Ceramics, high temperature ceramic super conductors, Dielectric ceramics, microwave ceramics, low k materials, SOFC materials, solid-ionic conductors, phosphor materials, Impedance analysis, varistors, sensors, ceramic magnets, thermal shock resistance and super plastic ceramics. PHY(NCL):3-422: Modern Magnetic Materials: 1-0-0-1

Course Coordinator: Dr. P. A. Joy Types of magnetism, molecular field theory, measurement techniques, magnetoresistance (AMR, GMR, CMR, TMR), hard and soft magnets, magnetostriction, New magnetic materials, applications. PHY(NCL):3-423: Porous Structures: 2-0-0-2

Course Coordinator: Dr. Rahul Banerjee Definitions, Micro-Porous and Mesoporous Solids, Structural Chemistry of Zeolite Framework Types, MOFs, COFs, Synthesis, Structure Determination, Role of the Structuredirecting Agents, The Chemistry of Microporous Framework Solids, Adsorption and Diffusion, Catalytic Applications, hydrogen storage, separation, CO2 sequestration, sensors, PHY(NCL):3-424: Alternate Energy Materials: 2-0-0-2

Course Coordinator: Dr. P. A. Joy Energy scenario, Non-renewable and renewable energy sources; description of renewable sources and their importance. Technologies for biomass energy conversion, Solar energy, Wind Turbines, Geothermal Technologies; Applications; Sustainable sources of hydrogen; Fuel cell technologies; Hydrogen storage and distribution; Applications and feasibility assessment; Science, technology and policy of energy conservation; Strategies for enhancing role of renewable energy. Final Draft

PHY(NCL):3-425: Polymers and Colloidal Solutions: 2-0-0-2

Course Coordinator: Dr. K. Guruswamy Intermolecular forces and potentials, Overview of Statistical physics, DLVO theory, charged colloids, Poisson Boltzmann theory, Debye radius, Bjerrum length, electrophoresis, zeta potential, diffusion, Hydrodynamic interactions. Brief overview of Phase transitions in hard sphere colloids, Random walk, self avoiding random walk, flexible polymers, persistence length, Excluded volume interactions, Polymer solutions in the dilute limit/semi-dilute limit, Entropy of mixing, theta temperature, rubber elasticity, Polyelectrolytes, polymer at surfaces: Brushes, polymer dynamics. PHY(NCL):3-426: X-Ray Diffraction and Structure of Solids: 2-0-0-2

Course Coordinator: Dr. Rahul Banerjee Introduction to X-ray crystallography,Crystal growth, evaluation and mounting, Symmetry and space group determination, Background theory for data collection, Data collection using four-circle diffractometers, Area detectors,Crystal lattices, Structure factors, Crystal symmetry, Structure solutions, Structure refinement, An introduction to maximum entropy, Least squares fitting of parameters, Practical aspects of structure refinement, Crystallographic Database, Structure solution from Powder Diffraction Data PHY(NCL):3-427: NMR spectroscopy: 2-0-0-2

Course Coordinator: Dr. P. R. Rajamohanan Quantum Mechanics of NMR, Multinuclear NMR spectroscopy, Periodic table of NMR, Heteronuclear double resonance experiments, Magnetization transfer and signal enhancement, NMR of diamagnetic and paramagnetic compounds, Multidimensional NMR: 2D NMR, 1H-1H correlations, Heteronuclear Correlation Spectroscopy, 2D Exchange (EXSY), 2D NOESY, ROESY, DOSY Structure elucidation of small molecules, NMR of macromolecules, Multidimensional NMR Spectra, NMR Spectroscopy of Solids, 2D experiments in solids, semi rigid systems: HR MAS, Magnetic Resonance Imaging: In Vivo NMR, Imaging, MRI, functional MRI, NMR imaging of materials. PHY(NCL):3-428: Small Angle Scattering Techniques: 2-0-0-2

Course Coordinator: Dr. K. Guruswamy SAXS and Fourier Transforms, General Theorems in Small Angle Scattering: Particulate systems: Porod and Guinier regimes, Pair density distribution functions, Single particle form factor for spheres, rods and plates, polydispersity, Structure factors for equilibrium concentrated particulate systems, measured structure factors for systems exhibiting polydispersity, Two phase systems: General Theorems, Detailed analysis of scattering from lamellar systems, relevance to semicrystalline polymers. PHY(NCL):4-001: CSIR-800 programme: 0-0-8-4

Course Coordinator: Dr. P. A. Joy PHY(NCL):4-002: Project proposal writing (I & II): 0-0-8-4

Course Coordinator: Dr. P. A. Joy

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6. CSIR-NEERI (National Environmental Engineering Research Institute, Nagpur) Ph.D Environmental Science Sl. Code No. No. 1

PHY(NEERI)-1-001

2

PHY(NEERI)-1-451

3

PHY(NEERI)-3-001

4 5

PHY(NEERI)-4-001 PHY(NEERI)-4-002

6 7

PHY(NEERI)-2-451 PHY(NEERI)-2-452

8 9 10

PHY(NEERI)-2-453 PHY(NEERI)-2-454 PHY(NEERI)-2-455

11 12

PHY(NEERI)-2-456 PHY(NEERI)-2-457

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PHY(NEERI)-3-451

14

PHY(NEERI)-3-452

15 16 17

PHY(NEERI)-3-453 PHY(NEERI)-3-454 PHY(NEERI)-3-455

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Course Title Compulsory courses Research Methodology, Ethics, Communication skills, lab safety Analytical & Instrumentation Techniques for Environment Advanced Self Study designed by Guide CSIR 800 Societal Programme Project Proposal Writing (I & II) Optional Courses Environmental Chemistry & Toxicology Environmental Biotechnology, Microbiology Ecology Environmental Genomics (+Lab) Air and Noise Quality Control Management Water and Wastewater Solid and Hazardous Waste Management Environmental Economics, Policy and Law (Seminar) Materials and Environmental Applications (+Lab) Bioremediation (+Lab) Advanced Treatment Systems Energy & Environment

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1 1 0 2 2 0 2 3 0 2 4 4 0 0 8 4 0 1 6 4 2 0 2 3 2 0 2 3 2 0 0 2 2 0 2 3 2 0 2 3 2 1 0 3 2 0 2 3 2 0 2 3 2 0 2 3 2 0 2 3 3 0 0 3 3 0 0 3

Brief Description of Courses at CSIR-NEERI (Course Level-Wise) PHY(NEERI):1- 001:Research Methodology:1-1-0-2 Course Coordinator: Mr. P.S. Dutt Quantitative methodology Application of statistical concepts/procedures. Graphs, numerical summaries. Normal distribution, correlation/regression analyses, probability, statistical inferences for one or two samples. Hypothesis tests, Chi-square tests. Conceptual understanding/application of statistics. Application of statistical concepts/procedures. Analysis of variance, covariance, multiple regression. Experimental design: completely randomized, block, split plot/repeated measures. Advanced theory, derivations of quantitative statistics. Descriptive statistics, probability, normal distribution. One-/two-sample hypothesis tests, confidence intervals. Chi square tests. One-way analysis of variance, follow up tests. Analysis of variance designs (two-/three-way), repeated measures, correlation, simple/multiple regression methods, non-parametric procedures, multivariate analyses. Survey methods, Principles of measurement, constructing questions/forms, pilot testing, sampling, data analysis, reporting. Students develop a survey proposal and a draft survey, pilot the survey, and develop sampling/data analysis plans. Oral and written communication, thesis writing. Creativity and out of box thinking Intellectual property fundamentals. Introduction to writing scientific papers. Ethics in Science Lab safety norms and guidelines PHY(NEERI)-1-451: Analytical & Instrumentation Techniques for Environment: 2-0-2-3 Course Coordinator: Dr. G.L.Bodhe Preparation of standard solution, ppm, ppb. Normal solutions Standard curves; Concept of accuracy, precision and error, Sample reservations, handling of samples and chemical in lab, Sample handling of Volatile and non-volatile organic compounds, pH metry, Solvent partitioning, Titrimetry, Gravimetry Instrumentation and analytical methods involved in the following techniques and their applications in environment: Colorimetry, Spectrophotometry, Fluorescence Spectroscopy, Visible, Atomic and Infrared spectrometry, Flame photometry, Atomic Absorption Spectroscopy Chromatography, Gas Chromatography, HPLC, Electrophoresis, X-ray diffraction, Xray fluorescence, X-ray Emission, Cytophotometry, Bomb colorimetrry, ICP-MS, Utilization of different techniques for analysis of Polycyclic Aromatic Hydrocarbons (PAHs), Pesticide residues, Polychlorinated Biphenyls in the Environment Basics of Microbiological analysis, Laminar flow, autoclaving etc, preparations of media for culture growth, Microscopy Handling of radioactive and hazardous samples, Determination of radionuclide in the environmental samples: gamma Final Draft

spectrometry, alpha particle spectrometry, beta particle spectrometry, liquid scintillation measurement Management of chemicals and waste generated in labs, safety measures while handling chemicals and instruments, familiarity about various symbols used on the bottles of chemicals etc. PHY(NEERI)-4-001: CSIR 800 Societal Programme Course Coordinator:

:0- 0- 8- 4

The students have to undertake a project in rural area for 6-8 weeks in line with CSIR-800 programme which is primarily prepared at empowering 800 million Indians by way of S & T inventions. The theme for the project may be chosen from CSIR-800 document and as per expertise available at NEERI. Students will choose the topics in consultation with Doctoral Advisory Committee (DAC). PHY(NEERI)-2-452 Environmental Chemistry & Toxicology Course Coordinator: Dr. R.J.Krupadam, Dr. K Krishnamurthy

2- 0- 2- 3

Stoichiometry – First and Second law of Thermodynamics – Gibb’s free energy – Chemical potential – Oxidation and Reduction, Nernt equation pH-pE diagrams, Chemical Equillibria, Acid – Base reactions – Solubility product ,Application in heavy metals removal– Solubility of gases in water –– Chemical kinetics – Colloids and Coagulation, water treatment- Sorption- Radio nuclides and nuclear energy. Transport and transformation of chemicals – Phase Interactions Degradation of food stuffs(carbohydrates, proteins), Detergents, Pesticides, hydrocarbons(aliphatic and aromatic) – Photolysis – Volatility – Classification of elements –– Complex formation –– Hydrophobic interactions – Chemical speciation. Photochemical reactions in the atmosphere- Degradation of VOCs– Chemical process for the formation of inorganic and organic particulate matter – Oxygen and Ozone chemistry.-Photochemical smog. Soil classification– Inorganic and organic components of soil –physical and chemical properties of soil- Acid -base and ion exchange reactions-Leaching-Salt affected soil. Principles of green chemistry – Clean synthesis, – Atom economy – Environmental factor ‘E’ and Quotient ‘Q’, Nano materials, CNT, TiO 2. Toxicants, Distribution, Metabolism of toxicants, sites of action, classification of toxicity – acute and sub-acute toxicity bioassay, Factors influencing toxicity, Elimination of toxicants, Methods of toxicity testing – Evaluation - statistical assessment, sediment toxicity, Bio- chemical markers/indicators, Toxicokinetics, Bioconcentration, Bio-accumulation and Bio magnification in the environment. Xenobiotics – Chemical carcinogenesis – Genotoxicity assays – Neurotoxicity, Skin toxicity, Immunotoxicity. Renal toxicity, Endocrine disruptors, hormones, receptors. Toxicity of monomers, solvents, intermediates, products – toxic substrates – Metals and other inorganic Chemicals, Organic Compounds – Persistent chemicals. Procedures for assessing the risk – Risk measurement and Mitigation of environmental disorders – Factors in risk assessment.

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PHY(NEERI)-2-453 Environmental Biotechnology, Microbiology 2 0 2 3 Course Coordinator: Dr. Mrs. A. Kapley Biological Treatment of Wastewater – Aerobic System, Biological processes for domestic and industrial waste water treatments; Aerobic systems - activated sludge process, trickling filters, biological filters, rotating biological contractors (RBC), Fluidized bed reactor (FBR), expanded bed reactor, Inverse fluidized bed biofilm reactor (IFBBR) packed bed reactors air- sparged reactors, Biological Treatment of Wastewater – Anaerobic System Anaerobic biological treatment - contact digesters, packed column reactors, UASB. Introduction, constraints and priorities of Bioremediation, Biostimulation of Naturally occurring microbial activities, Bioaugmentation, in situ, ex situ, intrinsic & engineered bioremediation, Solid phase bioremediation - land farming, prepared beds, soil piles, Phytoremediation. Composting, Bioventing & Biosparging; Liquid phase bioremediation suspended bioreactors, fixed biofilm reactors. Mining and Metal biotechnology – with special reference to Copper & Iron. Microbial transformation, accumulation and concentration of metals, metal leaching, extraction and future prospects. Microorganisms and energy requirements of mankind; Production of nonconventional fuels - Methane (Biogas), Hydrogen, Alcohols and algal hydrocarbons, Use of microorganisms in augmentation of petroleum recovery. Introduction - Xenobiotic compounds, recalcitrance. hazardous wastes biodegradation of Xenobiotics . Biological detoxification - market for hazardous biotechnology application to hazardous waste management - examples of biotechnological applications to hazardous waste management – cyanide detoxification - detoxification of oxalate, urea etc. - toxic organics - phenols. Classification of microorganisms – prokaryotic, eukaryotic, cell structure, characteristics, Preservation of microorganisms, DNA, RNA, replication, Recombinant DNA technology. Distribution of microorganisms – Distribution / diversity of Microorganisms – fresh and marine, terrestrial – microbes in surface soil, Air – outdoor and Indoor, aerosols, biosafety in Laboratory – Extreme Environment – archaebacteria – Significance in water supplies – problems and control. Concentration and detection of virus, Transmissible diseases. Nutrition and metabolism in microorganisms, growth phases, carbohydrate, protein, lipid metabolism – respiration, aerobic and anaerobic-fermentation, glycolysis, Kreb’s cycle, hexose monophosphate pathway, electron transport system, oxidative phosphorylation, environmental factors, enzymes, Bioenergetics. Transmission of pathogens – Bacterial, Viral, Protozoan, Indicator organisms of water – Coliforms - total coliforms, E-coli, Streptococcus, Clostridium, Control of microorganisms; Microbiology of biological treatment processes – aerobic and anaerobic,  -oxidation, β-oxidation, nitrification and denitrification, eutrophication. Factors influencing toxicity. Effects – acute, chronic, concentration response relationships. Test organisms – toxicity testing, Bioconcentration – Bioaccumulation, biomagnification, bioassay, biomonitoring, bioleaching. Final Draft

PHY(NEERI)-2-454 Ecology 2 0 0 2 Course Coordinator: Dr. Mrs. A. Juwarkar Objective To acquaint the students with the concept of ecology so that they get well versed with different ecosystems and try to relate them in their day to day life A brief history; Concept, and major branches Concept of Speciation: Types and process Extinction: A brief history and reasons Community Ecology: Concept, Characteristics and dynamics; Interactions; Developmentof community (Plant Succession); Parasitism; Prey-Predator relationship Population Ecology: Characteristics of Interactions;Regulation; Population genetics

population;

Dynamics

and

Aquatic Ecosystem: Fresh water and Marine system, their types, characteristics and components; Wetlands, their Significance and conservation, Eutrophication and remedial measures Terrestrial ecosystems: Major terrestrial biomes - Forest, Desert, and Grassland (a brief account); Relationship between Precipitation and temperature in determining the vegetation; Forest Types of India (a concise account) Biological Invasion: Concept; Pathways of Invasion; Process of Invasion; Mechanism of Invasions; Impact of Invasive Species - Ecological, Environmental, Economical; Some examples of major invasive plants and animals in India Sustainable Development: The Concept and strategies of sustainable development Biodiversity: Definition; levels of diversity; alpha, beta and gamma diversity, and their measurement; ‘Biodiversity Hotspots’ – concept and a brief account; Biodiversity hotspots of India: a short account; Concept of endangered and threatened species: IUCN Categories of Extinction; Names of a few endangered and threatened animals and plants (of India); Strategies for biodiversity conservation: Concept of Protected Area Networks -National Parks, Wildlife Sanctuaries, Biosphere Reserves (A brief account) PHY(NEERI)-2-455 Environmental Genomics Course Coordinator: Dr. H.J.Purohit

2 0 2 3

History of genetic engineering, restriction, modifying and polymerase enzymes used in genetic engineering, vectors used in genetic engineering of microbes, Bacterial hosts used in cloning and expression. MolecularTechniques: Isolation of nucleic acids (DNA, RNA, e-DNA, Metagenome), PCR, optimization of PCR, gene specific and degenerate primer design, automated DNA sequencing, pyrosequencing, Principles and techniques of nucleic acid hybridization an